LOCUS       NZ_PVWC01000001        21681 bp    DNA     linear   CON 05-SEP-2024
DEFINITION  Bacillus halotolerans strain DGL6 NODE_1_length_1124240_cov_38.3018,
            whole genome shotgun sequence.
ACCESSION   NZ_PVWC01000001
VERSION     NZ_PVWC01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus halotolerans
  ORGANISM  Bacillus halotolerans
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 1124240)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Genotypic and phenotypic analysis of antagonistic Bacillus spp.
            isolated from rhizosphere soil of plants in Tibet
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1124240)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAR-2018) UG, NordReet, Marienstr. 27a, Greifswald
            17489, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. A5-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 38.3x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003003575.1-RS_2024_09_05
            Annotation Date                   :: 09/05/2024 04:49:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,923
            CDSs (total)                      :: 3,840
            Genes (coding)                    :: 3,703
            CDSs (with protein)               :: 3,703
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 9, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 8, 1 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 90 of 137
            Pseudo Genes (incomplete)         :: 71 of 137
            Pseudo Genes (internal stop)      :: 22 of 137
            Pseudo Genes (multiple problems)  :: 40 of 137
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:16:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1102559
            Orig. end                         :: 1124240
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVWC01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21681
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="4"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..21681
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21681
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:>21681](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>21681
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            856..1971
                     /gene="proB"
                     /locus_tag="C6372_RS06215"
                     /old_locus_tag="C6372_06210"
     CDS             856..1971
                     /EC_number="2.7.2.11"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017359466.1"
                     /locus_tag="C6372_RS06215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06210"
                     /product="glutamate 5-kinase"
                     /protein_id="WP_106294190.1"
                     /transl_table=11
                     /translation="MTSETEMKRVVVKIGSSSLTSLHGEISIRKLEALVDQVAKLKDAG
                     YEVILVSSGAVAAGYRKLGFLQRPENPPEKQASASIGQGLLMEAYSKLFLAHGYVASQI
                     LITRSDFSDEYRYHNVRNTMNVLLERGIIPIINENDTVTVNRLKFGDNDTLAAKVAGLI
                     DADLLVILSDIDGLYDGNPRNNPKAKRVQRVSEVTPEIEACAGDTDSEVGTGGMRSKLD
                     AFKIVMASGIKGFLGQADAADILYQAVHGEAEGTYFEAEGTLPLNQKEQWIAFNSGPEG
                     EIVLSDDCSGQIADGQSHIYPDGVREIKGKFKSGAVVRLTDSHGEDIGLGIVNYSSSQL
                     ETPEKNKGMKNKAVIDPEAFVCHVDLSLPVY"
     gene            complement(2032..2934)
                     /gene="gltC"
                     /locus_tag="C6372_RS06220"
                     /old_locus_tag="C6372_06215"
     CDS             complement(2032..2934)
                     /codon_start=1
                     /gene="gltC"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389728.2"
                     /locus_tag="C6372_RS06220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06215"
                     /product="glutamate biosynthesis transcriptional regulator
                     GltC"
                     /protein_id="WP_024121635.1"
                     /transl_table=11
                     /translation="MELRQLRYFMEVAEREHVSEAADYLHVAQSAISRQIANLEEELNV
                     TLFEREGRNIKLTPIGKEFLIHVKTAMKAIDYAKEQIDEYLDPHRGTVKIGFPTSLASQ
                     LLPTVVSAFKEEYPHVEFLLRQGSYKFLIEAVRNRDIDLALLGPVPTNFPDIAGNILFT
                     EKIYALVPLNHPLAKQKTVHLIDLRNDQFVLFPEGFVLRKMAIDSCKQAGFAPLVSTEG
                     EDLDAIKGLVSAGMGVTLLPESTFAETTPRFTVKIPIEFPQVKRTVGIIKPKNRELAPS
                     AQDFYEFVIQFFSKLEQYQ"
     misc_feature    2954..2968
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            3081..7643
                     /gene="gltB"
                     /locus_tag="C6372_RS06225"
                     /old_locus_tag="C6372_06220"
     CDS             3081..7643
                     /EC_number="1.4.1.13"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0015930 - glutamate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="gltB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389727.2"
                     /locus_tag="C6372_RS06225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06220"
                     /product="glutamate synthase large subunit"
                     /protein_id="WP_106294192.1"
                     /transl_table=11
                     /translation="MTYNQMPKAQGLYRPEFEHDACGIGLYAHLRGKATHDIVKQGLQM
                     LCQLDHRGGQGSDPDTGDGAGLLVQIPDAFFKKECKDINLPEKGRYGVGMVFFSQKEDE
                     RKKIEKQINALIEQEGQVVLGWRTVPINVGKIGTVAQKSCPFVRQVFIGASSDLKDDLS
                     FERKLYVIRKQAENWGVTEGLDFYFASLSSQTIVYKGLLTPEQVDAFYSDLQDEAFVSA
                     FALVHSRFSTNTFPTWERAHPNRYLVHNGEINTLRGNINWMRAREQQFVSESFGEDLNK
                     ILPILNADGSDSSILDNAFEFFVMAGRKPAHTAMMLIPEPWTENTHMSKEKRAFYEYHS
                     SLMEPWDGPTAISFTDGKQIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIEVEQENVL
                     YKNRLEPGKMLLIDLEEGRIISDEEVKTQIATEYPYQKWLEEELVQVNPDPETREEEQF
                     TDLLTRQKAFGYTYEDIQKYLIPVIKEGKDPLGSMGNDSPLAVLSDRPQSLFNYFKQLF
                     AQVTNPPIDAIREQLVTSTMTWLGAEGDLLHPNERNVRRIKLYTPVLSNEQFYALKTIV
                     HPDLRSQKMNVLFSEDLERGLKDMFTQAEKAISQGVSLLILSDRAMNEQLTPIPPLLAV
                     SALHQHLIRKGLRTKVSIIVESGEAREVHHFAALIGYGADAVNPYLAYATYKQEIDEGR
                     LDISYEEAVSKYGKSITEGVVKVMSKMGISTVQSYRGAQIFEAVGISRDVIDRYFTGTA
                     SQLGGIDLNTIAEEAQRRHQEAYKDDYSKTLEPGSDFQWRNGGEHHAFNPKTIHTLQWA
                     CRRNDYNLFKQYTKAADEERIGFLRNLFSFDENRKPLKVEEVESAESIVKRFKTGAMSF
                     GSLSKEAHEALAIAMNRLGGKSNSGEGGEDPKRFVPDENGDDRRSAIKQIASGRFGVKS
                     HYLVNADELQIKMAQGAKPGEGGQLPGNKVYPWVADVRGSTPGVGLISPPPHHDIYSIE
                     DLAQLIHDLKNANRDARISVKLVSKAGVGTIAAGVAKATADVIVISGYDGGTGASPKTS
                     IKHTGLPWELGLAEAHQTLMLNGLRDRVVLETDGKLMTGRDVVMAALLGAEEFGFATAP
                     LVVLGCVMMRACHLDTCPVGVATQNPELRKKFMGDPDHIVNYMLFIAEEVREYMAALGF
                     KTFDEMIGRTDALNVSERAKAHWKASQLDLSTLLYQPEGVRTFQTPQNHKIDQSLDITT
                     ILPAVKDAIESGKEAGISVEINNTNRVAGTVTGSEISKRYGEEGLPEDTIKLQFTGSAG
                     QSFGAFVPKGMTLYLDGDSNDYVGKGLSGGKIIVKSPEGFNSESHDNVIIGNVAFYGAT
                     SGEAYINGRAGERFAVRNSGVNVVVEGIGDHGCEYMTGGSVVVLGDVGKNFAAGMSGGI
                     AYVLAEDVKAFKRKCNLEMILFESLEDEKEIQQVKAMLEKHAAYTNSQKAADLLEQWED
                     SVKTFIKVIPKNYKQMLASIEEQKAAGLSEEEAVMYAFEANTKPKQKKAPAGQKQAVVQ
                     "
     gene            7660..9141
                     /gene="gltD"
                     /locus_tag="C6372_RS06230"
                     /old_locus_tag="C6372_06225"
     CDS             7660..9141
                     /EC_number="1.4.1.-"
                     /GO_component="GO:0009342 - glutamate synthase complex
                     (NADPH) [Evidence IEA]"
                     /GO_function="GO:0045181 - glutamate synthase activity,
                     NAD(P)H as acceptor [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gltD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285: ferredoxin fdxC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389726.2"
                     /locus_tag="C6372_RS06230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06225"
                     /product="glutamate synthase small subunit"
                     /protein_id="WP_106294194.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.7e-27, bitscore:
                     92.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKPTGFMEIKREKPAERDPLTRLKDWKEYSAPFSEEASKRQGAR
                     CMDCGTPFCQIGADINGFTSGCPIYNLIPEWNDLVYRGRWKEALERLVKTNNFPEFTGR
                     VCPAPCEGSCTLAISDPAVSIKNIERTIIDKGFENGWIQPRIPKKRTGKKVAIVGSGPA
                     GLASADQLNQAGHSVTVFERADRAGGLLTYGIPNMKLEKGIVERRIKLLTQEGIDFVTN
                     TEIGVDITADELKEQFDSVILCTGAQKQRDLLIEGRESKGVHYAMDYLTLATKSYLDSN
                     FKDKRFIDAKGKDVIVIGGGDTGADCVATALRQKAKSVHQFGKHPKLPPARTNDNMWPE
                     QPHVFTLEYAYEEAEAKFGRDPREYSIQTKKLIADKNGKLKELHTIQMEKVKNEHGKYE
                     FRELPGTEKVWPAQLVFIAIGFEGTEQPLLKQFGVDSNNNKISAAYGDYKTNIDGVFAA
                     GDARRGQSLIVWAINEGREVAREVDRYLMGSSVLP"
     gene            complement(9197..10186)
                     /locus_tag="C6372_RS06235"
                     /old_locus_tag="C6372_06230"
     CDS             complement(9197..10186)
                     /NRPS_PKS="Domain: PKS_ER (12-324). E-value: 5.7e-43.
                     Score: 139.1. Matches aSDomain:
                     nrpspksdomains_C6372_RS06235_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389725.1"
                     /locus_tag="C6372_RS06235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06230"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_106294196.1"
                     /sec_met_domain="ADH_N (E-value: 6.1e-12, bitscore: 41.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.9e-28, bitscore:
                     93.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAVIHNGKSGLRGLAYQDLPSQNPGYGEVKVKLKTAGLNHRDLF
                     LMKNKTEQDSEFILGSDGAGIIEAVGEGVDNLAVQTEVVILPTLNWEVTDDVPPVPDIL
                     GGPSNGTLAEYVIIPSQNAVKKPSYLSWEEAGVLPLSALTAYRALFTKAQLKKGEHILI
                     PGIGSGVATYALVMAKAIGATVSVTSRSEEKRKRAIQLGADHAFDSYSNWSEHLQGQKA
                     DVILDSIGPALFSEYFDHVKPNGRIVSFGASSGDNLSFPLRSLFFPQINILGTSMGSRD
                     EFHEMLHFMEKHKLRPVLDRTYPIEQAHEAYTRMQEGSQFGNIGITID"
     aSDomain        complement(9215..10150)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS06235_PKS_ER.1"
                     /evalue="5.70E-43"
                     /label="C6372_RS06235_PKS_ER.1"
                     /locus_tag="C6372_RS06235"
                     /protein_end="324"
                     /protein_start="12"
                     /score="139.1"
                     /tool="antismash"
                     /translation="RGLAYQDLPSQNPGYGEVKVKLKTAGLNHRDLFLMKNKTEQDSEF
                     ILGSDGAGIIEAVGEGVDNLAVQTEVVILPTLNWEVTDDVPPVPDILGGPSNGTLAEYV
                     IIPSQNAVKKPSYLSWEEAGVLPLSALTAYRALFTKAQLKKGEHILIPGIGSGVATYAL
                     VMAKAIGATVSVTSRSEEKRKRAIQLGADHAFDSYSNWSEHLQGQKADVILDSIGPALF
                     SEYFDHVKPNGRIVSFGASSGDNLSFPLRSLFFPQINILGTSMGSRDEFHEMLHFMEKH
                     KLRPVLDRTYPIEQAHEAYTRMQEGSQFGNI"
     misc_feature    10223..10238
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.73"
                     /tool="antismash"
     gene            10315..11184
                     /locus_tag="C6372_RS06240"
                     /old_locus_tag="C6372_06235"
     CDS             10315..11184
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015239982.1"
                     /locus_tag="C6372_RS06240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06235"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_059352524.1"
                     /transl_table=11
                     /translation="MESGELKIFRAVAREGSITKAARQLNYVQSNVTARIHKLETDLNI
                     KLFHRTNRGMKLTAAGQNLLQYADQVLSLLDEAEKSAQLSQHPKGPLRLGALETTAVTH
                     LPEHAASFLRRFPEVDLSVNTGDTHSLVQQVLDHKVDGAFVYGPVEYMDIKQIPVSHEE
                     LVLISPEEGAIEDMLRLPMLFFGTGCSHRDRVKRLFEEAGIQQQKIIEFGTLEAVIRGV
                     SAGLGTALLPKSAIACSVHRQRVYVHQLPASYQDMTIVFIYRKDFFMTSAFQRFIAELN
                     ETKFIPSG"
     gene            complement(11475..13238)
                     /gene="ggt"
                     /locus_tag="C6372_RS06245"
                     /old_locus_tag="C6372_06240"
     CDS             complement(11475..13238)
                     /EC_number="2.3.2.2"
                     /GO_function="GO:0036374 - glutathione hydrolase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006751 - glutathione catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ggt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1274: gamma-glutamyltranspeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389723.1"
                     /locus_tag="C6372_RS06245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06240"
                     /product="gamma-glutamyltransferase"
                     /protein_id="WP_106294198.1"
                     /transl_table=11
                     /translation="MKKTWNVCLAALLSVLLVAGSAPFHAEAKKPPKGYDEYKQVDVGK
                     DGMVATAHPLASEIGADVLKKGGNAIDAAVAIQFALNVTEPMMSGIGGGGFMMVYDGKT
                     RDTTIIDSRERAPAGATPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEKALDKWGT
                     RSMKQLISPSIKLADKGFPIDSVLADAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLIQ
                     KDLAKTFKLIRSKGIDAFYEGRFAKALSDTVQDFGGSMTEKDLENYDITIDEPIWGEYQ
                     GYQIATTPPPSSGGVFLLQMLNILDDFNLSQYDIRSWEKYHLLAETMHLSYADRAAYAG
                     DPEFVNVPLKGLLHPDYIKERQQLISLDEVNKKPKAGDPWKYEEGTANYKQVEQPNDKV
                     DGQTTHFTVADRWGNVVSYTTTIEQLFGTGIMVPDYGVILNNELTDFDAVPGGANEVQP
                     NKRPLSSMTPTILFKDDKPVLTVGSPGGATIISSVLQTILYNIEYGMELKAAVEEPRIY
                     TNSMSSYRYEDGVPEDVLSKLKDMGHKFSTSPVDIGNVQSIFIDRENGTFKGVADSSRN
                     GAAIGINLRHK"
     misc_feature    13223..13238
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.81"
                     /tool="antismash"
     gene            13419..13649
                     /locus_tag="C6372_RS06250"
                     /old_locus_tag="C6372_06245"
     CDS             13419..13649
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389722.1"
                     /locus_tag="C6372_RS06250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06245"
                     /product="excisionase family DNA-binding protein"
                     /protein_id="WP_024121629.1"
                     /transl_table=11
                     /translation="MYLTIKETAEYANLSEDYIKSLVLEGKIRAVHDGEQFLIYKGQFK
                     THLEQLENYKALVQEILNEPIPEDIDVKDED"
     gene            13965..14510
                     /locus_tag="C6372_RS06255"
                     /old_locus_tag="C6372_06250"
     CDS             13965..14510
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389721.2"
                     /locus_tag="C6372_RS06255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06250"
                     /product="site-specific integrase"
                     /protein_id="WP_044155674.1"
                     /transl_table=11
                     /translation="MHIVQPIRSLEKIQDVKQYLRSKNKRDYFLFIFGINSALRISDIL
                     PLQVKDVRNKDHLWATESKTKKKRKILILESLKAEIYEYTKDMKENEYLFKSVRTRKPI
                     SRIQAYRILREAAEACGLEEIGTHTLRKTFGYHFYQRTKDIAELQRILNHSSPSITMRY
                     IGIDEDTTRAAYKVFGGL"
     tRNA            14565..14637
                     /anticodon=(pos:1117157..1117159,aa:Arg,seq:cct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="C6372_RS06260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="C6372_06255"
                     /product="tRNA-Arg"
     gene            14565..14637
                     /locus_tag="C6372_RS06260"
                     /old_locus_tag="C6372_06255"
     gene            complement(14726..15271)
                     /locus_tag="C6372_RS06265"
                     /old_locus_tag="C6372_06260"
     CDS             complement(14726..15271)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389720.2"
                     /locus_tag="C6372_RS06265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06260"
                     /product="IseA DL-endopeptidase inhibitor family protein"
                     /protein_id="WP_106294200.1"
                     /transl_table=11
                     /translation="MKKYLLFLTTIALILSLNTNVFAKNTSGDLSQKQALQLALTAREH
                     FWNTMSGHNPKAKKAVCPSGTFEHQNLQYVYMCSDLGTKEKAVNYLTPIFSKTAIEKGF
                     KDYHFVVSKGKLAVPVGDGDNLLNWKKSTAKLISKKGGTVTYEFTVPTLDGSPSAKRKV
                     TFVKENKKWKVNRFDAVI"
     misc_feature    complement(15487..15503)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.37"
                     /tool="antismash"
     gene            15560..16951
                     /locus_tag="C6372_RS06270"
                     /old_locus_tag="C6372_06265"
     CDS             15560..16951
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389719.2"
                     /locus_tag="C6372_RS06270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06265"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_106294202.1"
                     /transl_table=11
                     /translation="METLQENPVSKKKSNPSVWRSMSLFLVPLLLSNVLQSVGQLVGMV
                     AVGRWLGVDALAAVSSFFPLFFLLISFTIGIGSGSSILIGQAYGAKNEERLKAVVGTTL
                     TFTFLLGIVLAVIGSIFTLDILRLMGTPENVIHVSVSYARILFCAMPFMFLYFAYTTFL
                     RGTGDSKTPFYTLIVSTVINIALLPILILGMFGLPKLGIYGSAYATVISTIVTFIVLLV
                     YLRKTKHPLQFDKTVRRYLKMDKELLALLLRLGIPSSINMILVSLSEIAVISFVNHYGS
                     DATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANEFDRLKQVIRVGIWLNYIIGG
                     VLILLIYLFAHKILALFLTEKDTLYIAHRLLMITLWSYLLFGNAQIISATMRASGTVLW
                     PTLISIFAIWGIEVPVAFVLSHYTNLEILGIWVGYPAAFAVSLLLIYGYYQFIWKKKQI
                     TRLIQ"
     gene            17091..18065
                     /gene="galM"
                     /locus_tag="C6372_RS06275"
                     /old_locus_tag="C6372_06270"
     CDS             17091..18065
                     /EC_number="5.1.3.3"
                     /codon_start=1
                     /gene="galM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389718.1"
                     /locus_tag="C6372_RS06275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06270"
                     /product="aldose 1-epimerase"
                     /protein_id="WP_106294204.1"
                     /transl_table=11
                     /translation="MTNYIEKMTYLGTPAVKAGNEHLEIIVVPEWGSNVISLVDKETKM
                     HLLREPETTESFHDTPTLYGIPILFPPNRISDGTFTFRGRTYHFDINEKDKHHHLHGFL
                     YDKKWDIITMKQTDKEVIIETEIDLSKIPHVYKQFPHHAVVRMTYILKDNTLYKHATIM
                     NKGKDAFPWGLGYHTTFVFPEESSLFSLTADQQWELDERLLPTGKLIDIPNQEALHEGM
                     LLRQQLDDVFLSSYQKRGGENQAVIYHQHAHLNMIYKADEQFKHWVVYNADGTQRYLCP
                     EPYTWVTNAVNLELPSSLTGLQVLEPGEEKTVKSSITIKRNHR"
     gene            18092..19567
                     /gene="dacB"
                     /locus_tag="C6372_RS06280"
                     /old_locus_tag="C6372_06275"
     CDS             18092..19567
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0004175 - endopeptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="dacB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389717.1"
                     /locus_tag="C6372_RS06280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06275"
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="WP_106294206.1"
                     /transl_table=11
                     /translation="MRKSMKLYFVILLLFIFASIPYMHHAAHAAEEQDTLAGQIETILA
                     NEPALKGAMAGITVRSAETGDVIYDHLGDVRMRPASSLKLFTAAAALSVLGEDFSFTTE
                     VRTDGRLKGQKLNGNLYLKGKGDPTLLPADFDQMAEKLKKSGIKSIKGNLVADDSWYDH
                     IRYSPDLPWSDEYTYYGAQISALTASPNEDYDAGTVIVEASPGKKEGQKPAISVSPKTD
                     YVAIENEAKTVEAGKKKDLSIEREHGTNTITIKGSIPVDASKTKEWISVWEPAGYALDL
                     FKQALKKQGITVKGKIIMGTAPDSSDILASHHSMPLSKLFLPFMKLSNNGHAEVLVKEM
                     GKAEKGEGSWEKGLEVLNSTLPNFSVDPKTLILRDGSGVSHINAVSSDQITKLLYDIQD
                     EKWFQPYLHALPEAGNSDRLVGGTLRNRMKDTPAEGKIRAKTGSLSTVSSLSGYAETKS
                     GKTLVFSILLNGLIDDSDGKDIEDQIAVILANQ"
     misc_feature    complement(19856..19869)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.06"
                     /tool="antismash"
     gene            20001..>21681
                     /locus_tag="C6372_RS06285"
                     /old_locus_tag="C6372_06280"
     CDS             20001..>21681
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_Starter (3-302). E-value:
                     1e-87. Score: 286.2. Matches aSDomain:
                     nrpspksdomains_C6372_RS06285_Condensation_Starter.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389716.2"
                     /locus_tag="C6372_RS06285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6372_06280"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_142396279.1"
                     /sec_met_domain="Condensation (E-value: 1.8e-67, bitscore:
                     223.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.9e-23, bitscore:
                     77.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKENTYGLTHAQRRVWFTELLEPGTSICNLTACVKFRGDVDLDAL
                     QLALNLSISRNDAIRFQLTEGIESESEPRLYLAEYKGLSLEIIDFTNSEMTETEQWIHD
                     QARIPFKLLDSPLYQFYLLRIHPHEIWLYAKFHHIIMDGISLNLLGNQIIDLYQKIKKG
                     EPVPDEQEPSYISYIEKERQYLQSSRFEKDHLFWTQTYQQPPVYHSLTGQSTSQKQSTS
                     ASRDTITLSPYLAHTIQAFCEEQKISMISLFMASFYICISRITSKTDLAIGTYYGNRGS
                     KAEKEMLGMFVSSLPIRKTVDSDADFLSFARSVGREQLSVMRHQRFPYNLLVNELRKEH
                     KDLHNLIGISMQYHPLQWQKADDLNYETALYFSGYTANELSVQIQERIDTGAIQLNFDY
                     QNILFSLEDIKRIQHHLLTLLENALQNPHSTIKELDMAEKSEKGKVLYEFNRTKAISPS
                     ASTLHGLFERQAALTPDRTALRFSGGSLTYSQLDMYANRLAARLTAHGVTKESIVGVLS
                     ERSPDMLTAVLAVLKAGGAYVPLDPVYPEERLSYMLKDSGAAL"
     aSDomain        20010..20906
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6372_RS06285_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.00E-87"
                     /label="C6372_RS06285_Condensation_Starter.1"
                     /locus_tag="C6372_RS06285"
                     /protein_end="302"
                     /protein_start="3"
                     /score="286.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="NTYGLTHAQRRVWFTELLEPGTSICNLTACVKFRGDVDLDALQLA
                     LNLSISRNDAIRFQLTEGIESESEPRLYLAEYKGLSLEIIDFTNSEMTETEQWIHDQAR
                     IPFKLLDSPLYQFYLLRIHPHEIWLYAKFHHIIMDGISLNLLGNQIIDLYQKIKKGEPV
                     PDEQEPSYISYIEKERQYLQSSRFEKDHLFWTQTYQQPPVYHSLTGQSTSQKQSTSASR
                     DTITLSPYLAHTIQAFCEEQKISMISLFMASFYICISRITSKTDLAIGTYYGNRGSKAE
                     KEMLGMFVSSLPIRKTVD"
     CDS_motif       20019..20054
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS06285_0001"
                     /evalue="4.60E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="C6372_RS06285"
                     /protein_end="18"
                     /protein_start="6"
                     /score="9.9"
                     /tool="antismash"
                     /translation="GLTHAQRRVWFT"
     CDS_motif       20079..20195
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS06285_0002"
                     /evalue="1.20E-10"
                     /label="C2_starter_024-063"
                     /locus_tag="C6372_RS06285"
                     /protein_end="65"
                     /protein_start="26"
                     /score="34.0"
                     /tool="antismash"
                     /translation="ICNLTACVKFRGDVDLDALQLALNLSISRNDAIRFQLTE"
     CDS_motif       20406..20471
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS06285_0003"
                     /evalue="1.60E-08"
                     /label="C3_starter_134-155"
                     /locus_tag="C6372_RS06285"
                     /protein_end="157"
                     /protein_start="135"
                     /score="27.3"
                     /tool="antismash"
                     /translation="FHHIIMDGISLNLLGNQIIDLY"
     CDS_motif       20805..20894
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS06285_0004"
                     /evalue="6.70E-09"
                     /label="C5_starter_265-294"
                     /locus_tag="C6372_RS06285"
                     /protein_end="298"
                     /protein_start="268"
                     /score="28.2"
                     /tool="antismash"
                     /translation="DLAIGTYYGNRGSKAEKEMLGMFVSSLPIR"
     CDS_motif       20946..21059
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS06285_0005"
                     /evalue="9.60E-10"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="C6372_RS06285"
                     /protein_end="353"
                     /protein_start="315"
                     /score="31.0"
                     /tool="antismash"
                     /translation="REQLSVMRHQRFPYNLLVNELRKEHKDLHNLIGISMQY"
     CDS_motif       21582..21623
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6372_RS06285_0006"
                     /evalue="9.50E-07"
                     /label="NRPS-A_a2"
                     /locus_tag="C6372_RS06285"
                     /protein_end="541"
                     /protein_start="527"
                     /score="21.7"
                     /tool="antismash"
                     /translation="LAVLKAGGAYVPLD"
ORIGIN
        1 tttgatcaaa ataaagtagc ttttatcgga gccggatcta tggcggaagg aatgatatca
       61 ggtatcgttc gtgccaataa aatcccaaaa caaaacatct gcgttacaaa ccgcagcaat
      121 acagagcgat tagctgagct tgaacttcaa tatggaatca aaggcgtggc gccggatcac
      181 ttatgtattg aagacatgga tgtgctcatt ttggcgatga agccaaaaga tgccgaaagc
      241 gctctgtcat cattaaaaac acgcatccaa ccccatcaat taattttgtc ggtgctagcc
      301 ggcataacca cctcttatat tgaacaatca ttgcataatc aacagccggt tgtcagagta
      361 atgcctaaca catcaagtat gatcggcgct tctgcaactg ccatcgcact tggcaggcat
      421 gtgacagatg atttagaaaa actgacggcg gctttgctcg gctgcatggg tgaagtgtat
      481 acaatccagg aaaatcaaat ggacattttc acgggaattg ccggcagcgg ccctgcgtat
      541 ttttattatt taatggaatt catcgaaaag acaggcgagg aagcgggcct tgataaacat
      601 ttatcacgaa gcatcggtgc acagacactc ttgggtgctg caaaaatgct gatggagaca
      661 ggagaacagc ctgaggtgct gagagataat attacctcgc caaatggaac gactgctgcc
      721 ggattacagg ccttgaagaa gagcggcgga ggagaagcca tctctcaagc cattaaacat
      781 gcggctaagc gttcaaagga aatcagcgat gatatcgaaa aaacagcggc accgctataa
      841 aacaggagtg ataaagtgac gtctgaaaca gaaatgaaaa gagttgtcgt gaagatcggc
      901 agcagttcat tgacaagtct tcatggggaa atcagcattc gcaaactgga agctttagtg
      961 gaccaggtcg ccaaactaaa agacgccgga tatgaagtca tcctggtttc ttccggcgca
     1021 gtagcagcag gatatcgcaa gctcggattt cttcagcgac cagaaaatcc gcctgaaaaa
     1081 caagcgtctg cttcaatcgg tcaagggttg ctgatggagg cttattcaaa gctgtttttg
     1141 gcgcacggtt atgtggcttc ccaaatttta attacaagaa gcgacttttc tgatgaatat
     1201 cgatatcaca atgttcggaa cacaatgaat gtactgctcg aacgcggtat tatcccgata
     1261 attaacgaaa atgacacagt gaccgtcaat cggcttaagt ttggcgataa tgatacactc
     1321 gcggccaaag tcgccggatt aatcgatgcg gatctgcttg tgattttatc ggatatcgac
     1381 ggtttatatg acggcaatcc gcgaaataat ccaaaagcga aaagggtgca gcgagtcagt
     1441 gaggttacac cggaaattga agcgtgtgca ggcgatacag acagcgaagt cggcaccgga
     1501 ggcatgcggt ccaaactgga tgcgtttaaa attgtgatgg catccggcat aaaaggattt
     1561 cttggccagg cagacgctgc agatatatta tatcaagctg ttcatggaga ggcggaaggc
     1621 acctattttg aagctgaggg aacgcttccg ttgaatcaaa aagagcagtg gatcgctttt
     1681 aattccggac cagaaggtga aattgtgtta tcagatgact gttccggcca aatagctgac
     1741 ggtcaatcgc atatataccc agatggtgta agggagatta aaggaaaatt taaaagcggc
     1801 gctgttgtcc gcctgactga ttctcatggt gaagacatcg gcctcgggat cgtcaattat
     1861 tcttcctcgc agcttgagac acccgaaaaa aataaaggca tgaaaaacaa agctgtgatt
     1921 gatccagaag catttgtatg ccatgtggat ttatctttgc ctgtatatta aatagaagaa
     1981 atacacggga acaaaaaacc cgaacttctc cagagaagct cgggttcttt tttattgata
     2041 ctgttccaat ttcgagaaaa actgtatgac aaactcataa aaatcctgcg ctgacggtgc
     2101 aagctctctg tttttcggct taataatccc gacagtccgt ttcacttgag gaaactcaat
     2161 tggaattttc acagtaaatc ggggtgtcgt ttccgcaaaa gtgctctccg gcagaagggt
     2221 gacacccata cctgcggaca ccaatccttt gatagcgtcc aaatcctcac cctctgtaga
     2281 gacaagaggg gcaaacccgg cttgtttgca agagtcaatc gccatttttc tgagcacaaa
     2341 gccttccgga aacaacacaa attgatcgtt gcgcaaatcg attaaatgga ccgttttttg
     2401 tttggcgagc ggatgattta aaggtacaag cgcgtaaatt ttttccgtga ataaaatatt
     2461 tcctgctatg tctgggaaat tcgtcggcac cgggcctaat aacgctaaat cgatatcgcg
     2521 gtttctgaca gcttcaatca gaaacttata agagccttgg cgcagcaaaa actctacgtg
     2581 cggatattcc tctttaaatg ccgaaacgac agtcggcaga agctgactgg cgaggcttgt
     2641 aggaaagccg atttttacgg ttccgcgatg cgggtcaagg tactcatcaa tttgttcttt
     2701 tgcataatcg atggctttca tcgctgtttt gacatgaatt aaaaattctt ttccaatcgg
     2761 agtgagtttg atatttctcc cttcacgctc aaataaagta acatttaatt cttcttcaag
     2821 gtttgcaatt tgtctgctga ttgctgattg ggccacatgc agataatcag cggcttctga
     2881 aacgtgttca cgttcagcaa cctccataaa ataacgcagt tggcgcagct ccatgtaagt
     2941 ctcacatcca tctatctcat tttgagattc ttttgatcta aattatatat tgtttatatc
     3001 gttttgaaaa cctacaataa tattagagtt gttagatttt atgaccggta ttatcggaaa
     3061 ctgatcgggg gagaggaatt atgacttaca atcaaatgcc aaaagctcaa ggtctctacc
     3121 gtcctgaatt tgaacatgat gcatgcggaa tcggcctata tgcgcactta agaggcaagg
     3181 cgacacatga catcgtcaaa caggggctgc agatgctttg ccagctcgac cacagaggag
     3241 gtcaaggcag tgatccggat acgggagacg gcgccggctt actggttcaa atccctgatg
     3301 ctttctttaa gaaagagtgc aaagacatca atctgccgga aaaaggacgt tacggggtag
     3361 gaatggtctt tttctcgcag aaggaagatg aaagaaaaaa aatcgaaaag caaatcaatg
     3421 cactgattga acaggaaggc caagttgtgc ttggatggag aactgtacct ataaatgtcg
     3481 gaaaaatcgg aacagtagca caaaaaagct gtccgtttgt ccgtcaagta ttcattggcg
     3541 caagttctga cctgaaggat gatttgtcct ttgagcgaaa attgtatgtc attcgtaaac
     3601 aggctgaaaa ctggggagta acggaaggtc tagattttta ttttgccagt ctttcaagcc
     3661 aaactatcgt ttataaaggc cttttaacac ctgaacaggt tgatgcgttt tattccgatc
     3721 tgcaagatga ggcattcgta tccgcttttg cactagttca ttcacgcttc agcactaata
     3781 ccttccctac atgggaaaga gcacacccaa accgttattt ggttcacaat ggtgagatta
     3841 acacccttcg aggaaatatc aactggatga gagcacgcga acagcaattt gtgtctgaaa
     3901 gttttggtga ggatctcaat aaaattcttc cgattctgaa tgctgacggc agtgactctt
     3961 ccattttaga taacgcattt gagtttttcg ttatggcggg acgcaagccg gcacatacgg
     4021 cgatgatgct gattcctgag ccatggacag aaaatacgca catgtctaaa gaaaaaagag
     4081 cgttttatga gtatcacagc tcattaatgg agccttggga cggtccgacg gccatttcat
     4141 ttactgacgg aaaacaaatc ggcgcaatac tcgaccgaaa tggtttacgt ccggcccgtt
     4201 attatgtgac aaaagatgat tatattattt tctcatctga ggtcggtgtt attgaggttg
     4261 aacaggaaaa cgttttatat aaaaaccgcc ttgaaccagg aaaaatgctt ttaattgacc
     4321 tggaagaagg ccgcattatt tctgatgaag aagtaaaaac acaaatcgca actgaatatc
     4381 cgtaccaaaa atggcttgag gaagagcttg tgcaagtgaa tcctgatccg gaaacaagag
     4441 aggaagagca gttcacggat cttcttacgc gtcagaaagc gtttggatac acatatgagg
     4501 atattcaaaa atatttaatt cctgttatta aagaaggaaa agatcctctc ggctcaatgg
     4561 ggaacgattc gccgcttgct gttttgtctg atcgcccgca atcgctgttt aactacttta
     4621 agcaattgtt tgcacaggtt accaacccgc cgattgacgc gattcgcgag cagctcgtga
     4681 cttcaacaat gacttggctc ggagcagaag gcgatctcct tcatccgaat gaacggaacg
     4741 tccgccgaat caagctgtat acacccgtgt tatccaatga gcagttttat gcgctgaaaa
     4801 ccatcgtcca tcctgattta agaagccaaa aaatgaatgt gctgttttca gaagatcttg
     4861 aacgcgggtt aaaagacatg ttcacccaag ctgagaaagc aatcagccaa ggcgtcagtc
     4921 ttttgatttt gtccgataga gcaatgaatg agcagttaac gccaattccg ccgctgttag
     4981 cagtcagcgc actgcaccag catttaatcc gaaaaggatt gcgcacgaaa gtcagcatta
     5041 tcgttgaatc gggagaagca cgtgaggttc atcacttcgc agctctaatc ggctatggag
     5101 ccgacgctgt caatccttat ctggcatatg cgacctacaa gcaggaaatt gatgaaggcc
     5161 gtttggatat cagctatgaa gaagcggtca gcaagtatgg aaaaagcatt accgaaggtg
     5221 tcgtaaaagt gatgtcgaag atggggattt ctactgtaca gagctacagg ggcgcccaaa
     5281 tctttgaagc ggtaggaatc agccgtgacg tgattgaccg ttattttacg ggaacagcat
     5341 cacagctcgg cggcattgac ttaaatacca ttgccgaaga ggcgcagcgc cgccaccagg
     5401 aagcgtataa agatgactac agcaaaacgc ttgaaccggg aagtgacttc caatggagaa
     5461 acggcggaga gcatcacgca tttaacccga aaacgattca caccttgcaa tgggcgtgcc
     5521 gcagaaatga ttacaatctg tttaaacaat atacgaaagc ggcagatgaa gaacgaatcg
     5581 gatttctgcg aaacttgttc tcatttgatg agaaccgcaa gcctctaaaa gtggaggaag
     5641 tagaatctgc tgaatcgatt gtcaaacgtt ttaaaacagg tgcgatgtca tttggatcat
     5701 taagcaaaga agcccacgaa gcattagcga ttgcgatgaa ccgcctgggc ggaaaaagca
     5761 acagcggtga aggcggagaa gatccaaaac gctttgtgcc tgatgaaaac ggcgatgaca
     5821 gaagaagcgc gatcaaacaa attgcatccg gacgattcgg tgtaaagagc cattacttag
     5881 tcaatgccga tgagctgcag attaaaatgg cgcaaggcgc aaaaccggga gaaggcggac
     5941 agctgccagg caataaagtg tatccttggg ttgccgatgt ccgcggatca acacctgggg
     6001 tcggattgat ttcaccgcct ccgcaccatg acatttattc aatcgaggat ttagcccagc
     6061 tgattcacga tttaaaaaat gcgaaccgtg atgcaagaat cagcgtgaag ctggtctcaa
     6121 aagctggtgt cggaacgatc gctgcgggtg ttgctaaagc aactgcagat gtcatcgtta
     6181 tcagcggtta cgacggaggt acaggtgctt cacctaaaac aagcattaaa catacagggc
     6241 ttccgtggga gcttggcctt gcagaagcgc accaaacctt aatgctgaac ggactccgtg
     6301 atcgtgttgt attagaaaca gacggaaagc ttatgacagg ccgggacgtc gtcatggccg
     6361 cattgctcgg cgctgaagaa ttcggtttcg caactgctcc gttagttgtt ctcggctgtg
     6421 ttatgatgcg cgcctgccat ttggatacat gtcctgtcgg ggtagcgact caaaatcctg
     6481 aacttcgcaa aaagttcatg ggagatcctg atcatattgt gaactacatg ttgtttattg
     6541 ctgaagaagt ccgtgaatac atggctgcat taggttttaa aactttcgat gaaatgatcg
     6601 gccgcactga cgcacttaac gtgagtgagc gggcaaaggc gcattggaaa gcgagccagc
     6661 ttgatttgtc cacacttctt tatcagccgg aaggcgtacg gacattccaa acgccgcaaa
     6721 accataaaat tgatcaatcg ctcgatatca caacgattct tcctgctgta aaagatgcca
     6781 tcgaatcggg aaaagaagct ggtatttcag tcgaaatcaa taacacaaac cgtgtagcag
     6841 gtactgtaac aggcagtgaa atttcgaaac gttacggcga agaaggactt ccggaagata
     6901 cgattaagct gcaattcaca ggatcagccg gccaaagctt tggagcgttc gttccaaaag
     6961 gcatgacgct ttatttagac ggagattcaa atgactacgt cggaaaaggt ctgtctggcg
     7021 gaaaaatcat tgtcaaatca ccggaaggat tcaactccga atcacatgat aatgtaatta
     7081 tcggcaacgt agcattctat ggcgcgacga gcggagaagc atatattaac ggccgtgcag
     7141 gtgaacgctt tgccgttcgg aacagcggtg tgaatgttgt tgttgaaggc atcggtgatc
     7201 acggctgtga atacatgaca ggcggaagtg ttgtcgtact gggtgatgtc ggcaaaaact
     7261 tcgcggctgg tatgtccggc ggaatcgcgt atgtattggc cgaagatgta aaagcattta
     7321 aacgcaaatg caaccttgaa atgattttgt ttgagtcatt agaagatgaa aaagaaattc
     7381 agcaagttaa agcaatgctt gaaaagcatg ctgcatatac aaacagccaa aaagcagcag
     7441 acctgcttga acagtgggaa gacagcgtga aaacattcat taaagtgatt ccgaaaaact
     7501 ataaacaaat gcttgcgagc atcgaagagc aaaaagctgc tggcttatct gaggaagaag
     7561 ccgtcatgta cgcgtttgaa gccaatacga aaccaaagca gaaaaaagcg ccggcgggac
     7621 aaaaacaagc ggtagtacag taaggaaggg gagaggaaca tggggaaacc aactggattt
     7681 atggaaatca aacgagaaaa accagctgag cgagaccctc tcactcgctt aaaggactgg
     7741 aaggaatatt ctgctccttt ttcagaagaa gcgtcgaaac ggcagggggc gcggtgtatg
     7801 gattgcggta caccgttttg ccagatcggt gccgacatta acggatttac atccggctgt
     7861 ccgatttaca acttaattcc tgaatggaac gatcttgtct accgaggcag atggaaagaa
     7921 gcattagaac ggcttgtaaa aacaaacaac tttcctgaat tcacagggcg ggtttgtccc
     7981 gctccttgtg aagggtcatg tacactagcg atttccgacc cggccgtatc gattaagaat
     8041 attgaacgga ccattattga taaagggttt gagaatggct ggattcagcc taggattccg
     8101 aaaaaacgta caggcaaaaa agttgccatc gttgggtcgg gcccagccgg actggcgagt
     8161 gctgaccagc tgaaccaagc tggacattct gtcactgtat ttgaacgcgc agacagagcg
     8221 ggcggacttt taacttacgg cattccaaac atgaaacttg aaaaaggaat tgtcgaacgc
     8281 cgtattaagt tgctgacgca agaaggaatc gattttgtta caaatacgga aattggcgtt
     8341 gatataacgg ccgatgagct gaaagagcaa tttgattccg taatcctttg cacaggtgct
     8401 caaaaacagc gggatctatt aatcgagggg cgcgaatcaa aaggtgttca ctacgcgatg
     8461 gattacttga cgcttgctac aaaaagctat ttagattcta actttaaaga caagcgattc
     8521 attgatgcga aggggaaaga tgttatcgtg atcggaggcg gagacacagg ggctgactgt
     8581 gtggctaccg ctttgcgcca aaaagccaaa agcgtgcacc aattcggcaa acacccgaaa
     8641 cttcctccgg ctcgcacgaa tgataatatg tggcctgaac agccgcacgt ctttacgctt
     8701 gaatatgcat atgaagaagc agaagcaaaa ttcggaagag atccgagaga atattcgatc
     8761 caaacaaaaa aattgattgc cgataaaaac ggcaaattga aagagctcca tacgattcaa
     8821 atggagaaag tgaaaaatga gcatggaaaa tacgagttcc gtgaactgcc tggaactgaa
     8881 aaagtatggc ctgctcagct cgtctttatc gctatcggct ttgaaggcac agaacagccg
     8941 cttttaaaac aatttggtgt tgattctaat aacaacaaaa tcagcgcagc atatggggat
     9001 tataaaacaa atatcgatgg tgttttcgcc gcaggggatg caagaagagg ccaaagttta
     9061 atcgtatggg cgattaatga aggccgtgaa gtggcgcgtg aagttgaccg atatttgatg
     9121 gggagttcag ttctgccgta aataaagggg attatataaa aaaagaaacc ggactgtttg
     9181 tcagccggtt tcttttttaa tctattgtga tcccgatgtt cccaaactgg ctgccttcct
     9241 gcattctggt atatgcttca tgtgcttgtt ctataggata tgtccggtca agcacgggcc
     9301 gaagtttatg tttttccatg aaatgcagca tttcatggaa ttcatcacgg cttcccatcg
     9361 acgttcccaa tatattgatt tgcggaaaga ataaagaacg cagcggaaaa ctgagattat
     9421 cacccgaact tgcaccaaag ctgacaatac ggccattcgg tttaacatga tcaaagtatt
     9481 ctgaaaagag ggccggtcct atgctatcga gaatgacatc agctttttgt ccttgaagat
     9541 gttcagacca attgctgtaa ctgtcaaaag cgtggtcagc acctaattgt attgctcttt
     9601 ttcttttttc ctcgcttcga gaagttacgc ttacagttgc tccaatcgct ttagccatta
     9661 ctagcgcgta ggttgcaacg ccgcttccaa ttccgggtat caaaatatgc tcgccttttt
     9721 ttaattgggc ctttgtaaaa agtgctcgat atgcggtcag agctgataat ggcaacacgc
     9781 ctgcttcctc ccaggataga taagaaggtt tttttactgc gttttgtgaa ggaatgatca
     9841 catattcagc aagtgttccg tttgaagggc ctcccaaaat atccggaaca ggaggtacat
     9901 catctgttac ttcccaattc aaagtcggta aaatcaccac ttctgtttga acagccagat
     9961 tatctacacc ttcaccgacc gcttcaataa taccagcacc gtcagagccc agaataaact
    10021 cagaatcttg ttcagtttta tttttcatga gaaacaggtc ccggtgattt aatcccgccg
    10081 ttttcaactt tactttcact tctccgtatc cgggattttg agaagggagg tcctgatacg
    10141 ctaacccccg aagtccgctt tttccgttat gaataaccgc tttcatgccg tctgcctcct
    10201 atattccttg taatctatga tcttcacata ttttacacag cggttttctt caagtaaaat
    10261 gaacaaaaat gattgccggt atcactttta atcatagcaa gaaggtgaca gcgtgtggaa
    10321 agcggagaat taaagatatt ccgggctgtt gcccgtgaag gaagtataac aaaagcagcc
    10381 cggcagctga attatgttca atctaatgta acagccagaa tccataagct tgagacagat
    10441 ctgaatatca agttatttca ccggacaaat cgtggaatga agttaacggc tgcagggcaa
    10501 aacctattac aatacgcaga tcaagtttta tcattattag acgaagctga gaaatcagcg
    10561 cagttaagtc agcatccgaa agggccgttg cggcttggag cattggaaac aacagcggtc
    10621 actcacctgc ctgaacatgc agcttcattc cttagacgtt ttcctgaagt tgatttatca
    10681 gtgaacacag gtgatacgca cagcttggtt cagcaagttc tagatcataa ggtggatggc
    10741 gcttttgtct acggtcctgt tgaatacatg gatatcaaac aaattcctgt ttcccatgag
    10801 gaattggtgt tgatttcacc ggaggaaggg gcgatagagg acatgcttcg gctgccgatg
    10861 ctcttttttg gaaccggctg ctctcatcgc gatagggtca aaagattatt tgaggaagcc
    10921 ggtattcaac agcaaaaaat catagaattt ggcacattgg aagccgttat cagaggagtt
    10981 tccgctggtt tgggaacggc gctgctgcca aagtcggcca ttgcctgctc tgtccatcgc
    11041 caaagggtgt acgttcacca gcttcccgca tcatatcagg atatgacgat cgtgtttatt
    11101 tacagaaaag acttttttat gaccagtgca tttcagcggt ttattgcaga attgaacgaa
    11161 accaaattta tcccatcagg ctaatcaaga agagaagatt caacaatagc agggatacgg
    11221 gatagatttt tgttttcgta agctggagag actgttttca aaaaaacaaa gaagctttaa
    11281 ggtctatgaa ttgattagct gatcaaacct ttatgtgttt cgaattgtta tctggcacat
    11341 gtctggatgt tatattgaaa ggtattcgta ccgacattag attcgcgtta aggagtatgc
    11401 gaggaccata ggcaagatta atcgttcaca gcaaaaaaac tgtactcggc aaaaatgagt
    11461 acagtttttc ttttttattt atgtcttaaa ttaattccga tcgctgcgcc gtttctgctt
    11521 gaatcggcta ctcctttgaa ggtgccgttt tcacggtcga taaaaatgct ttgcacgttt
    11581 ccgatgtcca ctggacttgt gctgaattta tggcccatgt cttttaattt gctgagtaca
    11641 tcctctggaa ctccgtcttc gtatctgtag gagctcatac tgtttgtgta aattctcggc
    11701 tcttcaaccg ctgcttttaa ctccattcca tattctatat tatagaggat ggtttgcagc
    11761 acggaagaaa taatcgttgc ccctccagga gatccgacgg tgagaactgg tttgtcatct
    11821 ttaaacaaaa tcgtcggcgt catgctgctt aatggccgct tgttcggctg aacttcgttg
    11881 gctccgcctg gaaccgcatc aaaatctgtt agttcattgt ttaaaatgac gccgtaatca
    11941 ggaaccataa tacctgttcc aaacagctgt tcaattgttg ttgtatagga aacaacattg
    12001 ccccagcggt ccgcgacggt aaagtgtgtc gtttggccgt ctactttatc attcggctgt
    12061 tcgacttgct tatagtttgc ggttccttct tcgtatttcc aaggatcacc ggcttttggt
    12121 tttttgttga cttcatctaa actgattaat tgctggcgct cttttatata gtcggggtga
    12181 agcaaacctt tgagaggaac atttacaaat tcgggatcgc ctgcataagc cgcgcggtca
    12241 gcgtaagaca aatgcatggt ttcagcgagc agatggtatt tttcccatga gcggatatca
    12301 tattgtgaaa ggttaaaatc atcgagaatg ttcagcattt gcagcaaaaa cacgccgcca
    12361 gagcttggag gaggagtcgt tgcgatttga tagccctgat attctcccca aatcggttcg
    12421 tcaattgtaa tgtcgtaatt ttctaaatct ttttcggtca ttgatccccc aaaatcctga
    12481 acagtatcag aaagggcttt ggcaaatctg ccttcgtaaa aggcgtctat gcctttcgaa
    12541 cgaatgagct taaaggtttt ggccagatct ttttgaatga gcgtatcgcc ttctttaagc
    12601 ggctcgccat tcggcagaaa tacatcctta gcggcagttc gtgataattt ttcctgataa
    12661 tcagaaatcg catctgctaa cactgaatca atcggaaagc ctttatcagc gagtttaata
    12721 gagggggaaa ttaattgttt catcgaacgg gttccccatt tatccaaggc tttttccagc
    12781 cctttcagtg tacccggaac accaacagca gtaccttttg tgacacgttc ggagaagggt
    12841 atcgctttgc cgttttcatc gagaaacata tccggagttg cgcctgcggg agcgcgttca
    12901 cggctgtcaa tgatcgtcgt atctcttgtt tttccgtcat acaccatcat aaaaccgccg
    12961 ccgccaatac ctgacatcat cggttctgtg acattaagcg caaactgaat ggcaaccgcc
    13021 gcgtcaatgg catttccgcc ttttttcagg acgtcagctc cgatctctga agcaagagga
    13081 tgcgcagttg caaccattcc gtctttgcct acatctactt gtttgtactc gtcatagcct
    13141 ttgggcggct ttttagcttc cgcgtgaaat ggagcacttc cagcgactaa cagaacacta
    13201 agcagggctg ctaaacagac gttccacgtt tttttcatgt tctccctcct attaagctgt
    13261 tatgttacaa tcttagcgta aaaaaaatac agcggtttca caagtgacaa atggtatata
    13321 atctatatca tccggcctta tttctgtgtg aaattgatta tattggggta agtcatgcta
    13381 tagtagaaac agcatacgga ttaagaaagg aatgctatat gtatttaacg attaaagaaa
    13441 cagcagaata tgcaaatctt tcagaggatt atattaaaag tttggtgctc gaaggaaaaa
    13501 tcagggccgt tcatgacggt gagcaatttt tgatttataa gggacagttc aaaacgcatc
    13561 tcgaacagct ggaaaattac aaagcgctcg tgcaggaaat attaaatgaa ccaatccccg
    13621 aagatattga tgtaaaggat gaggattagg acacaatttg aaattgtgtc tttttttgca
    13681 tctttttttg agagcatctc gaaaagcaaa gcgtcatatt gcgttttaag ggctttttcg
    13741 ggaagggtta gagtgatttg tctcaggagt cgaaaaagct ttatatgagc ctgtaaatgt
    13801 catttcagaa gatagggcgt ttcaagaaat cttttttctg cttatgtaac actatgtata
    13861 ttatgttaca taaatgcctc cgaactttga cattcaacgt ttttccgcta taatagtaac
    13921 atagacctca aaacgttaca taacggtttt taaggagttt tttgatgcat attgtacagc
    13981 cgatccgcag tttagagaaa attcaagatg tgaaacagta tttacgcagc aaaaacaagc
    14041 gtgattattt tttatttatt ttcggcatta acagcgcgct ccgaatttct gatattttgc
    14101 cgcttcaagt gaaagatgtc agaaataaag accatttatg ggcgactgaa agcaaaacaa
    14161 aaaagaaaag gaagattctc attttagaat ctttgaaagc agaaatatac gagtatacga
    14221 aagacatgaa agaaaatgaa tatctcttta aatctgtccg aaccagaaag ccaatttcac
    14281 gcattcaggc atacagaatt ttaagagagg cagccgaagc gtgcggactt gaggaaatag
    14341 ggacccatac gctccggaaa acatttggct atcatttcta ccagcggaca aaagatatcg
    14401 ctgagctgca gaggattctt aatcattcat caccttcaat tacaatgcgt tatattggaa
    14461 tcgatgaaga tacaacaaga gctgcttata aggtatttgg agggctgtaa atcaaatcgc
    14521 ttgaaaatcg tgacaatcgg agctactata tagatattaa aaatgctcta gtagcacagc
    14581 ggatagtgca gcagtttcct aaactgcagg tcgggagttc gaatctctcc tagagcgtaa
    14641 taaaacaaaa gggcaatgga cgatacgtcc attgcctttt ttatgctgaa cataaaaaac
    14701 gcccgagaaa aacgggcgtt ttttcttata taactgcgtc aaagcgattt actttccact
    14761 ttttattctc ttttacaaat gtcactttcc gttttgctga aggtgatccg tccaaagtag
    14821 gaacggtaaa ttcatatgtg actgtgccgc cttttttaga aatgagttta gcggttgatt
    14881 ttttccaatt taagagattg tctccgtcac cgaccggaac agccagtttt ccttttgaga
    14941 caacgaaatg atagtcttta aagccttttt caatcgctgt ttttgagaaa ataggtgtta
    15001 agtaattcac agctttttct tttgtaccaa ggtcactgca catgtatacg tactgaaggt
    15061 tttgatgctc gaatgtgcct gatgggcaaa ctgctttttt cgcttttgga ttgtgtccgc
    15121 tcattgtatt ccaaaaatgc tctcttgctg ttagcgccag ctgcaatgct tgtttttgtg
    15181 ataaatcccc ggatgtgttt ttcgcaaata catttgtgtt caatgacaga ataagtgcaa
    15241 tagtggttag aaatagaaga tattttttca atgtggctct ctcctttaaa atctctttct
    15301 cttatgttac aaatgttaca atagttacgt ttagattaca atacttttgc ataaattatt
    15361 ttttattctt tcatctcacc aaaagactat gctgtatcgc actagtttat tctggcagat
    15421 tgaaaaatgt gtaaaaatag gagaatcggg aagggtttta taagtactgt ggtgaatagt
    15481 tacatgttgc atgtcgtgtt catttcaaaa gaaacgggag cacgttagtg aaacgagttt
    15541 aaataaagga gtcattcata tggaaacatt acaagaaaat cccgtatcta agaagaagag
    15601 caatccatct gtttggcggt caatgtcact atttttagtg ccgctccttc tgagcaatgt
    15661 gctgcaatca gtgggccaat tagtcgggat ggtcgctgtg ggcagatggc ttggcgtaga
    15721 tgcgcttgca gctgtctcat cctttttccc gctgtttttt cttctcattt catttacgat
    15781 cggcatcggt tccggcagtt ccattcttat cgggcaagcc tatggggcaa aaaatgagga
    15841 acggttaaag gccgttgtcg gaacaacgct gacattcacc tttttattag gaattgtgtt
    15901 agctgtgatc ggcagtatat tcaccttaga tattctgcgt ctcatgggca cgccggaaaa
    15961 tgtaattcat gtcagtgtca gctatgcacg tatcttattt tgcgcaatgc cgtttatgtt
    16021 tttatatttt gcttatacca cattcttgcg ggggacagga gattctaaga caccgtttta
    16081 tacattgatt gtaagcacag tcatcaatat cgcactttta ccgatcttaa ttctcggcat
    16141 gttcggtttg ccgaagctgg gcatttacgg ctctgcttac gcaacggtta tttctacaat
    16201 tgtgaccttt atcgtattat tggtgtatct gcggaaaacg aaacacccgc tgcaatttga
    16261 taagacagtg cggcgttatt tgaaaatgga taaggaactg ctggcgcttc tgctgcgtct
    16321 tggtattccg tcaagcatta acatgattct cgtctcacta tcggaaatag cggtcatttc
    16381 attcgtcaat cattatggct ctgatgcaac cgcagcatat ggcgtggtca atcaggtagc
    16441 cagctatgtg caaatgccgg ctgtcagtct ggggatcgcg gtgtctattt tcgccgctca
    16501 atctattgga gcgaatgagt ttgaccggtt aaagcaagtc attcgggtcg gtatttggct
    16561 gaattatatc attggcggtg tgctgatcct ccttatctat ctttttgcac ataagatttt
    16621 agcattattt ttgaccgaga aagataccct ttacattgca cacaggcttt tgatgattac
    16681 gttatggagc tatttgctgt ttgggaatgc ccaaattatt tctgcgacga tgcgtgcaag
    16741 cggaacggtt ttgtggccga ccctcatcag tattttcgcc atctggggaa tcgaagtgcc
    16801 ggtcgcgttt gttctgtctc actatacaaa tcttgaaata ctcggcattt gggtaggcta
    16861 tccggcagca tttgccgtga gtttactttt gatttacggg tattatcaat tcatttggaa
    16921 aaagaagcag attacacgtc tgattcaata aactccaaga gaacaccgtt cattttgaat
    16981 ggtgtttttt gtttacttaa agactaaagg gaaaacataa aatggaggaa atagtgcaca
    17041 ctgaattgaa tttatatata agcattgaac taaggagagg ttgagtacac atgacaaatt
    17101 atattgaaaa gatgacgtat ttaggaacac cagctgtcaa agcgggtaat gagcatttgg
    17161 aaataatagt cgtgcctgag tggggcagca acgtcatttc tctcgtagac aaagaaacaa
    17221 agatgcacct tttacgagaa ccggaaacaa ctgaaagctt tcatgacaca cctacattgt
    17281 atggaattcc cattttgttt ccgcctaatc gcataagtga cggaacgttc accttccggg
    17341 gcagaacgta tcattttgat atcaatgaaa aggataaaca ccatcacctt cacggctttc
    17401 tctatgacaa aaagtgggac atcataacaa tgaaacaaac agacaaagaa gtgatcatag
    17461 aaactgaaat tgatctttcg aagattcccc atgtttataa acaatttccg catcatgctg
    17521 ttgtacggat gacatacatt ttaaaagata acactcttta taagcatgcc acgatcatga
    17581 ataaagggaa ggatgcattt ccttgggggc ttggttatca tacgaccttc gttttcccgg
    17641 aagagagctc tttattttct cttactgctg atcagcaatg ggaattggat gagcgtttat
    17701 tgccgaccgg aaagctgatc gatataccga atcaggaagc tttgcatgaa ggaatgcttt
    17761 tgcggcagca gcttgatgat gtctttttat cttcttatca gaagagaggg ggagaaaatc
    17821 aggctgtcat ttaccatcag catgcacacc tgaatatgat ctacaaggcg gatgaacaat
    17881 ttaagcattg ggttgtgtat aatgcagatg gaacacaaag atatttgtgc ccggagcctt
    17941 atacatgggt gacaaacgca gttaaccttg agctcccttc gtcactcacc ggcttacaag
    18001 tgttagagcc tggtgaagag aagacagtaa aaagcagcat cacgattaag cgtaatcatc
    18061 gttagccatt caggagaggc gggataagaa aatgagaaaa agcatgaagc tttattttgt
    18121 aatattgctg cttttcatct ttgcttccat tccatatatg catcatgctg cacatgcggc
    18181 tgaagaacag gatacacttg ccgggcagat tgaaaccatt ttagccaatg aacctgcttt
    18241 aaaaggcgca atggccggca ttactgtccg ttctgcagaa acaggcgacg tcatatacga
    18301 ccatttaggg gatgtccgga tgagacccgc ctcttctttg aagcttttta cagccgccgc
    18361 ggcactttct gttctcggtg aggatttttc tttcacaaca gaagtgcgga cagacggccg
    18421 cctcaaagga caaaagctga atggcaacct ttatctgaaa ggaaaaggag atccgacact
    18481 tttaccagct gattttgatc aaatggccga aaagctgaaa aaatccggca tcaagtccat
    18541 aaaaggcaat cttgtcgccg atgactcatg gtatgatcat atccgctatt cgcctgattt
    18601 gccatggagt gatgagtaca cttattacgg cgcgcaaatt tccgcactaa cagcgtctcc
    18661 aaatgaggac tatgatgcag gcactgtgat agtagaagcc agtccgggaa agaaagaagg
    18721 acaaaagcca gcaatatcag tgtcaccaaa aacggattat gtagcgattg agaatgaggc
    18781 gaaaacagtt gaggcgggaa aaaagaaaga tctttctatc gaaagagaac atggaacaaa
    18841 cactattacg attaaaggga gcataccggt tgatgcgagc aaaacaaaag agtggatttc
    18901 cgtctgggag ccggcaggat atgctttaga tttatttaag caggctctta aaaaacaagg
    18961 cattacagta aaagggaaaa tcataatggg cacagcgccc gactcttcag acatactggc
    19021 ctctcatcac tcaatgcctt tgtctaagct atttcttcct tttatgaaat taagcaataa
    19081 cgggcacgcc gaggtacttg taaaagagat ggggaaagcg gaaaaaggag agggcagctg
    19141 ggaaaaaggg cttgaagtgc taaacagtac gcttccgaat ttcagcgttg atcccaaaac
    19201 acttattttg agggatggtt cgggggtctc tcatattaac gccgtatcat cagaccaaat
    19261 cacaaagctg ttatatgaca ttcaagatga aaagtggttt caaccttatc tgcatgctct
    19321 gccggaagcg gggaacagtg acagactggt aggcgggacg ctaagaaacc gcatgaaaga
    19381 caccccggca gaaggaaaga taagggcaaa gaccgggtcg ttaagcactg tcagctctct
    19441 gtctggctat gcagaaacaa agagcggaaa aacgctcgtt ttctctattc ttctaaacgg
    19501 tttgattgat gactcggatg gcaaagacat tgaggatcaa attgctgtta tcttggcaaa
    19561 tcaataaaaa cgctaaacct gttttcgtgg aaaacaggtt tttttatgtt tctttttaca
    19621 ttatcgcgct tgtttttaaa acattcagct aaatattgta gaaatgtaac ctgatactga
    19681 ggcggagaat atcttataaa cggtccaaca ctatcctcat atgaaattaa ataaacgaag
    19741 aaaaaatcta gtgatgaaga actattaaaa atcattactt tcataacttt acattcgaaa
    19801 tcctaataaa attaatcaag aaaaataaat aattaatact atattcaaaa aaatgttata
    19861 aaaattttat attttttatt gtactttaaa aaaattcggt taatataatg catatatgga
    19921 ttatatagtc atataatttc tttttattgt aattatttca gtttcttatc ctcttataaa
    19981 ttagaattgg agggaattcg ttgaaagaaa atacttatgg tttaactcat gcccaaagga
    20041 gagtttggtt tactgaactg ttggagcctg gtacaagcat ctgtaatctg accgcctgtg
    20101 taaaattcag gggtgatgtt gatcttgatg ctcttcagct ggctctgaac ctttcaatct
    20161 cccgtaatga tgcaatcagg ttccagctga cagaaggaat tgaatcggag tcagagcctc
    20221 gtctgtatct tgcagaatac aaaggattat cacttgaaat aatagatttt acaaattctg
    20281 aaatgacaga aacagagcaa tggattcatg atcaagccag aattccgttt aagctgcttg
    20341 attcgcctct gtatcaattt tatctcctta gaatccatcc tcatgagatt tggttatatg
    20401 cgaaattcca tcatattatc atggatggca tctctttaaa tttgctggga aatcaaatta
    20461 ttgatctgta tcaaaaaatc aaaaaagggg agcctgtacc cgatgagcaa gagccttcct
    20521 acattagcta catagaaaaa gagaggcagt acttacaatc ttcacgtttt gaaaaagacc
    20581 atttgttttg gacgcaaacc taccaacagc ctccggtata ccactcacta accggacaga
    20641 gcacttcaca aaagcagagt acctccgcat cgagagatac tatcacactt tcaccttacc
    20701 tagcccatac catccaagct ttttgcgaag aacagaaaat cagtatgatt tccttattta
    20761 tggcttcatt ttacatatgt atcagccgca tcacctctaa aacggacctt gcgatcggaa
    20821 cttactatgg aaacaggggg tcaaaggcgg agaaagaaat gcttggcatg tttgtcagtt
    20881 ctcttccaat tagaaaaacg gttgattctg acgccgattt tctttccttt gcacgcagtg
    20941 tcggcagaga acagctttca gtcatgcgcc accaaagatt tccttataat ttgctggtga
    21001 atgaattaag aaaagaacac aaggatttac acaacctgat cggtatatca atgcagtacc
    21061 atccgcttca gtggcaaaaa gcggatgatt tgaactatga gacggcgctt tatttcagcg
    21121 gatacaccgc gaacgagctt tctgttcaaa tacaggagcg gatagatact ggagccattc
    21181 aattaaattt cgactatcaa aatatcttat tttctcttga ggacattaaa cggattcagc
    21241 accacctgct tacgttgctg gaaaacgcgc ttcaaaatcc gcatagtact ataaaagaat
    21301 tagatatggc agaaaagtct gagaaaggaa aagttttgta tgagtttaac agaacgaaag
    21361 ctatttcccc ttcagcatcg acgttgcacg ggctgtttga acgtcaggcg gctttgacgc
    21421 cggatcggac ggctttgcgc ttttctggcg gctcgctgac ttactcgcag ctagacatgt
    21481 acgccaacag gctggcagcg cgccttacgg cgcatggtgt cacgaaggaa agcattgtcg
    21541 gtgttctaag cgaacgttcg ccggacatgc tgacagccgt tctcgccgta ttaaaggcag
    21601 gcggagctta tgtgccgctt gatcctgtat atccagagga gcggctgagc tatatgctga
    21661 aagacagcgg ggcagcattg t
//
