LOCUS       NZ_PVTF01000009        12701 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Umezawaea tangerina strain DSM 44720 Ga0180964_109, whole genome
            shotgun sequence.
ACCESSION   NZ_PVTF01000009
VERSION     NZ_PVTF01000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Umezawaea tangerina
  ORGANISM  Umezawaea tangerina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Umezawaea.
REFERENCE   1  (bases 1 to 545808)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 545808)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Expected Final Version            :: No
            Genome Coverage                   :: 86.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003002815.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:47:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,483
            CDSs (total)                      :: 9,418
            Genes (coding)                    :: 9,322
            CDSs (with protein)               :: 9,322
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 20 of 97
            Pseudo Genes (incomplete)         :: 83 of 97
            Pseudo Genes (internal stop)      :: 2 of 97
            Pseudo Genes (multiple problems)  :: 8 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 148300
            Orig. end                         :: 161001
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVTF01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..12701
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="1"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12701
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12701
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7701](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7701)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    complement(133..147)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 20.84"
                     /tool="antismash"
     gene            complement(580..1533)
                     /locus_tag="CLV43_RS28820"
                     /old_locus_tag="CLV43_109132"
     CDS             complement(580..1533)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801793.1"
                     /locus_tag="CLV43_RS28820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_109132"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_106190858.1"
                     /transl_table=11
                     /translation="MSLAPAVDRPSPAEPTRSAPPWRSGGRGGYLVFLVPGALLLLAVV
                     VVPFAMNVGISLTRWSGVGDPVWIGLENYRKLFADSAFWASFRHNVGLVVAMAILPTIA
                     GLVVAAALFDFVGKRFGPRTASVLRACVYLPQVLPIAVAGIVWSWILAPKGGALNAFLD
                     AVGLGSLARDWLGDPDIALYSVMGVLVWIQLGYPVVIFMAGMQRVDPALLEAAELDGAS
                     WWGRFWHVTVPGIRPEVFVVMLTCSIAALKVFGPIYVLTRGGPAGATNVPSYFSFQNFF
                     ERTRVGYGAAVATVLTVLILLLTAFFLRVQNRREDS"
     gene            complement(1530..2813)
                     /locus_tag="CLV43_RS28825"
                     /old_locus_tag="CLV43_109133"
     CDS             complement(1530..2813)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801792.1"
                     /locus_tag="CLV43_RS28825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_109133"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_106190860.1"
                     /transl_table=11
                     /translation="MSTRLFAALVVALLAVSGCGGSSGDSDPKTLKLWHYEDPDSAMGK
                     AWAAAIAKFEEKHPGVKVAFEEKGFEQIQKTAPMVLNSNEAPDILEYNKGNATTGLLSR
                     QGLLADLSEQVSGRGWDKLMAPNLKTTSQYDERGVMGSGKWFGIPNYAEYVTVYYNKDM
                     FAARGVAVPKTFAEFTAAMDAFVAAGVTPLAVGGGEYPAQQVLYQLALSKADRAWVDRY
                     QRYTGDVDFHDAAWTYGATTFADWVAKKYISPEASGVKAEDMGLSFIQGKFPIMVSGSW
                     WQGRVAAGATGFQWGSFLWPGNKLNAGSSGNQWVVPAGSKNKDLAYDFIDITLSPEIQD
                     VLREAGGIPISPGGTPSTDPAAKALNDDFDTLAKNDGLAYYPDWPAPGYYDVMVSATQK
                     LITGTASPSQVLDELAKPYAENRANIGG"
     gene            complement(3093..4094)
                     /locus_tag="CLV43_RS28830"
                     /old_locus_tag="CLV43_109134"
     CDS             complement(3093..4094)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646747.1"
                     /locus_tag="CLV43_RS28830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_109134"
                     /product="proline racemase family protein"
                     /protein_id="WP_106190861.1"
                     /transl_table=11
                     /translation="MRSVRTLTAVDSHTEGMPTRVITGGVGVVPGDTMARRRLHFIENM
                     DHLRRFLVNEPRGHAAMSGAILQPPTRPDADWGVLYIEVSGCLPMCGHGTIGVVTVLVE
                     TGMVTVTEPETVVRLDTPAGLVEARVVVRDGRAESVTIENVPSFAIRQDAVVDVPGLGP
                     VRYDMAFGGNFYTILPIADLGIPFDRAEKDRMLAVGLDIMAAINATDRPVHPVDPAISG
                     CKHVQLTAPGEAGSDSRNAMVVHPGWFDRSPCGTGTSARLAQLHARGELELGVDHVNES
                     LLGTRFTGRLVRAERVGDVDAVVPTITGRAWITGMAQYLLDPTDPFPEGFVL"
     gene            complement(4096..5004)
                     /locus_tag="CLV43_RS28835"
                     /old_locus_tag="CLV43_109135"
     CDS             complement(4096..5004)
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010697118.1"
                     /locus_tag="CLV43_RS28835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_109135"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_106190863.1"
                     /transl_table=11
                     /translation="MTERLDGVIVATALPYIEDPSAPAGLRPDLDRYAEHCRWVVDNGC
                     RGVGPNGSLGEYSSLTDAERREVARTAIAAVGGDATVVVGVHAAGSHQARRWAELAAED
                     GADGVLCLPPTLYRANAREVVAHFTEVASVGLPVMVYNNPFDTKVDLTPELLTEIAAID
                     NVVAVKEFSGDVRRVLEIRERAPGLTVVAGADDVVVESLLMGATGWFAGFPNVFPAESA
                     RLYELATTGQVEEARELYEPLVAAFRWDSRTEFVQAIKRGMDQAGRFGGPCRPPRGPLS
                     AAQLDVLDADLRRAFDHLKGV"
     gene            complement(5001..6305)
                     /locus_tag="CLV43_RS28840"
                     /old_locus_tag="CLV43_109136"
     CDS             complement(5001..6305)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010697119.1"
                     /locus_tag="CLV43_RS28840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_109136"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_106190864.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.2e-25, bitscore:
                     85.3, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 6.2e-09, bitscore:
                     31.1, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVVVVGGGPAGLAAADAAVRAGAEVVLVDSEPWPGGQYHRGTPQ
                     RVDSRVRHLASSTVWAVEGLRLHVRRGPADSPHRTPHVLDADAVVLATGAHDRVVPFPG
                     WDLPGVYTAGAAQALAKGQGVAVGTRVVVSGTGPFLLPVAESLVRVGTQVLEVLEANAF
                     STWARYPHTLANVGKLGELARYAGVLGRHRIPVRTRAAVVAAHGDDRVTAVTVARLRPD
                     WSVVDGTRRRVAVDAVCVGHGFTPRLELAVGLGCRLVDGFVAVDATGATSVPGVYAAGE
                     VTGIGGADLAAAEGAVAGSAAARAPEPPIAAMRAVRRGRRFAMALVAAHPVGGGRHGWL
                     LADTVVCRCEEVTAHDLDVALDRGAADVRTLKLASRAGLGLCQGRVCGREVADLAAARL
                     GHPLPDADAFHRRPLATPLRLGELADTPLLPEEDL"
     gene            complement(6302..6559)
                     /locus_tag="CLV43_RS28845"
                     /old_locus_tag="CLV43_109137"
     CDS             complement(6302..6559)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020668271.1"
                     /locus_tag="CLV43_RS28845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_109137"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_106190866.1"
                     /sec_met_domain="Fer2_4 (E-value: 1.2e-24, bitscore: 81.2,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRITVDGEPHDVPPGRTIAGVLIAAGRSSWRTTRNGDRPRGVFCG
                     IGVCFDCLVVVNGVPDVRACLRYPADGDVVRTQHGAELPT"
     gene            complement(6556..7701)
                     /locus_tag="CLV43_RS28850"
                     /old_locus_tag="CLV43_109138"
     CDS             complement(6556..7701)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011873974.1"
                     /locus_tag="CLV43_RS28850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_109138"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_106190867.1"
                     /sec_met_domain="DAO (E-value: 4.8e-68, bitscore: 225.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYPDVVVVGSGVIGAACAEALSAAGAGVTVLDRGPLGAGTSAAG
                     EGNVLVSDKGPGPELDLALASLRRWPALLDELGVDVEWDAKGGLVVATGDEAAKALLGF
                     AADQRPEGVDARVVTPDEAHEREPHLTPAVVAAVHYPQDAQLQPVLVTKALLAAVRRRG
                     GTLRPGVRATGLRRRDDRVVAVRTAGGDVPCGIVVNACGPWSGEVSAAFGAPITVLPRR
                     GVILVTAALPPTVRHKVYDADYVGAVASGDADLQISTVVESTAGGTVLIGSSRQRVGFD
                     DSIRVEVLRALARRAVGLFPVLADVPVVRAYGGFRPYAPDHLPVVGADPRCAGLWHATG
                     HEGAGIGLAAATGRLLTELVTGAEPHLDPTPFRVDRPGVLG"
     misc_feature    7721..7732
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            complement(7763..8347)
                     /locus_tag="CLV43_RS28855"
                     /old_locus_tag="CLV43_109139"
     CDS             complement(7763..8347)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009945565.1"
                     /locus_tag="CLV43_RS28855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_109139"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_106190869.1"
                     /transl_table=11
                     /translation="MVREQAGQVLATNLRALREHGGLSLSELARRSGIAKGTLSQLESG
                     TGNPTIDTVFSLSNALGVPVSDLLTAPVDSEVVLVRAADLDVLSSNAVDLRMVRRLTIG
                     ETVVEVYDQRVRPGQTQYSAGHPGREHVLVTSGVLRVGPPAAPYELGPGDYVCFPAQTP
                     HTYETVGGPVESVLLLEHPDGAHPGRAAHGD"
     gene            complement(8403..9821)
                     /locus_tag="CLV43_RS28860"
                     /old_locus_tag="CLV43_109140"
     CDS             complement(8403..9821)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016698603.1"
                     /locus_tag="CLV43_RS28860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_109140"
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="WP_211304625.1"
                     /transl_table=11
                     /translation="MGRCVYTGIYEPGHPTADEDGFRGDVLALTRELGVALVRYPGGNF
                     VSAYRWEDGIGPVADRPARRDLAWRSVETNEVGIDEFARWARKADVEVMYAVNLGTRGV
                     QEALDVHEYVNHEGGTALSDLRRANGSEAPHGVALWCLGNELDGPWQTGHKTAHEYGRL
                     AAETARALRQAEPGLELVACGSSSSAMPTFGHWESTVLELTYDQVDHISCHAYYEVHDG
                     DVDSFLASAVDMDRFIDSVVATADAVGARLKSAKRIGVSFDEWNVWYQKRFHADPPVQW
                     RTAPRLIEDTYDVTDAVVVGSLLISLLRHSDRVVAACQAQLVNVIAPIRSEPGGPAWRQ
                     TIFHPFALTSRLARGDVLRTQVTAPSQETARFGDVPVVDAVATHDRASGDAVVFVVNRH
                     RTEPVELRVPLAAFGDVEVAEVWTVSDEDTTATNTEQDPDRVVPRQGTADVDDDGLVVV
                     LPPVSWTVVRLARR"
     gene            complement(9943..10821)
                     /locus_tag="CLV43_RS28865"
                     /old_locus_tag="CLV43_109141"
     CDS             complement(9943..10821)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800766.1"
                     /locus_tag="CLV43_RS28865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_109141"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_245887066.1"
                     /transl_table=11
                     /translation="MTAAVRVRSRRFGEPNPRVPHVVMAAGMLYFLVPLLWVLIAATKS
                     QPDLLSSPALWFGRGFALFDNIGQLFREDDGIYGRWLVNTALYSGASAVGATVLAAFAG
                     YGLARFSFWGKRFFETALLGMIMVPATALVLPTYLILSRLGIVNTVWAVILPSLLSPFG
                     AYLVRVYVTESVPVELIDAARVDRASELRIFWQIVVPMIRPAIVTVFLFTLVATWNNYF
                     LPLVMLSDADLYPLTVGLTTWFNTAQQEAGTRVLFNLVVTGALLAIVPLVIAFVLLQRF
                     WRGGVGAGALK"
     gene            complement(10818..11780)
                     /locus_tag="CLV43_RS28870"
                     /old_locus_tag="CLV43_109142"
     CDS             complement(10818..11780)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800765.1"
                     /locus_tag="CLV43_RS28870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_109142"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_245887067.1"
                     /transl_table=11
                     /translation="MTRALPGTAPKAGGAPGRRTVERVPRRRSRGVTAHSLAGMLFVLP
                     FFLVVVAFLVVPLGFALYLSFFTKSLVLGSRFSGLDGYLRAFTDPLLLDGFLRVLLFGV
                     VQIPVMLGIALAGALALDAITTRFAMLYRLFAFMPYAVPAVIGALMWGFLYSRTFGPFS
                     GVTSLFGGDPVDFFSGPLLLVSLGNVVTWAWTGYNTIVMHSALQGVPREMYEAAVIDGA
                     SPVQIALRVKVPAIRQAISLAAIFTVIGTMQFFTEPQIMARFAPQISAGYTPNLYAYNQ
                     AFAYSNFNYSATISFTLGFVVFVVAYAFVFVSRRRGARS"
     misc_feature    11768..11780
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.39"
                     /tool="antismash"
     misc_feature    complement(12118..12127)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 tcggcaccac gatccggacc aggacctgcc acttgttcgc accgtcgatc cgggccgcct
       61 cgaggatctc gcgcgggaac gcgacgaagg tggacgacag caggtaggtg ccgaacgcgg
      121 cctggacgat cgtgaacacg atgaccacgc cgagccgggt gtcgtacagg tcgacctgct
      181 tgaacaggta gtagagcggg tagaccagcg cctcctgcgg cagcgtgttg gcgatcagga
      241 acagcaccag cacccagagc cgccccttga tccggccgat ccccaacgcg taggcgttca
      301 gcaccgagac cacgaccgcc agcaccgcga ccgacccggc gatcagggcg ctgttgacca
      361 gcttccggcc gaagtccacg cgctgccaga agtcgacgat cccctggatc cgcacctcct
      421 ggggcagcga cagcggcccg ttggcggcgt agtccgcggg cgccttgacc gcgttcagca
      481 cgacgatcgc gaacgggacc agcatgaggc ccgccagcgc gacgagcccg atcagcacca
      541 ggtagcgccc cggttcgcgg cgcgcgtgca cggtcgccat cagctgtcct ccctgcggtt
      601 ctgcacgcgc aggaagaacg cggtgagcag caggatcagg acggtgagca cggtggcgac
      661 cgccgcgccg tacccgaccc tggtccgctc gaagaagttc tggaacgaga agtacgacgg
      721 cacgttcgtc gcgccagccg gaccgcccct ggtcagcacg tagatcggcc cgaacacctt
      781 gagcgccgcg atggagcacg tcagcatcac cacgaacacc tcggggcgga tgccgggcac
      841 ggtcacgtgc cagaaccggc cccaccacga ggcgccgtcc agctcggccg cctccagcag
      901 cgccgggtcg acccgctgca tgcccgccat gaagatgacc accgggtagc cgagctggat
      961 ccacaccagc acgcccatca cgctgtacag cgcgatgtcc gggtcgccga gccagtcccg
     1021 cgccagcgag ccgagcccga cggcgtcgag gaacgcgttg agcgcgccgc ccttcggggc
     1081 caggatccag ctccacacga tgcccgcgac cgcgatcggc agcacctgcg gcaggtacac
     1141 gcacgcccgc aggacgctgg ccgtgcgcgg gccgaaccgc ttgccgacga agtcgaacag
     1201 cgccgcggcg acgaccagcc cggcgatcgt cggcaggatc gccatggcga cgaccaaccc
     1261 gacgttgtgc cggaaggagg cccagaaggc gctgtccgcg aacagcttcc ggtagttctc
     1321 caacccgatc cacacgggat cgcccacgcc ggaccagcgg gtgaggctga tgccgacgtt
     1381 catcgcgaac ggcacgacca ccacggcgag cagcaggagc gcgccgggga ccaggaagac
     1441 caggtagccc ccgcgtccgc cgctccgcca tggcggcgcg gaccgggtgg gctccgcggg
     1501 ggacggccgg tcgacggccg gggcgaggct catccgccga tgttcgcgcg gttttccgcg
     1561 tacggcttcg ccagttcgtc gagcacctgg gaggggctcg cggtgccggt gatgagcttc
     1621 tgcgtcgcgg acaccatcac gtcgtagtag ccgggcgcgg gccagtccgg gtagtaggcg
     1681 agcccgtcgt tcttggccag ggtgtcgaag tcgtcgttca gcgccttcgc cgcggggtcg
     1741 gtggacggcg tgccgccggg ggagatcggg atgcccccgg cctcgcggag cacgtcctgg
     1801 atctcagggg acagcgtgat gtcgatgaag tcgtaggcca ggtccttgtt cttcgacccc
     1861 gccgggacga cccactggtt gccgctcgac ccggcgttca gcttgttgcc cggccacagg
     1921 aacgagcccc actggaagcc cgtggcgccc gcggccacgc ggccctgcca ccagctgccg
     1981 gacaccatga tcgggaactt gccctggatg aacgacagcc ccatgtcctc ggccttgacg
     2041 ccgctggcct ccgggctgat gtacttcttc gccacccagt cggcgaacgt ggtcgcgccg
     2101 taggtccagg cggcgtcgtg gaagtcgacg tcaccggtgt agcgctggta gcggtccacc
     2161 cacgcgcggt cggccttgct cagcgcgagc tggtagagga cctgctgggc cgggtactcg
     2221 ccgccgccga cggccaacgg ggtcacaccc gccgccacga acgcgtccat cgcggcggtg
     2281 aactcggcga acgtcttcgg caccgcgacg ccgcgcgccg cgaacatgtc cttgttgtag
     2341 tagaccgtga cgtactcggc gtagttgggg atcccgaacc acttgcccga ccccatcaca
     2401 ccccgctcgt cgtactgcga ggtcgtcttc aggttgggcg ccatgagctt gtcccagccg
     2461 cggccggaga cctgttcgct caggtccgcg agcagcccct gcctggacag cagaccggtg
     2521 gtcgcgttgc ccttgttgta ctccaggatg tccggcgcct cgttggagtt gagcaccatc
     2581 ggggcggtct tctggatctg ctcgaagccc ttctcctcga acgcgacctt cactccgggg
     2641 tgcttctcct cgaacttcgc gatggccgcg gcccacgcct tgcccatcgc gctgtccggg
     2701 tcctcgtagt gccagagctt caacgtcttg gggtcggagt cgccggagga gccgccgcac
     2761 cccgacaccg ccaacagggc gacgaccagc gccgcgaaca gtcgtgtgga catcaggcat
     2821 tcctcccgaa ggaccgcagt gttccgcgcg gcggattccg atcccgtggt cgacgggaat
     2881 tgttctcgtg gccggaaacc gttgcccaca aaaggggaac gggcggtcgg gtcgaccgcc
     2941 gttccgttcg cgtgaatcgc tttggtgccg cgccacgatg ttagcgataa cacctggtcg
     3001 gtggcgttgt cggcgcggaa aaaggccgcc cgtgaccaca accggccacg gctcttggcg
     3061 gacccctggt tccggtgtag gtccggtgag gactagagga cgaacccctc cgggaacggg
     3121 tcggtcgggt cgagcaggta ctgggccatg ccggtgatcc aggcccgccc ggtgatcgtg
     3181 ggcacgaccg cgtccacgtc gccgacgcgc tcggctcgga ccagccggcc ggtgaacctg
     3241 gtgcccagca acgactcgtt cacgtggtcg acgccgagct ccagctcgcc gcgcgcgtgc
     3301 agctgggcga gccgggccga cgtaccggtg ccgcagggcg agcggtcgaa ccagccgggg
     3361 tgcacgacca tggcgttgcg cgagtcgctg cccgcctcgc ccggcgcggt gagctggacg
     3421 tgcttgcagc cggagatcgc cgggtcgacg gggtgcacgg gccggtcggt cgcgttgatg
     3481 gccgccatga tgtccagccc gacggccagc atccggtcct tctcggcgcg gtcgaacggg
     3541 atgccgaggt ccgcgatcgg caggatcgtg tagaagttgc cgccgaaggc catgtcgtag
     3601 cgcaccggcc cgaggcccgg cacgtccacc acggcgtcct gcctgatggc gaacgacggc
     3661 acgttctcga tggtcacgga ctccgcacgc ccgtcccgca cgaccacccg cgcctcgacg
     3721 agcccggccg gggtgtccaa gcgcacgacc gtctccggtt cggtgacggt gaccatgccg
     3781 gtctccacca gcacggtcac cacgccgatc gtgccgtgcc cgcacatcgg caggcacccg
     3841 gacacctcga tgtagagcac gccccagtcc gcgtccggcc tggtcggcgg ctgcaggatc
     3901 gccccgctca tcgcggcgtg cccgcgcggc tcgttgacca ggaaccggcg gaggtggtcc
     3961 atgttctcga tgaagtgcag gcgccgccgc gccatggtgt cgccggggac cacgccgacc
     4021 ccgccggtga tcacccgcgt cggcatgccc tcggtgtgcg agtcgacggc ggtcaacgtc
     4081 cggaccgaac gcatgtcaga cccccttcag gtggtcgaag gcgcgccgca ggtcggcgtc
     4141 gagcacgtcg agctgagcgg cggacagcgg cccgcgggga ggcctgcacg gtccgccgaa
     4201 gcgcccggcc tggtccatgc cgcgcttgat cgcctgcacg aactcggtgc gcgagtccca
     4261 gcggaacgcg gccaccagcg gctcgtacag ctcacgcgcc tcctcgacct ggccggtggt
     4321 cgccagctcg tagagccgcg cggactcggc cgggaagacg ttcgggaacc cggcgaacca
     4381 gccggtcgcg cccatcagca gcgactccac caccacgtcg tccgcgcccg ccaccacggt
     4441 cagccccggt gcccgttcgc ggatctccag cacccgccgc acgtcaccgg agaactcctt
     4501 gaccgcgacc acgttgtcga tcgcggcgat ctcggtcagc agctccgggg tgaggtcgac
     4561 cttggtgtcg aacgggttgt tgtagaccat caccggcagg ccgacggacg cgacctcggt
     4621 gaagtgcgcg acgacctcgc gggcgttggc ccggtacagc gtgggcggca ggcacagcac
     4681 gccgtccgcc ccgtcctcgg cggccagctc ggcccagcgc cgcgcctggt gcgagcccgc
     4741 cgcgtgcacc ccgaccacga cggtcgcgtc accgccgacc gcggcgatcg cggtccgggc
     4801 gacctcccgg cgttcggcgt cggtgagcga ggagtactcg ccgagcgagc cgttcgggcc
     4861 gacgccgcga cagccgttgt cgaccaccca ccggcagtgc tcggcgtagc ggtccaggtc
     4921 cggccgcagc cccgcgggcg cgctcgggtc ctcgatgtag ggcagggcgg tcgccacgat
     4981 gacgccgtcg agacgttcgg tcacaggtcc tcctcgggca gcaggggtgt gtcggcgagc
     5041 tcgccgagcc gcagcggagt ggcgagcggt cggcggtgga aggcgtccgc gtcgggcagc
     5101 gggtggccga gccgggcggc ggccaggtcg gcgacctcgc ggccgcacac gcggccctgg
     5161 cacagcccga gcccggcccg actggccagc ttcagggtgc gcacgtcggc cgcgccccgg
     5221 tcgagcgcca cgtccaggtc gtgcgcggtg acctcctcgc accggcacac caccgtgtcc
     5281 gccagcagcc agccgtgccg tcccccgccc accgggtgcg cggccaccaa cgccatcgcg
     5341 aaccgcctgc cccgacgtac cgcgcgcatc gccgcgatcg gcggctcggg tgcgcgggcc
     5401 gccgccgagc ccgcgacagc gccttcggca gccgcgaggt cggcgccgcc gatgccggtg
     5461 acctcccccg ccgcgtacac gccggggacc gaggtcgcgc cggtggcgtc gaccgcgacg
     5521 aacccgtcca ccaggcggca gccgagtccc acggccagct ccaggcgcgg ggtgaagccg
     5581 tggccgacgc acacggcgtc gaccgcgacc cggcggcggg tgccgtcgac gaccgaccag
     5641 tccggccgca gcctggcgac cgtgaccgcg gtgacccggt cgtcgccgtg cgccgcgacg
     5701 accgcggcac gggtgcggac cgggatccgg tggcgtccga gcacgcccgc gtaccgcgcc
     5761 agctcgccca gcttgccgac gttcgccagg gtgtgcggat accgcgccca agtgctgaag
     5821 gcgttggcct ccagcacttc caggacctgc gtaccgaccc ggaccagcga ctcggcgacc
     5881 ggcagcagga acgggccggt gccggagacg acgacccgcg tgccgaccgc gacaccctgg
     5941 cccttcgcca acgcctgcgc ggcgccggcg gtgtagacgc cggggaggtc ccagccgggg
     6001 aacgggacga cgcggtcgtg cgcgccggtc gccagcacga cggcgtcggc gtcgagcacg
     6061 tgcggagtcc ggtgtggact gtccgcggga ccgcggcgga cgtgcaaccg caagccttcc
     6121 accgcccaca cggtgctgct cgccaggtgc cgcacgcggg agtccacccg ctgcggggtg
     6181 ccccggtggt actggccgcc cggccacggc tcggagtcga cgagcacgac ctccgcaccc
     6241 gcccggaccg cggcgtcggc ggcggccagc ccggcgggtc cgccgccgac cacgactacc
     6301 ctcacgtcgg cagctccgcc ccgtgctggg tgcggacgac gtcgccgtcc gcgggatagc
     6361 gcaggcacgc gcggacgtcg ggcacgccgt tgaccacgac gaggcagtcg aagcagaccc
     6421 cgatgccgca gaacaccccg cgcgggcggt ccccgttcct ggtggtgcgc cacgaggaac
     6481 ggcccgccgc gatcaggacg ccggcgatcg tccggccggg tggcacgtcg tgcggttcgc
     6541 cgtcgacggt gatcctcatc cgagcacccc cggtcggtcc actcggaacg gtgtcgggtc
     6601 caggtgcggc tcggcgccgg tgaccagctc ggtcagcagc ctaccggtcg cggccgccag
     6661 gccgatgccc gcgccctcgt gcccggtcgc gtgccacagc cccgcgcacc gcgggtcggc
     6721 gccgacgacc ggcaggtggt cgggcgcgta cgggcggaac ccgccgtagg cgcgcacgac
     6781 cggcacgtcg gccagtaccg ggaacagccc cacggcccgc cgggccaagg cacgcagcac
     6841 ctcgacgcgg atcgagtcgt cgaacccgac ccgctgcctg ctcgacccga tgagcaccgt
     6901 gccccccgcc gtcgactcga ccaccgtgga gatctgcagg tccgcgtcac cgctggcgac
     6961 cgcgcccacg tagtccgcgt cgtacacctt gtgccgcacg gtcggcggca gcgcggcggt
     7021 caccaggatc acgccccggc gcggcagcac ggtgatcggc gcgccgaacg cggcggacac
     7081 ctcgcccgac cacgggccgc aggcgttgac cacgatgccg cagggcacgt ctcccccggc
     7141 ggtgcggacg gcgaccaccc ggtcgtcgcg gcggcgcagg ccggtggccc gcactccggg
     7201 acgcagggtg ccgccgcgtc ggcgcaccgc cgcgagcagc gccttcgtca ccagcacggg
     7261 ttgcagctgg gcgtcctgcg ggtagtgcac ggccgccacg accgcagggg tcaggtgggg
     7321 ttcgcgctcg tgcgcctcgt ccggggtgac cacgcgcgcg tccacgccct cgggtcgttg
     7381 gtccgcggcg aacccgagca acgccttcgc cgcctcgtca ccggtcgcca cgaccaggcc
     7441 gcccttggcg tcccactcca cgtccacgcc cagctcgtcg agcagcgcgg gccagcggcg
     7501 cagcgacgcc agtgcgaggt cgagctcggg gccgggtccc ttgtcggaca ccaggacgtt
     7561 gccctcaccg gcggcgctcg tgcccgcgcc gagcggcccc cggtcgagca cggtcacccc
     7621 ggcgcccgcg gcgctcaacg cctcggcgca ggccgcgccg atgacgccgg agccgaccac
     7681 gaccacgtcc gggtaccgca ctcgcactcc aatcgttcat tgaagtgaac gcttcgagcg
     7741 taggcgcggg tccggcgcgg ggtcaatccc cgtgcgcggc ccgtccgggg tgcgcaccgt
     7801 ccggatgttc cagcagcagg accgactcca ccgggccgcc gacggtctcg taggtgtgcg
     7861 gggtctgggc cgggaagcag acgtagtcgc ccggtcccag ctcgtacggc gcggccggcg
     7921 ggccgacccg gagcacaccg gaggtgacca gcacgtgctc gcggccgggg tggcccgccg
     7981 agtactgggt ctgccccggt cggacgcgct ggtcgtagac ctcgacgacg gtctcgccga
     8041 tggtcagcct gcggaccatg cgcaggtcga cggcgttgct ggagagcacg tccaggtcgg
     8101 cggcgcgcac cagcacgacc tccgagtcga ccggcgcggt gagcagatcg gacaccggca
     8161 cgccgagagc gttcgacaaa ctgaacaccg tgtcgatggt cgggttgccc gtccccgact
     8221 ccagctggga cagcgtgccc ttcgcgatgc ccgaccgccg ggccagctcg gacagcgaca
     8281 gaccgccgtg ctcgcgcagc gcgcgcaggt tcgtcgccag cacctgcccg gcctgctccc
     8341 tgaccacccg gagtcctccc actcggccat ccccgcccgt ccggcgagca cggtacccgt
     8401 gactacctcc gggcgagccg cacgacggtc caggagaccg gggggagcac gacgaccagg
     8461 ccgtcgtcgt cgacgtccgc ggtgccctgc ctcggcacga cccggtccgg gtcctgctcg
     8521 gtgttggtcg cggtggtgtc ctcgtcggac accgtccaca cctccgcgac ctccacgtcc
     8581 ccgaacgccg cgagcgggac ccgcagctcc accggctcgg tccggtgccg gttcaccacg
     8641 aacaccaccg cgtccccgga cgcccggtcg tgcgtggcga ccgcgtcgac caccgggacg
     8701 tccccgaagc gcgcggtctc ctggctcggc gcggtgacct gcgtccgcag cacgtcgccg
     8761 cgcgccagcc gggacgtgag cgcgaacggg tggaagatcg tctgccgcca cgccggacca
     8821 cccggctcgc tgcggatcgg cgcgatcacg ttgaccagct gcgcctggca cgcggcgacc
     8881 acgcggtcgc tgtgccgcag caacgagatc agcaggctgc ccaccacgac ggcgtcggtg
     8941 acgtcgtagg tgtcctcgat cagccggggc gcggtccgcc actggacggg cgggtcggcg
     9001 tggaagcgct tctggtacca gacgttccac tcgtcgaacg acaccccgat ccgcttggcg
     9061 ctcttgagcc gcgcgccgac ggcgtccgcg gtggcgacca cgctgtcgat gaagcggtcc
     9121 atgtccaccg ccgaggcgag gaagctgtcg acgtccccgt cgtgcacctc gtagtaggcg
     9181 tggcaggaga tgtggtcgac ctggtcgtag gtcagctcca ggaccgtgga ctcccagtgg
     9241 ccgaacgtcg gcatggccga gctcgagctc ccgcaggcga cgagctccag ccccggttcg
     9301 gcctggcgca gcgcccgcgc ggtctcggcg gcgagcctgc cgtactcgtg cgcggtcttg
     9361 tgcccggtct gccacggccc gtccagctcg ttgcccaggc accacagcgc caccccgtgc
     9421 ggcgcctcgg acccgttggc gcggcgcagg tccgacagcg ccgtgccgcc ctcgtggttg
     9481 acgtactcgt ggacgtccag cgcctcctgg acgccccgcg tgccgaggtt gaccgcgtac
     9541 atgacctcga cgtcggcctt gcgcgcccac cgggcgaact cgtcgatccc cacctcgttg
     9601 gtctcgacgc tgcgccacgc gaggtcgcgg cgcgccgggc ggtcggcgac cgggccgatg
     9661 ccgtcctccc accggtaggc ggacacgaag ttgccgccgg ggtagcggac cagtgcgaca
     9721 ccgagctcgc gggtcagcgc gagcacgtcg ccgcggaacc cgtcctcgtc ggcggtcggg
     9781 tggcccggct cgtagatgcc cgtgtagacg cagcggccca tgtgctcgac gaacgacccg
     9841 aagagcctgc gccgcaccgg cgcgatcacg aagtcggggc tgagggcgag ggaggcggtg
     9901 agcacggttc tcctgcgggg tcgcggaact ctcggacagg gtctacttca gcgcaccggc
     9961 accaacgccg ccacgccaga agcgctggag cagcacgaac gcgatgacca gcgggacgat
    10021 cgccagcagc gccccggtga ccacgaggtt gaacagcacc ctcgtgcccg cctcctgctg
    10081 cgcggtgttg aaccacgtgg tgagcccgac cgtcaacggg tagaggtcgg cgtcgctgag
    10141 catcaccagc ggcaggaagt agttgttcca cgtcgccacg agcgtgaaca ggaagaccgt
    10201 gacgatcgcg ggtcggatca tcggcaccac gatctgccag aagatcctca gctcggacgc
    10261 ccggtcgacg cgggcggcgt cgatcagctc gaccggcacg ctctcggtga cgtagacccg
    10321 gacgaggtag gcgccgaacg ggctgagcag cgagggcagg atgaccgccc acaccgtgtt
    10381 cacgatcccc agccgggaca ggatcaggta ggtcggcagc accagcgcgg tggccgggac
    10441 catgatcatg cccagcagcg cggtctcgaa gaaccgcttg ccccagaacg agaagcgggc
    10501 cagcccgtag cccgcgaacg cggcgagcac cgtggccccg accgcgctcg cccccgagta
    10561 cagcgcggtg ttgaccagcc agcgcccgta gattccgtcg tcctcgcgga acagctgccc
    10621 gatgttgtcg aagagcgcga acccgcggcc gaaccacagg gcggggctgg acagcaggtc
    10681 cggctggctc ttggtggccg cgatcagcac ccacagcagc gggacgagga agtagagcat
    10741 ccccgccgcc atcacgacgt gcggcacccg cgggttcggc tcgccgaacc ggcgcgaccg
    10801 cacccggacc gccgcggtca cgagcgcgct ccccggcggc ggctgacgaa cacgaaggcg
    10861 taggccacga cgaacacgac gaagccgagc gtgaacgaga tcgtggcgga gtagttgaag
    10921 ttcgagtacg cgaacgcctg gttgtaggcg tacaggttcg gcgtgtaccc ggccgagatc
    10981 tgcggcgcga acctggccat gatctgcggc tcggtgaaga actgcatggt cccgatgacg
    11041 gtgaagatcg cggccagcga gatggcctgc cggatcgcgg ggaccttgac ccgcagggcg
    11101 atctgcaccg gtgaggcacc gtcgatcacc gccgcctcgt acatctcgcg cggcacgccc
    11161 tgcaacgccg agtgcatgac gatcgtgttg tagccggtcc acgcccaggt gacgacgttg
    11221 cccagcgaca ccagcagcag cggaccgctg aagaagtcga ccgggtcccc gccgaacagg
    11281 ctcgtcacgc cgctgaacgg gccgaacgtc ctgctgtaca ggaaacccca catgagcgcg
    11341 ccgatgacgg ccgggacggc gtagggcatg aacgcgaaca gccggtagag catcgcgaac
    11401 ctggtggtga tcgcgtccag cgcgagggcg cccgcgagcg cgatgcccag catgaccggg
    11461 atctgcacga cgccgaacag caggacgcgc aggaaaccgt ccagcagcaa cgggtccgtg
    11521 aacgcgcgca ggtagccgtc gaggccgctg aaccgcgacc ccagcacgag gctcttggtg
    11581 aagaagctga ggtagagcgc gaacccgagc ggtaccacca ggaacgccac gacgacgagg
    11641 aagaacggca gcacgaacag catcccggcg agggagtgcg cggtgacgcc gcgcgacctg
    11701 cgtcgcggca cccgctcgac cgtccggcgg ccgggcgcgc caccggcctt cggcgccgtt
    11761 cccggcagtg cccgtgtcac ggggaacctc ctgtcgtcgg ccgcgtgcgg gctactgggt
    11821 gacggtgaaa ccctgctgct gggcgtaggc gacgacgttc ttctgcgtct cctccagcac
    11881 cgagccccac gacctgctgc ccgccatcgc ctcggcgctg cggtcgttga ggtcgccgaa
    11941 cacgaagtcc tggaagggcg tgtactggaa ctctccgagc ttctccgaca ccggcacgaa
    12001 gatctcgttc accttctgcc cggcgaagaa gtcgtaggcc ttgccggtga acgccgggtc
    12061 cgcggccacg ttcttgacca gcgggtagag gaaggccttg ttgaggccga cgtcccaggc
    12121 cgccttcgac gagccgaaca gctccctggc cacctcggtc gccgccttgg ggttcttggc
    12181 ctgcttggtg accgtgaacg tcgagccgcc ccagtcgccc tggtcgtcgg cgcccgcggt
    12241 ccactgcggc atcggcgcga cggcccactt gcccgcggtg ttcttcagcg acccggcgac
    12301 gtaaccgggg gtccagcccg ccgcggccca cgtccagtac ttgccggagt cgagcgccgc
    12361 ggtggcgtcg gcggtgaaga acgggtcctt ggccatcagg cccttctcga ccagaccgcc
    12421 gtggaggtcg aagaccttct tgcactccgg gctggtcagg ttgatcttca ccttctcctt
    12481 cgccgcggcc cgggagtagc cgtagggcct gcacccggcc tgccacatca gcccgttgat
    12541 ccagccgccg tcgctgccga agctcgcgat gtaggcgccg ggatccgcgg ccttgatcct
    12601 caccgcggcg tcggcgtact cggcccacgt cctgggcacc gggatctgga accggtcgaa
    12661 caggtccttg cggtacatca gcgccatggg cccgccgtcg a
//
