LOCUS       NZ_PVTF01000002        23069 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Umezawaea tangerina strain DSM 44720 Ga0180964_102, whole genome
            shotgun sequence.
ACCESSION   NZ_PVTF01000002
VERSION     NZ_PVTF01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Umezawaea tangerina
  ORGANISM  Umezawaea tangerina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Umezawaea.
REFERENCE   1  (bases 1 to 938859)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 938859)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Expected Final Version            :: No
            Genome Coverage                   :: 86.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003002815.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:47:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,483
            CDSs (total)                      :: 9,418
            Genes (coding)                    :: 9,322
            CDSs (with protein)               :: 9,322
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 20 of 97
            Pseudo Genes (incomplete)         :: 83 of 97
            Pseudo Genes (internal stop)      :: 2 of 97
            Pseudo Genes (multiple problems)  :: 8 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 791628
            Orig. end                         :: 814697
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVTF01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23069
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="3"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23069
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23069
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13069](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13069)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(79..1221)
                     /locus_tag="CLV43_RS09585"
                     /old_locus_tag="CLV43_102709"
     CDS             complement(79..1221)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227983.1"
                     /locus_tag="CLV43_RS09585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102709"
                     /product="histidine kinase"
                     /protein_id="WP_106186678.1"
                     /transl_table=11
                     /translation="MTGLLRSLWDEPRPALVPPVGWRDRVLVGVLAALVVVEGLWRPDL
                     RWPVVATGVALVLVPLLLVRRSRPLLALVVAFVVTGLSPLLTGGRAAESYSLAFVLLLV
                     FSVARWGSGREVVLGLAVVVAKVSLSVVFGQVDAGDAGAGFVVTFSAVTFGAALRYRAG
                     ARVRELDRVKLLERGRLARDLHDTVAHHVSAIAIRAQAGLATAPANPDAAVDALRLIEA
                     EASRALVEMRTLVHVLRQDQEAELAPTPRVSDLERLATGGSRSGPSVDVGIDGDVDDLP
                     PTVGTAIYRLAQESVTNARRHARHATRIVVRVAADDTSVRLRVSDDGDATTTRPTGEPG
                     YGLIGMIERAGLLGGTCEAGPDPDRGWTVTAVLPRAGAAG"
     gene            complement(1295..1774)
                     /locus_tag="CLV43_RS09590"
                     /old_locus_tag="CLV43_102710"
     CDS             complement(1295..1774)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076088.1"
                     /locus_tag="CLV43_RS09590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102710"
                     /product="flavin reductase family protein"
                     /protein_id="WP_106186679.1"
                     /transl_table=11
                     /translation="MTSAELDRITGTAFRSFMRDWATGVAVVTSTQGAAPVGCTVNAFT
                     SVSLDPPLLLVSLARGSRTLAAITASKVFGVNVLDDRQGELAKRFAVGTGDRFAGTPHR
                     RELGVPVIEDVLAAVVCEVEWCVVGGDHVLVLGRPRWCSRERAGEPLVFFRGGWR"
     gene            complement(1771..3825)
                     /locus_tag="CLV43_RS09595"
                     /old_locus_tag="CLV43_102711"
     CDS             complement(1771..3825)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1272: TPR
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024824.4"
                     /locus_tag="CLV43_RS09595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102711"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_106186680.1"
                     /transl_table=11
                     /translation="MSEHLWRVDPRSAHDDGADFRVDSHRRLRGPYTGMGTLLRELVPD
                     VQSRWPDLVRSHSIEILSAAPELTEAIGAAPETLTSVAIPSERTRIYPANRTRRLAHGV
                     VELLESYAALADRHLVLSFTNVDEADHTDQEFLAIAVRRARSGRVRFVVGTRTDAVVEE
                     LAEALRAHADREDVVNPPADGPVRPAEELVRAFVAGDCTSNDPHELAAYAEADPVVVAA
                     LHDARAAELADGDWSLRLGALLHHLEHGGDPTGVGGDAMLDAANHCFDMGFYHSLLEYV
                     PRGRAITDPEEQQERYWLLTTKMTTGLASLNRSLESLPLYDELRGRYTLPMVHMFCSYA
                     MAMLYTRHHPPEHKDHHQAKILLNNAVAIASVLPDPEQRIFQTVFQKNGLALVETHLDN
                     LPGALKLVTDGLARLDRELDPGKHKLHRSVLVNNRSKVLGALGRYEEALADLDTVIGLD
                     PNYPDYYFDRADVRRKLGDPEGALLDYATATTLTAPFYELHYNRADVLVEVGDLEGAIA
                     ELAYVVDLEPDQVDARLNLVSLLLDTGDLDTAAVHLAEGLRLHPADARLVHANGLLALE
                     TDDRDLARKEFDRALELDPHLVAALADRAGLAHDDGAHDAAIRDLTTAVEVDPDNPDLL
                     YNRGFVHQAAGHLAAAVDDYTRALVLPGADRDELLRQRSLCRDELVDAR"
     misc_feature    complement(3815..3830)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.08"
                     /tool="antismash"
     gene            complement(3844..4998)
                     /locus_tag="CLV43_RS09600"
                     /old_locus_tag="CLV43_102712"
     CDS             complement(3844..4998)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV43_RS09600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV43_102712"
                     /product="hypothetical protein"
                     /protein_id="WP_106186681.1"
                     /transl_table=11
                     /translation="MSASHLEFHPLTFVQDRDGVTVGRFDVESYAVLPEDGAALLRRLF
                     DGMPVAEAAAWYEAEFGEPIDMADFVEALRELEFLREDGEVVEVAPVRYRALGRAAFSP
                     PAWLGYAALVTAAVLVMVARPELRPHGSSVFFTPSLVAVQVVLTFTQVPAVLFHEWFHV
                     LAGRRLGVPSKLNVSRRLYFIVFETELNGLLSVPKSKRYLPFLAGVVADVLLFSALTLV
                     AAVDDSAWGGRLALAIAYLVLLRLVWQSYLFLRTDLYYVLTTMAGCTNLHEAASAYLRN
                     RFHRLPFVRKSTVDDSAFAPRDRQLAPWFALTSVAGVVFLLVTVLLAIVPVVLEFGARL
                     WTALSGGTAGGAGFWDSAVAVLLIVVQLVLLTLVTDRRTDRTST"
     CDS             complement(5074..5292)
                     /gene="allorf_796702_796920"
                     /locus_tag="allorf_796702_796920"
                     /protein_id="allorf_796702_796920"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPPHLLRVHPKNTGARPPWHGVRWPAASSPSPAARPIPPADQEVK
                     NMKKIAIRKTGSIKLTSSAAGYCSPCC"
     CDS_motif       complement(5095..5292)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MPPHLLRVHPKNTGARPPWHGVRWPAASSPSPAARPIPPADQEVKNMKKIAIRKTGSIK
                     LTSSAAG"
                     /locus_tag="allorf_796702_796920_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(5074..5094)
                     /prepeptide="core"
                     /locus_tag="allorf_796702_796920_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.30"
                     /molecular_weight="610.8"
                     /monoisotopic_mass="610.2"
                     /core_sequence="YCSPCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPPHLLRVHPKNTGARPPWHGVRWPAASSPSPAARPIPPAD
                     QEVKNMKKIAIRKTGSIKLTSSAAG"
                     /leader_location="[5094:5292](-)"
     misc_feature    5139..5153
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.33"
                     /tool="antismash"
     gene            5337..5885
                     /locus_tag="CLV43_RS09605"
                     /old_locus_tag="CLV43_102713"
     CDS             5337..5885
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014494.4"
                     /locus_tag="CLV43_RS09605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102713"
                     /product="flavoprotein"
                     /protein_id="WP_211304290.1"
                     /sec_met_domain="Flavoprotein (E-value: 1.5e-18, bitscore:
                     62.6, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDDALSIIVSGSSAALGMPGYLTWLRQEVDLSLRVLLTRGAERF
                     LRREVLDWYAEEVYTSDDPTLNPTEFAKRSLGVVVLPSTANMLAAAALGLAGTPAQTVL
                     LACDGPALFFPSMNQTMWKKTSTQRHVTTLREDGHTVAEPQERAVFELWRRENAMGIGM
                     PAPDEATELIVGWLEGGSS"
     CDS             5882..6121
                     /gene="allorf_797510_797749"
                     /locus_tag="allorf_797510_797749"
                     /protein_id="allorf_797510_797749"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MMVSLGRGALCGRVGVAAGDFECGRLDLGPLFWASSGEKGQVVEP
                     ARRLIVSPKTPSQVGRTGGRACSVSLGLGGLLGW"
     CDS_motif       5882..5938
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MMVSLGRGALCGRVGVAAG"
                     /locus_tag="allorf_797510_797749_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       5939..6121
                     /prepeptide="core"
                     /locus_tag="allorf_797510_797749_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.90"
                     /molecular_weight="6080.0"
                     /monoisotopic_mass="6076.3"
                     /core_sequence="DFECGRLDLGPLFWASSGEKGQVVEPARRLIVSPKTPSQVGRT
                     GGRACSVSLGLGGLLGW"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMVSLGRGALCGRVGVAAG"
                     /leader_location="[5881:5938](+)"
                     /alternative_weights="6098.0"
                     /alternative_weights="6116.0"
                     /alternative_weights="6134.0"
                     /alternative_weights="6152.0"
                     /alternative_weights="6170.1"
                     /alternative_weights="6188.1"
     CDS             complement(6027..6233)
                     /gene="allorf_797655_797861"
                     /locus_tag="allorf_797655_797861"
                     /protein_id="allorf_797655_797861"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGCADGLSRRTEGEAGGERPTGAPTTIGRAERTKCTPITNRANRP
                     TPTKPSKLVRPCGRLDLGFLGLQ"
     CDS_motif       complement(6183..6233)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGCADGLSRRTEGEAGG"
                     /locus_tag="allorf_797655_797861_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6027..6182)
                     /prepeptide="core"
                     /locus_tag="allorf_797655_797861_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.40"
                     /molecular_weight="5336.2"
                     /monoisotopic_mass="5333.0"
                     /core_sequence="ERPTGAPTTIGRAERTKCTPITNRANRPTPTKPSKLVRPCGRL
                     DLGFLGLQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGCADGLSRRTEGEAGG"
                     /leader_location="[6182:6233](-)"
                     /alternative_weights="5354.2"
                     /alternative_weights="5372.2"
                     /alternative_weights="5390.3"
                     /alternative_weights="5408.3"
                     /alternative_weights="5426.3"
                     /alternative_weights="5444.3"
                     /alternative_weights="5462.3"
     gene            complement(6316..9237)
                     /locus_tag="CLV43_RS09610"
                     /old_locus_tag="CLV43_102714"
     CDS             complement(6316..9237)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="CLV43_RS09610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102714"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_106186682.1"
                     /transl_table=11
                     /translation="MTAVVVPSPRTVGRTAESRVLTTAVEDGSRQRGGTVFVLGEAGIG
                     KSRLVTEAAEHALSRGMRVLRGRASASGAPAPFRPISEALFSLTRESGLPTDPELVPYR
                     PSLARFLPEWRDATAFGDDESLLVVAEGLLRLLAVLGRDVGCLIVLEDLHDADAETLAI
                     VDYLADNLVGQPVVLLTTARSQAGPAWELVRGGGRRSGVTVVEPGRLDPEGVRELVASC
                     LGVPSDDVPGAAVDRLFRDSDGVPFVVEELLDSMVAVGGLVRDPDGWSVRGEGHTPVPV
                     TVVLSVSHRVDRLAPEVAALLHVAAVLGRRFPLSVVRAVCGLEQADLLRHLRSAVEAQL
                     VTPDRPAPEWYSFRHALTADALLARLGASERAELARRAADAVEVDHPGLPGEWCTSAAI
                     LRLESGDVATAAGLFAEAGRRMLADGAAATAVDLLRRAHDLLAHDDEERVAVLELLLNA
                     LAEAGQVEQALALAPDLDDPGLSVERQASLHTVLARVAVRAGLWAQGAEEIASTRALLG
                     PDVAPRLTAEVDVIAATLTLETPGADRRTVAERLVRRALRDAEQADLPEVACEALELLG
                     TLTRQQDLTESDGYFTRMAELAHRHRLRSVQLRALARSGVNENLRSGRAARLRRAHLQA
                     FQVGAITEGYLLEVNLVMVAVLRGEFVRAAELADHCVPVVTRMRLRYSIRYVLMAKAAM
                     FAHRGRRSGMTRALAEFDRWDGRDSHQMPLVHGLCEAFCALLEENRPQAVRALDDAIAS
                     EAENPTNYVLAGRYGLRVLLGVLGGEMGWREYEEAAAVPAGALAWNRQFLHLAKAVLLG
                     RAGQSAAAAAAMVEHLQISEPFAMARHLGLRLAAEAAISDTWGSPANWLREAETYFHQD
                     DVPAITSACRVLLRRAGVSATQHRNGTANLPAPIRSMGVTVREHEVLRLLAERLGNTEI
                     GKRLFISPRTVEKHVASLLAKTSQPDRAALNRFAIDHVIGGMD"
     gene            complement(9266..9526)
                     /locus_tag="CLV43_RS09615"
                     /old_locus_tag="CLV43_102715"
     CDS             complement(9266..9526)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03898.1"
                     /locus_tag="CLV43_RS09615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102715"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_106186683.1"
                     /transl_table=11
                     /translation="MTAPTIDVAETVRLWKDPDARWKLAPDSCPPHPAGEMALTPAGPT
                     GAGALCASGVTAADTWTLSTFTPPSVSGPCLGYGSFADDRY"
     gene            complement(9677..9934)
                     /locus_tag="CLV43_RS09620"
                     /old_locus_tag="CLV43_102716"
     CDS             complement(9677..9934)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV43_RS09620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV43_102716"
                     /product="hypothetical protein"
                     /protein_id="WP_106186684.1"
                     /transl_table=11
                     /translation="MTAPAIDVAETVRLWKDPDARWELDRASAPPHPAGEIMLTPAAPE
                     GAGPLRMHGVVAADLLTLTTFGTPSVSAPCLGYGLTDDLD"
     gene            complement(10001..13069)
                     /locus_tag="CLV43_RS09625"
                     /old_locus_tag="CLV43_102717"
     CDS             complement(10001..13069)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="CLV43_RS09625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102717"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_170155767.1"
                     /sec_met_domain="DUF4135 (E-value: 1.9e-100, bitscore:
                     332.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5.6e-16, bitscore:
                     53.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVGRTGADVGGWESGWWFGGRTLTERLASGAGTGTSASEDAERR
                     ARTRLDRWRAEHGAGSGDRFTRRLASVGVDEDDLLRLLGERSATGPKPAWATGVERVVD
                     RAVGPAAVDGRSWRSAFAVVVKPFVQDARGRVAAEVADLGPDVFVDADDVVDRFADALR
                     RTLVWTSTRVLVLELNVARVTGLLDGDTPEERFAAFARRAGTRAGRTALLTEYPVLARL
                     LWQHCDVTAAAFTELLHRFVDDRADIVRELLGGRDPGPLARVDVGAGDTHHDGRAVAVL
                     GFADGTRVVHKPRPSAVHRHFNQVLTWLGSVLPGLDPRTLAVLDRGDWAWTEFAAHHQV
                     SDTAQVERFHHRQGALLALLHVLDVTDQHFENLVACGEQPVLVDVETLFHPTWATRDLA
                     DDPAARALEASVLRTALLPQPMTGANGVLDISGVGGDKGATLPDDVVGFDGAGTDRMRL
                     VRGPEVLGGAENRLRLDGVDVDPGEYLEHLVAGFRAAYEAVLTHRADLLAPGGPLDAFA
                     TDVVRVIVRDTSEYVRLLDESTHPDVLRDALDRDRVFGHLWSSDADPARERLVGHEVAD
                     LWAGDVPLFTTTPTSRDILTAHGVRVPDALGETGLDRVRRKVEALGEADLRTQEWVIRA
                     SFATRGDRGAHSPRPRPGRRPAAERPDPDRLLAAARAVAGGLLADAHDDGERVNWVGLE
                     HDRSWRVLPLGASPATGFPGVALFLGQLAAITGDDRCADVARRSLRSVPSLLDRFGSAE
                     AAMPTGFAGLGGLAYALSHLAVLLDDPDLRGWTATAVEAAAAHVGRAGTTDLMGGTAGC
                     LAAMLAVHRTTGLDSAWRTATACAGLLERADEPSTTGFAHGSAGTTWALWRYAVAASGP
                     CRREPVLADSAEADGGTWCRGASGVGLARADVLALERDPLMAGAFDRAVDGVLRRPAAV
                     DHSLCHGELGTLELLTAAAARGHEAAAAEAPRRIGDLLAALDRDGPVSGTPDAVRTPGL
                     LDGLAGIGHGLLRLGFPDRVPAVLLLGAARPPR"
     misc_feature    13260..13271
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.15"
                     /tool="antismash"
     gene            13384..14907
                     /locus_tag="CLV43_RS09630"
                     /old_locus_tag="CLV43_102718"
     CDS             13384..14907
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015105193.1"
                     /locus_tag="CLV43_RS09630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102718"
                     /product="alkaline phosphatase D family protein"
                     /protein_id="WP_106186686.1"
                     /transl_table=11
                     /translation="MGTVTRRALITGVVALTALGAGSARVVDPFTLGVASGDPTPDGVV
                     LWTRLAPYPLAENGLGGMPSRVVEVSWELARDERFRHVVRRGRQWARPESGFSVHVEVG
                     GLEPGREYFYRFATGGHLSRTGRTRTTPAPGTMTTPLTMAFASCAQYEHGYFTAYRRLA
                     EDEPDLVLHLGDYQYEYRKGVHVAPNGNVREVDGPETVTLADYRHRYAQYKSDADLQAA
                     HAAAPWAVVWDDHDVADNWAGSHYSKPEIPQPDFPARRAAAAQAYYENMPIRSKPRGFD
                     LRLYRRVGWGGLTTFHMLDTRQYRDDQPCGDGIKPCPERLEPTRTMLGAEQERWLLDGF
                     RTSSARWDVLGQQVFFSQYDHTPGPVQETNLDAWDGYAADRDRVVAGFSSVRNAVVLTG
                     DVHAAWGAEVKERWDDPASRTAGTEIAGTSITSGGDGSEVYPETPEWFAENPHIKYFNN
                     RRGYVRTRFSPDEVRVDFRGLDHVSRPGAPVSTKASFVIEDRVPGLNPV"
     gene            complement(14921..15331)
                     /locus_tag="CLV43_RS09635"
                     /old_locus_tag="CLV43_102719"
     CDS             complement(14921..15331)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640248.1"
                     /locus_tag="CLV43_RS09635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102719"
                     /product="peptidase inhibitor family I36 protein"
                     /protein_id="WP_106186687.1"
                     /transl_table=11
                     /translation="MSVRKLGQAAFAFVGAAMLVMSGTSAASAAVRDGNCQANEFCYYW
                     YIDATESASDFTGTVQNYGTTQPTCYDFKGPGLGKGECIKNNAMSVWNRTSRTVRVYYN
                     SYLEGSYQDIGAGYKGNLNSTLTNNNASHEFR"
     misc_feature    complement(15347..15361)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.56"
                     /tool="antismash"
     misc_feature    15448..15468
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.12"
                     /tool="antismash"
     misc_feature    15550..15565
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.87"
                     /tool="antismash"
     misc_feature    15560..15573
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.27"
                     /tool="antismash"
     gene            15605..16042
                     /locus_tag="CLV43_RS09640"
                     /old_locus_tag="CLV43_102720"
     CDS             15605..16042
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020644919.1"
                     /locus_tag="CLV43_RS09640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102720"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_106186688.1"
                     /transl_table=11
                     /translation="MPENVGERTLAAKVDHLFRTVHPRTGGEYSFEEVAEAIRAKGGPT
                     ISATYLWQLRKGLRDNPTKRHLEALAGFFGVPPAYFFDDAETERIDSELALLTALRDAP
                     IRQIALRVNGLSPKSLEAITEMVDRVRELEGLPKPTPDTTP"
     misc_feature    complement(15645..15659)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.69"
                     /tool="antismash"
     misc_feature    15646..15660
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.25"
                     /tool="antismash"
     gene            16039..16533
                     /locus_tag="CLV43_RS09645"
                     /old_locus_tag="CLV43_102721"
     CDS             16039..16533
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659610.1"
                     /locus_tag="CLV43_RS09645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102721"
                     /product="hypothetical protein"
                     /protein_id="WP_245886234.1"
                     /transl_table=11
                     /translation="MRPLRGRRLRERCAAVLRDLPLPVPFDAHALCEQVAARRGRPMRL
                     IPMPGLTGVCGMWVATTTADLVFYERETTLPHREHIILHELSHVLCDHYPVSTSLAEQA
                     RLLLPGLDPEVVSRVLGRAGYSSAEEREAETLASLIRQREVPAGSLTDRLRAALDDNGH
                     G"
     misc_feature    16102..16104
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16526..17644
                     /locus_tag="CLV43_RS09650"
                     /old_locus_tag="CLV43_102722"
     CDS             16526..17644
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042915.1"
                     /locus_tag="CLV43_RS09650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102722"
                     /product="MAB_1171c family putative transporter"
                     /protein_id="WP_106186689.1"
                     /transl_table=11
                     /translation="MAELLRQYGPAALAWALVLTRRRHEDGARRSVRWVLLGFAVSLTV
                     LTPAVYAAGAAVGVPDLARLVGHAAMLVVVWAGVEFTARMNGMSRGPRWHARWVVGWFA
                     VMCAMFALAPDLRPQSPWILEYCVVYLVAQGPGLVRIARQCARYAGLTAEPVLRLGLRL
                     IAAGALGSLLYLVHKVLRTAISRFDIAYPLSHAVVTNKVLPTASTVLVLLGAGIPAAAG
                     WARRYRLHRRLGPLWTALYRAEPSIALEPPALPDLLVVRRLRPRLYRRVIEIRDGLLAL
                     QPYRTREVAEAAREHARLTGLTGERSEVAVEAMTVAIALRSRAAGDPPGTPEVPISGGG
                     NLDSDTAFLSEVSAAFRAYEGAVSRSAPGPRV"
     gene            complement(17867..20137)
                     /locus_tag="CLV43_RS09655"
                     /old_locus_tag="CLV43_102723"
     CDS             complement(17867..20137)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227723.1"
                     /locus_tag="CLV43_RS09655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102723"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_106186690.1"
                     /transl_table=11
                     /translation="MELRRPLVVVATSAMVAALFTATTAAQAQPSANAVQTADVMAVQA
                     ASSLVADRPAALHASEADTFVQHEVISSTNGLKYVPYDRTYKGLPVVGGDFVVVTNSTG
                     QVLDTSVAQDTTINLASTTPKVAKADAEATAKAQLPTVDSVGAAQLVTYALGTPALAWQ
                     STVVGRNAEGPSKLDVVVDATTGKVLHTQEHVMRGTGSSAWNGPVTLNTTHVGSTYSLK
                     DPTLTNVSCQDAANNTTFSGTDDAWGNGTATNRETGCVDVLFAAQTESKMLTQWLGRNG
                     FDGSGGGWPMRVGLNDLNAYYDGSQVQIGHNQNNQWIGSLDVVAHELGHGIDDHTPGGI
                     SGSGTQEFVADVFGASTESFANESAPYDVPDFLVGETINLVGSGPIRNMYNPSALGHAN
                     CYSSSVPGSEVHAAAGPGNHWYYLLANGSNPTNGQPTSSTCNSSTVTGVGVETAMKIFY
                     NAMLIKTSGSSYLKYRTWTLTAAKNLFPGSCTEFNKVKAAWDAVSVPAQSADPTCSATG
                     TVTVTSPGNQSTAVGTAVSLPLSASGGTAPYTWSATGLPAGLSISSSTGTISGTPTTAG
                     TSSVTVTANDSASHSGTASFSWTVGTTGGCSGQKLVNPGFESGNTTWASSSGVIGQFGS
                     SGQPTHGGTWNAWMNGYGSTHTDTLSQSVAIPAGCHASLTFYLHIDSAETTTTTAYDKL
                     TVTGGTTTLASYSNLNKASGYVLKTIDVSSFAGSTLALKFSGVEDSSLQTSFVVDDGAI
                     TLS"
     misc_feature    20110..20124
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.86"
                     /tool="antismash"
     misc_feature    20273..20289
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.25"
                     /tool="antismash"
     CDS             20369..20542
                     /gene="allorf_811997_812170"
                     /locus_tag="allorf_811997_812170"
                     /protein_id="allorf_811997_812170"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPGPEDVPGAPENPYKSLPDMGEPIWGLVGSTPARRACTCSSSLD
                     IRQQGQREPRAR"
     CDS_motif       20369..20398
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPGPEDVPGA"
                     /locus_tag="allorf_811997_812170_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       20399..20542
                     /prepeptide="core"
                     /locus_tag="allorf_811997_812170_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.70"
                     /molecular_weight="5040.7"
                     /monoisotopic_mass="5037.6"
                     /core_sequence="PENPYKSLPDMGEPIWGLVGSTPARRACTCSSSLDIRQQGQRE
                     PRAR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPGPEDVPGA"
                     /leader_location="[20368:20398](+)"
                     /alternative_weights="5058.7"
                     /alternative_weights="5076.7"
                     /alternative_weights="5094.7"
                     /alternative_weights="5112.8"
                     /alternative_weights="5130.8"
     misc_feature    complement(20763..20777)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     misc_feature    20764..20778
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     gene            20813..21553
                     /locus_tag="CLV43_RS09660"
                     /old_locus_tag="CLV43_102724"
     CDS             20813..21553
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640099.1"
                     /locus_tag="CLV43_RS09660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102724"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_106186691.1"
                     /transl_table=11
                     /translation="MTSTLSVQLYSVRDAFAADPTDTLRRLAAIGFTQVEPYGVTQNAD
                     VLRKGLPEHGLTAPTAHAQLIGVDQDPVFAVAAECGIGVVIDPYVGAEKWRDPADVAAT
                     ATALNEAAAVAARHGVRVGYHNHWWELESRIDGRSALEVFVDQLDPAVVLEVDTYWATA
                     GGEDAPALLRRLGAKVHAIHVKDGGLATDGTGQLPAGRGVVPVADVLAAAPQALRVIEF
                     DAYDGDVFEGIAASLAYFSDGADR"
     gene            21550..22659
                     /locus_tag="CLV43_RS09665"
                     /old_locus_tag="CLV43_102725"
     CDS             21550..22659
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227639.1"
                     /locus_tag="CLV43_RS09665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102725"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_106186692.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 6.8e-20, bitscore:
                     67.6, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 4.3e-22,
                     bitscore: 74.1, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPLGPVGVGVIGAGVISDTYLENLTGFPDVRVLAVADLDVERA
                     AAQAAKHGVPGSGAVAELLADPAVEIVVNLTIPAAHVEVGLAALDAGKHVWTEKPLALD
                     RESARKLLDRAHDRGLRVASAPDTVLGAGLQTARRAVEAGRIGEPRTALAIFQTPGPER
                     WHPAPEFLFQAGGGPLLDMGPYYLTTLVQLFGPVRRVTATADRARDTRVIAKGPRAGTE
                     FAVTVPTTVMALVEFTGGGSAQLLLSFDAVVARTGLVEVGGTLGTAVLPDPNTFDGSTA
                     LHLTGLDDPETLAPQGHSASRGTGVLELARAIRSGAVERASGELAYHVLDAMLSIDESA
                     ATGRTVDVTSTVDVPPALPEDWDPRTGTL"
ORIGIN
        1 tccccggctg cgcgtccagg atcatggtga gcccggtgcg gacgatctcc tggtcgtcgg
       61 cgacgaccac gcggacgctc accccgccgc cccggccctg ggcagcaccg cggtcacggt
      121 ccagccgcgg tcggggtccg ggcccgcctc gcaggtgccg ccgagcaggc ccgcgcgctc
      181 gatcatgccg atcagcccgt agcccggctc cccggtcggc cgggtggtgg tcgcgtcgcc
      241 gtcgtcgctc acccgcagcc gcaccgacgt gtcgtcggcc gcgaccctga ccacgatccg
      301 ggtcgcgtgc cgggcgtgcc gccgcgcgtt ggtgaccgac tcctgggcga gccggtagat
      361 cgccgtgccg accgtaggcg ggaggtcgtc gacgtcgccg tcgatcccca cgtcgaccga
      421 cggcccggag cgcgacccgc cggtcgcgag ccgttcgagg tcggacacgc gcggggtcgg
      481 cgccagctcg gcctcctggt cctgccgcag gacgtgcacg agggtgcgca tctcgaccag
      541 cgcccgcgac gcctcggcct cgatcagcct cagcgcgtcg accgcggcgt ccgggttcgc
      601 gggcgcggtc gcgaggcccg cctgcgcccg gatcgcgatc gccgagacgt ggtgggcgac
      661 cgtgtcgtgc aggtcccgcg ccagccgccc gcgttcgagc agcttcaccc ggtccagctc
      721 ccgcacccgc gcccccgccc ggtaccgcag cgccgccccg aacgtgaccg ccgagaacgt
      781 caccacgaaa cccgcgcccg cgtcgcccgc gtccacctgc ccgaacacca ccgacagcga
      841 caccttcgcg accacgaccg ccagccccag caccacctcg cgcccggaac cccagcgcgc
      901 caccgagaac accagcagca gcacgaaggc caacgagtac gactccgccg cccgtccccc
      961 ggtcagcagc ggcgacagcc ccgtcacgac gaacgcgacc accagcgcga gcagcggcct
     1021 gctgcgccgc accaacaaca acggcaccag caccagcgcc acaccggtcg cgaccaccgg
     1081 ccaccgcagg tccggccgcc acagcccctc gaccaccacc agcgccgcca gcacccccac
     1141 cagcacccgg tcccgccacc ccaccggcgg caccagggca ggacggggct cgtcccacag
     1201 cgagcgcagc agacctgtca cccgctgatg gtacgagttc cgcccccacc ccggatcagc
     1261 ctggagtacc agacccgccc tggtcggacg gcccctaccg ccacccgccg cggaagaaca
     1321 ccagcggctc ccccgccctc tcccgcgagc accaccgcgg cctgcccagc accagcacgt
     1381 ggtctccccc gaccacgcac cactccacct cgcacaccac cgcggccagc acgtcctcga
     1441 tcaccggcac ccccagttcc cgccggtgcg gcgtgccggc gaagcggtcc cccgtcccca
     1501 cggcgaaccg cttcgccagc tccccctgcc ggtcgtccag cacgttcacc ccgaacacct
     1561 tcgacgccgt gatcgcggcc agcgtgcggc tgccgcgcgc cagcgacacg agcagcagcg
     1621 gcgggtcgag ggagacggag gtgaaggcgt tcacggtgca gccgacggga gccgcaccct
     1681 gggtgctggt gacgacggcg acgccggtgg cccagtcgcg catgaacgag cggaacgcgg
     1741 tgccggtgat ccggtcgagc tcagcggagg tcatcgggcg tccacgagct cgtcgcggca
     1801 cagggaccgc tggcggagca gctcgtcgcg gtcggcaccg gggagcacca gcgcgcgggt
     1861 gtagtcgtcg acggcggcgg ccaggtggcc cgcggcctgg tgcacgaacc ccctgttgta
     1921 cagcaggtcg gggttgtcgg ggtcgacctc gacggcggtg gtgaggtcgc ggatcgccgc
     1981 gtcgtgggca ccgtcgtcgt gggcgagccc ggcgcggtcg gccagcgcgg ccacgaggtg
     2041 gggatcgagc tccagcgcac ggtcgaactc cttccgggcc aggtcccggt cgtcggtctc
     2101 gagggcgagc aggccgttgg cgtgcacgag ccgcgcgtcg gcggggtgca ggcgcaggcc
     2161 ctcggcgagg tggacggcgg cggtgtcgag gtcgccggtg tccagcagca ggctcaccag
     2221 gttgagccgg gcgtcgacct ggtcgggctc caggtcgacc acgtaggcca gctcggcgat
     2281 cgcgccctcc aggtcgccca cctcgaccag gacgtcggcc cggttgtagt gcagctcgta
     2341 gaacggcgcg gtgagggtgg tcgcggtcgc gtagtcgagc agcgcgccct cggggtcgcc
     2401 gagcttgcgc cggacgtcgg cccggtcgaa gtagtagtcc gggtagttgg ggtccagccc
     2461 gatcacggtg tcgaggtcgg ccagcgcctc ctcgtagcgg cccagcgcgc cgaggacctt
     2521 ggagcggttg ttcaccagca ccgagcggtg cagcttgtgc ttgccggggt ccagctcgcg
     2581 gtcgaggcgg gccaggccgt cggtcaccag cttcaacgct cccggcaggt tgtccaggtg
     2641 cgtctcgacg agcgccagcc cgttcttctg gaacacggtc tggaagatcc gctgctcggg
     2701 gtcgggcagc accgaggcga tggccacggc gttgttgagc aggatcttgg cctggtggtg
     2761 gtccttgtgc tccggcgggt ggtggcgggt gtagagcatc gccatcgcgt aggagcagaa
     2821 catgtgcacc atcgggaggg tgtagcggcc gcgcagctcg tcgtagagcg gcaggctctc
     2881 caggctgcgg ttcaacgacg ccagcccggt ggtcatcttc gtcgtcagca gccagtagcg
     2941 ctcctgctgc tcctccgggt cggtgatcgc ccggccgcgc ggcacgtact ccagcagcga
     3001 gtggtagaag cccatgtcga agcagtggtt ggccgcgtcc agcatcgcgt cgccgcccac
     3061 gccggtcggg tcgccaccgt gttcgaggtg gtgcagcagc gcgccgagcc gcaggctcca
     3121 gtcgccgtcg gccagctcgg ccgcccgcgc gtcgtgcagt gccgccacga caacgggatc
     3181 ggcctcggcg taggccgcca gctcgtgcgg gtcgttggag gtgcagtcgc ccgcgacgaa
     3241 ggcgcgcacc agctcctcgg ccggtcgcac gggcccgtcg gcgggcgggt tcaccacgtc
     3301 ctcccggtcc gcgtgggcgc gcagggcctc ggccagctcc tcgacgacgg cgtcggtccg
     3361 ggtgccgacg acgaaccgga cccggcccga ccgggcgcgg cgcaccgcga tggcgaggaa
     3421 ctcctggtcg gtgtggtcgg cctcgtcgac gttggtgaac gacagcacca ggtgccggtc
     3481 ggccagtgcc gcgtaggact ccaggagctc gaccacgccg tgcgccagcc gccgggtgcg
     3541 gttggccggg tagatgcggg tccgctcgct ggggatcgcc accgacgtca gcgtctccgg
     3601 cgcggcgccg atcgcctcgg tcagctccgg ggcggcggac aggatctcga tcgagtgcga
     3661 gcgcaccagg tccggccacc gcgactggac gtcgggcacc agctcgcgca gcagcgtccc
     3721 catcccggtg tacgggccgc gcagccgccg gtgggagtcg acgcggaagt cggcaccgtc
     3781 gtcgtgcgcg gatcgtgggt cgacccgcca caggtgttcg ctcatgtcat tcctctcggg
     3841 tggtcaggtc gacgtgcggt cggtccgacg gtcggtgacg agggtcagga ggacgagctg
     3901 gaccacgatc agcagcacgg cgaccgcgga gtcccagaac ccggcgccgc ccgccgtgcc
     3961 acccgacagg gcggtccaca gccgggcgcc gaactccagc accaccggca cgatcgcgag
     4021 cagcaccgtc accagcagga agacgacacc ggccacggag gtcagcgcga accagggcgc
     4081 cagctgccgg tcgcgcgggg cgaacgcgct gtcgtccact gtggacttcc gcacgaaggg
     4141 cagccggtgg aaccggttgc gcaggtaggc cgaggccgcc tcgtgcaggt tcgtgcagcc
     4201 cgccatcgtg gtcagcacgt agtacaggtc ggtgcgcagg aacaggtagg actgccagac
     4261 cagccgcagc agcaccaggt aggcgatggc gagcgcgagc cgcccgcccc acgccgagtc
     4321 gtcgaccgcg gccacgaggg tcagcgcgct gaacaacagc acgtcggcca ccaccccggc
     4381 gaggaacggc aggtagcgct tggacttcgg gacgctcagc aggccgttga gctcggtctc
     4441 gaagacgatg aagtacagcc tcctgctcac gttcagcttc gacggcacac cgagccgcct
     4501 gcccgcgagc acgtggaacc actcgtggaa cagcacggcg ggcacctgcg tgaacgtcag
     4561 caccacctgc accgcgacca gcgacggcgt gaagaacacg ctggacccgt gcgggcgcag
     4621 ctccggccgg gcgaccatga cgagcaccgc cgcggtcacc agcgccgcgt acccgagcca
     4681 ggcgggcggt gagaacgccg cccgccccaa cgcccggtac cgcaccggcg cgacctcgac
     4741 gacctcaccg tcctcgcgca ggaactccag ctcccgcaac gcctccacga agtcggccat
     4801 gtcgatgggc tcgccgaact ccgcctcgta ccaggcggcc gcctcggcga ccggcatccc
     4861 gtcgaacagc ctgcgcagca gcgccgcgcc gtcctcgggc agcacggcgt aggactcgac
     4921 gtcgaaccgg ccgacggtga ccccgtcccg gtcctggacg aacgtcaggg ggtggaactc
     4981 gaggtggctc gccgacatcg cgcatctccg tgacaggtcg taccggtgca ggccgccccc
     5041 ggttctgggg ctcgggggcg gccgctcacc ggatcagcaa cagggggagc agtagcccgc
     5101 cgcggacgac gtgagcttga tcgaaccggt cttgcggatg gcgatcttct tcatgttctt
     5161 cacctcctga tcggccggcg ggatgggtcg agcagccggc gacggcgacg acgctgccgg
     5221 ccaccggacc ccgtgccatg ggggccgtgc ccccgtgttc ttcgggtgga cgcgcagaag
     5281 atgcgggggc actcccccat ggcacggcgg ccggtcgcgg cagcagggtg gggcgcatgc
     5341 gagacgacgc gctttcgatc atcgtgtccg ggtcgagtgc cgccctgggc atgcccggct
     5401 acctgacgtg gctgcgccag gaggtcgacc tgagcctgcg cgtgctgctc acccgcggcg
     5461 ccgagcggtt cctgcggcgc gaggtgctgg actggtacgc cgaagaggtc tacaccagcg
     5521 acgacccgac cctgaacccg acggagttcg ccaagcggtc actgggcgtc gtggtgctgc
     5581 cctccaccgc gaacatgctg gcagcggccg cactcggcct ggcgggcaca cccgcgcaga
     5641 cggtgctgct ggcgtgcgac gggcccgcgc tgttcttccc gagcatgaac cagacgatgt
     5701 ggaagaagac gtccacgcag cggcacgtga cgacgctgcg ggaggacggg cacacggtcg
     5761 cggagccgca ggagcgggcg gtgttcgagc tgtggcggag ggagaacgcg atggggatcg
     5821 ggatgcctgc gccggatgag gctacggagt tgatcgtggg gtggttggag gggggttcgt
     5881 cttgatggtt tcgttggggc ggggtgcgct gtgtggtcgg gtcggtgtcg ctgcggggga
     5941 cttcgagtgc ggccgacttg acttggggcc ccttttttgg gcttcgtcgg gcgaaaaagg
     6001 gcaggtggta gagcctgccc gccgactcat tgtaagccca aaaaccccaa gtcaagtcgg
     6061 ccgcacgggc ggacgagctt gctcggtttc gttggggttg ggcggtttgc tcggttggtg
     6121 atcggagtgc actttgttct ttcagccctt ccgatcgtcg tcggcgcgcc cgtgggccgt
     6181 tcgcctccgg cctctccttc ggtccgtctg ctcagtccat ccgcacagcc catcccctca
     6241 gcccaccctc acaatccatt ccctcagccc atcccctccg tcccccgtct ccccgtcctc
     6301 ccctccgccc atccctcaat ccattccccc gatcacgtgg tcgatggcga agcggttgag
     6361 ggcggcgcgg tcgggttggg aggttttggc caggaggctg gctacgtgtt tttcgacggt
     6421 gcggggggag atgaagaggc gtttgccgat ttcggtgttg ccgaggcgtt cggccaggag
     6481 gcggaggact tcgtgttcgc ggacggtgac gcccatcgag cggatggggg cggggaggtt
     6541 cgccgtgccg ttgcggtgtt gggtggcgga gacgcccgcg cggcgcagca ggacccggca
     6601 ggcgctggtg atggcgggga cgtcgtcctg gtggaagtag gtctcggctt cgcggagcca
     6661 gttcgcgggg gagccccagg tgtcggagat ggcggcttcg gcggcaaggc ggaggccgag
     6721 gtggcgggcc atggcgaagg gttcggagat ctggaggtgt tcgaccatcg cggcggcggc
     6781 ggccgcggac tggcccgcgc ggccgaggag gacggctttg gcgaggtgga ggaactggcg
     6841 gttccaggcg agggcgccgg ccgggacggc tgccgcctcc tcgtactcgc gccaccccat
     6901 ctcgccgccg aggacgccga gcaggacgcg cagcccgtag cggcccgcca gcacgtagtt
     6961 ggtcgggttc tccgcctcgc tcgcgatcgc gtcgtcgagc gcccgcaccg cctgcggccg
     7021 gttctcctcc agcagggcgc agaacgcctc gcaaagaccg tgcaccaacg gcatctggtg
     7081 cgagtcgcgg ccgtcccacc ggtcgaactc ggcaagcgcg cgggtcatcc cggagcgcct
     7141 gccgcggtgg gcgaacatcg cggccttcgc catcaggacg tagcggatcg agtaccgcag
     7201 ccgcatcctc gtcaccacgg gcacgcagtg gtccgccagc tccgccgccc ggacgaactc
     7261 gccgcgcagc accgcgacca tgaccaggtt gacctcgagc aggtacccct cggtgatcgc
     7321 gccgacctgg aacgcctgca ggtgggcccg ccgcaaccgg gccgcgcggc cggagcgcag
     7381 gttctcgttg acgccggacc gcgcgagcgc gcgcagctgc accgaccgca gccggtgccg
     7441 gtgcgccagc tcggccatgc gcgtgaagta gccgtcggac tcggtgaggt cctgttggcg
     7501 ggtgagggtt cccagcagct ccagcgcctc gcacgcgacc tccggcaggt ccgcctgctc
     7561 cgcgtcgcgc agggcccggc gcaccagtcg ttcggcgacg gtcctgcggt cggcgcccgg
     7621 cgtctccagg gtcaacgtcg ccgcgatcac gtcgacctcg gcggtgagcc gcggcgcgac
     7681 gtccgggccg agcagcgcgc gggtgctggc gatctcctcc gcgccctgcg cccacagtcc
     7741 cgcgcgcacg gccacccgcg ccagcacggt gtgcagcgac gcctgccgct ccacgctcag
     7801 gccggggtcg tccaggtccg gcgccaaggc gagcgcctgc tccacctggc ccgcctcggc
     7861 gagggcgttg agcagcagct ccagcaccgc cacccgttcc tcgtcgtcgt gcgcgagcag
     7921 gtcgtgcgcc cggcgcagca ggtcgacggc ggtggccgcc gccccgtcgg cgagcatccg
     7981 gcggcccgcc tcggcgaaca ggcccgcggc ggtggcgacg tcccctgact ccagccgcag
     8041 gatcgccgcc gacgtgcacc actcgccggg caggccgggg tggtcgacct ccacggcgtc
     8101 ggccgcgcgc cgggccagct cggcccgttc gctcgcgccc agcctggcca gcagcgcgtc
     8161 cgcggtcagc gcgtgccgga acgagtacca ctccggcgcg gggcggtcgg gggtgaccag
     8221 ctgggcctcg accgcggaac gcaggtgccg caacaggtcc gcctgctcca gcccgcacac
     8281 cgcccgcacg accgacagcg ggaaacgacg gcccagcacg gccgcgacgt gcagcagggc
     8341 cgcgacctcg ggagcgagcc ggtcgacccg gtgcgagacg ctgaggacca cggtcaccgg
     8401 caccggtgtg tgcccctcgc cgcgcaccga ccagccgtcc gggtcccgca cgagcccgcc
     8461 cacggcgacc atgctgtcca gcagctcctc gacgacgaac ggcacgccgt cgctgtcgcg
     8521 gaacagccgg tccaccgccg cgccgggcac gtcgtcggac ggcacgccca ggcaggacgc
     8581 aacgagctcc cgcaccccct ccgggtcgag gcgacccggc tcgacgaccg tgacacccga
     8641 ccgccgtccg ccgccccgca ccagctccca ggccggaccg gcctgggagc gggcggtcgt
     8701 cagcagcacg accggctggc cgacgaggtt gtcggcgagg tagtccacga tcgccagcgt
     8761 ctccgcgtcc gcgtcgtgca ggtcctccag gacgatcagg cacccgacgt cccggccgag
     8821 cacggcgagc agccgcagca ggccttcggc gacgacgagc agcgactcgt cgtcgccgaa
     8881 ggccgtggcg tcgcgccatt ccggcaggaa ccgggccagc gacgggcggt agggcaccag
     8941 ctcggggtcg gtgggcagcc cgctctcgcg ggtcagcgag aacagcgcct cggagatcgg
     9001 tcggaacggc gcgggcgcgc cgctcgcgct cgcccgcccc cgcagcaccc gcatcccgcg
     9061 cgacagcgcg tgctcggccg cctcggtgac cagtctggac ttcccgatcc ccgcctcgcc
     9121 gagcacgaac accgtgccgc cccgctgcct cgaaccgtcc tccaccgcgg tggtgagcac
     9181 gcgcgactcc gccgtgcgcc cgaccgtccg cggcgagggg accactaccg ccgtcatgcg
     9241 agccccggct cccgtcaccc gtccgtcagt accggtcgtc cgcgaacgac ccgtacccga
     9301 ggcacgggcc ggacaccgac ggcggtgtga acgtggacag ggtccaggtg tcggccgcgg
     9361 tgacgccgga cgcgcacagc gctccggcac ccgtcggacc ggcgggcgtc agcgccatct
     9421 cccccgccgg atggggtgga caggagtccg gggcgagttt ccaccttgcg tccgggtcct
     9481 tccacaggcg gacggtctcg gcgacgtcga tcgtcggtgc ggtcatggtt tcctccatct
     9541 ccggtcacgc ggacgcgcga cctgcgaacc gggtggccgt ccacccccgg ggattcagcg
     9601 gggcggccgg gctggtcgtc gatccggcgg ggtgtcgcgg cgacgggtgt ccaccactcc
     9661 acctcgcacc ggtccgtcag tccaggtcgt cggtgagccc gtacccgagg cacggggcgg
     9721 acaccgacgg cgtcccgaac gtggtcagcg tcaggaggtc ggccgccacg acgccgtgca
     9781 tgcgcagtgg ccccgcacct tccggggcgg cgggcgtcag catgatctcg cccgccggat
     9841 ggggtggtgc ggacgcccgg tcgagctccc acctggcgtc ggggtccttc cagaggcgga
     9901 cggtctcggc gacgtcgatc gctggtgcgg tcatggtttc ctccttctcc ggccgcgcgg
     9961 gcgcggcctc ggggaccggg tggccgtccc acccggagct tcagcggggc ggacgggccg
    10021 cgcccaggag cagcaccgcc gggacccggt cggggaagcc gagccggagc agtccgtgcc
    10081 cgatcccggc caggccgtcg agcagccccg gcgtgcgcac cgcgtccggg gtgcccgaca
    10141 ccgggccgtc ccggtcgagc gccgccagca ggtcgccgat ccggcgcggt gcctcggccg
    10201 cggcggcctc gtgcccgcgc gccgccgccg cggtgagcag ttccagggtg cccagctcgc
    10261 cgtggcacag gctgtggtcg accgcggccg ggcggcgcag cacgccgtcc acggcccggt
    10321 cgaacgcccc ggccatcagc gggtcccgtt ccagcgccag gacgtcggcg cgggcgagcc
    10381 cgacaccgga ggccccgcgg caccacgtgc cgccgtcggc ctccgcgctg tcggcgagca
    10441 cgggctcgcg gcggcacggg ccgctcgcgg ccacggcgta ccgccacagc gcccacgtcg
    10501 tcccggcgct gccgtgggcg aacccggtcg tcgacggctc gtccgctcgt tccaggagcc
    10561 cggcgcaggc cgtcgccgtg cgccaggcgg agtcgaggcc ggtcgtgcgg tgcaccgcga
    10621 gcatcgcggc gaggcacccg gcggtgccgc ccatcaggtc ggtcgtcccg gcgcggccga
    10681 cgtgcgcggc ggccgcctcc accgccgtgg cggtccagcc gcgcaggtcc gggtcgtcca
    10741 gcagcacggc gaggtgcgag agggcgtagg ccaggccacc caggcccgcg aacccggtgg
    10801 gcatggccgc ctccgcggaa ccgaaccggt ccagcagcga cggcaccgac cgcagcgagc
    10861 gccgtgccac gtccgcgcac cggtcgtcac ccgtgatcgc ggccagctgc ccgaggaaca
    10921 gggccacgcc ggggaaaccg gtagccgggc tcgcgccgag cgggaggacc cgccacgacc
    10981 ggtcgtgctc gaggccgacc cagttgaccc gctcgccgtc gtcgtgcgcg tcggccagca
    11041 ggccgccggc gaccgcgcgc gcggcggcca gcaaccggtc cgggtccggg cgctccgccg
    11101 cgggacgcct gcccggccgc ggtcggggcg agtgggcgcc ccggtcgccg cgggtggcga
    11161 aggacgcgcg gatcacccac tcctgcgtcc gcaggtcggc ctcccccagc gcctcgacct
    11221 tgcgccgcac ccggtccagg ccggtctccc ccagcgcgtc cgggacgcgg accccgtgcg
    11281 cggtgaggat gtcgcgcgag gtgggcgtgg tggtgaacag cgggacgtca cccgcccaga
    11341 ggtcggcgac ctcgtggccg accagccgct cccgcgccgg gtcggcgtcg gaggaccaca
    11401 ggtggccgaa gacgcggtcc cggtcgagcg cgtcgcgcag cacgtcgggg tgggtggact
    11461 cgtcgagcag gcgcacgtac tcggaggtgt cgcgcacgat caccctgacc acgtcggtcg
    11521 cgaacgcgtc cagcggtccg ccgggcgcga gcaggtcggc gcggtgggtc agcacggcct
    11581 cgtaggccgc gcggaagccg gcgacgaggt gctccaggta ctcccccgga tcgacgtcca
    11641 cgccgtcgag gcggagccgg ttctccgctc cgcccagcac ctccggtccg cgcacgagcc
    11701 gcatccggtc ggtgcccgcg ccgtcgaacc cgacgacgtc gtcgggcagc gtcgccccct
    11761 tgtcgccgcc cacgccggag atgtccagca cgccgttcgc gcccgtcatc ggctgcggca
    11821 gcagcgcggt gcgcagcacc gaggcctcca gcgcccgcgc cgcggggtcg tcggccaggt
    11881 cgcgggtcgc ccaggtgggg tggaacagcg tctccacgtc gaccagcacg ggctgctcgc
    11941 cgcacgccac caggttctcg aaatgctggt cggtgacgtc caggacgtgc agcagcgcca
    12001 gcagcgcgcc ctgccggtgg tggaaccgct cgacctgggc ggtgtcggac acctggtggt
    12061 gcgccgcgaa ctccgtccac gcccagtcgc cccggtcgag cacggcgagc gtgcgcgggt
    12121 ccaggcccgg cagcaccgag cccagccacg tgaggacctg gttgaagtgg cggtgcacgg
    12181 ccgaggggcg cggcttgtgg accacgcggg tgccgtcggc gaaaccgagg acggcgaccg
    12241 ccctgccgtc gtggtgggtg tcgcccgcgc cgacgtccac ccgcgccaac gggccggggt
    12301 cgcggccgcc gagcagctcg cggacgatgt cggcgcggtc gtcgacgaac cggtgcagca
    12361 gctcggtgaa cgccgcggcg gtgacgtcgc agtgctgcca cagcaggcgg gccagcacgg
    12421 ggtactcggt cagcagcgcc gtgcggcccg cgcgggtgcc agcgcgccgg gcgaacgccg
    12481 cgaaccgctc ctcgggcgtg tcgccgtcga ggaggccggt caccctggcc acgttgagct
    12541 ccagcacgag gacgcgggtg gaggtccaca ccagggtgcg gcgcagcgcg tcggcgaacc
    12601 ggtccaccac gtcgtcggcg tccacgaaga cgtccggtcc caggtcggcg acctcggccg
    12661 cgacccggcc gcgggcgtcc tgcacgaacg gcttcaccac gaccgcgaac gcgctccgcc
    12721 acgaccggcc gtccaccgcc gcgggcccga ccgcgcggtc caccacgcgc tcgaccccgg
    12781 tcgcccaggc gggtttcggc ccggtcgccg accgctcccc gagcagccgc agcaggtcgt
    12841 cctcgtcgac gccgaccgag gccagccgcc gggtgaagcg gtcgcccgac ccggcgccgt
    12901 gctcggcccg ccagcggtcc agccgggtgc gcgcgcggcg ttcggcgtcc tcggaggcgg
    12961 acgtcccggt cccggccccg gaggccagcc tctcggtcag cgtcctaccg ccgaaccacc
    13021 acccggactc ccacccgccg acatccgcac cagtccgtcc gaccaccacg ccgggcacct
    13081 ccggtccacg gtgactccac tcgtgtacga cagacaggag tggatccaac acccatggat
    13141 acacgcgggc gaacgcaggg ggaatccgcc cgcgctacca ggaggaatgg cgaacccgtt
    13201 ccggtagaac ggtttcggga acgcggccgg caatggcggg atgatcggtc gggcgatcgg
    13261 aaagcgctct ccgcgaaacc gggacgtcac actcggaccg aggaccaccg ggggcgcacc
    13321 cgcggcccgg aaacccgagc cccgatttcc gaaccggcgg cgcggttgaa ccgtattgag
    13381 gacatgggaa cagtgacgcg acgtgcgctg atcaccggcg tcgtggcgct cacggcgctg
    13441 ggggcgggct cggcacgggt ggtggacccg ttcacgctcg gcgtggcctc gggtgacccg
    13501 acgccggacg gggtcgtgct gtggacgcgg ctcgcgccct acccgctggc cgagaacggg
    13561 ctgggcggga tgccgtcgcg ggtggtcgag gtgagctggg agctggcgcg cgacgagcgg
    13621 ttccgccacg tcgtgcggcg cggcaggcag tgggcgcggc ccgagtccgg gttcagcgtg
    13681 cacgtcgagg tcggcggcct ggagcccggc cgggagtact tctaccgctt cgcgaccgga
    13741 ggccacctct cgcggaccgg gcggaccagg acgacaccgg cgccggggac gatgaccacg
    13801 ccgctgacca tggcgttcgc gtcgtgcgcg cagtacgagc acggctactt cacggcctac
    13861 cggcggctcg ccgaggacga gcccgacctg gtgctgcacc tcggcgacta ccagtacgag
    13921 taccgcaagg gcgtgcacgt ggcgcccaac ggcaacgtcc gcgaggtgga cgggccggag
    13981 accgtgacgc tggcggacta ccggcaccgg tacgcgcagt acaagtccga cgccgacctc
    14041 caggcggcgc acgccgccgc gccgtgggcg gtcgtgtggg acgaccacga cgtggccgac
    14101 aactgggcgg gctcccacta cagcaagccc gagatcccgc agcccgactt cccggcccgg
    14161 cgggcggccg cagctcaggc ctactacgag aacatgccga tccggagcaa gccccgcggc
    14221 ttcgacctgc ggctgtaccg gagggtcggc tggggcgggc tcacgacgtt ccacatgctc
    14281 gacacccggc agtaccgcga cgaccagccg tgcggtgacg gcatcaaacc ctgcccggaa
    14341 cggctggagc ccaccaggac gatgctcggc gccgagcagg agaggtggct gctggacggc
    14401 ttccggacct cgtcggcgcg ctgggacgtg ctgggccagc aggtgttctt ctcccagtac
    14461 gaccacaccc ccggccccgt gcaggagacc aacctggacg cctgggacgg ctacgccgcc
    14521 gaccgcgacc gggtcgtcgc cggcttctcc tcggtgcgca acgccgtcgt gctgaccggc
    14581 gacgtgcacg ccgcgtgggg cgcggaggtc aaggagcgct gggacgaccc ggcgtcgcgg
    14641 acggcgggca cggagatcgc ggggacgtcg atcacgtccg gcggcgacgg gtccgaggtc
    14701 tacccggaga cgccggagtg gttcgcggag aacccgcaca tcaagtactt caacaacagg
    14761 cgcggatatg tgcgcacccg tttctcaccc gatgaggtgc gggtggactt ccgcggactc
    14821 gaccacgtct cccgacccgg cgccccggtc tcgaccaaag catccttcgt catcgaggac
    14881 cgggtgccgg gactcaatcc cgtttaacgg gaccggcgcg tcaccggaac tcgtgggacg
    14941 cgttgttgtt cgtgagggtg ctgttcaggt tccccttgta gcccgcgccg atgtcctggt
    15001 aactaccctc caggtaggag ttgtagtaca cgcgcacggt cctggaggtg cggttccaga
    15061 ccgacatggc gttgttcttg atgcactcgc ccttgcccag accaggaccc ttgaagtcgt
    15121 agcacgtcgg ctgcgtcgtg ccgtagttct ggaccgtgcc ggtgaagtcc gacgccgact
    15181 ccgtggcgtc gatgtaccag tagtagcaga actcgttggc ctggcagttc ccgtcgcgca
    15241 ccgccgccga ggcggcggag gtaccggaca tcaccagcat cgcggctccc acgaacgcga
    15301 acgcggcttg accgagcttt cgaacggaca tgttttcctc cccttgtgac aatggaattc
    15361 cacgtgcggg ggaacggctg cccggtcgca cgcggaaacc ccccggcttc gcgtcgatcg
    15421 gaccggcaca ccggtcccct catccccttc tggtccccct gaccatcccc tcccgcgtcg
    15481 actcttcatc tcagttgacg cgatccattc gagcgtaagc tgacatgaac ccagccgtca
    15541 accagggtgg aggagaagca tttttcacat tcatctgagc tggcgcgggc ggtagactcg
    15601 tcgcatgccc gagaacgtcg gcgagcggac cctcgccgcg aaggtggacc acctgttccg
    15661 caccgtccac ccgcgcaccg gcggcgagta ctcgttcgag gaggtcgcgg aggcgatcag
    15721 ggccaagggc ggcccgacca tctcggccac ctacctctgg cagctgcgca agggcctgcg
    15781 cgacaacccg accaagcggc acctcgaagc gctggcgggc ttcttcggcg ttccgcccgc
    15841 gtacttcttc gacgacgccg agaccgagcg catcgactcc gagctggcgc tgctgaccgc
    15901 gttgcgcgac gcgccgatcc ggcagatcgc cctgcgcgtc aacggcctgt cccccaagag
    15961 cctggaggcg atcaccgaga tggtcgaccg ggtgcgggag ctggaaggac tgccgaagcc
    16021 cacgccggac accaccccgt gaggccgctg cgcgggcggc gcctccgcga gcggtgcgcg
    16081 gcggtgctgc gcgacctgcc gttacccgtg ccgttcgacg cccacgcgct gtgcgagcag
    16141 gtcgcggcgc ggcgcggacg gccgatgcgg ttgatcccga tgccggggct gaccggcgtg
    16201 tgcgggatgt gggtcgccac cacgacggcg gacctggtgt tctacgagcg ggagacgacg
    16261 ctcccgcacc gggagcacat catcctgcac gagctgagcc acgtgctgtg cgaccactac
    16321 ccggtgtcga cgagcctcgc cgagcaggcc cggctgctgc tgccgggcct ggacccggag
    16381 gtggtgagcc gggtgctggg tcgggcgggg tactcgagcg cggaggagcg ggaggcggag
    16441 acgctggcgt cgctgatccg gcagcgggag gtgcccgccg gttcgctgac cgaccggctg
    16501 cgggcggcgt tggacgacaa cggtcatggc tgagctgctg cgccagtacg ggcccgccgc
    16561 gctggcgtgg gcgctggtcc tgacccggcg caggcacgag gacggggcgc gccggtcggt
    16621 gcggtgggtg ctgctggggt tcgcggtgtc gctgaccgtc ctcaccccgg cggtgtacgc
    16681 ggcgggtgcg gcggtcggcg ttccggatct ggcccgcctg gtcgggcacg cggcgatgct
    16741 ggtcgtggtg tgggcgggcg tggagttcac ggcccggatg aacgggatga gccgcggtcc
    16801 gcggtggcac gcccggtggg tcgtcggctg gttcgcggtg atgtgcgcga tgttcgcgct
    16861 cgcgcccgac ctcaggccgc agtcgccgtg gatcctggag tactgcgtcg tgtacctggt
    16921 ggcgcagggg ccgggactgg tgcggatcgc ccggcagtgc gcgcgctacg ccgggttgac
    16981 ggcggaaccg gtgctgcgac tgggcttgcg cctgatcgcc gcgggcgcgc tggggtcgct
    17041 gctctacctg gtgcacaagg tgctgcggac ggcgatctcc cggttcgaca tcgcctaccc
    17101 gctcagccac gccgtggtga cgaacaaggt gctgccgacc gcctcgaccg tgctggtgct
    17161 gctgggggcc ggtatccccg ccgccgcggg gtgggcgcgc cgctaccggc tgcaccggcg
    17221 gctcggtcca ctgtggacgg cgctgtaccg ggccgagccc tcgatcgccc tcgaaccgcc
    17281 tgccctgccg gacctgctgg tggtgcggcg actgcggccg cggctgtacc ggcgggtgat
    17341 cgagatccgc gacgggctgc tggcgttgca gccgtaccgg acgcgcgagg tggccgaggc
    17401 ggcgcgcgag cacgcccggc tgaccggcct gaccggggag cggtctgagg tcgccgtcga
    17461 ggcgatgacc gtggccatcg ccctgcggtc ccgtgccgcg ggtgacccgc ccggcacacc
    17521 ggaggtgccg atctccgggg gcgggaacct ggacagcgac accgcgttcc tgagcgaggt
    17581 gtcggcggcc ttccgggcct acgagggagc ggtctcgcgt tccgcgccag ggccgcgggt
    17641 ctagggcgtg tgtcgaagtc tcgttcgatg ggagtcgcgc ctgaggtggt tcctggcggt
    17701 gcggccgact ggcccgcata ccgctgttgt atgcgggcca gtcggccgtg cccccagggg
    17761 ccgcctcagg cccggctacc gcgaacacgg acttcgacac acgccctagg gcgcggcgga
    17821 ggggaggccg ggtgtcccgg cctcccctcc gtcacctgtc agtcggtcag ctcagcgtga
    17881 tcgcaccgtc gtcgacgacg aaggacgtct gcagcgagct gtcctcgacg ccgctgaact
    17941 tcagcgcgag ggtcgaaccg gcgaacgagg acacgtcgat ggtcttgagg acgtacccgc
    18001 tggccttgtt gaggttggag taggaggcga gggtggtcgt gccgccggtg acggtgagct
    18061 tgtcgtaggc ggtcgtggtg gtggtctcgg cggagtcgat gtgcaggtag aaggtcaggc
    18121 tggcgtggca gcccgccggg atggccaccg actgggagag cgtgtcggtg tgggtggagc
    18181 cgtagccgtt catccaggcg ttccaggtgc cgccgtgggt cggctggccg ctggagccga
    18241 actggccgat gacaccgctg gaggaggccc aggtggtgtt gccggactcg aagccggggt
    18301 tgaccagctt ctggcccgag cagccgccgg tggtgccgac cgtccagctg aacgacgccg
    18361 tgccgctgtg cgaggcggag tcgttcgcgg tcaccgtgac gctggaggtg cccgcggtgg
    18421 tcggggtgcc ggagatggtg ccggtggagg agctgatgga caggccggcg ggcaggccgg
    18481 tcgcggacca ggtgtacggc gcggtgccgc cgctggccga gaggggcagg ctgacggcgg
    18541 tgccgacggc ggtggactgg ttgccggggc tggtcaccgt gacggtgccg gtggccgagc
    18601 aggtcgggtc ggcggactgg gcgggcacgc tgacggcgtc ccaggcggcc ttgaccttgt
    18661 tgaactcggt gcagctgccg gggaagaggt tcttcgcggc ggtcagcgtc caggtgcggt
    18721 acttcaggta cgagctgccg gaggtcttga tcagcatcgc gttgtagaag atcttcatcg
    18781 cggtctcgac gccgacaccg gtcaccgtgg agctgttgca ggtggagctg gtcggctgcc
    18841 cgttggtcgg gttggagccg ttggccagca ggtagtacca gtggttgccg ggacccgcgg
    18901 ccgcgtggac ctcggagccg gggaccgagc tggagtagca gttggcgtgc ccgagcgcgg
    18961 aggggttgta catgttgcgg atcgggccgc tgccgacgag gttgatggtc tcgccgacca
    19021 ggaagtccgg cacgtcgtag ggggcggact cgttcgcgaa ggactctgtc gaggcgccga
    19081 agacgtccgc gacgaactcc tgcgtgccgc tgcccgagat gccaccgggg gtgtggtcgt
    19141 cgatgccgtg gccgagctcg tgcgccacga cgtcgaggga gccgatccac tggttgttct
    19201 ggttgtggcc gatctggacc tggctgccgt cgtagtaggc gttcaggtcg ttgaggccga
    19261 cgcgcatcgg ccagccgccg cccgagccgt cgaagccgtt gcggcccaac cactgggtga
    19321 gcatcttgct ctcggtctgc gcggcgaaca ggacgtcgac gcagccggtc tcgcggttgg
    19381 tcgcggtgcc gttgccccac gcgtcgtcgg tgccgctgaa cgtcgtgttg ttcgcggcgt
    19441 cctggcagct gacgttggtc agcgtcgggt ccttcaggga gtacgtggag ccgacgtgcg
    19501 tggtgttcag cgtgaccggg ccgttccagg cgctggaacc cgtgccgcgc atgacgtgct
    19561 cctgcgtgtg gagcaccttg ccggtcgtgg cgtccacgac gacgtcgagc ttgctcgggc
    19621 cctcggcgtt gcggccgacg accgtgctct gccacgcgag cgcgggcgtg ccgagcgcgt
    19681 aggtgacgag ctgggcggcg ccgacgctgt ccacggtggg cagctgggcc ttggccgtgg
    19741 cctcggcgtc ggccttggcc accttgggcg tggtgctggc caggttgatc gtggtgtcct
    19801 gcgcgaccga ggtgtcgagc acctggccgg tcgagttcgt gacgacgacg aagtcgccgc
    19861 cgacgaccgg gaggcccttg taggtgcggt cgtacgggac gtacttcagg ccgttcgtgg
    19921 aggagatcac ctcgtgctgc acgaaggtgt ccgcctcgct ggcgtgcagc gcggccgggc
    19981 ggtcggcgac gaggctcgac gcggcctgca cggccatcac gtcggcggtc tggaccgcgt
    20041 tggcggacgg ctgcgcctgg gcggcggtcg tcgcggtgaa cagggcggcg accatcgcac
    20101 tggtcgcgac cacgacaagt gggcgtctca gttccatcgg tgaaactcct ccgggcaggg
    20161 cgaacacgac cccgtgcagt cagggagggt cgtgtccggg ttagaggtga aagtgttgcc
    20221 acgaacggaa acaggatccg tccgcggcta ccggcgaatc aacagacgtc cgtcctaact
    20281 tattaacagc aattttcacg accagtttcc cgacgtcggg aaggcatgcc ggagcggacc
    20341 gcccgttccg cgacggcctc gaccggtcat gcctggtcca gaggatgtcc ccggcgcacc
    20401 ggagaacccc tacaaatccc tcccggacat gggggaaccc atctgggggc tcgtcgggtc
    20461 aacaccggcc cgacgagcgt gtacctgttc ttcctctttg gatatacgcc aacaggggca
    20521 acgcgaaccg cgagcgcggt gaaccattcc ggcaacgagt acaaagggtc gaaaaaggac
    20581 aagatgccat ccgtaggcgg tatgggaaaa ccgactggac cactgctccg gtgatggccc
    20641 gacagcaccg acgaccgatc ccggaacacg actggaacca ggtcccgcaa cagggccccg
    20701 ttaccggcga accggtctcc cggtgaaccc ctggtgacaa attctaccgc gtggtagaaa
    20761 ttgtgggagc gctcccacgc gctgctccac cttcgacttc agggagctgg ggatgacgag
    20821 cacactctcc gtgcagctgt actccgtccg cgacgccttc gccgccgacc cgaccgacac
    20881 cctgcggcgg ctcgccgcga tcggcttcac gcaggtggag ccgtacggcg tcacgcagaa
    20941 cgccgacgtc ctgcgcaagg gcctgcccga gcacggcctg accgcgccca ccgcgcacgc
    21001 tcagctcatc ggcgtcgacc aggacccggt cttcgcggtg gccgccgagt gcggcatcgg
    21061 cgtcgtcatc gacccctacg tcggagccga gaagtggcgc gacccggccg acgtcgccgc
    21121 gacggcgacc gccctcaacg aggccgccgc ggtcgcggcc cggcatggcg tgcgggtcgg
    21181 ctaccacaac cactggtggg agctggagtc ccggatcgac gggcgcagcg cgttggaggt
    21241 gttcgtcgac cagctcgacc ccgccgtcgt gctggaggtc gacacctact gggccaccgc
    21301 gggtggcgag gacgcccccg cgctgctgcg ccgactcggt gcgaaggtgc acgcgatcca
    21361 cgtcaaggac ggcggtctgg cgaccgacgg caccggccag ctcccggcgg gccggggcgt
    21421 ggtgcccgtg gccgacgtcc tcgccgcggc gccccaggcg ctgcgcgtga tcgagttcga
    21481 cgcctacgac ggcgacgtgt tcgagggcat cgccgccagc ctcgcgtact tctccgacgg
    21541 ggccgaccgg tgagcgcgcc gctcggtccg gtcggcgtcg gcgtcatcgg cgcgggggtc
    21601 atcagcgaca cgtacctgga gaacctcacc ggcttccccg acgtgcgggt gctggccgtc
    21661 gccgacctgg acgtggagcg ggcggccgcc caggccgcga agcacggcgt gcccgggtcg
    21721 ggcgcggtgg ccgagctgct ggccgacccg gcggtcgaga tcgtggtcaa cctgacgatc
    21781 ccggccgcgc acgtcgaggt cggcctcgcc gcgctggacg cgggcaagca cgtgtggacg
    21841 gagaaacccc tggcgctgga ccgggagtcg gcgcgcaagc tgctcgaccg cgcgcacgac
    21901 cgggggctgc gggtggcgag cgcgccggac acggtgctcg gagcggggtt gcagaccgcg
    21961 cggcgggccg tggaggcggg gcggatcggc gagccgcgca ccgcgttggc gatcttccag
    22021 acgccggggc cggagcggtg gcacccggcg ccggagttcc tgttccaggc gggcggcgga
    22081 ccgctgctgg acatggggcc gtactacctg acgacgctgg tccagctgtt cggtccggtc
    22141 cggcgggtca ccgccaccgc ggaccgggcg cgcgacacca gggtgatcgc caagggtccg
    22201 cgcgcgggca cggagttcgc ggtgaccgtg ccgacgacgg tcatggcgtt ggtggagttc
    22261 accggcggcg gttcggcgca gctgctgctg agcttcgacg ccgtggtggc gcgcacgggt
    22321 ctcgtcgagg tcgggggcac gctcggcacg gccgtgctgc cggacccgaa cactttcgac
    22381 gggtccaccg cgctgcacct gaccggcctg gacgacccgg aaacgctggc gccgcaaggg
    22441 cattcggcct cccgcggcac cggcgtgctg gagctggctc gcgcgatccg gtccggcgcg
    22501 gtggaacgcg cgtccggcga gctggcctac cacgtgctcg acgcgatgct gtcgatcgac
    22561 gagtcggccg cgaccgggcg gacggtggac gtgacgagca ccgtggacgt gccgcccgcg
    22621 ctgccggagg actgggaccc gcgcaccggc acgctctgac cgcgcgaacc ggaggcccgc
    22681 ccgacggcgg gcctccgtcc actttcgctc ccgaagtcgc acggtgcggg gatcatcgga
    22741 ggaatcccgt gcacgccaac gccttcccgg ccgagggcgt ggtggcggtc cagttcggtg
    22801 agcagcggca acgggcaccg aacaatttcg acgtgccggc cgaaactccg ccgcgtgccg
    22861 ctacggtcgt cgaatgccgc ccggtcgtag ggtggtcgcg acaaaggggg gcccgagtgc
    22921 gtggactggc cgggcggtcg aggtcggtgg atccggacgc gggggcggcg gcgcaggtcg
    22981 ccgcccactt cgacgcgctc gtcgaggcgg gtgccggacc ggagaaggcg gtgagagcgg
    23041 cggccgtgct cgcgggctgt cccgccggg
//
