LOCUS       NZ_PVTF01000006        20960 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Umezawaea tangerina strain DSM 44720 Ga0180964_106, whole genome
            shotgun sequence.
ACCESSION   NZ_PVTF01000006
VERSION     NZ_PVTF01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Umezawaea tangerina
  ORGANISM  Umezawaea tangerina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Umezawaea.
REFERENCE   1  (bases 1 to 646484)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 646484)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Expected Final Version            :: No
            Genome Coverage                   :: 86.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003002815.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:47:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,483
            CDSs (total)                      :: 9,418
            Genes (coding)                    :: 9,322
            CDSs (with protein)               :: 9,322
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 20 of 97
            Pseudo Genes (incomplete)         :: 83 of 97
            Pseudo Genes (internal stop)      :: 2 of 97
            Pseudo Genes (multiple problems)  :: 8 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 447530
            Orig. end                         :: 468490
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVTF01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20960
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20960
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20960
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10960](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10960)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            300..758
                     /locus_tag="CLV43_RS22280"
                     /old_locus_tag="CLV43_106388"
     CDS             300..758
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017982288.1"
                     /locus_tag="CLV43_RS22280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106388"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_106189167.1"
                     /transl_table=11
                     /translation="MSLAEDATEARAQGWRTLAALHARIEDKLERALQRAHDLSVSEYT
                     VLDVLARQDDFHLRMSQVSQAVVLSQSATTRLVTRLEDRGLLGRYLCATDRRGIYTELT
                     PAGVALLDAARPTHDAALGEALAEAERLPELAPLVTALAGLPASSTSR"
     gene            804..1268
                     /locus_tag="CLV43_RS22285"
                     /old_locus_tag="CLV43_106389"
     CDS             804..1268
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100038.1"
                     /locus_tag="CLV43_RS22285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106389"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_245886803.1"
                     /transl_table=11
                     /translation="MRNLEQLDAADVTFVIRVTAPQASRVANRVADALKAALGQAAVDV
                     EVPVRRGGPALRVFPESRRVLHRGEAVELTRLEFDLLLHLCSQPRRVHRRAALMHQVWG
                     ATTVVDTRTVDVHVRRIRRKLGDAAGVIGTVRGVGYRVDQEHQVRVERED"
     gene            complement(1341..1787)
                     /locus_tag="CLV43_RS22290"
                     /old_locus_tag="CLV43_106390"
     CDS             complement(1341..1787)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016330823.1"
                     /locus_tag="CLV43_RS22290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106390"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_106189168.1"
                     /transl_table=11
                     /translation="MSTAAETTLSIGQVSALTGLTTHTLRFYEQEGLFVAPVRRNAAGR
                     RVFTTEEVEWLKVCTKLRSSGMPLPEIRRYAGLVLAGPGNEVERFDILRRHEANVQQQV
                     DDLQEALTVIHRKVELYARRLDEGTADQLWTNGPECDPLPDAAE"
     gene            1865..2692
                     /locus_tag="CLV43_RS22295"
                     /old_locus_tag="CLV43_106391"
     CDS             1865..2692
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (3-116). E-value: 1.4e-08. Score:
                     26.8. Matches aSDomain:
                     nrpspksdomains_CLV43_RS22295_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803756.1"
                     /locus_tag="CLV43_RS22295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106391"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_106189169.1"
                     /transl_table=11
                     /translation="MPSTWFITGTSTGFGRLLVEELLGRGDRVAATLRKPEALDDLQAE
                     HGDRLWVGRLDVTDTEQVRKVVDDAFQELGTIDVVVNNAGHGVFASVEEATDEQIRQVV
                     DTNLMGSIHVIRAALPHLRAQGRGRILQVSTAGGQATYPNFGYYHASKWGIEGFCETVA
                     REIAPFGIGLTIVEPGATPTGFGGSLATAPIMPEYENTPAGDVRRALADGSFTLPNDPR
                     KIAKAMIELVDTGAVPLRLPLGSDTYRDVRAALVARLAEHDEHREVALSVERD"
     aSDomain        1874..2212
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLV43_RS22295_PKS_KR.1"
                     /evalue="1.40E-08"
                     /label="CLV43_RS22295_PKS_KR.1"
                     /locus_tag="CLV43_RS22295"
                     /protein_end="116"
                     /protein_start="3"
                     /score="26.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TWFITGTSTGFGRLLVEELLGRGDRVAATLRKPEALDDLQAEHGD
                     RLWVGRLDVTDTEQVRKVVDDAFQELGTIDVVVNNAGHGVFASVEEATDEQIRQVVDTN
                     LMGSIHVIR"
     gene            complement(2696..3049)
                     /locus_tag="CLV43_RS22300"
                     /old_locus_tag="CLV43_106392"
     CDS             complement(2696..3049)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.4"
                     /locus_tag="CLV43_RS22300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106392"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_170155964.1"
                     /transl_table=11
                     /translation="MPTDIQGSLVVQRWRLAGATVVSVSGEIDIATVRKLRWSLDSVAS
                     GSGPLVLDLSSVTFFGSVGVDCLLETARRAHAFRIDLRLIRSPEVSRLLDLLGVRDEFT
                     EFDSLSSALAHSA"
     gene            complement(3169..3684)
                     /locus_tag="CLV43_RS22305"
                     /old_locus_tag="CLV43_106393"
     CDS             complement(3169..3684)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005460249.1"
                     /locus_tag="CLV43_RS22305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106393"
                     /product="DUF6328 family protein"
                     /protein_id="WP_106189171.1"
                     /transl_table=11
                     /translation="MSEAEESEQERLKRNLNELLQELRVAQAGVQILFGFLLSIVFTDR
                     YQDIDRYVRVTHLVTILFAACSVALLTAPAAWHRMLFRRGRREDIITIAHRFTVVGLGT
                     LAAAMTGTVLLLGEVIVGGWVAILFGVVAGVGFTTLWFLLPLMQRHRDTIDSEGHPDGV
                     PTGEPSHE"
     gene            complement(3740..4312)
                     /locus_tag="CLV43_RS22310"
                     /old_locus_tag="CLV43_106394"
     CDS             complement(3740..4312)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV43_RS22310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV43_106394"
                     /product="hypothetical protein"
                     /protein_id="WP_106189172.1"
                     /transl_table=11
                     /translation="MSDVDETRSAGPSALWAGPRDAPAVVVLDPAGVGRHGDLPATWQP
                     LVEHLQVLWCRLPAADGPWREVSDLLAEFEGRGVPVHLLTGGPAAASALYLADRYRGLV
                     RSVLLVDPEEGPDRTTGQQADVRVVVRESLPLGHPDVVVAVVRALLELDADDAHAPRKP
                     SPPSLLGDAATALRESVTSILDRVRRA"
     gene            complement(4322..>4467)
                     /locus_tag="CLV43_RS49380"
                     /pseudo=""
     CDS             complement(4322..>4467)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667062.1"
                     /locus_tag="CLV43_RS49380"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="metallophosphoesterase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LAVHGHAHFGIGHGVRPGGVRVRNVAQPSVTPTGCTRSNRWLKRP
                     QPG"
     misc_feature    complement(4342..4344)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4422..4559)
                     /locus_tag="CLV43_RS47895"
                     /old_locus_tag="CLV43_106395"
     CDS             complement(4422..4559)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV43_RS47895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV43_106395"
                     /product="hypothetical protein"
                     /protein_id="WP_170155965.1"
                     /transl_table=11
                     /translation="MRAGLIAAVGDVHLGKDARGPALENVGNHADWPSTGTRTSASGTA
                     "
     gene            complement(4705..5721)
                     /locus_tag="CLV43_RS22320"
                     /old_locus_tag="CLV43_106396"
     CDS             complement(4705..5721)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (55-224). E-value:
                     3.4e-12. Score: 37.9. Matches aSDomain:
                     nrpspksdomains_CLV43_RS22320_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102449.1"
                     /locus_tag="CLV43_RS22320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106396"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_106189173.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2e-06, bitscore:
                     22.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVVVTGASGNVGTALLRALPPEVEVTAVARRVPASGPPYSRADW
                     AAVDIGMPGAEEPLADLMLGADAVVHLAWLIQPSQDERALHRTNVMGSKRVFAAAVGAR
                     VPHLVHMSSVGAYTRADKTRRVDERWPVGGIPSSSYSRHKSTVERLLDEVRRDNPYLTT
                     SRLRPGLIMQADAASEIKRFFLGPLIRPGLLRMAVSGRIPVLPLPSGLVLQFVHADDVA
                     EAVVRVLETRLPGAVNIAAEPVIGPRDLAELVGARHVPVPASAFRGLATATWRLHAQPT
                     SPGWVDLALGAPILSTDRARTELGWKPTRNAREVVRELLAGMGEQDGLPQSPPLAPE"
     aSDomain        complement(5050..5556)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLV43_RS22320_NAD_binding_4.1"
                     /evalue="3.40E-12"
                     /label="CLV43_RS22320_NAD_binding_4.1"
                     /locus_tag="CLV43_RS22320"
                     /protein_end="224"
                     /protein_start="55"
                     /score="37.9"
                     /tool="antismash"
                     /translation="EEPLADLMLGADAVVHLAWLIQPSQDERALHRTNVMGSKRVFAAA
                     VGARVPHLVHMSSVGAYTRADKTRRVDERWPVGGIPSSSYSRHKSTVERLLDEVRRDNP
                     YLTTSRLRPGLIMQADAASEIKRFFLGPLIRPGLLRMAVSGRIPVLPLPSGLVLQFVHA
                     DDVAEA"
     gene            complement(5740..5910)
                     /locus_tag="CLV43_RS47900"
                     /old_locus_tag="CLV43_106397"
     CDS             complement(5740..5910)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV43_RS47900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV43_106397"
                     /product="hypothetical protein"
                     /protein_id="WP_170155966.1"
                     /transl_table=11
                     /translation="MEIVRRTDPTTTGEARFGGHGMWAPMIPIARDPDEWVCWVGDPDE
                     GLDPVVVRSVD"
     gene            complement(6019..7413)
                     /gene="xylB"
                     /locus_tag="CLV43_RS22325"
                     /old_locus_tag="CLV43_106398"
     CDS             complement(6019..7413)
                     /EC_number="2.7.1.17"
                     /GO_function="GO:0004856 - xylulokinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_process="GO:0005997 - xylulose metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="xylB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210: glycerol kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800633.1"
                     /locus_tag="CLV43_RS22325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106398"
                     /product="xylulokinase"
                     /protein_id="WP_211304473.1"
                     /transl_table=11
                     /translation="MLVAGIDSSTQSCKVVVRDAETGALVREGRASHPTGTEVDPAAWW
                     TALGEAVEAAGGLDDVAGVSVAAQQHGMVCLDADGEVVRPALLWNDTRSAAAATALTGE
                     LGGPQEWARAVGSVPVAALTVTKLRWLAEHEPDNAARVAAVCLPHDWLTWKLAGAPGLE
                     ALVTDRSDVSGTGYWSPSTGEYRLDLLDLALGKRPVLPRVVGPADHAGTTAGGAVLGAG
                     AGDNAGAALGVQVGPGDVIVSIGTSGTAFARSPHPSADVSGLVSGFADAEGTFLPLVCT
                     LNASRVLDATARVLGVDLAELSRLALSIPDTGGLVLVPYLEGERTPNKPDSTGALHGLR
                     LDTATPAHFARAAVEGMLCSLADAIDALAAVGTPISRVLLIGGGAQSPAVREIAPAVFG
                     CPVLVPAPGEYVADGAARQAAWAVSGAEAPPHWGEALSTTSYEADSTPAVRAAYAAARD
                     LTVSRS"
     gene            complement(7416..8585)
                     /gene="xylA"
                     /locus_tag="CLV43_RS22330"
                     /old_locus_tag="CLV43_106399"
     CDS             complement(7416..8585)
                     /EC_number="5.3.1.5"
                     /GO_function="GO:0009045 - xylose isomerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="xylA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029545.1"
                     /locus_tag="CLV43_RS22330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106399"
                     /product="xylose isomerase"
                     /protein_id="WP_106189175.1"
                     /transl_table=11
                     /translation="MAEQPTRADRFSFGLWTVGWRAQDPFGEATRPALDPVHAVHKLAE
                     LGAWGVTFHDDDLVPFGTESGERDKRISLFKDALEETGVTVPMVTTNLFTHPVFKDGGF
                     TSNDRGVRRYALRKVLRNLDLAAELGAKTFVLWGGREGSETDAAKDVRFALDRYREALD
                     TLAQYSIDQGYDIRFALEPKPNEPRGDILLPTIGHALAFISTLEHHELVGVNPEVGHEQ
                     MAGLNFVHGISQALWQGKLFHIDLNGQHGPRFDQDLIFGHGDVLSAFFLVDLLENGGYD
                     GPRHFDYKPLRTEDMDGVWSSAAANMRTYLLLKERAASFRADPEVQEALAAAKVAELGL
                     PTLSRGETARDLLADRSAFEDFDVDAAGAQGYGFVHLSQLALEHLLGAR"
     misc_feature    complement(8639..8650)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.84"
                     /tool="antismash"
     gene            8681..9889
                     /locus_tag="CLV43_RS22335"
                     /old_locus_tag="CLV43_106400"
     CDS             8681..9889
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100026.1"
                     /locus_tag="CLV43_RS22335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106400"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_106189176.1"
                     /transl_table=11
                     /translation="MSPPRPAGQHTVRRHNSALVLNAIADLSGHSRAEIAARTGLTKAT
                     VSSLVDRMIGANLVVEGAAAVRTGPGRRGTALFLAPDGPHGLGVEIGVDYLATCLIDLT
                     GEVRARWIQSADNRVLSPARVLSRVTKAVRTALAEADRMGVRVGGMGVAVPGLVESATG
                     ILRVAPNLGWREVDVRGELRRRADLDDIPVLVGNEANFAALAELWQGTGPRDFVHVSGE
                     IGIGAGIVVDGGLFEGVSGFGGEIGHVMVDPRGPECACGARGCLERLAGQEEIYRQAGV
                     LDDRAPEELITDLLDRLAHRDRRSVAATRSAARWLGIALSGVVNLLDLPTVVLGGTYAR
                     LAPWLWEPLRDELAQRVVSSTWSPVEVTASTLGSEAAVRGAAGSAVRAILADPDPYVTA
                     ALA"
     gene            complement(10001..10960)
                     /locus_tag="CLV43_RS22340"
                     /old_locus_tag="CLV43_106401"
     CDS             complement(10001..10960)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="CLV43_RS22340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106401"
                     /product="terpene synthase family protein"
                     /protein_id="WP_146174869.1"
                     /sec_met_domain="T1TS (E-value: 3e-54, bitscore: 180.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVGAFTLSGLDVPGSRAEISPPFVLCAFDTESNAVDGLVTDHSV
                     GWAVSVGLLPPHAMNEAAGKELGHLVGYGYPRADYEQLRLMGDWALFAALLHEDGVSDQ
                     DLALLLAVLRDEPVPPGDPRVGAMADLRARLLALGGPEWVDGFAAEVGRMFDAISRSAL
                     DDHLGAVPTPEAHAEVCELTVGLHPMFHFAGPVDGVDLPRPVREHSALRELAATACRIV
                     GYARDLYTHRAEIARGGVHNLVLVTMRAQSVVLDQAVDRAVEIHDEEVRDFTRKAAELP
                     SFGPPVDEQVRGYVALLRRWVGGHRKWAEYTGSYRESG"
     gene            11151..13907
                     /locus_tag="CLV43_RS22345"
                     /old_locus_tag="CLV43_106402"
     CDS             11151..13907
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1173: WD-40
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100025.1"
                     /locus_tag="CLV43_RS22345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106402"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_106189178.1"
                     /transl_table=11
                     /translation="MPRGERPLDEGDTPLLRFAADLRTLRDQAGGRTYRQLGTRAHYSA
                     TTLSDAAGGRKLPSLAVTLAYVQACDGDPGEWEDRWREVAAEVAPAEARRADEGTPPYA
                     GLAAFQPEDAPWFFGRERMLDDLVARMSERRLVGVFGASGAGKSSLLRAGLVPRIAEGG
                     LDDGSCRTTIVVTPSELDLSADVLDRVVGAGVDELVLVVDQFEEVFTLCGDLAARTAFV
                     EALLSASRTRCRVVIGIRADFYGHCALHPGLVEALSDAQLLLGPLSAEELRQVIMRPAV
                     KAGCTVETALVTRLVADATGQPGVLPLVSHALLETWRRRRGTALTLAGYEAAGGIQHAL
                     TQTAERTFTALETDQRAVARQIFLRLTALGDGTEDTKRRLTRGELDADDVDTQVVLDRL
                     AHARLLTLDQDAVEIAHEVLIRSWPRLRGWLHENREGLRTARQLTEAAATWNLLSREPD
                     ALYRGTRLDTAVEWAAGGEARLSTREQEFLDASLADRDREQALALRRTRRLRQLVALLL
                     VLLLLAGGAIVQTIRAQDAADEQRNIAVAQQIAGAAVRMRESNRPLAQQLSVAAYRLES
                     TRDVVDGLLTTSAANWNKHLIRRVVPTTEVPMGPDGSAVRGKGQVPQQDSSGDLGSVQS
                     LGFTAAGRVLATTPDELWDLTDAGKPVSLHHFPNRMVATALSADGTRMATVDDSPDNTV
                     RLWELKRPEAPAFVSTVPHSGQGGREVRFDQSGQVLVTIDDDSTTTLWRLDRPDGPHEF
                     GRLTSIPHISTMALSQDRRLMATGGADGVIRLWDMADPWHPAKLVELGVQAAEVRALAF
                     SRDGRHLASAAGDQTVRLWDISDPRAPGEPATITGPTTSVHTAVFVQSDDGGDDVVVMT
                     SSGDGSSRRWDFDVARAVSRLCTGSTALTRADWDRFFPGFRFTPPCG"
     gene            14055..14366
                     /locus_tag="CLV43_RS22350"
                     /old_locus_tag="CLV43_106403"
     CDS             14055..14366
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017985336.1"
                     /locus_tag="CLV43_RS22350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106403"
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="WP_245886861.1"
                     /transl_table=11
                     /translation="MLPDTTDPAPVPTQPPASHVKLKPTRISGTWVAVIIAIFVLIFLL
                     VFILQNLAGVTIHFLGGAFTLPLGVALLFAAIGGALLVALVGAARIMQLRRQTKRALR"
     gene            complement(14383..14700)
                     /locus_tag="CLV43_RS22355"
                     /old_locus_tag="CLV43_106404"
     CDS             complement(14383..14700)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV43_RS22355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV43_106404"
                     /product="hypothetical protein"
                     /protein_id="WP_106189179.1"
                     /transl_table=11
                     /translation="MRRTGSTDGAGALRCRAVAELAGEDLRSGEVTMPLAPERTARVWE
                     AGRGGADDLTVREVAAELVACDAVQAFRDETLSHVDSAWTALEPLPPNTFAKVVCRALG
                     R"
     misc_feature    14723..14741
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.91"
                     /tool="antismash"
     misc_feature    14726..14739
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.9"
                     /tool="antismash"
     gene            complement(14751..15773)
                     /locus_tag="CLV43_RS22360"
                     /old_locus_tag="CLV43_106405"
     CDS             complement(14751..15773)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800626.1"
                     /locus_tag="CLV43_RS22360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106405"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_106189180.1"
                     /transl_table=11
                     /translation="MTEAARGRRLGARIEEVARQAGVSKSTVSRVINGEQYVSSRAREA
                     VLAAIVSLGYSPNQAARTLAGSRTNCIALVVSEQGSRVLSDPFFAGVLRGVHAELAGHR
                     VQLVLMMSQQDDEQDLVGYLCGGHVDGALVISLHGQDPLPQTLADAGLPIVVGGRPLGA
                     SGVPYVDADNFNGALEAARHLVTKGRKRIATIAGSKDMAVGMDRLSGWRRALSEFGMES
                     DLVAYGDFTPESGAAAMTELLARDPSIDGVFVAADIMALGALQSLHANGRRVPEDVAVV
                     GFDDLALASTAVPPLTTVKQDVEQLGRTMTWRLLAELAGEEGLPPSLLLPTSLVVRASA
                     "
     misc_feature    complement(15817..15826)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.85"
                     /tool="antismash"
     misc_feature    15824..15839
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.22"
                     /tool="antismash"
     gene            complement(15944..19534)
                     /gene="cobN"
                     /locus_tag="CLV43_RS22365"
                     /old_locus_tag="CLV43_106406"
     CDS             complement(15944..19534)
                     /EC_number="6.6.1.2"
                     /GO_function="GO:0051116 - cobaltochelatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobN"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1263: cobaltochelatase subunit CobN"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943736.1"
                     /locus_tag="CLV43_RS22365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106406"
                     /product="cobaltochelatase subunit CobN"
                     /protein_id="WP_106189181.1"
                     /transl_table=11
                     /translation="MILLLSTSDTDLLSARASGADYRLANPSRLEVADLPELVEGADVV
                     VVRILGGRRMWEEGLDAVLAGPRPVVVLGGEQNPDAPLMELSTVPGGVCAEAHAYLAHG
                     GAANLAELHNFLSDTILLTGNGFAPPVPAPNWGLLERPVPVTEGKTTDGPTVAVLYYRA
                     HHVAGNVAFVHALCDQVEAKGGRALPVYCSSLRTAEAELLAVLGTADALVVTVLAAGGS
                     KPATVGAGGEDEAWDVGALAALDVPILQGLCLTSSRAAWDDSDDGLSPLDTATQVAIPE
                     FDGRIITVPFSFKEIDEDGLTVYVADPERAARVAGIALAHARLRHTPPAERRIAVMLSA
                     YPTKHSRIGNAVGLDTPASVVRLLTALREQGYDIGAPGELPGVEQLDGDALIHALIAAG
                     GQDPDWLTEEQFTGNPVRMTAARYREFFATLPDDTRAEMEQHWGQAPGELFVDRSKDAD
                     GEIVLAALRAGNVVVMVQPPRGFGENPIAIYHDPDLPPSHHYLAAYRWLADDFGAHAVV
                     HVGKHGNLEWLPGKTVGMSAGCGTDAALGDLPLIYPFLVNDPGEGTQAKRRAHATLVDH
                     MVPPMARADSYGDIARLEQLLDEHGNIAAMDPAKLPAIRAQIWTLIQAAKLDHDLGLDD
                     RPHDAEFDEFILHVDGWLCEIKDVQIRDGLHVLGEAPTGDARVGLVLAMLQAKQMWAGQ
                     VAALPGLREALGLNEDGSETRVATDDVETTARALVQGMEDAGWAREAARGLTDSDQVAR
                     ILEFAADEIVPRLARTTDEMTNVLHALDGGYVPAGPSGSPLRGLVNVLPTGRNFYSVDP
                     KAIPSRLAWETGQAMADSLLARYRDETGEWPPSVGLSVWGTSAMRTSGDDIAEVFALMG
                     VRPVWDEQSRRVTGLEAVPLDELDRPRIDVTVRISGFFRDAFPHVVAMLDDAVQLVAAL
                     DEPAESNYVRAHAQADLATHGDARRATMRIFGSKPGAYGAGLLPLIDSRNWRDDADLAE
                     VYAVWGGYAYGRELDGVQARPDMESAYRRIAVAAKNIDTREHDIADSDDYFQYHGGMVA
                     TVRALTGKAPAAYVGDSTRPDAVRTRTLNEETTRVFRARVVNPRWLSAMRKHGYKGAFE
                     LAATVDYLFGYDATTGVVADWMYEKLAETYVLDPENRKFMTESNPWALHGISERLLEAA
                     NRGMWEHPEAETLAALQAVFLESEGDLEDR"
     regulatory      complement(19589..19656)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            19708..20733
                     /locus_tag="CLV43_RS22370"
                     /old_locus_tag="CLV43_106407"
     CDS             19708..20733
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100009.1"
                     /locus_tag="CLV43_RS22370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_106407"
                     /product="hypothetical protein"
                     /protein_id="WP_106189182.1"
                     /transl_table=11
                     /translation="MPTERTHADACPGAIDVHPAADGGLARIRVPGGTLTKVQFRAIVT
                     ASAELGDGQLELTSRANFQIRGLADGAQFELGDRMAEAGLLPSLTHERVRNIIAAPLSD
                     DTQAVVDALDRAICATPELADLPGRFLVTVGAEVAGLGADIGLVDDALLLAGRDTGLRV
                     DDPVAAVVEAARIFAAERGTAWRLAEVPDLVARITAALGTPTASPGTVGTTPPPPGPAG
                     DRFVVGAPLGRLDARQAAALAGFPVRLTPWRGLVLPGSPDLTGLGLITDPDSPWHGVTA
                     CTGRPGCAKSLADVRTDARNWLGTPHTRPVHWAGCARRCGRPSGDVIEFVATGDGYEET
                     S"
ORIGIN
        1 ttcgtggacc cggtctcctc gcgcagcccg tccacggcgt ccgcgacgcg ccgctcgtcg
       61 cgcccgttga cgaccaccgc cgcgtccgcg agcgcgaggg ccctggccgc cgcgtagccg
      121 atcccggagc tggacccggt gaccagcgcg gtgcggccgg tgaggtcgat cttcacggtg
      181 ctccttcttg taggcggtaa gctgtaacca gcgtaagcaa tacttgcaga cgccgactgt
      241 tgcacacgct tgatagtgca cgcgtggtcg acgacccgca aaccgggaag gggtgaaccg
      301 tgtcactggc cgaggacgcc accgaggcgc gcgcccaggg ctggcggacg ctcgccgcac
      361 tgcacgcgcg catcgaggac aagctcgaac gcgccctgca acgcgcgcac gacctctccg
      421 tcagtgagta caccgttctg gacgtgctcg cccgccagga cgacttccac ctgcggatgt
      481 cgcaggtctc ccaggcggtg gtgctgagcc agtccgccac cacgcggctc gtgacgcggc
      541 tggaggaccg cgggctgctc gggcggtacc tgtgcgccac ggaccggcgg ggcatctaca
      601 ccgagctgac ccctgcaggt gtcgcgctgc tcgacgcggc gcggccgacg cacgacgcgg
      661 cgctgggcga ggcgctggcg gaggccgaac ggctgcccga gctcgcaccc ctggtgaccg
      721 cgctcgccgg actgcccgcg tcaagcactt ccaggtagtg gacggcgttg acgcgccgtg
      781 gcggagttgg tcggatcagc cttgtgagaa acctggaaca gctcgacgcg gcggacgtca
      841 ccttcgtcat ccgggtgacc gcaccacagg cttccagggt cgcgaaccgg gtggcggacg
      901 cgctcaaggc cgcgctgggg caggcggccg tggacgtcga ggtcccggtg cggcgcggcg
      961 ggcccgcgct gcgggtgttc cccgagtccc gccgggtgct gcaccgcggg gaggcggtgg
     1021 agctgacgcg gctggagttc gacctgctgc tgcacctgtg cagccagccc cggcgggtgc
     1081 accgcagggc ggcgttgatg caccaggtgt ggggcgccac gaccgtggtg gacacgcgga
     1141 cggtggacgt gcacgtgcgg cggatccggc ggaagctggg cgacgcggcc ggggtgatcg
     1201 ggacggtgcg cggcgtgggc taccgggtgg accaggagca ccaggtgagg gtggagcggg
     1261 aggactgacc ccttgccgca caccgtgcgc ggggcaccac cgacgaggta gcggggcggg
     1321 aggcggcctc cgggcggtgt ctactcggcg gcgtcgggaa gtggatcgca ctccggaccg
     1381 ttggtccaca gctggtcggc ggttccctcg tcgaggcggc gggcgtagag ctcgaccttg
     1441 cggtggatga cggtcaacgc ctcctggagg tcgtcgacct gctgctgcac gttcgcctcg
     1501 tggcggcgga ggatgtcgaa gcgctcgacc tcgttgccgg ggcccgccag gaccaggccc
     1561 gcgtagcgcc ggatctcggg caggggcatg cccgaggagc gcagcttcgt gcacaccttg
     1621 agccactcca cctcctcggt cgtgaacacg cgcctgcccg cggcgttgcg ccgcacgggg
     1681 gcgacgaaca ggccttcctg ctcgtagaag cgcagggtgt gggtggtgag gccggtcagc
     1741 gcgctgacct ggccgatgct cagggtggtc tccgcggccg tggacatggc tcccactcta
     1801 cgagcttgac ttcgagtcga ctcgaactca tagcgtcgag ggcgacatcg aggaaaggaa
     1861 caccatgccc tccacctggt tcatcaccgg tacctccacc ggcttcgggc gcctgctcgt
     1921 cgaggagctg ctggggcgcg gcgaccgggt cgccgcgacg ctgcgcaagc cggaggcgct
     1981 ggacgacctg caggcggagc acggcgaccg gctgtgggtc ggccggttgg acgtgacgga
     2041 caccgagcag gtccggaagg tcgtggacga cgcgttccag gagctcggca cgatcgacgt
     2101 ggtcgtcaac aacgccggtc acggggtgtt cgcgtcggtc gaggaagcca ccgacgagca
     2161 gatccggcag gtcgtggaca ccaacctgat ggggtcgatc cacgtgatcc gcgcggcgct
     2221 gccgcacctg cgcgcccagg ggcgcgggcg gatcctccag gtctcgacgg cgggcgggca
     2281 ggcgacctac ccgaacttcg ggtactacca cgcgtcgaag tgggggatcg aggggttctg
     2341 cgagacggtg gcacgggaga tcgcgccgtt cggcatcggg ctgaccatcg tggagcccgg
     2401 tgccacgccg accgggttcg gcggctcgct ggcgaccgcg ccgatcatgc cggagtacga
     2461 gaacacgccc gcgggtgacg tgcggcgcgc gctcgcggac ggcagcttca cgttgccgaa
     2521 cgacccgagg aagatcgcga aggccatgat cgagctggtc gacaccggcg cggtgccgct
     2581 ccgcctcccc ctcgggtccg acacctaccg cgacgtgcgg gcggcgctgg tggcccggct
     2641 cgccgagcac gacgagcacc gcgaggtcgc gctgtccgtc gagcgggact agtccctagg
     2701 cggagtgggc cagcgcgctg gagagggagt cgaactcggt gaactcgtcg cgcacgccca
     2761 gcaggtccag caggcgggag acctcgggcg agcggatgag gcggaggtcg atgcggaagg
     2821 cgtgggcgcg gcgggcggtc tccagcaggc agtcgacgcc gaccgagccg aagaacgtga
     2881 ccgaggacag gtccaggacc agtggtcccg agccggaggc cacgctgtcc aggctccagc
     2941 ggagcttgcg gacggtggcg atgtcgatct cccccgagac ggagacgacg gtcgcacccg
     3001 ccaaccgcca gcgctggacg acgagcgaac cttggatgtc cgtgggcacc ggatgctcct
     3061 cagggttgct gatccggtcc ccgacctgga tcggatctcc tcccccaacg tagccgagat
     3121 ccggtgcacc acaagccttt cacctgatcg aggcaacgtc ccgctgggct actcgtggga
     3181 gggttcaccc gtcggcacac cgtccgggtg gccctcggag tcgatggtgt cgcggtgccg
     3241 ctgcatcagc ggcagcagga accacagcgt cgtgaacccc actccggcga cgacgccgaa
     3301 caggatcgcc acccagccgc cgacgatgac ctcaccgagc agcagcaccg ttccggtcat
     3361 cgccgcggcg agggtgccga ggccgacgac ggtgaaccgg tgggcgatgg tgatgatgtc
     3421 ctcgcgcctg ccgcggcgga acagcatgcg gtgccacgcg gcgggcgcgg tcagcagcgc
     3481 caccgagcag gccgcgaaca ggatcgtgac caggtgcgtg acccgcacgt accggtcgat
     3541 gtcctggtag cggtcggtga agacgatcga cagcaggaaa ccgaacagga tctgcacgcc
     3601 cgcctgcgcg acccgcagct cctggagcag ctcgttcagg ttgcgcttca ggcgttcctg
     3661 ctcggattcc tcggcctcgc tcatggctca gttgtacccc gcgccaaaac ggacaaacga
     3721 gtgcgaacgg cctaggcggt catgccctgc ggacgcggtc gaggatgctg gtcaccgact
     3781 cgcgcagcgc ggtggccgcg tcgcccagca acgacggcgg ggacggcttg cggggagcgt
     3841 gagcgtcgtc ggcgtcgagc tccagcagcg cccggacgac cgcgaccacg acgtcggggt
     3901 ggccgagcgg cagggactcg cgcacgacca cgcggacgtc cgcctgctgg ccggtggtgc
     3961 ggtccggccc ctcctcgggg tcgaccagca gcaccgaccg caccaggccc cggtaccggt
     4021 cggccaggta cagcgcgctg gccgccgcgg ggccgccggt cagcaggtgc acgggcacgc
     4081 cgcggccctc gaactcggcc agcaggtcgg acacctcgcg ccacgggccg tcggccgcgg
     4141 gcagcctgca ccagagcacc tggaggtgct ccacgagcgg ctgccacgtg gcggggaggt
     4201 cgccgtgcct gcccaccccg gcggggtcga gcacgacgac ggcgggcgcg tccctgggac
     4261 ccgcccacag cgcggaaggg cctgccgatc gggtctcgtc gacatcgctc atgatcgggt
     4321 gttacccggt tgcggccgct ttaaccatcg gttcgaccgc gtacaccctg taggcgtcac
     4381 ggatggctgc gccacgttgc ggacccgcac cccgccgggt ctcacgccgt gcccgatgcc
     4441 gaagtgcgcg tgcccgtgga cggccagtcc gcgtggttgc cgacgttctc cagcgccggg
     4501 ccccgcgcgt ccttgccgag gtgcacgtcg ccgacggcgg cgataaggcc cgcccgcacg
     4561 gcgagtcctc agtggacttc cgcacttccg gccagtcgag ctgctcccgc agcgcccgcg
     4621 cgaacggcag cagctcgctg gagtcgcagc ggtggccgtc cggcacgagc agctcgcaga
     4681 gcatcacctc ggtcgcgacg gttcctactc cggtgccagt ggtggactct gcggcagccc
     4741 gtcctgctcc cccatgcccg ccagcagctc ccgcaccacc tcgcgcgcgt tgcgggtggg
     4801 cttccagccc agctccgtgc gcgcccggtc ggtcgacagg atcggcgcac ccagcgccag
     4861 gtcgacccag ccgggtgacg tcggctgcgc gtgcagcctc caggtggcgg tcgcgagtcc
     4921 gcggaaggcg gacgccggga cggggacgtg ccgcgccccg accagttccg cgaggtcgcg
     4981 cggaccgatc accggttcgg cggcgatgtt caccgctccc ggcagccggg tctccagcac
     5041 ccgcacgacg gcttccgcca cgtcgtcggc gtgcacgaac tgaagcacca gccccgacgg
     5101 cagcggcagc accgggatgc ggccggacac cgccatccgc agcagtccgg gacggatcag
     5161 cgggccgagg aagaaccgct tgatctccga ggccgcgtcg gcctgcatga tcagccccgg
     5221 tcgcagccgg gacgtcgtga ggtaggggtt gtcgcgccgg acctcgtcga gcagtcgctc
     5281 cacagtggac ttgtgcctgc tgtaggacga cgacgggatg ccgccgaccg gccaccgctc
     5341 gtcgacccgc cgggtcttgt ccgcccgcgt gtacgcgccg accgacgaca tgtgcaccag
     5401 atgcgggacg cgggcgccga cggcggcggc gaagacgcgc ttgctgccca tgacgttggt
     5461 gcggtgcaac gcccgctcgt cctggctggg ctggatgagc caggccaggt ggacgaccgc
     5521 gtcggcgccg agcatcaggt cggccagcgg ctcctcggcg cccggcatgc cgatgtcgac
     5581 ggcggcccag tcggcccgtg agtacggcgg tcccgaggcg gggacccggc gggcgaccgc
     5641 cgtgacctcc acctcggggg gaagtgcgcg cagcagcgcc gttccgacgt tgccgctggc
     5701 ccccgtcacg acgaccctca tgcgcgcacc tcgcccggct cagtccacac tgcgcacgac
     5761 caccgggtcc aggccctcgt ccgggtcgcc gacccagcag acccactcgt cggggtcccg
     5821 cgcgatcggg atcatcggcg cccacatccc gtggccgccg aaccgcgcct cgccggtggt
     5881 cgtcggatcc gttctccgca caatctccac ttgtcccatc tccgtcctct ccgcgcacga
     5941 cgacgccctc ctgccgacgg gaggtcggcg ggagggcgtc accgcgtcat cggggtcatg
     6001 cggacggggt acccacgttc agctgcgcga caccgtcaga tcccgcgcgg cggcgtaggc
     6061 ggccctgacg gccggggtgg aatcggcctc gtagctggtg gtgctcagcg cctcacccca
     6121 gtgcggaggg gcttccgcgc cgctcaccgc ccacgcggcc tggcgggccg cgccgtcggc
     6181 gacgtactcg ccgggagcgg gaaccaggac ggggcagccg aacacggcgg gcgcgatctc
     6241 ccgcaccgcg ggcgactggg cgccgccacc gatgaggagc acccggctga tgggcgtgcc
     6301 cacggcggcc agcgcgtcga tcgcgtcggc caggctgcac agcatgccct ccacagcggc
     6361 ccgcgcgaag tgcgcggggg tcgcggtgtc caggcgcagc ccgtgcagcg cgccggtcga
     6421 gtccggcttg ttcggcgtgc gctcgccttc caggtacggc accaggacga gcccaccggt
     6481 gtccgggatg gacagtgcaa gcctggacag ctccgccagg tccacgccga gcaccctggc
     6541 cgtcgcgtcg agcaccctgg aggcgttcaa cgtgcagacc agcggcagga acgtgccctc
     6601 ggcgtcggcg aacccgctca ccagacccga gacgtccgcc gacgggtgcg gcgatcgagc
     6661 gaacgccgtg ccggacgtgc cgatggagac gatcacgtcg ccgggcccga cctggacgcc
     6721 cagcgcggca ccggcgttgt cgcccgcgcc cgcgccgagg accgctccgc ccgccgtcgt
     6781 gcccgcgtgg tcggcgggtc cgaccacgcg gggcagcacc ggtcgcttgc ccagcgcgag
     6841 gtcgagcagg tcgagccggt actcgccggt ggacggcgac cagtagcccg tgccgctgac
     6901 gtcgctgcgg tcggtgacca gggcctccag ccccggcgcg cccgcgagct tccaggtcag
     6961 ccagtcgtgc ggcaggcaca ccgcggcgac gcgcgcggcg ttgtccggct cgtgctcggc
     7021 gagccaccgc agcttcgtca cggtgagcgc ggcgaccggc acgctgccga ccgcccgcgc
     7081 ccactcctgc ggaccgccca gctccccggt cagcgccgtc gcggcggcgg ccgaccgggt
     7141 gtcgttccac agcagcgccg ggcgcaccac ctcgccgtcg gcgtcgaggc acaccatgcc
     7201 gtgctgctgg gccgccacgg acaccccggc gacgtcgtcg aggccacccg cggcctcgac
     7261 ggcctcgccg agcgcggtcc accacgccgc cgggtcgacc tcggtgcccg tcgggtggga
     7321 cgccctgccc tcgcggacga gggcgcccgt ctccgcgtcg cggacaacta ccttgcagga
     7381 ctgcgtggag gagtcgatcc cggcgacgag cattatcagc gagctcccag gaggtgttcg
     7441 agcgccaact gcgacaagtg cacgaaaccg taaccctgcg cgcccgccgc gtccacgtcg
     7501 aagtcctcga acgcggacct gtccgcgagc aggtcgcgcg ccgtctcacc gcgggagagc
     7561 gtcggcagcc cgagctcggc caccttggcc gcggccagcg cctcctgcac ctcggggtcg
     7621 gcgcggaagg acgccgcgcg ctccttgagc aacaggtagg tgcgcatgtt cgcggcggcg
     7681 ctggaccaca cgccgtccat gtcctcggtc cgcagcggct tgtagtcgaa gtgccgggga
     7741 ccgtcgtagc cgccgttctc cagcaggtcc acgaggaaga acgcggacag cacgtcgccg
     7801 tggccgaaga tcaggtcctg gtcgaagcgc ggaccgtgct ggccgttgag gtcgatgtgg
     7861 aagagcttgc cctgccacag cgcctgcgag atgccgtgca cgaagttcag gcccgccatc
     7921 tgctcgtggc cgacctccgg gttcacgccc accagctcgt ggtgctccag cgtggagatg
     7981 aacgcgagcg cgtgcccgat cgtgggcagc aggatgtcgc cgcgcggctc gttcggcttg
     8041 ggctccagcg cgaaccggat gtcgtagccc tggtcgatcg agtactgcgc gagcgtgtcg
     8101 agcgcctcgc ggtagcggtc gagcgcgaac cgcacgtcct tggccgcgtc ggtctccgac
     8161 ccctcgcggc cgccccagag cacgaaggtc ttcgcaccca gctcggcggc caggtcgagg
     8221 ttgcgcagca ccttgcgcag cgcgtaccgg cgcacgccgc ggtcgttgct ggtgaagccg
     8281 ccgtccttga acaccgggtg ggtgaacagg ttggtggtca ccatcggcac ggtgacgccg
     8341 gtctcctcca gcgcgtcctt gaacagcgag atgcgcttgt cgcgctcgcc ggactcggtg
     8401 ccgaacggca ccaggtcgtc gtcgtggaac gtgacgcccc aggcgcccag ctcggcgagc
     8461 ttgtggaccg cgtgcaccgg gtcgagcgcc gggcgggtcg cctcgccgaa cgggtcctgc
     8521 gcgcgccagc cgaccgtcca caggccgaag ctgaaccggt ccgcacgagt tggctgctcc
     8581 gccacgggtc ctcctccaat aagtttgatg cctaaactta tagcgccttc gtcggcaggt
     8641 caacgttttc gccacgtcgt ccaacggcta ccatcccccg gtgtccccac cgcggccagc
     8701 cgggcagcac accgtccgac ggcacaacag cgccctggtg ctcaacgcca tcgccgacct
     8761 gtccgggcac tcccgcgcgg agatcgccgc gcgcaccggt ctgaccaagg ccaccgtgtc
     8821 gagcctcgtc gaccggatga tcggcgcgaa cctggtggtc gagggcgcgg cggcggtccg
     8881 caccggcccc ggcaggcgcg gcaccgccct gttcctggcc cccgacggcc cgcacgggct
     8941 gggcgtggag atcggcgtcg actacctcgc aacctgcctg atcgacctga ccggcgaggt
     9001 ccgcgcccgc tggatccagt ccgccgacaa ccgcgtcctg tcccccgccc gtgtgctgtc
     9061 gcgcgtgacc aaggcggtgc ggacggcgct ggccgaggcc gaccggatgg gcgtgcgggt
     9121 gggcggcatg ggcgtggccg tgccgggtct ggtcgagtcc gcgaccggca tcctccgggt
     9181 cgcgcccaac ctcggctggc gcgaggtcga cgtgcgcggt gagctgcgca gacgtgccga
     9241 cctggacgac atcccggtgc tcgtgggcaa cgaggcgaac ttcgccgcgc tcgccgagct
     9301 gtggcagggc accggccccc gcgacttcgt ccacgtgtcc ggcgagatcg gcatcggcgc
     9361 gggcatcgtc gtggacggcg gcctgttcga gggcgtgtcc ggcttcggcg gtgagatcgg
     9421 ccacgtgatg gtcgacccgc gcggtcccga gtgcgcgtgc ggcgcgcgcg gctgcctgga
     9481 acggctcgcg ggccaggagg agatctaccg gcaggcgggc gtgctggacg accgcgcgcc
     9541 cgaggagctg atcaccgacc tgctggaccg cctcgcgcac cgcgaccgca ggtccgtcgc
     9601 cgccacccgc tcggcggcca ggtggctggg catcgcgctg tccggtgtgg tcaacctgct
     9661 cgacctgccc accgtcgtgc tgggcggcac ctacgcccgg ctggccccgt ggctgtggga
     9721 accgctgcgc gacgagctgg cccagcgcgt cgtcagctcg acctggtcac cggtcgaggt
     9781 gaccgcgtcc acgctgggct ccgaggccgc ggtccgcggg gcggcgggct cggccgtgcg
     9841 ggcgatcctg gccgaccccg atccctacgt caccgccgcg ctggcctgag gacaggggtg
     9901 gacgtcccca ctagggggcc gtcggaaccc gcgcgccacc ggcggacgcg cgacgtgcgc
     9961 ggtccgcggc gggcgggggt gcgagccggt gcctgcgtcc tcagccggac tcgcggtagc
    10021 tcccggtgta ctccgcccac ttccggtgcc cgccgaccca gcgccgcagc agcgccacgt
    10081 acccgcgcac ctgctcgtcc accggcggcc cgaacgacgg cagctcggcc gccttgcggg
    10141 tgaagtcgcg gacctcctcg tcgtggatct ccacggcgcg gtccacggcc tggtccagca
    10201 cgacggactg ggcgcgcatg gtgaccagca cgaggttgtg cacgccgccg cgggcgatct
    10261 ccgcccggtg ggtgtagagg tcccgcgcgt acccgacgat ccggcacgcg gtggcggcca
    10321 gctcgcgcag ggccgagtgc tcgcggaccg gccggggcag gtcgacgccg tcgaccgggc
    10381 ccgcgaagtg gaacatcggg tgcagcccga cggtgagctc gcagacctcg gcgtgcgcct
    10441 ccggtgtcgg caccgcgccg aggtggtcgt ccagggccga gcgcgagatg gcgtcgaaca
    10501 tccgcccgac ctccgcggcg aagccgtcca cccactccgg accgcccagg gcgaggagtc
    10561 tggcccgcag gtccgccatc gcgccgaccc tcgggtctcc gggcggcacg ggctcgtcgc
    10621 gcagcacggc cagcagcagc gccaggtcct ggtccgacac cccgtcctcg tgcagcagcg
    10681 cggcgaacag ggcccagtcg cccatcagcc gcagctgctc gtagtccgcc cgcgggtacc
    10741 cgtagccgac gagatggccc agctccttgc cggccgcctc gttcatcgcg tgcggcggga
    10801 gcagcccgac cgagacggcc cagccgaccg agtgatcggt caccaggccg tccaccgcgt
    10861 tcgactcggt gtcgaacgcg cacaacacga acggcggcga gatttccgca cgagatccgg
    10921 gcacatcgag tccgctgagt gtgaacgcgc ctacgctcat ggctcaaccc acctccgttg
    10981 actgttctcc tgggccgagc ggcagtgacc ggccaccacc gaaaaataac ggcgtttcac
    11041 aatcttggac aacccctagc ggcccctatg ccacaccgct cggaatccgg tcactggacg
    11101 tcgtagcacc agctcaggac aatcggaggc ggggacgagg aggtgagcgg gtgccgcgtg
    11161 gggaacgtcc gctggacgag ggtgacactc cgctgctgcg gttcgcggcc gatctgcgca
    11221 ccctgaggga ccaggcgggc ggtcgcacct accgccagct gggcaccagg gcgcactact
    11281 cggcgaccac cctctccgac gccgcgggcg gccggaagct gccgagcctg gccgtgacct
    11341 tggcctacgt gcaggcctgc gacggcgacc ccggcgagtg ggaggaccgc tggcgcgagg
    11401 tcgccgccga ggtcgcgccc gccgaagcgc gccgggccga cgagggcacg cccccgtacg
    11461 cggggctcgc cgcgttccag cccgaggacg cgccgtggtt cttcggccgc gagcggatgc
    11521 tcgacgacct cgtcgcccgg atgtcggagc ggcggctggt cggggtgttc ggggcgtccg
    11581 gcgcggggaa gtcctcactg ctgcgggccg ggctcgtgcc ccggatcgcc gagggcgggc
    11641 tcgacgacgg gtcgtgccgg accacgatcg tcgtcacgcc ctccgagctc gacctgagcg
    11701 cggacgtgct cgaccgggtc gtcggcgcgg gcgtggacga gctggtgctg gtggtcgacc
    11761 agttcgagga ggtcttcacg ctctgcgggg acctggccgc gcgcaccgcg ttcgtcgagg
    11821 cgctcctgtc cgcgtcgcgc acccgctgcc gggtggtgat cgggatcagg gccgacttct
    11881 acggccactg cgccctgcac cccggcctgg tcgaggccct gagcgacgcc cagctgctgc
    11941 tcgggccgct gtccgccgag gagctgcgcc aggtgatcat gcgacccgcg gtcaaggcgg
    12001 gctgcacggt ggagacggcg ctggtgacca ggctggtcgc cgacgcgacc gggcagcccg
    12061 gcgtgctgcc gctggtgtcg cacgcgctgc tggagacctg gcggcgaaga cgcgggaccg
    12121 cgctcaccct ggccggctac gaggcggcgg gcggcatcca gcacgcgctc acccagaccg
    12181 ccgaacgcac gttcaccgcg ctggagaccg accagcgcgc cgtggcgagg cagatcttcc
    12241 tgcggctgac cgcgctgggc gacggcaccg aggacaccaa gcgcaggctc acccgcggcg
    12301 agctggacgc cgacgacgtg gacacccagg tcgtgctgga ccggctcgcg cacgcgcggc
    12361 tgctgaccct cgaccaggac gccgtcgaga tcgcgcacga ggtcctgatc cgctcgtggc
    12421 cccggttgcg cgggtggctg cacgagaacc gcgaaggcct gcggacggcc cgccagctca
    12481 ccgaggccgc cgccacctgg aacctgctct cccgcgagcc cgacgccctc taccgcggca
    12541 cccggctgga caccgccgtc gagtgggccg cgggcggcga ggccaggctc agcacccgtg
    12601 agcaggagtt cctcgacgcc agcctggccg accgcgaccg ggagcaggcg ctcgcactgc
    12661 gccggacgcg caggctccgg cagctcgtgg cgctgctgct ggtgctgctc ctgctcgcgg
    12721 gcggcgcgat cgtgcagacg atccgggccc aggacgccgc cgacgagcag cgcaacatcg
    12781 cggtggcgca gcagatcgcg ggcgcggccg tgcggatgcg cgagtccaac cggccgctcg
    12841 cccagcagct cagcgtcgcc gcctaccggc tggagagcac cagggacgtg gtggacgggc
    12901 tgctgaccac gtcggcggcc aactggaaca agcacctgat ccgccgggtg gtcccgacca
    12961 cggaggtccc gatggggccc gacggcagcg cggtccgcgg caagggccag gtgccgcagc
    13021 aggacagctc cggcgacctc ggctcggtgc agtcgctcgg gttcaccgcg gcgggacggg
    13081 tcctggcgac cactcccgac gagctgtggg acctgaccga cgcgggcaaa cccgtttcgc
    13141 tgcaccactt cccgaaccgg atggtcgcga ccgcgctgtc ggccgacggc acccggatgg
    13201 cgaccgtcga cgacagcccc gacaacaccg tgcggctgtg ggagctcaag cggcccgagg
    13261 cgcccgcgtt cgtgtcgacc gtgccgcaca gcggacaggg cggccgcgag gtgcggttcg
    13321 accagagcgg tcaggtgctc gtcaccatcg acgacgacag cacgaccacc ctgtggcggc
    13381 tggaccggcc ggacggaccg cacgagttcg gcaggctgac cagcatcccg cacatctcca
    13441 cgatggcgct gtcgcaggac cggcggctga tggccaccgg cggcgcggac ggcgtgatcc
    13501 gactgtggga catggccgac ccgtggcacc cggcgaagct cgtcgagctg ggggtgcagg
    13561 ccgcggaggt gcgcgcgctg gcgttctccc gcgacggcag gcacctcgcc agcgccgcgg
    13621 gtgaccagac cgtacggctg tgggacatct ccgacccgcg cgctcccggc gagcccgcga
    13681 cgatcaccgg accgaccacg tccgtgcaca cggcggtgtt cgtgcagagc gacgacggcg
    13741 gtgacgacgt ggtcgtgatg acgtcgagcg gcgacggctc gtcacgtcgg tgggacttcg
    13801 acgtggcgcg ggccgtgagc cgcctctgca cgggcagcac ggcgctgacc cgcgcggact
    13861 gggaccgctt cttccccggt ttccggttca ctccgccgtg cggatgacct gtgctgcggg
    13921 aacacccgga agagccgata ctcattcggg tgagcactcc tcgtgacgac cgcgcgaccg
    13981 acctccaccc caccgacctc ggggtgccgg ccgatccgtc gacgccggcc gacgagtcgg
    14041 tgacccatcc gccggtgctc cccgacacca ccgacccggc tcccgtcccg acgcagccgc
    14101 ccgcgtcgca cgtgaagctg aagccgacca ggatcagcgg cacctgggtc gcggtcatca
    14161 tcgcgatctt cgtgctgatc ttcctgctcg tcttcatcct gcagaacctc gcgggcgtca
    14221 ccatccactt cctcggcggt gccttcacgc tgccgctggg cgtggcgctg ctgttcgccg
    14281 ccatcggcgg ggcgctgctg gtcgcgctgg tcggcgcggc ccggatcatg cagttgcggc
    14341 gccagacgaa gagggccctg cgctgaggtc ccgcgtcgcc ggttagcgcc cgagcgcgcg
    14401 gcacaccacc ttggcgaagg tgttgggcgg caacggttcc aacgccgtcc acgcactgtc
    14461 cacatgcgac agcgtttcgt cgcggaacgc ctgaaccgcg tcgcacgcca ccagctccgc
    14521 ggccacctcg cgcacggtca ggtcgtcggc gccgccgcgc ccggcctccc acacccgtgc
    14581 cgtccgctcc ggcgccaacg gcatcgtcac ctcgcccgac cgcaggtcct cccccgcgag
    14641 ctcggccacc gcgcggcacc ggagggcgcc ggcgccgtcg gtcgagccgg tccgccgcat
    14701 gagtcacccc cattaccctg cgtggtggat gatcacgcag tgcacaaccg ctaagcgctg
    14761 gccctgacga ccagggacgt cggcagcagc agcgacggcg gcaggccttc ctcgcccgcc
    14821 agctcggcca gcagccgcca ggtcatcgtc cgccccagct gctccacgtc ctgcttcacc
    14881 gtcgtcagcg gcggcaccgc cgtcgaggcc agggcgaggt cgtcgaaccc gaccaccgcg
    14941 acgtcctccg gcacccgccg cccgttggcg tgcaacgact gcaacgcccc cagcgccatg
    15001 atgtccgccg ccacgaacac cccgtcgatc gacgggtccc tggccagcag ctcggtcatg
    15061 gccgccgcgc cgctctccgg cgtgaagtcc ccgtaggcca ccaggtcgga ctccatgccg
    15121 aactcgctga gcgcccggcg ccagccgctc aggcggtcca tccccacggc catgtccttc
    15181 gacccggcga tggtcgcgat ccgcttccgc cccttggtca ccaggtgccg ggcggcctcc
    15241 agggcgccgt tgaagttgtc cgcgtccaca tagggcacgc cggaggcgcc cagcggacga
    15301 ccgcccacca ctatcggcag cccggcgtcg gccagcgtct gcggcagcgg gtcctggccg
    15361 tgcaggctga tcaccagcgc accgtccacg tggccgccgc agaggtagcc gaccaggtcc
    15421 tgctcgtcgt cctgctggct catcatcagc acgagctgca cccggtgccc ggcgagctcg
    15481 gcgtgcaccc cgcgcagcac cccggcgaag aacgggtcgg acagcacgcg gctgccctgc
    15541 tccgacacga ccagcgcgat gcagttggtc cggctgcccg ccaacgtccg ggcggcctgg
    15601 ttggggctgt agcccaggct cacgatggcc gcgagcacgg cttcgcgggc ccgcgagctg
    15661 acgtactgct cgccgttgat gaccctggac acggtcgact tggagacccc cgcctggcgg
    15721 gcgacctctt cgatccgcgc cccgaggcgg cggccgcggg cggcctcagt catgcggacc
    15781 cgtaccgctc acccgcgcac ccaggacgtc catggatcac ataataggtc cagacgaccc
    15841 caggaccagc aggacacccg ttaccaccac cacaccaccc gaccgggcca tgccacccac
    15901 cgcactcccg cggcggcggg tggcggcccg cgcagggggt gcgctaccgg tcctcgagat
    15961 ccccctcgga ctccaggaac acggcctgca gggccgccag cgtctcggct tccgggtgct
    16021 cccacatgcc ccggttcgcc gcttccagca gccgttcgga gatcccgtgc agcgcccacg
    16081 ggttggactc ggtcatgaac ttccggttct ccgggtccag cacgtaggtc tcggcgagct
    16141 tctcgtacat ccagtccgcc accacgccgg tcgtcgcgtc gtagccgaac aggtagtcca
    16201 cagtggccgc cagctcgaac gcgcccttgt acccgtgctt gcgcatggcc gacagccagc
    16261 gcgggttcac cacgcgggcg cggaagacgc gcgtggtctc ctcgttcaac gtccgggtgc
    16321 gcacggcgtc gggccgggtg ctgtcgccga cgtaggcggc gggcgccttg ccggtcagcg
    16381 cgcggacggt cgcgaccatg ccgccgtggt actggaagta gtcgtcggag tccgcgatgt
    16441 cgtgctcgcg ggtgtcgatg ttcttggccg ccacggcgat gcgccggtag gccgactcca
    16501 tgtccggccg cgcctgcacg ccgtcgagct cacggccgta ggcgtacccg ccccagaccg
    16561 cgtacacctc ggccaggtcg gcgtcgtcgc gccagttccg gctgtcgatc agcggcagca
    16621 ggcccgcgcc gtaggcaccc ggcttggacc cgaagatccg catggtcgcg cggcgggcgt
    16681 cgccgtgggt ggccaggtcg gcctgcgcgt gcgcccggac gtagttcgac tcggcgggct
    16741 cgtccagcgc cgccaccagc tgcacggcgt cgtccagcat ggcgaccacg tgcgggaagg
    16801 cgtcgcggaa gaacccgctg atccggacgg tcacgtcgat ccgcggccgg tcgagctcgt
    16861 cgagcgggac ggcctccaga ccggtgaccc ggcgggactg ctcgtcccac acgggacgga
    16921 cgcccatcag cgcgaacacc tcggcgatgt cgtcgccgga ggtgcgcatg gcgctcgtgc
    16981 cccacaccga cagccccacc gacggcggcc attcgcccgt ttcgtcccgg tagcgcgcca
    17041 gcagcgagtc cgccatcgcc tgcccggtct cccacgccag ccgcgacggg atcgccttcg
    17101 ggtcgacgga gtagaagttg cggccggtcg gcaggacgtt gaccagtccg cgcaacggcg
    17161 acccggacgg gcccgcgggc acgtagccgc cgtcgagcgc gtgcaggacg ttggtcatct
    17221 cgtcggtcgt ccgggcgagc ctcgggacga tctcgtcggc cgcgaactcc aggatgcgcg
    17281 ccacctggtc ggagtcggtg agcccgcgcg ccgcctcgcg cgcccagccc gcgtcctcca
    17341 tgccctgcac gagcgcgcgg gcggtggtct cgacgtcgtc ggtggcgacg cgggtctccg
    17401 agccgtcctc gttgagcccc agcgcttcgc gcagccccgg cagcgcggcc acctggcccg
    17461 cccacatctg cttcgcctgg agcatcgcca gcacgagccc gacgcgggcg tcgccggtgg
    17521 gcgcctcgcc caggacgtgc aggccgtcgc ggatctgcac gtccttgatc tcgcacagcc
    17581 acccgtcgac gtgcaggatg aactcgtcga actcggcgtc gtgcgggcgg tcgtccaacc
    17641 cgaggtcgtg gtcaagcttg gcggcctgga tgagggtcca gatctgcgct cggatggcgg
    17701 gcagcttcgc cgggtccatc gcggcgatgt tcccgtgctc gtcgagcagc tgctccaacc
    17761 gcgcgatgtc gccgtagctg tccgcgcggg ccatcggcgg gaccatgtgg tcgaccagcg
    17821 tggcgtgcgc gcgccgcttg gcctgggtgc cctcgccggg gtcgttgacc aggaacgggt
    17881 agatcagcgg caggtcgccc agcgccgcgt cggtgccgca gcccgcggac atgccgacgg
    17941 tcttgccggg cagccactcc aggttgccgt gcttgcccac gtgcaccacg gcgtgcgcgc
    18001 cgaagtcgtc ggccagccag cggtaggcgg ccaggtagtg gtggctgggc ggcaggtccg
    18061 ggtcgtggta gatcgcgatc gggttctcgc cgaagccgcg cggcggctgg accatcacca
    18121 cgacgttgcc cgcccgcagc gccgcgagca cgatctcgcc gtcggcgtcc ttggaccggt
    18181 cgacgaacag ctcgccgggc gcctgccccc agtgctgctc catctccgcg cgcgtgtcgt
    18241 cgggcagggt ggcgaagaac tcgcggtagc gggccgcggt catccggacc gggttgccgg
    18301 tgaactgctc ctcggtcagc cagtccgggt cctgcccgcc cgccgcgatc agcgcgtgga
    18361 tgagcgcgtc gccgtcgagc tgctccacgc cgggcagctc gccgggcgcg ccgatgtcgt
    18421 acccctgctc ccgcaacgcg gtcagcagcc ggacgacgct cgcgggggtg tccaggccga
    18481 ccgcgttgcc gatgcgcgag tgcttcgtcg ggtacgccga cagcatcacc gcgatcctgc
    18541 gttcggcggg cggggtgtgc cgcagccggg cgtgggccag cgcgatgccc gcgacccgcg
    18601 ccgcgcgttc cgggtcggcg acgtagacgg tcaggccgtc ctcgtcgatc tccttgaagg
    18661 agaaggggac cgtgatgatc cggccgtcga actccgggat cgcgacctgg gtcgcggtgt
    18721 ccagcggcga caggccgtcg tcgctgtcgt cccacgccgc gcggctgctg gtgaggcaga
    18781 gcccttgcag gatcggcacg tccagcgcgg ccagcgcgcc gacgtcccac gcctcgtcct
    18841 caccaccggc gcccacggtc gcgggcttgc tcccgcccgc ggccagcacc gtgacgacca
    18901 gcgcgtccgc cgtgcccagc acggccagca gctcggcctc ggcggtgcgc agcgacgagc
    18961 agtacaccgg cagcgcgcgg ccgcccttgg cctcgacctg gtcgcacagc gcgtgcacga
    19021 acgcgacgtt cccggcgacg tggtgggcgc ggtagtagag gacggcgacg gtcggcccgt
    19081 cggtggtctt gccctcggtg acgggcacag ggcgttccag caggccccag ttcggcgccg
    19141 ggaccggcgg cgcgaagccg ttgccggtca gcaggatcgt gtcggacagg aagttgtgca
    19201 gctccgcgag gttcgccgcg ccgccgtgcg cgaggtaggc gtgggcttcc gcgcacacgc
    19261 cgccgggcac cgtggacagc tccatcagcg gggcgtcggg gttctgctca ccgccgagca
    19321 cgaccaccgg gcgcgggccc gccaggacgg cgtcgaggcc ctcctcccac atccggcggc
    19381 cgccgaggat gcgcacgacg acgacgtcgg cgccctcgac cagctcgggg aggtcggcca
    19441 cctccagccg cgacgggttg gcgagccggt agtccgcgcc actggcccgc gctgacagca
    19501 ggtccgtgtc ggaggtcgag agcagcagga tcacgcgaaa gctccactcc ggggtcctcg
    19561 ccccaagtcg tcggcacacg gcggagcgga gttcctggct cccggatcgc tccggtgaca
    19621 gtggcgggac cgcgtcggac ttccaccgac ttcctcgctg cttcgccgtt cggcctgaca
    19681 gtacagccgt cacgtagcat ccggcgcgtg ccaacggagc gaacccacgc cgacgcctgt
    19741 ccaggcgcta tcgacgtgca ccccgccgcc gacggcgggt tggcgcgcat ccgggttccg
    19801 ggcggaactc tgacgaaagt ccagttcagg gccatcgtga cggcctcggc cgagctgggt
    19861 gacggtcagc tggagctcac ctcgcgggcc aacttccaga tccgcggact ggcggacggg
    19921 gcccagttcg agctcggcga ccgcatggcc gaggcgggtc tgctgccgtc gctgacccac
    19981 gaacgtgtgc gcaacatcat cgccgcgccc ctctccgacg acacccaggc cgtcgtcgac
    20041 gcgctcgaca gggcgatctg cgccactccc gagctcgccg acctgcccgg ccgcttcctc
    20101 gtcacggtcg gcgccgaggt cgccggactg ggcgccgaca tcggcctggt cgacgacgcg
    20161 ctcctgctcg ccgggcgcga caccggactc agggtggacg acccggtggc cgccgtggtc
    20221 gaggccgccc ggatcttcgc cgccgaacgc gggacggcgt ggcgactggc cgaggtgccc
    20281 gacctcgtgg cccggatcac cgccgccctg ggcaccccca cggcctcccc cggcaccgtc
    20341 ggcacgactc ccccgccgcc cggcccggcc ggtgaccggt tcgtcgtcgg cgctccgctc
    20401 ggccgcctcg acgcccgcca ggccgccgcc ctcgccggct tccccgtccg gctcacgccg
    20461 tggcgcggcc tggtcctgcc cggctcgccc gacctcaccg ggctcgggct gatcaccgac
    20521 cccgactccc cctggcacgg cgtcacggcc tgcaccggac ggcctggctg cgcgaagtcg
    20581 ctggccgacg tgcggaccga cgcccggaac tggctcggca cgccccacac ccgaccggtg
    20641 cactgggcgg gctgcgcccg acgctgcgga cgaccgtccg gagacgtgat cgagttcgtc
    20701 gcgaccggcg acggctacga ggagacgagt tgacgagcta cctccaggac ggcgccgaga
    20761 tctaccgccg gtcgttcgcc acgatccgcg ccgaggcgga cctcggcggg ttaccggccg
    20821 acgtcgcgcg cgtggcggtc cggatgatcc acgcctgcgg gatggtcgac ctggtgcggg
    20881 acatcgcctt ctccgccgac gcggtcgcga acgcgcgcgc cgcgctgctg gcgggcgcgc
    20941 cgatcctctg cgacgccacc
//
