LOCUS       NZ_PVTF01000018        21923 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Umezawaea tangerina strain DSM 44720 Ga0180964_118, whole genome
            shotgun sequence.
ACCESSION   NZ_PVTF01000018
VERSION     NZ_PVTF01000018.1
KEYWORDS    WGS; RefSeq.
SOURCE      Umezawaea tangerina
  ORGANISM  Umezawaea tangerina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Umezawaea.
REFERENCE   1  (bases 1 to 166491)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 166491)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Expected Final Version            :: No
            Genome Coverage                   :: 86.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003002815.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:47:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,483
            CDSs (total)                      :: 9,418
            Genes (coding)                    :: 9,322
            CDSs (with protein)               :: 9,322
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 20 of 97
            Pseudo Genes (incomplete)         :: 83 of 97
            Pseudo Genes (internal stop)      :: 2 of 97
            Pseudo Genes (multiple problems)  :: 8 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 144568
            Orig. end                         :: 166491
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVTF01000018.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21923
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="3"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..21923
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21923
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:>21923](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>21923
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     misc_feature    complement(239..254)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.13"
                     /tool="antismash"
     misc_feature    complement(352..366)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     misc_feature    389..403
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.09"
                     /tool="antismash"
     misc_feature    1828..1845
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.28"
                     /tool="antismash"
     misc_feature    complement(1992..2003)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.37"
                     /tool="antismash"
     misc_feature    complement(2170..2184)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.12"
                     /tool="antismash"
     misc_feature    2206..2219
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.1"
                     /tool="antismash"
     misc_feature    2206..2222
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.86"
                     /tool="antismash"
     misc_feature    complement(2220..2233)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.35"
                     /tool="antismash"
     gene            complement(2402..2749)
                     /gene="crcB"
                     /locus_tag="CLV43_RS41645"
                     /old_locus_tag="CLV43_118138"
     CDS             complement(2402..2749)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:1903425 - fluoride transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:1903424 - fluoride transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crcB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660238.1"
                     /locus_tag="CLV43_RS41645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118138"
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="WP_106195658.1"
                     /transl_table=11
                     /translation="MTVLAVVLGAAVGAPLRYLVGRALNGRFPHGTLLANTAGSGLLGF
                     LVALPADPTTLALLGTGFCGALTTYSTFSLETLRLVEERAHRAALVNVLASLALGLLAA
                     YAGMALATTIG"
     gene            complement(2746..3102)
                     /locus_tag="CLV43_RS41650"
                     /old_locus_tag="CLV43_118139"
     CDS             complement(2746..3102)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017985603.1"
                     /locus_tag="CLV43_RS41650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118139"
                     /product="CrcB family protein"
                     /protein_id="WP_245887422.1"
                     /transl_table=11
                     /translation="MALRVLGAVACGGALGALARYGLGVAFPYGPWTVLVVNATGCLLI
                     GVLMGLTEDVLLRTFLGTGVLGGYTTFSTYVVDFQRFASQGRPAIAVAYLGGTLALALL
                     AVYSGTALAGRVRR"
     gene            complement(3119..3547)
                     /locus_tag="CLV43_RS41655"
                     /old_locus_tag="CLV43_118140"
     CDS             complement(3119..3547)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02246.1"
                     /locus_tag="CLV43_RS41655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118140"
                     /product="SgcJ/EcaC family oxidoreductase"
                     /protein_id="WP_106195662.1"
                     /transl_table=11
                     /translation="MSELLDTTRTLSYWPEVGEISALFGDWNAALATGDPYRVADRYTP
                     DAVLLPTMSADVRTDRAGIVDYFAGFMLARPLAVVKRSFVRVLRSTEAIDSGLCRFTMK
                     KGGHTVAMDARFTFVYEKIDGKWMIVTHHSSAVPSEGV"
     misc_feature    complement(3519..3535)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.23"
                     /tool="antismash"
     gene            complement(3659..4090)
                     /locus_tag="CLV43_RS41660"
                     /old_locus_tag="CLV43_118141"
     CDS             complement(3659..4090)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098991.1"
                     /locus_tag="CLV43_RS41660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118141"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_106195664.1"
                     /transl_table=11
                     /translation="MSEEARTLTDVVTRLRRALRTSIRSDWPWESLPMAQIELLQTLAE
                     RPPMRVGDLAAELRLAPNTVSGLVGQLIDSGLVSRAGDPADRRVARLSVTAQGHDQLAV
                     WQSAHEKRIGAALDKLDVQERADVVRALTALDHLVDHLR"
     gene            4144..5523
                     /locus_tag="CLV43_RS41665"
                     /old_locus_tag="CLV43_118142"
     CDS             4144..5523
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020497757.1"
                     /locus_tag="CLV43_RS41665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118142"
                     /product="MFS transporter"
                     /protein_id="WP_106195666.1"
                     /transl_table=11
                     /translation="MDHATRGWRWFVAESPRPRRIATWAGASRLVIATVCFGAFMGQFD
                     ASIVTLAFPALADHFGAPPAAVEWVSLSYLLALVALLAAVGRLADVIGRKLVYVYGFAV
                     FTAASAACALAPDLTSLVVFRVVQGVGAAMLQANSVALVVACVPRDRMRGALGVQAAAQ
                     ALGLALGPTVGGVLVGALGWRSVFAINIPIGVVAVVAGHYLLPRTVDRAEPGRFDLAGT
                     LLLGTATTAALLVLSGVSGLAVPVLPLVAVAVAATAALWWWERRAGTPLLDLALLRRAP
                     ISRGLLGALCGYLVLFGPLVAVPFASTGSPLATGLTLTALPAGFALAATLGQRVLPGSW
                     TTARVGAWLAAAATLVPVVAPGALVPALALLGFGLGVFTPANNAAVMAALPAGQAGLGG
                     GLVNTTRGLGTALGIAVSTFVLHTGGAHALRTTFAVLAVVAVVSALSTPVLRTGEGATG
                     R"
     gene            5567..6367
                     /locus_tag="CLV43_RS41670"
                     /old_locus_tag="CLV43_118143"
     CDS             5567..6367
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018682258.1"
                     /locus_tag="CLV43_RS41670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118143"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_106195668.1"
                     /transl_table=11
                     /translation="MELANWVPDDVDTGLPSAARLYDYLLGGGHNFAGDRALGEQFLKA
                     QPNARAIARLNRAFLRRAVLFMIDNGIRQFLDLGSGIPTVGNVHEVARRAAPESRVVYV
                     DFEDIAVAHSRMMLADDPLATIVQQDLTEPEVVLEAALGTGLVDRAEPLGVLAVGVFHF
                     VPPERHPEAVVAAYRDAVVPGSHLALSQFTADLQPVEMAGIVEVMKKSMNPMFPRTLAE
                     ITGLFAGFDVVEPGVVPLPLWRPEGLSDDDPAKAGILGGVGRKR"
     misc_feature    complement(6402..6415)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.68"
                     /tool="antismash"
     gene            6411..8507
                     /locus_tag="CLV43_RS41675"
                     /old_locus_tag="CLV43_118144"
     CDS             6411..8507
                     /EC_number="2.7.7.65"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098989.1"
                     /locus_tag="CLV43_RS41675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118144"
                     /product="diguanylate cyclase"
                     /protein_id="WP_106195670.1"
                     /transl_table=11
                     /translation="MTPPDQPHGRRRELAREWMKAVYSTTYIPMSSAEIELFLLDLVDV
                     IADALRAEPFTAKPVAVVGDRMVAAHFTGMETLQRTVEVLGRALLFTPELRGVDRLAEK
                     VVAVLGALGARFATAMRLDAFRQQEEIKSALLQAKQGVERVLRVSEARFREVFDSSVMG
                     IAITEPDGTVVEANEAMNAILGSERSLIGRSLPRHFHPDDAEVLTASYRSVREGVVDRF
                     REQRRLVRIDGEPAWVYLAVSVLRDADGEPAFHVTMVEDVSELHLMQKNLDSLLLRDPL
                     TGLSNRQHFVTQLETVHSRSEHGITLYHLDLDSFSLINNGLGHDTGDRLLKQTASRLRA
                     VVADQDAFVARIGGDEFAVVVDNSPTTPGVPTMIDKINDELAEPTFVDDRGIAVTATIG
                     VLDRPSPEWTVGQLLRAANMTLTLAKAKGKRQWLPYDPHEDARQRAAARVTAALPGAFE
                     NGELEVDFHPVVGLADRTVVGVSARLRWGSLGHRQCLAMADETGLSLPVGQWMLRYAAE
                     RVVLWREATGVTPLPLHVALSPMQSRDEDLVGAVKRTLDETGLPVGDLRISLHTRAVLI
                     GGSDDNVQVLTDSGIPTGLNDFHGGQDELALLTELPIHSLTIAPATVRALADRTARNPL
                     AHNAMASLVAVVRQAGVSVTAAGVTTDAEADWWAGIGTDAAQGDFYTASRTTGPLAALF
                     QDRP"
     misc_feature    8088..8090
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8504..8878)
                     /locus_tag="CLV43_RS41680"
                     /old_locus_tag="CLV43_118145"
     CDS             complement(8504..8878)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV43_RS41680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV43_118145"
                     /product="VOC family protein"
                     /protein_id="WP_211304812.1"
                     /transl_table=11
                     /translation="MTLVLNHTIVRATDKDVSAAFFAGLVGREVGEPAGPFTPVRVNDD
                     LTLDFDERPPFSAGHFGFLVDDTTFDHLLARLESDVDVRFGSGPGGGWDRRINRLAGGR
                     GVYVADPDGHSYEFFTTVPA"
     gene            8950..9372
                     /locus_tag="CLV43_RS41685"
                     /old_locus_tag="CLV43_118146"
     CDS             8950..9372
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020416633.1"
                     /locus_tag="CLV43_RS41685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118146"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_106195674.1"
                     /transl_table=11
                     /translation="MPSNDGGPALFRLVRFWSRRWAKGSEGDASHAQLVLTVEAVAASG
                     TDGSVGDVARLLGLDQSGASRMVAAAEAGGYVDRARAASDARRSALRLTPGGRALLRSA
                     RGWQRSTFAELTATWPEEDRDRFAAYLRRLADQVGA"
     gene            complement(9373..10725)
                     /locus_tag="CLV43_RS41690"
                     /old_locus_tag="CLV43_118147"
     CDS             complement(9373..10725)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630485.1"
                     /locus_tag="CLV43_RS41690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118147"
                     /product="NAD(P)(+) transhydrogenase (Re/Si-specific)
                     subunit beta"
                     /protein_id="WP_106195676.1"
                     /transl_table=11
                     /translation="MSAQLAYLVAALCFLLALKGLSTPRFARAGNLLGAAGMVLAVVTA
                     FVQGAVHNGLWILVAIALGAVVAVPAARSVKMTAIPQMVALFNGVGGAAAALVALAEFH
                     DGGPLLFRIATVLTVLIGSGSFSGSLVTFAKLQEIMTTRPVVLPAGRVLSIGVVAVSLV
                     LAVAVLATSSTALLVALTVAGLLLGIAFVLPVGGADVPIAISLLNAFTGLAVAASGYVL
                     ANTLLIVAGTLVGASGTLLTRMMAQAMGRPLTNILFGAFTATAVQVRGEEQRTVRSGTV
                     EDVAILLGYAHSIVVVPGYGLAVAQAQHAARELVTLLEGRGITVDYGIHPVAGRMPGHM
                     NVLLAEADVPYEQLKELDDVNPGMTSMDVALVVGANDVVNPGARDEPTSPIYGMPIFDV
                     DRARAVVFMKRSMRPGFAGIDNELLYNAKTTLLFGDAKDSLTKLLAAVKQL"
     gene            complement(10722..10997)
                     /locus_tag="CLV43_RS41695"
                     /old_locus_tag="CLV43_118148"
     CDS             complement(10722..10997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671372.1"
                     /locus_tag="CLV43_RS41695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118148"
                     /product="NAD(P) transhydrogenase subunit alpha"
                     /protein_id="WP_245887423.1"
                     /transl_table=11
                     /translation="MIDLLTIFVLAAFVGFEVVSKVSTILHTPLMSGANAIHGVILVGA
                     ILITGAAEGAVQLVLGLLAVFLATVNVVGGFVVTDRMLEMFKGHKR"
     gene            complement(10994..12103)
                     /locus_tag="CLV43_RS41700"
                     /old_locus_tag="CLV43_118149"
     CDS             complement(10994..12103)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800146.1"
                     /locus_tag="CLV43_RS41700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118149"
                     /product="NAD(P) transhydrogenase subunit alpha"
                     /protein_id="WP_106195678.1"
                     /transl_table=11
                     /translation="MRVGIPAESRPAERRVACVPDTVRTLVGAGLVVDVQSGAGTHAYA
                     ADAAYRAAGAQVVAQDTVGEVEAVLSVQPLEIAQARRLRPGDITISFLSPPNELELVRV
                     LAERGVTSFSLDLLPRVTRAQGADALSSQALVAGYRAVLVAAERLPRFLPMFTTAAGTV
                     PPAKVLVLGAGVAGLQAIATARRLGAVVEAYDVRAAAAEEVRSLGARFVELPLETQQGV
                     YAAEQSETFLERQRELIAERVAASDVVITTAAIPGRAAPVLVTTDMLKAMAPGSVVVDL
                     AAESGGNCAGSVAGQEVWVGDVLVHGARNMPSGMPIHASKLYARNVANLLMMMTEDGVV
                     EPDLTDEVLAGCCLTHAGEVRHEPTRGLL"
     misc_feature    12127..12142
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.99"
                     /tool="antismash"
     gene            complement(12703..13854)
                     /locus_tag="CLV43_RS41705"
                     /old_locus_tag="CLV43_118150"
     CDS             complement(12703..13854)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800145.1"
                     /locus_tag="CLV43_RS41705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118150"
                     /product="nitric oxide synthase oxygenase"
                     /protein_id="WP_245887424.1"
                     /transl_table=11
                     /translation="MPLPPSLVENAVAVPATEVDIAEAEEFIRLHHEENHDLGPVEDRL
                     AEVHAEIAATGTYRHTTTELTFGARVAWRNSARCIGRLYWRSLKVRDLRDLHDPKEVAD
                     ECVEHLRIATNAGKIRPVMTVFAPDEPGHPGPRVRNEQLIRYAAYRGPDGGVLGDRRNL
                     ELTDLAITRGWQPPRTRGPFDVLPVLVETSDGESGMVDLPPDAVLEVPLSHPELPWLAK
                     LGLRWHAVPVISNMRMRIGGIDYPAAPFNGWYMGTEIGARNLADNDRYDLLPYLGKRMG
                     LDTSCEQTLWRDRALVELNRAVLHSFAEAGVTITDHHTESQRFLTHVQKEEAAGRKCPT
                     DWTWIVPPMSGSLTPVFHRYYDKEEQVPNFFPNGTTGVCPVIH"
     gene            14173..14745
                     /locus_tag="CLV43_RS41710"
                     /old_locus_tag="CLV43_118151"
     CDS             14173..14745
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013718.4"
                     /locus_tag="CLV43_RS41710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118151"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_106195682.1"
                     /transl_table=11
                     /translation="MIELSAALYLFITGIAHETPDWVHTIADIGTDAGLLVFVALFAWN
                     AWRNRGTPEYRLALVAPLAVIGAYLVSEVAKTFIQEERPCRAVAGAVFIAECPAVGDWS
                     FPSNHATIAAACAAVLATVWGRVALLVFPLAMLMAFSRVFVGVHYPHDVAAGFLVGATV
                     GALLALLAVRLVGPAKAAPRVPVGSRR"
     gene            complement(14687..15853)
                     /locus_tag="CLV43_RS41715"
                     /old_locus_tag="CLV43_118152"
     CDS             complement(14687..15853)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007026282.1"
                     /locus_tag="CLV43_RS41715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118152"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_106195684.1"
                     /sec_met_domain="Trp_halogenase (E-value: 1.6e-06,
                     bitscore: 20.5, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGTAVVVGGGLGGLTAAVALHRVGWRVTVLERAPEFGEVGAGIG
                     VMPNALRALDALGLGEAVRHDGTPRLPGGVRDHRGRALGHLDAAELERAGRLVAIHRAD
                     LHRVLRSALPAECLVTSADVVEVVPRVRYLADGDPVELEADLVVAADGIGSRVRSRLWP
                     EVPAPVYSGTTAWRAVTDHTGDLEIGQYLGPGTEFGVLPLAAGRVYWYAATLSAPGLRA
                     PDELAEVVRLCGDWADPIPALLAGTPGGSVLRHDVHELAAPPSTYVHGRVALLGDSAHA
                     MTPFLGQGACQAIEDGVVLAAACADADTVAAALTRYDRERGPRTRSVARASRLMGRVGH
                     GLRHPAAVAVRNALMRSVPTGVALSGMTRFSAWTPPALAAPPSPDRPV"
     misc_feature    15868..15883
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.08"
                     /tool="antismash"
     gene            15922..16536
                     /locus_tag="CLV43_RS41720"
                     /old_locus_tag="CLV43_118153"
     CDS             15922..16536
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037009.4"
                     /locus_tag="CLV43_RS41720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118153"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_211304813.1"
                     /transl_table=11
                     /translation="MSDRTDLLADAAIHVVATHGMRGLTHRAVDARAGVPQGSTSAYFR
                     TRKALVEGLVRRLADVETADIDATRLTSQTSDGPPDLDRVAAGVAALLDHWLGAGRDRS
                     LARFACLLEATHHPELRTILAYGDRPRAQARELVAALGSTDPERDGHDLVSFVDGLLFY
                     RLAGGGAAHAPAPGTPESLAELHRAALAALTGVLARRSPAR"
     gene            16749..18329
                     /locus_tag="CLV43_RS41725"
                     /old_locus_tag="CLV43_118154"
     CDS             16749..18329
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672076.1"
                     /locus_tag="CLV43_RS41725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118154"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_245887425.1"
                     /transl_table=11
                     /translation="MRARLVQPRHAHLRTEDLGKGFEARPVLSGVHLTASTGQRLGVIG
                     ENGRGKSTLLRLLAGDLEPDAGTVTRHGSVATAAQELPFTADDTVGTLLDHALAPARAA
                     VAEVDGAAAALADAEPGADDRYAVALAEAERLEAWDAERRADLALAALDAPADRALRLA
                     ELSVGQRYRVRLACVLAERADILLLDEPTNHLDASGMAYLTARLREHQGVVVLVSHDRA
                     LLDEVCTALLDLDPNAEGEVVLHGGGYSAYRSAKAAERARWEQRYALEASRDAELREQV
                     SAAEARLVTSWRPPKGAGRHKRATRAPSRMRTVARRLEELTDRRVPEPPAPLRFASPDL
                     EAGPDEVLLGASGVTVPGRLRPHPDLAVAAGGRLVVSGANGTGKSTLLGVLAGRVVPAS
                     GAVHRGGRTRIGLLAQESDFPDPSLSPVRLAGGDAEPLRGLGLLADVDLTRPVGRLSTG
                     QRRRLSLALLLLRAPHVLLLDEPTNHLSIALVDELTEALLVTAAAVVVATHDRRLRADL
                     GDWPELELI"
     gene            18406..19608
                     /locus_tag="CLV43_RS41730"
                     /old_locus_tag="CLV43_118155"
     CDS             18406..19608
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800144.1"
                     /locus_tag="CLV43_RS41730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118155"
                     /product="cytochrome P450"
                     /protein_id="WP_106195736.1"
                     /sec_met_domain="p450 (E-value: 2.8e-26, bitscore: 85.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTITAALPTTRDNAFDPPAELGVLREERPLNRLQFPDGHVGWL
                     VTNHELVREIMADRRFSSRSELHHSVITRADGKPVRRPAATPGMFIGMDAPDHTRYRKL
                     LTGQFTVRRMNLLSARIEEIVQEHLKAMRANGTSGDLVQAFALPIPSLVICELLGVPYD
                     ERHGFQEDTATALRLETSADEAIAAFERIKDFIRDLVRRKRANPGDDMLSGLIASGEHL
                     DDEEITGMGVLLLVAGHETTANMLGLGTLALLGNPDQLAALKADPSLVDNTVEELLRYL
                     SIIQFGTTRTALEDVEIAGEVIKEGDTLSLSLAAANRDPQRFDHPDRLDVHRSANGHMS
                     FGHGVHQCLGQQLARIEMRIAYSALFAEFPDLRLAVPADEVPLRTDMAIYGVHSLPVEW
                     S"
     gene            19605..19799
                     /locus_tag="CLV43_RS41735"
                     /old_locus_tag="CLV43_118156"
     CDS             19605..19799
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098978.1"
                     /locus_tag="CLV43_RS41735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118156"
                     /product="ferredoxin"
                     /protein_id="WP_106195688.1"
                     /transl_table=11
                     /translation="MRIEADVNKCCGSGMCALTDPELFDQSEEDGTVLVLVSEPGPEHH
                     AAAREAAALCPAGAITVHG"
     misc_feature    complement(19977..19990)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.37"
                     /tool="antismash"
     gene            20001..>21923
                     /locus_tag="CLV43_RS41740"
                     /old_locus_tag="CLV43_118157"
     CDS             20001..>21923
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (3-30). E-value:
                     1.6e-16. Score: 51.6. Matches aSDomain:
                     nrpspksdomains_CLV43_RS41740_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-460). E-value:
                     5.1e-178. Score: 584.2. Matches aSDomain:
                     nrpspksdomains_CLV43_RS41740_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441172.1"
                     /locus_tag="CLV43_RS41740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_118157"
                     /product="type I polyketide synthase"
                     /protein_id="WP_146175116.1"
                     /sec_met_domain="mod_KS (E-value: 9.1e-220, bitscore:
                     723.0, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.6e-90, bitscore:
                     296.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.2e-22, bitscore: 71.8,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNEQKLRDYLRRVTADLHSTRHRLQEVEGTGQEPIAIVAMGCRF
                     AGGITSPEELWDFVVDGGDAVAPFPTDRGWDLEALYHPDPDHQGTSYVMEGAFVDGVAE
                     FDPGFFGISPREAITMDPQQRLLLETTWHTFERAGIDPHALRGSRTGVFTSTNGQDYIT
                     KLQGELPDGLEGHVGTGTAASMISGRISYTFGLEGPAVTVDTACSGSLVTLHLAVQALR
                     NGECDLALAGGATIMVTPGAFIDFSRARGLSWDSRCKSFAAGADGTSWGDGVGLVLVER
                     LSDARRNGHEVLAVVRGIAVNQDGASNGLTAPNGPSQQRVIKQALADARLSAVDVDVIE
                     AHGTGTKLGDPIEAQALIAAYGPERETPLLLGSVKSNIGHTQAAAGVAAVIKTVMALRH
                     GVVPKTLHVDAPSPQIDWSSGTAELVTETRAWPETGHVRRAGVSSFGYSGTNAHAILEQ
                     APEDPLDVEGDEPAAAPRELPVVPVLLSGKTEQAVRAQAAALLESLPGNDLADLGFSTA
                     TTRAHLDHRAVLVADDRDGLLAALGALADGTAPVAGEAVEGRTAVLFTGQGSQRVAMGQ
                     QLYSAFPVYAEAFDAVCDRFDPRLREAFADQDLLNRTEFTQPALFAVEVALYRLVESWG
                     VRPDFL"
     aSDomain        20010..20090
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLV43_RS41740_PKS_Docking_Nterm.
                     1"
                     /evalue="1.60E-16"
                     /label="CLV43_RS41740_PKS_Docking_Nterm.1"
                     /locus_tag="CLV43_RS41740"
                     /protein_end="30"
                     /protein_start="3"
                     /score="51.6"
                     /tool="antismash"
                     /translation="EQKLRDYLRRVTADLHSTRHRLQEVEG"
     aSDomain        20106..21380
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLV43_RS41740_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="5.10E-178"
                     /label="CLV43_RS41740_PKS_KS.1"
                     /locus_tag="CLV43_RS41740"
                     /protein_end="460"
                     /protein_start="35"
                     /score="584.2"
                     /tool="antismash"
                     /translation="IAIVAMGCRFAGGITSPEELWDFVVDGGDAVAPFPTDRGWDLEAL
                     YHPDPDHQGTSYVMEGAFVDGVAEFDPGFFGISPREAITMDPQQRLLLETTWHTFERAG
                     IDPHALRGSRTGVFTSTNGQDYITKLQGELPDGLEGHVGTGTAASMISGRISYTFGLEG
                     PAVTVDTACSGSLVTLHLAVQALRNGECDLALAGGATIMVTPGAFIDFSRARGLSWDSR
                     CKSFAAGADGTSWGDGVGLVLVERLSDARRNGHEVLAVVRGIAVNQDGASNGLTAPNGP
                     SQQRVIKQALADARLSAVDVDVIEAHGTGTKLGDPIEAQALIAAYGPERETPLLLGSVK
                     SNIGHTQAAAGVAAVIKTVMALRHGVVPKTLHVDAPSPQIDWSSGTAELVTETRAWPET
                     GHVRRAGVSSFGYSGTNAHAILEQAP"
     CDS_motif       20361..20387
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CLV43_RS41740_0001"
                     /evalue="8.10E-03"
                     /label="PKSI-KS_m2"
                     /locus_tag="CLV43_RS41740"
                     /protein_end="129"
                     /protein_start="120"
                     /score="9.1"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       20592..20636
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CLV43_RS41740_0002"
                     /evalue="5.00E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="CLV43_RS41740"
                     /protein_end="212"
                     /protein_start="197"
                     /score="18.5"
                     /tool="antismash"
                     /translation="GPAVTVDTACSGSLV"
     CDS_motif       21015..21059
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CLV43_RS41740_0003"
                     /evalue="6.80E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="CLV43_RS41740"
                     /protein_end="353"
                     /protein_start="338"
                     /score="14.6"
                     /tool="antismash"
                     /translation="IEAHGTGTKLGDPIE"
     CDS_motif       21114..21158
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CLV43_RS41740_0004"
                     /evalue="1.80E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="CLV43_RS41740"
                     /protein_end="386"
                     /protein_start="371"
                     /score="13.6"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       21690..21737
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CLV43_RS41740_0005"
                     /evalue="1.40E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="CLV43_RS41740"
                     /protein_end="579"
                     /protein_start="563"
                     /score="17.5"
                     /tool="antismash"
                     /translation="FTGQGSQRVAMGQQLY"
     CDS_motif       21831..21890
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CLV43_RS41740_0006"
                     /evalue="4.40E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="CLV43_RS41740"
                     /protein_end="630"
                     /protein_start="610"
                     /score="16.5"
                     /tool="antismash"
                     /translation="NRTEFTQPALFAVEVALYRL"
ORIGIN
        1 ggccgcgagt cgccggaggc cgccgcgatc aagggccgca tcacgatggc ggacgtgatc
       61 tcgcacgcga tcaaggaccg gcaggaggcg ccgggcatga tcgaggtgcc gttcgagcag
      121 gagaccctgc ggctggaccg gcgggccatc accgaggcgc gcggccgggc gcggcgcacc
      181 cgcaggccgc acaacgaggc caggcggacg ttcgtccggg agatgatctc cacgatggcg
      241 aaccaggcgg tcaacaagct gggcaggcac ctgctcgacg ccgacgacat cgacgagatc
      301 cgccgcgagc tgcgcgagga cgagaacgtg cagaacgcgc tcgcccggct ctggccgacg
      361 ctcaccccgc agcagctgct gtccgagctg ttctcctcgg ccaagcggct cgccaccgcc
      421 gccccgcgga tgagcaagga ggaccgggcg ctgctgctgc gcgaaccgga cgccgagtgg
      481 acgcccgccg acgtgccgct gctggacgag gccgcggagc tgctcggcga ggacgacgcg
      541 gacgccaagg cgcgcgccga acgccagcgg cggcaggcca tcgactacgc gcagggcgtg
      601 ctggacatcc tcgacctcga ggacgacgcc gaccccgaga tcctgatggc gcacgacctg
      661 atggacgcct accggctcgc cgagcggcac ggcggcgaga actacgagac cgccgccgaa
      721 cgcgccgcgg ccgaccggac gtggacgttc gggcacatca tcgtggacga ggcgcaggag
      781 ctgtcggcga tggcgtggcg gacgctgatg cggcgctgcc cgagcaagtc gatgaccgtc
      841 gtcggggaca tcgcgcagac cggggacatc gcgggcgcga cgtcgtgggg gcaggtgctc
      901 tcgccgtacg tgatggaccg gtggaagctc accgagctga ccgtgaacta ccggacgccg
      961 tcggagatca tggccgtggc ggccgacgtg ctggcgagcg tggaccccga gctggtgccg
     1021 ccgacgtcgg tgcgcgacag cggcgtggaa ccctggcacg cgcaggtccg cgacctggtg
     1081 gccgacctgc cggggctggt ggcgcgggag gcgggggaga tcggcgaggg gaagctcgcc
     1141 gtgatcgtcc ccgcggccag ggtggcggac ctgggagagg cgatcaccgc ggcgatccca
     1201 ggagcggctg tcggcagcca gtcggcggcg ctggacgcgc gggcggtggt gctgggggtg
     1261 gtcgacgcga aggggctgga gttcgacgcc gtcgtggtgg tggacccggc ggggatcctg
     1321 gcggagtcgc cccggggggc cagtgacctg tacgtggctc tgacgcgggc tactcagcgg
     1381 ttgggggtcg tgcacgaggg tgggttgccg ggggtgttga gccggttgaa gggggcgtcg
     1441 gtgttggggt gacggggccg aagcggggtg tcgggatccg tcgagctcga caccgggtgt
     1501 cgctgcgagc tcgacaccgg gtgtcgctgc ggtggtctcc gggtgcggcc gacttgactt
     1561 ggggcccctt ttttgggctt cgtcgggcga aaaagggcag gtggtagagc ctgcccgccg
     1621 ccgcaagtct aagcccaaaa accccaagtc aagtcggccg cacgggcgga cgggtgggct
     1681 cgccggggtc gtgggtgggg tgtgcgctcg gtctcgtggt ggtgggcagg ttggctcggg
     1741 tgggtgctgg tgctggtggg cgagttggct cggtgggtgg ctcgcgcgtg aggtctggtg
     1801 gggctgcttg gagcgctccg gggtcaattg gtagcggggt gtgaaaaagg gctgttgagg
     1861 ccacgcagag ggtggtggcc tcaacagccc gtgacgagcg ggggcagctc gttgggtggt
     1921 tattgttctt gtgcggaccg aggaactcag gggttccggt attgctggaa tctcttcgtc
     1981 cgatcggaat aaataacgtt gtcagcgcac gcggtgcttg tcgtcggtga cctgaagagg
     2041 catgctccgg ggcagggagc tgcgacttca cggtcagacc cgtgggtctt gaactgctat
     2101 gccgtcgtct gggtcatgag gttgggcctt tcgacggaac gtgacgcacg tgcatctgcg
     2161 agcgcatcca ggtatctgac aatgtaatct cttaccccgc ccaggacgtt acaaaagaac
     2221 tgtagtaatt ctggttgcgc caattggagc aattgattga accgcgtgcc gggggttgtc
     2281 ggggccaccg cagagggtgg cagccccgac agtcccgagt acgccccccg aggacgggct
     2341 tgttcggtca acgagcgggg ttgcgcgggg aaacgggtgg gaggtctcgg gtcggtgacg
     2401 gctacccgat cgtcgtagcg agggccatgc cggcgtaggc ggcgagcagg ccgagggcga
     2461 ggctggcgag gacgttcacc agggcggcgc ggtgagcgcg ttcctcgacc aggcggaggg
     2521 tctccaggct gaaggtggag taggtggtga gcgcgccgca gaagccggtg cccagcaggg
     2581 cgagggtggt ggggtcggcg ggcagggcga cgaggaagcc gaggaggccg gagcccgcgg
     2641 tgttggcgag cagggtgccg tgggggaagc ggccgttgag ggcgcggccg acgaggtagc
     2701 gcaggggggc gccgacggcg gcgcccagga cgacggcgag gacggtcatc ggcgcacccg
     2761 cccggccagg gcggtgcccg agtagacggc gagcagggcc agggccaggg tgccgccgag
     2821 gtaggcgacg gcgatagcgg gtcgtccctg ggaggcgaac cgctggaagt cgacgacgta
     2881 ggtggagaac gtcgtgtagc cgcccagcac cccggtgccg aggaacgtgc ggagcagcac
     2941 gtcctcggtc agccccatca gcacgccgat gagcaggcac ccggtggcgt tgaccacgag
     3001 gacggtccac ggcccgtacg ggaaggcgac gccgagcccg tagcgggcca gcgccccgag
     3061 cgccccgccg cacgcgacgg cgccgagcac ccggagcgcc acgatccctc ccgaggggtc
     3121 agaccccctc ggacggcacg gccgaggagt ggtgggtcac gatcatccac ttcccgtcga
     3181 tcttctcgta gacgaaggtg aagcgggcgt ccatcgcgac ggtgtgcccg cccttcttca
     3241 tggtgaagcg gcagaggccg gagtcgatgg cctcggtcga gcgcagcacc cggacgaacg
     3301 acctcttcac cacggcgagt ggtctggcca gcatgaagcc cgcgaagtag tcgacgatgc
     3361 ccgcgcggtc cgtgcgcacg tcggcggaca tcgtcggcag cagcacggcg tccggggtgt
     3421 accggtcggc gacccggtac gggtcgccgg tggccagcgc cgcgttccag tcgccgaaca
     3481 gggcggagat ctcccccacc tcgggccagt aggagagggt gcgagtggtg tccagcagtt
     3541 cgctcattgc ggttctcccc gacggcagag gacgtgtctt gcgtccactg tcgactcgcg
     3601 gagccctccc gacatcccct agacgccgtt caaacacccc agagaaaatc taggggggtc
     3661 agcgcaggtg gtccaccagg tggtccaggg cggtcagcgc gcggaccacg tcggcgcgct
     3721 cctggacgtc cagcttgtcc agcgcggcgc cgatccgctt ctcgtgcgcg ctctgccaca
     3781 cggccagctg gtcgtgcccc tgcgcggtca ccgacagccg cgcgacccgg cggtcggcgg
     3841 ggtcgccggc gcgggagacc aggcccgagt cgatcagctg gccgaccagt ccgctgaccg
     3901 tgttcggggc cagccgcagc tcggcggcca ggtcgccgac ccgcatgggc ggccgttcgg
     3961 cgagtgtctg gagcagctcg atctgggcca tcgggagcga ctcccacggc cagtccgacc
     4021 ggatgctcgt ccgcaacgcc ctgcgcagcc gggtcaccac gtcggtgagc gtccgggcct
     4081 cttctgacat gggggcagat tactgatccg acatacctcg gactccgata tgatcggggt
     4141 ccgatggatc atgcgacgcg gggctggcgg tggttcgtcg cggagtcacc acgtccgcgg
     4201 cggatcgcga cctgggcggg cgcgtcccgg ctggtgatcg cgacggtgtg cttcggcgcc
     4261 ttcatgggcc agttcgacgc gagcatcgtc acgctggcgt tccccgcgct ggccgatcac
     4321 ttcggagccc cgcccgcggc cgtcgagtgg gtctcgctgt cctacctgct ggcgctggtc
     4381 gcgctgctgg ccgccgtcgg gcggctggcg gacgtgatcg gccgcaagct ggtctacgtc
     4441 tacgggttcg ccgtgttcac cgccgcgtcg gcggcctgcg cgctcgcgcc ggacctgacg
     4501 tcgctggtcg tgttccgggt cgtgcagggc gtcggcgcgg cgatgctcca ggccaacagc
     4561 gtggcgctgg tcgtggcctg cgtgccgcgc gaccggatgc gcggggcgct cggcgtgcag
     4621 gcggcggcgc aggccctcgg actggcgctg ggacccacgg tgggcggtgt gctcgtcggc
     4681 gcgctgggct ggcgctcggt gttcgcgatc aacatcccga tcggcgtggt ggccgtggtc
     4741 gccgggcact acctgctgcc gcgcacggtc gaccgcgccg agcccggccg gttcgacctc
     4801 gcgggcacgc tgctgctcgg cacggccacc accgccgcgc tgctcgtgct gtccggcgtg
     4861 tcaggtctcg ccgtgccggt gctcccgctg gtggccgtcg cggtcgcggc cacggcggcg
     4921 ctgtggtggt gggagcgccg ggcgggcacg ccgctgctgg acctcgcgct gctgcgccgg
     4981 gcgccgatca gccgcggcct gctcggcgcg ctgtgcggct acctcgtgct gttcggacca
     5041 ctggtagcgg ttccgttcgc gagcaccggg tcgccgttgg ccaccgggct gacgctcacc
     5101 gccctgcccg ccgggttcgc cctcgcggcg accctgggcc agcgggtgct ccccggctcg
     5161 tggacgacgg cacgggtggg cgcctggctg gcggcggcgg ccacgctggt gcccgtcgtc
     5221 gcacccggcg cgctggtgcc cgcgctggcg ctgctggggt tcggcctcgg cgtcttcacc
     5281 cccgccaaca acgccgcggt catggcggcg ctgcccgccg gacaggccgg tctgggtggc
     5341 ggcctggtca acaccacgcg aggcctcggg acggcgctcg ggatcgcggt cagcacgttc
     5401 gtcctgcaca ctgggggtgc ccacgcgctg cgcacgacgt tcgccgtgct ggccgtggtc
     5461 gccgtcgtgt ccgccctgtc aacaccggta ctccgaaccg gtgagggcgc caccggtcgg
     5521 tagcttctac gccagtaccc cgacgacgcg gacgggaggt tgtgcggtgg aactggcgaa
     5581 ctgggtgccc gacgacgtcg acaccggcct cccgagcgcg gcccggctct acgactacct
     5641 gctcggcggc ggccacaact tcgcgggcga ccgggcgctg ggcgagcagt tcctcaaggc
     5701 ccagccgaac gcccgcgcga tcgcccgcct caaccgcgcg ttcctgcgcc gcgccgtgct
     5761 gttcatgatc gacaacggca tccgccagtt cctggacctc gggtccggca tcccgaccgt
     5821 cggcaacgtc cacgaggtcg ccaggcgcgc cgccccggag tcgcgggtcg tgtacgtcga
     5881 cttcgaggac atcgcggtgg cgcacagccg gatgatgctg gcggacgacc cgctcgccac
     5941 gatcgtgcag caggacctga ccgagcccga ggtggtgctg gaggccgcgc tgggcaccgg
     6001 tctggtcgac cgcgccgagc cgctgggcgt gctggccgtc ggcgtcttcc acttcgtccc
     6061 gccggagcgg cacccggagg cggtggtggc cgcctaccgc gacgccgtcg tgcccggcag
     6121 ccacctggcg ctctcgcagt tcaccgcgga cctgcagccc gtggagatgg ccgggatcgt
     6181 cgaggtgatg aagaagagca tgaaccccat gttcccgcgc accctggcgg agatcacggg
     6241 cctgttcgcc gggttcgacg tggtcgagcc gggggtcgtg ccgctgccgc tgtggcggcc
     6301 ggaagggctc tccgacgacg accccgcgaa ggccgggata ctcggaggcg tgggccgcaa
     6361 gcggtgaccg cccccgatcc gcgaagacca ccggctcggg gggacggagc gtgacgccgc
     6421 cggaccagcc gcacggacgt cgacgggagc tcgcccgcga gtggatgaag gccgtctact
     6481 ccacgaccta catcccgatg tcgtcggccg agatcgagct gttcctgctc gacctggtgg
     6541 acgtgatcgc cgacgcgctg cgggccgagc cgttcacggc caagcccgtc gcggtggtcg
     6601 gcgaccggat ggtggcggcg cacttcaccg gcatggagac gttgcagcgc accgtagagg
     6661 tgctcggccg cgcgctgctg ttcaccccgg agctgcgcgg cgtcgaccgg ctggcggaga
     6721 aggtcgtcgc cgtcctcggc gcgctcggcg cccggttcgc cacggccatg cggctcgacg
     6781 cgttccgcca gcaggaggag atcaagagcg cgctgctgca ggcgaagcag ggcgtcgaac
     6841 gggtgctcag ggtcagcgag gcgcggttcc gggaggtgtt cgactcgtcg gtgatgggca
     6901 tcgcgatcac cgagccggac ggcacggtcg tcgaggccaa cgaggcgatg aacgcgatcc
     6961 tgggcagtga gaggagcctg atcgggcggt cgctgccccg gcacttccac ccggacgacg
     7021 ccgaggtgct caccgcgtcc taccgctcgg tgcgcgaggg cgtggtcgac cggttccgcg
     7081 agcagcgcag gctcgtgcgg atcgacggcg agcccgcgtg ggtgtacctg gcggtgtcgg
     7141 tgctgcgcga cgccgacggc gagccggcgt tccacgtgac gatggtcgag gacgtcagcg
     7201 agctgcacct gatgcagaag aacctggatt cgctgctgct gcgcgacccg ctcaccgggc
     7261 tgtcgaaccg gcagcacttc gtcacccagc tggagaccgt gcacagccgt tccgagcacg
     7321 gcatcacgct ctaccacctg gacctcgact cgttctcgct gatcaacaac gggctgggcc
     7381 acgacaccgg cgaccggctg ctcaagcaga ccgcgtcgcg gctgcgggcg gtcgtggccg
     7441 accaggacgc gttcgtcgcg cggatcggcg gcgacgagtt cgccgtcgtc gtggacaact
     7501 cccccaccac ccccggtgtc cccacgatga tcgacaagat caacgacgag ctcgccgagc
     7561 cgacgttcgt cgacgaccgg ggcatcgccg tgaccgccac gatcggcgtg ctcgaccggc
     7621 cgtccccgga gtggacggtg gggcagctgc tgcgcgcggc gaacatgacg ctgaccctgg
     7681 cgaaggccaa gggcaagcgg cagtggctgc cctacgaccc gcacgaggac gcccggcagc
     7741 gcgcggccgc gcgggtcacc gcggccctgc ccggcgcgtt cgagaacggc gagctggagg
     7801 tcgacttcca ccccgtcgtc gggctcgccg accggaccgt cgtcggcgtg tccgccaggc
     7861 tgcgctgggg ttcgctcggc caccggcagt gcctcgcgat ggccgacgag accggcctgt
     7921 cgctcccggt cggccagtgg atgctgcggt acgccgccga gcgcgtggtg ctctggcgcg
     7981 aggccaccgg cgtcaccccg ctcccgctgc acgtggccct gagtcccatg cagtcgcgcg
     8041 acgaggacct ggtcggcgcc gtgaagcgca ccctcgacga gaccggctta cccgtcgggg
     8101 acctgcggat ctccttgcac accagggccg tgctcatcgg cggcagcgac gacaacgtgc
     8161 aggtgctgac cgactccggc atccccaccg ggctgaacga cttccacggc ggccaggacg
     8221 agctggccct gctcaccgaa ctgccgatcc actccctcac catcgccccc gccaccgtcc
     8281 gggcgctggc cgaccgcacc gcccgcaacc ccttggccca caacgccatg gcctccctcg
     8341 tggcggtcgt ccgccaggcg ggcgtgagcg tgaccgccgc cggtgtcacc accgacgccg
     8401 aggccgactg gtgggcgggc atcggcaccg acgccgccca gggcgacttc tacaccgcct
     8461 cccgcaccac cggccccctc gccgccctgt tccaggacag accctaggcg ggcacggtcg
     8521 tgaagaactc gtagctgtgc ccgtccgggt cggcgacgta gacccctcgt ccacccgcca
     8581 gccggttgat ccggcggtcc cagccgccgc cgggccccga cccgaaccgg acgtccacat
     8641 cggactccag cctcgccagc aggtggtcga aggtcgtgtc gtccaccagg aacccgaagt
     8701 gcccggccga gaacggcggc cgctcgtcga agtccagcgt caggtcgtcg ttgacccgca
     8761 ccggcgtgaa cggcccggcg ggctcaccga cctcgcggcc gaccagcccg gcgaagaacg
     8821 ccgccgacac gtccttgtcc gtggcgcgga cgatggtgtg gttgaggaca agagtcacgg
     8881 gacacctcca aagcatgcga tccgcatgca atatagatgc gatccgcata cgtccgctag
     8941 ggttcctcca tgccttcgaa cgacggtggg cccgccctct tccgcctcgt ccggttctgg
     9001 tcgcgccggt gggcgaaggg gtccgagggg gacgcgtcgc acgcgcagct ggtgctgacc
     9061 gtcgaggcgg tcgccgcgtc cggcaccgac ggctccgtcg gcgacgtcgc ccggctgctg
     9121 ggcctcgacc aatccggggc cagccgcatg gtcgcggcgg cggaggcggg cgggtacgtc
     9181 gaccgcgccc gcgcggcctc cgacgcccgt cgcagcgcgc tccgcctcac cccagggggc
     9241 cgcgccctcc tgcggtccgc gcgcggctgg cagcggagca cgttcgccga gctgaccgcc
     9301 acctggccgg aggaggaccg cgaccggttc gcggcctacc tccgacggct ggccgaccag
     9361 gtcggcgcct gactacaact gcttcaccgc cgccagcagc ttcgtcagcg agtccttcgc
     9421 gtccccgaac agcaacgtcg tcttcgcgtt gtacagcagc tcgttgtcga tccccgcgaa
     9481 ccccggccgc atcgaccgct tcatgaacac caccgcacgg gcccggtcca cgtcgaagat
     9541 cggcatgccg tagatggggc tggtcggctc gtcgcgcgcg ccggggttca ccacgtcgtt
     9601 cgccccgacg accagcgcga cgtccatgct cgtcatgccg gggttgacgt cgtcgagctc
     9661 cttgagctgc tcgtagggca cgtcggcctc ggccagcagg acgttcatgt ggcccggcat
     9721 gcggcccgcg accgggtgga tgccgtagtc gacggtgatg ccgcggccct cgaggagcgt
     9781 gacgagctcg cgggcggcgt gctgggcctg cgcgacggcc aggccgtaac cgggcacgac
     9841 gacgatggag tgcgcgtagc ccagcaggat ggcgacgtcc tcgacggtgc cggagcggac
     9901 cgtgcgctgc tcctcgccgc gcacctgcac ggcggtcgcg gtgaacgcgc cgaacaggat
     9961 gttggtcagc ggcctgccca tggcctgcgc catcatccgg gtcagcagcg tgccggacgc
    10021 gccgacgagc gtgcccgcga cgatcagcag ggtgttcgcc agcacgtacc cggaggcggc
    10081 gacggcgaga ccggtgaacg cgttgagcag cgagatcgcg atcggcacgt ccgcgccgcc
    10141 gaccggcagc acgaacgcga tcccgagcag cagcccggcg accgtgagcg cgacgagcag
    10201 cgcggtggac gacgtggcga gcacggccac ggccagcacg aggctgaccg ccacgacgcc
    10261 gatgctcagc acccgaccgg cgggcagcac caccgggcgg gtggtcatga tctcctggag
    10321 cttggcgaag gtgaccaggc tgcccgagaa gctgcccgag ccgatcagca cggtgagcac
    10381 ggtcgcgatc cggaacagca gcgggccgcc gtcgtggaac tccgcgagcg cgacgagcgc
    10441 ggcggccgcg ccgccgaccc cgttgaacag ggccaccatc tgcgggatgg cggtcatctt
    10501 caccgaccgc gcggcgggca ccgcgacgac cgcgccgagc gcgatggcga ccaggatcca
    10561 cagtccgttg tggacggcgc cctggacgaa agccgtgacc acggccagga ccatgcccgc
    10621 ggcgccgagc aggttgcccg cgcgggcgaa ccgcggcgtg ctcaacccct tgagcgccaa
    10681 caggaagcac agggcggcga cgaggtaggc cagctgcgcg ctcatcgctt gtgccccttg
    10741 aacatctcca gcatccggtc ggtcaccacg aacccgccga ccacgttgac cgtggccagg
    10801 aacaccgcga gcagccccag caccagctgc accgcgccct cggcggcgcc ggtgatcagg
    10861 atggcgccga ccaggatcac cccgtggatg gcgttggctc ccgacatcag cggcgtgtgc
    10921 aggatcgtgg acaccttcga gaccacctcg aaccccacga acgcggccag cacgaagatc
    10981 gtgagcaggt cgatcacagc agccccctgg tcggctcgtg ccgcacctcg cccgcgtgcg
    11041 tcaggcagca cccggcgagc acctcgtcgg tgaggtccgg ctcgacgaca ccgtcctcgg
    11101 tcatcatcat cagcaggttc gccacgttgc gggcgtagag cttgctggcg tggatcggca
    11161 tgccgctggg catgttccgg gcgccgtgca cgagcacgtc gccgacccag acctcctggc
    11221 ccgccaccga gcccgcgcag ttgccgccgg actccgcggc caggtccacc acgaccgaac
    11281 cgggcgccat cgccttgagc atgtcggtgg tcaccagcac cggtgccgcc cgaccgggga
    11341 tcgccgcggt cgtgatcacc acgtcggacg cggcgacccg ctcggcgatc agctcccgct
    11401 gccgctccag gaacgtctcg gactgctcgg ccgcgtacac cccctgctgc gtctccaacg
    11461 gcagctcgac gaaccgggcc cccaggctgc gcacctcctc cgcggcggcc gcccgcacgt
    11521 cgtaggcctc cacgacggca ccgagcctgc gcgcggtcgc gatggcctgc aaccccgcca
    11581 caccggcgcc gagcacgagg accttcgcgg gcggcacggt accggcggcg gtggtgaaca
    11641 tgggcaggaa ccgcggcagc cgttcggccg ccaccagaac cgcgcggtaa cccgccacca
    11701 gggcctgcga ggacaaggcg tccgcgccct gcgcacgggt gacccgcggg agcaggtcga
    11761 ggctgaacga ggtgaccccg cgctcggcca gcacccgcac gagctccagc tcgttgggcg
    11821 gggacaagaa gctgatcgtg atgtcgccgg gacgcaacct gcgcgcctgg gcgatctcca
    11881 gaggttggac ggacaggaca gcttcgacct cgccgaccgt gtcctgcgcg acgacctggg
    11941 caccagccgc ccggtacgcc gcgtcagcgg cgtacgcgtg cgtcccagcg cccgattgga
    12001 cgtccacgac aagacccgcg ccgaccagcg tgcgcaccgt atccgggacg caggccacgc
    12061 ggcgctcggc gggccgcgac tccgcgggaa tcccgactct cacacctcag caccctaggc
    12121 ttggtgagtg atctggacca cagagcggtt ttaacggtga tcgccgtacg gccgtacggc
    12181 tgagtgttaa cgggggttgg gccgggggtg caggttgctg gctgatggcg cttggctgtg
    12241 gctacccgtg cgaagtgcga gtgggagacc gcccgctggt gaggttcggt tttggccctc
    12301 ccgccctctg gcgaagccca gcccccggcg cgcgattgtc tcaatgcctg atcttgcttg
    12361 tcaagacggt gaagctgtct tgacaagcaa gatcaggcag gagggcgctg tggatcgggg
    12421 gcagagggga agtctggctt cgccagcatc aggcttcgcc tgactcaggc atcctcgctg
    12481 cgcgtcggac caggcatcgg actccgtccg acactgcatc ctcggctgcg ccgtcggacc
    12541 aggcatccgc gcttcgcggc ggacgaggca tcggctggcg ccgacgaggc cccaggcgct
    12601 ccgcgccgga tgcgcgctgg cgggcttcgc ccaacgttgt gttgtgctcg gcttcgccat
    12661 cggtctgccg gcgggtgagc tctcgccctg tgctcggctt cgtcagtgga tgactgggca
    12721 gactccggtg gtgccgttgg ggaagaagtt gggcacctgt tcctccttgt cgtagtagcg
    12781 gtggaagacc ggggtcaggg agccggacat gggggggacg atccaggtcc agtcggtggg
    12841 gcacttgcgg cctgcggctt cttccttctg gacgtgggtc aggaagcgct gggattcggt
    12901 gtggtggtcg gtgatggtga cgccggcctc ggcgaaggag tgcaggacgg cgcggttgag
    12961 ctcgacgagt gcgcggtcgc gccagagggt ctgctcgcag gaggtgtcca ggcccatcct
    13021 cttgccgagg taggggagca ggtcgtagcg gtcgttgtcg gcgaggttgc gggcgccgat
    13081 ctcggtgccc atgtaccagc cgttgaaggg ggcggccggg tagtcgatgc cgccgatgcg
    13141 catccgcatg ttgctgatga cgggcacggc gtgccagcgg aggccgagct tggcaagcca
    13201 tggcagttcc ggatggctca gcgggacctc gaggacggcg tccgggggga ggtcgaccat
    13261 gccggactcg ccgtccgagg tctcgaccag cacggggagg acgtcgaagg ggccgcgggt
    13321 gcgcgggggc tgccagccgc gggtgatcgc gaggtcggtg agctcgaggt tgcggcggtc
    13381 acccaggaca ccaccgtccg ggccgcggta ggccgcgtac cggatgagct gctcgttgcg
    13441 gacgcgagga ccggggtggc cgggttcgtc gggggcgaac acggtcatca cgggtcggat
    13501 cttgcccgcg ttggtggcga tccgcaggtg ctcgacgcac tcgtccgcca cctccttggg
    13561 gtcgtggaga tctcgcaggt cccgcacctt caggctgcgc cagtacagcc tgccgatgca
    13621 tcgcgcgctg ttgcgccagg caaccctggc gccgaaggtc aactcggttg tggtgtgccg
    13681 gtaggtgccg gtcgccgcga tctccgcgtg cacttcggcg agacggtcct ccaccgggcc
    13741 taggtcatgg ttttcctcgt ggtggagccg gatgaactcc tccgcctcgg cgatgtcgac
    13801 ctcggtggcc ggcacggcca ccgcgttctc gacaagcgac ggggggaggg gcatcacgtc
    13861 atccggacac gttgggacgg gggccatggc gggtcaccgt aattgcacat cggtggacgg
    13921 tgcaccgccg tgacggtcac cggcaagcgc gagccaggta cggccggtgg gcacgcaaag
    13981 tgcttgatcc gtcaatcggg tgatcagagc tgcgattacg ggtggtgctg caatcgttac
    14041 ccgccagaag cctgccggtt acccatgacg aagatcacac caaaagacaa cccggtccgg
    14101 tgacacggag ggcttccgga acgatgcccc cgtgttcacc ttccgttcac caagcggaat
    14161 actcgccgga tcatgatcga gttgagcgca gccctctacc tgttcatcac cggcatcgcc
    14221 cacgagaccc ccgactgggt gcacacgatc gcggacatcg gcaccgacgc gggcctgctg
    14281 gtgttcgtcg ccctgttcgc gtggaatgcc tggcgcaaca ggggaacgcc cgagtaccgg
    14341 ctcgcgctgg tggcacccct ggcggtgatc ggcgcctacc tggtgagcga ggtcgcgaag
    14401 accttcatcc aggaggagcg cccgtgccgc gcggtcgccg gggcggtgtt catcgccgag
    14461 tgcccggccg tcggcgactg gtcgttcccc agcaaccacg cgaccatcgc ggcggcctgc
    14521 gcggcggtgc tggcgaccgt ctggggtcgg gtcgccctgc tggtgttccc attggcgatg
    14581 cttatggcgt tctcgcgggt cttcgtgggt gtgcactacc cgcacgacgt cgccgcgggg
    14641 ttcctggtgg gcgccacggt cggcgcgctg ctggccctgc tggcggtcag actggtcggt
    14701 ccggcgaagg cggcgccgcg agtgccggtg gggtccaggc gctgaacctg gtcatcccgg
    14761 acagcgcgac ccccgtcggc accgacctca tcagcgcgtt ccgcacggcg acggcggccg
    14821 ggtggcgcag cccgtgcccg acccggccca tgagccgcga cgccctggcc accgaccggg
    14881 tgcgcggccc gcgttcccgg tcgtagcggg tcagcgcggc cgccacggtg tcggcgtccg
    14941 cgcacgcggc ggcgaggacg acgccgtcct cgatcgcctg gcacgcgccc tggccgagga
    15001 acggggtcat ggcgtgcgcg gagtcgccga gcagcgcgac gcgcccgtgc acgtaggtgg
    15061 acggcggcgc ggccagctcg tggacgtcgt ggcgcagcac cgacccgccc ggtgtgcccg
    15121 ccagcagggc ggggatcggg tcggcccagt cgccgcacag ccgcacgacc tcggccagct
    15181 cgtccggcgc gcgcaggccg ggcgcggaca gggtcgcggc gtaccagtag acccggcccg
    15241 cggccagcgg caggacgccg aactcggtgc cgggcccgag gtactggccg atctccaggt
    15301 caccggtgtg gtcggtgacc gcccgccagg ccgtggtgcc ggagtagacc ggcgcgggca
    15361 cctccggcca cagccgcgac cggacccggc tgccgatgcc gtcggccgcg accaccaggt
    15421 ccgcctccag ctcgacgggg tcgccgtcgg cgaggtagcg caccctcggg acgacctcga
    15481 cgacgtcggc cgaggtgacc aggcactccg cgggcagcgc cgagcgcagc acccggtgca
    15541 ggtcggcccg gtggatcgcg acgagcctgc ccgcgcgttc cagctccgcg gcgtccaggt
    15601 gccctagagc gcgtcctcga tggtcgcgga caccgccggg gagccggggc gtgccgtcgt
    15661 ggcgcacggc ctcgcccagg cccagggcgt ccagcgcgcg cagggcgttg ggcatcacgc
    15721 cgatgcccgc ccccacctcg ccgaactccg gcgcccgttc gagcacggtc acccgccagc
    15781 cgacccggtg cagcgcgacc gccgccgtca gcccgcccag tcccccgccg accaccaccg
    15841 ccgtgccccg catgctgacc ccctcgtttc tacaggtgta gagacagcga tactacagct
    15901 gtagaaggaa ggggcaaggc gttgagcgac cgcaccgacc tgctcgccga cgcggccatc
    15961 cacgtcgtcg cgacccacgg gatgcgcggg ctgacccacc gcgcggtcga cgcgcgcgcc
    16021 ggggtgccgc agggctcgac gtcggcgtac ttccggaccc gcaaggcgct cgtcgaaggg
    16081 ctcgtccggc ggctcgcgga cgtcgagacg gccgacatcg acgcgacccg gctgacctct
    16141 cagacctccg acggcccgcc cgacctcgac cgggtcgccg cgggcgtggc cgcgctgctg
    16201 gaccactggc tcggcgccgg gcgcgaccgc agcctggcca ggttcgcctg cctgctggag
    16261 gccacccacc accccgagct gcgcacgatc ctcgcctacg gcgaccggcc gcgggcccag
    16321 gcgcgcgagc tcgtggcggc gctcggctcg accgacccgg aacgggacgg ccacgacctg
    16381 gtgtcgttcg tcgacggcct gctgttctac cggctggcgg gcggcggggc ggcccacgcg
    16441 cccgcgcccg gcacgcccga gagcctcgcc gagctgcacc gcgcggcgct ggccgcgctc
    16501 accggcgtgc tcgcccggcg gtcccccgcc cggtaatccg gtggcgggcc cccgacggct
    16561 tccctatcgt cgcggccatg gtcccgccgt tcttcgtgtt ctacctctga tctcggccgc
    16621 gacgcggcgg gcggtcgctc gccgcgtcct cgacgtgccc gagagcgctc gccgtccggc
    16681 ttgagcgcca gagctcgcgg agcgcccccg tcgtggtcgc gcgctcccgt tccgaagagg
    16741 tgaccccagt gcgcgcacga ctcgtgcaac cccgccatgc ccacctgagg accgaggacc
    16801 tgggcaaggg cttcgaagcc cgccccgtcc tgtccggcgt ccacctgacc gcgtcgaccg
    16861 ggcagcggct cggcgtgatc ggcgagaacg gccgcggcaa gtccaccctg ctgcgcctgc
    16921 tcgcgggcga cctcgaaccg gacgcgggca ccgtgacccg gcacggctcg gtcgccacgg
    16981 ccgcgcagga gctcccgttc accgccgacg acaccgtcgg cacgctgctc gaccacgccc
    17041 tcgcgccggc ccgtgccgcg gtcgccgagg tggacggcgc cgcggccgcg ctcgccgacg
    17101 ccgagccggg tgccgacgac cggtacgcgg tggcgctcgc cgaggccgag cggctggagg
    17161 cgtgggacgc cgagcgccgg gccgacctgg cgctcgcggc cctggacgcg cccgccgacc
    17221 gggcgctgcg gctggccgag ctgtccgtgg ggcagcgcta ccgggtgcgg ctggcctgcg
    17281 tgctggccga gcgcgcggac atcctgctgc tcgacgagcc gaccaaccac ctggacgcct
    17341 ccggcatggc gtacctgacc gcgcggctgc gcgagcacca gggcgtggtc gtgctggtca
    17401 gccacgaccg ggcgctgctg gacgaggtgt gcacggccct gctcgacctg gacccgaacg
    17461 ccgagggcga ggtggtgctg cacggcggcg gctactccgc ctaccggtcg gccaaggccg
    17521 cggagcgggc ccggtgggag cagcggtacg ccttggaggc gtccagggac gcggagctgc
    17581 gggagcaggt gtccgccgcc gaggcgcggc tggtgacgtc ctggcggccg cccaaggggg
    17641 ccggaaggca caagcgcgcg acgcgggcgc cgagccggat gcgcaccgtc gcccgccgcc
    17701 tggaggagct gaccgaccgc cgggtgccgg agccgcccgc cccgctgcgg ttcgcgagcc
    17761 ccgacctgga ggcgggtccg gacgaggtgc tgctcggcgc ctccggggtc accgtgcccg
    17821 gtcggctgcg gccgcacccg gacctcgcgg tggccgcggg cgggcggctg gtcgtgtccg
    17881 gcgcgaacgg gacgggcaag tcgacgctgc tgggcgtgct ggccgggcgg gtggtcccgg
    17941 cgtccggcgc ggtccaccgc ggcgggcgga cccggatcgg gctgctggcc caggagtcgg
    18001 acttcccgga cccgtcgctg agcccggtgc ggctggcggg cggcgacgcg gagccgttgc
    18061 gcggactggg cctgctggcc gacgtggacc tgacccggcc cgtgggcagg ctgtcgaccg
    18121 ggcagcgcag gaggctgtcg ctcgcactgc tgctcctgcg cgcgccgcac gtgctgctgc
    18181 tcgacgagcc gaccaaccac ctgtcgatcg cgctggtcga cgagctgacc gaggccctgc
    18241 tggtgaccgc cgcggccgtc gtcgtggcca cccacgaccg gcggctgcgg gccgacctgg
    18301 gcgactggcc ggagctggaa ctcatttgaa aacaatgttc ttcacagagt agtgaagctt
    18361 ctgtagcttc tgaagcaggt ccctacgcac tgggaggtgt gcaagttgac cggaacgatc
    18421 accgctgccc tgccgacgac gcgcgacaac gcgttcgacc cgcccgccga actgggggtg
    18481 ctccgcgagg agcggccgct gaaccggctc cagttccccg acgggcacgt gggctggctc
    18541 gtcacgaacc acgagctggt ccgcgagatc atggcggacc gccgcttcag ctcgcgcagc
    18601 gagctgcacc actccgtcat cacccgcgcc gacggcaagc cggtccgcag gcccgccgcg
    18661 acgcccggca tgttcatcgg gatggacgcg ccggaccaca cgaggtaccg caagctgctg
    18721 accggccagt tcaccgtgcg caggatgaac ctgctgtcgg cccgcatcga ggagatcgtc
    18781 caggagcacc tgaaggcgat gcgcgcgaac ggcacgtcgg gcgacctcgt ccaggcgttc
    18841 gcgctcccca tcccctcgct ggtgatctgc gagctgctgg gcgtccccta cgacgagcgg
    18901 cacgggttcc aggaggacac cgccacggcg ctgcggctgg agacctccgc ggacgaggcc
    18961 atcgcggcgt tcgagcggat caaggacttc atccgcgacc tcgtgcggcg caagcgcgcc
    19021 aaccccggcg acgacatgct cagcggcctg atcgcgagcg gtgagcacct cgacgacgag
    19081 gagatcaccg gcatgggcgt cctgctgctg gtggccgggc acgagacgac cgccaacatg
    19141 ctcggcctcg gcacgctggc cctgctcggc aaccccgacc agctcgccgc gctgaaggcg
    19201 gacccgtcgc tggtcgacaa caccgtcgag gagctgctgc ggtacctgtc gatcatccag
    19261 ttcggcacga cccgcacggc gctggaggac gtggagatcg ccggcgaggt gatcaaggag
    19321 ggcgacacgc tgtcgctctc gctggccgcc gccaaccgcg acccgcagcg gttcgaccac
    19381 cccgaccggc tggacgtcca ccgctcggcg aacgggcaca tgagcttcgg ccacggcgtg
    19441 caccagtgcc tcggccagca gctcgcccgc atcgagatgc ggatcgccta ctcggcgctg
    19501 ttcgccgagt tcccggacct gcgcctggcg gtgcccgccg acgaggtgcc gctgcgcacc
    19561 gacatggcca tctacggtgt ccactcgctg ccggtggagt ggtcatgagg atcgaggccg
    19621 acgtgaacaa gtgctgcggg tccggcatgt gcgccctgac cgacccggag ctgttcgacc
    19681 agagcgagga ggacggcacg gtcctcgtcc tcgtcagcga gcccggtccc gagcaccacg
    19741 ccgcggcccg cgaagccgcc gcgctgtgcc ccgcgggagc catcaccgtg cacgggtgac
    19801 cgcaccccgc gaccccgccg cccaccccgg cggggtcgcg ggaaccccgc tgaccacgcc
    19861 ttccgcccgg acaggggccc tgctaggggc cgtttagggg ccgccagggg tgtccggggc
    19921 acaaacccgt cattagcttt cgatccagtg atctgtggcg gaagacgacg tgcgggtttc
    19981 tgtgaaaagg gtggcgctga atgtccaacg agcagaagct tcgcgattac ctcaggcggg
    20041 tgaccgcgga cctgcacagc acccgccacc gtttgcagga ggtcgagggg acgggccagg
    20101 agcccatcgc gatcgtggcg atgggctgcc gcttcgcggg cggcatcacc tcccccgagg
    20161 agctctggga cttcgtcgtg gacggcgggg acgccgtcgc gcccttcccc accgaccgcg
    20221 gctgggacct ggaggcgctc taccaccccg atcccgacca ccagggcacg tcgtacgtca
    20281 tggagggcgc cttcgtcgac ggcgtcgccg agttcgaccc cggcttcttc ggcatctcgc
    20341 cgcgcgaggc gatcacgatg gacccgcagc agcgcctgct gctggagacc acgtggcaca
    20401 cgttcgagcg cgcgggcatc gacccgcacg cgttgcgcgg cagccggacc ggggtgttca
    20461 cctccaccaa cggccaggac tacatcacca agctgcaggg cgagctgccc gacgggctgg
    20521 agggccacgt cggcaccggc accgcggcga gcatgatctc cgggcgcatc tcctacacgt
    20581 tcggcctcga aggccccgcc gtcaccgtgg acaccgcgtg ctcgggctcg ctggtcacgt
    20641 tgcacctcgc ggtgcaggcg ctgcgcaacg gcgagtgcga cctggcgctg gccggcggcg
    20701 cgacgatcat ggtgacaccg ggcgcgttca tcgacttcag ccgcgcgcgc ggcctctcgt
    20761 gggactcccg ctgcaagtcg ttcgcggcgg gcgcggacgg cacgagctgg ggcgacggcg
    20821 tcggtctggt gctggtggaa cggctgtccg acgcccggcg caacggccac gaggtgctgg
    20881 ccgtcgtgcg cggcatcgcg gtgaaccagg acggcgcctc gaacggcctg accgcgccga
    20941 acggcccgtc gcagcagcgg gtgatcaagc aagccctggc cgacgcgcgg ctgtccgcgg
    21001 tggacgtcga cgtgatcgag gcgcacggca ccggcacgaa gctcggcgac ccgatcgagg
    21061 cgcaggcgct gatcgcggcg tacggacctg agcgcgagac ccctctgctg ctcggttcgg
    21121 tgaagtccaa catcggccac acgcaggccg ccgccggtgt cgccgccgtc atcaagaccg
    21181 tgatggcgct gcgccacggc gtggtgccca agacgctgca cgtggacgcg ccgtcgccgc
    21241 agatcgactg gagctccggc accgcggagc tggtgaccga gaccagggcg tggccggaga
    21301 ccgggcacgt ccgccgggcc ggcgtgtcgt ccttcggcta cagcggcacg aacgcccacg
    21361 cgatcctcga acaggcaccg gaggaccccc tcgacgtcga gggcgacgag cccgcggccg
    21421 ccccccgcga gctgccggtc gtgccggtgc tgctgtccgg gaagaccgag caggcggtgc
    21481 gggcgcaggc cgccgcgctg ctggagtcgt tgcccggcaa cgacttggcg gacctcgggt
    21541 tctccaccgc gacgacgcgg gcgcacctcg accaccgggc tgtgctcgtg gccgacgacc
    21601 gcgacggcct gctggccgcg ttgggggcgc tcgccgacgg caccgcaccg gtcgcgggcg
    21661 aggccgtgga gggccgcacc gccgtgctgt tcaccggcca gggcagccag cgggtcgcca
    21721 tggggcagca gctgtacagc gctttcccgg tgtacgccga ggcgttcgac gccgtgtgcg
    21781 accggttcga cccgcggctg cgcgaggctt tcgccgacca ggacctgctg aaccggacgg
    21841 agttcaccca gcccgcgttg ttcgcggtgg aggtggcgtt gtaccggttg gtggagtcgt
    21901 ggggtgtgcg gccggacttc ctg
//
