LOCUS       NZ_KZ679082            31136 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Streptomyces sp. CS149 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ679082
VERSION     NZ_KZ679082.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS149
  ORGANISM  Streptomyces sp. CS149
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7754255)
  AUTHORS   Malmierca,M.G., Perez-Victoria,I., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Cooperative Involvement of Glycosyltransferases in the Transfer of
            Amino Sugars during the Biosynthesis of the Macrolactam Sipanmycin
            by Streptomyces sp. Strain CS149
  JOURNAL   Appl Environ Microbiol 84 (18), e01462-18 (2018)
   PUBMED   30006405
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7754255)
  AUTHORS   Olano,C., Malmierca,M.G., Mendez,C. and Salas,J.A.
  TITLE     Characterization of the biosynthesis gene cluster for the
            macrolactam sipanmycins: involvement of four glycosyltransferases in
            the transfer of two aminosugars
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7754255)
  AUTHORS   Olano,C., Malmierca,M.G., Mendez,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAR-2018) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 556.87x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 11:43:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,915
            CDSs (total)                      :: 6,834
            Genes (coding)                    :: 6,691
            CDSs (with protein)               :: 6,691
            Genes (RNA)                       :: 81
            rRNAs                             :: 12, 7 (16S, 23S)
            complete rRNAs                    :: 12, 7 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 52 of 144
            Pseudo Genes (incomplete)         :: 108 of 144
            Pseudo Genes (internal stop)      :: 12 of 144
            Pseudo Genes (multiple problems)  :: 27 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:40:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2482623
            Orig. end                         :: 2513759
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ679082.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Professor JA Salas
            laboratory.
FEATURES             Location/Qualifiers
     region          1..31136
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iii"
                     /region_number="10"
                     /rules="cds(LANC_like and DUF4135)"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..31136
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..23054
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23054
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13054](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13054
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(240..255)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            454..795
                     /locus_tag="C6W96_RS11265"
                     /old_locus_tag="C6W96_11240"
     CDS             454..795
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004992926.1"
                     /locus_tag="C6W96_RS11265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11240"
                     /product="RNHCP domain-containing protein"
                     /protein_id="WP_032765128.1"
                     /transl_table=11
                     /translation="MSSLDTFTCVRCGLTVAAYAPDGSRRNHCPSCLHSQHLVDHVEGG
                     RSDCEGRMTPISIAVLRTGDWMVVHRCTRCDELTSNPVCGDDNQLILMRMAVRPLAQPP
                     FPLEAFGDL"
     gene            818..1237
                     /locus_tag="C6W96_RS11270"
                     /old_locus_tag="C6W96_11245"
     CDS             818..1237
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056536.1"
                     /locus_tag="C6W96_RS11270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11245"
                     /product="RNHCP domain-containing protein"
                     /protein_id="WP_107411511.1"
                     /transl_table=11
                     /translation="MTRRKPRRGAGRRPQRAKDVLHGPAGARGDAFRCVGCRLDVPLAA
                     PGTAHRNHCPSCLVSLHVDGRVPGDRAAGCRGRMVPLSLSVRQDGEWMLIHHCLACGRL
                     SANRIAGDDNALALVRLALRPLADAAVPVRAMLAL"
     gene            complement(1294..1845)
                     /locus_tag="C6W96_RS11275"
                     /old_locus_tag="C6W96_11250"
     CDS             complement(1294..1845)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056538.1"
                     /locus_tag="C6W96_RS11275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11250"
                     /product="DinB family protein"
                     /protein_id="WP_107411512.1"
                     /transl_table=11
                     /translation="MTESAAEEWPEPPLAGTEAAAVLGALERQRATLAWKTSGLDAAGL
                     RATLGTSSVTLGGLLKHLAHVEDSHFARLWLGIPAGAPWNTVDWDNDPDWAYRTAAEDT
                     PEQLRTLWRESAARSRAVVEEALSTGGGLDQLGAYVTRGGGRPNLRRILLDLVEEYARH
                     VGHADLIRESVDGLTGEDPG"
     gene            complement(1857..4169)
                     /locus_tag="C6W96_RS11280"
                     /old_locus_tag="C6W96_11255"
     CDS             complement(1857..4169)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135427.1"
                     /locus_tag="C6W96_RS11280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11255"
                     /product="MMPL family transporter"
                     /protein_id="WP_234389251.1"
                     /transl_table=11
                     /translation="MQRNGRSQKDQEHGEDGRTTDGRPPALRRWGHFTAARPRLMIWAG
                     ILLTVAGLVLAAGAMDRLVLSRFESPGSESVRTRAVLEKEFGEGTPSVLLMVTARQGTV
                     DDAPVAAAARELEEELALRDGVADVASYWSRDGSPTLRGLDGKQALIIARMAGTVTEAR
                     TELATISPEFTRDEELFTVRVGGGDEIFRQVAEQSRQDFLRAEMIVFPLVLLLLFAIYR
                     RFAAAALTLGMGLFSVITTLALMHLVTYVTEVSTFAANLALVMGIGLGVDYSLFVINRF
                     REELRSGRPVPEAVAYTVGSAGRTVTFSGLTVLVSLSCLLLFPFPFLRSFAYAGVGTVL
                     TAVFAALVILPAALARLGHRVARKGPTGNSRTPEGWWHRTALRMMRHPLRYGVPALAVL
                     LALAAPVLGLTFGTPDERVLPEGVSSRVVQQEIRDNFAAEEMDAVQVLRRGQPGTAANS
                     AEIEATALALSRVPEVHQVDALTGSYADGARIAEPGAAAERFGHEKDTWYSVVATHEGL
                     NHDVDRLLSDIRETAAGEGPGQVRIGGYPAELSDFRAQLVDRLPLVLGLVLVVTFLVLF
                     LMTGSLLLPAKATLLNALSLGVMFGALVRIFQEGHLSGLLGFTPTGTIEPSIPILMFCV
                     AFGLSMDYEVLMLSRIKEEYDRTGDTLGAVATGLERSGPLITSAAVIMAASFATYASSG
                     VVFLKMLGLGMVAVILVDATLIRAVLVPVLMRLAGRANWWAPKPLRAVHRRWGLSESEP
                     TATETAEAAGATGAAVR"
     misc_feature    4167..4180
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.74"
                     /tool="antismash"
     gene            4340..5218
                     /locus_tag="C6W96_RS11285"
                     /old_locus_tag="C6W96_11260"
     CDS             4340..5218
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.4"
                     /locus_tag="C6W96_RS11285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11260"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_107411513.1"
                     /transl_table=11
                     /translation="MSGVLLRGRDEPAPRPGRAASDDVDPSRLTIRLFGPLVVSRGATP
                     LELGPPKQRALLAVLLLRPGMETGVDQLTEALWGQEYPAYAKNLIQKSVSGLRALLQPD
                     TADGPGAEIAWSGGGYRLDTGDADVDLYAYERLAVAGLAAAREGDLERAADLLEQARTM
                     STGPLVEGLDGPMMERERLFRQERFLTDMEVLAEVEMELGRHRYGVPLLHYAAHKYPMR
                     ERFVWLLMLALHRSDRGNEALVVYAGHRARIAAELGSEPGPALRALHARLLAQDPGLMT
                     LSTLRENDGSA"
     gene            complement(5422..6258)
                     /locus_tag="C6W96_RS11290"
                     /old_locus_tag="C6W96_11265"
     CDS             complement(5422..6258)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552741.1"
                     /locus_tag="C6W96_RS11290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11265"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_107411514.1"
                     /transl_table=11
                     /translation="MTNGDLARLSINQETIKQWSLPELAEGCGKAGIDKVGLWRAPVQA
                     YGVERTARLLADAGIGVTSLCRGGFFTALDPAERARALDDNRVAIDEAAALSTDTLVLV
                     SGGLPPGSRDLHGARERVAEALAELAPYAAARGVRLAIEPLHPMYASDRCVVSTLAQAL
                     DLAERFPAEQVGVVVDTYHLWWDDRAPEQIARAGAGGRIHSFQLADWITPLPAGVLLGR
                     GQLGDGSVDFRAFRRDVEAAGFDGPIEVEIFNEALWARDGAEVLAEVAERYVQHAC"
     gene            complement(6255..7409)
                     /locus_tag="C6W96_RS11295"
                     /old_locus_tag="C6W96_11270"
     CDS             complement(6255..7409)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124633.1"
                     /locus_tag="C6W96_RS11295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11270"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_107411515.1"
                     /transl_table=11
                     /translation="MTAPVPLPRGPYTPRATPLDLPPGAGTPSSRTVFSAAHVVADPYA
                     DIGPDDPAAVDWEATLAFRRHLWSHGLGVAEAMDTAQRGMGLDWAGAAELIRRSAAEAK
                     TVGGRIACGVGTDQLPTTGEVTLADVRAAYEEQLALAEEHGVQPILMASRALARAARGP
                     EDYLATYAHLLRQASEPVVLHWLGPMFDPALEGYWGSTDLDEATNTFLKVIAEHPDKVD
                     GIKISLLDAAREIDVRRRLPGGVRCYTGDDFNYPELIAGDERGFSHALLGIFDPLGPLA
                     AHAVRVLDTGDVAGFRALLDPTVELSRHLFQRPTRFYKTGVVFLAWLAGHQDHFTMVGG
                     LQSARSLPHLATAYELADGLGLFPDPELAAHRMRALLAVHGGAR"
     gene            complement(7406..8557)
                     /locus_tag="C6W96_RS11300"
                     /old_locus_tag="C6W96_11275"
     CDS             complement(7406..8557)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005317389.1"
                     /locus_tag="C6W96_RS11300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11275"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_107411516.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 2.2e-09, bitscore:
                     36.7, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 7.1e-26,
                     bitscore: 89.3, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRTVRIAMNGVTGRMGYRQHLVRSILAIREQGGLDLGDGEVVW
                     PEPVLVGRRAHALAELAERHGLTEWSTDLDAVLADDTVEIYFDAQVTSARVEAIKKAIA
                     AGKHVYTEKPTATDVEGALDLARLARDAGIKHGVVQDKIFLPGLRKLKRLIDGGFFGEI
                     LSVRGEFGYWVFEGDWQEAQRPSWNYRAEDGGGIVVDMFPHWEYVLHELFGQVTSVTAH
                     VRTHVPRRWDEQGKPYEATADDAAYGIFELTGGAVAQINSSWTVRVNRDELVEFQVDGT
                     HGSAVAGLRNCRVQHRSSTPKPVWNPDLPVTESFRDQWQEIPDNQEFDNGFKAQWELFL
                     RHVVQDAPYTWDLLAGARGVQLAELGMKSSAEGRRLAIPELTL"
     cand_cluster    8524..31136
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    8524..31136
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[18523:21136](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(18524..21136)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     misc_feature    complement(8569..8589)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    8581..8592
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            8667..9779
                     /locus_tag="C6W96_RS11305"
                     /old_locus_tag="C6W96_11280"
     CDS             8667..9779
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380887.1"
                     /locus_tag="C6W96_RS11305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11280"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_234389252.1"
                     /transl_table=11
                     /translation="MTVTLADVAARARVSPATVSRVLNGNYPVAASTRERVLRAVDDLD
                     YVLNGPASSLAAATSDLVGILVNDIADPFFGIMAGAAQTQIGGPGDGSGRAGGEKLAVI
                     CNTGGSPERELTYLTLLQRQRAAAVVLTGGAVENPAHQAAMAAKLAKLADAGTRIVFCG
                     RPPLPEGDALVAALAFDNRGGGRRLTEHLISLGHRRIGYVAGPPERTTTRHRLEGHREA
                     LRAAGLDDLPAGDGTADGSGGPAADDDRLVVHGPYDRRSGYEATLELLRRAPDVTAIVA
                     ANDTVALGACAAVRDQGMRIPQDISVAGFDDLPFSVDAVPALTTVRLPLFEAGARAGRL
                     AMGKENPPPGGIATIAAELMIRGSTAAPRG"
     gene            10001..13054
                     /locus_tag="C6W96_RS11310"
                     /old_locus_tag="C6W96_11285"
     CDS             10001..13054
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450767.1"
                     /locus_tag="C6W96_RS11310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11285"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_107411518.1"
                     /sec_met_domain="DUF4135 (E-value: 1.7e-104, bitscore:
                     348.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-25, bitscore:
                     88.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEKNLIDRGTSRRPAPAASAVSVASLHNAASEPWWLPGVVGGST
                     SGEPPWAAFAREAVAAAPRDVVVADRAYPGLSGFGPVVAPFVEAAAGRLRDALADGEPE
                     GDGGDGTPVLADFRRQLTRRLARIAARTLVTELHEARRLGRLSGEGPEERFRDFVALTA
                     RRDGLDRLVTGYPVLARLLATACLNTASAFAELVARLAADRHLLAPAGVFGAPDGGPGG
                     LGPAAGPGALTAVEAGAGDSHRGGRSVMLLRFADGTRLVYKPRPLAAHRHFNSLVEWFG
                     SLPGAPELRVLRVLDRGDYGWAEFVAERPCASGAETRQFYRRQGALLALLHALDGTDLH
                     HENLIACGPHPVLVDVETLFHPPLGPARSADPAARALHESVHRVGLLPQLLVGDTTALD
                     MSAIGGGRAASSPIETADWAEAGTDRMRLVRRAGRFTESANRPRLGAEAADPSAYTEAL
                     CDGFRAGYTAIHDHRDELLSPDGPLRRFAGDEVRVVPRPTWTYTTLLDESTHPDLMGDA
                     AERHRVLSLLRTPLLGVPALSGVEDEEIAELWCGDVPVFATRPGSGRVWSGTGRTVAGS
                     APEGSAPDAVAPTGLARVEAKVRAMDTVDRQDQERIIRTAMVSTSPEPPHRPGAGGRAP
                     GAATAPEPEQLLSAARSVGDQLVSLAYRHEGRTNWIGLELLGERYWRLTPMAADLAGGY
                     TGPALFLAQLAALTGVSRYAEAAREALAPVPGLLDALHGRADELGALGSGAYAGLGGIA
                     YALTEVGTLLGDREVLDLAGPAARLSCAANAAEDGYGVRGGAAGGLVSLLAVYRATGRP
                     QAWWGAVRCAERLAAAPAPETGGFADGAAGIGWALLRLAGAGGDARHRSAGLHALRRAT
                     ALTDAATDHGPAWCDGVAGVALAIADSPDAREDPELSGWLAARSGELAGIDPLADDSLC
                     HGESGLLELLGHSALPALLPGVRAAWVRRAGTLVAAADRAGPLCGTPGHVPHPGLLTGL
                     SGIGHGLLRAGFPDRIGSALLLDPSRAP"
     gene            13126..13323
                     /locus_tag="C6W96_RS11315"
                     /old_locus_tag="C6W96_11290"
     CDS             13126..13323
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056547.1"
                     /locus_tag="C6W96_RS11315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11290"
                     /product="hypothetical protein"
                     /protein_id="WP_093811236.1"
                     /transl_table=11
                     /translation="MKQFGESALQASGDIAHEGTPEHPAGQISLGSTGGLGARSRLLSA
                     AEGESGYSHDLPWTTMTSPW"
     gene            13403..16333
                     /locus_tag="C6W96_RS11320"
                     /old_locus_tag="C6W96_11295"
     CDS             13403..16333
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124639.1"
                     /locus_tag="C6W96_RS11320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11295"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_107411519.1"
                     /transl_table=11
                     /translation="MRATSPVIVGRDEEIGLLSSALDAVQRRSGRALFLVGEAGIGKSR
                     LVGECAYRAYGLGMPVLRGRATSTGLVVPFRPLAEALASRFRAAGTPTDPELAPYHPAL
                     ARLVPEWRRAGSPGYPETVVELAEALLRLLSVLGREAGCAILLEDLHDCDTETVAVVEY
                     VIDNLADLPILFLGTLRPEPGAALDLVRSAERRQAATVRDLSPLDDAQVRALTGACLET
                     GPREIPEAVHERLAGRAAGNPYLLEVLLADLLDTGRLRLTDGAWEAVEQPGDSIPSDIV
                     RSWARRLERLDEPVRDLLLASATLGSQFSVTVLQTVTGFEDRALFTHLRSAVEAGVIAP
                     DGAAPDRYTFRHSLTAEALISSLAPAERASLARRAAAAIEQSGEPLDEDGRQLVASLQL
                     AAGDRAGAARQFAEAGRRMLASGAHGSAVVLLERAHPLAAETDRAAVAESLAVARAEGG
                     DLDGALALADALPPVPARSEAAARRGQIHIDLAWAAVMAERTAEAALQVEAARVLLGPT
                     PSPGRRAALVVVDGYLALLPGLPGHGRPYRDPVETEQAVQKAAETAEAEGLPVVACQAW
                     QLLALLRREEGFDAADAALERMLSISTEHALPVWRVEALVRLGANAFMRTGDASRLLSA
                     RAAATDLGALLLTRTVDGLLAMNAVLCARWEEAQEIIDRSAEASARVGDLSAHRYLLLA
                     GATMAAHRGRRRDMDRALAAFRRAGGEQSLLVPLRSGLCRAFGALLEEDRERAAAGLDE
                     ALAWELDHPSYYYLSGRYGLRPLLRVLAGQADRTELEEARAAPGGCLAWNRQFLELADA
                     VLLGRKGDPAGAARMMASFAQRSGPFPVARHLGLRLVADAAREDGWGEPVAWLRTAEEF
                     FYGAGVQPVSAACRAALRQAGASVGQHRGGWDRIPSTLRTSGVTPREYEVFVLLPERPG
                     NQQIARRLSISPRTVEKHMASLLNKTGRADRAALCEFAAECAAEPA"
     misc_feature    14297..14299
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16549..18537
                     /locus_tag="C6W96_RS11325"
                     /old_locus_tag="C6W96_11300"
     CDS             16549..18537
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969054.1"
                     /locus_tag="C6W96_RS11325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11300"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_234389253.1"
                     /transl_table=11
                     /translation="MTRPPVRTGSAGSAGAAGAVHFSLLGPLTARRDGRELPLGPRKQR
                     LVLATLLARPNTPVPVDVLTDAVWPDDPPRTARKNLQVYISAARALLGAAGDGGADRLV
                     HGCGGYHLRIAEGELDTLRFGSLARAGRAAAERGDLPGAARLLREALDLWEGPPLHDLR
                     DSAGVADEADRLEARCLTVYEDWAEAEIELGRAAVAVDGLRDLVERHPLRERLRAAWMN
                     SLHQSGRQAEALAVYDDYRQLMARELGLEPSPAMAALYRSMLGRGREARRPAVSRRTPA
                     PVVLPAGTGAFTGRREELRGLLDVLGGGEERVVVVSGPGGAGKSALAVRAAHLLADPFP
                     DGRVHVRVRREDGTARGRAEVLAELGRWCGIAEARTEFPATAAGAEVPATAAGVEVPET
                     AGALAVLAEAWQEWQARHRALVVLDDVPDEASVRGLLPRSGKCAVLVTARGQLPGLAPV
                     HRIALPAPADGEALELLGKLIGAGRLRTDPAAALRIVRACGGLPLAVEVSGMRLAVLRH
                     LPLAEYADRLDDPSAALDELVAGDVSVRHRIASGWRDLAEPDRWVLGRLAGLADDGCFT
                     LDRATVALGCGERAAIRAVESLIDAGAVTSPAGEVTAHAALYEVPRLLCLFAREQTTAG
                     EPGTAAAGEQGAAGDRGGAPAVALSPG"
     gene            complement(18524..21136)
                     /gene="lanKC"
                     /locus_tag="C6W96_RS11330"
                     /old_locus_tag="C6W96_11305"
     CDS             complement(18524..21136)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380882.1"
                     /locus_tag="C6W96_RS11330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11305"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_107411521.1"
                     /sec_met_domain="micKC (E-value: 1.8e-209, bitscore: 696.4,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.1e-08, bitscore: 32.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGIQETQLYCLADRRYYDTPARLPDQETRYPLDTAEPPSGWRRV
                     AGGLWTSLLPADGEPAEQGWKIHVSTVPDEAARTLRDTAAICLRHRVPFKFLRSEQALL
                     LMSGKYMSRGSAGKFLTLYPPDETALTRLLDELTTALSGRRGPYILSDLRIGDAPVYVR
                     YGSFVDRWCRDARGDRVPALRHPSGELVPDERGVVFRTPAWVKVPELLRPHLAARAAAR
                     DDSFPYTVTEALQFSNAGGIYLARHRETGHRVVLREARPHCGLDAVGDDAVTRLEREHR
                     ALTALAGLDCVPKVYGVRTVWEHRFLMTEYVEGPTLLDEIVARFALVRGARTADELAPY
                     AAWVHHVTAQLGDALREIHGRGLRFGDLHPSNIILRPDGRLALVDFEYATELDDGTTPL
                     AGAPGLQAPPGTPGAEADAYALWATWLTMLMPLTEMASHDRVKALSLESWARERYGLAP
                     DAGPARPALLRAAERAAGRESEIAALLGGPTPDWAELRTRLIAGIHAGATPERRDRLFP
                     GDPKGFATGGTDLAHGAAGVLYALHRVGAPVPAAWTDWLAETARRRDPAAPGGLYDGLP
                     GAAVTLALLGRPDEGRELFARAAEAAHPSTSADLLTGRAGIALAAVRLAGAASGAPDPE
                     LLDTALRTAWDLDCLVRGETVAGGPEAPPSAGLLRGLSGAALLHLELHALTGEEWLLRA
                     ARTALYRDSGHCVAMDDGTVQVKDGRRHLLYLDQGSGGFALVARAYLARQEAPSLAGLL
                     PGVRKGCGNEFVREPGLFTGRAGLVATARQLEDEGPAGPEVLASVRNLSWHLVADGDRL
                     LVPGARLRRCSADLATGAAGLLLALHFLAGADTDVAATPGGDGHGRRPHDLLKLLTLG"
     gene            complement(21149..22465)
                     /locus_tag="C6W96_RS11335"
                     /old_locus_tag="C6W96_11310"
     CDS             complement(21149..22465)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124642.1"
                     /locus_tag="C6W96_RS11335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11310"
                     /product="MFS transporter"
                     /protein_id="WP_107411522.1"
                     /transl_table=11
                     /translation="MATPLRSNRDFRLLWMSGLFAVLGSQMSALALPLLILKETGSAVQ
                     AGTVGTVSICAVLITMLPGGVMADRVERRRLMRLCDVGSLLAVTALTVAVWNGHAPMVL
                     VLLVATAGAVLNSVYAPAAFGLLRAVVPPDQMGQATARLQARTATVRLVGPLVGGALFG
                     VHEALPFTAQFLGLFLSTVCVALVRTRSAAHKKAGSVLSRDELTAGLGFLWQLPYLRTV
                     LLVFGLGMNFAFGALTFTALAVFSEGGRSGLGGGFVITCVSAGALVGALLAPRLSPDRH
                     IRALLVVTCWSCVLTAGVLAWLSSPLVAGLLCAVCMCLSTVASIGFLSTLLVVTPEDRV
                     GRVQSAASFLSSIVQPFGPLAGGALLTALGPRNAFGVVGAVLAVSAAVMTLAPSVRSGA
                     VPPPANPAAPEADAEDSGAPAPHEAAPRPVPDAAGPGAL"
     CDS             complement(22679..22885)
                     /gene="allorf_2505302_2505508"
                     /locus_tag="allorf_2505302_2505508"
                     /protein_id="allorf_2505302_2505508"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTXXXXXXXXXWMEITMSENTKPAGDETNETPEVEAHSVLDLQET
                     SVQGGDTTDGNCISVLSVVEQQR"
     CDS_motif       complement(22736..22885)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MTXXXXXXXXXWMEITMSENTKPAGDETNETPEVEAHSVLDLQETSVQGG"
                     /locus_tag="allorf_2505302_2505508_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(22679..22735)
                     /prepeptide="core"
                     /locus_tag="allorf_2505302_2505508_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.20"
                     /molecular_weight="1892.0"
                     /monoisotopic_mass="1890.9"
                     /core_sequence="DTTDGNCISVLSVVEQQR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTXXXXXXXXXWMEITMSENTKPAGDETNETPEVEAHSVLD
                     LQETSVQGG"
                     /leader_location="[22735:22885](-)"
                     /alternative_weights="1910.1"
                     /alternative_weights="1928.1"
                     /alternative_weights="1946.1"
     assembly_gap    22855..22879
                     /estimated_length=25
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            23185..24372
                     /locus_tag="C6W96_RS11340"
                     /old_locus_tag="C6W96_11315"
     CDS             23185..24372
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010062915.1"
                     /locus_tag="C6W96_RS11340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11315"
                     /product="radical SAM protein"
                     /protein_id="WP_107411523.1"
                     /transl_table=11
                     /translation="MELAELVARRPFPAAGLLLGLTRRCPLSCAHCSTGSGPLTRQQPD
                     PAQLERFVGSFTEENRPDVVMLTGGEPLLLPALAERLSTLARASGSRTALLSGMFFARG
                     WSRRAGSRRGAGRARGHGTPGRGLTGGRGGALPPAILRAIRSVDHFSASLDVHHEREVS
                     RADVFRALHLVREEGVAVSLHLTGTGGSDPYLAGLTRAVEEEFDGRVPCLVNEVRPFGR
                     AASWARATRTGPDPAAASPCSMAAWPVVAFDGRVLACCNQDTVDRRPAPAHLDLGHIAE
                     DDWATVRRRALESPMLRMLRTVGPAHLAARYGSGPRPGSYCDGCRALGGDEAVAAGARS
                     VAGGAAGALLDLTAAMRGSREGAQGVVRRHGCAEYAPLVVTGEPARPETDGRDLR"
     gene            24399..25124
                     /locus_tag="C6W96_RS11345"
                     /old_locus_tag="C6W96_11320"
     CDS             24399..25124
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070799.1"
                     /locus_tag="C6W96_RS11345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11320"
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="WP_107414866.1"
                     /transl_table=11
                     /translation="MSTGASARLRTKLLLLEPEFRGATHHMWRAEGLLPRYRTYLCTMH
                     AVIRASVPLMELALDRLRPRAASGDPLAAPLAAYLAEHIREEEGHDSWLLEDLRAAGGT
                     PEDALGPLPSPLTASLVGSQYYWIEHHHPVALLGYIAVLEGYAPAPGLTDRIARRTGLP
                     AAALRTVREHSVLDTEHLDELYALLDRLPLGRDREAAVAVSALHSLDALTRLFVRLGRS
                     APAPSPRGAGPVSPMGVTS"
     gene            25121..25339
                     /locus_tag="C6W96_RS11350"
                     /old_locus_tag="C6W96_11325"
     CDS             25121..25339
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959336.1"
                     /locus_tag="C6W96_RS11350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11325"
                     /product="aroma-sacti cluster domain-containing protein"
                     /protein_id="WP_006124648.1"
                     /transl_table=11
                     /translation="MTGPPGNGERPPLPDALYEAGFPVDLLTEEQVEVLSGLTPEELTL
                     LLDVKSRLDAVGPEVQAHGEIAGGALF"
     gene            25471..28755
                     /locus_tag="C6W96_RS11355"
                     /old_locus_tag="C6W96_11330"
     CDS             25471..28755
                     /GO_process="GO:0009190 - cyclic nucleotide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0035556 - intracellular signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380877.1"
                     /locus_tag="C6W96_RS11355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11330"
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="WP_107411524.1"
                     /transl_table=11
                     /translation="MNCLSCQQDLPPTARFCSSCGTPCATASAAAPAAVTAAGPAAATP
                     PPSDERKPVTVLFCDLVGSTALSGVLDPETLRTVTLRYFEAMSAEIVARGGTPEKFIGD
                     AVMAVFGVPVVRDDDARRALAAALGMRRALARLNEELAATLGIELAIRIGVNTGQVVAG
                     SDRTARQALVSGETVNIAARLEQNAGRGEILIGPGTLLAAGPTVSAEPTGPLRLKGKRD
                     SVEAHRLLALGADDPELLRRFDVPFVGRDTERRVLDAALEGTVREGTAGLLRVTGEAGI
                     GKTRLVREWLAGRSASGGLAYGAGRCRSYGDHGTLAPLADAVRSLLAARESPEGAQEAA
                     DGPAVDGSAVGGLAVGGLAVGDAMALLSGGLLRDGTPNAPFEDMCAALATVLERAARVR
                     PVVLVLDDWHAAAPLLVRTAHRLTDGSGCAGVLVLCAGRPDGPEGPEGPDDGDGPPAGA
                     GALLQLTGLPYEEAARLAAVLAGPDGGAPGTDRLLERAGGNPLYLEQLLVGDRADAGGG
                     VNAPVGSGGAAGEELPPTLQALLGARIGALARAERDVVDLAAVIGREFTAPELVRLQSS
                     VRAAEGHGASARRQLVDEALEALGRRRLVESGPPGDRAAAEAYRFSSGLVHEVAYASLS
                     KRAKAERHAWAAELPSVLRSGDGAVGGHLERAYRYRAELGLLDDRARRLRDRAAAALGR
                     AGAQAAARSDLHWAHGLLERAVELSPGDPAATRRLGEVRVALGRAAEGAELLLRVRDGA
                     ADPVEAAHARLALAVLDPGGPGPAAVARTVLPVFEAAGDSVGRARAHLRLAQQFQRSGR
                     HEEAERDQARALEHAVLAGAEPERAGALGAIGISLWRGPVPVPAAVIRCRTLLAAHGAG
                     RPTVRVTLNCPLAVLYALQDAADDAYGCLAEAERLAGKLGFAEAEVFLPMFRATVEALS
                     GRSAAALDLLGRADAAARRTGAAGMRTAVALDAARLELDEGREDRAAERLAGVGDASGL
                     SRADAVDLAGLRARLTARDRPEEAAGWAEQAVRASLLTDSPLVQATAELDRAHTLAALG
                     RHPEAGAAARAAGAHFTGKGHRPGVRRVSGFLARPPLPMATTRERS"
     gene            28933..29748
                     /locus_tag="C6W96_RS11360"
                     /old_locus_tag="C6W96_11335"
     CDS             28933..29748
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380876.1"
                     /locus_tag="C6W96_RS11360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11335"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_234389491.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 5.1e-21, bitscore:
                     73.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLADAGPPLGRPAGPATGRGVRVCVVDSGVERDHPLVGPLAGSWV
                     VVKDGESGGITVEPTTTGDTCGHGTACAGIIRRTAPECEIHSVRVLGERFSGTGDILMA
                     GLRWAVEQRFDVVNLSLSTTRTRFAQELHSLADSAYFARTVIVASAHNTPVESFPWRFA
                     SVISVGSHQEDDPELHLYNPEPPVEFFGPGQNVTVPWLGGRTIRTTGNSFATPYVAGLC
                     ARVLSAHPRMTAFQLKNALYLSAANVRHAPRPSSPPAGDTGDTRDDSEN"
     gene            29732..30352
                     /locus_tag="C6W96_RS11365"
                     /old_locus_tag="C6W96_11340"
     CDS             29732..30352
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070801.1"
                     /locus_tag="C6W96_RS11365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_11340"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_199854368.1"
                     /transl_table=11
                     /translation="MTQRTDSALSPVSPTSPVIDAPRSELLQSVVDVARAIFGAEASSV
                     FLLDEEADELVFQAVSGQGEEFLVGRRFPAGRGIAGWVATSGEPMVVDDLSADPSFDRS
                     LAESTAYVPNALMAAPLISDARILGVLEVLDPSPQARSGVRELDLLAMFARQAAAALRV
                     ITPERVRDAEEHPVLAGPTLAGAQREDALKLLGSLERLLRGVG"
     misc_feature    30555..30569
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 acgcggcgga aagggcctct gcgggtgatg cactggccag gctggcggag ctgcggggct
       61 gatcccggcg gacggccgat cccgcaggcc gtaattcggt ggcccgtctc ccggacccct
      121 tgttacggtg ctcgctcccc gaccgcgggt tccgaccgcg ggtgacctct gggcgtgagc
      181 cctggaaagc agttgatgta tgccccggac agtgactccg agcctccctc gtcgcacctg
      241 tgacgccggg gtgaccgggc ctgaccgtcc gcggccgccg tacgcgaccg actgctgaca
      301 cctcacggac cgctgccgtc gcgcagccgt ccggccccgc tccccgtacg cccctgacgc
      361 gaggggtgct cggtacttcc ctgctgcttc gttcctcatc cttcggcaag gagtatccgg
      421 gtgtctcacg acaaccccca gcaccgctca gccatgtcct ccctggacac cttcacctgc
      481 gtccgctgcg gactgaccgt cgccgcgtac gcgcccgacg gcagccggcg caatcactgc
      541 cccagctgtc tgcactcgca gcacctcgtc gaccacgtcg agggcggccg ctccgactgc
      601 gagggccgga tgaccccgat ctccatcgcg gtgctgcgca ccggcgactg gatggtcgtc
      661 caccgctgca cccggtgcga cgagctgacc tcgaacccgg tctgcgggga cgacaaccag
      721 ctgatcctga tgcggatggc cgtacgtcca ctggcccagc cgcccttccc gctcgaagcc
      781 ttcggtgacc tgtgaaccgg gcgcacggga ggctccgatg acgcggcgca agccccgtcg
      841 gggagcggga cggcgtccgc agcgggccaa ggacgtgctg cacggaccgg ccggggcgcg
      901 cggtgacgcg ttccggtgcg tcggctgccg gctcgacgtc ccgctggcgg caccgggcac
      961 cgcccaccgc aatcactgcc cgtcctgcct ggtcagcctg cacgtggacg ggcgggtccc
     1021 gggtgaccgg gcggcgggat gccgtgggcg gatggtgccc ctgagcctgt cggttcggca
     1081 ggacggggag tggatgctca tccaccactg cctcgcgtgc ggacggctca gcgccaaccg
     1141 catcgcgggc gacgacaacg cgctggcgct cgtccggctg gcgctgcgac cgctcgcgga
     1201 cgcggcggtc cctgtgcggg cgatgctagc gctgtgatcc cgagggccgc ccggcacccg
     1261 ccgggcggcc ctcgggcagc tctgcgcttc agctcacccc gggtcctcgc ccgtcaatcc
     1321 gtcgaccgac tcgcggatga ggtcggcgtg gccgacgtgg cgggcgtact cctcgaccag
     1381 gtccaggagg atgcggcgga ggttggggcg tccgccgccg cgggtgacgt acgcgccgag
     1441 ctggtccagg ccgccgccgg tgctgagcgc ctcctcgacc acggcccggg agcgggccgc
     1501 cgactcccgc cacagcgtgc gcagttgctc gggggtgtcc tcggcggccg tgcggtaggc
     1561 ccagtccggg tcgttgtccc agtcgaccgt gttccagggc gcgccggccg ggatcccgag
     1621 ccagaggcgg gcgaagtggc tgtcctcgac atgcgccagg tgcttgagca gaccgcccag
     1681 ggtgacggag gacgtgccga gcgtggcccg cagtcccgcc gcgtccaggc cggaggtctt
     1741 ccaggccagc gtggcccgct ggcgttccag cgcgccgagg acggccgccg cctccgtacc
     1801 ggcgagggga ggttcgggcc attcttccgc tgcgctctcc gtcatggcgg cagatcctaa
     1861 cgaacggcgg ccccggtggc cccggcggct tcggccgtct ccgtggcagt cggctccgac
     1921 tcggagagcc cccacctgcg gtggaccgcg cgcaggggct tcggggccca ccagttggcc
     1981 cggcccgcca ggcgcatcag gaccgggacg aggaccgcgc ggatcagggt ggcgtcgacc
     2041 aggatcaccg cgaccatgcc gaggcccagc atcttcagga agacgacgcc cgaggacgcg
     2101 tacgtcgcga aggaggcggc catgatgacc gccgccgagg tgatgagcgg gccgctgcgc
     2161 tccaggcccg tagccaccgc gcccagggtg tcgcccgtgc ggtcgtactc ctccttgatc
     2221 cgcgacagca tcagaacctc gtagtccatc gagagaccga aggccacgca gaacatcagg
     2281 atcgggatgc tcggttcgat cgtgccggtc ggggtgaagc cgagcagccc ggacagatgc
     2341 ccctcctgga agatccggac cagggctccg aacatcacac cgaggctcag ggcgttgagc
     2401 agggtggcct tcgcggggag cagcaggctg ccggtcatca ggaacagcac gaggaacgtg
     2461 accaccagga cgagaccgag gacgagcggc agacggtcga ccaactgtgc gcggaagtcg
     2521 gacagttcag ccgggtagcc gccgatcctg acctggccgg gcccctcccc cgccgccgtc
     2581 tcgcggatgt ccgacagcag gcggtcgacg tcgtggttca ggccttcgtg ggtggcgacc
     2641 acggagtacc aggtgtcctt ctcgtggccg aaccgctcgg ccgcggcgcc cggttcggcg
     2701 atcctggcgc cgtcggcgta cgaaccggtg agcgcgtcga cctggtggac ctccgggaca
     2761 cgggacagag cgagcgccgt ggcctcgatc tccgcgctgt tcgccgccgt gcccggctgc
     2821 ccccgccgca gcacctggac cgcgtccatc tcctccgccg cgaagttgtc acggatctcc
     2881 tgctgcacga cgcgactgga caccccctcg ggcagcaccc gttcgtcggg ggttccgaag
     2941 gtgaggccga gcaccggggc cgccagggcc agcaggaccg ccagggccgg gacgccgtag
     3001 cggagcgggt gccgcatcat gcgcagtgcc gtgcggtgcc accagccctc cggtgtacgg
     3061 gagttgcctg tcggcccctt acgggcgacc cggtggccca gccgtgccag cgccgccgga
     3121 aggatcacca gggccgcgaa gaccgcggtc agtacggtgc cgacgcccgc gtacgcgaag
     3181 gagcggagga aggggaaggg gaacagcagg aggcaggaga gcgacaccag gacggtgagg
     3241 ccgctgaagg tgaccgtgcg gccggcgctg cccaccgtgt acgcgaccgc ctcgggcacc
     3301 ggccggcccg aacgcagttc ctcccggaag cggttgatga cgaacaggct gtagtccacg
     3361 ccgagcccga tgcccatcac cagcgccaga ttggcggcga acgtcgacac ctcggtgacg
     3421 taggtgacca agtgcatcag cgccagggtg gtgatcaccg agaagaggcc catgccgagg
     3481 gtcagggccg cggccgcgaa ccggcggtag atggcgaaga gcagcagcag gaccagcggg
     3541 aacacgatca tctcggccct caggaagtcc tgccgggact gttcggcgac ctggcggaag
     3601 atctcgtcgc ccccgcccac gcggaccgtg aacagctcct cgtcgcgggt gaactcgggc
     3661 gagatcgtgg cgagttccgt acgggcctcg gtgaccgtac cggccattct ggcgatgatc
     3721 agggcctgct tgccgtccag gccgcgcagg gtgggcgagc cgtcgcgcga ccagtacgag
     3781 gccacgtcgg cgacaccgtc gcggagcgcc agctcctcct ccagctcgcg ggccgccgcg
     3841 gccaccggtg cgtcgtcgac cgtgccctgc cgggccgtga ccatgagcag cacactgggg
     3901 gtgccctcgc cgaactcctt ctccaggacc gcccgggtcc tcaccgattc cgaacccggg
     3961 ctctcgaagc ggctcaggac gagccggtcc atcgcccctg cggcgagcac cagtccggcc
     4021 acggtcagca ggatgccggc ccagatcatc agacgggggc gggcggcggt gaagtgtccc
     4081 cagcggcgga gcgcgggggg tctgccgtcg gtcgtgcgtc cgtcctcgcc gtgttcctgg
     4141 tccttctggc tgcggccatt gcgctgcata cgttcgtctc cgggggaagc ggcgctcgtc
     4201 cgccgggcac ggcgagctgc gtcccggcca ccctcacgta cgccgctgga cggaacgctg
     4261 gacgatgcac tggagggaac ggagccgcca cgtagcctga aaagcgggaa cgaagcgttc
     4321 actgcgttca gggggagaca tgtcaggtgt gctgctgcgc ggccgggacg agcccgcccc
     4381 gagacccggg cgggcggcgt cggacgacgt cgatccgtcg cgcctgacca tccggctctt
     4441 cgggcccctg gtcgtcagcc ggggcgccac tcccctggag ctggggccgc ccaaacagcg
     4501 ggctctcctc gcggtgctgc tgctgcgccc gggcatggag acgggcgtcg accagctgac
     4561 cgaagccctg tggggccagg agtacccggc gtatgcgaag aacctcatcc agaagtccgt
     4621 ctcggggctc cgggccctgc tgcaaccgga caccgccgac gggccgggcg cggagatcgc
     4681 ctggtccggg ggcggttacc ggctcgacac cggcgacgcg gacgtcgacc tctacgccta
     4741 cgaacggctc gcggtcgccg gtctcgcggc ggcccgcgag ggcgacctgg agcgcgccgc
     4801 cgacctgctc gaacaggccc gcacgatgtc gaccgggccg ctggtggagg ggctcgacgg
     4861 gccgatgatg gagcgggagc gactgttccg ccaggagcgg ttcctgacgg acatggaggt
     4921 cctggccgag gtggagatgg agctggggcg gcaccgctac ggggttccgc tgctgcacta
     4981 cgccgcccac aaatacccga tgcgcgagcg tttcgtctgg ctgctgatgc tcgcgctcca
     5041 ccgctcggac cgggggaacg aggcgctcgt cgtctacgcc gggcaccgcg cccgcatcgc
     5101 cgcggagctg ggttccgagc cggggcccgc cctgcgcgcc ctgcacgcgc ggctcctcgc
     5161 ccaggatccc ggcctgatga ccctgtccac cctgcgggag aacgacggga gtgcgtaaga
     5221 ggggcgggaa gcgtagaagg gcgggaaagc ggaatggggc ccggcctcgc ggccggaccc
     5281 ccctcgcttt cccctcccgt cgggccttcc cgttcccccc ggacccctcc ccggaagtcc
     5341 cgacgccatg tgtgacccgg gagggtaccc aaaggttgca gccctttacg atctctttac
     5401 ctttggccgc gtgcggggct ctcagcaggc atgttgtacg tagcgctccg ccacttccgc
     5461 caggacctcc gccccgtcgc gggcccacag cgcctcgttg aagatctcca cctcgatcgg
     5521 gccgtcgaac ccggcggctt ccacatcgcg gcggaacgcc cggaagtcca cgcttccgtc
     5581 gcccagttgc ccccggccca gcagaacgcc cgccgggagc ggggtgatcc agtcggccag
     5641 ctggaaggag tggatacggc cgcccgcgcc cgcgcgggcg atctgctcgg gcgcccggtc
     5701 gtcccaccac aggtggtaag tgtcgacgac caccccgacc tgttcggccg ggaagcgttc
     5761 cgcgaggtcc agggcctggg cgagggtgga gaccacgcag cggtcggacg cgtacatcgg
     5821 gtgcaggggt tcgatcgcca ggcgtacgcc gcgcgccgcc gcgtacggag ccagctccgc
     5881 cagcgcctcg gccacccgct cccgggcccc gtgcagatcg cggctgccgg gcgggaggcc
     5941 gccggagacc aggacgaggg tgtcggtgga cagagccgcc gcctcgtcga tcgccacccg
     6001 gttgtcgtcc agggcgcggg cgcgctcggc ggggtcgagg gcggtgaaga agccgccccg
     6061 gcagaggctg gtgacgccga tcccggcgtc cgcgaggagc ctggccgtgc gctcgacgcc
     6121 gtacgcctgc accggggccc gccacaggcc gaccttgtcg atgcccgcct tgccgcagcc
     6181 ctcggcgagc tcaggcagcg accactgctt gatggtctcc tggttgatgc tcagacgtgc
     6241 caggtcgccg ttcgtcatcg tgcgcctccg tggacggcga gcagcgcgcg catgcggtgg
     6301 gcggccagct cgggatccgg gaacaggccg agcccgtcgg ccagttcgta cgccgtcgcc
     6361 aggtgcggca gcgagcgggc cgactggagt ccgccgacca tcgtgaagtg gtcctggtgg
     6421 ccggccagcc aggccaggaa caccacgccc gtcttgtaga aacgggtggg ccgctggaag
     6481 aggtgccggg acagctcgac cgtggggtcc aggagggccc ggaagcccgc cacgtctccc
     6541 gtgtccagca cccgtaccgc gtgtgccgcc agcgggccca acgggtcgaa gatccccagc
     6601 agggcgtggc tgaagccgcg ttcgtcgccc gcgatcagct ccgggtagtt gaagtcgtcg
     6661 cccgtgtagc agcgcacccc gccggggaga cgtcggcgga cgtcgatctc gcgggccgcg
     6721 tccaggaggg agatcttgat gccgtcgacc ttgtccgggt gttcggcgat gaccttgagg
     6781 aaggtgtttg tggcctcgtc gaggtcggtg ctgccccagt agccctccag ggccggatcg
     6841 aacatcgggc ccagccagtg caggaccacc ggttccgacg cctggcgcag gagatgggcg
     6901 tacgtggcga ggtagtcctc gggcccccgg gcggcgcggg ccagggcgcg cgaggccatg
     6961 aggatcggct ggacgccgtg ctcctcggcc agggcgagct gctcctcgta cgccgcgcgg
     7021 acgtccgcga gcgtgacctc gcccgtcgtc ggcagctggt cggtgcccac gccgcaggcg
     7081 atccggccgc ccaccgtctt cgcctcggcg gccgagcggc ggatcagttc ggccgcgccc
     7141 gcccagtcca ggcccatccc gcgctgcgcg gtgtccatgg cctccgcgac gcccaggccg
     7201 tgcgaccaga ggtggcggcg gaaggcgagc gtggcctccc agtcgacggc cgccggatcg
     7261 tccgggccga tgtccgcgta cgggtcggcg accacgtgcg ccgccgagaa gaccgtacgg
     7321 gaggacgggg tcccggctcc cggcggcaga tcgagcgggg tggcacgggg ggtgtacggg
     7381 ccccggggca gggggacggg agccgtcaca gcgtcagctc cgggatggcg aggcggcggc
     7441 cctcggcgga cgacttcatt cccagttcgg ccagttggac gccccgggcg ccggccagca
     7501 ggtcccaggt gtacggcgcg tcctggacga catggcgcag gaacagctcc cactgcgcct
     7561 tgaacccgtt gtcgaactcc tggttgtccg ggatctcctg ccactggtcg cggaacgact
     7621 cggtgaccgg gaggtccggg ttccagaccg gcttgggggt cgacgagcgg tgctggacac
     7681 ggcagttgcg cagccccgcc acagccgagc cgtgcgtccc gtcgacctgg aactcgacga
     7741 gctcgtcgcg gttgacccgt accgtccagg aggagttgat ctgcgcgacg gccccgcccg
     7801 tcagctcgaa gatgccgtac gcggcgtcgt cggcggtcgc ctcgtacggc ttgccctgct
     7861 cgtcccagcg ccgcggaaca tgcgtacgga catgcgcggt cacggaggtg acctggccga
     7921 acagctcgtg gagcacgtac tcccagtgcg ggaacatgtc gacgacgatg ccgccgccgt
     7981 cctccgcgcg gtagttccac gaggggcgct gagcctcctg ccagtcgccc tcgaagaccc
     8041 agtagccgaa ctccccgcgc acggacagga tctcgccgaa gaagccgccg tcgatcaggc
     8101 gcttcagctt gcgcaggccc ggcaggaaga tcttgtcctg gacgacgccg tgtttgatgc
     8161 cggcgtcgcg cgcgaggcgg gccaggtcga gggcaccctc gacgtccgtg gcggtcggct
     8221 tctcggtgta gacgtgcttg cccgccgcga tcgccttctt gatcgcctcc acccgggccg
     8281 aggtgacctg ggcgtcgaag tagatctcga ccgtgtcgtc cgcgagcacc gcgtccaggt
     8341 ccgtcgacca ctcggtcaga ccgtggcgct cggcgagttc cgccagggcg tgggcgcgcc
     8401 ggccgacgag cacgggctcg ggccacacca cctcgccgtc gccgagatcc aggcccccct
     8461 gttcgcggat cgcgaggatc gagcgcacca ggtgctgccg gtaccccatg cgtcccgtga
     8521 cgccgttcat ggcgatgcgc actgtcctgc gtgtcacgaa gtttcctcca tacagccgta
     8581 gcaagcgctt tctatcgaag atgacgctag cctgccgaca gcggccggac aagagggggc
     8641 cgcacgtgaa ctcacggagg acagcgatga cagtcaccct ggcggatgtg gcggcccgcg
     8701 cccgggtgtc cccggccacc gtctcccgcg tgctgaacgg caactacccg gtggcggcgt
     8761 cgacccggga acgggtcctg cgtgcggtgg acgacctgga ctacgtgctc aacgggcccg
     8821 ccagttcgct cgcggcggcc acgtccgacc tggtcggcat cctggtcaac gacatcgccg
     8881 acccgttctt cgggatcatg gcgggggccg cgcagacaca gatcggcggc cccggggacg
     8941 gctccgggcg ggcgggcggc gagaaactgg ccgtcatctg caacaccgga ggctccccgg
     9001 agcgcgagct gacctacctc acgctcctcc agcgccagcg cgccgccgcc gtcgtcctca
     9061 ccggcggcgc ggtcgagaac ccggcgcacc aggccgcgat ggcggcgaag ctggcgaagc
     9121 tcgcggacgc gggcacccgg atcgtcttct gcgggcggcc cccgctgccc gagggggacg
     9181 cgctcgtcgc cgccctcgcg ttcgacaacc ggggcggcgg ccgccgcctc accgagcacc
     9241 tgatctcgct cggccaccgc aggatcggtt acgtcgccgg gcccccggaa cgcaccacca
     9301 cccgccaccg gctggagggc caccgggagg cgctgcgcgc ggcgggactg gatgacctgc
     9361 cggcagggga cggtacggcc gacggctccg gcggcccggc ggccgacgac gaccggctcg
     9421 tcgtgcacgg gccctacgac cggcgctccg ggtacgaggc caccctcgaa ctcctgcgca
     9481 gggcaccgga cgtgaccgcg atcgtggccg ccaacgacac cgtggcgctg ggcgcctgcg
     9541 cggccgtacg ggaccagggg atgcgcatcc cgcaggacat ctcggtggcg ggcttcgacg
     9601 acctgccgtt ctcggtggac gcggtgccgg ccctcacgac ggtccggctg cccctcttcg
     9661 aggcgggcgc ccgggcgggg cggctcgcga tgggcaagga gaacccgccg cccggcggca
     9721 tcgcgacgat cgcggccgag ctgatgatcc gggggtccac ggcggcgccg aggggctgac
     9781 ccggccgcgg ggccggccgc caccgccgta cccggttcgg cgttcccggg ccgtgaggac
     9841 agctgcgggc cggagggcgt tcgccgctca tggggggtgc ctgcgggccg gagggcgaaa
     9901 gatgggggcg actcccccat gtgcccgtac cccctccccc gccacgatgg tcacgggcgg
     9961 cccgcacggg gccggtccgg gaccggggag gtgcggtgcg atggcggaga agaacctgat
    10021 cgacagaggt acgagccgcc gccccgcccc tgccgcctcc gccgtctccg tcgcctccct
    10081 ccacaacgcg gcctccgagc cgtggtggct gcccggggtc gtcgggggca gcacctccgg
    10141 cgaacccccc tgggccgcct tcgccaggga ggccgtcgcc gccgccccgc gcgatgtggt
    10201 ggtcgccgac cgcgcctacc cagggctcag cggcttcggg ccggtcgtcg cgccgttcgt
    10261 cgaggccgcc gcgggaaggc tccgggacgc gctggcggac ggggagcccg agggggacgg
    10321 gggcgacggg actcccgtac tggcggactt ccggcggcag ttgacccggc gactggcccg
    10381 gatcgcggcg cgcaccctcg tcaccgagct gcacgaggcc cggcggctgg gccggttgag
    10441 cggggagggg cccgaggagc gcttccggga cttcgtcgcg ctgaccgccc gccgcgacgg
    10501 cctcgaccgg ctcgtcaccg gctaccccgt gctggcccgc ctcctcgcga cggcctgcct
    10561 caacaccgcg tccgccttcg cggagctggt cgcgcggctc gccgccgacc ggcatctgct
    10621 ggccccggca ggggtgttcg gagccccgga cggcggtcct ggcgggctcg gcccggctgc
    10681 cgggccgggg gcgctcacgg cggtcgaggc cggtgcgggc gacagccacc gcggcggccg
    10741 gtcggtgatg ctcctgcggt tcgccgacgg cacccggctg gtctacaagc cgcgcccgct
    10801 cgcggcgcac cggcacttca actccctggt cgaatggttc ggttcgctgc cgggcgcccc
    10861 cgaactgcgg gtgctgcgcg tcctggaccg gggggactac ggctgggccg agttcgtggc
    10921 ggagcggccc tgcgcctcgg gggcggagac ccggcagttc taccggcgcc agggtgcgct
    10981 gctggccctg ctgcacgcgc tggacggtac ggatctgcac cacgagaacc tgatcgcctg
    11041 cggcccgcac ccggtcctgg tcgatgtgga gaccctgttc catccgccgc tggggcccgc
    11101 ccgctccgcc gatccggccg cccgggccct gcacgaatcc gtccaccggg tgggcctgct
    11161 gccccagttg ctcgtcgggg acaccaccgc gctcgacatg tccgccatcg gcgggggccg
    11221 ggccgcctcg tcccccatcg agaccgccga ctgggcggag gccggcaccg accgcatgcg
    11281 gctggtacgg cgagcggggc ggttcaccga gtccgccaac cggccccggc tcggcgccga
    11341 ggcggccgac ccctccgcgt acaccgaagc cctctgcgac ggattccgcg ccgggtacac
    11401 cgcgatccac gaccaccgcg acgaactcct ctccccggac gggccgttgc ggcggttcgc
    11461 cggggacgag gtgcgcgtcg tcccccggcc cacctggacg tacacgacgc tgctcgacga
    11521 gtcgacccac cccgatctga tgggggacgc cgccgaacgg caccgggtgc tgtccctgct
    11581 gcgcaccccg ctcctgggcg tgcccgcgct gtccggcgtg gaggacgagg agatcgcgga
    11641 gctgtggtgc ggtgacgtgc ccgtgttcgc cacccggccg ggctccggcc gggtgtggag
    11701 cggcaccggc cgtacggtcg cgggctcggc acccgagggg tccgcgcccg acgccgtcgc
    11761 ccccaccggt ctggcgcgcg tcgaggcgaa ggtgcgcgcg atggacaccg tggaccgcca
    11821 ggaccaggaa cggatcatcc ggaccgccat ggtgagcacc tcccccgagc cgccgcaccg
    11881 gcccggcgcg ggcggccggg ccccgggtgc ggcgaccgcg ccggagcccg agcaactgct
    11941 gtccgccgca cggtcggtgg gcgaccagct cgtctccctc gcctaccggc acgagggccg
    12001 cacgaactgg atcgggctcg aactgctcgg cgaacgctac tggcggctca caccgatggc
    12061 ggcggacctc gcgggcggct acaccggccc cgcgctgttc ctggcccaac tggccgcgct
    12121 caccggcgtg tcccggtacg cggaggcggc ccgcgaagcg ctcgcgccgg ttccggggct
    12181 gctggacgcc ctgcacgggc gggccgacga actcggggcc ctgggctccg gcgcctacgc
    12241 gggactcggc ggaatcgcgt acgccctgac cgaggtgggc acgctgctgg gcgaccggga
    12301 agtgctggac ctggccggtc cggccgcccg gctgagctgt gcggcgaacg cggccgagga
    12361 cgggtacgga gtgcgcggcg gcgcggcggg cgggctcgtc tcgctgctcg cggtgtaccg
    12421 cgccaccggc cgcccgcagg cctggtgggg cgccgtgcgc tgcgccgagc ggctcgccgc
    12481 cgccccggcc cccgagaccg gaggcttcgc cgacggggcg gcggggatcg gctgggcgct
    12541 gctgcgcctc gccggggccg ggggcgacgc ccgtcaccgg agcgccgggc tgcacgccct
    12601 gcgccgggcg accgcgctga cggacgccgc gacggaccac ggacccgcct ggtgcgacgg
    12661 cgtggccggg gtcgcgctgg cgatcgccga cagccccgac gcgcgggagg acccggagct
    12721 gtccggctgg ctggcggcgc gctccggcga gctggcgggc atcgacccgc tcgccgacga
    12781 cagcctgtgc cacggggagt ccgggctgct cgaactcctc ggccacagcg ccctgcccgc
    12841 cctcctgccc ggcgtacggg ccgcgtgggt gcgccgggcc gggacgctgg tggccgcggc
    12901 ggaccgggcg gggccgctgt gcgggacgcc cggtcacgta ccgcacccgg ggctgctcac
    12961 cgggctctcg ggcatcgggc acgggctgct gcgggcgggg ttccccgacc ggatcggctc
    13021 cgccctgctc ctggacccct cccgggcccc ctgacccacc ccgaccttcc cgatgagacg
    13081 caccgttgct gatcaccaca ccaaccaaca gaggatgagg cagagatgaa gcagttcggc
    13141 gaatcggccc tgcaggcgtc cggcgacatc gcgcacgagg gcaccccgga gcacccggcc
    13201 gggcagatct ccctcgggtc caccggcgga ctcggtgcgc gcagcagact cctcagcgcc
    13261 gcggagggcg agagcggcta cagccacgac ctgccgtgga ccaccatgac gtccccgtgg
    13321 tgaccagatc cagccaactc tgcggcaatt gagccgaatt ggtccgctgc cgtgggagtt
    13381 gtcgctccag taatctgcgg ccatgcgagc cacttcgccg gtcatcgtcg ggcgggacga
    13441 ggagatcgga ctgctgagca gcgccctgga cgccgtgcaa cggcgttcgg ggcgcgcgct
    13501 gttcctcgtc ggggaagccg gtatcggcaa gtcccggctg gtgggtgagt gcgcctaccg
    13561 ggcctacggg ctcggcatgc cggtgctgcg cggccgggcc acctcgaccg ggctcgtcgt
    13621 gccgttccgc ccgctcgccg aggcgctggc gtcccggttc cgggcggccg gcaccccgac
    13681 cgacccggag ctcgcgccct accatccggc gctggcccgg ctggtcccgg agtggcgcag
    13741 ggccgggtcg cccggatacc cggagacggt cgtggagctg gcggaggcgc tgctgcggct
    13801 gctgtccgtg ctgggcaggg aggcgggctg cgcgatcctg ctggaggatc tgcacgactg
    13861 cgacacggag accgtcgcgg tcgtcgagta cgtcatcgac aacctcgccg atctccccat
    13921 cctgttcctg ggcaccctgc gcccggagcc gggcgccgcc ctggacctcg tacgctccgc
    13981 cgagcgccgg caggccgcga ccgtacggga tctcagcccg ctcgacgacg cccaggtgcg
    14041 ggcgctgacg ggcgcgtgtc tggagacggg gccgcgggag ataccggagg cggtgcacga
    14101 gcggctggcc gggcgcgccg cgggcaaccc ctacctgctg gaagtgctgc tggcggacct
    14161 cctcgacacc gggcggctca ggctgacgga cggcgcctgg gaggcggtgg agcagccggg
    14221 cgactccatc ccctcggaca tcgtgcgcag ttgggcccgc aggctggagc ggctcgacga
    14281 gccggtacgg gatctcttac tggcgtcggc caccctgggc agccagttct cggtgaccgt
    14341 gctccagacc gtcaccggct tcgaggaccg ggccctgttc acccatctgc ggtccgcggt
    14401 ggaggccggg gtcatcgccc cggacggcgc ggcgcccgac cgctacacct tccggcactc
    14461 gctcaccgcc gaggccctga tctcctcgct cgcgccggcc gaacgcgctt ccctggcccg
    14521 ccgggccgcc gcggccatcg agcagtccgg ggagccgctg gacgaggacg ggcggcagct
    14581 ggtggcctcg ctgcaactgg cggcgggcga ccgggccggg gccgcccgcc agttcgcgga
    14641 ggccggaaga cggatgctcg cttcgggagc gcacggctcc gccgtggtgc tgctggagcg
    14701 ggcgcacccc ctggccgccg agaccgaccg ggccgccgtc gccgagtcgt tggcggtcgc
    14761 ccgggccgag ggcggcgatc tggacggcgc gctggcgctc gcggacgcgc tgccgccggt
    14821 tccggcgcgt tccgaggccg ccgcccggcg cggccagatc cacatcgacc tcgcctgggc
    14881 ggcggtcatg gcggaacgca ccgcagaggc cgcgctccag gtcgaagcgg cccgcgtgct
    14941 gctcggtccg acaccgtccc cgggccgccg ggccgcgctc gtggtggtcg acggctatct
    15001 ggcgctgctc cccgggctcc ccgggcacgg gcggccgtac cgggatccgg tggagaccga
    15061 gcaggccgtc cagaaggccg ccgagaccgc cgaggccgag ggacttcccg tggtggcctg
    15121 ccaggcctgg cagttgctgg cgctgctgcg gcgcgaggag ggtttcgacg cggcggacgc
    15181 cgcactggaa cgaatgctgt cgatctccac cgaacacgcc ctgccggtct ggcgggtgga
    15241 ggcgctggtg cggctgggcg cgaacgcctt catgcggacc ggtgacgcgt cccggctgct
    15301 ctccgcccgg gcggcggcca ccgatctcgg cgcgctgctg ctgacccgta cggtcgacgg
    15361 actgctcgcg atgaacgcgg tgctgtgcgc ccggtgggag gaggcgcagg agatcatcga
    15421 ccgctcggcc gaggccagtg cccgggtcgg cgatctgtcc gcccaccgct atctgctact
    15481 ggccggggcg acgatggccg cgcaccgggg gcggcggcgg gacatggacc gggcgctggc
    15541 cgcgttccgg cgggccgggg gcgagcagtc actgctggtg ccgctgcggt cggggctctg
    15601 ccgggcgttc ggggcgctgc tggaggagga ccgggagcgg gcggcggcag gcctggacga
    15661 ggcgttggcc tgggagttgg accacccgag ctactactac ctgagcgggc ggtacgggct
    15721 gcgcccgctg ctgcgggtcc tggccgggca ggcggaccgg acggagctgg aggaggcgcg
    15781 ggcggctccc gggggctgcc tcgcgtggaa ccggcagttc ctggagctgg ccgacgcggt
    15841 gctgctgggc cggaaggggg acccggccgg ggccgcccgg atgatggcgt ccttcgcgca
    15901 gcgctccggg cccttcccgg tcgcccgcca tctggggctg cggctggtcg cggacgcggc
    15961 ccgggaggac ggctggggcg agccggtggc gtggctgcgg accgccgagg agttcttcta
    16021 cggggccggg gtgcagccgg tctccgccgc ctgccgggcg gcgctgcggc aggccggggc
    16081 gagcgtcggc cagcaccggg gcggctggga ccggatcccg tcaacgctgc ggaccagcgg
    16141 ggtgacgccg cgcgagtacg aggtgttcgt gctgctgccc gagcggcccg ggaaccagca
    16201 gatcgcccgc cggctgtcga tctcgccgcg cacggtggag aagcacatgg ccagcctgct
    16261 gaacaagacc ggccgcgcgg accgggcggc gctgtgcgag ttcgccgccg agtgcgccgc
    16321 cgagccggcc tgaggggcga ggagcagggc gtaccgcgta ccgcgaggcg gtgcgagcgt
    16381 acgggcatgg gggccggggc gggcaacatg ggggtgcctg gcggtttcgg tcgggtgccc
    16441 gggcggaaaa tgcgggcggg gccccgatgt gcggaggcgt gggcggcagc aggatcggcc
    16501 gtgcgtacgg tccagtccgc cgcccgtccc cctcccggag gcccgctgat gacccgacct
    16561 cccgtccgta ccggttccgc cggttccgcc ggtgccgccg gtgccgtgca cttctcgctg
    16621 ctcggcccgc tgaccgcccg gcgggacggc cgtgagctgc cgctcggccc gcgcaagcag
    16681 cgcctggtcc tcgccaccct gctggcccgg cccaacaccc cggtaccggt cgacgtgttg
    16741 accgacgcgg tgtggccgga cgatccgccc cgcaccgccc gcaagaacct ccaggtctac
    16801 atcagtgccg cccgcgccct cctgggcgcg gccggggacg gcggagcgga ccggctggtg
    16861 cacggctgcg ggggttatca cctgcgcatc gccgagggcg agctggacac gctgcgcttc
    16921 gggtcgctgg cccgggccgg gcgggcggcg gccgagcggg gcgatctgcc cggcgcggcc
    16981 cggttgctgc gcgaggcgct cgacctgtgg gaggggccgc cgctgcacga tctgcgggac
    17041 tcggccgggg tggccgatga ggcggaccgc ctggaggccc gatgtctgac ggtgtacgag
    17101 gactgggcgg aggccgagat cgagttgggc cgggccgccg tcgcggtgga cgggctgcgg
    17161 gatctggtgg agcgccaccc gctgcgggag cggctgcggg ccgcctggat gaactccctg
    17221 caccagtccg gccggcaggc cgaggcgctg gcggtgtacg acgactaccg gcagctgatg
    17281 gcacgggagt tgggtcttga gccgagtccg gcgatggcgg cgctgtaccg ctcgatgctc
    17341 ggccgggggc gggaggcgcg gcggcccgcc gtgtcccgcc ggacgccggc cccggtggtg
    17401 ctgcccgccg gtaccggggc gttcaccggc cgccgggagg agctccgggg cctgctcgac
    17461 gtgctgggcg gcggtgagga gcgcgtggtg gtcgtgtcgg gtccgggcgg ggcggggaag
    17521 tcggcgctgg cggtccgggc ggcgcacctg ctggccgacc cgttccccga cggccgggtc
    17581 catgtccggg tgcgccggga ggacgggacg gcgcgcggcc gggcggaggt cctggcggag
    17641 ctgggacggt ggtgtgggat cgcggaggcg cgcacggagt tccccgcgac ggcggcgggc
    17701 gccgaggtcc ccgcgacggc ggcaggcgtc gaggtgcccg agacggccgg ggccctcgcg
    17761 gtcctcgcgg aggcctggca ggagtggcag gcccggcacc gggccctggt ggtcctggac
    17821 gacgtgccgg acgaggcgtc cgtacggggg ctgctgcccc ggtcggggaa gtgcgccgta
    17881 ctggtcaccg cccgggggca gttgcccggt ctcgccccgg tgcaccggat cgcgctgccc
    17941 gcgccggcgg acggcgaggc gctggagctg ctggggaaac tgatcggggc cgggcggctg
    18001 cggacggacc cggcggcggc actgcggatc gtccgcgcct gcggggggct gccgctggcg
    18061 gtggaggtga gcgggatgcg gctggcggtg ctgcggcatc tgcctctggc ggagtacgcg
    18121 gaccggctcg acgacccgtc ggccgcgctc gacgaactgg tcgccggtga cgtctccgta
    18181 cggcaccgga tcgcgtccgg ctggcgggac ctggcggagc ccgaccggtg ggtgctgggg
    18241 cggctggccg ggctcgccga tgacgggtgc ttcaccctgg accgggccac ggtggcactg
    18301 ggctgcgggg agcgggcggc gatccgggcc gtggagtcgc tgatcgacgc cggtgcggtg
    18361 acctccccgg cgggcgaggt caccgcacat gccgcgctgt acgaagtgcc gcgcctgctc
    18421 tgcctgttcg cacgcgagca aacgacggcg ggcgagccgg ggacggctgc ggcgggcgaa
    18481 cagggggcgg cgggcgaccg gggcggtgcg cccgccgtcg ccctcagccc agggtgagca
    18541 gcttcagcag atcgtgcggc cggcgaccgt ggccgtcgcc cccgggggtg gcggccacgt
    18601 cggtgtccgc ccccgccagg aagtgcaggg cgagcagcag cccggccgcc ccggtggcca
    18661 ggtcggcgga gcagcgccgc agccgggccc cgggcaccag cagccggtcc ccgtcggcga
    18721 ccaggtgcca ggacaggttg cgcacggagg cgaggacctc gggcccggcc ggtccttcgt
    18781 cctccaactg gcgcgcggtg gcgacgagtc cggcgcgccc ggtgaacagc cccggctcgc
    18841 gcacgaactc gttgccgcag cccttgcgca ccccgggcag cagtccggcg agcgagggcg
    18901 cttcctgccg ggccaggtag gcgcgggcga ccagggcgaa gccgccgctg ccctggtcga
    18961 ggtagaggag gtggcggcgg ccgtccttga cctggaccgt gccgtcgtcc atcgccacgc
    19021 agtggccgga gtcccggtac agggcggtgc gggcggcgcg cagcagccac tcctcgccgg
    19081 tgagcgcgtg cagttcgagg tggagcagcg ccgcgccgct gagcccgcgc agcagcccgg
    19141 ccgacggcgg ggcctcgggc ccgcccgcca ccgtctcgcc ccgcaccagg cagtcgaggt
    19201 cccaggcggt gcgcagggcg gtgtccagca gctccgggtc cggggctccg gaggcggccc
    19261 cggccaggcg gacggcggcc agggcgatgc ccgcgcgccc ggtgagcaga tcggccgagg
    19321 tggacgggtg ggcggcctcg gcggctcggg cgaacagctc gcgcccctcg tccgggcggc
    19381 cgagcagagc cagtgtcacg gcggcgcccg gcagcccgtc gtagaggccg cccggggccg
    19441 cggggtcgcg gcggcgggcg gtctcggcga gccagtcggt ccaggccgcc gggaccgggg
    19501 ccccgacgcg gtggagggcg tagaggacac cggcggcccc gtgcgccaga tccgtaccgc
    19561 cggtggcgaa gcccttgggg tcgccgggga agagccggtc gcgccgctcg ggcgtggcgc
    19621 ccgcgtggat gcccgcgatc agccgggtcc gcagctcggc ccagtcgggg gtgggcccgc
    19681 cgaggagggc ggcgatctcg ctctcccggc cggcggcgcg ctccgccgcc cgcagcaggg
    19741 cggggcgggc cgggccggcg tcgggagcga gaccgtagcg ctcgcgggcc caggactcca
    19801 gggacagcgc cttgacccgg tcgtgggagg ccatctcggt cagcggcatc agcatggtga
    19861 gccaggtcgc ccacagggcg taggcgtcgg cctccgcgcc cggggtgccg ggcggggcct
    19921 ggagcccggg ggcaccggcc aacggggtcg tcccgtcgtc gagttcggtg gcgtactcga
    19981 agtcgacgag ggcgagccgg ccgtcgggcc gcaggatgat gttggagggg tgcagatcgc
    20041 cgaagcgcag ccctcggcca tggatctcgc gcagtgcgtc accgagttgg gcggtcacat
    20101 ggtgcaccca cgcggcgtag ggggcgagtt cgtcggccgt gcgggctccg cgcaccagcg
    20161 cgaagcgggc cacgatctcg tcgagcaggg tgggcccctc cacgtactcc gtcatcagga
    20221 accggtgctc ccacaccgtc cgtacgccgt acaccttcgg tacgcagtcg agcccggcga
    20281 gcgccgtgag ggcccggtgc tcgcgctcca gccgggtcac ggcgtcgtcg cccaccgcgt
    20341 cgagcccgca gtggggacgg gcctcgcgca ggacgacccg gtggccggtc tcccggtgcc
    20401 gggcgagata gatgccgccc gcgttggaga actggagcgc ctcggtgacg gtgtacggga
    20461 aggagtcgtc gcgggcggcg gcgcgggcgg cgaggtgggg ccgcagcagc tcgggcacct
    20521 tcacccaggc gggcgtccgg aacaccacgc cccgttcgtc gggcacgagt tcgccggagg
    20581 ggtggcgcag ggcgggcacc cgatcgcccc gggcgtcgcg gcaccagcgg tcgacgaagg
    20641 agccgtaccg tacgtagacg ggcgcgtcgc cgatgcgcag gtcgctcagg atgtacgggc
    20701 cccgccgtcc ggacagggcc gtggtcagct cgtcgagcag ccgggtcaaa gccgtctcgt
    20761 ccggcgggta gagggtgagg aacttccccg cgctgccccg ggacatgtac ttccccgaca
    20821 tcagcaggag cgcctgctcg ctgcggagga acttgaacgg gacccggtgc cgaaggcaga
    20881 tcgcggcggt gtcgcggagg gtgcgggccg cctcgtcggg aacggtcgac acgtggatct
    20941 tccagccctg ttcggccggt tcgccgtccg cgggcaggag ggacgtccac agcccgccgg
    21001 ccacgcgccg ccagccggag ggtggttcgg ccgtgtcgag ggggtagcgg gtctcctggt
    21061 cgggcagccg ggccggggtg tcgtagtacc ggcggtcggc gaggcagtac agctgggtct
    21121 cctggatgcc gggcacggca atacctcctc agagtgcgcc gggaccggcg gcgtcgggga
    21181 cggggcgggg tgcggcctcg tgcggggcgg gggcgccgga gtcctccgcg tcggcctccg
    21241 gcgcggcggg gttcgcgggc ggcgggacgg ccccggaccg tacggagggg gcgagcgtca
    21301 tgaccgccgc ggagacggcc agcaccgcgc cgacgacgcc gaaggcgttg cgcgggccga
    21361 gcgcggtcag cagcgcgcca cccgcgagcg ggccgaacgg ctggacgatc gaggacagga
    21421 aggaggccgc gctctgcacc cggccgaccc ggtcctcggg ggtgacgacc agcagggtcg
    21481 agaggaaccc gatgctggcg acggtcgaca ggcacatgca caccgcgcag agcagccccg
    21541 cgaccagcgg gctgctgagc caggccagga cgccggccgt cagcacgcag ctccagcagg
    21601 tgacgaccag gagggcccgg atgtgccggt cgggcgagag ccggggcgcg agcagcgcgc
    21661 cgacgagagc acccgccgag acgcaggtga tgacgaagcc gccgccgagc ccggagcggc
    21721 cgccctcgga gaacacggcg agggcggtga aggtgagggc gccgaacgcg aagttcatgc
    21781 cgaggccgaa gaccagcaac accgtacgga gatagggaag ttgccagagg aagccgagtc
    21841 cggcggtgag ctcgtcacgg ctgaggaccg agccggcctt cttgtgggcg gccgagcgcg
    21901 tacggacgag ggccacgcag acggtcgaca ggaacaggcc gaggaactgg gcggtgaagg
    21961 gcagcgcctc gtggacaccg aagagcgcgc cgccgacgag cgggccgacc agccggaccg
    22021 tggcggtacg cgcctggagc cgggcggtcg cctgacccat ctggtccggc ggcacgaccg
    22081 cgcgcagcag accgaaggcg gcgggggcgt agacgctgtt gaggacggcc ccggcggtgg
    22141 ccaccagcag gacgaggacc atgggggcgt ggccgttcca cacggcgacg gtcagggcgg
    22201 tgaccgcgag caggctcccc acgtcgcaca gccgcatcag ccggcggcgt tcgacccggt
    22261 cggccatgac cccgccgggc agcatcgtga tcagcacggc gcagatggag acggtcccca
    22321 cggtgccggc ctgcacggcg gagccggtct ccttgaggat gagcaggggc agcgcgaggg
    22381 cgctcatctg gctgcccaga acggcgaaca ggccgctcat ccagagcagc cggaagtccc
    22441 ggttggaacg gaggggcgtg gccatcggca ggctcccgga gatcggcata cggacgggga
    22501 cgggggcggg ggcgggggcg ggggcggggc gacgaggggc gagggacaag cgcggcgggg
    22561 cggctcccgt tgttcgcgga gccgccccgt accgcccgtc cgccggccgg gcgccgcggg
    22621 ggcgaggccg cggcctcggc ccgccgcggc gcacggcccg gtgggatcaa cgctcagttc
    22681 agcgctgctg ctcgacgacg ctcagcacgc tgatgcagtt gccgtcggtc gtgtcgccgc
    22741 cctggacgga cgtctcctgg aggtccagga cggagtgcgc ctcgacctcg ggggtctcgt
    22801 tggtctcgtc gccggccggc ttggtgttct cggacatggt gatctccatc cactnnnnnn
    22861 nnnnnnnnnn nnnnnnnnnc gtcactgcgg gaccgggacg cccggaggat gccctccggt
    22921 gtccggtgcg gcgggccggt gcctgccgtt gccgagaaag ttaggaagcc gggcctggcg
    22981 atcgcttcgc cgccggtatg gcaccggtat tgaccccagc tcgcggcggc gaaagcaccc
    23041 ccggtggggt gggcggacgc ccccggaacc cgtgctgacc tgtgcccata ccgctgccga
    23101 agcgccttcg gaccgtcctc gaaccggtgg cccacagcct gggtacgcgc ccgacgcgcc
    23161 ccggccccga aggaggcggc ccgcatggaa ctcgccgaac tcgtcgcacg gcggcccttc
    23221 cccgccgcag gtctgctgct cggcctcacc cggcgctgcc cgctgagctg cgcgcactgc
    23281 tcgaccgggt cgggcccgct cacccgccag cagccggacc ccgctcaact ggagcgattc
    23341 gtcggctcgt tcactgagga gaaccggccg gacgtggtca tgctcaccgg cggggagccg
    23401 ctgctcctgc ccgcgctcgc cgagcggctg agcaccctgg cacgggcgtc cggatcccgt
    23461 acggcgctgc tgagcggcat gttcttcgcg cggggctgga gccggcgggc cgggagccgg
    23521 cggggcgcag ggcgagcgcg cggacacggc acaccgggcc gtgggctcac gggcggacgg
    23581 ggcggggcgc ttccgcccgc catcctgcgc gccatccgct cggtcgacca tttctcggcc
    23641 tcgctcgacg tccaccacga acgcgaggtg tcgcgggccg acgtgttccg cgccctgcac
    23701 ctcgtccggg aggagggcgt ggccgtgagc ctccacctca ccgggacggg cggctcggac
    23761 ccgtatctcg ccggcctcac ccgggcggtg gaggaggagt tcgacggccg ggtgccgtgc
    23821 ctggtcaacg aggtgcggcc gttcggccgg gccgcttcct gggcacgggc cacccgcacc
    23881 ggacccgacc ccgccgcggc gtctccgtgc tcgatggccg cctggccggt ggtcgccttc
    23941 gacggccggg tgctggcctg ctgcaaccag gacaccgtgg accgccggcc cgccccggcc
    24001 catctcgacc tcggccacat cgcggaggac gactgggcga ccgtgcgccg cagggcgctg
    24061 gagtccccga tgctgcgcat gctccgcacg gtcgggccgg cgcatctggc cgcccggtac
    24121 ggttccggcc cccggccggg ctcctactgc gacggctgcc gggcgctggg cggcgacgag
    24181 gcggtggccg ccggggcgcg gtcggtggcg ggcggtgcgg ccggggcgct gctggatctg
    24241 acggccgcga tgcggggttc ccgggagggg gcgcagggcg tcgtgcgccg ccacggctgc
    24301 gcggagtacg cgccgctggt cgtcacgggc gagccggccc ggccggagac cgacggacgg
    24361 gacctccgat gagcacgggc gccgccgccc ggcttccgat gagcaccggg gcctccgccc
    24421 ggctgcggac caaactcctg ctgctggagc cggagttccg tggcgcgacg caccacatgt
    24481 ggcgcgccga ggggctgttg ccgcgctacc ggacgtatct gtgcaccatg cacgccgtca
    24541 tccgggcctc cgtcccgctg atggagctgg ccctcgaccg cctccgcccc cgggccgcct
    24601 ccggtgatcc gctcgcggcg ccgctcgccg cgtatctggc ggagcacatc cgggaggagg
    24661 agggccacga ctcctggctg ctggaggacc tccgggcggc gggcgggacg cccgaggacg
    24721 cgctcggccc gctgccctcc cccctgaccg cctcgctcgt cgggtcccag tactactgga
    24781 tcgagcacca ccacccggtg gccctgctcg gctacatcgc cgtactggag ggctacgcgc
    24841 ccgcccccgg cctgaccgac cgcatcgccc ggcgcaccgg gctgcccgcc gccgccctgc
    24901 ggaccgtacg ggagcactcg gtgctcgaca cggagcacct cgacgagctc tacgccctgc
    24961 tggaccggct gccgctcggc cgggaccggg aagcggctgt ggcggtcagc gccctgcact
    25021 ccctcgacgc gctcacccgg ctgttcgtcc ggctcgggcg ctccgcgccg gcgccgtcgc
    25081 cgcggggagc cggacctgtc tcaccgatgg gagtcacatc atgaccggac cacccgggaa
    25141 cggcgaacgg ccgccgctgc ccgacgcgtt gtacgaggcg ggcttccccg tcgacctgct
    25201 caccgaggag caggtcgagg tgctgagcgg cctgacgccg gaggaactga cgctgctgct
    25261 cgatgtgaag agccggctgg acgccgtggg gccggaggtc caggcgcacg gcgagatcgc
    25321 cgggggcgca ctgttctgac cccggcccgg ccccgacccg acccggttgc ggccggccgg
    25381 cggtacgggc ccggcggcgg cgatcgcacc cgccgccggg cccgtacccg cccgacatcc
    25441 cggaccgcca accattcttg gggacccgcc atgaactgcc tctcgtgcca gcaggatctg
    25501 ccgccgacgg cccggttctg ctcgtcctgc gggacgccgt gcgcgaccgc ctcggctgcc
    25561 gctcccgccg ctgtcaccgc ggccggaccg gctgccgcca ctcccccgcc gagtgacgaa
    25621 cgcaagccgg tgaccgtgct gttctgcgat ctcgtcgggt ccaccgcgct gtccggcgtg
    25681 ctcgacccgg agacgctgcg cacggtgacc ctgcggtact tcgaggcgat gagcgcggag
    25741 atcgtggcgc gcggcggcac cccggagaag ttcatcgggg acgcggtgat ggcggtgttc
    25801 ggcgtcccgg tggtccggga cgacgacgcc cgccgggcgc tggcggcggc gctcgggatg
    25861 cgccgggcgc tggcccggct gaacgaggag ctggccgcca ccctcggcat cgagctggcc
    25921 attcggatcg gcgtcaacac aggtcaggtg gtggcgggtt cggaccggac cgcccggcag
    25981 gcgctggtct ccggggagac cgtgaacatc gccgcccggc tggaacagaa cgccggccgg
    26041 ggcgagatcc tgatcggccc cgggaccctg ctcgccgccg gtccgacggt gagcgccgag
    26101 cccaccgggc cgctgcggct caagggcaag cgggacagcg tcgaggccca ccggctgctc
    26161 gcgctgggcg cggacgaccc cgagctgctg cgccgcttcg acgtcccctt cgtcgggcgc
    26221 gacaccgagc ggcgggtgct ggacgccgcg ctggagggga cggtgcgcga gggcacggcc
    26281 ggactgctgc gggtcaccgg ggaggcgggg atcggaaaga cccggctggt acgggagtgg
    26341 ctggcggggc ggtcggcgtc cggcgggctc gcgtacgggg cagggcggtg ccgcagttac
    26401 ggggaccacg gcaccctcgc gccgctggcc gacgcggtgc gttccctgct ggccgcgagg
    26461 gagtccccgg aaggcgcgca ggaggctgcc gacgggccag cggtcgacgg gtcggcggtc
    26521 ggcgggctgg cggtcggcgg gctggcggtc ggcgacgcga tggctctgct gtccgggggt
    26581 ctgctgcgtg acggtacgcc gaacgcgccc ttcgaggaca tgtgcgcggc cctggcgacg
    26641 gtcctggaac gggcggcccg ggtccgcccg gtcgtcctgg tgctggacga ctggcacgcg
    26701 gcggccccgc tgctggtccg cacggcgcac cggctgacgg acggctcggg gtgcgcgggc
    26761 gtgctggtgc tctgcgccgg acggccggac gggccggagg ggccggaggg gccggacgac
    26821 ggcgacggtc cgcccgccgg tgcgggggcg ttgctccagc tcacggggtt gccgtacgag
    26881 gaggcggcga ggctcgccgc cgtactcgcc ggtccggacg gcggggcccc cggcaccgac
    26941 cggctcctgg agcgggccgg gggcaacccg ctctatctgg aacagctcct ggtcggcgac
    27001 cgggcggacg ccgggggcgg agtgaacgcg ccggtcgggt cgggcggggc ggccggcgag
    27061 gaactgccgc cgacgctcca ggcgttgctg ggcgcgcgga tcggtgcgct ggcccgggcg
    27121 gagcgcgacg tggtggacct ggccgccgtg atcggccggg agttcaccgc accggaactg
    27181 gtccggctcc agtcgtccgt ccgggccgcg gagggccacg gagcctcagc gcgacgacag
    27241 ctggtggacg aggcgttgga ggcgctgggc cgccggcgac tggtcgagtc gggcccgccg
    27301 ggagaccggg cggcggcgga ggcgtaccgg ttcagcagcg gactggtgca cgaggtcgcg
    27361 tacgcctcgc tgtccaaacg agccaaggcc gaacgccacg cctgggcagc cgagttgccc
    27421 agtgtgctgc gcagcggcga cggcgcggtc ggcggccatc tggagcgggc ctaccgctac
    27481 cgggcggagc tgggcctgct ggacgaccgg gcccgtcggc tgcgcgaccg ggccgccgcc
    27541 gcgctgggcc gggccggggc gcaggccgcc gcccggtccg acctgcactg ggcgcacggc
    27601 ctgctggagc gggcggtgga gctgagcccc ggcgacccgg cggcgacgcg gcggctcggc
    27661 gaggtgcggg tggcgctcgg ccgcgccgcg gagggcgccg aactgctgct ccgggtacgg
    27721 gacggggcgg ccgacccggt ggaggccgcg cacgcccgcc tcgcgctcgc ggtgctggac
    27781 ccgggcggcc ccggccccgc cgccgtggcc cgtaccgtgc ttccggtgtt cgaagcggcc
    27841 ggggactcgg tcggccgggc acgcgcccat ctgcggctcg cccagcagtt ccagcggtcc
    27901 gggcggcacg aggaggcgga gcgggaccag gcgcgggccc tggagcacgc cgtgctggcc
    27961 ggcgcggagc cggaacgggc cggggcgctc ggcgcgatcg gcatctccct gtggcgcggg
    28021 ccggtcccgg tgcccgccgc ggtgatccgc tgccggacgc tgctggcggc gcacggcgcg
    28081 ggccgcccca cggtccgggt cacgctcaac tgccccctgg cggtgctgta cgcgctccag
    28141 gacgcggccg atgacgcgta cggctgcctg gccgaggcgg agcggctggc cgggaagctg
    28201 gggttcgctg aggcggaggt cttcctgccg atgttccggg cgacggtgga ggcgctgtcc
    28261 ggccggagcg ccgccgcgct ggacctgctc ggccgggcgg acgcggcggc ccggcgcacg
    28321 ggggcggccg ggatgcggac ggcggtggcg ctggacgcgg cccgcctgga gctggacgag
    28381 ggccgggagg accgggcggc ggagcggctg gcgggcgtcg gcgacgcttc ggggctgagc
    28441 cgggcggacg cggtggacct ggcggggctg cgggcccggc tgacggcgcg ggaccggccc
    28501 gaggaggcgg ccgggtgggc ggagcaggcg gtacgggcct cactgctcac cgattccccg
    28561 ctggtgcagg cgacggccga gctggaccgg gcgcacacgc tcgccgcgct gggccggcac
    28621 ccggaggccg gggcagccgc ccgggcggcc ggggcgcact tcacgggcaa ggggcaccgg
    28681 ccgggggtgc gccgggtctc cgggttcctc gcgcgcccgc ccctgccgat ggccacgacg
    28741 agggagagga gctgaccgat gaccaccacg gaaccagcac gagcaccggc acagacagca
    28801 gcggcagcgg cagcggcagc ggcagcggca cagacgcaga cacaggcgga atcggtgcgg
    28861 ccccgggcgc gtacggcccc ggggcagggc ctgacctgga gtctgcgcgg gcgcggcccc
    28921 gacgacgtac cggtgctggc ggacgccggg ccgccgctcg gccgccccgc cgggcccgcc
    28981 accgggcgcg gcgtccgcgt gtgcgtcgtg gactcgggcg tggagcgcga ccacccgctg
    29041 gtcggcccgt tggccggctc ctgggtggtc gtcaaggacg gggagagcgg cgggatcacc
    29101 gtcgagccga ccacgaccgg cgacacctgc ggccacggca ccgcgtgcgc gggcatcatc
    29161 cgccggaccg ccccggagtg cgagatccac agtgtgcggg tgctcgggga gcggttctcc
    29221 ggcaccggcg acatcctgat ggccgggctg cgctgggcgg tggagcagcg gttcgacgtg
    29281 gtcaacctca gcctgtcgac gacccgtacc cggttcgcgc aggagttgca cagcctggcc
    29341 gacagcgcct acttcgcccg tacggtgatc gtcgcctcgg cgcacaacac cccggtggag
    29401 agcttcccct ggcggttcgc ctccgtgatc tcggtgggca gccaccagga ggacgacccc
    29461 gaactgcacc tgtacaaccc cgagcccccg gtggagttct tcggaccggg ccagaacgtg
    29521 accgtgccct ggctgggcgg ccggacgatc cgcaccacgg ggaacagctt cgccacgccg
    29581 tacgtcgccg ggctctgcgc ccgcgtgctg tccgcgcatc cgcggatgac ggccttccag
    29641 ctcaagaacg ccctctatct gtccgcggcc aacgtgcgcc acgcgccgcg tccttcttcc
    29701 cctccggcag gagatacagg agatacccgt gatgactcag agaactgatt ccgccctgtc
    29761 ccccgtctct cccacctctc ccgtcatcga cgcgccgcgc agcgagctgc tccagtcggt
    29821 cgtcgacgtg gcccgtgcca tcttcggggc cgaggccagt tcggtgttcc tgctcgacga
    29881 ggaggcggac gagctggtct tccaggccgt gtccgggcag ggcgaggagt tcctggtggg
    29941 ccgccggttc ccggccgggc gcgggatcgc cggctgggtg gcgacctccg gcgagccgat
    30001 ggtcgtcgac gacctgagcg ccgacccgtc cttcgaccgc tcgctggcgg agtcgactgc
    30061 gtacgtaccg aacgccctga tggcggcccc gctcatcagc gacgcccgga tcctgggcgt
    30121 cctggaggtg ctggacccgt ccccgcaggc ccggtcgggg gtacgggagc tggacctgct
    30181 cgcgatgttc gcccggcagg ccgccgccgc cctgcgggtg atcaccccgg agcgggtacg
    30241 ggatgccgag gagcaccccg tcctggccgg gcccacgctg gcgggcgcgc aacgcgagga
    30301 cgcgctgaag ctgctgggta gcctggaacg gctgctgcgc ggcgtcggct gaggcggccg
    30361 acacccggga gtagccacgg gcccggcggg caggagcggg gcgtcggcac aagggcacca
    30421 gcccggacgg agtgcacagg gcacggcccg cacagggcac ggcccgcaca gggcacggcc
    30481 cgcacagggc acagagcgca gggcacagcc cgcacaatgc acagggcacg gagcacaagg
    30541 gaaggaccac acgatgaagc tcgctttctc caccctcggg gtgccgggga cgccggtcgc
    30601 cgaggtcgtc cggctcgccg ccggtaacgg ctaccagggg gtggagctgc gcgtccatcc
    30661 ggaggagccc gtgcacctgg ggctctcgtc gctggaacgg gccgacgtgg tcgaggcgtt
    30721 caaggccggc ggggtggaga tcctggccct cgccgggtac gtccgggtgg ccgccgaggg
    30781 ggacgacgag ccggtcctcg cggagctgtc cgagctggtg aagctcgccc gggacctggg
    30841 cgcgtcctac gtccgggtct tccccggcgg cggcgaccag gagcaggcgg aggccgacgc
    30901 gacggccgcc cggcggctcg gcgcggcggc cccggccgcc gccgacatgg gtgtgagcat
    30961 cctgctggag acccatgact cgcaccgtgc gggcctcgac gtcgcccggg tcgtcgccac
    31021 ggtcgggcac ccccgggtcg gcgcgatctg ggacgtcctg cacacctggc tcgccggtga
    31081 ggagcctgcc gccggccggg cggtgctggc cccgcacctg ggctacgtgc aggtga
//
