LOCUS       NZ_PVWC01000013        14514 bp    DNA     linear   CON 05-SEP-2024
DEFINITION  Bacillus halotolerans strain DGL6 NODE_14_length_14514_cov_36.3066,
            whole genome shotgun sequence.
ACCESSION   NZ_PVWC01000013
VERSION     NZ_PVWC01000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus halotolerans
  ORGANISM  Bacillus halotolerans
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 14514)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Genotypic and phenotypic analysis of antagonistic Bacillus spp.
            isolated from rhizosphere soil of plants in Tibet
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 14514)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAR-2018) UG, NordReet, Marienstr. 27a, Greifswald
            17489, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. A5-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 38.3x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003003575.1-RS_2024_09_05
            Annotation Date                   :: 09/05/2024 04:49:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,923
            CDSs (total)                      :: 3,840
            Genes (coding)                    :: 3,703
            CDSs (with protein)               :: 3,703
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 9, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 8, 1 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 90 of 137
            Pseudo Genes (incomplete)         :: 71 of 137
            Pseudo Genes (internal stop)      :: 22 of 137
            Pseudo Genes (multiple problems)  :: 40 of 137
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:16:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 14514
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVWC01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..14514
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     gene            <1..5064
                     /gene="fenC"
                     /locus_tag="C6372_RS19505"
                     /old_locus_tag="C6372_19500"
     CDS             <1..5064
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: PCP (92-161). E-value: 4.6e-26. Score:
                     82.8. Matches aSDomain: nrpspksdomains_C6372_RS19505_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (175-463). E-value:
                     3.5e-110. Score: 359.6. Matches aSDomain:
                     nrpspksdomains_C6372_RS19505_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (629-1035). E-value:
                     1.8e-102. Score: 334.9. Matches aSDomain:
                     nrpspksdomains_C6372_RS19505_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1143-1204). E-value: 1.1e-21.
                     Score: 68.7. Matches aSDomain:
                     nrpspksdomains_C6372_RS19505_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (1216-1526). E-value:
                     7.4e-148. Score: 485.5. Matches aSDomain:
                     nrpspksdomains_C6372_RS19505_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1534-1679). E-value: 4.9e-44.
                     Score: 141.8. Matches aSDomain:
                     nrpspksdomains_C6372_RS19505_TIGR01720.1"
                     /codon_start=1
                     /gene="fenC"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389716.2"
                     /locus_tag="C6372_RS19505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_19500"
                     /product="fengycin non-ribosomal peptide synthetase FenC"
                     /protein_id="WP_106295895.1"
                     /sec_met_domain="PP-binding (E-value: 1.2e-17, bitscore:
                     52.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 4.7e-100, bitscore:
                     322.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.3e-113, bitscore:
                     366.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AALRSIEGVREAAVTVRTESGEAELCAYAEGLGRNEVRKQLEILL
                     PGYMIPAHIIEMEQWPVTPSGKLDRKALPAPDGAADREIYTAPRNLTEMKLSQLWEEVL
                     KSGPVGIHDNFFDRGGHSLKATALVSRIAKEFGVQVPLKDVFAHPTVEGLASVISEGTE
                     SPYEAIKPTEKRETYPVSSAQKRMYVLQQLEDGGTGYNMPAVLELEGKLDLTRLDAVFK
                     KLIKRHESLRTSFTTDADGEPVQRIHEEVPFTFRTSVLGGQTEQEAAAAFIQPFDLSQA
                     PLFRAGVVKVSDGRHLLLVDMHHIISDGVSVNTLIREFGELYANQELPLLHIQYKDYAV
                     WQEAFKKGDTYKTQEAYWLKQLEGELPVLDLPADYARPPVRSFAGDQVSFTLDQELTAG
                     LHKLARENGSTLYMVLLAAYTALLARLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLA
                     LRARPEGGKPFAQFLQEVRETALEAYEHQDYPFEELVDKLGVTRDMSRNPVFDAMFILQ
                     NMDKQDIHLGDIKARPANVIHQISVFDMTLMAAESDGVIKCDMEFSIDVFMRTTIERWT
                     AHFTEFLRAATSNPNTTLSQVDILSEKEKQKMLIELNKTHVECSQTDTVFHRMFEKRAE
                     ETPEHIAVIDGEKQISYRHLNEKANRLARTLQEKGKETQPIVAVLAERSIDAIVGILAV
                     MKAGGVYIPIDSHYPKARVEYLLKDSGAEILLLQNEVKHLIAGSDIGDISRISLDDESF
                     YEAKRCNLSSSPAPEDSAYIIYTSGTTGAPKGVIVTHRNFAHAVLAWRSIYQLDQMPVR
                     LLQMASFSFDVFSGDLARTLANGGTLVICPDETRLEPAELYALMNRQRITIMESTPALI
                     VPFMEYVYRNQLSLPDLDILILGSDMVKAHDFKTLADRFGNKMRLINSYGVTEATIDSS
                     YYEMNMGEEYSGDSVPIGIPLPNVKLYVLSQTDQIQPIGIAGELCIGGAGVAKGYHGKF
                     ELTEKKFTENPFVPGERLYRTGDLACWLPNGTLRLLGRIDHQVKINGYRIETEEIESVL
                     LQTGLVNEAVVAVQNDTNGQARLAAYILPSDADTTALRGALSKMLPAYMVPAHIIPLET
                     MPLTLNGKLDRRALPAPNETVSRPYTAPVNELQGMTAQIWEDVLSVSRVGIHDSFFELG
                     GDSIKALQVSARLAAEGWSMTIQDLFRYPTVHELSNHITPLISQAEQKPIEGEADLTPI
                     QSRFFDQRHAFHDHYNQSVMLFSEKGFHADALRQALRKLTEHHDALRMVFTQDHTGRVV
                     QYNRGIQITENELFGFHLADWTKEQAKGTLLKEKFAAEEIVLQSNMNVKEGPLLQAGLF
                     KTREGDHLLITIHHLAVDGVSWRILLEDLAAAYQQSSEQTEIKLPPKSDSYLSYANGLA
                     QIAGSRQLLSEITYWQTILDAHNVFLPKDMAESDRHQSSAETAAFVLASDWTKKLLFET
                     QQAYGTDANELLLTALGMALYEWSGHEQIVISAEGHGREGHVPNIDISRTVGWFTSIYP
                     ILLDMSAPHSSEDQLGYRIKGTKDRLRRVPHKGTGYGLLVQKGAIQHKEPEISFNYLGQ
                     FSEGESSDLFQLSSYQPRYEIAGEREREYELDITALITDGRLQVKAVYTRVFHENTIQC
                     LMDSFHSHLIEIIEHCTKKKEREKTLSDFSNKELTPSALSSIENLVKDL"
     source          1..14514
                     /collection_date="2005"
                     /db_xref="taxon:260554"
                     /geo_loc_name="China: Qinghai, Qinghai lake"
                     /isolation_source="salt lake"
                     /mol_type="genomic DNA"
                     /organism="Bacillus halotolerans"
                     /strain="DGL6"
                     /submitter_seqid="NODE_14_length_14514_cov_36.3066"
     cand_cluster    1..14514
                     /SMILES="NC(CCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(O)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14514
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:>14514](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <1..>14514
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS_motif       199..225
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0001"
                     /evalue="1.30E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="C6372_RS19505"
                     /protein_end="74"
                     /protein_start="65"
                     /score="5.4"
                     /tool="antismash"
                     /translation="GKLDRKALP"
     aSDomain        280..486
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19505_PCP.1"
                     /evalue="4.60E-26"
                     /label="C6372_RS19505_PCP.1"
                     /locus_tag="C6372_RS19505"
                     /protein_end="161"
                     /protein_start="92"
                     /score="82.8"
                     /tool="antismash"
                     /translation="EMKLSQLWEEVLKSGPVGIHDNFFDRGGHSLKATALVSRIAKEFG
                     VQVPLKDVFAHPTVEGLASVISEG"
     aSDomain        529..1392
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19505_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.50E-110"
                     /label="C6372_RS19505_Condensation_LCL.1"
                     /locus_tag="C6372_RS19505"
                     /protein_end="463"
                     /protein_start="175"
                     /score="359.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="ETYPVSSAQKRMYVLQQLEDGGTGYNMPAVLELEGKLDLTRLDAV
                     FKKLIKRHESLRTSFTTDADGEPVQRIHEEVPFTFRTSVLGGQTEQEAAAAFIQPFDLS
                     QAPLFRAGVVKVSDGRHLLLVDMHHIISDGVSVNTLIREFGELYANQELPLLHIQYKDY
                     AVWQEAFKKGDTYKTQEAYWLKQLEGELPVLDLPADYARPPVRSFAGDQVSFTLDQELT
                     AGLHKLARENGSTLYMVLLAAYTALLARLSGQEDIIVGSPIAGRPHKDLEPILGMFVNT
                     LALRARP"
     aSModule        529..5040
                     /complete
                     /domains="nrpspksdomains_C6372_RS19505_Condensation_LCL.1"
                     /domains="nrpspksdomains_C6372_RS19505_AMP-binding.1"
                     /domains="nrpspksdomains_C6372_RS19505_PCP.2"
                     /domains="nrpspksdomains_C6372_RS19505_Epimerization.1"
                     /domains="nrpspksdomains_C6372_RS19505_TIGR01720.1"
                     /locus_tags="C6372_RS19505"
                     /monomer_pairings="Orn -> D-Orn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       601..708
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0002"
                     /evalue="1.60E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="C6372_RS19505"
                     /protein_end="235"
                     /protein_start="199"
                     /score="49.5"
                     /tool="antismash"
                     /translation="YNMPAVLELEGKLDLTRLDAVFKKLIKRHESLRTSF"
     CDS_motif       907..972
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0003"
                     /evalue="5.20E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="C6372_RS19505"
                     /protein_end="323"
                     /protein_start="301"
                     /score="28.6"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNTLIREFGELY"
     CDS_motif       1003..1032
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0004"
                     /evalue="3.70E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="C6372_RS19505"
                     /protein_end="343"
                     /protein_start="333"
                     /score="13.2"
                     /tool="antismash"
                     /translation="QYKDYAVWQE"
     CDS_motif       1294..1383
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0005"
                     /evalue="1.90E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="C6372_RS19505"
                     /protein_end="460"
                     /protein_start="430"
                     /score="49.1"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLALR"
     CDS_motif       1432..1551
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0006"
                     /evalue="5.20E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="C6372_RS19505"
                     /protein_end="516"
                     /protein_start="476"
                     /score="70.3"
                     /tool="antismash"
                     /translation="RETALEAYEHQDYPFEELVDKLGVTRDMSRNPVFDAMFIL"
     aSDomain        1891..3108
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19505_AMP-binding.1"
                     /evalue="1.80E-102"
                     /label="C6372_RS19505_AMP-binding.1"
                     /locus_tag="C6372_RS19505"
                     /protein_end="1035"
                     /protein_start="629"
                     /score="334.9"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="FEKRAEETPEHIAVIDGEKQISYRHLNEKANRLARTLQEKGKETQ
                     PIVAVLAERSIDAIVGILAVMKAGGVYIPIDSHYPKARVEYLLKDSGAEILLLQNEVKH
                     LIAGSDIGDISRISLDDESFYEAKRCNLSSSPAPEDSAYIIYTSGTTGAPKGVIVTHRN
                     FAHAVLAWRSIYQLDQMPVRLLQMASFSFDVFSGDLARTLANGGTLVICPDETRLEPAE
                     LYALMNRQRITIMESTPALIVPFMEYVYRNQLSLPDLDILILGSDMVKAHDFKTLADRF
                     GNKMRLINSYGVTEATIDSSYYEMNMGEEYSGDSVPIGIPLPNVKLYVLSQTDQIQPIG
                     IAGELCIGGAGVAKGYHGKFELTEKKFTENPFVPGERLYRTGDLACWLPNGTLRLLGRI
                     DHQVKIN"
     CDS_motif       2077..2118
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0007"
                     /evalue="1.00E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="C6372_RS19505"
                     /protein_end="705"
                     /protein_start="691"
                     /score="15.6"
                     /tool="antismash"
                     /translation="LAVMKAGGVYIPID"
     CDS_motif       2314..2373
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0008"
                     /evalue="2.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="C6372_RS19505"
                     /protein_end="790"
                     /protein_start="770"
                     /score="29.4"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGAPKGVIVTH"
     CDS_motif       2902..2991
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0009"
                     /evalue="6.70E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="C6372_RS19505"
                     /protein_end="996"
                     /protein_start="966"
                     /score="40.8"
                     /tool="antismash"
                     /translation="PIGIAGELCIGGAGVAKGYHGKFELTEKKF"
     CDS_motif       3076..3138
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0010"
                     /evalue="6.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="C6372_RS19505"
                     /protein_end="1045"
                     /protein_start="1024"
                     /score="31.2"
                     /tool="antismash"
                     /translation="LGRIDHQVKINGYRIETEEIE"
     CDS_motif       3343..3369
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0011"
                     /evalue="1.30E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="C6372_RS19505"
                     /protein_end="1122"
                     /protein_start="1113"
                     /score="5.4"
                     /tool="antismash"
                     /translation="GKLDRRALP"
     aSDomain        3433..3615
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19505_PCP.2"
                     /evalue="1.10E-21"
                     /label="C6372_RS19505_PCP.2"
                     /locus_tag="C6372_RS19505"
                     /protein_end="1204"
                     /protein_start="1143"
                     /score="68.7"
                     /tool="antismash"
                     /translation="AQIWEDVLSVSRVGIHDSFFELGGDSIKALQVSARLAAEGWSMTI
                     QDLFRYPTVHELSNHI"
     aSDomain        3652..4581
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19505_Epimerization.1"
                     /evalue="7.40E-148"
                     /label="C6372_RS19505_Epimerization.1"
                     /locus_tag="C6372_RS19505"
                     /protein_end="1526"
                     /protein_start="1216"
                     /score="485.5"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLAVDG"
                     /tool="antismash"
                     /translation="EGEADLTPIQSRFFDQRHAFHDHYNQSVMLFSEKGFHADALRQAL
                     RKLTEHHDALRMVFTQDHTGRVVQYNRGIQITENELFGFHLADWTKEQAKGTLLKEKFA
                     AEEIVLQSNMNVKEGPLLQAGLFKTREGDHLLITIHHLAVDGVSWRILLEDLAAAYQQS
                     SEQTEIKLPPKSDSYLSYANGLAQIAGSRQLLSEITYWQTILDAHNVFLPKDMAESDRH
                     QSSAETAAFVLASDWTKKLLFETQQAYGTDANELLLTALGMALYEWSGHEQIVISAEGH
                     GREGHVPNIDISRTVGWFTSIYPILLDMS"
     CDS_motif       3760..3828
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0012"
                     /evalue="4.40E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="C6372_RS19505"
                     /protein_end="1275"
                     /protein_start="1252"
                     /score="19.1"
                     /tool="antismash"
                     /translation="HADALRQALRKLTEHHDALRMVF"
     CDS_motif       4054..4119
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0013"
                     /evalue="6.20E-12"
                     /label="NRPS-E2"
                     /locus_tag="C6372_RS19505"
                     /protein_end="1372"
                     /protein_start="1350"
                     /score="37.6"
                     /tool="antismash"
                     /translation="LLITIHHLAVDGVSWRILLEDL"
     CDS_motif       4522..4572
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0014"
                     /evalue="6.20E-09"
                     /label="NRPS-E5"
                     /locus_tag="C6372_RS19505"
                     /protein_end="1523"
                     /protein_start="1506"
                     /score="27.8"
                     /tool="antismash"
                     /translation="DISRTVGWFTSIYPILL"
     aSDomain        4606..5040
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19505_TIGR01720.1"
                     /evalue="4.90E-44"
                     /label="C6372_RS19505_TIGR01720.1"
                     /locus_tag="C6372_RS19505"
                     /protein_end="1679"
                     /protein_start="1534"
                     /score="141.8"
                     /tool="antismash"
                     /translation="LGYRIKGTKDRLRRVPHKGTGYGLLVQKGAIQHKEPEISFNYLGQ
                     FSEGESSDLFQLSSYQPRYEIAGEREREYELDITALITDGRLQVKAVYTRVFHENTIQC
                     LMDSFHSHLIEIIEHCTKKKEREKTLSDFSNKELTPSALSS"
     CDS_motif       4627..4680
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19505_0015"
                     /evalue="6.70E-08"
                     /label="NRPS-E6"
                     /locus_tag="C6372_RS19505"
                     /protein_end="1559"
                     /protein_start="1541"
                     /score="24.9"
                     /tool="antismash"
                     /translation="TKDRLRRVPHKGTGYGLL"
     aSDomain        5090..5176
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19510_NRPS-COM_Nterm.1"
                     /evalue="7.20E-17"
                     /label="C6372_RS19510_NRPS-COM_Nterm.1"
                     /locus_tag="C6372_RS19510"
                     /protein_end="29"
                     /protein_start="0"
                     /score="52.3"
                     /tool="antismash"
                     /translation="MTQATQIQDIYPLSYMQEGMLFHSLLDFS"
     gene            5090..12805
                     /gene="fenD"
                     /locus_tag="C6372_RS19510"
                     /old_locus_tag="C6372_19505"
     CDS             5090..12805
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-29). E-value: 7.2e-17.
                     Score: 52.3. Matches aSDomain:
                     nrpspksdomains_C6372_RS19510_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-309). E-value:
                     7.6e-111. Score: 361.9. Matches aSDomain:
                     nrpspksdomains_C6372_RS19510_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (474-865). E-value:
                     5.1e-109. Score: 356.5. Matches aSDomain:
                     nrpspksdomains_C6372_RS19510_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (970-1036). E-value: 6e-25. Score:
                     79.2. Matches aSDomain: nrpspksdomains_C6372_RS19510_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1054-1341). E-value:
                     2.6e-104. Score: 340.4. Matches aSDomain:
                     nrpspksdomains_C6372_RS19510_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1505-1903). E-value:
                     2.3e-116. Score: 380.7. Matches aSDomain:
                     nrpspksdomains_C6372_RS19510_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2011-2078). E-value: 7.4e-21.
                     Score: 66.1. Matches aSDomain:
                     nrpspksdomains_C6372_RS19510_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (2088-2404). E-value:
                     6e-156. Score: 512.3. Matches aSDomain:
                     nrpspksdomains_C6372_RS19510_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (2414-2564). E-value: 7.5e-51.
                     Score: 164.0. Matches aSDomain:
                     nrpspksdomains_C6372_RS19510_TIGR01720.1"
                     /codon_start=1
                     /gene="fenD"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389715.1"
                     /locus_tag="C6372_RS19510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_19505"
                     /product="fengycin non-ribosomal peptide synthetase FenD"
                     /protein_id="WP_106295896.1"
                     /sec_met_domain="Condensation (E-value: 9.5e-94, bitscore:
                     301.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.8e-124, bitscore:
                     401.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.3e-17, bitscore:
                     51.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQATQIQDIYPLSYMQEGMLFHSLLDFSSKAYVEQTSFTITGSL
                     CIDSFQKSLNLLVSRYDIFRTIFIKEVPDLTGPQQVVLTNRELTVQREDLSHLKHDEQL
                     ALIEDFMQQDREKGFHLQKDPLMRLTLFDRGDSTYTCVWTHHHIIMDGWCLGIILKEFF
                     SMYDSLKNNRPVQLDSTVPYSRYIEWLGEQDQEETAAYWRDYLQEYGNTASIPKLKSRS
                     ANGEYEAANIRFSLEPAIVQKLTAAAQNWGVTLNTLFMSLWGVLLHRYNGTDDAVFGSV
                     VSGRPSAIDGIESMVGLFINTVPVRIRSAEKMAFSTLVKSVQEDTLRSEQHGYYPLYEI
                     QNSSALKQGLIDHILVFENYPVQLQQAVNRQSENDENALKLDDISMSEQTSYDLNVVIV
                     PGESFYIKFSYNAAVYEREEVLRIQGHLMQAMDCILSNPDIAVDSINIVPTEERKLIQS
                     FNETERHYPNKTLSQLFEEQALKTPDAAALRMGDECRTYRQLDERANQIAHALIEKGAG
                     SGGIVAVMMERSMDMAAALLGIWKAGGAYLPLDPSYPKERLSFLLHDSQAALLLTEEAL
                     ISSIPSGYEGSIVTSGHTTHYRTDSPDASIGELAYLIYTSGTTGRPKGVLVDHQGIANT
                     LQWRREEYGMSEGDTALHLFSYVFDGCVTSLFTPLLSGACVLLTTDNEAKDVLALRRKI
                     AQYKVSHMLIVPSLYRVLLEVLTAEDAQSVRIVTFAGEAVTPDLLETSRKICPSAELAN
                     EYGPTENSVATTILRHLNEEERITIGHPIANTKVYILQGEQLQPIGAAGELCISGAGLA
                     RGYYKRTELTEKAFTDHPFLKGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIRGYRIEL
                     SEIETVLRQASGVKEAAVLARDVSDEEKELVAYIVPEKGNGLPNLHQHLAGTLPSYMIP
                     ASIIKITQMPLTSSGKLDRSALPEPENTTSLTYMPPQTLMETELARIWEEVLNKNQIGI
                     RDDFFQLGGQSLKAATLVSRIHKRLNIELPLSDVFSYPTVESMAAKLMSLHEHAFTQIE
                     PADFRDVYPLSFSQKRLYALYQLADDSTGYNMPAVLELRGHLDRGRLRKVLTELVNRHE
                     SLRTAFELNNGEPVQKIHPALTADLKELEIESEQMLQSAISSFIKPFDLTAGPLFRASL
                     ISLEKERAYLLLDMHHIIADGISMSTLVQEFTDLYCGKELPALNLHYKDFAVWQQEKFP
                     ETHYSKQEAYWLKQLGGSLPVLDLPLDKTRPLLPDFSGGTFEVNIDKRTAEELHRLMFE
                     TGTTMYMLLLAVYSIMLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNTLAMRCQPEG
                     RKTFSSYLQEIRELALTAYEHQDYPFEELVNKLETKREVNRNPLFDAMLVLQNSEDFRF
                     EVPGLSISSVTPSHNVSKFDLTLHAEEHSDGIRCRFEYSTALFEEETIARWASHFIELV
                     KGITSDIHRKLSEMQLLSAPARELLLETMGQYADYPRDESIVRLFEKQAAEHPEHTAVV
                     CDHIRLTYRDLNEKAERTAAMLMKQGVRSGDIIGLMFDRSPDMVIGVLSILKAGGAYLP
                     IDPEYPQERISFMLNDSGARILLTEHGHNKPADYHGQILYLNDAENELISPDLKAQETL
                     ADQPAYVIYTSGTTGQPKGVVVEHRNVISLLKHQDLPFDFGSEDVWTLFHSYCFDFSVW
                     EMFGALLNGSTLVVVSRETARDPNAFRLLLKNEGVTVLNQTPTAFYGLIHEEENHTDRL
                     HVRYVIFGGEALQPGMLVTWNEKYPDTDLINMYGITETTVHVTYKKLSSADIEKNKSNI
                     GKPLATLQAYVMDAHMNLQPTGVPGELYIGGEGVARGYLNRDDLTAARFVPNPYLPGDR
                     LYRTGDLAKRLASGDLEYMGRIDDQVKVRGHRIELGEIQASLLQLPIIKEAAVITRDDE
                     QGQSAVYAYLVAEDGQVVNEADIRAALRAVLPDFMVPARLIQIDSIPLTVNGKLDQKAL
                     PEPDKRAQAENDISPRNEIEKAMADIWEELLEAEEIGVSANFFELGGDSIKALQVCARL
                     KQRGYETTVREMFEHQTLGELSARVRKAVRVIDQTPVEGELPWTPVQQWFFSQSLEVHH
                     FNQSVMLYRAERFDDIALRNVLRSLVTHHDALRIICRYKDGKPVQVNRGADLPDEELYA
                     FDLFDIRDHRSNTAGNAQGLSAEAHKQIEEMANQIQQTIRLETGPLLHAGLFKAEDGDH
                     LFLTIHHLVIDAVSWRILFEDFSIAYEQAVSGKPIVLPEKTDSYFTYAQTLADYSKSRR
                     LQREIAYWNEREDRHIERIPTDHTITSNSFKDTEVIDFELSREDTELLLTAANNAYNTE
                     TNDILLTALGLALQEWTGFDHFKISMEGHGREDYLDNIDMNRTVGWFTSIYPVWLDMSD
                     SDHTDEGERLGRHIKQTKDMLHRIPHKGAGYGVLKYINKIWESEYSDPEISFNYLGQFD
                     QDVQSKAFEISDIKTGNEISPDWERPYVLDISGAVSSGCLHMHIIYNRLQFKKQTIQAL
                     ADHFKHALENMIQHCAGKENREWSAADFTDEDLTLEDLSEIMGAVNKL"
     aSDomain        5111..6016
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19510_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="7.60E-111"
                     /label="C6372_RS19510_Condensation_DCL.1"
                     /locus_tag="C6372_RS19510"
                     /protein_end="309"
                     /protein_start="7"
                     /score="361.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="QDIYPLSYMQEGMLFHSLLDFSSKAYVEQTSFTITGSLCIDSFQK
                     SLNLLVSRYDIFRTIFIKEVPDLTGPQQVVLTNRELTVQREDLSHLKHDEQLALIEDFM
                     QQDREKGFHLQKDPLMRLTLFDRGDSTYTCVWTHHHIIMDGWCLGIILKEFFSMYDSLK
                     NNRPVQLDSTVPYSRYIEWLGEQDQEETAAYWRDYLQEYGNTASIPKLKSRSANGEYEA
                     ANIRFSLEPAIVQKLTAAAQNWGVTLNTLFMSLWGVLLHRYNGTDDAVFGSVVSGRPSA
                     IDGIESMVGLFINTVPVRIRS"
     aSModule        5111..8197
                     /complete
                     /domains="nrpspksdomains_C6372_RS19510_Condensation_DCL.1"
                     /domains="nrpspksdomains_C6372_RS19510_AMP-binding.1"
                     /domains="nrpspksdomains_C6372_RS19510_PCP.1"
                     /locus_tags="C6372_RS19510"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5120..5161
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0001"
                     /evalue="1.30E-04"
                     /label="C1_DCL_004-017"
                     /locus_tag="C6372_RS19510"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.1"
                     /tool="antismash"
                     /translation="YPLSYMQEGMLFHS"
     CDS_motif       5183..5296
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0002"
                     /evalue="1.60E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="C6372_RS19510"
                     /protein_end="69"
                     /protein_start="31"
                     /score="46.1"
                     /tool="antismash"
                     /translation="AYVEQTSFTITGSLCIDSFQKSLNLLVSRYDIFRTIFI"
     CDS_motif       5522..5587
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0003"
                     /evalue="2.50E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="C6372_RS19510"
                     /protein_end="166"
                     /protein_start="144"
                     /score="35.9"
                     /tool="antismash"
                     /translation="HHHIIMDGWCLGIILKEFFSMY"
     CDS_motif       5912..6007
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0004"
                     /evalue="9.00E-20"
                     /label="C5_DCL_263-294"
                     /locus_tag="C6372_RS19510"
                     /protein_end="306"
                     /protein_start="274"
                     /score="63.1"
                     /tool="antismash"
                     /translation="DAVFGSVVSGRPSAIDGIESMVGLFINTVPVR"
     CDS_motif       6056..6172
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0005"
                     /evalue="8.20E-21"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="C6372_RS19510"
                     /protein_end="361"
                     /protein_start="322"
                     /score="66.5"
                     /tool="antismash"
                     /translation="QEDTLRSEQHGYYPLYEIQNSSALKQGLIDHILVFENYP"
     aSDomain        6512..7684
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19510_AMP-binding.1"
                     /evalue="5.10E-109"
                     /label="C6372_RS19510_AMP-binding.1"
                     /locus_tag="C6372_RS19510"
                     /protein_end="865"
                     /protein_start="474"
                     /score="356.5"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FEEQALKTPDAAALRMGDECRTYRQLDERANQIAHALIEKGAGSG
                     GIVAVMMERSMDMAAALLGIWKAGGAYLPLDPSYPKERLSFLLHDSQAALLLTEEALIS
                     SIPSGYEGSIVTSGHTTHYRTDSPDASIGELAYLIYTSGTTGRPKGVLVDHQGIANTLQ
                     WRREEYGMSEGDTALHLFSYVFDGCVTSLFTPLLSGACVLLTTDNEAKDVLALRRKIAQ
                     YKVSHMLIVPSLYRVLLEVLTAEDAQSVRIVTFAGEAVTPDLLETSRKICPSAELANEY
                     GPTENSVATTILRHLNEEERITIGHPIANTKVYILQGEQLQPIGAAGELCISGAGLARG
                     YYKRTELTEKAFTDHPFLKGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIR"
     CDS_motif       6698..6739
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0006"
                     /evalue="2.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="C6372_RS19510"
                     /protein_end="550"
                     /protein_start="536"
                     /score="17.6"
                     /tool="antismash"
                     /translation="LGIWKAGGAYLPLD"
     CDS_motif       6917..6976
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0007"
                     /evalue="1.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="C6372_RS19510"
                     /protein_end="629"
                     /protein_start="609"
                     /score="29.8"
                     /tool="antismash"
                     /translation="AYLIYTSGTTGRPKGVLVDH"
     CDS_motif       7349..7381
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0008"
                     /evalue="1.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="C6372_RS19510"
                     /protein_end="764"
                     /protein_start="753"
                     /score="5.7"
                     /tool="antismash"
                     /translation="EYGPTENSVAT"
     CDS_motif       7478..7567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0009"
                     /evalue="3.10E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="C6372_RS19510"
                     /protein_end="826"
                     /protein_start="796"
                     /score="45.0"
                     /tool="antismash"
                     /translation="PIGAAGELCISGAGLARGYYKRTELTEKAF"
     CDS_motif       7649..7714
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0010"
                     /evalue="1.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="C6372_RS19510"
                     /protein_end="875"
                     /protein_start="853"
                     /score="36.3"
                     /tool="antismash"
                     /translation="YIGRFDDQVKIRGYRIELSEIE"
     aSDomain        8000..8197
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19510_PCP.1"
                     /evalue="6.00E-25"
                     /label="C6372_RS19510_PCP.1"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1036"
                     /protein_start="970"
                     /score="79.2"
                     /tool="antismash"
                     /translation="ETELARIWEEVLNKNQIGIRDDFFQLGGQSLKAATLVSRIHKRLN
                     IELPLSDVFSYPTVESMAAKL"
     aSDomain        8252..9112
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19510_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.60E-104"
                     /label="C6372_RS19510_Condensation_LCL.1"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1341"
                     /protein_start="1054"
                     /score="340.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIADG"
                     /tool="antismash"
                     /translation="VYPLSFSQKRLYALYQLADDSTGYNMPAVLELRGHLDRGRLRKVL
                     TELVNRHESLRTAFELNNGEPVQKIHPALTADLKELEIESEQMLQSAISSFIKPFDLTA
                     GPLFRASLISLEKERAYLLLDMHHIIADGISMSTLVQEFTDLYCGKELPALNLHYKDFA
                     VWQQEKFPETHYSKQEAYWLKQLGGSLPVLDLPLDKTRPLLPDFSGGTFEVNIDKRTAE
                     ELHRLMFETGTTMYMLLLAVYSIMLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNTL
                     AMRCQP"
     aSModule        8252..12781
                     /complete
                     /domains="nrpspksdomains_C6372_RS19510_Condensation_LCL.1"
                     /domains="nrpspksdomains_C6372_RS19510_AMP-binding.2"
                     /domains="nrpspksdomains_C6372_RS19510_PCP.2"
                     /domains="nrpspksdomains_C6372_RS19510_Epimerization.1"
                     /domains="nrpspksdomains_C6372_RS19510_TIGR01720.1"
                     /locus_tags="C6372_RS19510"
                     /monomer_pairings="Thr -> D-Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       8321..8428
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0011"
                     /evalue="6.70E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1113"
                     /protein_start="1077"
                     /score="53.9"
                     /tool="antismash"
                     /translation="YNMPAVLELRGHLDRGRLRKVLTELVNRHESLRTAF"
     CDS_motif       8627..8692
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0012"
                     /evalue="1.50E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1201"
                     /protein_start="1179"
                     /score="30.3"
                     /tool="antismash"
                     /translation="MHHIIADGISMSTLVQEFTDLY"
     CDS_motif       8723..8758
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0013"
                     /evalue="2.70E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1223"
                     /protein_start="1211"
                     /score="13.6"
                     /tool="antismash"
                     /translation="HYKDFAVWQQEK"
     CDS_motif       9014..9103
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0014"
                     /evalue="8.90E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1338"
                     /protein_start="1308"
                     /score="53.4"
                     /tool="antismash"
                     /translation="DIVVGSPAAGRPHADLERVIGMFVNTLAMR"
     CDS_motif       9152..9271
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0015"
                     /evalue="1.70E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1394"
                     /protein_start="1354"
                     /score="49.3"
                     /tool="antismash"
                     /translation="RELALTAYEHQDYPFEELVNKLETKREVNRNPLFDAMLVL"
     aSDomain        9605..10798
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19510_AMP-binding.2"
                     /evalue="2.30E-116"
                     /label="C6372_RS19510_AMP-binding.2"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1903"
                     /protein_start="1505"
                     /score="380.7"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEKQAAEHPEHTAVVCDHIRLTYRDLNEKAERTAAMLMKQGVRSG
                     DIIGLMFDRSPDMVIGVLSILKAGGAYLPIDPEYPQERISFMLNDSGARILLTEHGHNK
                     PADYHGQILYLNDAENELISPDLKAQETLADQPAYVIYTSGTTGQPKGVVVEHRNVISL
                     LKHQDLPFDFGSEDVWTLFHSYCFDFSVWEMFGALLNGSTLVVVSRETARDPNAFRLLL
                     KNEGVTVLNQTPTAFYGLIHEEENHTDRLHVRYVIFGGEALQPGMLVTWNEKYPDTDLI
                     NMYGITETTVHVTYKKLSSADIEKNKSNIGKPLATLQAYVMDAHMNLQPTGVPGELYIG
                     GEGVARGYLNRDDLTAARFVPNPYLPGDRLYRTGDLAKRLASGDLEYMGRIDDQVKVR"
     CDS_motif       9791..9832
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0016"
                     /evalue="1.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1581"
                     /protein_start="1567"
                     /score="14.9"
                     /tool="antismash"
                     /translation="LSILKAGGAYLPID"
     CDS_motif       10016..10075
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0017"
                     /evalue="1.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1662"
                     /protein_start="1642"
                     /score="32.9"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGQPKGVVVEH"
     CDS_motif       10454..10477
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0018"
                     /evalue="2.50E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1796"
                     /protein_start="1788"
                     /score="2.0"
                     /tool="antismash"
                     /translation="YGITETTV"
     CDS_motif       10592..10681
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0019"
                     /evalue="2.30E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1864"
                     /protein_start="1834"
                     /score="55.0"
                     /tool="antismash"
                     /translation="PTGVPGELYIGGEGVARGYLNRDDLTAARF"
     CDS_motif       10763..10828
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0020"
                     /evalue="8.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="C6372_RS19510"
                     /protein_end="1913"
                     /protein_start="1891"
                     /score="37.1"
                     /tool="antismash"
                     /translation="YMGRIDDQVKVRGHRIELGEIQ"
     aSDomain        11123..11323
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19510_PCP.2"
                     /evalue="7.40E-21"
                     /label="C6372_RS19510_PCP.2"
                     /locus_tag="C6372_RS19510"
                     /protein_end="2078"
                     /protein_start="2011"
                     /score="66.1"
                     /tool="antismash"
                     /translation="EKAMADIWEELLEAEEIGVSANFFELGGDSIKALQVCARLKQRGY
                     ETTVREMFEHQTLGELSARVRK"
     aSDomain        11354..12301
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19510_Epimerization.1"
                     /evalue="6.00E-156"
                     /label="C6372_RS19510_Epimerization.1"
                     /locus_tag="C6372_RS19510"
                     /protein_end="2404"
                     /protein_start="2088"
                     /score="512.3"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVIDA"
                     /tool="antismash"
                     /translation="EGELPWTPVQQWFFSQSLEVHHFNQSVMLYRAERFDDIALRNVLR
                     SLVTHHDALRIICRYKDGKPVQVNRGADLPDEELYAFDLFDIRDHRSNTAGNAQGLSAE
                     AHKQIEEMANQIQQTIRLETGPLLHAGLFKAEDGDHLFLTIHHLVIDAVSWRILFEDFS
                     IAYEQAVSGKPIVLPEKTDSYFTYAQTLADYSKSRRLQREIAYWNEREDRHIERIPTDH
                     TITSNSFKDTEVIDFELSREDTELLLTAANNAYNTETNDILLTALGLALQEWTGFDHFK
                     ISMEGHGREDYLDNIDMNRTVGWFTSIYPVWLDMS"
     CDS_motif       11369..11395
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0021"
                     /evalue="7.80E-03"
                     /label="NRPS-E1"
                     /locus_tag="C6372_RS19510"
                     /protein_end="2102"
                     /protein_start="2093"
                     /score="9.6"
                     /tool="antismash"
                     /translation="WTPVQQWFF"
     CDS_motif       11774..11839
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0022"
                     /evalue="2.20E-11"
                     /label="NRPS-E2"
                     /locus_tag="C6372_RS19510"
                     /protein_end="2250"
                     /protein_start="2228"
                     /score="35.9"
                     /tool="antismash"
                     /translation="LFLTIHHLVIDAVSWRILFEDF"
     CDS_motif       12242..12292
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0023"
                     /evalue="3.50E-08"
                     /label="NRPS-E5"
                     /locus_tag="C6372_RS19510"
                     /protein_end="2401"
                     /protein_start="2384"
                     /score="25.5"
                     /tool="antismash"
                     /translation="DMNRTVGWFTSIYPVWL"
     aSDomain        12332..12781
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19510_TIGR01720.1"
                     /evalue="7.50E-51"
                     /label="C6372_RS19510_TIGR01720.1"
                     /locus_tag="C6372_RS19510"
                     /protein_end="2564"
                     /protein_start="2414"
                     /score="164.0"
                     /tool="antismash"
                     /translation="LGRHIKQTKDMLHRIPHKGAGYGVLKYINKIWESEYSDPEISFNY
                     LGQFDQDVQSKAFEISDIKTGNEISPDWERPYVLDISGAVSSGCLHMHIIYNRLQFKKQ
                     TIQALADHFKHALENMIQHCAGKENREWSAADFTDEDLTLEDLSEI"
     CDS_motif       12353..12412
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19510_0024"
                     /evalue="4.90E-08"
                     /label="NRPS-E6"
                     /locus_tag="C6372_RS19510"
                     /protein_end="2441"
                     /protein_start="2421"
                     /score="25.3"
                     /tool="antismash"
                     /translation="TKDMLHRIPHKGAGYGVLKY"
     gene            12822..>14514
                     /locus_tag="C6372_RS19515"
                     /old_locus_tag="C6372_19510"
     CDS             12822..>14514
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (2-30). E-value: 1.2e-16.
                     Score: 51.6. Matches aSDomain:
                     nrpspksdomains_C6372_RS19515_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-305). E-value:
                     3.2e-118. Score: 386.1. Matches aSDomain:
                     nrpspksdomains_C6372_RS19515_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389714.1"
                     /locus_tag="C6372_RS19515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_19510"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_142396306.1"
                     /sec_met_domain="Condensation (E-value: 1.9e-92, bitscore:
                     297.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-25, bitscore:
                     77.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQQPEIQDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTINGQL
                     DLDRFQKSMDAVFDRYEIFRTTFIYKNVAKPRQVVLKNRPCHVHFEDISHLNEREKEHC
                     TEAFKEQDKKRGFDLQSDVLMRISVLKWAPERYVCIWSHHHILMDGWCLGIIIKDFLHI
                     YQALGEGRLPYLQPVQPYGTYIKWLMQQDREEAAEYWKKRLQHFEKASSLPKRNEQVSE
                     GELQQVTFTISERETSDLQKIAAASGATLNTVFQALWGILLQKFNRCDDAVFGSVVSGR
                     PSELEDVENIVGLFINTIPIRVQSKALSFSGLVSRMQKEMTEAEAYSYFPLYDIQAQSA
                     LKQELIDHIIVFENVPTQQEIEGLNQTGSFGFSVENFAMAEETNYGCSVKVIPGRTLFV
                     RINFHTGLYEPGIIAEIKDYLQHMISAVISDPSLPVSKMTLLDHDKTQKMVAEYNTTGA
                     VSALAPTLHGLFERQAALTPDRTALRFSGGSLTYAQLDMYANRLALRLTAHGITKESIV
                     GVLSERSPDMLTAVLAVLKAGGAYVPLDPAYPEERLSYMLKDSGAAL"
     aSDomain        12828..12911
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19515_NRPS-COM_Nterm.1"
                     /evalue="1.20E-16"
                     /label="C6372_RS19515_NRPS-COM_Nterm.1"
                     /locus_tag="C6372_RS19515"
                     /protein_end="30"
                     /protein_start="2"
                     /score="51.6"
                     /tool="antismash"
                     /translation="QQPEIQDIYPLSFMQEGMLFHSLYDEQS"
     aSDomain        12843..13736
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS19515_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="3.20E-118"
                     /label="C6372_RS19515_Condensation_DCL.1"
                     /locus_tag="C6372_RS19515"
                     /protein_end="305"
                     /protein_start="7"
                     /score="386.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILMDG"
                     /tool="antismash"
                     /translation="QDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTINGQLDLDRFQK
                     SMDAVFDRYEIFRTTFIYKNVAKPRQVVLKNRPCHVHFEDISHLNEREKEHCTEAFKEQ
                     DKKRGFDLQSDVLMRISVLKWAPERYVCIWSHHHILMDGWCLGIIIKDFLHIYQALGEG
                     RLPYLQPVQPYGTYIKWLMQQDREEAAEYWKKRLQHFEKASSLPKRNEQVSEGELQQVT
                     FTISERETSDLQKIAAASGATLNTVFQALWGILLQKFNRCDDAVFGSVVSGRPSELEDV
                     ENIVGLFINTIPIRVQS"
     CDS_motif       12852..12893
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19515_0001"
                     /evalue="3.00E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="C6372_RS19515"
                     /protein_end="24"
                     /protein_start="10"
                     /score="15.8"
                     /tool="antismash"
                     /translation="YPLSFMQEGMLFHS"
     CDS_motif       12915..13031
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19515_0002"
                     /evalue="8.30E-18"
                     /label="C2_DCL_024-062"
                     /locus_tag="C6372_RS19515"
                     /protein_end="70"
                     /protein_start="31"
                     /score="56.7"
                     /tool="antismash"
                     /translation="AYFEQASFTINGQLDLDRFQKSMDAVFDRYEIFRTTFIY"
     CDS_motif       13248..13313
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19515_0003"
                     /evalue="4.80E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="C6372_RS19515"
                     /protein_end="164"
                     /protein_start="142"
                     /score="35.1"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIIIKDFLHIY"
     CDS_motif       13359..13397
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19515_0004"
                     /evalue="2.70E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="C6372_RS19515"
                     /protein_end="192"
                     /protein_start="179"
                     /score="10.5"
                     /tool="antismash"
                     /translation="PYGTYIKWLMQQD"
     CDS_motif       13533..13583
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19515_0005"
                     /evalue="2.00E+01"
                     /label="C5_DCL_263-294"
                     /locus_tag="C6372_RS19515"
                     /protein_end="254"
                     /protein_start="237"
                     /score="-2.2"
                     /tool="antismash"
                     /translation="SDLQKIAAASGATLNTV"
     CDS_motif       13632..13727
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19515_0006"
                     /evalue="2.10E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="C6372_RS19515"
                     /protein_end="302"
                     /protein_start="270"
                     /score="61.9"
                     /tool="antismash"
                     /translation="DAVFGSVVSGRPSELEDVENIVGLFINTIPIR"
     CDS_motif       13773..13889
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19515_0007"
                     /evalue="3.20E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="C6372_RS19515"
                     /protein_end="356"
                     /protein_start="317"
                     /score="61.4"
                     /tool="antismash"
                     /translation="QKEMTEAEAYSYFPLYDIQAQSALKQELIDHIIVFENVP"
     CDS_motif       14271..14336
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19515_0008"
                     /evalue="1.90E+01"
                     /label="C5_dual_260-291"
                     /locus_tag="C6372_RS19515"
                     /protein_end="505"
                     /protein_start="483"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="RFSGGSLTYAQLDMYANRLALR"
     CDS_motif       14415..14456
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS19515_0009"
                     /evalue="9.60E-07"
                     /label="NRPS-A_a2"
                     /locus_tag="C6372_RS19515"
                     /protein_end="545"
                     /protein_start="531"
                     /score="21.7"
                     /tool="antismash"
                     /translation="LAVLKAGGAYVPLD"
ORIGIN
        1 gcggcgctca gaagcattga aggtgtgcgg gaagcggctg taaccgttcg tacagaaagc
       61 ggcgaggcgg aattatgtgc gtatgcggaa ggactcggca gaaatgaagt gcgcaagcag
      121 cttgagattt tgcttccggg ctacatgatc cctgctcata tcattgagat ggaacaatgg
      181 ccggttaccc cgagcggaaa gctcgaccga aaagcgctgc ctgctcctga cggagcggca
      241 gatcgggaaa tctacacagc gccgagaaac ctgacagaga tgaagctttc ccagctgtgg
      301 gaggaagtgc tgaaaagcgg acctgtcggc attcacgaca acttttttga ccggggcggc
      361 cattccttaa aagccaccgc gcttgtctcc cggatcgcca aggaattcgg cgtccaagtg
      421 ccgctgaagg atgtgtttgc ccatccgacg gtagaaggtt tggcttctgt catcagcgaa
      481 ggaacggaaa gtccgtatga agccattaag ccaactgaaa aacgcgagac ctacccggtt
      541 tcctccgccc aaaagcggat gtatgtgctc cagcagctgg aggatggggg cacaggctac
      601 aatatgccgg cagtcttgga gctggaagga aagctggatc ttacaagatt ggatgccgta
      661 ttcaaaaagc tgatcaaacg ccacgagtca ctgcgcacgt cctttacaac ggacgcagac
      721 ggtgagcctg ttcagcgcat ccatgaagaa gtgccgttta cattccgcac atctgtgctc
      781 ggcggacaaa ctgaacagga agccgcggca gcgtttatcc agccgtttga tctcagccaa
      841 gctccgttgt tccgagcggg ggtcgtcaag gtatcagacg ggcggcatct attactggtc
      901 gatatgcatc acattatttc agatggtgtt tcagtcaata cgctcattcg ggaattcggg
      961 gagctgtacg ccaatcaaga gctacctctg cttcacattc aatataaaga ctatgccgta
     1021 tggcaggagg cctttaaaaa aggagacacg tacaagacgc aggaggcgta ctggctgaag
     1081 cagctcgaag gcgagctgcc cgtactggac ctgccggctg attacgcccg gccgccggtg
     1141 cgaagcttcg cgggtgatca agtctcattt acgcttgatc aagaactcac agccgggctt
     1201 cacaaactcg cacgggagaa cggaagcacc ctgtacatgg tgctcctggc agcttacaca
     1261 gcgttattgg cgcgcttaag cggacaggaa gacatcatcg tcgggtcacc aattgccgga
     1321 cgtcctcaca aagaccttga gccgatactt ggaatgttcg tcaatacgct ggcgcttcgg
     1381 gcacgcccgg agggcgggaa gccgtttgcg caatttttgc aggaagtgcg cgagaccgcc
     1441 ttggaagctt acgaacatca ggattatccg ttcgaagagc ttgtcgacaa gctcggagtg
     1501 acaagggata tgagccgaaa tccagtgttt gatgcgatgt ttattcttca aaatatggac
     1561 aaacaagaca ttcatcttgg agacataaaa gcccggcctg caaatgtcat tcatcaaatt
     1621 tctgtatttg acatgacgtt gatggcggct gaatcagatg gagtcatcaa atgtgacatg
     1681 gaatttagta tcgatgtatt tatgagaacg acaattgaac gctggacagc tcattttacc
     1741 gaatttttgc gtgctgccac gtcaaatcct aatacgactc tttcacaagt ggatatactc
     1801 agcgaaaaag aaaaacaaaa gatgttgata gaactcaaca aaacccacgt tgaatgttct
     1861 caaactgata ccgtttttca tcgcatgttt gaaaagaggg ctgaagagac accggagcat
     1921 attgctgtta ttgacggtga aaaacagatc agctatcgcc atctcaacga aaaagccaat
     1981 cgtctggcgc gtacactgca agaaaaagga aaagagacgc agccaatcgt tgctgtttta
     2041 gcggagcgat ccattgatgc tattgttggc attttagctg ttatgaaagc cggcggcgtg
     2101 tatattccga tagattctca ttatccaaaa gcccgggttg aatatcttct caaagacagc
     2161 ggggctgaaa ttcttctttt acagaatgaa gtaaagcatt tgattgcagg ctcagatata
     2221 ggtgatattt ctcgcattag tcttgatgat gaaagtttct atgaagcaaa aagatgcaac
     2281 ctttcttcat ctcctgcccc ggaggactcg gcatatatca tttatacgtc aggaacaacc
     2341 ggtgcgccta aaggcgttat cgttacgcac cgcaactttg ctcatgctgt tcttgcatgg
     2401 cgcagcatat atcagctcga tcaaatgcct gtcaggctgc ttcaaatggc gagcttttcc
     2461 tttgatgtct tttcaggaga cttggcgagg acattggcca acggagggac tctagtcatt
     2521 tgtcctgatg aaacaaggct tgaacctgct gaattatatg cattgatgaa ccgccagcgt
     2581 atcacgatca tggagtcaac accggcactc attgtcccat ttatggaata tgtttaccgc
     2641 aaccagctta gtcttcctga cttagacatc cttattcttg gttcggatat ggtgaaagcc
     2701 catgatttca aaacactggc ggaccgtttc ggaaacaaaa tgcgcttaat caatagttac
     2761 ggggtcacag aggccacgat cgattcaagt tactatgaaa tgaatatggg tgaagagtat
     2821 tcgggagaca gcgtaccgat cggcatcccg cttcccaatg taaaactgta cgtactcagc
     2881 cagactgacc aaatacagcc gatcggtatt gccggcgagc tttgtatcgg cggagccggc
     2941 gttgccaagg gctatcacgg aaaatttgaa ttaacggaaa agaaatttac agaaaatcca
     3001 tttgtgcccg gagaaagact gtacagaaca ggggatctgg cttgctggct tccaaacggc
     3061 actctcaggc ttcttggccg gatagatcat caagtaaaaa taaacgggta cagaatcgaa
     3121 acagaagaaa ttgaaagtgt gctcctccaa accggacttg tcaatgaagc ggttgttgcg
     3181 gttcaaaatg atacgaatgg acaggctcgt ttggcagcgt atattctgcc ttccgatgcc
     3241 gatacaacgg ctctccgcgg tgctttatca aaaatgctgc cggcatatat ggttcctgcg
     3301 catatcattc ctttggaaac tatgccgctg acattaaacg ggaagctgga cagaagagcc
     3361 ttaccggcac caaatgaaac tgtctcgcgg ccgtatactg caccggtcaa cgaattgcag
     3421 ggaatgacag cgcagatttg ggaggacgtg ctgagcgtgt cccgagttgg cattcacgac
     3481 tccttttttg agcttggagg agactctatt aaagcactgc aagtgtccgc ccggctggca
     3541 gctgaaggct ggagcatgac gatacaagat ttattccgtt atccaacagt tcatgagctg
     3601 agcaaccata tcactccact gatatctcag gcagaacaga agcctatcga aggtgaagcg
     3661 gatctcacac cgattcagag cagatttttt gatcagcgtc atgcttttca tgaccattac
     3721 aaccaatcgg tcatgctttt cagcgaaaag gggtttcatg ctgacgcgct tcgacaagcg
     3781 ctgcgcaaat tgactgagca tcatgacgcg cttcgcatgg tgtttacaca ggatcatacc
     3841 gggcgtgtcg ttcagtacaa tcgcggtatt cagattactg aaaatgaact gttcggattt
     3901 catctagccg attggacaaa agaacaggca aaaggcacac tcttgaaaga aaaatttgcc
     3961 gctgaggaaa tcgtgcttca aagcaatatg aatgtaaaag aaggaccttt gctgcaagca
     4021 ggattgttta aaacgagaga gggagaccat ttgctgatta cgatccacca tctcgctgta
     4081 gatggcgttt cttggaggat tctgcttgaa gatttagctg cagcctacca acagtcttcg
     4141 gagcaaacag agatcaaact gccgccgaaa agcgattctt atttatcata tgccaacggt
     4201 ctggcacaaa tagccgggag ccggcaattg ttatcagaaa taacatattg gcaaacgatt
     4261 ttggatgctc ataacgtttt tctgcctaag gacatggctg agtcggacag gcatcaaagc
     4321 agtgctgaaa cagctgcatt tgtattagcc agtgactgga ctaaaaaact gctgtttgaa
     4381 acgcagcaag cctatggtac tgatgccaac gaacttttgc tgaccgcttt aggaatggcg
     4441 ctttacgaat ggagcgggca cgaacaaatt gtgatcagcg ctgagggcca tggaagagaa
     4501 ggacatgttc cgaatattga tatttcacga acagtaggtt ggttcacttc tatttatcct
     4561 atccttctgg acatgagtgc accgcattca tctgaagatc agctcggtta cagaatcaaa
     4621 gggacaaagg acaggctgag aagagtgccg cacaagggaa cgggctacgg cttattagta
     4681 caaaagggag ccatacagca taaagagcct gagatcagct tcaattatct tggacaattc
     4741 agcgaaggtg agagttcaga tttgtttcaa ctgtcttctt atcagcctcg ttacgaaata
     4801 gcgggggaga gagaaagaga gtacgagctc gatattactg ctctgataac agacggacgc
     4861 ctgcaagtca aagcagtata cacccgggtg ttccacgaaa acacaattca gtgtttgatg
     4921 gacagctttc acagtcatct tatcgagatc attgagcatt gtacaaagaa aaaagaacga
     4981 gaaaaaacgc tgagcgattt cagcaacaaa gaactaacgc catccgcatt atctagcatc
     5041 gaaaatctcg ttaaagatct ttaacttttg gaaaaggtgt gtggaattga tgacgcaagc
     5101 aacacagatc caagatattt atccgttatc gtacatgcag gaagggatgc tgtttcattc
     5161 actgcttgat ttcagctcta aagcctatgt ggaacaaacc tcgtttacca ttacaggcag
     5221 cctgtgtatc gattcgtttc aaaaaagctt aaatcttctt gtttcccgat acgatatttt
     5281 cagaaccata ttcattaagg aggttccaga cctcactggg ccgcagcaag ttgtgctgac
     5341 aaaccgggaa ttgaccgtac aaagggaaga tctttctcac ctgaaacatg atgagcagct
     5401 tgctctgata gaagacttta tgcagcagga ccgggaaaaa gggtttcact tgcaaaaaga
     5461 tccgttaatg cggctcacgc tttttgatag aggagacagc acatatacat gtgtctggac
     5521 gcatcaccat atcatcatgg atggctggtg cctgggcatc atcctcaaag aattcttcag
     5581 catgtatgac tcacttaaaa ataacaggcc tgtacagctc gatagcacgg tgccgtacag
     5641 ccgttatatt gaatggctcg gagaacaaga tcaagaagaa accgctgcat actggagaga
     5701 ttatctacag gagtacggca ataccgcttc tattcccaaa ctaaaaagcc gctcagcgaa
     5761 cggggaatat gaagccgcaa atatccgttt ttctttagag ccggctatcg ttcagaaatt
     5821 gacagcagct gctcaaaatt ggggagttac attaaacact ttatttatga gtctatgggg
     5881 tgttcttcta catcgttaca acggtacgga tgacgcggtc ttcggctctg ttgtttccgg
     5941 acgtccgtca gcgattgacg ggatcgagtc aatggtcggc ttgtttatta acactgttcc
     6001 ggtgcgtatt cgatctgcag agaaaatggc attttctacg cttgtcaaat ccgtgcagga
     6061 ggatacttta cgttctgagc agcatggtta ttatccgctt tatgagattc aaaacagcag
     6121 tgctttgaag caaggattga tcgatcatat tcttgtcttt gaaaattatc ctgtacagct
     6181 tcagcaggca gtcaatagac aaagcgaaaa tgacgaaaac gcattgaagc ttgatgacat
     6241 ttctatgtca gagcaaacca gctatgacct taacgttgtc atcgttccag gtgaatcatt
     6301 ttatattaaa ttcagctaca atgccgccgt ttatgaacgt gaagaggtgc ttcggattca
     6361 ggggcacctc atgcaggcaa tggattgtat tttgtcaaat cccgatattg ctgtcgacag
     6421 catcaacatt gtgcctactg aagaacgaaa gctcattcaa tcgtttaacg aaacggagcg
     6481 ccattatcca aataaaacgc tatcccaatt atttgaggaa caggctctca aaacacctga
     6541 cgcggctgct ttgagaatgg gagatgagtg ccggacatat cggcaattag atgaaagagc
     6601 caatcagatt gcacacgccc tgatagaaaa gggagctgga tctggcggga ttgtcgctgt
     6661 gatgatggaa cggtcaatgg acatggctgc tgccctgctt ggaatttgga aagccggagg
     6721 cgcttatctg cctcttgatc caagttatcc gaaagagcgg ctttcttttc tgctgcatga
     6781 cagtcaagca gctctcttac tgacagaaga agcacttatt tcatccatcc cgtcaggcta
     6841 tgaaggcagt attgtgacat caggacatac aacacattac agaacggatt ctcctgatgc
     6901 atcgattggt gagcttgcct acctgatcta tacgtcagga acgacaggac ggccaaaagg
     6961 agtgctcgtt gaccatcaag gaattgcaaa taccttgcag tggagacggg aagagtacgg
     7021 catgagcgaa ggggatacag cacttcatct gttttcctat gttttcgacg gctgtgtgac
     7081 gagcttgttt actccgcttc tgtccggcgc atgcgtgttg ctgacaacag ataacgaagc
     7141 gaaggacgtg ctcgccctca gacggaaaat agctcaatac aaggtcagtc atatgcttat
     7201 tgttccttcc ttgtaccggg tgttattaga agtgctgact gctgaagatg cacaaagtgt
     7261 tcgtatcgtg acatttgcgg gcgaggcagt gactcccgac ctgcttgaga ccagcagaaa
     7321 gatttgtccc tccgctgaac ttgcaaatga atatggaccg acagaaaaca gtgtggcaac
     7381 aacaatcctt cgtcatctga acgaagaaga gagaatcacg atcggacacc cgatcgccaa
     7441 tacaaaagta tatattttac aaggagagca gctgcagccg ataggcgcgg cgggtgaact
     7501 gtgtatttcc ggcgcgggtc tcgcacgggg gtactataag cggacagagc taacagagaa
     7561 agcattcaca gaccatccgt tcctcaaagg ggaacgctta tatcgaaccg gagatgcagg
     7621 gcgcttcctg cctgatggca cgattgaata tattggacgt tttgatgatc aggtaaaaat
     7681 caggggatat cgcattgaat taagtgagat tgaaactgtt cttcggcaag catctggagt
     7741 gaaggaagct gcagtgctgg cccgtgatgt ttctgatgag gaaaaggaac tcgttgctta
     7801 tatcgttccg gaaaaaggaa acggccttcc gaatctgcac cagcatcttg ccggtacatt
     7861 gccgtcctat atgattcccg caagcatcat caaaatcact caaatgccgt taacatccag
     7921 cgggaagctc gaccgttccg cacttccgga accagaaaac acaactagct taacgtacat
     7981 gccgccacaa accttaatgg aaacggaact ggcacgcatt tgggaagagg tgctgaacaa
     8041 aaatcaaatc ggtattcgcg atgatttctt tcaattaggc ggacagtcct taaaagcagc
     8101 cacactcgta tcacgaatac ataaacggct gaatatcgag ctgccgctca gtgacgtttt
     8161 ttcttatccg accgtggaaa gcatggcagc caaactgatg agtttacatg agcatgcttt
     8221 tacgcagatt gaacctgcgg attttagaga tgtttatccg ctgtctttct cgcaaaaaag
     8281 attatacgct ctttaccagt tggcagatga cagcacaggt tacaacatgc cggcggtact
     8341 ggaactgcga ggacatttgg atcgcggaag attgagaaaa gttctcacag agcttgtgaa
     8401 tcggcatgaa tcattgcgta cggcatttga actgaacaac ggagagccag tgcaaaagat
     8461 tcatccggcg ctgacagctg atctgaaaga gcttgaaatt gaatcagagc aaatgctgca
     8521 gtctgcgatc tcgtccttta tcaaaccgtt tgatcttacc gcgggaccgc tttttagagc
     8581 aagcttgatt tctctcgaaa aagaaagagc ctatttgttg cttgatatgc atcacatcat
     8641 tgctgacgga atctccatga gtacactcgt ccaagaattc actgatcttt attgcggaaa
     8701 agagcttcca gctttaaatc tgcattataa ggattttgcg gtttggcagc aggagaagtt
     8761 tccggaaacg cattacagca aacaggaggc ctactggctg aagcagcttg gcggcagcct
     8821 tccagtattg gatttgccgc ttgataaaac gaggccgctt ctgcctgatt tcagcggcgg
     8881 aacatttgaa gtaaacattg ataaaagaac ggcggaagaa ctgcaccgct tgatgtttga
     8941 aacgggaacg acgatgtata tgctccttct ggctgtctat tccatcatgc tttccaaact
     9001 gagcgggcag gaggatatcg ttgtcggctc gcctgctgcc gggagaccgc acgctgatct
     9061 ggagcgagtc atcgggatgt ttgtcaatac attagctatg cgatgccagc ctgagggccg
     9121 caaaacgttc agctcttatt tgcaggaaat tcgcgaactt gctctgactg catacgagca
     9181 tcaggattat ccttttgaag agctcgtcaa taagcttgaa acgaaacggg aggtaaatcg
     9241 caatccgctg tttgacgcga tgctcgtgct tcaaaacagc gaagatttcc ggtttgaagt
     9301 gcctggttta tctatctcgt ctgtaacccc gtcacacaat gtatctaaat tcgatttgac
     9361 attacacgct gaggagcatt ccgatggcat tcgctgccgc ttcgaataca gtaccgcgct
     9421 gtttgaagaa gagaccattg caagatgggc ttcccatttt attgagctgg tgaaaggaat
     9481 aacgtctgat atccatagga agctttcgga aatgcaattg ctatctgctc cagcgcgcga
     9541 attgcttctt gaaacgatgg gtcagtatgc tgactatcca agagatgaaa gcatcgttcg
     9601 tttatttgaa aaacaagcag ctgaacatcc cgaacatacc gcagtcgtat gcgatcatat
     9661 acggctgact tatcgggacc tgaatgaaaa agcagaacgg acagcggcta tgctgatgaa
     9721 acaaggagtc cgatccgggg atatcatcgg tttaatgttt gatcgatcgc ctgatatggt
     9781 gattggcgtt ttatctattc taaaggccgg aggggcatac ttgccgattg accctgaata
     9841 tcctcaagaa cgcatcagct ttatgctgaa tgacagcggg gcgagaattc tcctgacaga
     9901 gcacggacac aacaagccgg cggattacca tgggcaaatt ttatacctga atgacgccga
     9961 aaacgaattg atttcgcctg atttgaaagc gcaagaaaca ttagcagacc agccagctta
    10021 tgtgatttat acatctggaa ccactgggca gccaaagggc gtcgttgtcg agcaccgtaa
    10081 tgtgattagt ctattgaagc atcaggacct gccttttgat tttggcagtg aggacgtgtg
    10141 gactttattt cattcatatt gctttgattt ctcagtatgg gaaatgttcg gagcgttgct
    10201 gaatggaagt acgctggttg ttgtctccag agaaacagcc cgcgatccaa acgcattccg
    10261 cctattgtta aaaaacgaag gcgtcacagt actcaatcag actccaactg ctttttacgg
    10321 actcattcat gaagaagaaa accatacgga ccgattacat gtgcgatacg ttattttcgg
    10381 cggagaagct ttacagcccg gcatgcttgt aacctggaac gagaaatacc ctgatactga
    10441 tctgatcaat atgtacggca ttactgaaac aactgtacat gtgacatata agaaattgtc
    10501 ctcagctgat atagaaaaaa ataaaagcaa tatcggaaaa ccgctggcaa cccttcaggc
    10561 ttatgtgatg gatgctcata tgaatctaca gcctacagga gttccaggag agctgtatat
    10621 tggcggagaa ggtgtagccc ggggatattt gaacagagat gatctgaccg cggcccgatt
    10681 tgtacctaat ccttatcttc cgggagacag attataccga accggagacc ttgcaaagcg
    10741 tctggcaagt ggagatctgg aatatatggg ccgcattgat gatcaagtaa aggtgagagg
    10801 acaccgcatc gagctcggtg aaatccaggc gtctctgctt cagcttccaa taattaaaga
    10861 ggctgctgtc atcacaagag atgatgaaca aggccaatcc gctgtatatg cttacttggt
    10921 tgcggaagat ggacaggtcg taaatgaagc agatatcagg gctgccctga gagccgttct
    10981 gcctgatttt atggtgcctg cccgcttgat ccaaattgac agcatcccgc tgacggttaa
    11041 cggcaagctc gaccagaaag ccctgccgga accagataag cgcgctcaag ctgagaatga
    11101 tatcagccct agaaatgaga ttgaaaaggc gatggctgac atttgggagg aactgctcga
    11161 agcggaggag ataggtgtca gcgcgaattt ctttgagctt ggaggggatt caataaaagc
    11221 gttgcaggtg tgtgcacggc tgaagcagcg aggctatgaa acgacagtgc gtgagatgtt
    11281 tgagcatcag acgcttggtg aactgtccgc ccgcgttcga aaagccgtac gcgtaattga
    11341 ccaaacgcca gtcgaaggcg agctgccttg gacacctgta cagcaatggt ttttctcaca
    11401 atcattggaa gtccatcatt ttaatcaatc tgtcatgctc taccgggctg aacggtttga
    11461 tgacattgca ctcagaaatg tactgagaag cttggtgaca catcatgacg cactgagaat
    11521 catatgccgt tacaaagatg gcaagcctgt acaggttaac agaggagcag atcttccgga
    11581 tgaggagcta tatgccttcg atctgtttga tataagagat catcgttcaa atacagccgg
    11641 aaatgcacag ggcttgtcag ccgaagcaca caaacagatt gaagaaatgg caaaccaaat
    11701 tcagcaaact attcgactgg agactggccc tttgcttcat gctggtttgt ttaaagccga
    11761 agatggagac catttgtttc tgacgatcca tcacttagtc attgatgccg tttcatggcg
    11821 cattttattt gaggattttt caattgctta cgaacaggca gtctcaggaa agcccatcgt
    11881 actgcccgaa aaaacggatt catatttcac ttatgcacaa acattggctg actattcaaa
    11941 gagccgtcgt ctgcagcgtg aaatcgcgta ttggaatgag cgggaggacc ggcatattga
    12001 gcgtattccc acagatcata cgatcacatc gaactcattc aaagatacag aagtaattga
    12061 tttcgagctg tctcgtgaag atacagaatt gctgttaact gctgcaaaca atgcatacaa
    12121 cacggaaacg aatgatatcc ttctgactgc tttaggccta gctttgcagg aatggacggg
    12181 ctttgaccat ttcaaaatca gtatggaggg ccacggcaga gaagattatc ttgacaatat
    12241 tgacatgaac agaactgtag gctggttcac ttcaatttat cctgtatggc ttgatatgag
    12301 tgattctgac catacggatg aaggtgagcg gctggggcga cacattaagc agacaaaaga
    12361 catgctgcac cgcataccgc ataaaggcgc aggctatgga gtgctgaaat atatcaacaa
    12421 gatatgggaa tctgagtaca gcgacccgga aatcagcttt aattacttag gccagtttga
    12481 tcaggatgtt caatcaaaag cttttgagat ttctgatatt aagacaggga atgaaatcag
    12541 cccggattgg gagcggcctt atgtgttaga tatcagcgga gccgtttcat caggatgcct
    12601 gcacatgcac attatttata accgtcttca atttaagaaa caaaccatac aagcattagc
    12661 cgatcatttt aaacatgcgc ttgaaaacat gattcagcat tgcgcgggca aagaaaaccg
    12721 cgaatggagt gccgctgatt ttactgatga ggatttaacg ctggaggatt taagtgagat
    12781 tatgggggcc gtcaacaaac tataggagag gagattcatt gatgccgcag caacccgaaa
    12841 tacaggatat atatcccttg tcttttatgc aggaggggat gctttttcat tcgctgtatg
    12901 atgaacagtc gagagcttat tttgaacaag cgtcttttac aatcaatggg cagcttgact
    12961 tagaccgttt ccagaaaagt atggacgctg tttttgacag gtatgaaatc tttcgaacga
    13021 cttttatcta caaaaatgta gccaaacctc gtcaggtggt gcttaaaaac cgtccttgcc
    13081 atgttcattt tgaagatatt tctcatctta atgagagaga gaaagaacat tgtacagaag
    13141 cattcaagga acaagataaa aaaaggggct ttgatcttca gtcggatgta ctgatgagaa
    13201 tatccgtttt aaaatgggcg cctgagcgtt acgtatgcat ctggagccat caccatattt
    13261 taatggacgg atggtgctta ggcatcatca ttaaagactt tctccacatt tatcaagcgc
    13321 tgggagaagg gcggcttcca tatttgcagc cagttcagcc gtacggaacg tatattaaat
    13381 ggctgatgca gcaggatcgt gaagaggcag ctgaatattg gaaaaagcgg ctgcagcatt
    13441 tcgagaaagc ttcttctttg ccaaaaagaa acgagcaagt atcagaaggt gaattacagc
    13501 aggtcacgtt taccatctct gaaagagaaa cgtccgattt gcagaaaatc gcagcagcat
    13561 ccggtgcaac gcttaacacc gttttccaag ctttgtgggg aattttgctg caaaaattca
    13621 atcgctgtga cgatgcagtg ttcggatcag tcgtctcagg caggccctct gagctggagg
    13681 atgtagaaaa tatagtcggc ctttttatca ataccatccc catccgggtc caaagcaaag
    13741 ctctttcttt ctctggcctg gtcagccgga tgcaaaagga aatgactgaa gcagaagcat
    13801 acagttattt ccctctatat gacattcaag cacagagtgc tcttaaacaa gagctcattg
    13861 atcatattat cgtgtttgaa aacgtgccga cccagcaaga aattgaagga ctaaaccaga
    13921 ctggatcgtt cggtttctca gtggaaaact ttgcgatggc ggaggaaact aattatggtt
    13981 gcagcgtcaa agtgattcca ggccgcacat tgttcgtgcg catcaatttt catacaggtt
    14041 tatatgagcc tggcataata gctgagataa aagattattt acagcatatg atttcagctg
    14101 tcatctctga tccttctctt cctgtttcaa agatgacgtt actagatcat gacaaaacac
    14161 agaaaatggt tgctgaatat aatacgacgg gagctgtttc agcgttagct ccgacgctgc
    14221 acgggctgtt tgaacgtcag gcggctttga cgccggatcg gacggcctta cgcttttctg
    14281 gcggctcgct gacttacgcg cagcttgaca tgtacgccaa taggctggca ttgcgcctta
    14341 cggcgcatgg tatcacaaag gaaagcattg ttggtgttct aagcgagcgt tcgccggaca
    14401 tgctgacagc cgttctcgcc gtattaaagg caggcggagc ttatgtgccg cttgatcctg
    14461 catatccaga ggagcggctg agctatatgc tgaaagacag cggggcagca ttgt
//
