LOCUS       NZ_KZ679082            21077 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Streptomyces sp. CS149 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ679082
VERSION     NZ_KZ679082.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS149
  ORGANISM  Streptomyces sp. CS149
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7754255)
  AUTHORS   Malmierca,M.G., Perez-Victoria,I., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Cooperative Involvement of Glycosyltransferases in the Transfer of
            Amino Sugars during the Biosynthesis of the Macrolactam Sipanmycin
            by Streptomyces sp. Strain CS149
  JOURNAL   Appl Environ Microbiol 84 (18), e01462-18 (2018)
   PUBMED   30006405
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7754255)
  AUTHORS   Olano,C., Malmierca,M.G., Mendez,C. and Salas,J.A.
  TITLE     Characterization of the biosynthesis gene cluster for the
            macrolactam sipanmycins: involvement of four glycosyltransferases in
            the transfer of two aminosugars
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7754255)
  AUTHORS   Olano,C., Malmierca,M.G., Mendez,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAR-2018) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 556.87x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 11:43:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,915
            CDSs (total)                      :: 6,834
            Genes (coding)                    :: 6,691
            CDSs (with protein)               :: 6,691
            Genes (RNA)                       :: 81
            rRNAs                             :: 12, 7 (16S, 23S)
            complete rRNAs                    :: 12, 7 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 52 of 144
            Pseudo Genes (incomplete)         :: 108 of 144
            Pseudo Genes (internal stop)      :: 12 of 144
            Pseudo Genes (multiple problems)  :: 27 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:40:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1042297
            Orig. end                         :: 1063374
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ679082.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Professor JA Salas
            laboratory.
FEATURES             Location/Qualifiers
     region          1..21077
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21077
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21077
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11077](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11077
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(283..296)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
     misc_feature    complement(964..977)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            complement(1271..2479)
                     /locus_tag="C6W96_RS04615"
                     /old_locus_tag="C6W96_04605"
     CDS             complement(1271..2479)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070136.1"
                     /locus_tag="C6W96_RS04615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04605"
                     /product="glycoside hydrolase family 6 protein"
                     /protein_id="WP_107410567.1"
                     /transl_table=11
                     /translation="MPGTRVRRRTAHRERRRAARRHALLAVASAVVAIGATAGLIDVGH
                     QDGRDTARPEPTAPPVLQPLPAVPTPTPTAPAPSASSARPAPAPSPSRTTARPSAVPEL
                     PPSPSATPAPAPRARLFRHPDSQVLDWVRAHPDDPRRPVIESRIAERPAAVWFAAHNPG
                     EIAGQVREVTRGAAAAGRIPVLVPYAIPDRDCGGASKGGAPDLAAYDAWIRQFAEGLGA
                     GAAIVILEPDAIALSDCLSASDRAARFASLARAGRTLRTANPRARVYFDGGHSGWHAPA
                     KQAAALRAAGAATNGDGIFTNVANFHRTADERAYARRVLAALGGPAGLGAVVDTSRNGN
                     GAPPAGQWCDPAGRALGQTPTTRTGEARIDAYLWVKLPGESDGCSGAAGSFTPEYAYAL
                     ATG"
     misc_feature    2577..2590
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            2577..3287
                     /locus_tag="C6W96_RS04620"
                     /old_locus_tag="C6W96_04610"
     CDS             2577..3287
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123149.1"
                     /locus_tag="C6W96_RS04620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04610"
                     /product="DUF5995 family protein"
                     /protein_id="WP_107410568.1"
                     /transl_table=11
                     /translation="MTQIEQSAVPAQGGGPPTGGFPVIERMRELRSRWPYEDGVAVFNR
                     VYLEALETAGPELGRGGHDGREAAALLGVRCAERYLSAAETATAGGRPPECWRPLLPCR
                     RHPGVRPLQFALSGLQAHVGHDLVLAVVDTCRTLGCDPPDLEGEFERVGDLLALLEERI
                     HDELMPGPDLLGIADPLTHLVSSWSLERAREAAWSAARTLWRLREFPPLAEEFRKRTDA
                     GAGLVGRLLLTPCR"
     gene            complement(3313..5007)
                     /locus_tag="C6W96_RS04625"
                     /old_locus_tag="C6W96_04615"
     CDS             complement(3313..5007)
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671499.1"
                     /locus_tag="C6W96_RS04625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04615"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_107410569.1"
                     /transl_table=11
                     /translation="MTSTVPNAVQHTDAAAPPITMFGPDFPYAYDDFLAHPAGLGQIPA
                     TEHGQEVAVIGGGLSGIIAAYELMKMGLKPVVYEADRIGGRLRTVGFDGCDGDLTAEMG
                     AMRFPPSSTALQHYIDLVGLQTRPFPNPLSPATPSTVVDLKGESHYAETIDDLPQVYRD
                     VAEAWNACLEEGADFSDMNRALRERDVPRIREIWSQLVERLDNQTFYGFLCESEAFKSF
                     RHREIFGQVGFGTGGWDTDFPNSILEILRVVYTEADDHHRGIVGGSQQLPLRLWDREPQ
                     KIVHWPLGTSLSSLHDGEPRGAVTRLTRTAGNRITVTDATGDIRTFRAAVFTGQSWLLL
                     SKIDCDDALFPIDHWTAMERTHYMESSKLFVPVDRPFWLDKDETTGRDTMSMTLTDRMT
                     RGTYLLDDGPDKPAVICLSYTWCDDSLKWLPLSPKERMEVMLKSLGEIYPNVDIRSHII
                     GNPVTVSWENEPWFMGAFKANLPGHYRYQRRLFTHFMQDRLPEDKRGIFLAGDDISWTA
                     GWAEGAVQTALNAVWGVMHQFGGATDATNPGPGDVFDEIAPVELPED"
     gene            complement(5057..5854)
                     /locus_tag="C6W96_RS04630"
                     /old_locus_tag="C6W96_04620"
     CDS             complement(5057..5854)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453202.1"
                     /locus_tag="C6W96_RS04630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04620"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_107410570.1"
                     /transl_table=11
                     /translation="MPSLRTALLQSSGRPGAVAENLKALDEAAARAAGAGARLLVAPEL
                     FLTGYAIGDAVPVLAEPADGPGAQAVAEIAVRHGLAVLYGYPERDGERIFNASRLIGAD
                     GVRLANYRKTHLFGCFEQEWFTPGEQTVVQADLDGIRIGLLICYDVEFPENVRAHALAG
                     TDLLLVPTAQMHPFQFVAESVVPVRAFESQMYVAYVNRTGPEGEFEFVGLSCLAGPDGV
                     VRTRAGRGEELVFGEVDPEFLAASRAANPYLADRRPGLYGSLA"
     gene            complement(6039..6497)
                     /locus_tag="C6W96_RS04635"
                     /old_locus_tag="C6W96_04625"
     CDS             complement(6039..6497)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512479.1"
                     /locus_tag="C6W96_RS04635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04625"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_030589514.1"
                     /transl_table=11
                     /translation="MRLNDLDERIVHALAEDARRSYADIGAIVGLSAPAVKRRVDRLRA
                     EGAITGFTVRVDPAALGWETEGFIEIYCSRNTSPDAIKQGLARYPEIASASTVTGEADA
                     VVQVFAADMRHFEQVLERIAGEPYVERTKSVLVLSPLLRRYSAEAPPV"
     misc_feature    6464..6478
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.1"
                     /tool="antismash"
     gene            complement(6614..8071)
                     /locus_tag="C6W96_RS04640"
                     /old_locus_tag="C6W96_04630"
     CDS             complement(6614..8071)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015607337.1"
                     /locus_tag="C6W96_RS04640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04630"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_107410571.1"
                     /sec_met_domain="Aldedh (E-value: 7.7e-157, bitscore:
                     521.1, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFFTDLAHQYIDGEWRPGKGSWDIIDFNPFDGEKLASIPVATAD
                     EVDQAYRAAERAQQAWADTNPYSRRAVLEKALRIVEEREPEIAEAIVAELGGTRLKAGF
                     ELHLAKEFLREAIQLALRPAGQILPSPSEGKENRVYRVPVGVVGVISPFNFPFLLSLKS
                     VAPALALGNAVVLKPHQNTPICGGTLLAKVFEDAGLPAGLLNVVITDIAEIGDTLLEHP
                     VPQVISFTGSDKVGRHVATVCAQNLKRAVLELGGNSALIVLDDADVDYAVDAAVFSRYI
                     HQGQVCMAANRILVDRAVEAEFTEKFVAKVASLTVGDPADPATQIGPLINSSQAESVSK
                     LVDQTVAAGATALLHGRADGNLVSPSVLTGLAADSPVLHQEIFGPVALLIPFDGEDEAV
                     RIANDTPYGLSGAVHTGNIERGVRVGQRIHTGMIHINDGTVHDEPIVPFGGEKSSGLGR
                     LNGDSMIEAFTTQKWISIQHGRSLFPF"
     misc_feature    complement(8112..8125)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.08"
                     /tool="antismash"
     gene            complement(8237..9703)
                     /locus_tag="C6W96_RS04645"
                     /old_locus_tag="C6W96_04635"
     CDS             complement(8237..9703)
                     /GO_function="GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960551.1"
                     /locus_tag="C6W96_RS04645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04635"
                     /product="GuaB1 family IMP dehydrogenase-related protein"
                     /protein_id="WP_006123154.1"
                     /transl_table=11
                     /translation="MRFLEPGTGRYTESPAVPYDLTYDDVFMVPGRSAVGSRQGVDLSS
                     PDGTGTTIPLVVANMTAIAGRRMAETVARRGGLVVIPQDIPIEVVTDVISWVKTRHLVL
                     DTPIELAPGQTVADALSLLPKRAHGAGVVVDADRRPVGVVTEHDLSGVDRFTQLSEVMS
                     KDLVLLDADIDPRDAFNKLDGANRKLAPAVDADGRLVGILTRKAALRATLYTPATDAEG
                     KLRIAAAVGINGDVAGKAKQLLDAGADVLVVDTAHGHQESMISAVKAVRALDPQVPIVA
                     GNIVAAEGVRDLIEAGADIIKVGVGPGAMCTTRMMTGVGRPQFSAVLECAAEARKHGKH
                     VWADGGVRHPRDVAMALAAGASNVMIGSWFAGTYESPGDLQQSADGRFYKESFGMASAR
                     AVKNRTSDESAYDRARKALFEEGISTSRMFLDPARPGVEDLIDSIIAGVRSSCTYAGAG
                     SLAEFAEKAVVGVQSAAGYAEGKPLHASWS"
     misc_feature    9694..9705
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.23"
                     /tool="antismash"
     misc_feature    9703..9717
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.62"
                     /tool="antismash"
     misc_feature    9710..9719
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    9711..9724
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.76"
                     /tool="antismash"
     misc_feature    complement(9712..9725)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.18"
                     /tool="antismash"
     misc_feature    9713..9726
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    9714..9727
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.7"
                     /tool="antismash"
     gene            10001..11077
                     /locus_tag="C6W96_RS04650"
                     /old_locus_tag="C6W96_04640"
     CDS             10001..11077
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960550.1"
                     /locus_tag="C6W96_RS04650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04640"
                     /product="terpene cyclase"
                     /protein_id="WP_107410572.1"
                     /sec_met_domain="T1TS (E-value: 2.2e-87, bitscore: 292.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSELPDIYCPFPQRTNPHVAHTRGHLDAWTRATGLVHRESARNR
                     FEQADFGAFVGMVYPTADEENLDLVADWFVWLFLVDDQLDDGHLGRSPDRVRSVVERMR
                     AVVDGSAPEPLPGEEVPAAVTALADLWKRTTPNAAPHWRTRFAWHLVTYLTTATTWEAG
                     NRAEDVVPSEDTYIAKRRHTGAIHVCMDLIEIVAGIEAPESLHNDPRFITALEAACNHV
                     CWANDVYSFEKEQVLGEIHNLVHLVRHHRGLGEQQALDHVAERLAMETERFLTAEDELL
                     ELYPELSGLLVPYLDGMRSWMRGNLDWSRQTPRYNPADVGQYEEPEEYLEETVLGIPPA
                     RTEAAAPAPCAAKAPPAG"
     gene            complement(11143..12138)
                     /locus_tag="C6W96_RS04655"
                     /old_locus_tag="C6W96_04645"
     CDS             complement(11143..12138)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490194.1"
                     /locus_tag="C6W96_RS04655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04645"
                     /product="sugar-binding domain-containing protein"
                     /protein_id="WP_030589527.1"
                     /transl_table=11
                     /translation="MRMGPAELVQAAAMARRFYLEGKSKIQIAEEFGVSRFKVARVLET
                     ALERDLVRIEIRVPAELDAERSDALRARYGLRHAVVVESPAEEQDDAPDPENLGEVAAD
                     LLGELVAEGDVLGLAWGRSTIHMAAALDRLPPCTVVQLTGVYDAGTAERGSVEAVRRAA
                     QVSGGEAHPIYAPMLLPDPATAAALREQTGIARAFEYFDKVTVAAVSIGSWEPGISTVH
                     DMLSDEERAHYASLGVAAEMSAHLFDAEGRRVGRDLGERCITVEADRLRRIPEVVAIAG
                     GQRKAAAIGAVLRSGLVTSLVTDTAAADYLLTESAAGVRPALERADPDGE"
     gene            complement(12272..12955)
                     /gene="rpe"
                     /locus_tag="C6W96_RS04660"
                     /old_locus_tag="C6W96_04650"
     CDS             complement(12272..12955)
                     /EC_number="5.1.3.1"
                     /GO_function="GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rpe"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044795.1"
                     /locus_tag="C6W96_RS04660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04650"
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="WP_010057358.1"
                     /transl_table=11
                     /translation="MAQINPSILSADFARLAEEAKAVEGADWLHVDVMDNHFVPNLTLG
                     VPIVEALSKATDTPLDCHLMIEDADRWAPQYVEAGAGSVTFHAEAAAAPVRLAREIRAK
                     GARASMALKPATPIEPYEDLLPELDMLLIMTVEPGFGGQAFLDIMLPKIRRTRELISKH
                     GLELWLQVDGGVSAATIERCAEAGADVFVAGSAVYGAADPAAAVRDLRALADVATAAAP
                     WACDH"
     misc_feature    complement(12942..12955)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     misc_feature    13040..13052
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.37"
                     /tool="antismash"
     misc_feature    complement(13043..13063)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 23.43"
                     /tool="antismash"
     gene            complement(13104..14537)
                     /locus_tag="C6W96_RS04665"
                     /old_locus_tag="C6W96_04655"
     CDS             complement(13104..14537)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512473.1"
                     /locus_tag="C6W96_RS04665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04655"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_032780955.1"
                     /transl_table=11
                     /translation="MNDQPRRRPAKPHRRPKKDPVRFLAFEALRAVDERDAYANLVLPP
                     LLKKARAKGDFDGRDAALATELVYGTLRRQGTYDAIVAACIDRPLREVDPPVLDVLNMG
                     VHQLLGTRIPTHAAVSASVELARVVLGEGRAKFVNAVLRKVTAHDLDGWVEKVAPPYDE
                     DAEDHLAVVHSHPRWIVSALWDALGGGRAGIEDLLEADNERPEVTLVARPGRSTTEELV
                     KALGEDNSLPGRWSPYAVRMAEGGEPGALEAVRESRAGVQDEGSQLVAAALAAVPVEGR
                     DSRWLDGCAGPGGKAALLAALAAERGATLLAAEKQPHRARLVERALAGNPGPYQVITAD
                     GTRPPWLPGTFDRILMDVPCSGLGALRRRPESRWRRRAEDLEAFAPLQRGLLREALKAV
                     RVGGVVGYATCSPHLAETRVVVEDVLKGRGGEPVEAEWIDARPLLPGVPALGEGPDVQL
                     WPHLHGTDAMYLALLRRTG"
     gene            complement(14642..15574)
                     /gene="fmt"
                     /locus_tag="C6W96_RS04670"
                     /old_locus_tag="C6W96_04660"
     CDS             complement(14642..15574)
                     /EC_number="2.1.2.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fmt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490197.1"
                     /locus_tag="C6W96_RS04670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04660"
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="WP_107410573.1"
                     /transl_table=11
                     /translation="MKLVFAGTPEVAVPALDALIASDRHEVAAVVTRPDAPAGRGRRLV
                     ASPVAERAEEAGIEVLKPVRPRDEEFLARLREIAPDCCPVVAYGALLPKVALDVPARGW
                     VNLHFSLLPAWRGAAPVQHSLMAGDEVTGASTFLIEEGLDSGPVYGVLTEEIRPTDTSG
                     DLLTRLAFAGAGLLAATMDGIEDDTLHAVPQPHEGVTLAPKITVEDAQVQWSAPALRVD
                     RVIRGCTPAPGAWTLFRGERLKLIQATPVLDRTDLAPGELSAAKNNVYVGTGSHAVELL
                     WVQPQGKKPMRAADWARGVRIAHGELLGS"
     misc_feature    complement(15559..15573)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.72"
                     /tool="antismash"
     misc_feature    15621..15637
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.87"
                     /tool="antismash"
     gene            15887..16453
                     /locus_tag="C6W96_RS04675"
                     /old_locus_tag="C6W96_04665"
     CDS             15887..16453
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010057355.1"
                     /locus_tag="C6W96_RS04675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04665"
                     /product="hypothetical protein"
                     /protein_id="WP_032768303.1"
                     /transl_table=11
                     /translation="MADHATHDAQARASLHLLVRDIERVRRQVDALRTLTAQLGNVYRP
                     RRSGPSAGFVVYGRAPAPTVRLAQELRDSVETLVTAAVDFDRSLGFSWDAVGSALGVTK
                     QAVHRRYGTRRATPQPAAETGGENTAVPRPVSVGTGLTGSSAKGSGSPVPTVPAARSMP
                     PQPSAAPQPAREELRPGAFPGPRNG"
     gene            complement(16577..18721)
                     /locus_tag="C6W96_RS04680"
                     /old_locus_tag="C6W96_04670"
     CDS             complement(16577..18721)
                     /EC_number="3.6.1.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044799.1"
                     /locus_tag="C6W96_RS04680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04670"
                     /product="primosomal protein N'"
                     /protein_id="WP_107410574.1"
                     /transl_table=11
                     /translation="MSSENEQSAEPGAGPPEQLALIRETVRRAKVPRAKPRTWRGAPLA
                     DELPVARVLVNKGVLHLDQYFDYAVPQELDTDAQPGVRVRVRFGAGGRNVQGGRREGGG
                     LIDGFIVERRADSDYQGALAALASVVSPEPVLGPELLALCRAVADRYAGSLADVLQLAV
                     PPRNGRAEAKPSPDPLPPPPPPDPGTWERYGQGPAFLRALAEGGAPRAVWTALPGPHWP
                     AEIAGAVAATLSSGRGALVVVPDGRAAARVDAALTEALGAGRHALLTAESGPEKRYRQW
                     LAVRRGSVRAVVGTRAAMFAPVRDLGLVVVWDDGDSSHSDDNAPFPHVREVLELRSAQG
                     RCGFLLGGTSCTVEAAQLVESGWALPLLADRERLRRAAPLIRTVGDGELARDGAARSAR
                     LPSLAWGAVRDGLRTGPVLIQVPRRGYAPRLACERCRTPARCRHCAGPLEAPDQQDLNC
                     AWCGRAERAWSCAECGSTRLRARIVGARRTAEELGRAFPAVPVRTSGRDHILDAVPDAP
                     ALVVSTPGAEPVAEGGYAAALLLDGWAMLGRPDLRAGEEALRRWLSASALVRGQEEGGT
                     VVVVAEPTERVVQALVRWDPAGFARRELADRAELGFPPVSRMASVTGPPEALAAFLQNA
                     GLPPEAEILGPVPAPSAAPGRARRPGDAPPGETWERALVRVVPGRGAALARALKTALAA
                     RTAKGANDPVRIRIDPPDIG"
     gene            complement(18872..20080)
                     /gene="metK"
                     /locus_tag="C6W96_RS04685"
                     /old_locus_tag="C6W96_04675"
     CDS             complement(18872..20080)
                     /EC_number="2.5.1.6"
                     /GO_function="GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="metK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009187586.1"
                     /locus_tag="C6W96_RS04685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W96_04675"
                     /product="methionine adenosyltransferase"
                     /protein_id="WP_006123164.1"
                     /transl_table=11
                     /translation="MSRRLFTSESVTEGHPDKIADQISDTILDALLREDPSSRVAVETL
                     ITTGLVHVAGEVTTKAYADIPNLVRNKVLEIGYDSSKKGFDGASCGVSVSIGAQSPDIA
                     QGVDTAYEKRVEGDEDELDKQGAGDQGLMFGYACDETPELMPLPIHIAHRLSRRLSEVR
                     KNGTIPYLRPDGKTQVTIEYDGDKAVRLDTVVVSSQHASDIDLDSLLAPDIREFVVEHV
                     LAQLVEDGIKLDTEGYRLLVNPTGRFEIGGPMGDAGLTGRKIIIDTYGGMARHGGGAFS
                     GKDPSKVDRSAAYAMRWVAKNVVAAGLAARCEVQVAYAIGKAEPVGLFVETFGTAAIDT
                     EKIENAIAEVFDLRPAAIIRDLDLLRPIYAQTAAYGHFGRELPDFTWERTDRVDALRAA
                     AGL"
ORIGIN
        1 atgggcctgg acccgaacct cgcgatcatg atgtccggtg tcgcgaccgc catcttcctc
       61 ctggcgacca agggccgggt gcccagctat ctgggctgct cgctctcctt cgtcggtgtc
      121 gcggccacga tccgggcgag cggcggggac agcgcgaccg tcacgggcgc ggtgctggtg
      181 gtcggcgcgg ccctgttcct ggtgggtctg gcggtgcagc ggttcggcgc gcggatcatc
      241 cacgcggcga tgccgccggt ggtgacgggc gcggtcgtga tgctgatcgg cttcaacctg
      301 gcgccggtga ccgcctcgac gtactggccg caggaccagt ggacggcgct cgcggtcatg
      361 ctgttcaccg ggctcgccgt ggtgtgcctg cgcggcttcc tctcccggat cgcgatcttc
      421 ctggggctgg tcttcggtta cgcgctgtcc tgggtgctgg acctggtctt cgggaagatc
      481 cactccccgg cgggcggggc cgaggccgtc gaccactggc gcctcgatct ctccgccgtc
      541 gggcaggccg actggatcgg gctgccgtcc ttccacgcgc ccgccttcga gtggtcggcg
      601 atcctggtgg cgctgcccgt ggtgatcgcg ctcgtcgcgg agaacgccgg gcacgtcaag
      661 gccgtcggcg agatgaccgg cgattcgctg gacgacaagc tcggcaccgc catcgcggcg
      721 gacggcgcgg cctccatgct ctccaccgcc gtgggcgggc cgcccaacac cacgtactcc
      781 gagaacatcg gcgtgatggc cgcgacccgc gtctactcca cggccgccta ctgggccgcc
      841 gcctgcttcg cgctgctctt cggcctgtgc ccgaagttcg gcgcggtcgt cgccgcgatc
      901 ccgggcgggg tgctcggcgg gatcacggtg atcctgtacg ggatgatcgg cctgctcggt
      961 gcccagatct ggctcaacgg ccgggtggac ctgcgcaatc cgctcaacct ggtcccggcc
     1021 gccgcgggca tcatcatcgg cgtcggcggg gtcagcctga agatcaccga caacttcgaa
     1081 ctgggcggca tcgcgctcgg cacgctcgtg gtgatcaccg gctaccacgt gctgcgggcc
     1141 ttcgccccgg cgcacctcaa gacccaggaa ccgctgctgg attcggggac gtcggcgtac
     1201 gacgagaagc cggggcccga aggaccggcc ggacccgaga agagctgagc cgtccgggag
     1261 cggccgaggc tcaccccgtg gccagggcgt aggcgtactc cggggtgaag gagcccgccg
     1321 cgcccgagca gccgtcggac tcccccggca gcttcaccca caggtacgcg tcgatccggg
     1381 cctcgccggt ccgtgtcgtc ggggtctgcc cgagcgcccg gcccgccggg tcgcaccact
     1441 gaccggcggg cggcgcgccg ttgccgttgc ggctggtgtc gacgaccgcc ccgaggccgg
     1501 ccgggccgcc gagcgcggcg agcacccggc gggcgtaggc ccgctcgtcg gcggtgcggt
     1561 ggaagttggc cacgttggtg aagatgccgt cgccgttggt ggccgctccg gcggcccgga
     1621 gcgcggcggc ctgtttcgcg ggggcgtgcc agcccgagtg gccgccgtcg aagtagaccc
     1681 gggcccgcgg attggctgtg cgcagggtgc gtccggcccg ggccagcgag gcgaagcggg
     1741 cggcccggtc ggaggcgctc aggcagtcgg agagggcgat ggcgtccggc tccaggatca
     1801 cgatcgccgc tcccgcgccg agcccctcgg cgaactgccg tatccaggcg tcgtacgccg
     1861 cgaggtccgg ggcgccgccc ttcgacgcgc cgccgcagtc ccggtcgggt atcgcgtacg
     1921 ggacgagcac cgggatccgt cccgcggcgg ccgcgccccg ggtgacctcg cggacctgcc
     1981 cggctatctc gcccgggttg tgggcggcga accagacggc ggcgggccgc tccgcgatcc
     2041 gggactcgat gaccgggcgg cgcgggtcgt cggggtgggc ccgcacccag tccaggacct
     2101 gggagtccgg gtggcggaac agccgggcac gaggcgcggg tgcgggcgtc gccgacgggg
     2161 agggcgggag ctcggggacg gcgctcgggc gggctgtggt gcgtgagggg gacggggccg
     2221 gagcggggcg ggcggaggag gcggacgggg cgggggcggt gggcgtcggc gtggggacgg
     2281 cggggagggg ctggaggacc ggcggagccg tcggttcggg gcgggccgtg tcgcgcccgt
     2341 cctgatggcc cacgtcgatc agcccggccg tcgcgccgat cgccaccacc gccgaggcga
     2401 cggcgagcag ggcgtgacgg cgggccgcgc ggcggcgttc acggtgagcg gtgcggcgtc
     2461 gtacgcgggt gcccggcact cctcgatccc cttttccggc accgctgttc gtccgttccg
     2521 atgaatactc gggccggtcg gcgccgtggc gagcctaagg ctgggacgct ccgcgcatga
     2581 cgcagatcga gcagtccgca gtaccggccc agggcggcgg cccgccgacg ggcggcttcc
     2641 cggtgatcga acgtatgcgg gaattgcggt cccggtggcc gtacgaggac ggggtggcgg
     2701 tcttcaaccg ggtctatctg gaggccctgg agacggccgg accggagctg ggcaggggcg
     2761 ggcacgacgg ccgggaagcc gccgccctgc tgggcgtacg gtgcgccgag cgctatctgt
     2821 cggccgccga gacggccacg gcgggcgggc ggccgccgga gtgctggcgg ccgttgctcc
     2881 cctgccgccg ccatcccggc gtacgtccgc tgcagttcgc cctcagcggt ctccaggcgc
     2941 acgtgggcca cgatctggtc ctggcggtgg tggacacctg tcgtactctc ggctgcgatc
     3001 cgccggacct ggaaggggag ttcgagcgcg tgggcgatct cctcgcgttg ctggaggagc
     3061 ggatccacga cgagctgatg ccggggcccg acctgctggg gatcgcggat ccgctgaccc
     3121 atctggtgag ttcctggagc ctggagcggg cccgcgaggc ggcctggtcg gcggcccgga
     3181 cgctctggcg gctgcgcgaa ttccctccgc tggccgagga gttccggaag cggaccgacg
     3241 cgggcgcggg tctggtgggg cggcttctgc tcaccccgtg ccgctgacgc ccgcgtcggt
     3301 aaggcctcgg gctcagtcct ccggaagctc gaccggggcg atctcgtcga agacgtcgcc
     3361 ggggccgggg ttggtcgcgt cggtcgcccc gccgaactgg tgcatgacgc cccacacggc
     3421 gttcagcgcg gtctgcacgg cgccctcggc ccagccggcc gtccaggaga tgtcgtcccc
     3481 ggcgaggaag atgccccgct tgtcctccgg cagccggtcc tgcatgaagt gggtgaacag
     3541 ccgccgctgg tagcggtagt ggccgggcag gttggccttg aacgcgccca tgaaccaggg
     3601 ctcgttctcc caggagacgg tgaccgggtt gccgatgatg tggctgcgga tgtcgacgtt
     3661 cgggtagatc tcgccgagcg acttgagcat gacctccatg cgctccttcg gggagagcgg
     3721 cagccacttc aggctgtcgt cgcaccacgt gtaggagagg cagatgacgg cgggcttgtc
     3781 cggcccgtcg tccaggaggt acgtcccccg ggtcatccgg tcggtgagcg tcatcgacat
     3841 ggtgtcgcgg ccggtggtct cgtccttgtc cagccagaac gggcggtcga ccgggacgaa
     3901 cagcttggac gactccatgt agtgggtgcg ctccatcgcc gtccagtggt cgatcgggaa
     3961 gagcgcgtca tcgcagtcga tcttggagag cagcagccag gactggccgg tgaagaccgc
     4021 ggcccggaag gtgcggatgt cgccggtggc gtcggtgacc gtgatgcggt tgccggccgt
     4081 gcgggtcagc cgggtgaccg cgccgcgcgg ctcgccgtcg tgcagggagg acagcgaggt
     4141 gccgagcggc cagtggacga tcttctgcgg ctcgcggtcc cacaggcgca gtgggagctg
     4201 ctggctgccg ccgacgatgc cgcggtggtg gtcgtcggcc tcggtgtaga cgacgcgcag
     4261 gatctccagg atggagttgg ggaagtcggt gtcccagccg ccggtgccga agccgacctg
     4321 gccgaagatc tcgcggtgcc ggaacgactt gaaggcctcg gactcgcaga ggaagccgta
     4381 gaaggtctgg ttgtcgagcc gctcgacgag ctgcgaccag atctcccgga tgcgcgggac
     4441 gtcgcgctcg cgcagcgccc ggttcatgtc ggagaagtcg gcgccctcct ccagacaggc
     4501 gttccaggcc tcggccacgt cgcggtagac ctgcggcagg tcgtcgatgg tctcggcgta
     4561 gtgcgactcg cccttgaggt ccacgacggt cgagggcgtg gccggggaga gcgggttggg
     4621 gaagggccgg gtctgcaggc ccaccaggtc gatgtagtgc tggagcgcag tggaggacgg
     4681 cgggaagcgc atggcgccca tctcggcggt gaggtcgccg tcgcagccgt cgaaaccgac
     4741 ggtgcgcagc cggccgccga tccggtcggc ctcgtacacg acgggcttga ggcccatctt
     4801 catcagctcg tacgcggcga tgatgcccga gagcccgccg ccgatgacgg cgacctcctg
     4861 gccgtgctcg gtcgcgggta tctgcccgag acccgccggg tgggcgagga agtcgtcgta
     4921 cgcgtacggg aagtccggcc cgaacatggt gatcggcggg gcggccgcgt cggtgtgctg
     4981 gacggcgttg ggcaccgtgg acgtcatggg gtacggactc cttgcgcggt acgggaagtt
     5041 cggggaggga gcgggctcag gcgagggagc cgtagaggcc ggggcggcgg tctgcgagat
     5101 acgggttggc ggcgcgcgac gccgccagga actccgggtc cacctcgccg aacacgagtt
     5161 cctcgccgcg tccggcgcgg gtgcgcacca ccccgtcggg gccggccagg cagctgagcc
     5221 cgacgaactc gaactcccct tccgggccgg tgcggttgac gtacgccacg tacatctggc
     5281 tctcgaaggc ccgtacgggg acgacggatt cggcgacgaa ctggaagggg tgcatctgcg
     5341 cggtgggcac cagcagcaga tcggtgccgg ccaaggcgtg cgcccggacg ttctcgggga
     5401 actcgacgtc gtagcagatc agcaggccga tgcggatgcc gtcgaggtcg gcctggacga
     5461 cggtctgctc gccgggggtg aaccactcct gctcgaagca gccgaacagg tgggtcttgc
     5521 ggtagttcgc gagccggacg ccgtcggcgc cgatgagccg ggaggcgttg aagatccgct
     5581 cgccgtcgcg ctccgggtag ccgtagagga cggcgaggcc gtggcgtacg gcgatctcgg
     5641 cgacggcctg ggcaccgggt ccgtcggcgg gctcggccag gacgggcacg gcgtcgccga
     5701 tggcgtatcc ggtgaggaac agctcgggcg cgaccagcag ccgggctccg gcaccggcgg
     5761 cccgggcggc ggcctcgtcc agcgccttca ggttctcggc gacggcgccg ggccgtccgg
     5821 agctctggag cagggcggtg cgcaacgacg gcatggctga cctcgggcgg tgcgggcggg
     5881 gtggggagac gtatcgaagg tacgtggccc ggatcggccc ggacaaggcg cgagcgttgc
     5941 gcgtcgaccg ttgattcgtt gcgcgggaag ggcctggggc agcgaatcgt tgcgtcggac
     6001 atcaccgcag gtcagcgggg tgatgtgcgc cacccgtttc agaccggcgg ggcctccgcg
     6061 gagtagcgcc gcagcagcgg tgagagcacc agcaccgact tcgtacgctc gacgtacggc
     6121 tcccccgcga tgcgctccag gacctgttcg aagtggcgca tgtcggcggc gaagacctgc
     6181 accaccgcgt ccgcctcgcc ggtcaccgtg gaggccgagg cgatctccgg gtagcgggcg
     6241 aggccctgct tgatcgcgtc cggggaggtg ttgcggctgc agtagatctc gatgaacccc
     6301 tcggtctccc agccgagcgc cgccgggtcg acccgcacgg tgaaaccggt gatcgcgccc
     6361 tcggcgcgca gccggtcgac gcggcgtttc acggcggggg cggagaggcc gacgatggcg
     6421 ccgatgtcgg cgtaggagcg ccgggcgtct tcggcgaggg cgtggacgat gcgttcgtcg
     6481 aggtcgttca ggcgcacgtc gggcggttca ctatctctgc ggtgggtcgg cttgcgggag
     6541 gcggcgcgtg ccgcctcccg cagtagacca cgggccgccg ccccgggcat gccaggtgcg
     6601 gcggggcagc ccgtcagaag gggaacagcg agcggccgtg ctggatggag atccacttct
     6661 gggtggtgaa ggcctcgatc atggagtcgc cgttcagccg gccgaggccg gagctcttct
     6721 cgccgccgaa ggggacgatc ggctcgtcat ggacggtgcc gtcgttgatg tggatcatgc
     6781 cggtgtggat gcgctgcccg acccggacgc cgcgctcgat gttgccggtg tggacggcgc
     6841 cgctgaggcc gtacggggtg tcgttggcga tccggacggc ctcgtcctcg ccgtcgaagg
     6901 ggatcagcag ggcgacgggg ccgaagatct cctggtgcag gacgggcgag tcggcggcga
     6961 ggccggtcag cacggagggg ctgacgaggt tgccgtcggc gcggccgtgc aggagggccg
     7021 tcgccccggc cgccacggtc tggtcgacga gcttggagac ggactcggcc tgcgaggagt
     7081 tgatcagcgg gccgatctgg gtggccgggt cggcggggtc gccgacggtg agggacgcga
     7141 ccttggcgac gaacttctcg gtgaactccg cctcgaccgc gcggtcgacc aggatgcggt
     7201 tggcggccat gcagacctgg ccctggtgga tgtaccggct gaagaccgcc gcgtcaacag
     7261 cgtagtccac atccgcgtcg tcgagcacga tcagggcgct gttgccgccg agttcgagga
     7321 cggcgcgctt gaggttctgg gcacagacgg tggcgacgtg ccggccgacc ttgtccgagc
     7381 cggtgaagga gatgacctgc ggcacggggt gctccagcag ggtgtcgccg atctccgcga
     7441 tgtcggtgat cacgacgttc agcagcccgg cgggcagccc ggcgtcctcg aagaccttgg
     7501 cgagcagggt gccgccgcag atcggggtgt tctggtgcgg cttgaggacg acggcgttgc
     7561 cgagggccag cgcgggggcg acggacttca gggagagcag gaaggggaag ttgaacgggc
     7621 tgatcacgcc gacgacgccg acgggcacgc ggtagacgcg gttctccttg ccctcgctcg
     7681 gcgaggggag gatctgtccg gcggggcgca gggccagctg gatcgcctcg cggaggaact
     7741 ccttggccag gtgcagttcg aatccggcct tcagccgggt gccgcccagc tcggcgacga
     7801 tcgcctcggc gatctccggc tcgcgctcct cgacgatgcg cagcgccttc tccaggacgg
     7861 cccgcctgct gtacgggttg gtgtccgccc acgcctgctg cgcgcgctcg gcggcccggt
     7921 aggcctggtc cacctcgtcg gcggtggcga ccgggatcga ggcgagcttc tccccgtcga
     7981 acgggttgaa gtcgatgatg tcccaggacc ccttccccgg cctccactcg ccgtcgatgt
     8041 actggtgggc caggtcagtg aagaaggaca tgagatccct taccgcagag aggcaggcag
     8101 ctgagtgcgg ttcatattac ttagatttca acagagttga agcgcgaccc cggccacgcg
     8161 gacaggccgg aaacggcccc gccccctccg gcgtggaaca gccggagggg gcggggccgt
     8221 tggggcgacc ggaagatcaa ctccagctgg cgtgcagcgg cttgccctcg gcgtaaccgg
     8281 cggcgctctg gacgccgacg accgccttct cggcgaactc cgccagcgag ccggcaccgg
     8341 cgtaggtgca ggaggagcgg acgcccgcga tgatcgagtc gatgaggtcc tcgacgcccg
     8401 ggcgggccgg gtcgaggaac atccgcgagg tggagatgcc ctcctcgaag agcgccttgc
     8461 gggcgcggtc gtaggcggac tcgtccgagg tgcggttctt cactgcgcgg gccgaggcca
     8521 tcccgaagga ctccttgtag aagcggccgt cggcggactg ctggaggtcg ccgggcgact
     8581 cgtaggtgcc cgcgaaccag gagccgatca tcacgttgga cgcgcccgcg gcgagcgcca
     8641 tggcgacgtc gcgcgggtgc cggacgccgc cgtccgccca gacgtgcttg ccgtgcttcc
     8701 tcgcctcggc ggcgcactcc aggacggcgg agaactgcgg gcggccgacg ccggtcatca
     8761 tccgggtggt gcacatggcg ccggggccga cgccgacctt gatgatgtcc gcgcccgcct
     8821 cgatcaggtc gcgcacaccc tcggcggcga cgatgttgcc cgcgacgatc gggacctgcg
     8881 ggtcgagggc ccgcacggcc ttcaccgcgc tgatcatgga ttcctggtgg ccgtgggcgg
     8941 tgtccacgac gaggacgtcg gcgcccgcgt ccaggagctg cttggccttg ccggccacgt
     9001 cgccgttgat gccgacggcc gccgcgatgc gcagcttgcc ctcggcgtcg gtggcggggg
     9061 tgtagagcgt agcgcgcagg gcggccttgc gggtgaggat gccgacgagg cggccgtccg
     9121 cgtcgaccgc gggggcgagc ttgcggttgg cgccgtcgag cttgttgaaa gcgtcgcgcg
     9181 ggtcgatgtc cgcgtccagc agcacgaggt ccttggacat gacctcggag agctgggtga
     9241 agcggtcgac gccgctgagg tcgtgctcgg tgacgactcc gacgggacgg cggtcggcgt
     9301 cgacgacgac gcccgcgccg tgcgcccgct tgggcagcag cgagagcgcg tcggcgacgg
     9361 tctggccggg ggccagctcg atcggggtgt cgaggacgag gtggcgcgtc ttgacccagg
     9421 agatgacgtc ggtgacgacc tcgatcggga tgtcctgggg gatgacgacg aggccgccgc
     9481 ggcgggcgac ggtttcggcc atccgccggc ccgcgatggc ggtcatgttg gcgaccacga
     9541 gcggaatggt ggtgccggtt ccgtcgggcg acgagaggtc cacaccctgg cgggagccga
     9601 ccgcggagcg gcccgggacc atgaagacgt cgtcgtacgt gaggtcgtac gggaccgcgg
     9661 gggactctgt gtagcgaccg gtgcccggct caagaaaacg cataagactc attttttcat
     9721 acgaaaccgc gcaggtcgtt tcccggaaga cacagcaaaa gacccccgtt ttcgtctgat
     9781 cctccgaaga ggcggccggg ggtcccgggc aagtgaacct gccttgccca cggactctac
     9841 ccgaacagga ttcgaagcat tcgtgatcac catccctgga ccgggtgaca aggggtcagg
     9901 tagcttcaaa gccgcaggtc tcgggggtgt cggaagcgtc gatccggctc gtcggcaacc
     9961 ctgggcacac cgtttgaccg gagaggatcc cgatccgcct gtggacagcg aactgccgga
    10021 catctactgc ccgttcccgc agcggaccaa tccgcacgtg gcgcacaccc gggggcatct
    10081 ggacgcctgg accagagcga cgggtctggt ccatcgcgag tccgcgagga accgattcga
    10141 acaagccgat ttcggggcgt tcgtcggcat ggtctatccg acggccgacg aggagaacct
    10201 cgatctggtg gccgactggt tcgtctggct cttcctggtc gacgaccagc tcgacgacgg
    10261 ccacctcggc cgttcacccg accgggtgag aagcgtggtc gaacggatgc gcgcggtcgt
    10321 cgacggctcc gcccccgagc cgctgcccgg cgaggaggtc ccggccgccg tgacggccct
    10381 ggccgacctg tggaaacgta cgacgccgaa cgcggccccg cactggcgga cccggttcgc
    10441 ctggcatctg gtgacctacc tcacgaccgc cacgacctgg gaggcgggca accgcgccga
    10501 ggacgtggtg ccctcggagg acacgtacat cgccaagcgg cggcacaccg gggccatcca
    10561 cgtctgcatg gacctcatag agatcgtcgc gggcatcgag gcgccggagt cgctccacaa
    10621 cgacccccgc ttcatcaccg ccctggaagc cgcgtgcaac cacgtctgct gggccaacga
    10681 cgtgtactcc ttcgagaagg agcaggtgct cggcgagatc cacaacctcg tccacctggt
    10741 ccgccaccac cggggcctcg gggagcagca ggcgctggac cacgtcgccg agcggctcgc
    10801 gatggagacc gagcggttcc tgaccgccga ggacgagctg ctggagctgt atccggagct
    10861 gtcggggctg ctggtgccct acctggacgg gatgcggagc tggatgcgcg gcaatctgga
    10921 ctggtcgcgc cagacgcccc gctacaaccc ggcggacgtg gggcagtacg aggagcccga
    10981 ggagtatctg gaggagacgg tgctgggcat cccgcccgcg cgcaccgagg ccgccgcccc
    11041 cgccccgtgc gcggccaagg cgcccccggc cggctgaggg agggacgaca tgccgagggc
    11101 cgtgcacctt gcgggtgcac ggccctcggc gcgtcctcgg tgtcactccc cgtcggggtc
    11161 ggcccgctcc agcgccgggc ggacgcccgc ggcggactcg gtgagcagat agtcggccgc
    11221 agcggtgtcc gtgaccaaac tggtgaccag gccggagcgg agcaccgcgc cgatcgccgc
    11281 cgccttgcgc tggccgcccg cgatcgcgac cacctcgggg atccggcgca gccggtccgc
    11341 ctccacggtg atgcagcgct cccccaggtc gcggccgacc ctgcggcctt ccgcgtcgaa
    11401 gaggtgcgcg gacatctcgg cggcgacgcc gagcgaggcg tagtgggcgc gctcctcgtc
    11461 cgagagcatg tcgtggaccg tggagatgcc cggctcccag gagccgatgg agacggcggc
    11521 gacggtcacc ttgtcgaagt actcgaaggc ccgggcgatg ccggtctgct cgcgcagcgc
    11581 ggcggccgtc gcggggtcgg gcagcagcat cggtgcgtag atggggtgcg cctcgccgcc
    11641 ggagacctgg gccgcccggc ggaccgcctc gaccgagccg cgctcggcgg tgcccgcgtc
    11701 gtacaccccg gtcagctgga cgaccgtgca gggcggcagc cggtcgaggg cggccgccat
    11761 gtggatggtg gagcggcccc aggccaggcc gagcacatcg ccctcggcca ccagctcgcc
    11821 gaggaggtcg gccgcgacct cgcccagatt ctccgggtcg ggggcgtcgt cctgttcctc
    11881 ggccggggat tcgacgacca ccgcgtgccg cagcccgtag cgggcgcgca gggcgtcgga
    11941 gcgttcggcg tccagctcgg ccgggacccg gatctcgatg cgtacgagat cgcgttcgag
    12001 ggcggtctcc aggacccggg ccaccttgaa gcggctcacg ccgaactcct cggcgatctg
    12061 gatcttggac ttgccctcca ggtagaaccg gcgggccatg gccgccgcct gcaccagctc
    12121 cgcgggtccc atccgcatgg ctgaccgacc cgccgagatg ccagacaccg cgatctcctc
    12181 actgctgttc acacgcccga tacgccgttc atcctgtcag atccggcgat ccttgatcgg
    12241 ccctgtcgga ccgcgttcat ctgcccttgg ttcagtggtc gcatgcccag ggggccgcgg
    12301 ccgtcgccac gtccgccaga gcccgcaggt cccgcacggc cgccgccggg tccgccgccc
    12361 cgtagaccgc ggatccggcc acgaagacat cggctccggc ctcggcgcag cgctcgatgg
    12421 tggcggccga gaccccgccg tccacctgga gccacagttc gagcccgtgc ttgctgatca
    12481 gctcccgggt acgccggatc ttcggcagca tgatgtccag gaaggcctgc ccgccgaagc
    12541 ccggctcgac cgtcatgatc agcagcatgt ccagctcggg cagcaggtcc tcgtacggct
    12601 cgatgggcgt cgcgggcttg agcgccatcg aggcgcgcgc ccccttcgcc cggatctccc
    12661 gcgccaggcg caccggcgcc gcggcggcct cggcgtggaa ggtgacggac ccggcgccgg
    12721 cctccacgta ctgcggggcc cagcggtccg cgtcctcgat catgaggtgg cagtccagcg
    12781 gggtgtccgt cgccttgctg agcgcctcga cgatcggcac gccgagggtc agattgggca
    12841 cgaagtggtt gtccatgaca tcgacgtgga gccagtccgc gccttcgacg gccttcgcct
    12901 cctcggcgag acgcgcgaaa tcggcggaca ggatgctggg gttgatctgc gccatgcccc
    12961 aagcctgcca cgtctgcggc cggttccccg cctcgatccc ctccgaagcc tcacacggcc
    13021 ctcacagtcc gcacattctg ggcattttgc cagggcttta cttttctttt gccgtacggg
    13081 cgggcgcgct gacgccgcga tattcagccg gtccggcgca gcagagccag atacatcgcg
    13141 tccgtgccgt ggagatgcgg ccagagctgg acgtcgggcc cctcgcccag ggcgggcacc
    13201 ccgggcagca gcgggcgggc gtcgatccac tccgcctcga cgggctcccc accgcggccc
    13261 ttgagcacgt cctcgacgac cacccgggtc tccgcgagat gcggcgagca ggtggcgtaa
    13321 ccgaccacgc cgccgacccg tacggccttc aacgcctcgc gcagcagtcc gcgctggagc
    13381 ggggcgaagg cctccaggtc ctcggcgcga cgccgccagc gggactccgg gcggcggcgc
    13441 agcgcgccga gtccggagca gggcacgtcc atcaggatgc ggtcgaaggt gccgggcagc
    13501 cacggcgggc gggtgccgtc ggcggtgatc acctggtacg ggccgggatt gccggcgagc
    13561 gcccgctcga ccagccgggc gcggtgcggc tgcttctcgg cggcgagcag cgtcgcgccg
    13621 cgttcggcgg ccagcgccgc gaggagggcg gccttgccgc cggggcccgc gcagccgtcc
    13681 agccagcgcg agtcgcggcc ctcgacgggg acggcggcca gggcggcggc gacgagctgg
    13741 ctgccctcgt cctggacgcc cgcccggctc tcccggacgg cctccagcgc gccgggctcg
    13801 ccgccctcgg ccatccgcac ggcgtacggg gaccagcggc cgggcaggga gttgtcctcg
    13861 cccagggcct tgaccagctc ctcggtggtg gaacggccgg ggcgggcgac cagggtcacc
    13921 tcgggccgct cgttgtcggc ctccagcagg tcctcgatgc cggcccggcc cccgcccagc
    13981 gcgtcccaga gggcggagac gatccagcgg gggtgggagt ggacgacggc gaggtggtcc
    14041 tcggcgtcct cgtcgtacgg cggggcgacc ttctccaccc agccgtcgag gtcgtgcgcg
    14101 gtgaccttgc gcagcaccgc gttgacgaac ttcgcacgcc cctcccccag caccacccgg
    14161 gccagctcca cactggcgga gacggccgcg tgggtgggga tacgggtgcc gagcagctgg
    14221 tggacgccca tgttcaggac gtccaggacc ggcgggtcga cctcgcgcag cggccggtcg
    14281 atgcaggccg ccacgatcgc gtcgtacgtg ccctggcggc gtagcgtccc gtagaccagc
    14341 tcggtcgcca gcgccgcgtc ccggccgtcg aagtcgccct tggcgcgggc cttcttcagc
    14401 agcgggggca gcacgaggtt ggcgtacgcg tcccgttcgt cgacggcccg cagcgcctcg
    14461 aaggcgagga agcggaccgg gtccttcttg ggccggcggt gaggcttggc gggacggcga
    14521 cgcggctggt cgttcacgtg aaaggtgctc cgctgaaggt gctgaaggtg agggggcgaa
    14581 ccctcccagc gtacgacgcc gtcccgggct tcccgaacga gaggttcccc ggccacgggg
    14641 gctacgagcc cagcagctcg ccgtgggcga tccggacgcc gcgcgcccag tcggcggccc
    14701 gcatcggctt cttgccctgc ggctggaccc agagcagctc gacggcgtgc gatccggtgc
    14761 cgacgtacac gttgttcttg gcggccgaca gctcgccggg ggccaggtcc gtacggtcca
    14821 ggacgggggt cgcctggatc agcttgagcc tctcgccgcg gaacagggtc caggcgccgg
    14881 gggcaggggt gcagccgcgg atcacccggt cgacgcgcag ggcgggcgcg gaccactgga
    14941 cctgggcgtc ctcgacggtg atcttcgggg ccagggtgac gccctcgtgc ggctggggca
    15001 cagcgtgcag ggtgtcgtcc tcgatgccgt ccatggtggc ggcgagcagc ccggcgccgg
    15061 cgaaggcgag ccgggtgagc aggtcgccgc tggtgtcggt cgggcggatc tcctccgtga
    15121 ggacgccgta gaccgggccg gagtcgagcc cttcctcgat caggaaggtc gacgcgccgg
    15181 tcacctcgtc cccggccatc agggagtgct gcacgggggc cgcgccccgc caggcgggca
    15241 gcagcgagaa gtgcaggttg acccagcccc gggccggcac gtcgagggcg accttgggca
    15301 gcagggcgcc gtaggcgacg accgggcagc agtccggggc gatctcgcgc agccgggcga
    15361 ggaactcctc gtcccggggc ctgacgggct tgagcacctc gatcccggcc tcctccgccc
    15421 gctcggccac cgggctcgcg acgagtcggc ggccccgccc ggcgggggcg tcgggacggg
    15481 tcacgacggc ggccacctca tggcggtcgg aggcgatcag ggcgtccagg gcggggacgg
    15541 cgacttcggg ggtgccggcg aagacgagct tcatgggtgg ctgactgcct ctcgggccaa
    15601 gacgtacggt gacgagcagc acaccagtct agggtctcgg gtcggaccgg gcccggccgc
    15661 tcccgtgcgc aggggcggcg accccctcgg tacggggcgg cgactccctt gcgcggggcg
    15721 gcgaccaggg ggcgtacgcg cgccgcgcac gccccgtgca tatgcacata cgccccgata
    15781 gcgtgaccac atacccggct cgggcgttgg tcaaaggaga ttgaccgaag cgggccgccc
    15841 cgattgcggc ccgatccctt tcaacgccgg ttcgagaggc ttcttcatgg ccgaccacgc
    15901 aacgcacgac gcccaagcgc gggccagtct gcatcttctg gtgcgggaca tcgagcgggt
    15961 caggcggcag gtggacgcgc tgcgcaccct caccgcccag ctgggcaacg tctaccgtcc
    16021 gcgccgctcc ggcccttccg cgggcttcgt cgtctacggc agggccccgg cccccaccgt
    16081 ccgcctcgcg caggaactgc gggacagcgt cgagaccctg gtgacggccg cggtggactt
    16141 cgaccgctcg ctgggcttct cctgggacgc ggtgggctcc gccctcggcg tcaccaagca
    16201 ggccgtccac cgccgctacg gaacccgccg cgccaccccg cagcccgccg ccgagacggg
    16261 cggcgagaac acggccgtgc cgcgcccggt ctccgtcggc accggcctca ccggatcctc
    16321 cgccaagggg tccggctccc cggtgcccac ggtcccggcg gcccgctcga tgccgccgca
    16381 gccgtcggcg gccccgcagc cggcccgcga ggagctgcgc cccggtgcgt tcccgggccc
    16441 gcgcaacggc tgaccgtaca ccgcccttct gccccaccgt gccggtcgca cggcggggca
    16501 gtcccctgtc cgggcccggg gccctgtcgc gctctctgtc cgggcccggg tcacaaagga
    16561 agctgcgtcg cggggctcag ccgatgtccg gcgggtcgat cctgatgcgt accgggtcgt
    16621 tcgcgccctt ggccgtgcgg gccgcgagcg ccgtcttcaa ggcgcgggcg agcgccgccc
    16681 cgcgccccgg taccacccgg accagggccc gctcccaggt ctcgcccggc ggcgcgtccc
    16741 ccggtctgcg ggcccttccg ggcgcggccg agggggccgg caccggtccc aggatctcgg
    16801 cctccggcgg cagcccggcg ttctggagga acgcggccag ggcctcgggc gggccggtca
    16861 ccgaggccat ccgggagacc ggcgggaagc ccagctcggc gcggtccgcc agctcccgcc
    16921 gggcgaaccc cgccggatcc cagcggacca gcgcctgcac cacacgctcc gtcggctcgg
    16981 ccacgaccac caccgtgccg ccctcctcct gcccccgcac cagcgccgac gccgacagcc
    17041 accggcgcag cgcctcctcc cccgcgcgca gatcgggccg gccgagcatg gcccagccgt
    17101 ccaggagcag ggccgccgcg tacccgccct cggcgacggg ctccgcgccg ggcgtggaga
    17161 ccaccagggc cggggcgtcc ggcaccgcgt cgaggatgtg gtcgcgcccc gaggtgcgga
    17221 cgggcacggc gggaaaggcc cggcccagct cctccgcggt gcggcgggcg ccgacgatcc
    17281 gggcacgcag ccgggtggag ccgcactccg cgcagctcca ggcccgctcg gcccgcccgc
    17341 accaggcgca gttcagatcc tgttggtccg gcgcttccag ggggcccgcg cagtgccggc
    17401 agcgggcggg ggtgcggcag cgttcgcagg cgaggcgggg ggcgtaaccg cgcctcggga
    17461 cctggatcag caccggtccg gtgcgcagac cgtcgcgcac ggccccccag gcgaggctgg
    17521 gcaagcgggc tgaacgggcg gccccgtccc gggccagctc gccgtccccg accgtacgga
    17581 tcaggggcgc ggcccggcgc agccgttcgc ggtccgcgag gagcggcagt gcccagccgc
    17641 tctccacgag ctgggccgcc tcgaccgtgc agctggtccc gccgagcagg aagccgcagc
    17701 ggccctgggc cgaccgcagc tccaggacct cgcggacatg cgggaagggg gcgttgtcgt
    17761 cgctgtggct ggagtcgccg tcgtcccaga cgacgacgag cccgaggtcg cggacgggcg
    17821 cgaacatggc ggcccgggtg cccacgaccg cccgcaccga gccccggcgt accgcgagcc
    17881 actggcggta gcgcttctcg gggccggatt cggcggtcag cagggcgtgc cgacccgcgc
    17941 cgagcgcctc ggtcagggcc gcgtcgaccc gtgcggcggc ccgcccgtcc gggacgacga
    18001 cgagggcgcc gcgcccggag gagagcgtcg ccgcgacggc tccggcgatc tccgcgggcc
    18061 agtgcggtcc gggcagggcg gtccacacgg cgcgcggggc gccgccctcg gccagggctc
    18121 gcaggaaggc ggggccctgg ccgtaccgct cccaggtgcc cggatccggg ggcgggggcg
    18181 ggggcagcgg gtccggggag ggcttggcct cggcgcggcc gttgcggggc gggacggcga
    18241 gctggaggac gtcggcgagg ctgcccgcgt accggtcggc gacggcgcgg cagagggcga
    18301 gcagctcggg gccgaggacc ggctccgggg agaccacgga ggcgagggcg gccagcgcgc
    18361 cctggtagtc ggagtcggcg cggcgctcga cgatgaagcc gtcgatcagg ccgccgccct
    18421 cgcgccgccc gccctggacg ttgcgcccgc cggccccgaa ccgaacccgc acccggacac
    18481 ccggctgtgc gtcggtgtcc agctcctggg gcaccgcgta gtcgaaatac tggtcgaggt
    18541 ggaggacgcc cttgttgacc aggacgcggg cgacgggcag ctcgtcggcg aggggcgcgc
    18601 cgcgccaggt ccgcggcttg gcgcgcggca ccttggcccg gcgcacggtc tcccggatca
    18661 gcgcaagctg ctccggcggc ccggcacccg gttcggcgga ctgctcgttc tcgctgctca
    18721 cagctgcatt cctaccagag ggcactgaca gtccagaggg cactgacagt ccggagagcg
    18781 cggaagtcgt gggggcacgg cagcggggcc cggccaccgt gttcggtgtc cgggccccgc
    18841 cgtcactcag tgccgatgct cgtaagggcc cttacagacc cgcggccgcg cgcagcgcgt
    18901 ccacgcggtc cgtgcgctcc caggtgaagt ccggcagctc ccggccgaag tggccgtacg
    18961 cggcggtctg ggcgtagatc gggcggagca ggtcgaggtc ccggatgatc gcggccgggc
    19021 ggaggtcgaa gacctcggcg atcgcgttct cgatcttctc cgtgtcgatg gcggcggtgc
    19081 cgaaggtctc gacgaagaga ccgacgggct cggccttgcc gatcgcgtac gcgacctgga
    19141 cctcgcagcg ggcggcgaga ccggcggcca cgacgttctt cgcgacccag cgcatcgcgt
    19201 acgccgcgga gcggtcgacc ttggacgggt ccttgcccga gaaggcgccg ccaccgtggc
    19261 gggccatgcc gccgtaggtg tcgatgatga tcttgcggcc ggtgaggccc gcgtcgccca
    19321 tcgggccgcc gatctcgaag cggccggtcg ggttcaccag gaggcggtag ccctcggtgt
    19381 ccaacttgat gccgtcctcg acgagctgcg cgagcacgtg ctcgacgacg aactcgcgga
    19441 tgtcgggggc gagcagcgag tccaggtcga tgtccgaggc gtgctgcgag gagacgacga
    19501 ccgtgtcgag acggaccgcc ttgtcaccgt cgtactcgat ggtgacctgg gtcttgccgt
    19561 cggggcgcag gtaggggatg gtcccgttct tgcgcacctc ggacagccgc cgggagaggc
    19621 ggtgggcgat gtggatcggg agcggcatga gttccggggt ctcgtcgcag gcgtacccga
    19681 acatcaggcc ctggtcgccc gcgccctgct tgtcgagctc gtcctcgtca ccctcgaccc
    19741 gcttctcgta cgcggtgtcg acgccctggg cgatgtccgg cgactgggcg ccgatcgaca
    19801 ccgagacgcc acaggaagcg ccgtcgaagc cctttttgga ggagtcgtaa ccgatctcca
    19861 gaaccttgtt gcgcacgagg ttggggatgt cggcgtaggc cttggtggtg acctcgcccg
    19921 cgacatgcac cagaccggtg gtgatcaagg tctcgacggc gacacgcgag gaggggtcct
    19981 cacgcaggag cgcgtcgaga atcgtgtcgc tgatctggtc agcgatcttg tcggggtgac
    20041 cctcggtgac ggattccgag gtgaaaaggc ggcgggacac atcgctccct ggggttgcag
    20101 cggctgctgg ctgatcatgg gtggcacgtc cgagagctgc gctcggtgcg taccgtcggc
    20161 cagtttatcg gtcacttccg gcgaccgggc caggtgtctc gccctttggg aggttcgtga
    20221 cgtgcgccac acagatcacc agtaggacaa ttcaccctcc tcggccgccg ttttcagcgt
    20281 tatggggcga tttcactcac ccgaagggct gatcaggaat tcggctggaa cctggcggaa
    20341 accagatccc agaccgtgtc ggcaagggct tccttggggc cgtacggcac cggcgtctcc
    20401 tggccgtcgg cggcgaggac gaccgcttcg ttctcctccg agccgaaggt cttgcgctcc
    20461 cccacctcgt tgaccacgag gaggtcgcag cccttgcggc ggagcttggc acgcccgttg
    20521 gccagcacgt cgtcggtctc ggcggcgaat ccgacgacga tctggccggc ccgggcccgc
    20581 tccccggcga cctcggcgag gatgtcgggg ttgcggacca gggtgagcgc gggcgcctcc
    20641 tcgccgtcct tcttcttgat cttgccggtg gcgtactcgg acgggcggaa gtcggccacc
    20701 gcggccgcca tcaccacaac gtccgcgtcg gcggcggcct tcaccacggc ctcgcggagc
    20761 tggacggccg tgccgacccg caggacatcg gccccggccg ggtcgggcag cccggtgttg
    20821 gcctcgatca gggtgacccg ggctccccgg gccacggcgg tgcgcgccag tgcgtacccc
    20881 tgcttgccgg aggagcggtt gcccaggaag cgcaccgggt cgagcggctc gcgggtgcct
    20941 ccggcgctga tcaccacatg gcggcccgcg aggtcgggct cgggaacccc gcgcgccagc
    21001 acccggcggc agacctcgaa gatctcaccg gggtcgggca gccggccctt gccggtgtcg
    21061 acgccggtga gccgccc
//
