LOCUS       NZ_KZ679082            22666 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Streptomyces sp. CS149 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ679082
VERSION     NZ_KZ679082.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS149
  ORGANISM  Streptomyces sp. CS149
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7754255)
  AUTHORS   Malmierca,M.G., Perez-Victoria,I., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Cooperative Involvement of Glycosyltransferases in the Transfer of
            Amino Sugars during the Biosynthesis of the Macrolactam Sipanmycin
            by Streptomyces sp. Strain CS149
  JOURNAL   Appl Environ Microbiol 84 (18), e01462-18 (2018)
   PUBMED   30006405
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7754255)
  AUTHORS   Olano,C., Malmierca,M.G., Mendez,C. and Salas,J.A.
  TITLE     Characterization of the biosynthesis gene cluster for the
            macrolactam sipanmycins: involvement of four glycosyltransferases in
            the transfer of two aminosugars
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7754255)
  AUTHORS   Olano,C., Malmierca,M.G., Mendez,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAR-2018) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 556.87x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 11:43:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,915
            CDSs (total)                      :: 6,834
            Genes (coding)                    :: 6,691
            CDSs (with protein)               :: 6,691
            Genes (RNA)                       :: 81
            rRNAs                             :: 12, 7 (16S, 23S)
            complete rRNAs                    :: 12, 7 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 52 of 144
            Pseudo Genes (incomplete)         :: 108 of 144
            Pseudo Genes (internal stop)      :: 12 of 144
            Pseudo Genes (multiple problems)  :: 27 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:40:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5180486
            Orig. end                         :: >5203152
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ679082.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Professor JA Salas
            laboratory.
FEATURES             Location/Qualifiers
     region          1..>22666
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="16"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..>22666
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>22666
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:>12666](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..>12666
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    28..43
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.71"
                     /tool="antismash"
     gene            134..1069
                     /gene="mshB"
                     /locus_tag="C6W96_RS24005"
                     /old_locus_tag="C6W96_23975"
     CDS             134..1069
                     /EC_number="3.5.1.103"
                     /GO_process="GO:0010125 - mycothiol biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mshB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063246.1"
                     /locus_tag="C6W96_RS24005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_23975"
                     /product="N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-
                     D-glucopyranoside deacetylase"
                     /protein_id="WP_107413201.1"
                     /sec_met_domain="PIG-L (E-value: 1.1e-26, bitscore: 92.7,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLPARRLLLVHAHPDDESINNGATMARYAAEGAHVTLVTCTLG
                     EEGEVIPPALARLTSDRDDALGPHRVGELAAAMRELGITDHRFLGGAGRYRDSGMMGAE
                     QNGRPGSFWSTPVDEAAAHLVEVIREVRPQVLVTYDPDGGYGHPDHIQTHRVAMRAADL
                     AADPAHGSGAPHTIAKIYWNRVEREVLEAAFDRLRATAPDAFPGIAAVADVPGVTEAGQ
                     ITAEIDGAAYAGAKSAAMRAHATQIAVDGPFFALSNDLGQPLLTTECYQLVRGVRGVAG
                     PERESDLFAGVPGADAPDTAGATDAQGGAA"
     gene            1066..1539
                     /locus_tag="C6W96_RS24010"
                     /old_locus_tag="C6W96_23980"
     CDS             1066..1539
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956268.1"
                     /locus_tag="C6W96_RS24010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_23980"
                     /product="DUF6113 family protein"
                     /protein_id="WP_107413202.1"
                     /transl_table=11
                     /translation="MSGTPKKARGRADSSHAPRRNAPPREPAPIGFAARPNPARIAAYL
                     GLAVLGALVALAGTLVQAAWFPGGLIIALAGSAGLFYGGRILTRTQIGALAPAAGWFIT
                     VFLLLSGRPEGDYVFGDELGLVLFMLGGTAVAVICATTSKVPQSAIHSGRSGT"
     gene            1859..4048
                     /locus_tag="C6W96_RS24015"
                     /old_locus_tag="C6W96_23985"
     CDS             1859..4048
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063243.1"
                     /locus_tag="C6W96_RS24015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_23985"
                     /product="hypothetical protein"
                     /protein_id="WP_107413203.1"
                     /transl_table=11
                     /translation="MDPPRPEEPKTETTLTTRIRINIPGSRPIPPVVMRTPMAESDISG
                     GGRSDTERTGATPRPGTPPAAPGVGASASAGAGAGAGSSDRSGGPSAGPNGGAPADRSR
                     DGGPAADPAPAEKPAREKSGSDWFAPRKAPAAGPAAPGQGGPGTGTGAPGGPGGPGGPG
                     GPGGPSAGGPGSGGLGGPASGGPGAGGPGGPASGGPGAGGPGSGGLGGPGPGGPGGAPD
                     GGAGRSRPDLPYFSDAPKPGGAPGAPGSGPARSALDSYGTEPPGGGPRATPGPGVRTPG
                     PSGPTTGPVTGTSSLTPNLDGVPGLGGPGPMVPGTPGGVPPRMSDDTAILTPQAPAPEP
                     GPGGHVSGDTLTSGIPVVPSEPRATFPGGPGTPGAPVTGHGGPGGPGGPGVPTPGPAAP
                     RPASQTAPAPAAPAKKGRSKLVLLGVAAVVLLGIAYGAGLLLNHAEVPKGTTVLGVDIG
                     GGTKEEAVTKLEAALGERAKTPLTLSVDGKEEKLDPEKAGLTLDSQETVRGAAGSDYNP
                     VSVIGSLFGGERPADPVIPVDEEKLGVALTDLAGASGSANDGTIRFEPNKAVAVPGKPG
                     KTLDAGQSLISVRDAYRAQVQTGKANVVELPVTTSEPTITKAELDRAMKEFAQPAMSGL
                     ITIKAGPKQIQFGPARSLPQILSMKPVDGRLVDVYDKKAIDTLLDGVFDGIMAVKADGK
                     KHQVGPDDVAQAMKTALTGKTPAERTVTISLTGEG"
     gene            complement(4158..5933)
                     /locus_tag="C6W96_RS24020"
                     /old_locus_tag="C6W96_23990"
     CDS             complement(4158..5933)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379170.1"
                     /locus_tag="C6W96_RS24020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_23990"
                     /product="coagulation factor 5/8 type domain-containing
                     protein"
                     /protein_id="WP_107413204.1"
                     /transl_table=11
                     /translation="MHAPPTAPRTRPRTRALGFAALAVAMLMSVPTAQTAFGEEAEAVP
                     GGGDLGPNVHVFDPSTPDIQGKVDEIFKKQESAQFGLDRHALMFKPGTYDNINAQIGFY
                     TQIAGLGLNPNDTTFNGDVTVDAGWFDGNATQNFWRSAENLTLNPVSGTNRWAVSQAAP
                     FRRMHVKGGLNLAPDGYGWASGGYISDSKIDGEVGPYSQQQWYTRDSSVGGWVNGVWNM
                     TFSGVEGAPANSFPEPPYTTLETTPISREKPFLYLDGDDYKVFVPEKRENARGVSWANG
                     TPAGESIPLDRFYVVKEGADAATINAAVEQGLHLLFTPGVYHIDETININRADTVALGL
                     GLATIIPDNGVTAIKVGDVDGVKLAGLLVDAGPVNSETLIEVGPENASADHSANPTSLQ
                     DVFVRIGGAGPGKATTSIVVNSDDTIIDHTWVWRADHGEGWGWETNRADYGVRVNGDDV
                     LATGLFVEHFNKYDVEWYGERGRTIFFQNEKAYDAPNQEAIQNGDTKGYAAYRVDDSVE
                     QHEGWGMGSYCYYNVDPTIIQEHGFKAPVKPGVKFHSLIVVSLGGNGQYEHVINDVGSP
                     TSGTETVPSQVVNFP"
     gene            6244..6750
                     /locus_tag="C6W96_RS24025"
                     /old_locus_tag="C6W96_23995"
     CDS             6244..6750
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446870.1"
                     /locus_tag="C6W96_RS24025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_23995"
                     /product="DUF4265 domain-containing protein"
                     /protein_id="WP_107413205.1"
                     /transl_table=11
                     /translation="MSSPARPERPSREADRIKVWFRLAPREDGPLPYETEGLWATRLGP
                     DTARVDNVPFLRDGVAEGETVRFRTDGDGVHWAGERVADSGNCTVRVLPVPDGPLGHDA
                     RAVHERLAGFGLTGEVFSADFPLVALTVPGGADLRGVKALLTRGRDEGWWHFEVSCVTD
                     AWRAA"
     gene            complement(6831..7415)
                     /locus_tag="C6W96_RS24030"
                     /old_locus_tag="C6W96_24000"
     CDS             complement(6831..7415)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956278.1"
                     /locus_tag="C6W96_RS24030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24000"
                     /product="sugar O-acetyltransferase"
                     /protein_id="WP_107413206.1"
                     /sec_met_domain="Mac (E-value: 1.1e-15, bitscore: 56.3,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDETRTGQKEAMLSGELYLADDPELAAEALHAAVLSERYNATSA
                     ADPEARRAALSELLGEVGEGVEVRPPLRVDYGYRTTIGPRTFINFGAVLLDVARITVGA
                     DVQMGPNVQLLTPTHPIDPEQRRAKWEAAEPITIGDNVWLGGGVIVCPGVTIGENTVVG
                     AGAVVTKDLPANVVAVGNPARVIRTIGEPEA"
     gene            complement(7412..8665)
                     /locus_tag="C6W96_RS24035"
                     /old_locus_tag="C6W96_24005"
     CDS             complement(7412..8665)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127359.1"
                     /locus_tag="C6W96_RS24035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24005"
                     /product="MFS transporter"
                     /protein_id="WP_107413207.1"
                     /transl_table=11
                     /translation="MRTYRELFRTPEFTPFFAAASVQTAAQTATGLALGTLVYARTGSP
                     LLSALAMFGPSLAQVAGALTLLSAADRLPPRAALTALALLSAGAAGVQAVPGLPLWAAF
                     AVLLVMGVAASPGGGVRYGLLNEIVPREGFLLGRSVLNMAGGAMQICGFAVGGALVAVF
                     SARGTLLIGAALYVVAAAVTRFGLTARPARATGRPSVGETWRTNASLWSSTPRRYVFLA
                     LWVPNGLVVGCESLYVAYAPGHAGLLFAGGALGMLAGDTLVGRFVAVRWRARLGAPLRL
                     LLAAPYLLFALRPGLPLALAVVVVASVGFAASLLLQERLLALTPPELSGQALGLSSSGM
                     LAMQGVGAAVAGGIAQLTSPATGMAAVAGLSVAVTLALAPGLRTPVDADGGRLLGADGS
                     PRASRTPRTAHPAPEETT"
     gene            8802..9782
                     /locus_tag="C6W96_RS24040"
                     /old_locus_tag="C6W96_24010"
     CDS             8802..9782
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611151.1"
                     /locus_tag="C6W96_RS24040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24010"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_107415050.1"
                     /transl_table=11
                     /translation="MGWWQVSADTLASSRFVVSPLAEALASLMVLERASAAHPGERAWL
                     ETHLPAYRRRAADDPVSALVIRSALAPRWTADFLTPAPVPAPPGQAPPSFAEELVRVRA
                     APPDRARADLAVALGGPLPAALDRDDLAERAADAVEWVWTHTVLPDWPRRRRILEADVV
                     ARTAQLGQAGWAGALNGMRPGVRWLGDSRLQINTYDNPPRELDRAQLLFIPVTPDRSWV
                     CWDIPHRYGLVYPCSGVLAEAAGSVPVPAALGALIGPARAAVLVLLASPLSTTQLVALT
                     GQGLGSVGRHLRILLDAGLVRRRRAGRSVLYFRTEAGDVLVHGAG"
     gene            10001..>12666
                     /gene="lanKC"
                     /locus_tag="C6W96_RS24045"
                     /old_locus_tag="C6W96_24015"
                     /pseudo=""
     CDS             10001..>12666
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446862.1"
                     /locus_tag="C6W96_RS24045"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="C6W96_24015"
                     /product="class III lanthionine synthetase LanKC"
                     /pseudo=""
                     /sec_met_domain="micKC (E-value: 4.9e-232, bitscore: 771.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 5.9e-12, bitscore: 44.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 9.7e-05, bitscore:
                     19.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPEYAAYCQADRRFYDAPHRSLGPGGAVDAESSFYAAVRGSAPE
                     GWTRSRRGDWLAYHPDGLRLPPQGWKIHVSAALDNAASVLGRVLAHCLEHRLAFKCIPN
                     AGLLALRNAKYADRAGSGKFITVYPPSEEAFPEVCTALMELLEGEHGPYILSDLRCGNG
                     PVHTRYGAFAARFCSGPDGRPVPAVADPRGRLVPDDRGPAFRVPSWVTPPGFLMPHLEA
                     RAAVGLAGLPYAVEKALHFSNGGGVYLGRDTRTGEQVVLKEARPYAGLAADGADAVARL
                     ERERTALEQLAGLDCVPDVLDVFEVGDHHFLVLQYIPGTTLNTVFARRFPLARQHPSPE
                     LLAEHAAWAEELYGQVERAVAAVHDRGIVISDLHMSNVMVDEEAGRIVLLDFEAASPAA
                     ERRRQIVANPAFVAPPDRRGTDIDRYALACLRLALYLPLTTLFGIDRTKAAGLARDIAR
                     AFPVPEEALRPAVEEILRGVRDARDTGEAGEAVSRTAPAAASGTAFAVGLRDWPRARDA
                     LTKAITASCTPERDDRCFPGDIAQFATATGGQSFAYGAAGVLHALHETGAPPCPPAEEW
                     LLRHAKDPASGSPLGFYDGLTGIAWTLHRIGRTAEAADLLRIILDQPLEGLAPGLHNGY
                     AGIGLALDDLARTASATDAPALSAAAARCTALAVRALVDGPPSPRTGLLHGASGIALLL
                     IRRYATTGDTALLDLAAGALRRDLERCRAGDDGALLVVEGKRLMPYVGSGSAGIAAVID
                     AYLAHRPDPDLEAAGRALLPAALSAFYVQPGLLRGSAGLLLHLAATPLCDPADRRRAID
                     RHTDLLGSHALPYGGGLAFPGEQLMRLSMDLATGTAGALLALGAASGRPTGLPFLPAAP
                     AAHPAATAAPQTGPFRG"
     gene            12714..12845
                     /locus_tag="C6W96_RS24050"
                     /old_locus_tag="C6W96_24020"
     CDS             12714..12845
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611153.1"
                     /locus_tag="C6W96_RS24050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24020"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_003966507.1"
                     /transl_table=11
                     /translation="MALLDLQAMDTPAEDSFGELATGSQVSLLVCEYSSLSVVLCTP"
     CDS_motif       12714..12779
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQAMDTPAEDSFGELAT"
                     /locus_tag="C6W96_RS24050_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12780..12845
                     /prepeptide="core"
                     /locus_tag="C6W96_RS24050_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="31.80"
                     /molecular_weight="2076.4"
                     /monoisotopic_mass="2075.1"
                     /core_sequence="GSQVSLLVCEYSSLSVVLCTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQAMDTPAEDSFGELAT"
                     /leader_location="[12713:12779](+)"
                     /alternative_weights="2094.4"
                     /alternative_weights="2112.4"
                     /alternative_weights="2130.5"
                     /alternative_weights="2148.5"
     gene            12939..14759
                     /locus_tag="C6W96_RS24055"
                     /old_locus_tag="C6W96_24025"
     CDS             12939..14759
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061642.1"
                     /locus_tag="C6W96_RS24055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24025"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_234389382.1"
                     /transl_table=11
                     /translation="MPLPHPDPSPGTASGTRRLARLHPAALTWLFLCSTGGALAALALP
                     AALGHTVGRLVSGGPVPWSGLLLCAALTLAETGCDAAAAVTGTTTTARLTASLRTRTAA
                     RILAAEPRRALALPTGDLTARLTARTADAASAPVTAAGAVAGVLLPLGALVGLFLIDVW
                     TGAALLLGAPLLVALLRTFTRHTADAGADYQRAQSLIAHRLTEALDGADTIRAARTGAR
                     EHRRVLEPLAALADHGRRTWTVYGRAVGRSGLLLPLLMLLVLAVAGLRLAAGAIGVGEL
                     VAASRYASLAVGIGALTGALGSLARSRAAARSLDPLLTLAPLPHRGLGPVPDAPGHLEL
                     RDVGVEQDGRPLLTGVHLTVPGGTSLAVVGRSGSGKSQLAAVAGRLLDPDAGSVLLDGV
                     PLSGMEPDRLRREVAYAFARPALLGTTVEDTIAHGPWTAPPDAVREAARAARADGFLAL
                     LPYGYATPLADAPLSGGERQRLGLARAFAHPGRLLILDDALSSLDTVTEHHVRRALDAR
                     AGRCTRIIVAHRLSSAARADRVAWLEDGRLRATGRHDELWQDPEYRALFSTDTGTADAG
                     GGSTGSTATGPGGTSGPEGAPSSLTAAETR"
     gene            14756..16555
                     /locus_tag="C6W96_RS24060"
                     /old_locus_tag="C6W96_24030"
     CDS             14756..16555
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061641.1"
                     /locus_tag="C6W96_RS24060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24030"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_107413209.1"
                     /transl_table=11
                     /translation="MKRGHDRARPARDTALRRVAREARPFLRARTAAILRLSGWSLLEF
                     AQTFLGGYGVARALDDGFLAGRPVTGLLWLAVAAVAVLPSLLAARGVFGRLADLVEPLR
                     DGLVRRAVARALSGALGRSGDVSTRSLSQVTHQSEIARDGWAGLVLTLRSFVFTAAGAV
                     TGLLALSPALLLIVLPPLVLGSALFLGTLPPMAARQRAYLAADEAYAAHAGELAASVRD
                     IAAAGTAERTVAGSRALAETQLAASRSLARWSAVRVVALAVCGRLPPLLLLLGAPWLLR
                     NGLTPGGLVGALTYLTQALAPAVQALMTMLGTAGGRLVVVLDRFTDAPPPPADEPAREA
                     SPPPAQGPARDTPVAELHEVTFAYGPRAHPVLDRLSLTVGAGEHLAVVGPSGSGKSTLA
                     AVLAGTERPTGGAVRWRGHPARPADATSVRVLLPQHAYVFTGTLRDNLRYLRPDVRDRE
                     IAAMADAVGLDALLSRLGSLDAAVEPDRLSQGERQLVALGRAYLAAPPLLILDEATSRL
                     DPAAETRAELAFAALPGALVVVAHRLGSARRADRTLVMDGPRTQCGTPGELLRTSALYR
                     DLSGLWEPGEEHAIRSTPPPSPV"
     gene            complement(16524..17129)
                     /locus_tag="C6W96_RS24065"
                     /old_locus_tag="C6W96_24035"
     CDS             complement(16524..17129)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127364.1"
                     /locus_tag="C6W96_RS24065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24035"
                     /product="response regulator transcription factor"
                     /protein_id="WP_107413210.1"
                     /transl_table=11
                     /translation="MTTVLLVHTVPLWRASLASLLGTGRGIEVRTAERGAIRAALNGHG
                     PDVLLTDLDCPGARDVLDELKTVTAPHGGTYPLAVLTRSDQPRGLRRAYEAGALGYIDK
                     YRPVDDLSEVMHKLADGGRHIDESLAFSLLQVADMPLSPRELSVLSMAEEGDNVAGMAA
                     RLHLTPGTVRNYLAAAIRKSGARNRLDAIRRAKEAGWI"
     misc_feature    complement(16707..16709)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    17203..17220
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(17215..17228)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            complement(17433..18314)
                     /locus_tag="C6W96_RS24070"
                     /old_locus_tag="C6W96_24040"
     CDS             complement(17433..18314)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956285.1"
                     /locus_tag="C6W96_RS24070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24040"
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="WP_107413211.1"
                     /transl_table=11
                     /translation="MSGLDSGAAERRRQFAEEARSERPDLALLCLLLGAEAGPVGPAEV
                     VPVTPGEPVPDPYGIDAAQIELDRLAGLLPYGSRSPAGWASALAELLGERCGFGGSSAD
                     YQRLDSSLLQQVLRRRRGLPILLSVVWIEVARRAGAPVYGVALPGHFVVGFGDREHPVL
                     ADPFAGGAPLTGQDAELLVTGATGAALEPSMMVPARPLEIVLRILNNIRAWAAARPERT
                     DVALWAVELSLLLPSHPARLRYERAQLLVQRGEFLRGAAEMEEYAEILAGIEPTTAENI
                     RRKARAARALLN"
     gene            complement(18412..19407)
                     /locus_tag="C6W96_RS24075"
                     /old_locus_tag="C6W96_24045"
     CDS             complement(18412..19407)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061638.1"
                     /locus_tag="C6W96_RS24075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24045"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_107413212.1"
                     /transl_table=11
                     /translation="MEFTIGGRLEVRITPADVGKRVSVRRRTDGGGTGAEFTDVVGVLT
                     SWNDGVVSITRKSGESVHIVESSLVAGKVVPAAPARRRGPAASFDEMAAVTARAWQPVE
                     SEALGDWRLRAAGGFTRRANSVLPLGDPGLPLGEALGRVRRWYEERGLPAYVQTATGAE
                     GTQELLCAELEDHGWRREVSAEVRIAALAPVGDREAKVSAVRLTREPDAAWLARYQRFS
                     TPGPHVLRVLGSGPSVWFATVPGSGEEPDAIGRCVVDGRWAGFMAVEVAPEQRRRGLAT
                     TVMTALARRALDEGASAAWLQVEEDNEGARALYDGMGFAGHHRYHHYRSA"
     gene            19525..19845
                     /gene="fdxA"
                     /locus_tag="C6W96_RS24080"
                     /old_locus_tag="C6W96_24050"
     CDS             19525..19845
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950253.1"
                     /locus_tag="C6W96_RS24080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24050"
                     /product="ferredoxin"
                     /protein_id="WP_003966501.1"
                     /transl_table=11
                     /translation="MTYVIAQPCVDVKDKACIEECPVDCIYEGQRSLYIHPDECVDCGA
                     CEPVCPVEAIFYEDDTPEEWKDYYKANVEFFDDLGSPGGASKLGLIERDHAFVAGLPPQ
                     NQ"
     gene            19952..21046
                     /locus_tag="C6W96_RS24085"
                     /old_locus_tag="C6W96_24055"
     CDS             19952..21046
                     /EC_number="2.6.1.17"
                     /EC_number="2.6.1.79"
                     /NRPS_PKS="Domain: Aminotran_1_2 (29-363). E-value:
                     1.4e-44. Score: 144.6. Matches aSDomain:
                     nrpspksdomains_C6W96_RS24085_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984558.1"
                     /locus_tag="C6W96_RS24085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24055"
                     /product="bifunctional succinyldiaminopimelate
                     transaminase/glutamate-prephenate aminotransferase"
                     /protein_id="WP_107413213.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-42, bitscore:
                     144.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVSSRLPVFPWDKLAPYKSTAQAHPDGIVDLSVGTPVDPVPEL
                     IQRALVAAADSPGYPTVWGTEALRDVLTGWVERRLGAVGVTHANVLPVVGSKELVAWLP
                     TQLGLGAGDKVAYPRLAYPTYEVGARLCGAEPVVYDDPTELDPAGLKLLWLNSPSNPTG
                     KVLSKDELTRIVAWAREHGVLVFSDECYLELGWDAEPVSVLHPDVCGGHYDGIVAVHSL
                     SKRSNLAGYRAAFIAGDAAVLGELLLIRKHGGMMTAAPVQAATVAALGDDVHVSEQRAR
                     YADRRLALRAALEAHGFRIEHSEASLYLWATRDEPCWDTVAYLAERGILVAPGDFYGPA
                     GASFVRVAFTATDERVAAAVKRLS"
     aSDomain        20039..21040
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6W96_RS24085_Aminotran_1_2.1"
                     /evalue="1.40E-44"
                     /label="C6W96_RS24085_Aminotran_1_2.1"
                     /locus_tag="C6W96_RS24085"
                     /protein_end="363"
                     /protein_start="29"
                     /score="144.6"
                     /tool="antismash"
                     /translation="IVDLSVGTPVDPVPELIQRALVAAADSPGYPTVWGTEALRDVLTG
                     WVERRLGAVGVTHANVLPVVGSKELVAWLPTQLGLGAGDKVAYPRLAYPTYEVGARLCG
                     AEPVVYDDPTELDPAGLKLLWLNSPSNPTGKVLSKDELTRIVAWAREHGVLVFSDECYL
                     ELGWDAEPVSVLHPDVCGGHYDGIVAVHSLSKRSNLAGYRAAFIAGDAAVLGELLLIRK
                     HGGMMTAAPVQAATVAALGDDVHVSEQRARYADRRLALRAALEAHGFRIEHSEASLYLW
                     ATRDEPCWDTVAYLAERGILVAPGDFYGPAGASFVRVAFTATDERVAAAVKRL"
     gene            complement(21145..21612)
                     /locus_tag="C6W96_RS24090"
                     /old_locus_tag="C6W96_24060"
     CDS             complement(21145..21612)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127370.1"
                     /locus_tag="C6W96_RS24090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_24060"
                     /product="ATP-binding protein"
                     /protein_id="WP_107413214.1"
                     /transl_table=11
                     /translation="MSLPLTRRIARAALLIAAGATPVVGAAGAASAAELPQTPNLGGLT
                     ALDGANAGDTLDSAARQGTQAAGETGGRLVGTALPAAGETVGKSAKVAVPAAQETVGQA
                     AGNAGQAVGGVTEAAGGDLPTDGLGDGLPTDSLGKGGLPTDALPLNGLPIG"
     misc_feature    21722..21737
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.37"
                     /tool="antismash"
     misc_feature    complement(21784..21798)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.11"
                     /tool="antismash"
     misc_feature    complement(22434..22447)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    22435..22448
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     misc_feature    22627..22642
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.19"
                     /tool="antismash"
ORIGIN
        1 ctccgatctg acgaccaacg tggcgggaat gatcagcagc atcaagttct gacccgggcg
       61 gccgaggacc ggcggccggc gggcgcgggg gcgcgggggc acggggggcc tccgggctcg
      121 tagggtggtc cccatgaagg acctccccgc ccgccgtctg ctgctcgtgc acgcgcaccc
      181 cgacgacgag tcgatcaaca acggcgccac catggccagg tatgcggccg agggcgccca
      241 cgtcaccctg gtgacgtgca cgctcggcga ggagggcgag gtcatcccgc ccgcgctcgc
      301 ccgtctcacc tccgaccggg acgacgcgct gggcccccac cgcgtcggcg agctggccgc
      361 ggcgatgcgg gagctcggca tcaccgacca ccgcttcctc ggcggcgcgg gccgctaccg
      421 ggactccggg atgatgggcg ccgaacagaa cggccgcccc ggctccttct ggtccacccc
      481 cgtggacgag gcggccgccc acctcgtcga ggtgatccgc gaggtccgcc cccaggtact
      541 ggtcacctac gacccggacg gcggctacgg ccaccccgac cacatccaga cccaccgggt
      601 cgcgatgcgc gccgccgacc tggccgccga cccggcgcac ggctccggtg ccccgcacac
      661 catcgccaag atctactgga accgggtgga gcgcgaggtg ctggaggccg ccttcgaccg
      721 gctgcgcgcc accgcgcccg acgccttccc cggcatcgcc gccgtggccg acgtcccggg
      781 cgtgaccgaa gcggggcaga tcaccgcgga gatcgacgga gcggcgtacg ccggggcgaa
      841 gtcggcggcg atgcgcgccc acgccaccca gatcgcggtg gacggcccct tcttcgccct
      901 ctccaacgat ctcggccagc ccctgctgac gaccgagtgc taccaactgg tgcgcggcgt
      961 tcgcggcgtg gccggtccgg agcgcgagag cgacctgttc gcgggcgtcc cgggcgccga
     1021 cgccccggac accgcgggcg ccacggacgc ccagggaggc gcggcatgag cggcaccccc
     1081 aagaaggccc gcggccgcgc ggactcctcc cacgcgccgc gacggaacgc accccccagg
     1141 gagcccgcgc ccatcggttt cgccgcccgg ccgaacccgg cccggatcgc cgcctacttg
     1201 ggcctcgcgg tcctcggcgc gctcgtcgcc ctcgccggaa ccctcgtcca agcggcctgg
     1261 ttcccgggtg ggttgatcat cgccctggcc ggctccgcgg gcctcttcta cggtggccgg
     1321 atcctgaccc gcacccagat cggcgcgctc gccccggcgg cgggctggtt catcacggtc
     1381 ttccttctgc tgagcggccg gccggagggc gactacgtct tcggcgacga actcggcctg
     1441 gtgctcttca tgctcggcgg aacagccgtc gctgtgatct gcgccaccac ctccaaggtg
     1501 ccgcaatcag ccatccacag cggccggtcc ggtacgtgaa gtgccaagtc cgggtcgccg
     1561 gcgaccccca caggtgtgag gcaggggtgg aggtttcccc cggtcgcgga gtgtccgacg
     1621 gcggcggcca gtatggtggt gcgcgcgccg agccgtcccc tggcctgcgg catgggggaa
     1681 gtacgggcgg cggagccaat cgggagaacc tgctttgagt cgtgaaactg acagttcgtc
     1741 ctccgggccc cagggccgcg gcggagccgc gtacccctcg ggtacgccgc cgtacggatc
     1801 ccgccagtat ccgtcgctcc acccgtcgca ggacggctct gacgagaacc cggaatccgt
     1861 ggatccgccc cggcccgagg aaccgaagac cgagacgacg ctgacgacgc gcatccggat
     1921 caacatcccc ggctcgcgtc ccatcccgcc ggtcgtcatg cgtacgccga tggcggagag
     1981 cgacatctcc ggcggcggcc gttccgacac cgagcgcacg ggcgcgaccc cgcgccccgg
     2041 cacgccgccg gccgcaccgg gcgtcggtgc gagcgcgagc gccggtgccg gtgccggtgc
     2101 cggatcctcg gaccgctccg gcggcccgag cgccggcccg aacggcggcg cgcccgcgga
     2161 ccggtcccgg gacggcggcc cggccgccga cccggcgccc gcggagaagc cggcccggga
     2221 gaagagcggc agcgactggt tcgccccgcg caaggccccg gccgccggcc cggcggcgcc
     2281 gggccagggt ggtccgggca cgggcacggg tgcgcccggc ggtccgggtg gccccggtgg
     2341 ccccggtggc cccggtggtc ccagcgcggg cggcccgggt tcgggtggcc tcggcggtcc
     2401 cgcctccggt ggtcccggcg cgggcggtcc aggtggtccg gcctccggcg gtcccggtgc
     2461 gggcggtccc ggctccggcg gcctcggcgg tcccggtccg ggtggccccg gcggcgcgcc
     2521 cgacgggggc gcgggccgtt cgcgccccga cctgccgtac ttctcggacg ccccgaagcc
     2581 cggcggcgca ccgggtgcgc ccggctccgg ccccgcccgc agtgcgctcg acagctacgg
     2641 caccgagccc cccggcggcg gcccgcgtgc cacccccggc cccggagtgc gtacgcccgg
     2701 cccgtccggc cccaccacgg gaccggtcac cggcacctcc tcgctgaccc cgaacctcga
     2761 cggcgtcccg ggcctcggcg gccccggccc gatggtcccg ggcacccccg gcggcgtacc
     2821 gccccggatg tccgacgaca ccgcgatcct cacgccgcag gccccggcgc ccgagcccgg
     2881 ccccggcggc catgtctcgg gcgacacgct gacgagcggc atccccgtgg tgcccagcga
     2941 gccgcgcgcc acgttcccgg gcgggccggg cacccccggc gccccggtga cgggccacgg
     3001 aggtcccggc ggaccgggcg gaccgggtgt tcccacgccg ggccccgccg ccccgcgccc
     3061 cgcgtcgcag accgcgccgg cccccgccgc ccccgcgaag aagggccgct ccaagctggt
     3121 cctgctcggg gtcgccgcgg tcgtcctgct cggtatcgca tacggggcgg gcctcctgct
     3181 gaaccacgcc gaggtcccca agggcaccac ggtgctcggc gtcgacatcg gcggcggcac
     3241 gaaggaagag gcggtcacca agctcgaagc cgccctcggt gagcgggcca agacgcctct
     3301 gacgctgtcc gtggacggca aggaggagaa gctcgacccc gagaaggccg ggctcaccct
     3361 ggacagccag gagaccgtgc gcggcgcggc gggcagcgac tacaaccccg tctcggtgat
     3421 cggttcgctg ttcggcgggg agcgccccgc cgacccggtg atcccggtcg acgaggagaa
     3481 gctcggcgtg gcgctgaccg acctggcggg cgcctccggc tcggccaacg acggcacgat
     3541 ccgcttcgag ccgaacaagg ccgtggcggt gccgggcaag ccgggcaaga cgctggacgc
     3601 cggccagtcc ctgatctcgg tccgggacgc ctaccgcgcc caggtgcaga ccgggaaggc
     3661 caacgtggtc gagcttcccg tcaccaccag cgaacccacc atcaccaagg ccgaactgga
     3721 ccgggcgatg aaggagttcg cccagcccgc gatgtccggc ctgatcacca tcaaggccgg
     3781 tcccaagcag atccagttcg gcccggcccg gtcgctgccg cagatcctgt ccatgaagcc
     3841 ggtggacggc cgactggtcg acgtctacga caagaaggcg atcgacacgc ttctcgacgg
     3901 cgtcttcgac ggcatcatgg ccgtcaaggc cgacggaaag aagcaccagg tcggcccgga
     3961 cgacgtggcc caggcgatga agaccgccct gaccgggaag accccggccg agcgcacggt
     4021 caccatcagc ctgaccggcg agggctgagc ccggcggacg cggcgaagcg gggcccggcg
     4081 ctcatcagca gccgggcccc gcttccgtag ggttcccgta gcagttcccg tagcagtccc
     4141 cgtagcggga aagtgagcta cgggaagttc accacctggg acgggaccgt ctccgtgccc
     4201 gatgtcgggg agccgacgtc gttgatcacg tgctcgtact ggccgttgcc gccgagcgag
     4261 accacgatca ggctgtggaa cttcacaccg ggcttcaccg gggccttgaa gccgtgctcc
     4321 tggatgatcg tcgggtcgac gttgtagtag cagtagctgc ccatgcccca gccctcgtgc
     4381 tgctcgaccg aatcgtcgac ccggtaggcc gcgtagccct tcgtgtcgcc gttctggatc
     4441 gcctcctggt tgggtgcgtc gtacgccttc tcgttctgga agaagatcgt gcggccgcgc
     4501 tcgccgtacc actccacgtc gtacttgttg aagtgctcca cgaacagccc ggtcgccagg
     4561 acgtcgtcac cgttcacccg gaccccgtag tcggcccggt tggtctccca gccccagccc
     4621 tcaccgtggt ccgcccgcca cacccaggtg tggtcgatga tcgtgtcgtc gctgttgacg
     4681 acgatgctcg tggtcgcctt gccggggccc gcgccgccga tccgcacgaa cacgtcctga
     4741 agggaggtgg ggttggcgga gtggtcggcc gaggcgttct cggggccgac ctcgatcagc
     4801 gtctcggagt tcaccgggcc cgcgtcgacc aggagacccg cgagcttcac cccgtccacg
     4861 tcaccgacct tgatcgcggt caccccgttg tccgggatga tcgtggccag gccgaggccc
     4921 agggccacgg tgtccgcgcg gttgatgttg atcgtctcgt cgatgtggta gacgccgggc
     4981 gtgaagagca ggtgcaggcc ctgctccacg gccgcgttga tcgtggcggc gtccgccccc
     5041 tccttcacga cgtagaaccg gtccagcggg atcgactcgc cggccggggt gccgttggcc
     5101 catgagacac cgcgcgcgtt ctcacgcttc tccgggacga agaccttgta gtcgtccccg
     5161 tcgaggtaga ggaacggctt ctcgcgcgag atcggcgtgg tctccaacgt ggtgtacggc
     5221 ggctcgggga agctgttggc cggtgcgccc tcgacgcccg agaacgtcat gttccagacg
     5281 ccgttgaccc agccgccgac cgagctgtcg cgggtgtacc actgctgctg cgaatacggg
     5341 cccacctcgc cgtcgatctt ggagtcggag atgtagccgc cgctggccca gccgtaaccg
     5401 tcgggggcga ggttcagccc gcccttgacg tgcatccggc ggaagggcgc cgcctgggag
     5461 accgcccagc ggttggtccc ggagaccggg ttgagggtca gattctccgc cgaacgccag
     5521 aagttctgcg tcgcgttgcc gtcgaaccag cccgcgtcga cggtcacatc accgttgaac
     5581 gtggtgtcgt tcgggttgag gccgagaccc gcgatctgcg tgtagaagcc gatctgcgcg
     5641 ttgatgttgt cgtacgtccc cggcttgaac atcagcgcgt ggcggtcgag gccgaactgc
     5701 gcggactcct gcttcttgaa gatctcgtcg accttgccct ggatgtcggg cgtggacggg
     5761 tcgaagacat ggacgttcgg accgaggtcg ccgccgcccg gcacggcctc ggcctcctcg
     5821 ccgaaggcgg tctgggcggt gggcacggac atcagcatcg ccacggcgag cgcggcgaat
     5881 ccgagggccc gggtgcgcgg gcgggtgcgt ggtgcggtgg ggggagcatg catgaggtac
     5941 gtctcctggg tcgtggtaca tgtgcacgac gaacgggcga gagagcctgg ggggaggctg
     6001 tgggagagcg ctctctcgtg acgccgatgt ttcccctgtg ggcctgtacg cgtcaagagg
     6061 tgtgcatcag gagcctcaga agatgcggct gaatccaata actgggcctg aatgtcggga
     6121 aatcgacggt accggcgcga tgggtggcgg gcgctgactt caggagctga tgtcgtgcct
     6181 ggtcgtggtg gtggcggtgc tcgtggacag gcggacgtgc cgggcgcggg ggaccatggg
     6241 gccatgagtt cccccgcccg cccggagcgc ccgtcccgcg aagccgatcg gatcaaggtc
     6301 tggttccggc tggccccgcg cgaggacggg ccgctgccgt acgagacgga ggggttgtgg
     6361 gcgacgcggc tcggcccgga caccgcgcgg gtggacaacg tgcccttcct gcgggacggg
     6421 gtcgcggagg gcgagaccgt acggtttcgg acggacggcg acggggtgca ctgggccggc
     6481 gagcgggtgg cggactcggg caactgcacc gtacgggtgc tgcccgtgcc ggacggtccg
     6541 ctcgggcacg acgcacgggc cgtgcacgag cggctcgccg ggttcgggct cacgggcgag
     6601 gtcttcagcg ccgattttcc gctggtcgcc ctgaccgtgc cgggcggcgc ggatctgcgc
     6661 ggggtgaagg cgctgctcac ccgggggcgc gacgagggct ggtggcactt cgaggtctcg
     6721 tgcgtcacgg atgcctggcg ggcggcgtga ccgtacgggc gtgtgaccgt acgggtgtgg
     6781 ggagcgccgg tgtgccggag agggccggtg cgccggagag ggccggtggg ttacgcctcc
     6841 ggctcgccga tcgtccggat cacccgggcc ggattgccga ccgccaccac gttcgcgggc
     6901 aggtccttcg tgacgacggc ccccgcgccg accaccgtgt tctcgccgat ggtcaccccg
     6961 gggcagacga tcaccccgcc gcccagccac acgttgtcgc cgatggtgat cggctcggcc
     7021 gcctcccact tggcgcggcg ctgctcgggg tcgatggggt gggtcggggt gagcagctgg
     7081 acgttcgggc ccatctggac gtccgcgccg acggtgatgc gggcgacatc caggaggacc
     7141 gcgccgaagt tgatgaacgt acgcggaccg atggtggtcc ggtagccgta gtcgacccgc
     7201 agcggcggcc gcacctccac gccctcgccc acctcgccga gcagctcgga cagggccgcg
     7261 cgccgggcct cggggtcggc ggccgacgtg gcgttgtagc gctcgctcag cacggccgcg
     7321 tgcagggcct ccgccgccag ttcggggtcg tcggcgaggt acagctcgcc ggagagcatg
     7381 gcttccttct ggccggtcct ggtctcgtcg ctcatgtcgt ctcttccggt gcggggtgtg
     7441 cggtgcgggg tgtacgggac gctcgcggtg atccgtccgc tccgagcagt ctgcccccgt
     7501 cggcgtcgac cggcgtacgc agccccgggg ccagcgccag cgtcaccgcc accgagagcc
     7561 ccgcgaccgc cgccatgccc gtcgcggggg aggtcagctg ggcgataccg cccgccacgg
     7621 ccgcgcccac cccctgcatc gcgagcatcc ccgaggagct gagcccgagc gcctggccgc
     7681 tcagctcggg cggggtgagg gccagcagcc gttcctggag cagcaggctc gcggcgaagc
     7741 cgacactcgc cacgacgacc accgccaggg cgaggggcag ccccgggcgc agcgcgaaga
     7801 gcaggtaggg cgcggccagg agcagccgca gcggagcccc gagccgcgcc cgccaccgga
     7861 cggccacgaa ccgcccgacc agcgtgtccc cggcgagcat ccccagcgcc ccgccggcga
     7921 agaggagccc ggcgtgcccg ggcgcgtacg ccacgtacag ggactcgcag ccgacgacga
     7981 gcccgttggg gacccagagg gcgaggaaga cgtaccggcg cggcgtggac gaccagagcg
     8041 acgcgttcgt ccgccaggtc tccccgaccg aggggcggcc ggtcgccctg gccggccggg
     8101 cggtcagccc gaaccgggtc acggccgccg cgacgacgta cagggccgcc ccgatcagca
     8161 gcgtgccgcg cgccgagaac acggccacca gcgccccgcc caccgcgaat ccgcagatct
     8221 gcatcgcgcc gcccgccatg ttcagcaccg agcggccgag caggaacccc tcgcgcggca
     8281 cgatctcgtt gagcagtccg taccgcacac ctccgcccgg cgacgcggcc acccccatca
     8341 ccagcagaac cgcgaacgcc gcccacaacg gcagccccgg gacggcctgg acaccggcgg
     8401 cccccgccga cagcagggcg agagcggtca gcgcggcgcg cgggggcagc cggtccgccg
     8461 ccgacagcag ggtcagcgct ccggccacct gggccagcga cggtccgaac atcgccagcg
     8521 ccgacagcag gggcgagccc gtccgcgcgt acacgagggt gcccagggcc agaccggtcg
     8581 cggtctgggc ggccgtctgc acggaggcgg cggcgaagaa gggggtgaac tccggggtcc
     8641 ggaagagttc gcggtaggtg cgcatggggg gagtctccgg acgccgtcac cggagccgta
     8701 ctgtttcgcg cggacgcgaa agcctggggc ggtcggcccg gggcggacag ggtggacggg
     8761 cccggcggac ggggccggca gagaacgggg cggtggtgtg cgtgggctgg tggcaggtca
     8821 gcgcggacac gctcgcgagc agccggttcg tcgtctcgcc gctcgccgag gccctcgcga
     8881 gcctgatggt cctggagcgg gcctccgccg cgcacccggg ggagcgcgcc tggctggaga
     8941 cccatctgcc cgcgtaccgg cggcgcgcgg ccgacgaccc ggtctccgcg ctggtgatcc
     9001 gctccgccct cgcaccccgc tggaccgcgg acttcctcac ccccgcaccg gtccccgccc
     9061 cgcccggcca ggcgccgccc tccttcgccg aggagctggt gcgggtccgg gccgccccgc
     9121 ccgaccgggc gcgcgccgat ctggccgtgg cgctgggcgg gcctctgccc gccgcgctgg
     9181 accgggacga cctcgccgag cgtgccgccg acgccgtgga gtgggtctgg acgcacaccg
     9241 tgctgcccga ctggccgagg cggcggcgga tcctggaggc cgatgtggtc gcccgtaccg
     9301 cccagttggg gcaagcgggc tgggccgggg ccctgaacgg catgcggccc ggtgtccgtt
     9361 ggctgggaga cagccggttg cagatcaaca cctacgacaa cccgccccgc gaactggacc
     9421 gcgcgcagct gctgttcatc cccgtcaccc cggaccggtc ctgggtctgc tgggacatcc
     9481 cgcaccggta cgggctggtg tacccgtgtt ccggcgtact cgccgaggct gccggaagcg
     9541 ttcccgtccc cgccgccctg ggcgcgctga tcggccccgc gcgggcggcc gtcctggtgc
     9601 tgctggcctc cccgctcagc accacgcagc tcgtcgcgct gaccgggcag gggctgggtt
     9661 cggtcggccg ccatctgcgg atcctgctgg acgccgggct ggtccgccgc cgccgggcgg
     9721 gccgctccgt gctctatttc cgtacggagg cgggcgacgt cctggtgcac ggcgcgggct
     9781 gaggagagcc gaaagcgccc ggtgcacgcc cccacgcgcc cccgctcgtc gccccttcag
     9841 ggcggggcga cgagcggata cgcatcagta cgtggtgcgc tccgcatggt tggcgcgcat
     9901 gtacgagtcg tgacaacggt gactatgggc accgctcgtc gttatgacaa cttctctctc
     9961 gccgcgaacg acgcggagga accgagtgag ggggccgtgc gtgaatccgg agtacgccgc
    10021 gtactgccag gcggaccgcc gcttctacga cgcaccccac cgttccctcg gaccgggcgg
    10081 agccgtcgac gcggagagct cgttctacgc ggccgtccgt ggctccgcac ccgaggggtg
    10141 gacccgctcc cggcgcggtg actggctcgc gtaccacccc gacgggctgc ggctgccgcc
    10201 ccagggctgg aagatccacg tctcggccgc cctcgacaac gcggcctccg tgctcggccg
    10261 ggtcctcgcc cactgtctgg agcaccggct cgccttcaag tgcataccaa acgccgggct
    10321 gttggccctg cggaacgcca agtacgccga ccgggcgggc agcgggaagt tcatcaccgt
    10381 ctacccgccg tccgaggaag cgttccccga ggtgtgcacc gccctgatgg agctcctgga
    10441 gggcgagcac ggcccgtaca tcctgagcga tctgcggtgc gggaacgggc ccgtgcacac
    10501 ccggtacggc gcgttcgccg cccgcttctg ctccggtccg gacggccggc ccgtgcccgc
    10561 cgtcgccgat ccgcggggcc ggctcgtccc ggacgaccgg ggccccgcct tccgcgtccc
    10621 ctcctgggtg accccgcccg gctttctgat gccgcacctc gaagcccggg ccgccgtggg
    10681 cctcgccggc cttccgtacg ccgtggagaa ggcgctgcac ttctcgaacg gcggtggggt
    10741 ctacctcggc cgcgacaccc gcaccggcga acaggtcgtc ctcaaggagg cccggccgta
    10801 cgccggtctg gccgccgacg gggcggacgc ggtggcgcgc cttgagcggg agaggaccgc
    10861 gctggagcaa ctggccgggc tggactgcgt accggacgtc ctggacgtgt tcgaggtcgg
    10921 cgaccaccac ttcctggtcc tccagtacat ccccggcacc accctcaaca ccgtcttcgc
    10981 ccgccgcttc ccgctcgccc ggcagcaccc gtcgcccgaa ctcctcgccg aacacgcggc
    11041 gtgggcggag gagttgtacg ggcaggtcga gcgggccgtc gcggcggtgc acgaccgggg
    11101 catcgtcatc agcgatctgc acatgagcaa cgtgatggtc gacgaggagg ccgggcggat
    11161 cgtcctgctc gacttcgagg cggcctcccc ggccgccgaa cgccgccgcc agatcgtcgc
    11221 caacccggcc ttcgtcgccc cgcccgaccg gcgcggcacc gacatcgacc gctacgcgct
    11281 cgcctgtctg cggctcgccc tgtatctgcc gctcaccaca ctgttcggca tcgaccgcac
    11341 gaaggccgcc gggctcgcca gggacatcgc ccgcgccttc ccggtgccgg aggaggcgct
    11401 gcggccggcg gtcgaggaga tcctgcgggg ggtacgggat gcacgggaca cgggcgaggc
    11461 cggggaggct gtctcccgga cggctccggc agcggcttcc ggtacggctt tcgccgtcgg
    11521 cctccgcgac tggccccgcg cccgcgacgc gctgaccaag gccatcaccg cctcctgcac
    11581 accggagcgc gacgaccgct gcttccccgg ggacatcgcc cagttcgcca ccgccaccgg
    11641 cggccagtcc ttcgcctacg gggccgccgg agtgctccac gccctccacg agaccggcgc
    11701 cccgccgtgc ccaccggccg aggaatggct cctgcggcac gccaaggacc ctgcgtccgg
    11761 cagccccctc ggcttctacg acgggctcac cggcatcgcc tggaccctgc accggatcgg
    11821 ccgcaccgcc gaggccgccg acctcctccg gatcatcctc gaccagccct tggagggcct
    11881 cgcgcccggg ctgcacaacg ggtacgcggg catcggcctc gccctcgacg acctggcccg
    11941 caccgcctcc gccaccgacg ccccggccct ctccgccgcc gccgcccgct gcaccgccct
    12001 cgccgtccgc gcgctcgtcg acggtccgcc gtcgccccgc accggactgc tgcacggcgc
    12061 gagcggcatc gcgctgctcc tgatccgccg gtacgcgacg accggggaca ccgccctgct
    12121 ggacctggcc gccggcgcac tccgccgcga cctggaacgc tgccgggccg gcgacgacgg
    12181 ggcgctcctc gtcgtcgagg gcaaacggct gatgccgtac gtcggttcgg gcagcgccgg
    12241 catcgcggcc gtcatcgacg cctacctcgc ccaccgcccc gacccggacc tcgaagcggc
    12301 gggccgggcc ctgctcccgg ccgcgctctc cgccttctac gtccagcccg gactgctcag
    12361 gggctcagcc ggactcctgc tgcacctcgc ggccaccccg ctctgcgacc cggcggaccg
    12421 gcggcgcgcg atcgaccgcc acaccgacct gctgggcagc cacgccctgc cgtacggcgg
    12481 cggactcgcc ttccccggcg agcagttgat gcgcctgtcg atggacctgg ccaccgggac
    12541 cgccggcgcc ctcctcgccc tgggcgccgc ttccggccgc cccaccggac ttcccttcct
    12601 gcccgccgct ccggcggcgc acccggccgc cacggcggcc ccacagaccg gccccttcag
    12661 gggtcgtggc aacaccaccg ttcagtaagc aaccgtcccc gaaaggacac atcatggcgc
    12721 ttctcgacct tcaggcgatg gacaccccgg ccgaggactc cttcggcgag ctcgccacgg
    12781 gcagccaggt ctcgctgctg gtctgtgagt acagctccct cagcgtggtc ctctgcaccc
    12841 cgtgacccgc accggccggc ccgtcggtgc gcaccaccga cgggccggcc ggccacgtgc
    12901 ccgcaggggc cgaccctgcc gacccgaaag gcgaccccgt gccgctgccg cacccggacc
    12961 cgagccccgg cacggcgtcc ggcacccggc ggctcgcccg gctccacccg gccgccctca
    13021 cctggctgtt cctctgctcc accggcgggg cgctcgccgc cctcgccctg cccgccgccc
    13081 tcggccacac cgtcggccgg ctcgtctccg gcgggcccgt gccctggtcc gggctgctgc
    13141 tctgcgccgc cctgaccctc gccgagaccg gctgcgacgc ggcggccgcc gtgaccggca
    13201 cgaccaccac cgcccggctc accgcgtccc tgcgcacccg caccgccgcc cggatcctgg
    13261 ccgccgagcc gcgcagggcc ctcgccctgc ccaccggtga cctcaccgcc cggctcaccg
    13321 cccgcaccgc cgacgccgcg tccgcgcccg tgaccgccgc cggagccgtc gcgggcgtcc
    13381 tgctcccgct cggcgcgctc gtgggcctct tcctcatcga cgtctggacg ggtgccgccc
    13441 tcctcctggg cgccccgctc ctcgtcgcgt tgctccgcac cttcacccgg cacaccgccg
    13501 acgccggggc cgactaccag cgcgcccagt cgctcatcgc ccaccggctc accgaggccc
    13561 tggacggcgc cgacaccatc cgcgccgccc gcaccggcgc tcgcgaacac cgccgggtcc
    13621 tggaacccct ggccgccctc gccgaccacg gccgccgcac ctggaccgtg tacgggcggg
    13681 ccgtcggccg cagcggactc ctgctgcccc tgctcatgct gctggtcctc gcggtcgccg
    13741 gactccgcct cgccgcgggc gcgatcggcg tcggcgaact cgtcgccgcc tcccgctacg
    13801 cgagcctcgc cgtcggcatc ggcgccctca ccggggcact cggctccctg gcccgcagcc
    13861 gcgccgccgc ccggagcctc gaccccctcc tcaccctcgc cccgctgccg caccgcggcc
    13921 tgggtccggt ccccgacgcc cccggacacc tcgaactccg ggacgtcggc gtcgaacagg
    13981 acggccggcc cctgctgacc ggcgtccatc tgaccgtccc cggcggcacg tccctggccg
    14041 tcgtcggccg ctccggctcc ggcaagtccc agctcgccgc agtcgccggg cggctgctcg
    14101 acccggacgc cggcagcgtt ctgctggacg gcgtcccgct gtccggcatg gaaccggacc
    14161 ggctccgccg cgaggtggcg tacgccttcg cccgccccgc cctcctcggc accaccgtcg
    14221 aggacacgat cgcccacggc ccctggaccg ccccgcccga cgccgtacgc gaagcggccc
    14281 gcgcggcccg cgccgacggg ttcctcgcgc tgctcccgta cgggtacgcc accccgctcg
    14341 ccgacgcccc gctctccggc ggcgaacgcc aacgcctggg gctggcccgc gcgttcgccc
    14401 acccgggccg gctgctgatc ctcgacgacg cgctgtccag cctcgacacc gtgaccgagc
    14461 accacgtccg ccgcgccctc gacgcgcggg ccgggcgctg cacccggatc atcgtcgccc
    14521 accggctctc ctcggccgcg cgggcggacc gggtcgcctg gctggaggac ggccggctcc
    14581 gcgcgacggg ccgccacgac gaactgtggc aggacccgga gtaccgggcg ctcttcagca
    14641 cggacaccgg cacggccgac gcgggcgggg gcagcacggg cagcaccgcc accggcccgg
    14701 gcggcacctc cggccccgag ggcgccccct cctccctcac cgcagcggag acgcgatgaa
    14761 gcgcggccac gaccgggcgc gccccgcgcg cgacaccgcc ctgcgccggg tcgcccgcga
    14821 ggcccggccc ttcctgcggg cgcgcaccgc ggcgatcctg cggctgtccg ggtggtccct
    14881 cctggagttc gcgcagacct tcctcggcgg atacggggtc gcccgcgccc tcgacgacgg
    14941 cttcctcgcc ggacgtccgg tgaccggcct tctctggctg gccgtcgccg ccgtcgccgt
    15001 gctgccctcc ctgctcgccg cccgaggggt gttcggccgg ctcgccgacc tggtggagcc
    15061 gctgcgggac gggctggtcc ggcgtgcggt ggcgcgggcg ctgtcgggcg cgctcggccg
    15121 ctccggcgac gtcagcaccc ggtccctctc ccaggtcacc catcagagtg agatcgcccg
    15181 cgacggctgg gccggactcg tcctgaccct gcggtcgttc gtgttcacgg ccgccggagc
    15241 cgtcaccggc ctgctggccc tctcgcccgc cctcctcctc atcgtgctgc cgcccctggt
    15301 cctggggtcc gccctgttcc tcggcaccct gccgccgatg gccgcccgcc agcgcgccta
    15361 cctcgccgcc gacgaggcgt acgccgcgca cgcgggcgag ctcgccgcct ccgtacggga
    15421 catcgccgcc gccggaaccg ccgagcggac ggtggccggg tcccgggccc tggccgagac
    15481 gcagctcgcc gcgtcccgtt cgctggcccg ctggtcggcc gtgcgggtgg tggccctcgc
    15541 ggtctgcggc cggctcccgc cgctcctgct gctcctgggg gcgccgtggc tgctgcggaa
    15601 cgggctcaca ccgggcggtc tcgtcggcgc gctgacctac ctgacccagg cgctcgcccc
    15661 cgccgtccag gcgctgatga ccatgctggg cacggcgggc ggccgcctcg tcgtggtcct
    15721 ggaccggttc acggacgccc cgcccccgcc cgccgacgaa ccggcccgag aggcctcgcc
    15781 gccgcccgct cagggccccg cccgggacac cccggtcgcc gaactccacg aggtcacctt
    15841 cgcgtacggg ccccgcgccc accccgtcct ggaccggctc tccctgacgg tcggggcggg
    15901 cgagcacctc gcggtcgtcg gcccgagcgg cagcggcaag tcgaccctgg ccgctgtcct
    15961 cgccgggacc gagcggccca ccgggggagc ggtgcggtgg cgggggcacc cggcgcggcc
    16021 ggccgacgcc acgtccgtac gcgtcctgct gccccagcac gcctatgtgt tcaccggcac
    16081 gctgcgggac aacctccgct acctccggcc cgacgtccgt gaccgggaga tcgcggccat
    16141 ggcggacgcg gtcggcctgg acgcgctgct ctcccggctc ggctccctcg acgcggccgt
    16201 cgaaccggac cggctctccc agggcgaacg gcagctcgtc gccctcggcc gcgcctatct
    16261 cgccgccccg ccgctgctga tcctcgacga ggccaccagc cggctcgacc cggccgccga
    16321 gacccgcgcc gagctggcgt tcgccgccct gccgggcgcg ctggtcgtcg tcgcccaccg
    16381 gctcggctcg gcccgtcgcg ccgaccggac cctggtgatg gacggcccgc gcacccagtg
    16441 cggcaccccc ggcgaactcc tgcgtaccag cgccctctac cgcgacctgt ccggcctctg
    16501 ggagcccggc gaggagcacg ccatcagatc caccccgcct ccttcgcccg tctgatcgcg
    16561 tccagccgat tccgcgcccc ggacttccgg atggcggcgg ccagataatt gcggaccgtc
    16621 cccggtgtca ggtgcagtcg cgcggccatt cccgccacgt tgtcaccctc ctcggccatg
    16681 gagagcacac tcaattccct cggcgataac ggcatgtcgg ccacctggag gagactgaag
    16741 gccagcgatt cgtcgatatg ccgtcccccg tccgccagtt tgtgcatcac ctcggacagg
    16801 tcgtccaccg ggcggtactt gtcgatgtag ccgagcgccc ccgcctcgta cgcccgccgc
    16861 aggccgcgcg gctgatcgct gcgggtgagc acggcgaggg gatacgttcc tccgtgcggt
    16921 gcggtgaccg tcttcagctc gtcgagtacg tcgcgtgcgc ccggacagtc gaggtcggtg
    16981 agcagcacat cggggccgtg gccgttcaat gcggcgcgta tcgcgccgcg ttcggcggtg
    17041 cggacctcta ttccccgccc cgtgccgagg agcgatgcca gcgatgcgcg ccacaacggc
    17101 acggtgtgga ccagcagcac ggttgtcatc aatctgccct cagctcttct cttccggccg
    17161 cccgacgcgg aatgcgatgg gtcgtgcgcg ccccgtgacg ggtttccagt tgagcgcatg
    17221 ggcattcgtg tacgccgacg aacgggccga ataacgtcac tgttgggcgc ggaagggggc
    17281 gttcggatgc aaaacgggag cgcacatcgc tcacgcacca atccgtctcg ccacggccgg
    17341 ggcgcttgca cgagtgaggc caggcggatt tcggcggatg cgcacatcca tggatccgcc
    17401 gatctgcgga tctccttacc ggagcgccgg gttcagttca gcagggcgcg cgccgcacga
    17461 gccttgcgcc ggatgttctc ggccgtcgtc ggctcgatcc cggcgaggat ctccgcatac
    17521 tcctccatct ccgccgcccc gcgcaggaac tcaccgcgct ggaccaggag ctgggcgcgc
    17581 tcgtagcgga gcctggccgg atgcgagggc aggagcagcg acagctccac cgcccacagg
    17641 gccacatccg tgcgctcggg ccgcgccgcc gcccacgccc ggatgttgtt caggatccgc
    17701 aggacgatct ccagcggacg ggcgggcacc atcatcgacg gctccagcgc cgccccggtc
    17761 gcccccgtga ccagcagttc cgcgtcctgg ccggtcagcg gtgcgccccc ggcgaacggg
    17821 tcggccagca ccgggtgttc ccggtcgccg aagccgacca cgaagtgccc gggcagcgcc
    17881 accccgtaca ccggggcgcc cgccctccgc gcgacctcga tccagacgac cgacaggagg
    17941 atcggcaggc cccggcggcg gcgcagcacc tgctggagga gcgaggagtc cagtcgctgg
    18001 tagtcggccg acgagccgcc gaatccgcac cgctcaccca gcagttcggc cagcgccgag
    18061 gcccagccgg cgggagagcg ggagccgtag ggcagcagcc ccgccagccg gtccagctcg
    18121 atctgcgcgg cgtcgatgcc gtacgggtca gggacgggct cccccggagt caccgggacg
    18181 acctcggccg ggccgaccgg tccggcctcc gcgcccagca gcaggcacag gagggcgagg
    18241 tccggccgct cggaccgggc ctcctcggcg aactgccgcc gccgctcggc cgccccggaa
    18301 tccagcccgc tcatgtccga cccacacccc tgctcgtcct gttcccgccc cggtcctgac
    18361 ctcggccccg gccccgctcc ccgaagcccg ccgcgtggcc catcgcgccg atcacgccga
    18421 gcggtagtgg tggtaccggt ggtggcccgc gaagcccatg ccgtcgtaca gcgcccgcgc
    18481 cccctcattg tcctcctcga cctggagcca ggccgccgaa gcgccctcgt ccagcgcccg
    18541 gcgggccagc gcggtcatca ccgtcgtggc cagcccgcgc cgccgctgct ccggcgcgac
    18601 ctccacggcc atgaacccgg cccaccggcc gtccacgaca caccggccga tcgcgtccgg
    18661 ctcctcgccg ctccccggca ccgtggcgaa ccagaccgaa gggccgctgc ccagcacccg
    18721 cagcacgtgc gggccgggcg tggagaagcg ctggtagcgg gcgagccagg ccgcgtccgg
    18781 ctcccgggtc agccggaccg cggatacctt cgcttcccgg tcaccgaccg gcgccagcgc
    18841 ggcgatccgc acctccgccg acacctcgcg ccgccagccg tggtcctcca gctccgcgca
    18901 caacagctcc tgcgtgccct cggccccggt cgccgtctgg acgtacgcgg gcaggccccg
    18961 ctcctcgtac cagcggcgga cgcgcccgag cgcctcaccg agaggcagac ccggatcgcc
    19021 gagcggaagc acggagttgg cgcgccgggt gaagccccct gccgcgcgca gccgccagtc
    19081 gcccagcgcc tcgctctcca ccggctgcca ggcgcgcgcg gtgacggccg ccatctcatc
    19141 gaaggaggcg gcggggcccc gccgccgggc cggggcggcg ggcacgacct tgcccgcgac
    19201 cagggaagat tccacgatgt ggacggattc cccgctcttt cgtgtgatcg agaccacacc
    19261 gtcgttccac gatgtgagca cgccgaccac gtcggtgaac tccgcgcccg tgccgccgcc
    19321 gtccgtccgg cgccgcacgg atacgcgttt gcccacgtca gcgggtgtga tgcggacttc
    19381 cagccgtccg ccgatggtga attccacagc tctgtccgcc cctcctgttc ggatcgtgcc
    19441 cgagaacgga gatactaggg gcgggcatcg acgacgccgc gctcccgcgc gagagccaac
    19501 gccctaccga ggaggaacga cagcgtgacc tacgtcatcg cgcagccttg tgtcgacgtg
    19561 aaggacaagg cctgcatcga agagtgcccc gtcgactgca tctacgaggg ccagcggtcc
    19621 ttgtacatcc acccggacga gtgcgtcgac tgtggagcct gtgagccggt gtgcccggtc
    19681 gaggccatct tctacgagga cgacactccg gaggagtgga aggactacta caaggcgaac
    19741 gtcgagttct tcgacgacct cggctcgccg ggcggtgctt ccaagctcgg tctcatcgag
    19801 cgcgaccacg cgttcgtcgc cggactgccg ccgcagaacc agtaagcggc ggcaccacgc
    19861 gcgcagcccg gtcccgtacg gctcgtcccc gtgcgggacc gagccgtttc ccgtgccgcc
    19921 gtatccgaac accccgagaa agcagagccc cgtgtccgca gtctcctccc gcctccccgt
    19981 cttcccctgg gacaagctcg cgccctacaa gtcgacggcc caggcccacc cggacggcat
    20041 cgtggacctg tccgtcggca ctccggtcga cccggtcccc gagctgatcc agcgggcgct
    20101 ggtcgccgcc gcggacagcc ccggctatcc gacggtgtgg ggcaccgagg ccctgcggga
    20161 cgtgctcacc ggctgggtgg agcgccggct cggcgcggtc ggcgtcaccc acgccaacgt
    20221 gctgccggtc gtcggctcca aggagctggt ggcctggctg ccgacgcagc tcgggctcgg
    20281 cgcgggcgac aaggtggcct acccccggct cgcctacccg acgtacgagg tcggcgcccg
    20341 gctctgcggc gcggagcccg tcgtctacga cgacccgacc gagctggacc cggcggggct
    20401 gaagctgctc tggctcaact cgccgtccaa ccccaccggc aaggtgctgt cgaaggacga
    20461 gttgacccgg atcgtcgcct gggcgcgcga gcacggtgtc ctcgtcttca gcgacgagtg
    20521 ctacctggag ctgggctggg acgccgaacc ggtctcggtg ctccacccgg acgtctgtgg
    20581 cggccactat gacggcatcg tggcggtcca ctcgctctcc aagcgctcca acctggccgg
    20641 ataccgggcc gcgttcatcg cgggcgacgc ggccgtcctc ggtgagctgc tgctgatccg
    20701 caagcacggc gggatgatga cggccgcccc cgtccaggcc gccaccgtcg ccgccctcgg
    20761 cgacgacgtg cacgtctccg agcagcgcgc ccggtacgcg gaccggcgcc tcgccctgcg
    20821 cgcggccctg gaggcgcacg gcttccggat cgagcacagc gaggcgagcc tctacctgtg
    20881 ggcgacccgc gacgagccgt gctgggacac cgtggcgtac ctcgcggagc ggggcatcct
    20941 ggtcgcgccc ggcgacttct acggcccggc gggcgcgagc ttcgtccggg tggcgttcac
    21001 cgcgacggac gagcgggtgg cggcggcggt caagcgcctg tcctgacccg gatacgcggg
    21061 agggcctgga tacgcggggc ccggatacgc gggagggcct gaggagtgcg cactcctcag
    21121 gccctccggc atgtgcgtgg gggatcagcc gatcggcagg ccgttcagcg gcagggcgtc
    21181 ggtgggcagg ccgcccttgc cgaggctgtc ggtgggcagc ccgtcgccga ggccgtcggt
    21241 cggcagatcg ccaccggcgg cctcggtcac cccgccgacg gcctggcccg cgttgcccgc
    21301 ggcctggccg acggtctcct gggcggccgg gacggcgacc ttggcggact tgccgacggt
    21361 ctcgcccgcc gccgggagcg cggtcccgac gagccggcca ccggtctcac cggcggcctg
    21421 ggtgccctgc cgggcggcgc tgtccagggt gtcgccggcg ttcgcgccgt ccagtgcggt
    21481 cagaccgccc aggttcgggg tctgcgggag ctctgcggcg ctcgcggcac cggccgcacc
    21541 gaccacgggg gtcgcgccag cggcgatcag cagcgcggca cgagcgatcc gacgggtcag
    21601 ggggagggac atgatgctcc ttcagcgggt tgtgcacgaa tttgtttgtc cggtgatcgg
    21661 acgcactgac aaccgcttcg ggggagggga aggttgcggc gggcgaaggt aaagactgag
    21721 taatgcgtcc gattatccgc agcggaagaa cccgggcaaa caatccatac cgccggggcc
    21781 cggtgaaccg tcacttccct tgccggacaa gggaatcggg gcagggtggc acggctgcgg
    21841 ggaagagggc gaaacgagtc cggggacgcg gcccccatgg cccgtacgag tgacggggcg
    21901 tactactgaa cgacctggat cctgaccgcg gtcgtgccct tttccttgcc cttcgcgcgt
    21961 tccgtccgcc agcccttacc ggcgtcccag acccggtccg catagctcac gcgctcgatc
    22021 cgcagcgcct cggactgcgc cacggcccag tgcgccagct cccagccgcg ccgcggcgac
    22081 gccttgtcct cggcccgcgc cgaggtcgcc gggacgggca ccgagaccgt cgaggcggcg
    22141 gacgcgcccg cggccttcgc ggcgggcagc acacccttgc cgaaggcccg caccagctcg
    22201 gcccgcaccc gcccggcatc ccccgggccc tcggccgtgg ccgtcgacgg ggtgcagttc
    22261 agcgaggccg ccctgcgccc ggtcagcgcg gccgccatca gcgcggcgtc cggctcgtgc
    22321 ttcgcgtacg cctgcgggaa cccgctgcgc tgcacgcgct gcgcggccac ggtcagcggc
    22381 aggcgcgaat agcccggaac ctcggccagg ccctcgtaga acttcccggc cgagtagacc
    22441 gggtccatga tctgttccac ggtgccccag ccctgcgagg gccgctgctg gaacaggccc
    22501 accgagtccc ggtccccgta gtcgatgttg cggagcgtgg actcctggag cgcggtcgcc
    22561 agcgcgatcg tcaccgcccg ctcgggcatg ccccgggtgg tgcccaccgc ggagatcgtc
    22621 gccgcgttga cggcctgggc caggctcatc tcgtaccgct gggtct
//
