LOCUS       NZ_PVTF01000010        21041 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Umezawaea tangerina strain DSM 44720 Ga0180964_110, whole genome
            shotgun sequence.
ACCESSION   NZ_PVTF01000010
VERSION     NZ_PVTF01000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Umezawaea tangerina
  ORGANISM  Umezawaea tangerina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Umezawaea.
REFERENCE   1  (bases 1 to 410031)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 410031)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Expected Final Version            :: No
            Genome Coverage                   :: 86.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003002815.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:47:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,483
            CDSs (total)                      :: 9,418
            Genes (coding)                    :: 9,322
            CDSs (with protein)               :: 9,322
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 20 of 97
            Pseudo Genes (incomplete)         :: 83 of 97
            Pseudo Genes (internal stop)      :: 2 of 97
            Pseudo Genes (multiple problems)  :: 8 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 168412
            Orig. end                         :: 189453
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVTF01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21041
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21041
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21041
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11041](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11041)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            279..1052
                     /locus_tag="CLV43_RS31325"
                     /old_locus_tag="CLV43_110144"
     CDS             279..1052
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020665951.1"
                     /locus_tag="CLV43_RS31325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110144"
                     /product="ABC transporter permease"
                     /protein_id="WP_342749822.1"
                     /transl_table=11
                     /translation="MSASGVVGRPVGRERGPVGLGRVFVVELVDDLRGIVREPTALFFS
                     IVMPVGFFVLFVSMFGRQNSGMLATFGTFGVLAVTLMNPGMGVAKDRERGWLRAKQVSA
                     VPVWVTLAAKVAASFPYAVGVLVAMAAAAAATGSLSATPWQMARLVVVLLLGAFPFALL
                     GLAVGFRASTNAAAAILNALLMPSAIFSGLWMPLAFLPAFFSHVAPFLPPYHLAQLALA
                     QLQPGDGVLGHALVLVAMTVVSAGLAGLSYRSARP"
     gene            1049..2125
                     /locus_tag="CLV43_RS31330"
                     /old_locus_tag="CLV43_110145"
     CDS             1049..2125
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007024992.1"
                     /locus_tag="CLV43_RS31330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110145"
                     /product="sensor histidine kinase"
                     /protein_id="WP_106191642.1"
                     /transl_table=11
                     /translation="MTTSRLRVWTWVHLVYLGLPAFQPIFDPTADAGDWALVAFIVVAF
                     LPMYAMSLLRPWQARWWLTVPATVLGVLAVHFNAGAAVLFVYAAACAGLTETRRTALRW
                     FGFLTTLTLVFGVLSATPMPYRLWNVVPPVLFIWVIGLVQIAEAARARANTELRMENAR
                     IEHLATVSERERIARDLHDLLGHSLTAVVMRAQLVEQLVAVDPERARAEVREIERTARD
                     ALSEVRATVSGWRQASLEAELDAARGALASTGVDLHVRRDPDLALLGSTEHALALAVRE
                     AITNVARHADARTCQVGIHAVDGELRVVVADDGVGGGADGNGLSGMRERIAALGGRVHR
                     TATEGTTVTIAVPLRVAT"
     gene            2122..2724
                     /locus_tag="CLV43_RS31335"
                     /old_locus_tag="CLV43_110146"
     CDS             2122..2724
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034878.1"
                     /locus_tag="CLV43_RS31335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110146"
                     /product="response regulator transcription factor"
                     /protein_id="WP_106191643.1"
                     /transl_table=11
                     /translation="MIRVVLAEDQGMVLGAFAALLDLQPDIEVVAAVSDGDAALTAVTE
                     HRPDVLLTDIEMPGRSGLDVAAELRRRDDPTRVLIVTTFARGGYLRRAMDAGVLGYVLK
                     DAPIAQLADALREVHAGHRVIAPELAVAAWDSADPLTDRERELLREVLDGASNTDIAHR
                     LHLAEGTVRNYLSTAMAKLNARNRTEAATTARDHGWL"
     gene            complement(3135..4094)
                     /locus_tag="CLV43_RS31345"
                     /old_locus_tag="CLV43_110147"
     CDS             complement(3135..4094)
                     /GO_function="GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020423450.1"
                     /locus_tag="CLV43_RS31345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110147"
                     /product="magnesium transporter CorA family protein"
                     /protein_id="WP_106191645.1"
                     /transl_table=11
                     /translation="MASTRLYRKGRLEASDFDLDQVSDHLQDPDAVVWVDFHSPSQEDL
                     ATIAQELGLHALAIEDALAKHERPKFDQYDGHSFLTAKAVRFDDGVLAPTEVSAFITDR
                     ALVTVRDEFDFADVLKRWDEPGDLSGVGVGFLLHGLLDSIVDGHLAAAQKLDDEIEDLE
                     DVLFEERPDHKGMQRRALRLRKNLVMLRRVELPMADVVGALLRTDDTIVTDELRPYFQD
                     VNDHVLRVTDWTESLREMTTTLRETQLTAQGNVMNMIMKKVTSWAAIIAVPTAITGFYG
                     QNLPYPGFERAWGFWVSTAAIVALSGVLYATFKKRDWL"
     gene            complement(4104..5462)
                     /locus_tag="CLV43_RS31350"
                     /old_locus_tag="CLV43_110148"
     CDS             complement(4104..5462)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077730.1"
                     /locus_tag="CLV43_RS31350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110148"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_106191647.1"
                     /transl_table=11
                     /translation="MEQVVVVGGGPVGLWLAAELGLGGVPVTVLEARTERDPHSKALTI
                     HPRTLEVLAFRGVVDRFLAEGLRIPNGHFGGLDDRMDFRVLDTDFPFTLALPQVRTEEL
                     LEEHARTRGARILRGHQVTGLRQDADSVALRVTGPDGPYEVEAAYVVGCDGTRSAVREA
                     AGIAFPGTPDTTWGWLADVVLDSPPPSLLSVSGPNGGLMVVPLPGGAHRFVGGSDHTER
                     PGELTLEEVRATVTAITGTDFGMRDPHWLSRFGNATRQAERYRRGRVLVAGDAAHMHFP
                     AGGVGLNVGVQDATNLGWKLAATALGTAPHGLLDSYHDERHPVGADLLLSTRAQTALMN
                     AATPEVLALRTLLSGLIATVPEFSRTLAERLSGLAVAYDRGAHPLVGTRAPDLRVGDTT
                     LFTLLRTGKHVPLDFTDEPAKHDGWEDVRGAVVRPDGHVAWASGDTAPDPATH"
     gene            5515..6144
                     /locus_tag="CLV43_RS31355"
                     /old_locus_tag="CLV43_110149"
     CDS             5515..6144
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020422026.1"
                     /locus_tag="CLV43_RS31355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110149"
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="WP_106191649.1"
                     /transl_table=11
                     /translation="MTKKSATGLDPDTVVRAALELLDDKGADAVSVRGVADRLGVRMNT
                     VLWHAKTKARLLELMADAIVAGATVEDLPGPWRDRVRELAHRYRRALLARRDGARIVAG
                     TYAAEPATLRFADTMVGALLDAGFPARQAVWVCWTIVYFVLGLTQEEQAVPEALGEDFA
                     RVLASGEYPSLALAREHFEDGSFDERFDHGLSLVLRGLAPQGEDGV"
     gene            6141..6542
                     /locus_tag="CLV43_RS31360"
                     /old_locus_tag="CLV43_110150"
     CDS             6141..6542
                     /GO_process="GO:0030638 - polyketide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019013.4"
                     /locus_tag="CLV43_RS31360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110150"
                     /product="ester cyclase"
                     /protein_id="WP_106191650.1"
                     /sec_met_domain="PF07366 (E-value: 2.2e-29, bitscore: 96.3,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEDLETRYRAYLAVLNERRLDDLAHHLCDELTYNGEPMTRQRYQ
                     EQRAADIAAIPDLFFDAHVVVAAGDRVACRLVFDCTPVGEFLGFAPTGGRFVFAEHVFY
                     RYEEGRIAEVTSLIDRAAIAEQIRSGAHG"
     gene            complement(6549..7316)
                     /locus_tag="CLV43_RS31365"
                     /old_locus_tag="CLV43_110151"
     CDS             complement(6549..7316)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1208: pirin
                     domain-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013674294.1"
                     /locus_tag="CLV43_RS31365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110151"
                     /product="pirin-like bicupin family protein"
                     /protein_id="WP_106191652.1"
                     /transl_table=11
                     /translation="MSQSTLQPQVDVRRSAERDATKISWLDSKHSFSFGQKYDPANTHH
                     GLLLVNNDDVVRPGAGFETHPHRDMEIVTWVLQGSLVHQDSTGHSGIIYPGLAQRMSAG
                     RGIMHSEKNDSWRLEGAAHQDPVRFIQMWVVPDENRITPGYEQLEIDNDLLGGGLVPVA
                     SGMDVHEGAAAIRIKNKYAALHAARLQAGQSVELPEAPFLHLFVARGSVTLEGAGALAE
                     GDAVRFTATGGQRVTATEPAEVLVWEMHATIAG"
     gene            complement(7416..8300)
                     /locus_tag="CLV43_RS31370"
                     /old_locus_tag="CLV43_110152"
     CDS             complement(7416..8300)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (20-114). E-value:
                     2.2e-12. Score: 39.5. Matches aSDomain:
                     nrpspksdomains_CLV43_RS31370_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104000.1"
                     /locus_tag="CLV43_RS31370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110152"
                     /product="SRPBCC family protein"
                     /protein_id="WP_106191654.1"
                     /transl_table=11
                     /translation="MTTPRAALDTLDGHPVLRFRRTLPHSPAKVWRAITQPSELAAWFP
                     AAVELDLRPGARIRFTFPSEAPVDEGGTGEVLEVDPPKVFSFRWNSDVLRFELVPTATG
                     CTLHFTQTLGDRLSAGRNAYGWDTCLAALDAHLDGREPAPPGDHLAPMEAYIREFGLDE
                     GTLEDGVVRFTRDLVWKPAADVWALLTENTEPATGDAPPPRATNPHVPTGPLTEVAAPH
                     VLAYGPVHWEVTQDADLGTRVTLTHVLDATADPALVLAAWHVHLELFFAAVLGEVRCPW
                     PEDRTEELRKHYA"
     aSDomain        complement(7959..8240)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLV43_RS31370_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.20E-12"
                     /label="CLV43_RS31370_Polyketide_cyc2.1"
                     /locus_tag="CLV43_RS31370"
                     /protein_end="114"
                     /protein_start="20"
                     /score="39.5"
                     /tool="antismash"
                     /translation="RTLPHSPAKVWRAITQPSELAAWFPAAVELDLRPGARIRFTFPSE
                     APVDEGGTGEVLEVDPPKVFSFRWNSDVLRFELVPTATGCTLHFTQTLG"
     misc_feature    8296..8311
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(<8390..8689)
                     /locus_tag="CLV43_RS31375"
                     /old_locus_tag="CLV43_110153"
                     /pseudo=""
     CDS             complement(<8390..8689)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020423046.1"
                     /locus_tag="CLV43_RS31375"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110153"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /pseudo=""
                     /transl_table=11
                     /translation="MASTFAILADPSRREILDLLRTGERPVGDLVDRLTLTQPTVSKHL
                     KVLREAGLVDVRQDAQRRWYRLRPQPLAEIDAWLAPYRRMWEHSLDALERHLDTM"
     misc_feature    complement(8670..8684)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            8904..9161
                     /locus_tag="CLV43_RS31380"
                     /old_locus_tag="CLV43_110154"
     CDS             8904..9161
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020674244.1"
                     /locus_tag="CLV43_RS31380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110154"
                     /product="hypothetical protein"
                     /protein_id="WP_245887126.1"
                     /transl_table=11
                     /translation="MTAVVRSSEVVKMCTVPDVMGMVHQDAQDAMQASGLYVLLERDAT
                     GQGRLLINDRNWTTTGQMSGPGEVVDCGTTVTLSAKKVGE"
     gene            complement(10001..11041)
                     /locus_tag="CLV43_RS31385"
                     /old_locus_tag="CLV43_110155"
     CDS             complement(10001..11041)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103444.1"
                     /locus_tag="CLV43_RS31385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110155"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_106191657.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.3e-63, bitscore:
                     207.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVEDKQAVRSAHEVLSWSRFGVEPALRGAVERMPESMRVISGY
                     HFGWRDEHGQPTGGNSGKAIRPALTLLAAEAVGSVAAAAMSAAVAVELVHNFSLLHDDV
                     MDRDTTRRHRPTAWSVFGVNSAILAGDSMLALALDVLADSGHPSAQQGMRMISASVQGL
                     LDGQAADMAFEERGDVDLLECVKMAEGKTGALLGCACAIGALFGGGSTQQVQELRGFGE
                     ALGLAFQFADDLLGIWGDPSVTGKPVFSDLRNRKKSLPVVAALNSGTEAGRELDTLYHS
                     DHPLSPSDLSRAADLVDLAGGRAWSQARADDLLTRARTHLTNATPRPRAAAELDALAEL
                     ATHRDH"
     gene            complement(11055..12452)
                     /locus_tag="CLV43_RS31390"
                     /old_locus_tag="CLV43_110156"
     CDS             complement(11055..12452)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944751.1"
                     /locus_tag="CLV43_RS31390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110156"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_245887127.1"
                     /transl_table=11
                     /translation="MTVTDPGLEEAAAPSSLSTRAARNLASTTKSAPQMQGITPRWLLR
                     SLPWVEASGGAYRVNRRLSYAVGDGRVTFTNTGTAVRVIPQELRELPALRDFDDDAVLS
                     ALADRFQQREFAPGEVIVRAGRAADEVVLIAHGKVSATGVGHYGEETSLGVLADGDHFG
                     DEVLTGTVDEWPFTVRAVTPTIVLVLPWREVQRLNGQADALRAHIQGFVARSGKPSNKA
                     GEASIEMSSGHEGEVELPGTFVDYELSPREYELSVAQTLLRVHTRVADLYNHPMDQVQQ
                     QVRLTVEALRERQEHDLLNNPEFGLLHNADLKQRLHTRTGPVTPDDMDDLLSRRRKTAF
                     FLAHPRTIAAFGRQLNQRGLYPTPMDYNGTKVNTWRGVPILPSDKIPISSTGTSSVLAM
                     RVGEQENGVIGLHQTGLPDEYEPGLSVRFTGIDDKAVLSYLVSAYYSAAVLVPDALGVL
                     ENVEIDR"
     gene            complement(12493..13911)
                     /locus_tag="CLV43_RS31395"
                     /old_locus_tag="CLV43_110157"
     CDS             complement(12493..13911)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225101.1"
                     /locus_tag="CLV43_RS31395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110157"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_106191660.1"
                     /transl_table=11
                     /translation="MTVTDNPSSDVDSGRAQSSLATAAARNLATTTKSVPQMQGISSRW
                     LLKVLPWVQAAGGAYRVNRRLSYAVGDGRVTFTNTGAEIRVIPQELCELPLLRGYDDEA
                     VLTALSLKFVQREYAPGDLIVESGQRADTVFLIAHGKVNKIGVGEFGDQTALGVLADGD
                     HFGGEVLAGPQGEWEFTVKAVTPVTVLTLDWRSFEEMNGAAGGLREHIQHARARGENDK
                     RDESGEASIEMSSGHEGEVELPGTFVDYELSPREYELSVAQTVLRVHSRVADLYNQPMD
                     QVEQQLRLTIEALRERQEHELVNNREFGLLANADLGQRIHTRSGPPTPDDMDDLLATVW
                     KEPSYFLAHPRTIAAFGRECSKLGLYPASTDLGGHQVPSWRGVPILPCNKIAISQTRTS
                     SVMLMRVGEQNQGVVGLHQTGLPDEYQPGLSVRFMGIDEKAVISYLVSAYYSAAILVPD
                     ALGVLENVEIGREG"
     misc_feature    13985..14005
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.72"
                     /tool="antismash"
     misc_feature    14227..14241
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.24"
                     /tool="antismash"
     misc_feature    complement(14233..14245)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            complement(14289..15260)
                     /locus_tag="CLV43_RS31400"
                     /old_locus_tag="CLV43_110158"
     CDS             complement(14289..15260)
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012782834.1"
                     /locus_tag="CLV43_RS31400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110158"
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_106191662.1"
                     /transl_table=11
                     /translation="MKRAAIGLLTVLLTASLAACGSSSTPEAGGTSSGAGSAFPVTVDT
                     MFGQVEVEKAPTRVVALGWSDAETALALGVQPVGASDWLAFGGEGVGPWAKGLYEKAPT
                     ILGTQELSFEAVAALQPDLILNTRSNLDAKTNETLSKIAPTIAAPKDVIPYGTTWRQQM
                     ELVSKALGKPDKGTELIATVEKEFKDAATFSGKTAVVGTYFGNQYGAYVPGDGRVDFME
                     ELGFGTKKEIDSLAKGTFYVEISTEQLGLLDADLTVVFPIGTDAGVLRSDQVLNNIPSA
                     KAGHLVILDDKALSDAFSSGSTLGVSYAIKNAVPLFTAALRK"
     misc_feature    complement(15283..15301)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 28.73"
                     /tool="antismash"
     misc_feature    complement(15287..15304)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.06"
                     /tool="antismash"
     gene            15432..15935
                     /locus_tag="CLV43_RS31405"
                     /old_locus_tag="CLV43_110159"
     CDS             15432..15935
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017987522.1"
                     /locus_tag="CLV43_RS31405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110159"
                     /product="general stress protein"
                     /protein_id="WP_106191663.1"
                     /transl_table=11
                     /translation="MTAFMQSPSTVNIPTLPEGWPIASYSTYQEAQRAVDHLADSAFPV
                     QGITIVGVEPMLVERVAGRLTWGKVLGSAAASGAWLGLFVGLLLSLFTPGAGFAPIAIG
                     LVGGIAFGLATSAARYAATRGQRDFISTSQVVARRYDVLSVPANAQRGRDMLATLAMKG
                     PQVA"
     gene            15957..16817
                     /locus_tag="CLV43_RS31410"
                     /old_locus_tag="CLV43_110160"
     CDS             15957..16817
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010310468.1"
                     /locus_tag="CLV43_RS31410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110160"
                     /product="NAD(+)/NADH kinase"
                     /protein_id="WP_106191665.1"
                     /transl_table=11
                     /translation="MTEIGAVGLVLHPRRDCAQVIGTMVDWARSRDIKLFGVESEVERA
                     RGAVSSIGAEDLAGRVDLLVSLGGDGTMLRAMRLGIPDRTPVLGVNLGKLGFLAEIDPP
                     ELTDALCAIDEHRFTTEPRSGLRAVTGDKDAIAFNDVALVRVPGNGMTAVRLHVEGHPF
                     VSYSADAVVVATPTGSTAYSFSAGGPIISPRAEGLLITPVAPHSTFNRAVFLSGGEKLA
                     LEITGSEVGVEADGQLIGYVGAGTVIDIEVLPAAAQVVRLGRTTFYQRAQRKFGLSGFT
                     SQGEV"
     gene            complement(16864..17565)
                     /locus_tag="CLV43_RS31415"
                     /old_locus_tag="CLV43_110161"
     CDS             complement(16864..17565)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005163094.1"
                     /locus_tag="CLV43_RS31415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110161"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_342749823.1"
                     /transl_table=11
                     /translation="MWSTSQVAELAGTTLKTVRHYHRIGLLEEPDRKANGYKQYRVPHL
                     VRLLRIRRLVDLGVPLATIAGMEVSDENAERALRELDAELAADVERKQRMREELARVLR
                     HRALADLPPGFAADAGAAEGERSLLLLFSRVLNPAATAALRELHALPRLPIDAEFDALP
                     ADADPAVRQDLAERLAPVARRQREDFPALLDPTPHGDTTAMSVAARGLVEVYNPAQVDV
                     LRRLDALLQGR"
     gene            complement(17639..19114)
                     /locus_tag="CLV43_RS31420"
                     /old_locus_tag="CLV43_110162"
     CDS             complement(17639..19114)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (82-457). E-value:
                     6.3e-24. Score: 76.9. Matches aSDomain:
                     nrpspksdomains_CLV43_RS31420_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020665055.1"
                     /locus_tag="CLV43_RS31420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110162"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_106191666.1"
                     /sec_met_domain="PF00561 (E-value: 2.3e-28, bitscore: 93.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRTALPILAALVVATCAPASTATPGAPANTLVWGGCPGDAAVPG
                     LECATVEVPLDYRDPGGRKIGIAISRLAAADPRKRRGVLLTNSGGPGSPGLVYPAVLKL
                     YRLPPSVQDAYDVIGMDPRGVGYSSPVTCGLEPEQATLTANIPEYALTPADVAERAERM
                     AETAGRCGSSATASVLPHITTANTARDVDRVRQALGERKISYLGISYGTYLGAVYATLF
                     PERTDRVVLDSALGPGGPDVEASRGFGRGFEDRFPDFAEFVAARPEYGLGTTPAEVEAT
                     YSELAAELDAAPRPDGFDGRRFRHVTLEKLYLDAWLPELAEIWRAVRGGQPLPPPSAGP
                     PATDPVDNPVASQLAVMCNDSDWPESVAAYQRDVEADRVRHPKFGAAAANIRPCAFWPW
                     EPTEPPVRITGKGPANVLVVQNLRDPSTPLAGARELRNAFGERARMVTADQGGHLAYLY
                     LGNKCLNDTTTDFLATGRLPHDDVACAAERGGR"
     aSDomain        complement(17744..18868)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLV43_RS31420_Abhydrolase_1.1"
                     /evalue="6.30E-24"
                     /label="CLV43_RS31420_Abhydrolase_1.1"
                     /locus_tag="CLV43_RS31420"
                     /protein_end="457"
                     /protein_start="82"
                     /score="76.9"
                     /tool="antismash"
                     /translation="VLLTNSGGPGSPGLVYPAVLKLYRLPPSVQDAYDVIGMDPRGVGY
                     SSPVTCGLEPEQATLTANIPEYALTPADVAERAERMAETAGRCGSSATASVLPHITTAN
                     TARDVDRVRQALGERKISYLGISYGTYLGAVYATLFPERTDRVVLDSALGPGGPDVEAS
                     RGFGRGFEDRFPDFAEFVAARPEYGLGTTPAEVEATYSELAAELDAAPRPDGFDGRRFR
                     HVTLEKLYLDAWLPELAEIWRAVRGGQPLPPPSAGPPATDPVDNPVASQLAVMCNDSDW
                     PESVAAYQRDVEADRVRHPKFGAAAANIRPCAFWPWEPTEPPVRITGKGPANVLVVQNL
                     RDPSTPLAGARELRNAFGERARMVTADQGGHLAYL"
     gene            complement(19279..20493)
                     /locus_tag="CLV43_RS31425"
                     /old_locus_tag="CLV43_110163"
     CDS             complement(19279..20493)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020415951.1"
                     /locus_tag="CLV43_RS31425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110163"
                     /product="cytochrome P450"
                     /protein_id="WP_106191668.1"
                     /sec_met_domain="p450 (E-value: 2.1e-13, bitscore: 44.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPSEQVVTITAEFKADAPARYAELRELGPVHRSRFSTGLEGWLV
                     VGHDAALDALVHPALVKNSAPSRDKLAAANYTNDRPGVGLGGNMLVSDPPDHTRLRKLV
                     AGAFSPARTRALAPRVQRIADDLLDRLVPKGEADLVEAFTAPLPVAVISELLGVPEADR
                     ADFRRWSSLTLGAPSDPQREAALNLNRYLADLIAAKRRSPADDLLSALVAVRDEDDGRL
                     SEVELVGTAVLLVVAGHETTVNLLGNAVVALLRDPAQADLLRGRPELVPGAVEEFLRYD
                     SSVEHATPRFAAEDLVIAGTPVARGDVVMVALSSASRDMPVPDHGDPAELDVTRNGVRH
                     LSFGHGIHYCLGAPLARLEAATALSTLLRRIPDLRAAAPLDELEWVPSGIMRGPLALPV
                     RFTPR"
     misc_feature    20550..20568
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.51"
                     /tool="antismash"
     gene            complement(20575..20835)
                     /locus_tag="CLV43_RS31430"
                     /old_locus_tag="CLV43_110164"
     CDS             complement(20575..20835)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640404.1"
                     /locus_tag="CLV43_RS31430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_110164"
                     /product="hypothetical protein"
                     /protein_id="WP_106191950.1"
                     /transl_table=11
                     /translation="MTTTTPSHRDLALLRAVAAGRAQITCSCEPDLFIDGVACCDQVAA
                     GRLARSGLVEARVPAALGQRVPARLTALGARVLGEGLGLSA"
ORIGIN
        1 cgaggccgtg ttgagggtgc tgctggcggc ggatccgggg ttgggggacc tgcgggtgga
       61 acaggcgggg ctggaggagg ccgtggtgag catcggggcg ggggtgtgag ggtgcgctcc
      121 gcggaccgac cggtgcgcac tcgtccgtcc acaccagacc ggtcggtctg cccgacttcc
      181 ggttccggtg gtggaaccgg ggaaccgttg ggcggtctgg tgacgtccta ctcgcgcgcg
      241 cggcgtgcgg gacatgtgac ctgcagagga gctgtggcgt gagcgcgtcg ggagttgtcg
      301 ggcggccggt cggccgggag cgtggaccgg tcggtctggg gcgggtcttc gtcgtggagc
      361 tcgtggacga tctgaggggt atcgtccgcg agcccacggc gttgttcttc tcgatcgtga
      421 tgccggtggg gttcttcgtg ctgttcgtgt cgatgttcgg gcggcagaac agcgggatgc
      481 tggcgacctt cgggacgttc ggcgtgctgg cggtgacgct gatgaacccc ggcatggggg
      541 tggcgaagga ccgggagcgc gggtggctgc gggcgaagca ggtgtcggcg gtgccggtgt
      601 gggtgacgtt ggcggccaag gtggcggcgt cgttcccgta cgcggtgggg gtgctggtgg
      661 cgatggcggc ggccgcggcg gcgacggggt cgttgagcgc gacgccgtgg cagatggcgc
      721 ggctggtcgt ggtgctgctg ctgggcgcgt tcccgttcgc gctgctcggg ctggcggtgg
      781 ggttccgggc gagcacgaac gcggcggcgg cgatcctgaa cgcgctgctg atgccgtcgg
      841 cgatcttctc ggggctgtgg atgccgctgg ccttcctgcc cgcgttcttc tcgcacgtcg
      901 cgccgttcct gccgccctac cacctggccc agctcgcgct ggcgcagctc cagccgggtg
      961 acggggtgct cgggcacgcg ctggtgctgg tcgccatgac ggtcgtgagc gcgggactgg
     1021 ccggtctgtc ctatcgttcc gctcgaccat gacgacatcc cgcctgcgcg tgtggacctg
     1081 ggtgcacctc gtgtacctgg gtctgcccgc cttccagccg atcttcgacc cgaccgccga
     1141 cgcgggggac tgggcgctgg tcgcgttcat cgtggtggcg ttcctgccga tgtacgcgat
     1201 gtcgctgctg cgcccgtggc aggcgcggtg gtggctgacg gtgcccgcga cggtgctcgg
     1261 cgtgctcgcc gtgcacttca acgcgggtgc ggcggtcctg ttcgtctacg cggcggcgtg
     1321 cgcggggctg accgagacgc ggcggacggc gttgaggtgg ttcgggttcc tcacgacgct
     1381 gaccctggtg ttcggggtgc tctcggcgac cccgatgccc taccggctgt ggaacgtcgt
     1441 cccgccggtg ctgttcatct gggtgatcgg gctggtgcag atcgcggagg ccgcccgcgc
     1501 ccgcgccaac accgagctgc gcatggagaa cgcgcggatc gagcacctgg ccacggtgtc
     1561 cgagcgggag cggatcgcgc gggacctgca cgacctgctg gggcactcgc tcaccgccgt
     1621 ggtgatgcgg gcgcagctgg tggaacaact ggtggccgtg gaccccgagc gggcgcgggc
     1681 cgaggtgcgc gagatcgagc gcaccgcgcg ggacgccctc agcgaggtcc gcgccaccgt
     1741 gagcggctgg cggcaggcca gcctggaggc cgagttggac gccgcccgag gggcgctggc
     1801 gagcaccggg gtcgacctgc acgtgcgccg cgaccccgac ctcgccctgc tgggctccac
     1861 cgaacacgcc ctcgccctcg ccgtccggga ggcgatcacc aacgtcgccc gccacgcgga
     1921 cgcccgcacg tgccaggtcg gcatccacgc cgtcgacggc gagctgcggg tcgtggtggc
     1981 ggacgacggc gtcggcggcg gagccgacgg caacggcctg tccggcatgc gggagcgcat
     2041 cgccgctctg ggcggccgcg tccaccgcac cgccaccgag ggcaccaccg tcaccatcgc
     2101 cgtccccttg cgggtggcga cgtgatccgg gtcgtcctcg ccgaggacca gggcatggtc
     2161 ctcggcgcct tcgccgccct cctcgacctc caaccggaca tcgaggtcgt cgcggccgtc
     2221 tccgacggcg acgcggccct caccgccgtc accgaacacc gccccgacgt cctgctcacc
     2281 gacatcgaga tgcccggccg ctccggcctg gacgtcgccg cggagctccg cagacgcgac
     2341 gaccccaccc gagtcctcat cgtcaccacc ttcgcccgcg gcggctacct ccgccgcgcc
     2401 atggacgcgg gcgtcctggg ctacgtcctc aaggacgccc ccatcgccca actggccgac
     2461 gccctccgcg aggtccacgc cggccaccgc gtcatcgccc ccgaactcgc cgtcgccgcc
     2521 tgggactccg ccgacccgct caccgaccgc gaacgcgagc tcctgcgcga agtcctcgac
     2581 ggcgcctcca acaccgacat cgcccaccgc ctccacctcg ccgaaggcac cgtccgcaac
     2641 tacctctcca ccgccatggc caagctcaac gcccgcaacc gaaccgaagc cgccaccacc
     2701 gcccgcgacc acggctggct gtaagttcac aatggactcc gcgacccggc cacccaacaa
     2761 cgctggaacc aaagacaagt cacccaacga cactggcggc agcacacaag tcacccagcg
     2821 acgctggaac caaagggcaa gtcgcccaac aacgctggaa gcagcacaca agcccccagc
     2881 gacgctggaa gcgagcatgc tcgtccgctc gtgcggtcgg cttgacttgg ggtttttggg
     2941 cttacaatga gtcggcgggc aggctctgcc acctgccctt tttcgcccga cgaagcccaa
     3001 aaaaggggcc ccaagtcaag ccgaccgcac ctgggtccgc tgtagcgaca cccccggagc
     3061 cccccgcagc gacaccccca gagaccacgg cccccacagc gccccccgac accgcccaac
     3121 cctccacaat agacctacaa ccagtccctc ttcttgaacg tcgcgtacaa cacccccgac
     3181 agcgccacta tcgccgccgt cgacacccaa aacccccaag ccctctcgaa ccccggatag
     3241 ggcaggttct gcccgtagaa ccccgtgatc gccgtgggca ccgcgatgat cgccgcccag
     3301 ctcgtcacct tcttcatgat catgttcatc acgttgccct gggccgtcag ctgcgtctcc
     3361 cgcagcgtcg tcgtcatctc ccgcaacgac tccgtccagt ccgtcacccg cagcacgtgg
     3421 tcgttgacgt cctggaagta cggcctcagc tcgtcggtca cgatggtgtc gtcggtccgc
     3481 agcaacgccc ccaccacgtc cgccatcggc agctccaccc gccgcagcat caccaggttc
     3541 ttgcgcagcc gcaacgcccg ccgctgcatc cccttgtggt cggggcgttc ctcgaacagc
     3601 acgtcctcga ggtcctcgat ctcgtcgtcg agcttctgcg cggcggccag gtgcccgtcg
     3661 acgatcgagt ccagcagccc gtgcagcagg aagccgaccc cgacgccgga caggtcgccc
     3721 ggttcgtccc accgcttcag cacgtccgcg aagtcgaact cgtcccggac cgtcaccagc
     3781 gcgcggtcgg tgatgaacgc ggacacctcg gtcggggcca ggaccccgtc gtcgaaccgg
     3841 acggctttcg cggtcaggaa ggagtgcccg tcgtactggt cgaacttcgg ccgctcgtgc
     3901 ttggccagcg cgtcctcgat ggcgagcgcg tgcagtccca gctcctgcgc gatcgtggcc
     3961 aggtcctcct ggctcggcga gtggaagtcc acccacacca ccgcgtccgg gtcctggagg
     4021 tggtcggaca cctggtccag gtcgaagtcg gacgcctcca acctgccctt gcggtagagc
     4081 cgcgtgctcg ccatgcctga aggctagtgg gtggccggat ccggggccgt gtcgccgctc
     4141 gcccacgcca cgtggccgtc ggggcggacc accgcgccgc ggacgtcctc ccagccgtcg
     4201 tgcttggcgg gctcgtcggt gaagtccagc gggacgtgct tcccggtgcg cagcagggtg
     4261 aacagggtgg tgtcgccgac ccggaggtcg ggcgcgcggg tgccgaccag ggggtgcgcg
     4321 ccgcggtcgt aggcgacggc gaggccggac aggcgttcgg cgagggtgcg ggagaactcc
     4381 ggcacggtgg cgatgagccc gctgagcagc gtgcgcagcg ccagcacctc cggggtggcc
     4441 gcgttcatca gcgcggtctg cgcgcgggtg ctgagcagca ggtccgcgcc gaccgggtgg
     4501 cgttcgtcgt ggtagctgtc cagcagcccg tggggcgcgg tgcccagcgc ggtcgcggcg
     4561 agcttccagc cgaggttcgt ggcgtcctgc acgccgacgt tgaggccgac cccgcccgcc
     4621 gggaagtgca tgtgcgcggc gtcgcccgcg accagcaccc ggccccggcg gtaccgctcg
     4681 gcctgccggg tggcgttgcc gaaccgggac agccagtgcg ggtcgcgcat gccgaagtcg
     4741 gtgccggtga tggcggtgac cgtggcgcgc acctcctcca gggtcagctc gccggggcgc
     4801 tcggtgtggt cggaaccgcc gacgaaccgg tgcgcaccgc cgggcagcgg caccaccatc
     4861 aggccgccgt tgggcccgga gaccgacagc agcgacggcg gcggggagtc cagcacgacg
     4921 tcggcgagcc atccccacgt cgtgtccggc gtgccgggga aggcgatgcc cgcggcctcg
     4981 cggaccgcgc tgcgggttcc gtcgcagccg acgacgtagg cggcctcgac ctcgtagggc
     5041 ccgtcggggc cggtgacccg gagcgccacc gagtcggcgt cctggcgcag gccggtcacc
     5101 tggtgcccgc gcaggatccg cgcgccccgc gtgcgcgcgt gctcctccag cagctcctcg
     5161 gtgcggacct gggggagtgc cagcgtgaac gggaagtccg tgtccagcac gcggaagtcc
     5221 atccggtcgt ccaggccgcc gaagtggccg ttggggatgc gcagcccctc ggccaggaac
     5281 cggtccacga caccgcggaa cgccagcacc tccagcgttc gcgggtggat cgtcagcgcc
     5341 ttcgagtgcg ggtcccgctc ggtgcgggcc tccaggacgg tgaccggcac cccgcccagc
     5401 cccagctcgg cggccaacca cagtccgacg ggcccgccgc cgacgaccac tacctgctcc
     5461 acggaatcct ccttggtcac tgaccaacaa ctggtgaggc cgtacactag gtcagtgacc
     5521 aagaagtccg caaccggcct ggacccggac accgtcgtgc gcgccgcgct ggagctgctg
     5581 gacgacaagg gggccgacgc ggtgtctgtc cgcggcgtcg cggaccggct cggcgtccgg
     5641 atgaacacgg tgctgtggca cgcgaagacc aaggcgcgcc tgctggagct gatggccgac
     5701 gcgatcgtcg cgggcgcgac cgtggaggac ctgccgggac cgtggcgcga ccgggtccgc
     5761 gaactggccc accgctaccg ccgcgcactg ctggcgcggc gggacggggc ccggatcgtg
     5821 gccgggacgt acgccgccga acccgccacg ctccggttcg ccgacaccat ggtcggcgcg
     5881 ctgctcgacg cgggattccc ggcgcgccaa gcggtctggg tgtgctggac gatcgtctac
     5941 ttcgtactcg ggctcaccca ggaggagcag gcggtgcccg aggcgctcgg cgaggacttc
     6001 gcccgcgtcc tcgcctccgg cgagtacccg tcactggcgc tggcccgcga gcacttcgag
     6061 gacggctcgt tcgacgagcg cttcgaccac gggctttccc ttgtgctgcg cgggttggcg
     6121 ccccaggggg aggatggggt gtgaccgaag acctggaaac ccgttaccgc gcttacctcg
     6181 ccgtcctcaa cgagcgtcgt ctcgacgacc tcgcgcacca cctgtgcgac gagctgacct
     6241 acaacggcga accgatgacc cggcagcgct accaagaaca gcgggccgcc gacatcgccg
     6301 cgatcccgga cctcttcttc gacgcgcacg tcgtcgtcgc cgcgggcgac cgggtggcgt
     6361 gccgcctggt gttcgactgc acgccggtgg gcgagttcct cggcttcgcg cccaccggcg
     6421 ggcggttcgt gttcgcggaa cacgtcttct accgctacga ggaagggcgc atcgccgagg
     6481 tgacctcgtt gatcgaccgc gcggccatcg cggagcagat ccggtccggc gcccacgggt
     6541 gaggccggtc agcccgcgat cgtcgcgtgc atctcccaca ccagcacctc ggcgggctcg
     6601 gtcgcggtca cccgctggcc gccggtcgcc gtgaaccgca ccgcgtcgcc ctcggcgagc
     6661 gcgcccgcgc cctccagggt cacggatccc cgtgccacga acaggtgcag gaacggcgcc
     6721 tcgggcagct cgaccgactg gcccgcctgc aacctggccg cgtgcagggc ggcgtacttg
     6781 ttcttgatgc ggatggccgc cgcgccctcg tggacgtcca tcccggacgc caccggcacg
     6841 agcccgccgc ccagcaggtc gttgtcgatc tccagctgct cgtagccggg cgtgatccgg
     6901 ttctcgtccg gcaccaccca catctggatg aacctgaccg ggtcctggtg ggccgcgcct
     6961 tccagccgcc acgagtcgtt cttctccgag tgcatgatcc cgcggcccgc gctcatccgc
     7021 tgcgccagac cggggtagat gatcccggag tgccccgtgg agtcctggtg caccaacgaa
     7081 ccctgcagca cccaggtcac gatctccatg tcccggtgcg gatgcgtctc gaaccccgcg
     7141 cccggccgca cgacgtcgtc gttgttcacc agcagcaggc cgtggtgggt gttggccggg
     7201 tcgtacttct ggccgaacga gaacgagtgc ttcgagtcca gccacgagat cttcgtggca
     7261 tcgcgctcgg ccgagcggcg cacgtccacc tgcggctgca aggtgctctg gctcataact
     7321 ggaccctctc ccgagttgat gtgtcaccta cgctcggtgg aacctagttg acggtgcaac
     7381 tattcccgga tcggggccgg atggccagtg gaggctcacg cgtagtgctt gcggagctcc
     7441 tcggtgcggt cctcgggcca cgggcagcgg acctcgccga ggacggcggc gaagaacagc
     7501 tccaggtgga cgtgccaggc ggcgagcacg agcgcggggt ccgcggtggc gtccaggacg
     7561 tgggtgaggg tgacgcgggt gcccaggtcg gcgtcctggg tgacctccca gtggacgggg
     7621 ccgtaggcga ggacgtgcgg ggcggcgacc tcggtgagcg gtccggtggg gacgtgcggg
     7681 ttggtggcgc gcggcggcgg ggcgtcgccg gtcgcgggct cggtgttctc ggtcagcagg
     7741 gcccacacgt cggcggcggg tttccagacg aggtcgcggg tgaagcggac gacaccgtcc
     7801 tccaacgtgc cctcgtcgag gccgaactcg cggatgtagg cctccatggg ggccaggtgg
     7861 tcgccgggcg gtgcgggttc gcggccgtcg aggtgcgcgt ccagcgcggc caggcaggtg
     7921 tcccagccgt aggcgttgcg gcccgcggag aggcggtcgc cgagggtctg ggtgaagtgg
     7981 agggtgcagc cggtggcggt ggggacgagc tcgaagcgca ggacgtcgga gttccaccgg
     8041 aaggagaaga ccttcggcgg gtcgacctcc aggacctcgc ccgtgccgcc ctcgtcgacc
     8101 ggggcctcgc tggggaacgt gaagcggatc ctggcgccgg ggcggaggtc gagctcgacg
     8161 gccgcaggga accaggccgc cagttcgctc ggctgggtga tggcgcgcca caccttggcg
     8221 ggggagtggg ggagggtgcg gcggaagcgg aggaccgggt ggccgtcgag ggtgtccagt
     8281 gcggctcgtg gggtggtcac ggggtggtcc cttctgcgct gtcgtcggcc gtggtgccgt
     8341 tgggtgtgct gtcgttgggt gtgctgtcgt cgggggtgct gtcttcgggc atggtgtcga
     8401 ggtggcgttc gagggcgtcg aggctgtgct cccacatgcg gcggtagggg gccagccagg
     8461 cgtcgatctc ggccaggggt tgggggcgga ggcggtacca gcggcgttgg gcgtcctggc
     8521 ggacgtcgac gaggcctgcc tcgcggagaa ccttcaggtg cttggagacc gtgggctggg
     8581 tgagggtgag gcggtcgacc aggtcgccca cggggcgttc gccggtccgc aggaggtcga
     8641 ggatctcgcg tctgctcggg tcggcgagga tcgcgaacgt tgatgccatg tgggcaatat
     8701 agccggattg acatactcaa gcaagtaacg cgggggcgtg cgaggctgac ataccgggca
     8761 ctcgtcggaa ccggaggctg tccaccatgg ttcgagcgct ggtcgtcgtg ttggccctgg
     8821 ttcttgggtc ctgtgcttcg ccggtggagg ggcctgttgt gccggtgcct tcgtcggttg
     8881 tgtcttcctc tgcgacttcc tccgtgacgg cggtggtgag gtcgtccgag gtggtgaaga
     8941 tgtgcacggt gcccgatgtg atggggatgg tgcaccagga cgcgcaggac gcgatgcagg
     9001 ccagtgggtt gtacgtgctg ctggagaggg atgcgacggg gcaggggcgg ttgttgatca
     9061 atgatcggaa ctggactacc accgggcaga tgtcggggcc tggggaggtt gtggactgtg
     9121 ggacgacggt gacgttgtcg gccaagaagg tgggggagta ggtggggggg tgtccggggg
     9181 tgtggtttgt ttggtgggcc ccggtctttg ctctcttgtc ttgtgagttt ggctcttgct
     9241 tgctggtgga gtctggtggc tggttcgctg gttgcgcggg gtctgacctc gggctctctt
     9301 gagctgtgag gctcggccct cggccctcgg ccctcggccc tcggcccttg cgcggtgcgc
     9361 agtccggcct tcggtccttc cgtggtgcga agtccggcgc ccggccctct cgccgcgcaa
     9421 gcccggcgcc cggccgtccc acttctggga agcctggccc ctggtctccc aatccctggt
     9481 gaagcccggc ccccggccct cccatccctg gtgaagcccg gcccccggcc ctcccatccc
     9541 tggtgaagcc cggcccccgg cgcgcgattg tctcaatgcc cgatcttgct tgtcaagatg
     9601 ataaagccat cttgacaagc aagatcgggc aggagggcgc tgtggatcgg gggcagaggg
     9661 gaagtctggc ttcgccagca tcgagcgccg ctcgactcaa gcatcaggct tcgcctgact
     9721 caggcatcgg acttcgtccg acaaggcccc aggcgctccg cgccggatgc gcgctggcgg
     9781 gcttcgcccc gttggctgtt gaggtcggct tcgccatcgg ttgggggcgg tgggtggggc
     9841 ggtgggtggg tgtttgcgct ttggtggatg tggattgggc ccaggacctt ccggtgcgaa
     9901 ggtcctgggc ccgtgggcgg cactcgtctg gcccggcgag tgtcgcggat tgggccgacc
     9961 cgctgggtgt cggtcggtga cgtggcagcg ggtcggggat ctagtggtcg cggtgggtgg
    10021 ccagttcggc gagggcgtcc agttccgcgg cggcgcgggg gcggggggtg gcgttggtga
    10081 ggtgggtgcg ggcgcgggtg aggaggtcgt cggcgcgggc ttggctccag gcgcggccgc
    10141 ctgccaggtc gaccaggtcg gcggcgcggc tgaggtcgga aggggagagg gggtggtcgg
    10201 agtggtagag ggtgtcgagt tcgcggcctg cctcggtgcc ggagttgagg gcggcgacga
    10261 ccgggaggga cttcttgcgg ttgcggaggt cggagaagac gggtttgccg gtgacggacg
    10321 ggtcgcccca gatgccgagg aggtcgtcgg cgaactggaa ggcgagaccg agggcctcgc
    10381 cgaagccgcg cagctcctgg acctgctggg tgctgccgcc gccgaagagg gcgccgatgg
    10441 cgcaggcgca gccgagcagg gcaccggtct tgccctcggc catcttcacg cactcgagca
    10501 ggtcgacgtc gccgcgctcc tcgaacgcca tgtccgcggc ctgcccgtcg agcaggccct
    10561 ggacggaggc gctgatcatc cgcatgccct gctgggcgga cgggtgaccg ctgtcggcga
    10621 ggacgtcgag cgccagcgcg agcatggagt cgcccgcgag gatggccgag ttgacgccga
    10681 acacgctcca cgccgtcggc cggtgcctgc gggtggtgtc gcggtccatc acgtcgtcgt
    10741 gcagcaacga gaagttgtgc acgagctcga cggcgaccgc ggcgctcatc gccgcggcgg
    10801 cgacgctgcc gacggcctcg gccgcgagca gcgtcagggc ggggcggatc gccttgccgc
    10861 tgttgccgcc ggtcggctgg ccgtgctcgt cgcgccagcc gaagtggtac ccggagatga
    10921 cgcgcatcga ctcgggcatc cgctcgaccg cgccgcgcag ggccggttcg acaccgaacc
    10981 tgctccacga cagcacctcg tgcgccgagc ggaccgcctg cttgtcctcg acatcggtca
    11041 tgacccgtcc tccctcagcg gtcgatctcg acgttctcga gcacgccgag cgcgtcggga
    11101 acgagcacgg ccgccgagta gtaggcgctg accaggtagg acaggacggc cttgtcgtcg
    11161 atgccggtga agcgcaccga caggccgggc tcgtactcgt cgggcagacc ggtctggtgc
    11221 aggccgatca cgccgttctc ctgctcgccg acccgcatcg cgaggacgga gctggtgccc
    11281 gtggaggaga tcgggatctt gtccgacggc aggatcggca cgccgcgcca cgtgttgacc
    11341 ttcgtgccgt tgtagtccat cggcgtcggg tacaggccgc gctggttgag ctggcggccg
    11401 aacgcggcga tcgtgcgcgg gtgcgccagg aagaacgcgg tcttgcggcg acggctgagc
    11461 aggtcgtcca tgtcgtccgg ggtgaccggc ccggtgcggg tgtgcagccg ctgcttgagg
    11521 tccgcgttgt gcagcagacc gaactccggg ttgttcagca ggtcgtgctc ctgccgttcc
    11581 cgcagcgcct ccacggtcag ccggacctgc tgctggacct ggtccatcgg gtggttgtag
    11641 aggtccgcga cgcgggtgtg cacccgcagc agggtctggg cgacgctgag ctcgtactcc
    11701 cgcggcgaca gctcgtagtc gacgaacgtg ccgggcagct ccacctcgcc ctcgtggccc
    11761 gaggacatct cgatcgacgc ctcgcccgcc ttgttgctcg gcttcccgga ccgcgcgacg
    11821 aacccctgga tgtgcgcccg cagcgcgtcg gcctggccgt tgagccgctg cacctcccgc
    11881 cacggcagga cgagcacgat ggtgggcgtg acggccctga ccgtgaacgg ccactcgtcg
    11941 acggtcccgg tgagcacctc gtcgccgaag tggtcgccgt cggccagcac gccgagcgag
    12001 gtctcctcgc cgtagtggcc gacaccggtc gcgctgacct tgccgtgcgc gatcagcacg
    12061 acctcgtcgg ccgcgcgacc ggcccgcacg atcacctcac cgggcgcgaa ctcccgctgc
    12121 tggaagcggt cggcgagcgc gctgagcacc gcgtcgtcgt cgaaatcgcg cagcgcgggc
    12181 agctcgcgca gctcctgggg gatcacccgc accgcggtac cggtgttggt gaaggtcacc
    12241 cggccgtcgc cgacggcgta gctgagcctg cggttcaccc ggtacgcgcc accgctcgcc
    12301 tcgacccacg gcagcgagcg cagcagccag cggggggtga tgccctgcat ctgcggcgcc
    12361 gacttggtgg tcgacgccag gttgcgcgcc gccctcgtgc tcaggctcga aggcgcggcg
    12421 gcctcttcga ggcccggatc tgtcaccgtc acgtgtcttc ccatctcctg acgtgcctac
    12481 cgacggacgg atctagccct cgcggccgat ctcgacgttc tccagcacgc cgagggcgtc
    12541 cggcacgagg atcgcggccg agtagtaggc gctgaccagg taggagatga cggccttctc
    12601 gtcgatgccc atgaaccgca cggacaggcc gggctggtac tcgtcgggca ggccggtctg
    12661 gtgcaggccg acgacgccct ggttctgctc gccgacgcgc atcagcatca ccgagctggt
    12721 ccgggtctgg ctgatggcga tcttgttgca cggcaggatc ggcaccccgc gccacgacgg
    12781 gacctggtgg ccgcccaggt cggtgctggc cgggtagagg ccgagcttgc tgcactcgcg
    12841 gccgaacgcg gcgatggtgc gggggtgcgc caggaagtag ctgggctcct tccacaccgt
    12901 ggcgagcagg tcgtccatgt cgtcgggggt gggcgggccg gaacgggtgt ggatgcgctg
    12961 gccgaggtcg gcgttggcga gcaggccgaa ctcgcggttg ttgaccagct cgtgctcctg
    13021 gcgctcgcgc agcgcctcga tggtcagccg cagctgctgc tcgacctggt ccatcggctg
    13081 gttgtagagg tccgcgacgc ggctgtgcac gcgcaggacc gtctgggcga cgctgagctc
    13141 gtactcgcgg ggggagagct cgtagtcgac gaacgtgccg ggcagctcca cctcgccctc
    13201 gtggccggag gacatctcga tcgacgcctc gccgctctcg tcgcgcttgt cgttctcgcc
    13261 gcgcgcacgg gcgtgctgga tgtgctcgcg caggccgccc gcggcgccgt tcatctcctc
    13321 gaacgagcgc cagtccaggg tcagcacggt gaccggggtg accgccttga cggtgaactc
    13381 ccactcgccc tgcggaccgg ccagcacctc gccgccgaag tggtcgccgt cggcgagcac
    13441 gccgagggcc gtctggtcgc cgaactcgcc gacgccgatc ttgttgacct tgccgtgcgc
    13501 gatcaggaac acggtgtcgg cccgctggcc ggactcgacg atcaggtcgc cgggcgcgta
    13561 ctcgcgctgc acgaacttca gcgagagcgc ggtgagcacc gcctcgtcgt cgtacccgcg
    13621 cagcagcggc agctcgcaca gctcctgggg gatcacccgg atctcggcgc cggtgttggt
    13681 gaaggtcacc cggccgtcgc cgaccgcgta gctcaggcgc cggttgaccc ggtaggcacc
    13741 gcccgccgcc tgcacccacg gcaggacctt gagcagccac cgcgaggaga tgccctgcat
    13801 ctgcggcacg gacttggtcg tcgtggccag gttcctggcc gccgccgtcg ccaagctcga
    13861 ttgcgcacga cccgaatcca cgtccgacga ggggttgtcc gtcacagtca cccgacatac
    13921 cgcctatccg cttgcgcgcc gctggtggcg cgtgagggaa ctcaattcac gaacaatgga
    13981 cttgttcgtg gcggtcagac gttaaccagc cggagcacgt ggggggaagc ggccaaaacg
    14041 gcgtcctccc atggtgtgac cagcggagat gttgggcact cgctgtgtac atgatggacg
    14101 gatcgcacta catcgggtga attttccagg tcggtacgac taagtcgcgc cgacctggaa
    14161 ttcgtaactc caatgctcta atgagaacca ctccatcgtg ggtctcaagt cgtggaaacc
    14221 gcgaacaaca tcgtgaaaat tgcaactcgg gagacgaagt tcccacggtc ggtcaaacgg
    14281 gtaagggctt acttccgcaa tgctgcggtg aacagcggga ccgcgttctt gatcgcgtag
    14341 gagacgccga gggtcgagcc gctggagaac gcgtccgaca gcgccttgtc gtcgaggatg
    14401 acgaggtgcc cggccttggc cgacgggatg ttgttgagca cctggtcgga ccgcagcacg
    14461 cccgcatcgg tgccgatcgg gaacacgacg gtcaggtcgg cgtccagcag gcccagctgc
    14521 tcggtggaga tctccacgta gaacgtgccc ttggccagcg agtcgatctc cttcttggtg
    14581 ccgaagccga gctcctccat gaagtccacc cggccgtcgc cgggcacgta ggcgccgtac
    14641 tggttgccga agtaggtgcc gaccacggcg gtcttgccgg agaacgtcgc cgcgtccttg
    14701 aactccttct cgacggtcgc gatgagctcc gtgcccttgt ccggcttgcc gagcgccttg
    14761 gagaccagct ccatctgctg gcgccaggtc gtgccgtagg ggatgacgtc cttcggcgcg
    14821 gcgatcgtcg gcgcgatctt ggacagcgtc tcgttggtct tcgcgtccag gttggaccgg
    14881 gtgttgagga tcaggtcggg ctgcagcgcc gccacggcct cgaagctcag ctcctgggtg
    14941 cccaggatgg tcggcgcctt ctcgtacagg cccttggccc acgggccgac gccctcgccg
    15001 ccgaaggcga gccagtcgct cgcgccgacc ggctgcacgc cgagcgcgag cgcggtctcc
    15061 gcgtccgacc agccgagcgc gaccacgcgg gtgggcgcct tctcgacctc gacctgcccg
    15121 aacatggtgt cgacggtcac cgggaacgcg gagcccgcac ccgaggacgt gccgcccgcc
    15181 tcgggggtcg aggagctgcc gcacgcggcc agcgatgcgg tcaggaggac tgtcaggagc
    15241 ccgatggcgg cgcgcttcat gttcacccgt tcgttctaga gtttaggtaa ccctaagcta
    15301 acacgctggt gggctgactg agaatcgcct gtgaagtccc ggtgaggggc acgattcgtc
    15361 ggtgcgccgt cgttgaaagg gacgtaagag cgaaaacgcc cccacggggg tcgttcacag
    15421 aggtgagtga gatgacagcg ttcatgcagt ccccgtcgac ggtgaacatc ccgacgctgc
    15481 ccgagggatg gccgatcgct tcgtacagca cctaccagga ggcccagcgc gcggtggacc
    15541 acctcgccga cagcgccttc cccgtgcagg gcatcacgat cgtcggcgtc gagccgatgc
    15601 tggtcgaacg ggtcgcgggc aggctgacct ggggcaaggt cctcggcagc gcggccgcct
    15661 ccggcgcgtg gctcggcctg ttcgtcggcc tgctgctcag cctgttcaca cccggcgccg
    15721 ggttcgcgcc gatcgcgatc ggcctcgtcg gcggcatcgc gttcgggctg gccacgtcgg
    15781 ccgcccgcta cgccgcgacc cgcgggcagc gcgacttcat ctcgaccagc caggtcgtcg
    15841 cccgccgcta cgacgtgctc agcgtccccg ccaacgccca gcgcggccgc gacatgctcg
    15901 cgaccctggc gatgaagggc ccgcaggtcg cctgacccgc ccgtagagtc cgggtcatga
    15961 cggagatcgg tgcggtgggc ctcgtcctgc acccgcgcag ggactgcgcc caggtgatcg
    16021 gcaccatggt cgactgggcg cggtcccgcg acatcaagct gttcggcgtc gagtcggagg
    16081 tggagcgcgc gaggggcgcg gtctcctcga tcggcgccga ggacctcgcc ggccgggtcg
    16141 acctgctggt cagcctcggc ggcgacggca ccatgctccg cgcgatgcgc ctgggcatcc
    16201 cggaccggac gccggtcctc ggcgtcaacc tcggcaagct cggcttcctc gccgagatcg
    16261 acccgccgga gctgaccgac gccctgtgcg cgatcgacga gcaccggttc accaccgagc
    16321 cccgctccgg cctgcgggcc gtgaccgggg acaaggacgc catcgccttc aacgacgtgg
    16381 ccctggtccg cgtccccggc aacggcatga cggcggtccg cctgcacgtc gagggccacc
    16441 cgttcgtcag ctactcggcc gacgccgtgg tcgtggccac cccgaccggc tcgaccgcgt
    16501 acagcttcag cgcaggcggg ccgatcatct cgccgcgcgc ggaggggctg ctgatcaccc
    16561 ccgtggcgcc gcactccacg ttcaaccgcg cggtgttcct gtccggcggg gagaagctgg
    16621 cgctggagat caccgggagc gaggtcgggg tggaggcgga cggccagctc atcgggtacg
    16681 tgggagccgg gacggtgatc gacatcgagg tgcttcccgc ggccgcgcag gtggtccgcc
    16741 tcgggcggac gacgttctac cagagggccc agcggaagtt cgggttgagc gggttcacca
    16801 gccagggcga ggtctgacga cggccgagca cccgatggtc gcggagcgga ccgaggaccg
    16861 cggctaccgg ccttgcagga gtgcgtccag ccgccgcagg acgtcgacct gggcggggtt
    16921 gtacacctcg accagcccac gggcggcgac cgacatcgcg gtcgtgtcgc cgtgcggggt
    16981 cgggtcgagc agcgccggga agtcctcgcg ctgacggcgg gcgacgggag cgaggcgctc
    17041 ggcgaggtcc tggcggacgg cggggtccgc gtccgcgggc agcgcgtcga actccgcgtc
    17101 gatcggcagg cgcggcaacg cgtggagctc ccgcagcgcc gccgtggccg cggggttcag
    17161 gacgcgggag aagagcagca ggagggaccg ttcgccctcc gccgccccgg cgtcggcggc
    17221 gaaccccggt ggcaggtcgg ccagggcccg gtgccgcagg acgcgggcca gctcctcgcg
    17281 catccgctgc ttgcgctcga cgtccgcggc cagctcggcg tccagctcgc gcagcgcccg
    17341 ttccgcgttc tcgtccgaga cctccatccc ggcgatcgtg gccagcggca cgcccaggtc
    17401 gacgagcctg cggatccgca ggagccggac caggtggggg acccggtact gcttgtagcc
    17461 gttcgccttc ctgtccggtt cctccagcaa cccgatccgg tggtagtgcc ggacggtctt
    17521 cagcgtcgtg cccgccagct cggccacctg gctcgtgctc cacaccaccg ccaccgccct
    17581 tcgcgccctt ccccgcaccg gcacggtagc gaccggcgcg gcgacgagga gcgggtcctc
    17641 acctcccgcc gcgttcggcc gcgcacgcga cgtcgtcgtg cggaagccgt ccggtggcga
    17701 ggaagtccgt cgtggtgtcg ttgaggcact tgttgcccag gtagaggtag gcgaggtggc
    17761 cgccctggtc ggcggtgacc atccgggcgc gctcgccgaa ggcgttgcgg agctcgcggg
    17821 cgcccgccag cggtgtggac gggtcgcgga ggttctgcac gacgagcacg ttcgccggac
    17881 ccttgccggt gatccgcacc gggggctcgg tgggctccca cggccagaac gcgcacggcc
    17941 ggatgttggc cgcggccgcg ccgaacttcg ggtggcggac gcggtcggcc tcgacgtcgc
    18001 gctggtaggc ggccaccgac tccggccagt cggagtcgtt gcacatcacc gcgagctggc
    18061 tcgcgacggg gttgtcgacc gggtcggtgg cgggaggtcc ggccgagggc ggcggcagcg
    18121 gctgtccacc gcggacggcc cgccagatct cggccagctc gggcagccag gcgtccaggt
    18181 agagcttctc gagcgtgacg tgccggaacc gcctgccgtc gaagccatcg ggcctcggtg
    18241 ccgcgtccag ctcggcggcc agctcggagt acgtcgcctc cacctccgcc ggtgtggtgc
    18301 ccaggccgta ctcgggacgc gcggcgacga actccgcgaa gtccgggaac ctgtcctcga
    18361 aacccctccc gaacccgcgc gaggcctcga cgtccggccc gccgggaccg agcgcgctgt
    18421 cgagcacgac cctgtcggtg cgttccggga acagggtggc gtagaccgcg ccgaggtagg
    18481 tgccgtagga gatgccgagg taggagatct tccgctcgcc cagcgcctgg cggacccggt
    18541 ccacgtcgcg cgcggtgttc gcggtggtga tgtggggcag caccgatgcc gtcgccgagg
    18601 atccgcaccg cccggcggtc tccgccatcc gctcggcgcg ttcggcgacg tcggccgggg
    18661 tcagcgcgta ctcggggatg ttcgcggtca gcgtggcctg ctccggctcc aggccgcagg
    18721 tgaccgggga gctgtacccg accccgcgcg ggtccatgcc gatcacgtcg taggcgtcct
    18781 ggacgctcgg cggcagccgg tagagcttca ggacggccgg gtagaccagt ccggggctgc
    18841 cgggcccacc ggagttggtc agcagcacgc cgcggcgctt ccgcggatcc gcggcggcca
    18901 gccgcgagat cgcgatgccg atcttccgac cgccggggtc ccggtagtcc agggggacct
    18961 cgaccgtcgc gcactccagg cccggcacgg cggcgtcgcc gggacatccg ccccacacca
    19021 gggtgttcgc cggggcgccc ggtgtcgccg tcgacgccgg ggcgcaggtc gccaccacca
    19081 gggcggcgag gatgggtagt gcggttctgc gcatgggtgc tcctcccgag gcggtccaca
    19141 gcggaccgga cgtgccccga ggggacaccg tgccctcggg gcacggtcaa gccgaaccgg
    19201 gggtcgtcac ccgagccgag ccgtggtgtg cgccggttct ccttgtcccc caacgcttcc
    19261 gtgcctgtcg gtgacgtcct accgcggggt gaagcggacc ggtagtgcga gcggaccgcg
    19321 catgatgccg ctgggtaccc actccagctc gtccaacggg gccgctgccc gcaggtcggg
    19381 gatgcggcgc agcagggtgg acagggcggt ggcggcctcc aggcgggcca agggggcgcc
    19441 gaggcagtag tggatgccgt ggccgaagga gaggtggcgg acgccgttgc gggtgacgtc
    19501 gagctcggcc gggtcgccgt ggtccgggac gggcatgtcg cggctggcgg aggagagggc
    19561 gaccatgacg acgtcgccgc gggcgacggg ggtgcccgcg atgacgaggt cctcggcggc
    19621 gaacctcggg gtggcgtgct cgacggagga gtcgtagcgg aggaactcct cgacggcacc
    19681 gggcacgagc tccgggcgcc cgcgcaggag gtcggcctgc gcggggtcgc ggagcagggc
    19741 gacgacggcg ttgccgagga ggttgacggt ggtctcgtgg ccggcgacga cgaggaggac
    19801 cgcggtgccg accagctcga cctcggacag cctgccgtcg tcctcgtcgc gcacggcgac
    19861 cagcgcggac agcaggtcgt cggcggggga gcggcgcttg gcggcgatca ggtcggcgag
    19921 gtagcggttg aggttcaggg cggcctcgcg ctgcgggtcg gagggggcgc ccagggtgag
    19981 ggagctccag cggcggaagt cggcgcggtc ggcctcgggg acgccgagca gctcggagat
    20041 cacggccacc ggcaggggag cggtgaacgc ctcgacgagg tcggcctcgc ccttcgggac
    20101 gagccggtcg agcaggtcgt cggcgatccg ctggacgcgc ggggcgagcg cgcgggtgcg
    20161 ggcggggctg aaggcgcccg cgacgagctt gcgcagccgg gtgtggtcgg gtgggtcgga
    20221 gacgagcatg ttgccgccga gaccgacgcc ggggcggtcg ttggtgtagt tggcggcggc
    20281 gagcttgtcc cgtgagggcg cggagttctt gaccagcgcg gggtgcacga gcgcgtcgag
    20341 ggcggcgtcg tggccgacga cgagccagcc ctccaggccg gtggagaacc gggagcggtg
    20401 caccggtccg agctcgcgca gctcggcgta gcgggcgggc gcgtcggcct tgaactccgc
    20461 cgtgatggtc acgacctgct ctgacgggtg catcggggtc ccctcgtcct gaacgggcga
    20521 aacctcgcca acgtacgcgg gggacgggga tgccgaacgg ccctgaaagg gtgatcaggc
    20581 gctgaggccg aggccctcgc cgagcacccg cgcgccgagc gcggtcagcc gggccgggac
    20641 gcgctggccg agcgcggcgg ggacgcgggc ctcgacgaga ccggagcggg ccagtcggcc
    20701 cgcggcgacc tggtcgcagc acgcgacgcc gtcgatgaac aggtcgggct cgcagctgca
    20761 cgtgatctgc gcacgtccgg cggccacggc gcgcaggagg gcgaggtccc ggtgggacgg
    20821 ggtggtggtg gtcatggcgg tcatctcgca tcgggtggtg ggtcgggcgc tgcaccgagg
    20881 agaacccgaa caggacccgc ctgaccaggg ctggaggccg gaagtggccg ggcgtacgcc
    20941 gtactcgtcc cgttcgtccc cgtggacgcc gtccacgggg acgaacgcgg ctcacacccg
    21001 ttcggcgggc gccccttcgg gttttccgtc ctcgcggtcg a
//
