LOCUS       NZ_PVTF01000007        21089 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Umezawaea tangerina strain DSM 44720 Ga0180964_107, whole genome
            shotgun sequence.
ACCESSION   NZ_PVTF01000007
VERSION     NZ_PVTF01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Umezawaea tangerina
  ORGANISM  Umezawaea tangerina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Umezawaea.
REFERENCE   1  (bases 1 to 610673)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 610673)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Expected Final Version            :: No
            Genome Coverage                   :: 86.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003002815.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:47:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,483
            CDSs (total)                      :: 9,418
            Genes (coding)                    :: 9,322
            CDSs (with protein)               :: 9,322
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 20 of 97
            Pseudo Genes (incomplete)         :: 83 of 97
            Pseudo Genes (internal stop)      :: 2 of 97
            Pseudo Genes (multiple problems)  :: 8 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 489905
            Orig. end                         :: 510994
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVTF01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21089
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21089
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21089
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11089](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11089)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(1493..1507)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    1901..1916
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.81"
                     /tool="antismash"
     gene            complement(2071..5304)
                     /locus_tag="CLV43_RS25050"
                     /old_locus_tag="CLV43_107393"
     CDS             complement(2071..5304)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670127.1"
                     /locus_tag="CLV43_RS25050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107393"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_106189699.1"
                     /transl_table=11
                     /translation="MDGDTRLRATLLGAFRVSRGEVDLPVAGARLQGLLVRLALAGGRA
                     VEQGVLVDAIWAEDPPADPAHALQALVSRLRRALGSAGDVEQASGGYRLAVDDADVDAP
                     RFERLAAAGRDHLRAGDPNAAAEVLGEAVALWGDRPGAEPTAVVAVAPAAATRLAHASV
                     EAVADLAAAELSLGRADASTVRLTALLAEHPVHERAAALLMDALAVQGRQADALAVYER
                     VREALADVLGTDPGAALRERHLRLLRAEPPTPAPAAVAPTRPSTLPTPLTSFIGREDDL
                     ARITALLAAGRLVTVLGPGGAGKTRLAVEAVRSHRHDHRDGTWMVDLASVTEPAKVGAA
                     VLAGIGLRGGAMFEARVRLRGDELDVLVDQLGGRECLLLVDNCEHLVDAVAHLLTGLLT
                     RCPSLRVLATSREPLAVDGEALVPLGPLALPDPDDDVEQARKAASVRLFTERAAAVRPG
                     FTVDATTLPDVLRVVRGLDGMPLALELAAARLRTLSLPELADGLSDRFRLLTTGSRTAL
                     PRHRTLRAVIAWSWELLSEPERTVAERVSILPGGVTPDSAAAVCAGTAVRADGIPELLA
                     GLVDRSLLQLAPDPGRYRMLETIREYGTERLAEADDLGAVRDLAAGYSAGLMARYDPLL
                     RGPGQLTALRVVSAEYDNTLAALRRRCDTGDADGAVALVLTLTWYWQMFGRHPDAAYWL
                     GEALAVPGGRPSPDRDCALAVHLLNRVDPRPGMSAQDAEADRARVRELADRLLAHPELP
                     GPHGLLSAFTLALLEKVDAAVAAIERETDGEDLWLSGLARMLRAEYAENSGDLDRVRTD
                     VEEAITRFRQAGDRWGQATVLPMRAQLRQYDDDLDGALADLREARSLAGEFGSLSLGDE
                     VFVDLRWVDLHLRRGDTDLALAMIDSARERARPAHSPATVILVDAWEADFRIRVGDLDR
                     ARELLDEADLGLRDHPSFPGDHALTLTSSVRSALCLALGDLPGAHRALTTAYATALVID
                     DLPLLSVVAVHVAALAEARGLHHETAVLLGAASRLRGTHDRTDGQVRDLTRHGRAALGE
                     DAFAAAYSKGWELDRATALAEADPARLGR"
     gene            5431..6555
                     /locus_tag="CLV43_RS25055"
                     /old_locus_tag="CLV43_107394"
     CDS             5431..6555
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003070019.1"
                     /locus_tag="CLV43_RS25055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107394"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_106189700.1"
                     /transl_table=11
                     /translation="MTSHVTIIGAGLGGLTLARVLHVHGIPCTVHEAEASPAARTQGGM
                     LDIHDYNGQLAVRAARLTDEFRALVLEGRQAVRIVDRDGNALFDKGDDGTGGRPEVQRG
                     ELRRLLLDSLPEGTVHWGRKVGGVRALEEGRHEVTFADGDAVVTDVLVGADGAWSRVRP
                     LLTTATPRYTGESFVETYLFDADTRHPATARVVGGGSLIATGADRAIHAHRERGDTLHG
                     YISLTRPLDWFADIDFTDADAVAERVVAEFDGWAPELTALITDSDTPPVHRPFHALPPG
                     STWDRVPGATLVGDAAHLAAPNGEGANLAMLDGAELGEAIAAHPDDVETAFAEYERAMF
                     PRSADTNARFAGEAAVEDLIAFFGTAEVAGWGGR"
     gene            6748..8283
                     /locus_tag="CLV43_RS25060"
                     /old_locus_tag="CLV43_107395"
     CDS             6748..8283
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020499936.1"
                     /locus_tag="CLV43_RS25060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107395"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_106189701.1"
                     /sec_met_domain="DAO (E-value: 1.7e-11, bitscore: 39.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVLVVGAGPVGLFLACELGLAGCSVLVLEREPEPTTPWRAYPL
                     GMRGLSAGSVEAFHRRGMLPRLLTASGGNAAPGTDLDVESAAAEDEAPPPRSAGHFGGM
                     MLDPADVDVDSLPFRLPGPALEGVMTSLEAVESVLAERAAKLGVEIRRGVAVSAVTQDD
                     EGVIAHDGEHEHAARWLVGCDGGRSAVRGLAGFDFVGTDPMFTGYVMHADSPDAERLRQ
                     GFTLTPRGMYLRMPFPGHLAVQDFDGGAYDRSRPPTREHLQEVMRRVSGVDVTLDGIRL
                     ASTFTDRAMQTTTYRRGRVLLAGDAAHIHSPLGGQGLNLGIGDAVNLGWKLAATVRGDA
                     PDGLLDTYTAERHPVGARVLDWSRAQVAAIAPGPHTPALLGVLRDLLGTRDGTTYVHDR
                     LSGLSIRYDLGEDDPLVGRNAPEFRLREGTRLGDLLQDGRGVVLDFTADHRLRDSAAGW
                     EDRIRYVAGPARNDLGHGAVLVRPDGVVAWAGDREPDREAFGRAARRWFGEPV"
     gene            complement(8327..9106)
                     /locus_tag="CLV43_RS25065"
                     /old_locus_tag="CLV43_107396"
     CDS             complement(8327..9106)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015747.4"
                     /locus_tag="CLV43_RS25065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107396"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_106189702.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.5e-08, bitscore:
                     29.1, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLGGSPTRTENPNVSTTTVGIIGTGSVGAGVARLAVDAGLEVVL
                     ANSRGPETLTALIAGLGDQARAATPAEAARAADLVLAAVPLSVHERLPRAELAGKTVID
                     PMNYVPTPAWRSAELDGDELTSSGLVQRHLADSRVVKAFHSIGPKQLLDLRLPTGAPDR
                     TALPLSGDDPAAKAEVAALLDALGFDAVDLGGLADSWRGEPNTPLYCMPYVGTPPADLS
                     VPELVAWVQAAPGVPVSAARVEDLAAAAVRGPAGFRL"
     gene            9177..10025
                     /locus_tag="CLV43_RS25070"
                     /old_locus_tag="CLV43_107397"
     CDS             9177..10025
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804904.1"
                     /locus_tag="CLV43_RS25070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107397"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_106189703.1"
                     /transl_table=11
                     /translation="MELRALHYFVTVAEELHFGRAAERLRIVQPAVSQQITRLESELGA
                     RLFDRTSRRVRLTPAGERVLVTARATLAAAARVRVVARESAASLRIGMATCFTPRVDRA
                     LTRLREGGQLAEPTLVDLPVPARLDAVRDGELDLALVRGTLTSTAMTVVRAWSEPVHVV
                     LSREHRAAGKPAVGLHDLDPDGLRLLTRAADPPMHDAVLAALPEAPRRPPVVDTLNVLV
                     EVGQDPEGWTLLPVEQTTGSDSARLVQVPLDPPLSVDGSVVTPLATPAARVASYVAAFG
                     D"
     gene            complement(10001..11089)
                     /locus_tag="CLV43_RS25075"
                     /old_locus_tag="CLV43_107398"
     CDS             complement(10001..11089)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="CLV43_RS25075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107398"
                     /product="hypothetical protein"
                     /protein_id="WP_106189704.1"
                     /sec_met_domain="T1TS (E-value: 7.3e-69, bitscore: 228.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVRTAAPEVPPLYCPLPSAVHPLAADIGRRSIAWLDGLGLFEQ
                     EGLREHMIRTRAAEWACRIAPFGSEERLQIVSDWTHLGFAIDDCRFDAGALVERPGVLI
                     PLMMRLMPNLDHPEVAADDPFSAGFRDLSARARAAVPAAVVRRWVEGNMEWFFAVACLT
                     SYRVSGSMPSLADYVNLGPRDRAMRLTGSLIEIAEGTYLPDEDRERPEVRAATQAANML
                     VTIGNDLYSLSKETEHDVLESNIVGVIGHEDGCDAPEAVRRAVALHDRIMCRYLRLRRR
                     IGARGGDPVRRHLSQLDHLVRGNLEWSARVPRYRRAEHGERTSSPWADVPSDADPTAPP
                     IPGIAWWWDEIEEGAQSPNAAT"
     gene            complement(11086..12441)
                     /locus_tag="CLV43_RS25080"
                     /old_locus_tag="CLV43_107399"
     CDS             complement(11086..12441)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="CLV43_RS25080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107399"
                     /product="cytochrome P450"
                     /protein_id="WP_106189705.1"
                     /sec_met_domain="p450 (E-value: 2.3e-66, bitscore: 219.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKATATSTSAPPLAPGGAPLLGHVVPLLRHPLAFMDSLRRHGPVV
                     RIMLGRIPVFVVTDAGLTHEMLTAQASSFGKGGRLIEALSRFAGNGLATVADGDLHRTQ
                     RRLVQPMFSRAFIAGRGDTMIEVARSVVDGWAAGEPRELHDDMQELTLSVFLAALLGTE
                     PPEATRRRIQRVLPDVMAGTIRATILPPWLGSVPTPTQRRQRDSFTELRDAIGDLVDEH
                     RRPLRDKGLLDLLLDARDPDTGQPMSRRQLEDEVITFVTTNGQASTATVLWALHEIGRH
                     PAVRDRIVAELDEVAPGRPLVGADLGSLTYTRRVVHEAMRLYGPAWLLTRTVTAPASLG
                     GFDLPQGATVVFSPYILHRDPVVYPDPAAFDPDRWSPERARSIPRTAFQPFGGGARQCV
                     GESFAWSEMVIILAETTRRWRMVPDPAVVPRPVPRVTIHPHRLVMTPSGTGR"
     gene            12885..13031
                     /locus_tag="CLV43_RS25085"
                     /old_locus_tag="CLV43_107400"
     CDS             12885..13031
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018096.4"
                     /locus_tag="CLV43_RS25085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107400"
                     /product="DUF1059 domain-containing protein"
                     /protein_id="WP_106189706.1"
                     /transl_table=11
                     /translation="MKKNISCPCGERITGDDEDDLVAKTQQHLKENHPGHDYSRDEILF
                     MAY"
     misc_feature    complement(12886..12900)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            complement(13050..13886)
                     /locus_tag="CLV43_RS25090"
                     /old_locus_tag="CLV43_107401"
     CDS             complement(13050..13886)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645363.1"
                     /locus_tag="CLV43_RS25090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107401"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_106189707.1"
                     /transl_table=11
                     /translation="METRELRYFVAVAEELHFGRAAQRLGIAQPPLSRTIAQLEHRLGV
                     ALLERTSRKVSLTEAGSVLLTEGRAILGALAATERRTQQAATSRPSLVLATKAGASGEL
                     LAKLLDAYAAEPDAVAVDLLLCESQPQRPLHDGRADVALLHLPFDSTADLDTEILTTES
                     QVAVLPTSHPLASRSHLRTADVSALPDLPLARWPRADGSYPEGPGAEVHNQTQLFQLIA
                     LGRTTVVLPDSCRANLLEGLTAVPVLDAPPVTTVIAWPPHSRSRALADLVRVATQR"
     gene            13982..14701
                     /locus_tag="CLV43_RS25095"
                     /old_locus_tag="CLV43_107402"
     CDS             13982..14701
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227429.1"
                     /locus_tag="CLV43_RS25095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107402"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_106189708.1"
                     /transl_table=11
                     /translation="MSERTIALVTGANKGIGYEIAAGLGALGWSVGVGARDGQRRDDAV
                     EKLRAAGVDAFGVPLDVTDDASVAAAAALVEERAGRLDVLVNNAGVAGPWPAVPSTMSV
                     DAVRDVVETNVLGVIRVTNAMLPLLRRSGSPRIVNQSSHVGSLALQTAPGVELGGVDGV
                     YSPTKTFLNAVTVQYAKELVGVKVNCACPGYVATELNGFRGTSAAEEGARVAIRLATLP
                     DDGPSGGLFDGAGVVAW"
     misc_feature    complement(14997..15012)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.2"
                     /tool="antismash"
     gene            15178..15993
                     /locus_tag="CLV43_RS25100"
                     /old_locus_tag="CLV43_107403"
     CDS             15178..15993
                     /NRPS_PKS="Domain: PKS_KR (7-119). E-value: 4.1e-08. Score:
                     25.3. Matches aSDomain:
                     nrpspksdomains_CLV43_RS25100_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="CLV43_RS25100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107403"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_106189709.1"
                     /transl_table=11
                     /translation="MREWDGAVAFITGGAQGIGLGIARALGKRGVRLAVVDIDEEALGR
                     CGDELGEVGEVEVYRLDVRDRAAFASVADEVEGRFGGVDLLFNNAGVVPYSAVSELGYE
                     KWDLALGINVVGVVNGIQTFLPRMIGRGRGGYVVNTASGAGLVADANVLYVTTKFAVVG
                     LSESLRLALEGHGIDVSVLCPGPVDTGIVRNTRALDESAFTGLSDSAVQGVEAFLKSGV
                     SIDEVGEMVVAGMEARSAWIHTDAVVRTHVEQRMTAILDSIPVPAAGTP"
     aSDomain        15199..15534
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLV43_RS25100_PKS_KR.1"
                     /evalue="4.10E-08"
                     /label="CLV43_RS25100_PKS_KR.1"
                     /locus_tag="CLV43_RS25100"
                     /protein_end="119"
                     /protein_start="7"
                     /score="25.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAFITGGAQGIGLGIARALGKRGVRLAVVDIDEEALGRCGDELGE
                     VGEVEVYRLDVRDRAAFASVADEVEGRFGGVDLLFNNAGVVPYSAVSELGYEKWDLALG
                     INVVGVVN"
     CDS_motif       15208..15273
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CLV43_RS25100_0001"
                     /evalue="1.40E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="CLV43_RS25100"
                     /protein_end="32"
                     /protein_start="10"
                     /score="11.3"
                     /tool="antismash"
                     /translation="ITGGAQGIGLGIARALGKRGVR"
     gene            complement(15990..16658)
                     /locus_tag="CLV43_RS25105"
                     /old_locus_tag="CLV43_107404"
     CDS             complement(15990..16658)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="CLV43_RS25105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107404"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_170155998.1"
                     /transl_table=11
                     /translation="MSARGQRRIDEIGDESRRRILDAAEELFAERGFDRTSFVDIAERS
                     GISRGSIPWHFKNKAGLVVAVLERAIDRAMPPGLYKSVPPLTEVFEDSATLVREGNAGL
                     PFMILTEAIGTTGVVHAQYQDFFARRRDGLELWLRVQRPEGADPETAAKQERAFAVALH
                     GTLVGIHLQALIDPDGFDLDAALRSISAMVDKNLADVWTTPLTPHRRTANDRKARKRAD
                     "
     misc_feature    16624..16644
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.66"
                     /tool="antismash"
     misc_feature    16708..16722
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.36"
                     /tool="antismash"
     misc_feature    16744..16757
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.2"
                     /tool="antismash"
     gene            16757..17197
                     /locus_tag="CLV43_RS25110"
                     /old_locus_tag="CLV43_107405"
     CDS             16757..17197
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020422836.1"
                     /locus_tag="CLV43_RS25110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107405"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_106189711.1"
                     /transl_table=11
                     /translation="MDAPELTTSLDLVRWVVWAQRKAGEDWIRERGLSHEQSFVLGYLV
                     QSPGAIQRDIAEMTRTSAASVSSLVQGLERRGLVERRTEGGDVRSKRVYATPEGGELIA
                     GFSAAMAAVEETILAPLDQDERTTLHALLTKITAELPRPTRS"
     gene            17283..18440
                     /locus_tag="CLV43_RS25115"
                     /old_locus_tag="CLV43_107406"
     CDS             17283..18440
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417098.1"
                     /locus_tag="CLV43_RS25115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107406"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_106189712.1"
                     /transl_table=11
                     /translation="MTSHVTIIGAGLGGLTLARVLHVHGIPSTVYEAEASPTARAQGGM
                     LDIHDHNGQPALEAAGLSEEFRALVLEGRQAIRVLDRDGNLLFDKADDGTGGRPEVQRG
                     ELRRLLLDSLPEGTVHWGRKVGGVRALGDGRHEVTFDDGDTVVAELLVGADGAWSRVRP
                     LLSDAVPEYIGRSFVETHLHDGDTRHPAAAKAVGGGSLFALAPGKGIQAHRESGDTLHT
                     YVALCESQEWFAGIDFTDADAATARIAAEFDGWAPELTALITESDTPPVLRPLHSLPIG
                     HRWERVPGVTLVGDAAHLSGPNGEGANLAMYDGAELGKAIAAHPDDVEAALAEYEQDLF
                     PRGAEAAADGVQLHEFLFGANAPHSLVDAFLADDETSGGRLSSVD"
     gene            complement(18429..19727)
                     /locus_tag="CLV43_RS25120"
                     /old_locus_tag="CLV43_107407"
     CDS             complement(18429..19727)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /locus_tag="CLV43_RS25120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107407"
                     /product="acyltransferase"
                     /protein_id="WP_106189713.1"
                     /transl_table=11
                     /translation="MEPVLPTLRPISTIPRPPVAATPHRASRLGWLDALRGIAALVVAF
                     AHSSSSFQPELQRELMPTFNIGRFGIMVFFLVSGYIIPASLERRGDVRAFWIGRAFRIY
                     PLCAVAVGAVVVAGLAGLTEIRGGQDNAALAVAHLTLFQELLGTHNLLLVLWTLSYEMA
                     FYLLVVALFTVRQHQRSGAVAITLAVLAAVSVAAGVVLPVSMLSHVVGTGPLVALTSVT
                     MAVAIGCACSGSSALRVFGGVLGGVLGLTLVLLNGTVPVWEGLVILAVMFLGTAVHRAE
                     SGRSTWRYAACAAAVVVVCAVGSAYLHGDDPHFTRRGWIVAFLLALLTFGVGLASRHRR
                     VPRWLTGLGAISYSVYLVHPLLLAVHDGTFGRSRQDNLVLELAFYAVLLPLCVVTHRFI
                     EVPCQAWGRKVALRPPKLLGEVVDIRRGSRSVH"
     gene            complement(19795..20757)
                     /locus_tag="CLV43_RS25125"
                     /old_locus_tag="CLV43_107408"
     CDS             complement(19795..20757)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225180.1"
                     /locus_tag="CLV43_RS25125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_107408"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_106189714.1"
                     /sec_met_domain="PALP (E-value: 2.4e-72, bitscore: 238.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQTRLDLDRIHAARRVVDPMFLDTPLYPCDALGRQLGCTVSVKL
                     ETANPVRSFKARGTELVTSLLVEQGRTAVVCASAGNLGQALSWSGLRRGLDVAVVASKR
                     APATKLDRIRALGAELELVDGDIEVARARAADIARQRGIRLLEDSLDVETCEGAATIGL
                     ELAGAGPAFDAVLVALGGGAMASGVGHVLKTVAPGVEVICVQPAGAPAMTRSWHERRVV
                     TTDSLDTIADGVAGRFPIPEVLDDLLAVTDDAVLVRESSIIEGMRLLLEHTGLVVEPSA
                     ALGVAAVLEDRERFAGRHVVTIVCGGNVDLDAYHRWVRP"
ORIGIN
        1 cgggtcgacc cggaagccct gccgttcaca gcgatcgagc tgaccgggaa cgccgtggag
       61 ttcgccgcgt tcggcgagta ctggcgctgc gacccggagg gccgcacctg cgaacgggcc
      121 gagttcacgc cgccgggcaa cccgctggac gtgccgtcgc ccgacgggaa ggtcgccgtc
      181 tcccaacggg gtcacgacct gtgggcgcgg tcgctcaccg acggccgcga gtggccgttg
      241 acgaccgacg gcgcacccga ccaccgctac ggccccggac ccgccgccac cggcaacggc
      301 accctgctgc gcaagttcgg cctgccgcac ctgccgcccg cggtggcctg gtcgccggac
      361 tccacgaagg tgctggcgca ccggaccgac gagcgcgccg tccggctcgc ccacctggtg
      421 caggccaggc ccgccgacgg cggcgccccg gtgacgcaca cccagcggta cgcccacgcg
      481 ggcgacgagc acctgccgct ggccgagctg gtagtgctgg acgtcgccga gggggcggtg
      541 gtccgggcgc aggcggagcc gctgctgatg ccgaccacgt cgccgatcac ggcagggtgg
      601 gcgtggtggg cgccggacgg ctcggcggtg tactacctcg accggtcgcg cgacgcgcgc
      661 acgctctccc tgcgcaggct ggacccggcc accggcgagg tcacgaccgt gctcagcgag
      721 accggcgcca cccgcgtcga gcccacccag tggctctacg agccgccgat cgtgcgggtg
      781 ctggccgacg aggtgctgtg gtactcgcag cgggacggcc aggggcacct gtaccggtac
      841 gacctgcgca ccggggacct gctcgggcag gtcacctcgg gggagtgggc ggtgcgccag
      901 gtcctgcgcg tcgacgagtc cgaacgggtg gtccacttca cggcgaccgg gttggtcgag
      961 gaggacccgt accggcgcac cgcgtgccgg gtcgggctgg acggctccgg cttcgcggtg
     1021 gtcaccgacg acgggctgga ccacgtcgtc accccgtcgg ggaacgggga gtggttcctc
     1081 gactcggcgt ccactgtgga caccccgccg gtgacctcgg tccgcgactg gtccgggcgc
     1141 gtgctggtcg agctggaacg cgcggacgtc accgggctca ccgcactcgg ctggacgccg
     1201 ccggaacggt tccgcgtcaa ggcggccgac ggggtcaccg acgtctacgg cgtgctgtac
     1261 cggccgcacg gcttcgaccc cgcccagagc tacccggtcg tcgacaccct ctaccccggc
     1321 ccgcaggtca ccagggtcgc cccgtccttc gaccccggcg gcatgggcct ggacgcggag
     1381 cccttggccg cactgggttt cgtggtggtg gcgctggacg gtcgcggcac gcccggtcgc
     1441 ggcaaggcct tccacgacgc ctcctacggc aggctcgccg acgcgggcgg gctggccgac
     1501 cacgtcgcgg cgctgcggca gctcgccgag acccggccgt ggatggacct cgaccgcgtg
     1561 ggcgctttcg gccactccgg cggcgggttc gccgccgtcc gcgcgctgct ggacttcccc
     1621 gacgtgtacc aggtcggggc ggcgctctcc gggtcgcacg acccccgctg cttcaacccc
     1681 ggtttcgtgg agacctacga cggtgccgac gttcccggga cctgggcgcg ttcctccact
     1741 gtggacagcg cggaccggtt gaggggcagg ctcctgctcg tccacggcga gatggacgac
     1801 caggtgcacc cgcaccacac gatgcggctc gcggaccggc tcgtcgccgc ggacaaggac
     1861 ttcgagctgc tggtcgtgcc gggtgccgag cacaccttca tcgactgcct gtcctacgtc
     1921 cgcaagcact gctgggactt cctggtccgc gagctgatgg gcgtgcgccc gcccgcctac
     1981 cgccccgcgc ccatcccgat cgggccggag ctgctcgccg agatgttctc ctgagccggg
     2041 gtgaccggtc cgggtcgcgc gggcgccggg ctaccggccc aaccgggccg ggtcggcctc
     2101 ggccagcgcc gtcgcccggt ccagctccca gcccttggag tacgcggcgg cgaaggcgtc
     2161 ctcgcccagc gcggcccggc cgtgacgggt gaggtcgcgg acctgtccgt cggtgcggtc
     2221 gtgggtgccg cgcagccggg aggcggcgcc gagcagcacg gcggtctcgt ggtgcagtcc
     2281 gcgcgcctcg gccagtgcgg ccacgtgcac cgcgacgacg gacagcagcg gcaggtcgtc
     2341 gatcaccagc gcggtggcgt aggcggtcgt cagcgcccgg tgcgcgccgg gcaggtcgcc
     2401 cagcgccagg cagagcgcgg agcggacgct gctggtcaac gtcagggcgt ggtcgccggg
     2461 aaagctgggg tggtcgcgca ggcccaggtc ggcctcgtcg agcagttcgc gagcccggtc
     2521 caggtcgccg acccggatcc ggaagtcggc ctcccacgcg tcgaccagga tcaccgtcgc
     2581 cggggagtgg gcggggcgcg cccgctcccg cgccgagtcg atcatggcga gcgccaggtc
     2641 ggtgtcgccc cggcgcaggt gcaggtcgac ccagcgcagg tcgacgaaca cctcgtcgcc
     2701 gaggctgagg gagccgaact cgcccgccag cgagcgggcc tcgcgcaggt cggcgagagc
     2761 gccgtcgagg tcgtcgtcgt actgccgcag ctgggcgcgc atcggcagca cggtggcctg
     2821 gccccagcgg tcaccggcct gccggaagcg ggtgatcgcc tcctccacgt cggtgcggac
     2881 ccggtcgagg tcgccggagt tctccgcgta ctcggcccgg agcatgcggg ccagccccga
     2941 cagccacagg tcctcgccgt cggtctcgcg ctcgatggcc gcgaccgcgg cgtccacctt
     3001 ctccagcagc gccaacgtga acgcgctgag caggccgtgc ggtccaggca gctccgggtg
     3061 ggcgagcagc cggtcggcca gctcgcgcac ccgcgcccgg tcggcctcgg cgtcctgcgc
     3121 gctcatcccc ggtctggggt cgacccggtt gagcaggtgg accgccaggg cgcagtcccg
     3181 gtccggcgac ggccgtccac cgggcaccgc cagcgcctcg cccagccagt aggccgcgtc
     3241 ggggtggcgg ccgaacatct gccagtacca ggtcagggtc agcacgaggg cgaccgcgcc
     3301 gtcggcgtcg ccggtgtcgc accgcctgcg cagggccgcc agggtgttgt cgtactcggc
     3361 gctgacgacc cgcaacgccg tcagctggcc cggtccgcgc agcagcgggt cgtaccgggc
     3421 catcagcccg gcggaatagc ctgcggccag gtcgcgcacg gcacccaggt cgtccgcctc
     3481 ggcgaggcgt tcggtgccgt actcgcggat ggtctccagc atccggtagc ggccggggtc
     3541 gggcgccagc tggagcagcg accggtcgac caggcccgcc agcagctcgg ggatcccgtc
     3601 ggcccgcacc gcggtacccg cgcagaccgc ggcggccgag tccggggtga cgccgcccgg
     3661 caggatcgag acgcgttcgg cgaccgtgcg ttccggctcg ctcaacagct cccagctcca
     3721 ggcgatgacg gcgcgcaggg tgcggtggcg ggggagtgcg gtgcggcttc cggtggtgag
     3781 caggcggaag cggtcggaga gcccgtcggc cagttcgggc agggacaggg tgcgcaggcg
     3841 ggcggcggcc agttcgaggg ccaggggcat cccgtccagg ccgcgcacca cgcgcaggac
     3901 gtcgggcagg gtcgtggcgt ccacggtgaa accggggcgc acggcggcgg cccgttcggt
     3961 gaacaggcgc accgacgccg ccttgcgcgc ctgttcgacg tcgtcgtccg ggtcgggcag
     4021 ggcgagcggg cccagtggca cgagggcttc gccgtccacg gccaggggtt cgcggctggt
     4081 ggcgagcacg cgcaacgagg ggcagcgggt gagcagcccg gtgagcaggt gggctacggc
     4141 gtcgaccagg tgctcgcagt tgtccaccag cagcaggcac tcccggccgc cgagctggtc
     4201 gacgagcacg tccagctcgt cgcccctgag ccgcactcgc gcctcgaaca tcgcgccgcc
     4261 gcgcagcccg atcccggcga gcacggccgc gcccaccttg gcgggctcgg tgaccgaggc
     4321 gaggtcgacc atccaggtgc cgtcccggtg gtcgtggcgg tgcgagcgga cggcctcgac
     4381 ggccaggcgc gtcttgcccg ctccgccggg gccgagcacg gtgaccaggc gcccggcggc
     4441 gagcagcgcg gtgatcctgg ccaggtcgtc ctcacggccg atgaaactgg tcaacggggt
     4501 gggcagggtg ctgggacggg tcggcgcgac cgcggccggg gcgggggtgg gtggctcggc
     4561 gcgcagcagg cgcaggtggc gctcgcgcag ggcggcaccg gggtcggtgc cgaggacgtc
     4621 ggccagcgcc tcgcggaccc gttcgtacac cgccagcgcg tcggcctgcc gaccctggac
     4681 ggcgagcgcg tccatcagca gcgcggccgc ccgctcgtgc acggggtgct cggcgagcag
     4741 ggcggtcagg cggacggtgg aggcgtcggc ccgcccgagg gacagctccg cggcggcgag
     4801 gtcggcgacg gcctcgaccg aggcgtgggc cagccgggtc gcggcggcgg gtgccacggc
     4861 gacgacggcc gtgggctcgg caccggggcg gtcgccccac agcgcgacgg cctcgccgag
     4921 gacctccgcc gcggcgttcg ggtcacccgc gcgcaggtgg tcgcggcccg cggcggccag
     4981 ccgttcgaac cgcggcgcgt ccacgtcggc gtcgtccacg gccagtcggt agccgcccga
     5041 ggcctgctcg acgtcgcccg ccgacccgag ggcccggcgc agccgcgaga cgagggcctg
     5101 cagggcgtgg gccgggtcgg cgggcgggtc ctcggcccag atcgcgtcga ccagcacccc
     5161 ctgctcgacc gcacggccac cggccagcgc cagccgcacg agcaggcctt gcagccgcgc
     5221 gcccgcgacg ggcaggtcga cctcaccgcg ggacacccgg aaggcgccga gcagcgtggc
     5281 gcgcagccgc gtgtccccgt ccatcccacg atcttcgcct gcccgccccc gagtccccaa
     5341 accagggcgt gaggccgtgt gagcgcgctg tgcacccggt gtgagcggca cgcgtcagcc
     5401 ttcggaggcc tcgaaccgaa ggaggagcac atgaccagcc acgtcacgat catcggtgcc
     5461 ggactcggcg gcctcaccct ggcccgcgtc ctgcacgtcc acggcatccc gtgcaccgtc
     5521 cacgaggcgg aagcctcgcc cgcggcgcgc acgcagggcg ggatgctcga catccacgac
     5581 tacaacgggc agctcgccgt ccgggccgcc cggctgaccg acgagttccg cgcgctcgtg
     5641 ctggagggcc gccaggcggt ccggatcgtc gaccgggacg ggaacgccct gttcgacaag
     5701 ggagacgacg gcacgggtgg tcgtcccgag gtgcagcgcg gtgagctgcg ccggttgctg
     5761 ctcgactcgc tgccggaggg caccgtccac tggggacgca aggtgggcgg tgtccgggcc
     5821 ctggaggagg gccgccacga ggtgaccttc gccgatggcg acgcggtcgt caccgacgtg
     5881 ctggtcggcg cggacggcgc gtggtcgcgg gtgcggccgc tgctcaccac cgcgaccccg
     5941 cggtacacgg gggagtcgtt cgtcgagacc tacctgttcg acgccgacac ccggcacccg
     6001 gccaccgcgc gggtggtcgg tgggggctcg ctgatcgcga cgggggcgga ccgggcgatc
     6061 cacgcccacc gggagcgggg cgacaccctg cacggctaca tctcgctcac caggccgctg
     6121 gactggttcg ccgacatcga cttcaccgac gccgacgcgg tggccgagcg ggtcgtggcg
     6181 gagttcgacg gctgggcgcc ggagctgacc gcgctcatca ccgacagcga cacgccaccg
     6241 gtgcaccgcc ccttccacgc cctgccgccg ggcagcacct gggaccgggt gccgggggcg
     6301 accctggttg gcgacgcggc ccacctcgcg gcgccgaacg gcgagggcgc caacctggcg
     6361 atgctcgacg gcgccgagct gggcgaggcc atcgccgcgc accccgacga cgtcgagacc
     6421 gcgttcgcgg agtacgagcg cgccatgttc ccgcgcagtg ccgacaccaa cgcgcggttc
     6481 gcgggcgagg ccgccgtcga ggacctgatc gccttcttcg gcaccgcgga ggtcgcgggc
     6541 tggggcggcc ggtgaccgac cacggcccga ggtggggctt cacgacccac ccgtccgagc
     6601 cgtcgccgtc cttcgtggac acgaccccgg cgcgtcagcg gcgatcgagg ccaccggacc
     6661 ccggtgactc cgcggacctg ccgctgtccg ggtgacgcgg ccttctccac cggcacatcg
     6721 acgaacttcg aagaaggggg aactcccatg cacgacgtac tggtcgtggg cgcgggcccg
     6781 gtcggcctgt tcctcgcctg cgagctgggc ctcgcgggct gctccgtcct ggtgctcgaa
     6841 cgcgagcccg agcccaccac cccgtggagg gcctacccgt tggggatgcg gggcctgtcc
     6901 gccgggtcgg tcgaggcttt ccaccgccgc gggatgctgc cgcggctgct gacggcgtcg
     6961 ggcggcaacg ccgctcccgg caccgacctc gacgtcgagt cggccgccgc cgaggacgag
     7021 gcaccgccgc cccgcagtgc gggccacttc ggtgggatga tgctcgaccc ggccgacgtc
     7081 gacgtcgaca gcctgccgtt ccggctcccc ggccccgcgc tggagggcgt gatgaccagc
     7141 ctggaggcgg tcgagtccgt gctggccgag cgggccgcga agctcggcgt ggagatcagg
     7201 cgcggcgtgg ccgtctcggc cgtcacccag gacgacgagg gcgtcatcgc gcacgacggt
     7261 gagcacgagc acgcggcgcg ctggctcgtc ggctgcgacg gcgggcgcag cgcggtgcgg
     7321 ggtctggcgg gcttcgactt cgtcggcacc gacccgatgt tcaccggcta cgtcatgcac
     7381 gccgactccc ccgacgccga gcggctgcgc caggggttca cgctgacccc gaggggcatg
     7441 tacctgcgga tgccattccc agggcacctc gccgtgcagg acttcgacgg cggcgcctac
     7501 gaccggtcgc ggccgccgac ccgcgagcac ctccaggagg tcatgcgccg ggtgtccggt
     7561 gtggacgtga cgctggacgg gatccgcctc gcctcgacgt tcaccgaccg ggcgatgcag
     7621 accaccacct accgcagggg acgcgtgctg ctcgcgggcg acgccgccca catccactcc
     7681 ccgttgggag gccaggggct caacctgggc atcggtgacg ccgtgaacct cgggtggaag
     7741 ctcgcggcca ccgtgcgagg cgacgccccc gacggcctcc tggacaccta caccgccgaa
     7801 cgccacccgg tcggcgcgcg ggtgctggac tggtcgcgcg cccaggtggc cgccatcgcg
     7861 ccgggtcccc acaccccggc gctgctgggc gtgctgcgcg acctgctcgg gacccgcgac
     7921 gggacgacct acgtgcacga ccggctgtcc gggctgtcga tccgctacga cctcggcgag
     7981 gacgacccgc tggtcggccg caacgccccg gagttccggc tccgggaggg cacccgcttg
     8041 ggcgacctgc tccaggacgg ccggggcgtg gtgctcgact tcaccgccga ccaccgcctc
     8101 cgcgactcgg cggcgggctg ggaggaccgg atccggtacg tcgccggacc cgccaggaac
     8161 gacctcggcc acggcgccgt gctcgtccgc cccgacggcg tcgtcgcctg ggcgggtgac
     8221 cgcgagccgg accgggaggc gttcgggcgg gccgcccgcc ggtggttcgg cgagccggtg
     8281 tgagccaggg gcccgtccgc ggacgacgtg gacgggcccc gccgcgctac agccggaacc
     8341 cggcgggccc gcgcaccgcg gcggcggcca ggtcctccac ccgcgccgcg gacacgggca
     8401 cgccgggtgc tgcctggacc cacgccacga gctcgggcac ggagaggtcc gcgggcggcg
     8461 tgccgacgta gggcatgcag tagagcgggg tgttgggctc gccgcgccag ctgtccgcga
     8521 gcccgccgag gtccaccgcg tcgaagccga gggcgtccag cagcgccgcc acctccgcct
     8581 tggcggccgg gtcgtcgccg gacagcggca gcgcggtccg gtccggggcg ccggtcggga
     8641 ggcgcaggtc cagcagctgc ttcgggccga tcgagtggaa cgccttcacg acgcgcgagt
     8701 ccgccagatg gcgctgcacc agcccgctgg aggtcagctc gtcgccgtcc agctccgcgg
     8761 accgccacgc cggggtcggc acgtagttca tcgggtcgat gacggtcttg cccgccagct
     8821 ccgcgcgggg cagccgttcg tggacggaca gcggcacggc ggcgaggacg aggtcggcgg
     8881 cgcgcgccgc ctcggcgggg gtggccgcgc gggcctggtc gccgagcccg gcgatcaggg
     8941 cggtcagcgt ctccgggccg cgcgagttgg ccaggacgac ctccaggccc gcgtcgacgg
     9001 cgagccgggc gacccctgcg ccgaccgagc cggtgccgat gatgccgacg gttgttgtac
     9061 tcacgttcgg gttctccgtt cgggtggggc ttccgcccaa tcccatccgg agcggtccta
     9121 gccgacaacg gccgttccgg ctcggcagtg atcacatcgt gtgatagatc agaggagtgg
     9181 aactcagggc gctgcactac ttcgtgaccg tggccgagga gctgcacttc ggccgggccg
     9241 ccgagcggct gcggatcgtg cagcccgcgg tgagccagca gatcacccgg ctggagagcg
     9301 agctcggcgc gcgcctgttc gaccgcacct cacgccgggt gcggctcacc ccggccggtg
     9361 aacgggtgct cgtcacggcc cgcgcgaccc tggccgcggc ggcgcgcgtg cgggtggtcg
     9421 ccagggagtc ggccgcgtcc ctgcggatcg ggatggcgac ctgcttcacc ccgcgcgtcg
     9481 accgcgcgct cacccgcctg cgcgagggcg gacagctcgc cgagccgacc ctggtcgacc
     9541 tgccggtgcc cgcgcggctg gacgccgtcc gcgacggcga gctggacctg gcactggtcc
     9601 gcggcaccct cacgtccacc gcgatgacgg tcgtgcgcgc ctggtccgag cccgtccacg
     9661 tggtgctgtc ccgcgagcac cgcgccgcgg gcaagcccgc cgtcgggctg cacgacctcg
     9721 accccgacgg cctgcggctc ctcacccgcg cggccgaccc gccgatgcac gacgcggtgc
     9781 tggccgccct tccggaggca ccgcggcgcc cacccgtcgt ggacacgctc aacgtgctgg
     9841 tcgaggtggg ccaggacccg gagggctgga cgctgctgcc cgtcgagcag accaccgggt
     9901 ccgactccgc gcggctggtc caggtgccgc tcgacccgcc gctgagcgtc gacggctccg
     9961 tcgtgacgcc cctcgccacg cccgcggcgc gcgtggcgtc ctacgtggcg gcgttcgggg
    10021 actgagcgcc ctcctcgatc tcgtcccacc accaggcgat accggggatg ggcggcgcgg
    10081 tcgggtccgc gtcggacggc acgtcggccc acggcgagga cgtccgctcg ccgtgctccg
    10141 cgcggcggta gcgcgggacg cgggcgctcc actccaggtt cccgcggacg aggtggtcga
    10201 gctggctcag gtgccgccgc accgggtcgc cgccccgtgc cccgatccga cggcgcagcc
    10261 gcaggtaccg gcacatgatc cggtcgtgca aggctacggc gcgccggacc gcctccggcg
    10321 cgtcgcagcc gtcctcgtgc ccgatcacgc cgacgatgtt ggactccagc acgtcgtgct
    10381 cggtctcctt cgacagcgag tacaggtcgt tgccgatcgt gacgagcatg ttggccgcct
    10441 gcgtggcggc gcggacctcg ggccgttcac ggtcctcgtc gggcaggtaa gtgccctccg
    10501 cgatctcgat cagcgacccg gtcagcctca tcgcgcggtc gcggggaccg aggttgacgt
    10561 agtcggcgag cgacggcatc gacccggaga cccggtagga ggtcaggcag gcgaccgcga
    10621 agaaccactc catgttgccc tcgacccacc ggcggaccac cgcggcgggc acggcggccc
    10681 gcgcgcgggc ggacaggtcg cggaacccgg ccgagaacgg gtcgtcggcg gccacctccg
    10741 ggtggtccag gttgggcatc agccgcatca tcagcgggat caggaccccc ggccgctcga
    10801 ccagcgcgcc cgcgtcgaac ctgcagtcgt cgatggcgaa acccaggtgc gtccagtccg
    10861 agacgatctg cagccgctcc tcgctgccga agggcgcgat ccggcacgcc cactccgcgg
    10921 cgcgggtgcg gatcatgtgc tcccgcaggc cttcctgctc gaacagcccc agcccgtcca
    10981 gccaggcgat gctgcgccgt ccgatgtcgg cggcgagcgg gtgcacggcg gaggggagcg
    11041 ggcagtagag gggcggcacc tccggcgcgg ccgtgcgcac ggcggtcatc ggccggtccc
    11101 gctcggggtc atgaccagcc ggtgggggtg gatggtcacc cgcggcaccg gtcgggggac
    11161 gacggcgggg tcggggacca tccgccacct cctggtcgtc tccgccagga tgatgaccat
    11221 ctcgctccag gcgaacgact cgcccacgca ctgccgcgcc ccgccgccga acggctggaa
    11281 cgccgtccgc gggatcgacc gcgcccgctc cggcgaccac cggtcggggt cgaaggccgc
    11341 gggatccggg tacaccacgg gatcgcggtg caggatgtac gggctgaaca cgacggtggc
    11401 gccctgcggc aggtcgaacc cgcccaggct ggcgggcgcc gtcacggtcc tggtcagcag
    11461 ccacgccggg ccgtagagcc gcatcgcctc gtgcaccacc cgccgggtgt aggtcagcga
    11521 cccgaggtcc gcgccgacca gcggccgtcc gggcgccacc tcgtcgagct cggcgacgat
    11581 ccggtcgcgg acggcggggt gacggccgat ctcgtgcagt gcccagagga cggtcgcggt
    11641 cgacgcctgg ccgttggtgg tcacgaacgt gatcacctcg tcctccagct ggcgcctgct
    11701 catcggctgc cccgtgtccg ggtcgcgggc gtccagcagc aggtcgagca accccttgtc
    11761 ccgcaagggg cgccggtgtt cgtcgacgag gtcgccgatg gcgtcgcgca gctccgtgaa
    11821 gctgtcgcgc tggcggcgtt gcgtcggtgt ggggaccgag ccgagccacg gcggcaggat
    11881 ggtcgcccgg atcgtccccg ccatcacgtc cggcagcacc cgctggatcc ggcgccgggt
    11941 cgcctcgggc ggttcggttc ccagcagcgc ggccaggaac accgacagcg tcagctcctg
    12001 catgtcgtcg tggagctcgc gcggctcgcc cgccgcccac ccgtccacga cggacctggc
    12061 gacctcgatc atggtgtcgc cgcggcccgc gatgaaggcc cggctgaaca tcggctgcac
    12121 cagcctgcgc tgggtgcggt gcaggtcgcc gtcggccacg gtcgccaagc cgttgcccgc
    12181 gaaccggctc agcgcctcga tcagcctgcc gcccttgccg aaggaggacg cctgcgcggt
    12241 cagcatctcg tgcgtgaggc ccgcgtcggt gacgacgaac accgggatgc ggccgagcat
    12301 gatccgcacg acggggccgt ggcggcgcag cgagtccatg aacgccaacg ggtgtctcaa
    12361 caggggcacg acgtgcccga gcagcggtgc gccgcccggc gcgagaggag gggcactggt
    12421 ggaggtggcg gtcgccttca tgaaccgggc tcctcactcg gcgccgtcca cccggccgtg
    12481 gggcgcggga ggtcagagcc gtgcttcggg gggtggtgcg aacgggccgc cgcgaacgta
    12541 agcgaggccg tcgcgggtcc gcaatgatct gtccggctga gcaggaatgc ccgttttcgc
    12601 tggtgggact gggttttcgg cacggcttcc cggtgctgcg ggcggcctgg cgagttcctg
    12661 ccacggatgt cgttgcgcca cggggctttc cctgctcggg ctggtgttgc gtcgagggca
    12721 agacggtgcg gtcaggccga ggtagaccgg gtggcgggcg cgactcccgg tcggtccggg
    12781 gtggcggtgg tggggctcgg ggcccgacgg ggtcccgcag cgtcctgatc gacgtccggc
    12841 gaacctgagt acagtcggat cggagatcac cagcggaggt cgacatgaag aagaacatca
    12901 gctgcccgtg cggtgagcgg atcaccggcg acgacgagga cgacctcgtg gcgaagaccc
    12961 agcagcacct caaggagaac caccccggcc acgactactc gcgcgacgag atcctgttca
    13021 tggcctactg agccgcgccc ggcgcgggct cagcgctgcg tggcgacgcg gacgaggtcg
    13081 gccagcgccc gcgagcggct gtgcggcggc caggcgatga cggtcgtgac cggcggcgcg
    13141 tccagcaccg gcaccgcggt gaggccttcg agcaggttgg cgcggcagga gtcggggagc
    13201 accacggtgg tgcggcccag tgcgatcagc tggaacagct gcgtctggtt gtgcacctcc
    13261 gcgccggggc cctccgggta gctgccgtcg gcgcggggcc agcgggcgag cggcaggtcc
    13321 ggcagcgcgc tgacgtcggc cgtccgcaga tgcgacctgc tcgcgagcgg gtgcgaggtc
    13381 gggagcaccg cgacctggct ctcggtggtc aggatctcgg tgtccagatc ggccgtcgag
    13441 tcgaacggca ggtgcagcag cgccacgtcg gcgcgcccgt cgtgcagcgg ccgctggggt
    13501 tgggattcgc acagcagcag gtcgacggcg accgcgtccg gttcggcggc gtaggcgtcg
    13561 agcagcttcg ccagcagctc gccggaagcg cccgccttgg tggccaggac caacgacggc
    13621 ctgctggtcg cggcctgctg ggtccgccgt tcggtggcgg ccagcgcgcc gaggatcgcg
    13681 cggccctcgg tcagcagcac ggacccggcc tcggtcaacg agaccttgcg gctggtgcgt
    13741 tccagcagcg cgaccccgag ccggtgttcg agctgggcga tcgtccgcga caacggcggc
    13801 tgggcgatgc ccagccgttg ggccgcccga ccgaagtgca gctcctcggc gaccgcgacg
    13861 aagtaccgca actcccgcgt ctccacgggt ttcagcctac ccgcggatcg atatccgcag
    13921 ggtatcgtcg caccacccag acggtgttgg tgtcccgtcg gtgcgcggtc acgatcgagt
    13981 catgagtgag cggacgatcg cgttggtcac cggcgcgaac aaggggatcg ggtacgagat
    14041 cgcggcgggg ctgggcgcgc tggggtggag cgtcggggtc ggggcgcggg acgggcagcg
    14101 gcgcgatgac gccgtggaga agctgcgcgc ggcgggggtg gacgcgttcg gcgtgccgct
    14161 ggacgtgacc gatgacgcga gcgtggctgc cgccgcggcg ttggtggagg agcgtgccgg
    14221 gcggttggac gtgctggtga acaacgcggg tgtcgcgggg ccgtggcccg ctgtgccgtc
    14281 gacgatgtcg gtggacgcgg tgcgggacgt ggtggagacg aacgtgctcg gcgtgatccg
    14341 ggtgaccaac gcgatgttgc cgctgctgcg gcgctccggg agcccgcgga ttgtgaacca
    14401 gtcgagccat gtggggtcgt tggcgttgca gaccgcgcct ggtgtggagc tcggtggggt
    14461 ggacggggtg tattcgccga cgaagacgtt cctcaacgcg gtgaccgttc agtacgccaa
    14521 ggagctggtg ggggtgaagg tcaactgtgc ttgtcctggg tatgtggcga cggagttgaa
    14581 cggctttcgt gggaccagtg cggcggagga gggggctcgg gtggcgatcc ggttggcgac
    14641 tttgccggat gacgggccga gtggggggtt gttcgatggt gcgggggttg tggcttggta
    14701 gggggtgctg gtgcctcggg cggctgtggg gatttgctgt gttgtctcgc ccggtgtcgc
    14761 tacagcggac ctaggtgcgg tcggcttgac ttggggcccc ttttttgggc ttcgtcgggc
    14821 gaaaaagggc aggtggtaga gcctgcccgc cgccgcaagt ctaagcccaa aaaccccaag
    14881 tcaagccgac cgcacgagcg gacgagcgtg ctcgcttcca gcatcgctgg gtgacttgtc
    14941 tgctgcttcc agcatcgttg ggtagctggc tggctgtttc ggcgtcactg gcagtctgct
    15001 tgcttccggc gtcgctgggt cagcttgtga tcgatacgcc gtggtcattt ccggtgtcgt
    15061 tgggtcattc gcctgctgct tctggctttg gtggtgctgc ttgtcctgac gctactatgt
    15121 tggtcagcac agtgacggca ggccagcaca gaggtgtgtt gggggagagg tggggttgtg
    15181 agggagtggg acggggcggt tgcgttcatc accggtgggg cccaggggat tgggctgggg
    15241 attgcgcgtg cgttggggaa gcggggggtg cggttggcgg tggttgacat cgacgaggag
    15301 gcgttggggc ggtgtgggga tgagctgggt gaggtggggg aggttgaggt ttatcggttg
    15361 gacgtgcgtg atcgggcggc gttcgcctcg gtggccgacg aggtcgaggg gaggttcggg
    15421 ggtgttgatc tgttgttcaa caacgctggg gttgtgccct actcggcggt gtcggagttg
    15481 gggtacgaga agtgggatct ggcgttgggg atcaacgtcg tcggggtggt gaacgggatc
    15541 cagacgttcc tgccgcgcat gatcgggcgg gggcggggtg ggtacgtggt gaacacggcg
    15601 tcgggggcgg ggttggtcgc ggatgcgaac gtgttgtacg tgacgacgaa gttcgcggtg
    15661 gtggggttgt cggagtcgct gcggttggcg ttggaggggc acgggatcga cgtcagcgtg
    15721 ctgtgccccg gtccggtcga caccggcatc gtgcgcaaca cgcgggcgtt ggacgagagt
    15781 gcgttcacgg ggttgagcga cagtgccgtg cagggtgtgg aggcgttcct caagagcggt
    15841 gtgagcatcg acgaggtggg tgagatggtc gtcgcgggca tggaggcgcg gtcggcgtgg
    15901 atccacaccg acgccgtggt gcgaacccac gtggagcagc ggatgacggc catcctggac
    15961 tccatcccgg ttccggcggc cgggacgccc tagtcggcgc gcttgcgggc cttccggtcg
    16021 ttcgcggtgc ggcggtgcgg ggtgagcggg gtggtccaca cgtcggccag gttcttgtcg
    16081 accatggccg agatcgacct cagggccgcg tcgaggtcga agccgtcggg gtcgatgagg
    16141 gcctggaggt ggatgccgac gagcgtcccg tggagcgcga cggcgaacgc gcgctcctgc
    16201 ttcgcggcgg tctcggggtc cgcgccctcg ggccgctgca cgcgcagcca cagctcgagc
    16261 ccgtcccgcc gccgggcgaa gaagtcctgg tactgcgcgt ggacgacacc cgtggtgccg
    16321 atggcctcgg tcaggatcat gaacggcagt cccgcgttgc cctcgcgcac caaggtggcg
    16381 gagtcctcga acacctcggt gagcgggggc acggacttgt agaggcccgg cggcatggcg
    16441 cggtcgatcg cgcgttccag gaccgccacc acgagaccgg ccttgttctt gaagtgccag
    16501 gggatcgagc cgcggctgat gcccgagcgc tcggcgatgt ccacgaagga cgtgcggtcg
    16561 aagccgcgct cggcgaacag ctcctcggcc gcgtcgagga tgcgacggcg gctctcgtcg
    16621 ccgatctcgt cgatccggcg ctgacctcgg gcactcacgg tggtcatcct agatcgacgt
    16681 ccggccgccg cccggtccgc acgggcgaat agttcgaaca ttgactgtta gaggcctaac
    16741 ggttagagtt ctcatcatgg acgcacccga gctcaccacc agtctcgacc tggtccgttg
    16801 ggtcgtgtgg gcccagcgca aggcggggga ggactggatc cgcgagcgcg ggctcagcca
    16861 cgagcagagc ttcgtgctcg gatacctggt ccagagcccc ggtgcgatcc agcgcgacat
    16921 cgcggagatg acgcgcacga gcgcggcgag cgtctccagc ctggtgcagg gactcgaacg
    16981 ccgcggcctg gtggagcgcc ggacggaggg cggggacgtg cgcagcaagc gcgtctacgc
    17041 cacccccgag ggcggtgagc tcatcgccgg gttcagcgcg gcgatggccg ccgtcgagga
    17101 gacgatcctg gccccgctgg accaggacga gcggaccacc ctgcacgccc tgctcacgaa
    17161 gatcaccgcg gagctgcccc ggcccacccg gtcgtaaccg ccggccgcac ggaccgaact
    17221 cccctcaacg ccacgcccgc cccccgcggg cgtgcactcg aacctgcccg aacggagtca
    17281 ccatgaccag ccacgtcacg atcatcggtg ccggactcgg cggcctcacc ctggcccgcg
    17341 tcctgcacgt ccacggcatc ccgtccaccg tctacgaggc cgaggcctcg cccaccgccc
    17401 gtgcgcaggg cgggatgctc gacatccacg accacaacgg ccaacccgcg ttggaggcgg
    17461 cgggcctgtc cgaggagttc cgcgcgctcg tgctggaggg ccgccaggcg atccgggtcc
    17521 tcgaccggga cgggaacctc ctgttcgaca aggccgatga cggcacaggc gggcgtcccg
    17581 aggtgcagcg cggcgagctg cgccgactgc tgctcgactc gctgccggag ggcaccgtcc
    17641 actggggacg caaggtgggc ggtgtccggg cgctcgggga cgggcggcac gaggtgacct
    17701 tcgacgacgg cgacaccgtc gtcgcggagc tgctggtcgg cgcggacggc gcgtggtcgc
    17761 gggtgcggcc gctgctgtcc gacgcggtgc ccgagtacat cggcaggtcg ttcgtcgaga
    17821 cccacctcca cgacggcgac acccggcacc ccgccgcggc gaaggcggtc ggcggcgggt
    17881 cgctgttcgc cctggcgccg ggcaagggga tccaggcgca ccgggagagc ggcgacaccc
    17941 tgcacaccta cgtggcgctg tgcgagtcgc aggagtggtt cgcgggcatc gacttcaccg
    18001 acgccgacgc ggccaccgcg cggatcgcgg cggagttcga cggctgggcg cccgagctga
    18061 ccgcgctcat caccgagagc gacacgccgc cggtcctgcg cccgctccac tcgttgccga
    18121 tcgggcacag gtgggaacgg gtgcccggtg tcaccctcgt cggcgacgcc gcgcacctgt
    18181 cgggtccgaa cggcgaaggc gcgaacctgg caatgtacga cggcgccgag ctcggcaagg
    18241 ccatcgcggc ccacccggac gacgtcgagg cggcgctcgc ggagtacgag caggacctgt
    18301 tcccccgtgg tgccgaagcc gcggcggacg gcgttcagct ccacgagttc ctgttcggcg
    18361 ccaacgcacc gcacagcctc gtcgacgcct tcctggccga cgacgagacc tccggaggac
    18421 ggctgtcctc agtggactga ccgactaccg cgccggatgt cgacgacctc tcccaagagc
    18481 ttcggcgggc ggagcgcgac cttccggccc caggcctggc acggtacctc gatgaagcgg
    18541 tgggtcacca cgcacagcgg cagcagcacg gcgtagaaag ccagctccag caccaagttg
    18601 tcctgccgcg accggccgaa ggtgccgtcg tgcacggcca gcagcagcgg gtgcacgagg
    18661 tagaccgagt agctgatcgc ccccaacccg gtgagccagc gcggaacccg tcggtggcgg
    18721 gacgccagac cgaccccgaa ggtgagcagg gccagcagga acgccacgat ccagccgcgg
    18781 cgggtgaagt gcgggtcgtc accgtgcagg taggcgctgc ccacggcgca gacgaccacc
    18841 acggcggccg cgcaggccgc gtaccgccag gtgctccgac cgctctcggc ccggtggacg
    18901 gccgtgccga ggaacatcac ggcgaggatg accagccctt cccacaccgg gaccgttccg
    18961 ttgagcagca ccagggtcag cccgagcacc ccgcccagca cacccccgaa cacccgcagg
    19021 gcggacgacc ccgagcacgc gcagccgatg gccaccgcca tcgtgaccga ggtcagcgcg
    19081 accagcgggc cggtgccgac cacgtgggag agcatggaca ccggcagcac gacccccgcc
    19141 gccacgctca cggcggcgag cacggccaac gtgatcgcga cggcaccgga acgctggtgc
    19201 tggcggacgg tgaagagcgc caccaccaag aggtagaagg ccatctcgta ggagagggtc
    19261 cacaggacga gcaggaggtt gtgcgttccc agcagttcct ggaacagggt gaggtgggcg
    19321 acggccaagg cggcgttgtc ctgcccgccg cggatctccg tcagcccggc caggcccgcg
    19381 accacgaccg cgccgacggc gaccgcgcac agcgggtaga tgcggaacgc ccggccgatc
    19441 cagaacgccc ggacgtcacc gcggcgttcc agcgaggccg ggatgatgta accgctcacc
    19501 aggaagaaca ccatgatgcc gaaccggccg atgttgaacg tcggcatcag ctcccgttgc
    19561 agctcgggct ggaacgagga cgacgagtgg gcgaacgcca cgacgagcgc cgcgatgccg
    19621 cgcaacgcgt ccagccaccc cagccgcgac gcgcggtgcg gtgtcgcggc gaccggtggt
    19681 cgggggatgg tggagatcgg gcgcagggtc gggagaacgg gctccatgca gttcgtcacg
    19741 cgcccgccgc cgccgaggtt gcctggcgct ccggtcagtc ctcccggcgc ccggtcacgg
    19801 gcggacccag cggtggtagg cgtccaggtc gacgttgcca ccgcagacga tcgtcacgac
    19861 gtggcggccc gcgaaccgct cgcggtcctc cagcaccgcg gccacgccga gcgcggccga
    19921 cggctcgacg accagacccg tgtgctccag cagcaggcgc atgccctcga tgatcgacga
    19981 ctcgcggacg agcacggcgt cgtcggtcac cgcgaggagg tcgtccagca cctccgggat
    20041 ggggaagcgg cccgcgacgc cgtcggcgat ggtgtcgagg gagtcggtgg tgacgacgcg
    20101 ccgctcgtgc cacgaccggg tcatcgcggg cgctcccgcc ggctgcacgc agatcacctc
    20161 cacgcccggc gccacggtct tgaggacgtg gcccacgccg ctggccatcg cgccaccgcc
    20221 gagtgcgacc aggaccgcgt cgaacgcggg gcccgcgccc gccagttcga gtccgatggt
    20281 cgccgcgccc tcgcaggtct cgacgtccag gctgtcctcc agcagtcgga tcccgcgctg
    20341 tcgcgcgatg tccgccgccc gagcgcgggc gacctcgatg tcgccgtcga ccagttccag
    20401 ctccgcgccc agcgcgcgga tccggtcgag cttggtggcg ggcgcccgct tcgacgccac
    20461 gaccgcgacg tcgaggcctc ggcgcaggcc cgaccagctc agcgcctggc cgaggttgcc
    20521 cgcgctggcg cacaccacgg cggtccggcc ctgctcgacc agcaggctcg tcacgagctc
    20581 ggtgcccctg gccttgaagc tgcggaccgg gttcgccgtc tccagcttca cgctgacggt
    20641 gcacccgagc tgcctgccga gcgcgtcgca cgggtagagc ggggtgtcga ggaacatcgg
    20701 gtcgacgacc cggcgggccg cgtggatccg gtcgaggtcg aggcgcgtct ggggcacgcc
    20761 gggaccttat ccgtcctcgg tggtcagcca accggctcgc gcacgggtgt gccggtccac
    20821 cggtgcaggg cgtccgcgag ccccgcgctg tcggtggtgt cgcaggccca ggcgaccacg
    20881 ccgtccgggc gcaccaggac gccggtcggc gtcgcgtggt cgtcggtcac ggtggtcacc
    20941 cgcccggccc aggccgtggc gaggcgggcg aacccgccgt ccggggtgcg gtcgagcagc
    21001 aggaacccgc cgccgtggcc gtggtcggcc agccgggagc cgtcggcgag ccacaggtcg
    21061 ggggcgtgcc tgccgaccag cgggtggtc
//
