LOCUS       NZ_PVTF01000002        21116 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Umezawaea tangerina strain DSM 44720 Ga0180964_102, whole genome
            shotgun sequence.
ACCESSION   NZ_PVTF01000002
VERSION     NZ_PVTF01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Umezawaea tangerina
  ORGANISM  Umezawaea tangerina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Umezawaea.
REFERENCE   1  (bases 1 to 938859)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 938859)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Expected Final Version            :: No
            Genome Coverage                   :: 86.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003002815.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:47:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,483
            CDSs (total)                      :: 9,418
            Genes (coding)                    :: 9,322
            CDSs (with protein)               :: 9,322
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 20 of 97
            Pseudo Genes (incomplete)         :: 83 of 97
            Pseudo Genes (internal stop)      :: 2 of 97
            Pseudo Genes (multiple problems)  :: 8 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 234920
            Orig. end                         :: 256036
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVTF01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21116
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21116
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21116
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11116](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11116
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            1132..1764
                     /locus_tag="CLV43_RS07150"
                     /old_locus_tag="CLV43_102220"
     CDS             1132..1764
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005459940.1"
                     /locus_tag="CLV43_RS07150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102220"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_106186261.1"
                     /transl_table=11
                     /translation="MAVDPAMPLRADARRNRDQIIAAARTIFVDQGPDAPMEDIARAAG
                     VGVGTLYRRFPDRGTLIREVAVDSFGRALTEARASIEEEPTCWDALVRFIGFSQELRLS
                     LHLAMISAQAGAVIRDDPATDEFRRVLLTDLDHMVKGAQAEGKVRTDIGTGDVAMLFVL
                     LMRPLPAKLDEIEGASERCMTLMLDGLRAHPGTPLPSRPITYEDLLD"
     misc_feature    1823..1837
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.31"
                     /tool="antismash"
     gene            1855..3114
                     /locus_tag="CLV43_RS07155"
                     /old_locus_tag="CLV43_102221"
     CDS             1855..3114
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099860.1"
                     /locus_tag="CLV43_RS07155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102221"
                     /product="DUF1800 domain-containing protein"
                     /protein_id="WP_106186262.1"
                     /transl_table=11
                     /translation="MADLDDRALARRLHDRFGFGPRPGDLDRGADDALGRLLTAAPAAT
                     PALQLAPPAAPTKDKQAKQDANAARAADEKKLLSWWLGRMVATDTAQERLTWFWHGHFA
                     TSEQKVRSPFHMLGQNEAFRRLGAGDFGELAKALVVDPALILWLDGNDNRSGAPNENLA
                     REFMELFTLGIGHYSETDVREAARALTGWTVKRDSAQAVLTAKRHDDKPQTVLGVTSSF
                     TAASFVDTVLAKPESAAFVVGRLWFRLVSATPPAPDAVDRLVAAYGAKRDVTAVLRAIA
                     AEPAFRSADTTLVKQPVEWVVGLMRALDVRWESLDDKAVKQLGTGLRGMGQVPLRPPSV
                     GGWAAGGAWLTTAAGVARLTVARLLAARTASKPADAEAARVLLSVDAWSDRTRDALAKV
                     DKPEDVIAVAACAPEYVVSR"
     gene            3111..4355
                     /locus_tag="CLV43_RS07160"
                     /old_locus_tag="CLV43_102222"
     CDS             3111..4355
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659663.1"
                     /locus_tag="CLV43_RS07160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102222"
                     /product="DUF1501 domain-containing protein"
                     /protein_id="WP_106186263.1"
                     /transl_table=11
                     /translation="MTAKLTRRHFLTLSGVTAAGALAYGATRVDWDDLLSAAADSPLAS
                     GAGVLVVVTLYGGNDGLNTVVPAADSAYQDARPDLAYRPEEVLDLGDGLGLNPGLKGLK
                     GLWDEKGLAVVRGVGYPTPDHSHFRSMAIWQTASPRTSVPTGWLGRWLDTTGADPLRAL
                     SVEPVLPPMLAGAKTAAASLPLGGLKLPTGKLGEAFQALGTPSAGEEPWQARAAKSITD
                     LHSAARILGGAVHDAAEDDPDEKRDKGASAGGASALGAQLDAVAALIEAEVPTRAYSVS
                     LGGFDTHADERDTQQRLLTELDTALTAFAKRLKGTDRGRQAVVLVYSEFGRRVHANASD
                     GTDHGTAGPVFLLGAPVKGGFFGDQPSLTDLDNGDLKQTTDFRDIYATVLQDVLDTDPG
                     KVIEDHRGRIDGLLL"
     gene            4563..4808
                     /locus_tag="CLV43_RS47640"
     CDS             4563..4808
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV43_RS47640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_170155725.1"
                     /transl_table=11
                     /translation="MDSPSRGRREQPTRIPRKIPAGNRFVPVSDPARATMTISVGNQVQ
                     LNGPHSTTVEQPTLSAYRDALGGLLKPRVTARPRST"
     gene            4874..5638
                     /locus_tag="CLV43_RS07165"
                     /old_locus_tag="CLV43_102223"
     CDS             4874..5638
                     /GO_function="GO:0015485 - cholesterol binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013457.4"
                     /locus_tag="CLV43_RS07165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102223"
                     /product="thiol-activated cytolysin family protein"
                     /protein_id="WP_170155726.1"
                     /transl_table=11
                     /translation="MSYGRTAFIVYESEYSSQEVEAALRVSATARLGPIPVGAGVEPKW
                     WSADTLGKSSFTGYVLGGSGPDAVRASRGLDDVQAYITGGGNYSAESPGAPIAYSLSNL
                     GDNAMAGAGRTVDYPVRRCERIRGRVAVKLKQVKVDSEDDVDLCGSISAWHGTTRVSLF
                     DRDCKDGHKVTVEHEHPWEPGVQEPLEVTTRDGQSIDLHVRLVESNTLFPDQEIEYRVV
                     NKRYEDGWRDVAEVKLSREDTSVTVVVELIPT"
     gene            complement(5666..6583)
                     /locus_tag="CLV43_RS07170"
                     /old_locus_tag="CLV43_102224"
     CDS             complement(5666..6583)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1125: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="CLV43_RS07170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102224"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_170155727.1"
                     /transl_table=11
                     /translation="MATDWGRLDLNLLIPLNALLLERNVTKAADRLVMGQPAMSAALAK
                     LRRHFDDPLLVREGRAMVLTPFAESLVGPVQTALVAAREVLSSGRSFTPATDRRTFTLM
                     ASDYVAGVLVLPALRGLATDAPGVRVTVASLRADLVELLRTGWCDVLFWPLQLQTPELL
                     NFPHVPVFTDEFVAAADRDNHGLPEPLTAEALTTTRAVQVNGIAGQRVVSAVKLAELGV
                     TTPSPVTVESFTLALQAVAGSDLVTLTPRRLFDHLGPALGLREVPLAVERPRMTIGMFW
                     HPRNMLVPAHQWMRERLAAAGEGL"
     gene            6810..7253
                     /locus_tag="CLV43_RS07175"
                     /old_locus_tag="CLV43_102225"
     CDS             6810..7253
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039977.3"
                     /locus_tag="CLV43_RS07175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102225"
                     /product="DUF6069 family protein"
                     /protein_id="WP_146174674.1"
                     /transl_table=11
                     /translation="MTDTSDLPSHARQPAIASGRAAVGVALAAIASVALNTVIAVLANA
                     ALPAEGVRKGLTLKEYAPLTVVGILLGTLAWYLVRRSARDPRAVLRVLVPAAVLVSLVP
                     DFGILAAGVHLLNSLALVTMHLVVAAITVPVLVKVLPLPHSRS"
     misc_feature    complement(7514..7524)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(7538..7554)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.79"
                     /tool="antismash"
     misc_feature    7586..7601
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     gene            7630..9042
                     /locus_tag="CLV43_RS07180"
                     /old_locus_tag="CLV43_102226"
     CDS             7630..9042
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225101.1"
                     /locus_tag="CLV43_RS07180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102226"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_245886201.1"
                     /transl_table=11
                     /translation="MTATESDTTSPGAASLLSSLSRAAARNLATTTKSVPQMQGISSRW
                     LLKLLEWKQVDGGTYRVNRRLSHAVGDGRVTFEQTGSAVRVVPAELAELAPLRGYADTA
                     VLAELARRFARVEFAPGDVLAGFGHRADRVVLVAHGKIAKSGPGAYGDETSLGVLKDGD
                     HFGAQALLSADGISEFTAKAITAGTALTLSRDDFEAVLRRSGSLRAQLDRASEVRAAAN
                     EHGESEIDIASGHGGEPPLPTTFVDYEGSPREYGLSVAQTVLRVHTRVADLYNQPMDQV
                     EQQLRLTIEALRERQEHELVNNPDFGLLHNADFAQRVATRTGPPTPADFDELLSLVSKE
                     PGFFLAHPRTIAAFFRECTKAGVYPSDPGPDGGDRISWRGVPIYPCGKIPVSAGRTSSV
                     LLMRTGEDNRGVLGLRQVGLPDEYEPGLSVRRMGVSDRAITSYLVSTYYSAAVLVPDAL
                     AVLEGAEVSREG"
     gene            9098..9958
                     /locus_tag="CLV43_RS07185"
                     /old_locus_tag="CLV43_102227"
     CDS             9098..9958
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032723.1"
                     /locus_tag="CLV43_RS07185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102227"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_106186268.1"
                     /transl_table=11
                     /translation="MTAVSTAPADVLRTAYQKSVASYWNAEQDPVNLRLGDVDGLYHHH
                     YGIGEVDLSVLEGPQDTRDAQIIAEMHRLETAQADVLLDHLGDIRPQDRLLDAGCGRGG
                     TSIMAHERFGCEVDGVSISQKQVDFANRQAAVRGAEGKVRYHFRNMLDTGFESGSRRAI
                     WNNESTMYVDLFELFAEHARQLEFGGRYVTITGCYNDVTGGRSKAVAQIDQHYTCNIHP
                     RSAYFKAMTANGLVPISVVDLTAQTIPYWELRAKSSVATGIEDPFLTAYREGSFHYLLI
                     AADRI"
     gene            10001..11116
                     /locus_tag="CLV43_RS07190"
                     /old_locus_tag="CLV43_102228"
     CDS             10001..11116
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159832.1"
                     /locus_tag="CLV43_RS07190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102228"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_106186269.1"
                     /sec_met_domain="T1TS (E-value: 1.2e-56, bitscore: 188.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDLQHTTSTFTGLGTSAARFAARLGSGREQGSPDPENGNDPAYA
                     HRPWGDGSASPLYCPLPERIDDTLAQEVDRRLALWARDCGFSAEEAEQLGQAEFGRLVV
                     LAHPDCDDPDRLLISARLNAAWWAADDLYADDTALGAVPAELPQRLALAMAAMDPLPTA
                     GSFSDELDEALGGDKVLVALRSGMEHLAGYGTPAQFQRVCYSTFAMFVSWTAYGAWKHN
                     DRTPPAWEYLAARQHDSFYTSMTLIDVLGGYELDSNLFYEPEVRGAAILAGTASVLVND
                     LFSVTKDLADENPPCNMVLQVAADRECSVPEAVEAVVELHNGLVRDFQDVYRKTRFVPS
                     PQLRRFMRGLRAWMGGGFEWHSTSPRYRTPS"
     gene            complement(11184..12896)
                     /locus_tag="CLV43_RS07195"
                     /old_locus_tag="CLV43_102229"
     CDS             complement(11184..12896)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803072.1"
                     /locus_tag="CLV43_RS07195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102229"
                     /product="FAD-binding dehydrogenase"
                     /protein_id="WP_211304303.1"
                     /sec_met_domain="DAO (E-value: 7.7e-08, bitscore: 27.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTLGLGQASAAPRVDADVIVVGSGLAGLVATSELAAAGRKVLLL
                     DQEPEASLGGQAFWSLGGLFFVDSAEQRLAGIKDSLDLARGDWFNTAGFDRGVDTPLGE
                     DYWAAKWAEKYLEFAAGEKRSWLSGLGVSWVPIVGWAERGGQHADGPGNSVPRFHLTLG
                     TGPGVVEPFEKLVRAAAARGTVTFRFRHQVDGLITTNGAVTGVRGSVLQPSSAARGTPS
                     SRTKVGDFELYAPMVVVTSGGIGGNQDLVRRNWPARLGTPPARMVTGVPAHVDGRMLAI
                     SELAGARLVNRDRMWHYTEGLTNHTPIWSGHGIRVLAAPSSMWFDAEGRRLANPGVPSY
                     DTLGTLELIQRSGHGYSWFVLNKKIIDKEFVLSGSEQNPELTRKDLLGYLASRLLNSTP
                     PPVKAFMDRGEDFVVANSLADLVAGMNRIAGGNLVDLDALRRQITLRDQQVDNPFTKDT
                     QIMGIRNSLAYSGDQLARTAPLHKILDSSAGPLVAIRMNILTRKTLGGLQTDLSGRVLG
                     STGQPIPGLYAAGEVAGFGGGGVHGYRALEGTFLGGCLFTGRQTGRAAAAESA"
     misc_feature    complement(12999..13013)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     gene            13160..14302
                     /locus_tag="CLV43_RS07200"
                     /old_locus_tag="CLV43_102230"
     CDS             13160..14302
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014467087.1"
                     /locus_tag="CLV43_RS07200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102230"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_106186798.1"
                     /transl_table=11
                     /translation="MTAVALRVMAAMAADDQVVTRVVGAARENSPEVARLPEAENRRHI
                     ATLLTAGAAHLRGGDGDFSAAEALGADRAAQGVSIAGLLRGVHAGRAEVIRAGVEFARA
                     TGVDDSTILDFIVDVDSYVAAVERHIISSYHTAELQLSRTARDLNTQVLRGLLVPDGAF
                     PDAAELGRVGLRPESRYHCVVSDVTDPSRARSLEQRWQRSGGVYGLVEGRLTGVGPHPP
                     CGPDDDAPLLVTSPAAPLTSLRGMYPLCVQALAVASARRARGTHPLTDLAAETALAAHP
                     ALAATLTDDLLRPLDPKSGFHHELVTTALCYLDHGRRIGTAAAVLHIHPNTVRYRLDRL
                     AELTDVDLNGVAHPHRSHVLTTVHTWWALRTWLDRGAKGR"
     gene            complement(14306..15229)
                     /locus_tag="CLV43_RS07205"
                     /old_locus_tag="CLV43_102231"
     CDS             complement(14306..15229)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495612.1"
                     /locus_tag="CLV43_RS07205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102231"
                     /product="NmrA/HSCARG family protein"
                     /protein_id="WP_106186271.1"
                     /transl_table=11
                     /translation="MSTDSAPVLVTGATGRQGGATARALIAAGIPVRALVRDPASDRAE
                     AVRALGAELVVGDLGDRDSVALAAKGARAVFSVQMPPFTGEGFDFDGEVAQGTNLVEGA
                     KAAGVPQFVHTSVTGAGRHREGPQWTESRWSSMTRSMDAKAAVQDRVREAGFEHWTILK
                     PGFFMENFLPSMGFLFPRGVEGGLVSVLKPGTRLSLAAVEDIGRAAAAAIADPVRFDGV
                     ELEFASDHLSMAEIAEVLSRVLGTPLAAPDMTEEQALAAGMPPMGASHERLNTTGQPAR
                     PEYGRELGIPLTGFETWARENWRADA"
     misc_feature    15274..15287
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            complement(15324..16211)
                     /locus_tag="CLV43_RS07210"
                     /old_locus_tag="CLV43_102232"
     CDS             complement(15324..16211)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF017206.4"
                     /locus_tag="CLV43_RS07210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102232"
                     /product="NmrA family NAD(P)-binding protein"
                     /protein_id="WP_170155728.1"
                     /transl_table=11
                     /translation="MSALLLGATGNIGPHVVSSLLEGGTEVRVLARDADRARSVLPDAV
                     EVVGWDPLDEKGLLAAAEGVESLLLLSPHGLDMADTQQRVLRTLRGAPLRVVKLSATST
                     SVVPDGPLVGRQHWEVEQVLRAGGQPFVVLRPNGFGQVIVNQAVAGALRTTGVLPNPLG
                     TAAISLVDARDVGAVAARALTSDAWDGRTLVLTGPRAVTYQELADLVSAGTGTPVTVVD
                     VGLDAVRDSLVGRGLPEWEVRHVGEMYELFRGGASAFVTDDIRQVLGVEPRGVEVCVAE
                     AVTAGAFTHGSMVS"
     gene            complement(16311..18266)
                     /locus_tag="CLV43_RS07215"
                     /old_locus_tag="CLV43_102233"
     CDS             complement(16311..18266)
                     /EC_number="6.2.1.16"
                     /GO_function="GO:0030729 - acetoacetate-CoA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (94-516). E-value: 5.8e-55.
                     Score: 178.4. Matches aSDomain:
                     nrpspksdomains_CLV43_RS07215_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF002937.0"
                     /locus_tag="CLV43_RS07215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102233"
                     /product="acetoacetate--CoA ligase"
                     /protein_id="WP_106186273.1"
                     /sec_met_domain="AMP-binding (E-value: 1e-61, bitscore:
                     204.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAGPVWRPDPDPDASIIRFTCRAEAVTGRSMADYRELWKWSVED
                     LEGFWGEVWEYFDVRSDNGFDRVLDDEPMPGARWFPGARLNYAEHVLRGGGDGPALIAV
                     TEDGTTTSVDWPELRSRVAAFAGWLRGQGVGPGDRVVGYLPNAAPAVVAFLATASLGAV
                     WSVCGQDYGADGAAARFGQLAPTVLVAADGYRFNGRVHDRRAAAARLRDLLPTLRATVL
                     VDHVGTSGDPTMVPWAEAVATPAPPAFERVDFDAPLWVLFSSGTTGAPKGIVHGHGGVL
                     LEHLKLMGLHNDLRPGERFFWYTTTNWMMWNLVVSGLLVDATVVLYDGSPVFPGPDRLW
                     RLAEEHRVSVLGVSPGYLLACAKAGVEPSALDLGALRVVGSTGAPLPVSCYSWVSEHVG
                     PSVQLVSTSGGTDVVSGFAGSAPTTPVWPGEISAPMLGVALEAWDADGKPVVDEVGELV
                     VTRPMPSMPVAFWDDPDGTRYREAYFATYPGVWRHGDWMTVTGRGGVVISGRSDSTLNR
                     HGVRLGSADVYAVVEKLPGIREALVIGAELADGGYWMPLFVVLEDGVVLDGPLRDRITA
                     AIRAEASPRHVPDDVIAVPGIPHTRTGKKLEVPVKRLLQGVPVERALDRGAVDDPALLD
                     FYARLARNPASGAAES"
     aSDomain        complement(16719..17984)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLV43_RS07215_AMP-binding.1"
                     /evalue="5.80E-55"
                     /label="CLV43_RS07215_AMP-binding.1"
                     /locus_tag="CLV43_RS07215"
                     /protein_end="516"
                     /protein_start="94"
                     /score="178.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="GGDGPALIAVTEDGTTTSVDWPELRSRVAAFAGWLRGQGVGPGDR
                     VVGYLPNAAPAVVAFLATASLGAVWSVCGQDYGADGAAARFGQLAPTVLVAADGYRFNG
                     RVHDRRAAAARLRDLLPTLRATVLVDHVGTSGDPTMVPWAEAVATPAPPAFERVDFDAP
                     LWVLFSSGTTGAPKGIVHGHGGVLLEHLKLMGLHNDLRPGERFFWYTTTNWMMWNLVVS
                     GLLVDATVVLYDGSPVFPGPDRLWRLAEEHRVSVLGVSPGYLLACAKAGVEPSALDLGA
                     LRVVGSTGAPLPVSCYSWVSEHVGPSVQLVSTSGGTDVVSGFAGSAPTTPVWPGEISAP
                     MLGVALEAWDADGKPVVDEVGELVVTRPMPSMPVAFWDDPDGTRYREAYFATYPGVWRH
                     GDWMTVTGRGGVVISGRSDSTLN"
     CDS_motif       complement(17436..17489)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CLV43_RS07215_0001"
                     /evalue="1.50E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="CLV43_RS07215"
                     /protein_end="277"
                     /protein_start="259"
                     /score="17.7"
                     /tool="antismash"
                     /translation="VLFSSGTTGAPKGIVHGH"
     gene            complement(18263..19780)
                     /locus_tag="CLV43_RS07220"
                     /old_locus_tag="CLV43_102234"
     CDS             complement(18263..19780)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013222576.1"
                     /locus_tag="CLV43_RS07220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102234"
                     /product="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase"
                     /protein_id="WP_106186274.1"
                     /transl_table=11
                     /translation="MTDVECDVAVVGAGPVGLALASLLGRRGHRVVVLERRPRPYPLPR
                     AVHFDDETARVLAEAGVGEAVRAHGEPASVYEWRNADGRCLLRFDWSGTGPSGWPTATM
                     FHQPDLERALLAAAGAHESVTVLTGHTVTDLDAGEDGVILLVDAPDGPTRVRAAWVVGC
                     DGANSLVRDRMGTPVTDLGYFYDWLVVDVVPHVHRPWDPTNVQVCDPARPTTAVSGGPG
                     RRRWEFMRLPGESAAELGDEATAWRLLAPWDVTPETAVLERHAVYTFQARLADRWREGR
                     LLIAGDAAHLMPPFAGQGMCSGIRDAANLAWKLDLVLGGVVDPALLDTYQVERRAHVQH
                     AIAMSVELGKVICVADAEAAAQRDAFMLAHDADPARVLPPIPPSTLTGGVVGRDAAGAG
                     VLSPQPLLTLDGRTGPLDDLVGQAVVVAATVDPREVLSDDQAARLEALGAVLLYVADGV
                     LVPPGHVGVVIRPDHYAFGAAETRVALVEVVADLLARLPRPVALETR"
     gene            complement(19773..20696)
                     /locus_tag="CLV43_RS07225"
                     /old_locus_tag="CLV43_102235"
     CDS             complement(19773..20696)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020636663.1"
                     /locus_tag="CLV43_RS07225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV43_102235"
                     /product="VOC family protein"
                     /protein_id="WP_106186275.1"
                     /transl_table=11
                     /translation="MPLHRLTSITMGVPNVAETAAYYAEFGLQPTTGGTTFSTVDGGEQ
                     LRVADSARRRLLELGVGADDPDDLDRVATDLERLGFPVTRTAMSVSTLDPGTGTRVEVA
                     IASRLVQPEVPAPRYNGPGRHDRVGARADGVLRTDRVRPRKLGHVVLGSTDVETSQRLF
                     TEGLGFKVSDTVRGLAAFLRCSTDHHNVLVQQAPLQFLHHTSWQVDDVDEVGRGASSML
                     AADPGRHVWGLGRHHVGSNFFWYLRDPAGNFSEYYSDLDCIVDDALWKPGVWEGVHGLY
                     NWGPPPPPSFLAPEDLAALMTGAHSD"
     misc_feature    20720..20735
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.9"
                     /tool="antismash"
     misc_feature    complement(20987..21002)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.52"
                     /tool="antismash"
ORIGIN
        1 tgtcgacgat ggtgaagtag cgcagcagct cctccaccgc gggcagcgtc cgcgcggggt
       61 ccgccttgac cagtgccagc tggtcggggt tctccagcag ggcgaccgtg ctcagcgaga
      121 tcatgttcgc ggtggtctcg tggcccgcga gcagcagcag gaacgccatc gccaccagcg
      181 cccggtgccg gtaggtgccc tcctcgcggc ccttgatgat ctgcctgccg agcaggtcgt
      241 cctcgctggg gtccttctcc ttgagcagga tcaggtcgcc caggtaggtc tggacggcct
      301 ggaaggcggc gcgccggtcg gggacggacg actgcctgct gaccatggtc gcggtgtgcg
      361 cctggaagaa ctcgtggtcg ctgtagggga cgccgagcag ctcgcagatc accagcgacg
      421 gcaccggcag cgagagctcg cgcaccaggt cgacggggcg cggtccggcc agcatcgcgt
      481 cgatccgctc gtcgacgatc tcctggatgc gcgggcgcag cgcctccatc ctgcgcacgg
      541 tgaactcccc caggacagcg cgccgggcag gcccgtgctc gggcgcgtcc atggagatca
      601 gggacttctc ggcgtcgtcg tcctgcaccc tgcccatgac catctggggg aagtccgggt
      661 tcgagcggtc ggcgctgaaa cgggggtcgg acagcatcgt ccgcacgtcc tcgtgccggg
      721 tgagcgccca cgcccacttg ccgtcgagca ggttgaccct cgcgatcggc gcctcctcgc
      781 gcaggtcgcg gtactccttg ggcggggaga aggggcactc cctggtcagc gggaactgtt
      841 cgggacggat ctggaccgct tccgtcatcg tgatctcctc atcttgccgg tcaccgggtg
      901 gggcggcggg aacgtcctgg tcgtcggacg gagcggagcc ggttcggccg cgtccacccc
      961 gtccgaggac cgtgagtatg cggaggatta ccttccgctt ctctccaagg tagcgaagcg
     1021 gaagaaaacc gtccacctac ttcggggtgt agctcctcgt tttcccttac gcccggttgc
     1081 gcggcccccg tgcgacaatc ggcgcccgtt cgagtggaga ggcgcagccc gatggcagtg
     1141 gaccccgcca tgcccctgcg tgccgacgcc cggcggaacc gcgaccagat catcgcggcc
     1201 gcccggacga tcttcgtcga ccagggtccc gacgctccca tggaggacat cgcgcgcgcc
     1261 gcgggagtcg gcgtgggcac gctctaccgg cgtttccccg accgcgggac gctcatccgc
     1321 gaggtcgccg tcgacagctt cggccgggcg ctcaccgagg cacgggcctc catcgaggag
     1381 gagccgacct gctgggacgc cctggtccgg ttcatcgggt tctcgcagga gctccggctc
     1441 agcctgcacc tcgcgatgat ctcggcccag gcgggtgcgg tcatccgcga cgacccggcc
     1501 accgacgagt tccgccgggt cctgctgacc gacctcgacc acatggtcaa gggggcgcag
     1561 gcggagggca aggtcaggac cgacatcggc accggcgacg tggcgatgct gttcgtgctg
     1621 ctcatgcggc cgctgcccgc caagctggac gagatcgagg gcgcgagcga gcggtgcatg
     1681 accctcatgc tcgacggcct gcgcgcccac cccggcaccc cgctgcccag ccgccccatc
     1741 acctacgagg acctgctcga ctgacgggcg cggcacctcc cgcgcgcctg agcgtctgct
     1801 gaaagagccc cgcacgggta gcggacggac cgttccgcgc acgatgctca cgtcatggcc
     1861 gatctcgacg accgcgcact ggcgcgcagg ctgcacgacc ggttcgggtt cggaccgcgg
     1921 cccggtgacc tcgaccgcgg cgcggacgac gcgctggggc gcctgctcac cgcggcgccc
     1981 gccgccaccc ccgcgctcca gctcgctccc ccggccgcgc cgacgaagga caagcaggcc
     2041 aagcaggacg ccaacgcggc gcgcgcggcc gacgagaaga agctgctgtc gtggtggctc
     2101 ggccggatgg tcgccaccga caccgcccag gagcggctga cctggttctg gcacgggcac
     2161 ttcgcgacca gcgagcagaa ggtgcgcagc ccgttccaca tgctcgggca gaacgaggcg
     2221 ttccgacggc tcggcgcggg cgacttcggc gagctggcca aggcgctcgt ggtcgacccg
     2281 gcgctgatcc tgtggctgga cggcaacgac aaccgctcgg gtgcgccgaa cgagaacctg
     2341 gcgcgggagt tcatggagct gttcacgctc gggatcgggc actacagcga gaccgacgtg
     2401 cgcgaagccg cgcgggcgct caccgggtgg acggtgaagc gcgactccgc gcaggcggtg
     2461 ctgaccgcca agcgccacga cgacaagccg cagaccgtgc tcggggtgac gtcctcgttc
     2521 accgcggcgt ccttcgtgga caccgtgctg gcgaagccgg agtcggccgc gttcgtggtg
     2581 gggcgcctgt ggttccggct ggtgtcggcc accccgcccg caccggacgc ggtggaccgg
     2641 ctcgtcgccg cctacggcgc gaagcgggac gtcacggccg tgctgcgcgc gatcgcggcc
     2701 gaaccggcgt tccggtcggc cgacacgacg ctggtcaaac agcccgtgga gtgggtcgtg
     2761 gggctcatgc gcgcgctcga cgtgcgctgg gagtcccttg acgacaaggc cgtcaagcag
     2821 ctcgggaccg ggctgcgggg catgggccag gtgccgttgc ggccgcccag cgtcgggggc
     2881 tgggccgcgg gcggcgcgtg gctcacgacg gcggcgggcg tcgcgcggct gaccgtcgcg
     2941 cgactgctcg ccgcccgcac cgcgagcaag cccgccgacg cggaagccgc gcgcgtgctg
     3001 ctgtcggtgg acgcgtggtc cgaccggacc cgtgacgcac tggcgaaggt ggacaagccg
     3061 gaggacgtga tcgccgtggc cgcctgcgcc cccgagtacg tggtgagccg atgaccgcca
     3121 agctgaccag acgccacttc ctgaccctgt ccggcgtgac cgccgcgggc gcgctcgcct
     3181 acggcgccac ccgcgtcgac tgggacgacc tgctgtccgc ggcggccgac tcgccgctgg
     3241 cctccggtgc gggcgtgctg gtcgtcgtca cgctctacgg cggcaacgac ggcctcaaca
     3301 ccgtggtacc ggccgcggac agcgcttacc aagacgcccg acccgacctc gcctaccggc
     3361 cggaggaggt gctggacctc ggtgacggcc tcggcctcaa ccccggtctg aagggcctca
     3421 agggcctgtg ggacgagaag ggcctcgcgg tcgtgcgcgg ggtcggctac cccacccccg
     3481 accacagcca cttccgctcc atggcgatct ggcagaccgc ctccccgcgc acctccgtgc
     3541 ccaccggctg gctcggccgc tggctcgaca ccaccggcgc cgacccgttg cgcgccctct
     3601 ccgtcgaacc cgtgctgccg cccatgctcg ccggggcgaa gacggccgcc gcgtcgctgc
     3661 cgttgggagg gctgaagctg cccaccggca agctcggcga agccttccag gcgctcggga
     3721 cgccgtcagc cggtgaggag ccgtggcagg cgcgtgccgc caagtccatc accgacctgc
     3781 acagcgcggc caggatcctc ggcggcgccg tccacgacgc ggcggaggac gaccccgacg
     3841 agaagcgcga caagggcgcc tcggccggcg gcgcgtccgc cctcggcgcg caactggacg
     3901 ccgtcgccgc gctcatcgag gccgaggtgc ccacccgcgc ctactcggtg tccctgggcg
     3961 gcttcgacac ccacgccgac gaacgcgaca cccagcaacg cctgctcacc gagctcgaca
     4021 ccgcgttgac cgcgttcgcc aaacgcctca agggcaccga ccgcggccgc caggcggtcg
     4081 tcctcgtcta ctccgagttc ggccgccgcg tccacgcgaa cgccagcgac ggcaccgacc
     4141 acggcaccgc gggcccggtc ttcctgctcg gcgcaccggt caagggcggc ttcttcggcg
     4201 accagccgag cctcaccgac ctggacaacg gcgacctcaa gcagaccacc gacttccgcg
     4261 acatctacgc caccgtgctc caggacgtgc tcgacaccga tccggggaag gtcatcgagg
     4321 accacagggg gcggatcgac gggctgttgc tgtgaggcgc aattccccgg caatgacatg
     4381 accgcggcaa ttcgtgaacg acactcgact ttccgtggtc gaaaccggag aaatacggcg
     4441 gccgcatgtc atatgacgct cccgacgtcc gttgcggacg ttcgcggtgc ggaattgacg
     4501 actcatgacg agcgatcccg gagaacagca tccgcggaac gagcggatga ggaagaaccg
     4561 gcgtggacag cccgagtcgt ggtcgccgcg aacagccgac gcggataccg cgcaagattc
     4621 ctgctggcaa ccggttcgtg ccggtgagcg acccggcccg cgcgacgatg accatctccg
     4681 tcggcaacca ggtccagctc aacggcccgc actcgaccac ggtcgagcaa cccaccctct
     4741 cggcgtaccg ggacgcgctg ggaggtctcc tgaaaccccg cgtcaccgcg cgaccaaggt
     4801 cgacgtgatc ttgggaccgc gtggacgtca ccgaggcggg caccgtcggc ctgccctcgg
     4861 tctggacgcg tccgtgtcct acggtcgcac ggccttcatc gtctacgagt cggagtactc
     4921 cagccaggag gtcgaggccg cgttgcgggt ctcggcgacg gcgcggttgg gtccgatccc
     4981 ggtgggcgcg ggtgtcgagc cgaagtggtg gagcgccgac acgctgggca agagcagctt
     5041 caccgggtac gtcctgggcg gctcgggtcc tgacgcggtc cgcgcctcgc gggggctgga
     5101 cgacgtgcag gcctacatca caggtggcgg gaactactcg gccgagtccc caggggcgcc
     5161 gatcgcctac agcctctcga acctcggcga caacgccatg gcgggcgccg ggcggacggt
     5221 cgactacccg gtccgcaggt gcgagcggat ccgcggtcgc gtcgccgtga agctcaagca
     5281 ggtcaaggtc gactcggagg acgacgtcga cctgtgcggc tcgatctccg cgtggcacgg
     5341 caccacgcgg gtctcgttgt tcgaccggga ctgcaaggac ggccacaagg tcacggtcga
     5401 gcacgagcac ccgtgggagc cgggtgtcca ggagccgctg gaggtcacca cccgcgacgg
     5461 ccagtcgatc gacctgcacg tccgcctggt cgagtccaac acgctgttcc ccgaccagga
     5521 gatcgagtac cgcgtcgtga acaagcggta cgaggacggc tggcgggacg tggcggaggt
     5581 caagctctcg cgggaggaca cctcggtgac cgtggtggtc gagctcatcc cgacctagcc
     5641 acccgtccga ccgaccagcc cccgctcaca acccctcccc cgccgccgcc aaccgctccc
     5701 tcatccactg gtgcgcgggc acgagcatgt tgcgggggtg ccagaacatg ccgatcgtca
     5761 tccgcggccg ctccacggcc agtgggacct cccgcagccc caacgcgggc ccgaggtggt
     5821 cgaacaggcg gcggggtgtg agggtgacga ggtcggagcc cgcgaccgct tgcagggcca
     5881 gcgtgaacga ctcgacggtg acggggctgg gtgtggtcac gccgagttcg gcgagcttga
     5941 cggccgagac gacgcgttgg cccgcgatgc cgttgacctg gacggcgcgg gtggtggtca
     6001 gggcttcggc ggtgaggggt tcgggcagcc cgtggttgtc ccggtcggcc gcggcgacga
     6061 actcgtcggt gaacacgggg acgtggggga agttgagcag ttccggtgtc tggagctgca
     6121 agggccagaa caggacgtcg caccagccgg tccggagcag ctcgacgagg tccgcgcgca
     6181 gggaggcgac ggtgacgcgc acgcccggcg cgtcggtggc gaggccgcgc agggcgggca
     6241 ggacgaggac gcccgcgacg tagtcgctgg ccatgagggt gaacgtgcgg cggtcggtgg
     6301 cgggggtgaa ggaccggccg gagctgagca cttcgcgggc ggcgaccaat gccgtctgga
     6361 ccgggcctac cagcgactcc gcgaacgggg tgaggaccat cgcgcggccc tcgcggacga
     6421 gcagcgggtc gtcgaagtgg cggcggagct tggccagcgc ggcgctcatc gcgggctggc
     6481 ccatcacgag ccggtcggcc gccttcgtca cgttgcgctc cagcaggagc gcgttcagcg
     6541 gaatcagcag gttcaggtcg agcctgcccc agtccgtggc caccgccggg atcctcctcc
     6601 ccgccgtccc gactggcaac aacgcgcccg ttgagacggc accgcgatca tccgcgcagc
     6661 tcccgcgacc tatcgaaccg gtcgatggag cccatcccga aatggtcggt gccgagcccg
     6721 tcgaccccgt cctacgctgg caggacgccc accgaatcca cagtggactt gtcacgcgcg
     6781 ccgtttcccg gcaccggagg gacctcacga tgaccgacac cagcgacctc ccgtcccacg
     6841 cccgccagcc cgccatcgcg agcggccgcg ccgccgtcgg cgtcgccctc gccgcgatcg
     6901 cctccgtcgc gctgaacacc gtgatcgccg tgctcgcgaa cgccgcgctg cccgccgagg
     6961 gcgtgcggaa ggggctgacg ctgaaggagt acgcgccgct gaccgtcgtg gggatcctgc
     7021 tcggcaccct ggcgtggtac ctcgtccggc gcagcgcccg cgacccccgc gccgtcctgc
     7081 gggtgctcgt gcccgcggcc gtcctcgtgt ccctcgtccc cgacttcggc atcctcgcgg
     7141 ccggagtgca cctgctcaac tccctggcgc tcgtcacgat gcacctcgtc gtggccgcca
     7201 tcaccgtgcc cgtcctcgtg aaggtgctgc cgctgccgca ctcacgttcc tagccccttc
     7261 cggacgacgg gtccgcgact ccgcgcggcg cattggcgcc gcgcggtttc gcgcgttcca
     7321 cgaacgtggg cgcggcgcgc accgaaagcg gtaccgacgc gatcgaagcg gtaccgaagc
     7381 gatcaccgcg ggttccggca tccaccgagc ggtgacgaac actgggccgt tcaggtattc
     7441 gcaccgccgc aattcctcgg acgccaattc cgcttcggtg ccgcattcga gggacgacgg
     7501 caatgccccg aaagtgtcat tgcactcccg aaccgccttg ctatgttcga acagcacaac
     7561 ggcaccggga attcgacctc cgcgattccc ggtttttccc cgcacgtcta ccgattggtg
     7621 gctcccgctg tgaccgcgac cgaatcggac accacctccc ccggtgccgc gtcactgctg
     7681 tcgagcctga gccgggccgc cgcgcgcaac ctggccacca cgacgaagtc cgtcccgcag
     7741 atgcagggga tctcctcgcg gtggctgctg aagctgttgg agtggaagca ggtcgacggc
     7801 ggcacctacc gggtcaaccg gcggctgagc cacgccgtcg gcgacgggcg ggtgacgttc
     7861 gagcagacgg gttccgcggt gcgggtcgtc ccggcggagc tggccgagct cgcgccgctg
     7921 cggggctacg ccgacaccgc ggtgctggcc gagctggcgc ggcgcttcgc gcgggtcgag
     7981 ttcgcgccgg gcgacgtgct cgccgggttc ggccaccggg ccgaccgggt cgtgctcgtc
     8041 gcgcacggca agatcgccaa gtccggtccc ggcgcgtacg gcgacgagac gtcgttggga
     8101 gtgctcaagg acggcgacca cttcggcgcg caggcgctgc tgtccgccga cgggatctcg
     8161 gagttcaccg cgaaggcgat cacggccggg acggcgttga cgttgtcgcg cgacgacttc
     8221 gaggccgtgc tgcgccggtc cgggtcgttg cgcgcccagc tggaccgcgc gtccgaggtg
     8281 cgcgccgcgg cgaacgagca cggcgagtcc gagatcgaca tcgcgtccgg gcacggcggg
     8341 gaaccgccgc tgcccaccac cttcgtcgac tacgagggct cgccgcgcga gtacgggctc
     8401 agcgtggcgc agaccgtgct gcgggtgcac acccgcgtgg ccgacctcta caaccagccg
     8461 atggaccagg tcgagcagca gctgcggctg accatcgagg ccctgcgcga gcgccaggag
     8521 cacgagctgg tcaacaaccc ggacttcggc ctgctgcaca acgccgactt cgcccagcgc
     8581 gtcgccaccc gcaccggccc gccgaccccg gccgacttcg acgagctgct gtcgttggtg
     8641 agcaaggaac ccggcttctt cctggcgcac ccgcgcacga tcgccgcgtt cttccgcgag
     8701 tgcaccaaag cgggcgtcta ccccagcgac cccggccccg acggcggcga ccggatctcg
     8761 tggcggggcg tgccgatcta cccgtgcggc aagatccccg tcagcgcggg ccgcacgagc
     8821 tccgtgctcc tgatgcgcac cggcgaggac aaccgcggtg tgctcgggct gcgccaggtc
     8881 ggactgcccg acgagtacga gccggggctg agcgtccgcc gcatgggcgt ctccgaccgc
     8941 gcgatcacct cctacctggt cagcacctac tactccgccg ccgtgctggt gcccgacgcg
     9001 ctggccgtgc tcgaaggcgc ggaggtcagc cgcgagggct agcccaccag gcggtcctcg
     9061 cccgttctcc cgcaccccta ggaaaggaac ccctcctgtg accgcagtca gcaccgctcc
     9121 cgccgacgtc ctccgcaccg cgtaccagaa gtccgtagcg tcgtactgga acgccgagca
     9181 ggacccggtc aacctgcggc tgggcgacgt cgacgggctc taccaccacc actacgggat
     9241 cggcgaggtc gacctgtcgg tgctggaggg gccgcaggac acccgcgacg cccagatcat
     9301 cgccgagatg caccggctgg agacggcgca ggcggacgtg ttgctcgacc acctcggcga
     9361 catccgtccg caggacaggc tcctggacgc cgggtgcggg cgcggcggca cgagcatcat
     9421 ggcccacgag cggttcggct gcgaggtcga cggcgtgtcc atctcgcaga agcaggtgga
     9481 cttcgccaac cgccaggccg cggtgcgggg cgcggagggc aaggtccgct accacttccg
     9541 caacatgctc gacaccgggt tcgagagcgg gtcgcggcgg gccatctgga acaacgagag
     9601 cacgatgtac gtcgatctgt tcgagctgtt cgccgaacac gcgcgccagc tcgagttcgg
     9661 cggccggtac gtgacgatca ccgggtgcta caacgacgtc accggcggcc ggtccaaggc
     9721 ggtggcccag atcgaccagc actacacgtg caacatccac ccgcgcagcg cgtacttcaa
     9781 ggccatgacg gccaacggcc tggtgcccat ctcggtcgtc gacctgaccg cgcagacgat
     9841 cccgtactgg gagcttcggg ccaagtcgtc ggtggcgacc ggcatcgagg acccgttcct
     9901 caccgcgtac cgcgagggca gcttccacta cctgctcatc gccgccgacc gcatctgacc
     9961 cgagccgccg cggccgagta cccccggaga aagcgaagcg atgccggacc tgcagcacac
    10021 cacgtccacc ttcaccggtc tggggacctc ggccgcgcgg ttcgcggccc ggctgggcag
    10081 cggccgcgag caggggtctc cggaccccga gaacgggaac gaccccgcgt acgcgcaccg
    10141 gccgtggggc gacgggtcgg cgtcgccgct gtactgcccg ctccccgagc ggatcgacga
    10201 caccctggcg caggaggtcg accggcggct ggcgctctgg gcgcgggact gcgggttctc
    10261 cgccgaggag gccgaacagc tgggccaggc ggagttcgga cggctcgtcg tgctcgcgca
    10321 cccggactgc gacgacccgg accggctgct catctcggcc aggctcaacg ccgcgtggtg
    10381 ggccgcggac gacctctacg cggacgacac cgcactgggg gccgtgccgg ccgagctccc
    10441 gcaacgactg gctctggcga tggccgccat ggacccgctg cccaccgcgg gctcgttctc
    10501 cgacgagctc gacgaggcgc tgggcgggga caaggtgctc gtcgcgctgc gctcgggcat
    10561 ggagcacctg gcgggctacg ggaccccggc ccagttccaa cgggtctgct actcgacgtt
    10621 cgcgatgttc gtgagctgga cggcctacgg ggcgtggaag cacaacgacc gcaccccgcc
    10681 cgcgtgggag tacctcgcgg ccaggcagca cgacagcttc tacacgtcga tgacgctcat
    10741 cgacgtgctc ggcgggtacg agctggactc gaacctgttc tacgaaccgg aggtgcgcgg
    10801 cgcggcgatc ctcgcgggca cggcctcggt gttggtgaac gacctgttct cggtgaccaa
    10861 ggacctggcc gacgagaacc cgccgtgcaa catggtgctg caggtcgcgg cggaccggga
    10921 gtgctcggtg ccggaggcgg tcgaggccgt cgtcgagctc cacaacggac tcgtgcgcga
    10981 cttccaggac gtgtaccgga aaacgcggtt cgtgccgtcg ccgcagctgc ggcggttcat
    11041 gcgcggactg cgcgcgtgga tgggcggcgg cttcgagtgg cactccacca gcccgcgcta
    11101 ccggaccccg tcctgacccg acaacaccga accgaacacc tgtgtcggtg tggccgagat
    11161 ccggccacac cgacacggaa gcgtcaggcg ctttccgccg cggcggcgcg tccggtctgc
    11221 ctgccggtga acaggcagcc gccgaggaag gtcccttcca gcgcgcggta gccgtgcacg
    11281 ccaccaccgc cgaagcccgc gacctcgccc gcggcgtaga gaccggggat cggttggccg
    11341 gtggagccga ggacgcggcc ggacaggtcg gtctgcaggc cgccgagggt cttgcgggtg
    11401 aggatgttca tccggatggc gacgagcgga ccggccgacg agtccaggat cttgtgcagc
    11461 ggggccgtgc gggcgagctg gtcgccgctg taggccaggg agttgcggat gcccatgatc
    11521 tgggtgtcct tggtgaaggg gttgtcgacc tgctggtcgc gcaaggtgat ctgcctgcgc
    11581 agggcgtcga ggtcgacgag gttgccgccc gcgatccggt tcatgcccgc gacgaggtct
    11641 gccagcgagt tggcgacgac gaagtcctct cccctgtcca tgaacgcctt caccggcggc
    11701 ggggtgctgt tgagcaggcg gctcgccagg tagccgagga ggtccttcct ggtgagctcg
    11761 gggttctgct cagagccgga gagcacgaac tccttgtcga tgatcttctt gttcagcacg
    11821 aaccacgagt acccgtggcc cgagcgctgg atcagctcca acgtgccgag cgtgtcgtag
    11881 ctggggacac cggggttggc caggcggcgg ccctcggcgt cgaaccacat cgacgacggc
    11941 gcggcgagca cgcggatccc gtggccggac cagatggggg tgtggttggt cagcccctcg
    12001 gtgtagtgcc acatccggtc gcggttgacc agtcgcgctc ccgccagctc gctgatcgcc
    12061 agcatccggc cgtcgacgtg cgcgggcaca ccggtgacca tgcgcgcggg cggggtgccc
    12121 aggcgggcgg gccagttgcg gcggacgagg tcctggttgc cgccgatgcc gcccgaggtg
    12181 acgacgacca tcggggcgta cagctcgaag tcgccgacct tggtgcggga gctgggtgtg
    12241 ccacgggcgg cgctgctggg ctgcagcacg ctgccgcgca cccccgtcac ggcgccgttg
    12301 gtggtgatga gcccgtccac ctggtggcgg aagcggaagg tcaccgttcc ccgtgccgcc
    12361 gcggcgcgca cgagcttctc gaacggctcc acgacaccgg gtccggtgcc cagcgtcagg
    12421 tggaagcggg gcacggagtt gcccggcccg tcggcgtgct gcccgcctcg ttcggcccag
    12481 ccgacgatcg gcacccagct cacgccgagg cccgacagcc acgaccgctt ctcccccgcg
    12541 gcgaactcca ggtacttctc ggcccacttg gccgcccagt agtcctcgcc cagcggggtg
    12601 tcgacgccgc ggtcgaagcc cgcggtgttg aaccagtcgc cgcgggccag gtcgagcgag
    12661 tccttgatgc ccgccagccg ctgttcggcg gagtcgacga agaacagccc gcccaacgac
    12721 cagaaggcct gaccgcccag gctcgcctcg ggttcctggt ccagcagcag gaccttgcgg
    12781 cccgcggcgg ccagctccga ggtcgcgacg agcccggcca gccccgatcc gacgacgatc
    12841 acgtcggcgt cgaccctggg tgccgcggac gcctgcccga gtcccagggt gcccatggtc
    12901 gtggacgcgg cgagggcgcc tccggccgcg aggaggtgtc gtcggctgat gttcctgctg
    12961 ccaggtgaac tcatcgttga gcccttcagg ggaacgggtg gaacggcttg tcggcggcgg
    13021 cggcttcctg gttactgtcg ggtcaaccca cgtaaccagg gtgggatggg cggcggatag
    13081 ggtcgcgtca ccaaacgccg tcgatctcgt tgtgcaccag ccacaacgat gcgtcggagg
    13141 tgctgtgcgg gaccaccgga tgaccgcggt cgcgctgcgg gtgatggccg cgatggccgc
    13201 cgacgaccaa gtcgtgacca gggtggtcgg ggccgcacgc gagaactccc ccgaggtcgc
    13261 ccgcctgccg gaggcggaga accgcaggca catcgccacc ctgctcaccg ccggggccgc
    13321 ccacctgcgg ggcggcgacg gcgacttctc cgccgccgag gcgctgggcg ccgaccgcgc
    13381 ggcgcagggc gtctcgatcg ccggtctgct gcgcggggtg cacgcgggcc gcgcggaggt
    13441 gatccgcgcc ggggtggagt tcgcccgcgc gacgggggtg gacgactcca cgatcctcga
    13501 cttcatcgtg gacgtggact cctacgtcgc cgcggtcgag cggcacatca tcagcagcta
    13561 ccacaccgcc gagcttcaac tgtcccgcac ggcccgcgac ctcaacaccc aggtgctgcg
    13621 cggactcctg gtgccggacg gcgctttccc cgacgcggcc gagctgggcc gggtggggct
    13681 gcgaccggaa agccgctacc actgcgtggt ctccgacgtc accgatccga gccgcgccag
    13741 gtcgctcgag cagcggtggc agcgctccgg cggcgtgtac ggactggtcg aggggcggct
    13801 cacgggtgtc ggcccgcacc cgccgtgcgg tccggacgac gacgcgccgc tgctcgtcac
    13861 gtcccccgcc gcgccgttga cgtcgctgcg cgggatgtac cccctgtgcg tgcaggccct
    13921 ggccgtcgcc tcggcccgcc gggcccgcgg cacccacccg ctcaccgacc tggcggccga
    13981 gacggcgctg gccgcccacc ccgccctggc tgccaccctg accgacgacc tcctgcggcc
    14041 gctcgacccg aagagcggct tccaccacga gctcgtcacg accgcgttgt gctacctcga
    14101 ccacggccgc cggatcggta ccgcggccgc cgtgctgcac atccacccca acaccgtgcg
    14161 ctaccgcctc gaccggttgg cggagctcac cgacgtcgac ctcaacggcg tcgcgcaccc
    14221 ccaccgctcc cacgtgctca ccacggtgca cacgtggtgg gcgctgcgca cctggctcga
    14281 ccgcggcgcg aaggggaggt gaacctcagg cgtcggcccg ccagttctcc cgcgcccacg
    14341 tctcgaaacc ggtgagcggg atgcccagct ccctgccgta ctcgggcctc gcgggctgtc
    14401 cggtggtgtt caaccgctcg tgcgacgcgc ccatcggggg catcccggcg gcgagcgcct
    14461 gctcctcggt catgtcgggc gccgccagcg gcgtgcccag cacgcgggag aggacctcgg
    14521 cgatctccgc catcgacagg tggtcgctgg cgaactccag ctcgacgccg tcgaaccgca
    14581 cggggtcggc gatggccgcg gccgccgccc tgccgatgtc ctcgaccgcg gccagcgaca
    14641 gccgggtgcc cggcttcagc acgctgacca gccctccctc gaccccgcgc gggaacagga
    14701 aacccatgga gggcaggaag ttctccatga agaagcccgg cttcaggatc gtccagtgct
    14761 cgaacccggc ctcgcggacc cggtcctgga ccgcggcctt ggcgtccatc gaccgcgtca
    14821 tcgaggacca gcgactctcc gtccactgag gaccttcgcg gtgccggccc gcaccggtca
    14881 ccgaggtgtg cacgaactgc ggcacaccgg cggccttcgc gccctcgacg aggttggtgc
    14941 cctgggcgac ctcgccgtcg aagtcgaagc cctccccggt gaaggggggc atctgcacgg
    15001 agaagaccgc gcgggcgccc ttggccgcca gcgccacgga gtcgcggtcg cccaggtcgc
    15061 ccacgaccag ctcggcgccc agcgcccgga ccgcctcggc ccggtcggag gccgggtcgc
    15121 gcacgagggc ccggacgggg atccccgccg cgatcagggc gcgggccgtg gcaccgccct
    15181 gcctgccggt ggcaccggtg accaggacgg gcgcggaatc ggtggacatg ctgctcctcg
    15241 gggggttcgg caacaaacgg cggggtccgc cgcttgttgc cgaacaatac ggcggccccc
    15301 gccacttagc aagccgcccc ggatcagctc accatggacc cgtgggtgaa cgcgcccgcc
    15361 gtcacggcct ccgcgacgca cacctcgaca ccccgaggct ccaccccgag aacctgccgg
    15421 atgtcgtccg tcacgaacgc cgacgcaccg ccgcggaaca gctcgtacat ctcgccgacg
    15481 tgccggacct cccactccgg cagaccgcgc cccaccaacg agtcccggac cgcgtcgagg
    15541 ccgacgtcca cgacggtcac cggcgtgccg gtcccggccg ataccaggtc ggccagctcc
    15601 tggtaggtga cggcccgagg accggtcagc accagcgtcc tcccgtccca cgcgtcgctc
    15661 gtgagcgccc gcgcggccac cgcgccgacg tcccgcgcgt ccaccaggct gatcgccgcg
    15721 gtgccgagcg ggttcggcag cacaccggtg gtgcgcaacg cgcccgcgac cgcctggttc
    15781 acgatcacct ggccgaaccc gttggggcgc agcacgacga acggctgtcc cccggcgcgc
    15841 aggacctgct cgacctccca gtgctgccgt ccgacgagcg gtccgtccgg cacgaccgac
    15901 gtgctcgtcg cggacagctt cacgacgcgc agcggcgcgc cccgcagggt ccgcaggacc
    15961 ctctgctgcg tgtcggccat gtccagtccg tgcggggaga gcaggagaag cgactccacc
    16021 ccttcggcgg cggcgagcag gcccttctcg tcgagcgggt cccacccgac gacctcgacc
    16081 gcgtccggca gcaccgaccg cgcgcggtcg gcgtcgcggg ccagcacccg gacctccgtc
    16141 ccgccctcca gcaacgacga cacgacgtgg ggcccgatgt tcccggtggc gcccaaaagc
    16201 agtgcggaca tgggtgttcc cttgctcctt cgtggatggc gggaccgcgt cggtcccgtg
    16261 gtcacgggcc tcggcatcgg ggcccgcgcg gtggtcgtgc tccgggcggg tcaggactcc
    16321 gcggcgccgg acgccgggtt ccgggcgagc cgggcgtaga agtcgagcag cgcggggtcg
    16381 tccacggcgc cgcggtcgag cgcccgctcg accggcacgc cctgaagcag gcgcttgacc
    16441 ggcacttcga gcttcttgcc ggtgcgggtg tgcgggatgc ccggcaccgc gatcacgtcg
    16501 tcgggcacgt gccgcggcga cgcctcggcg cggatggcgg cggtgatccg gtcccgcaac
    16561 ggcccgtcga gcacgacgcc gtcctccagc acgacgaaca gcggcatcca gtacccgccg
    16621 tcggccagct ccgctccgat caccagcgcc tcgcggatgc cgggcagctt ctccaccacg
    16681 gcgtacacgt ccgcgctgcc gagccggacg ccgtgccggt tgagcgtgga gtccgaccgc
    16741 ccgctgatga cgacgccacc gcgcccggtc acggtcatcc agtcgccgtg ccgccacacg
    16801 ccggggtagg tcgcgaagta cgcctcccgg taccgggtgc cgtccgggtc gtcccagaac
    16861 gccaccggca tcgacggcat cggcctggtg acgacgagct cgcccacctc gtccaccacc
    16921 ggcttcccgt cggcgtccca ggcctccagc gcgacgccca gcatcggcgc ggagatctcc
    16981 cccggccaca ccggtgtggt cggggcactg ccggcgaagc cgctgaccac gtcggtgcca
    17041 ccgctggtgg agacgagctg caccgacggg ccgacgtgct cggagaccca ggagtagcag
    17101 gacacgggca gcggcgcgcc ggtgctcccc accacccgca gcgcgccgag gtcgagcgcc
    17161 gacggttcga cgccggcctt ggcgcacgcc agcaggtagc cggggctcac gccgagcacc
    17221 gagacgcggt gctcctccgc gagccgccag agccggtccg ggccggggaa caccgggctg
    17281 ccgtcgtaga ggacgacggt ggcgtcgacc agcagcccgg agacgacgag gttccacatc
    17341 atccagttcg tcgtcgtgta ccagaagaac cgctcgccgg ggcggaggtc gttgtgcagc
    17401 cccatgagct tgaggtgctc cagcaggacg ccgccgtggc cgtgcacgat ccccttcggc
    17461 gccccggtgg tgccggagga gaacagcacc cacagcggcg cgtcgaagtc cacccgctcg
    17521 aacgccggcg gcgccggggt ggcgacggcc tccgcccagg gcaccatcgt cgggtcgccg
    17581 gacgtgccca cgtggtcgac cagcaccgtc gcccgaaggg tcggcagcag gtcgcgcagc
    17641 cgggccgcgg cggcccgccg gtcgtggacg cggccgttga accggtaccc gtcggccgcc
    17701 acgagcacgg tcggtgcgag ctggccgaac cgcgccgcgg caccgtccgc gccgtagtcc
    17761 tgcccgcaca ccgaccagac cgcgccgagg ctcgcggtgg cgaggaacgc gaccacggcc
    17821 ggtgccgcgt tgggcaggta gccgaccacc cggtcgccgg gaccgacgcc ctgcccgcgc
    17881 agccatccgg cgaacgcggc caccctggag cgcagctccg gccagtccac cgacgtggtc
    17941 gtgccgtcct cggtgaccgc gatcagggcg ggcccgtcgc cgccgccgcg caggacgtgc
    18001 tcggcgtagt tgagccgggc gccggggaac cagcgggcgc cgggcatcgg ctcgtcgtcc
    18061 agcacccggt cgaacccgtt gtccgaccgg acgtcgaagt actcccagac ctcgccccag
    18121 aagccttcga ggtcctcgac cgaccacttc cacagctcgc ggtagtccgc catcgaccgg
    18181 ccggtcacgg cctccgcccg gcaggtgaac cggatgatcg acgcgtcggg gtcggggtcc
    18241 ggccgccaga ccggtcccgc gctcaccggg tctccagcgc gaccggccgc ggcagccggg
    18301 cgagcaggtc ggcgacgact tccacgaggg cgacccgcgt ctccgccgcg ccgaacgcgt
    18361 agtggtcggg ccggatgacg acgccgacgt gaccgggcgg caccagcacc ccgtcggcca
    18421 cgtacagcag caccgcgccg agcgcttcca gccgagccgc ctggtcgtcg gacagcacct
    18481 cccgcgggtc gaccgtggcg gcgaccacga cggcctgccc gaccaggtcg tcgagcggcc
    18541 cggtgcgccc gtcgagcgtc agcagcggct gggggctcag cacgcccgcg cccgccgcgt
    18601 cccggcccac gacaccaccg gtcagcgtgg agggcgggat cggcggcagg acccgcgccg
    18661 ggtcggcgtc gtgggccagc atgaaggcgt cgcgctgcgc cgccgcctcg gcgtctgcca
    18721 cgcagatgac cttccccagc tccaccgaca tggcgatcgc gtgctggacg tgggcccgcc
    18781 gctcgacctg gtaggtgtcc agcagggcgg ggtcgaccac cccgccgagc acgaggtcga
    18841 gcttccacgc caggttggcg gcgtcgcgga tgcccgagca catgccctgc cccgcgaacg
    18901 gcggcatgag gtgggcggcg tcccccgcga tcagcagcct gccctcccgc caccggtcgg
    18961 ccagccgggc ctggaacgtg tagacggcgt gccgctccag gacggccgtc tccggcgtga
    19021 cgtcccaggg tgcgagcagc cgccacgcgg tggcctcgtc gcccagttcg gcggcggact
    19081 cgccgggcag ccgcatgaac tcccagcggc gcctgccggg gccgccggag accgcggtgg
    19141 tcggtcgcgc cgggtcgcag acctggacgt tcgtcgggtc ccacgggcgg tgcacgtgcg
    19201 ggaccacgtc gacgaccagc cagtcgtaga agtagccgag gtcggtgacc ggggtgccca
    19261 tgcggtcgcg gaccaggctg ttggcgccgt cgcacccgac cacccaggcg gcccgcacgc
    19321 gggtcggccc gtccggtgcg tcgacgagca ggatgacccc gtcctcgccc gcgtcgaggt
    19381 cggtcacggt gtggccggtc agcacggtca ccgactcgtg ggctccggcc gcggcgagca
    19441 acgcccgttc caggtcgggc tggtggaaca tcgtggcggt cggccagccc gacggcccgg
    19501 tgccggacca gtcgaacctg agcaggcacc gcccgtcggc gttgcgccac tcgtacacgg
    19561 aggcgggctc gccgtgggcg cggacggcct cgccgacgcc cgcctcggcc aggacccgcg
    19621 cggtctcgtc gtcgaagtgc accgcgcgcg gcagcgggta cggccggggc ctgcgctcca
    19681 gcacgacgac ccggtggccg cggcggccca gcagggacgc cagcgcgagg cccaccgggc
    19741 ccgcgccgac gaccgccacg tcgcactcga cgtcagtcac tgtgggcgcc ggtcatcagc
    19801 gcggcgaggt cctcgggagc caggaacgac ggcggcggag gcgggcccca gttgtagagg
    19861 ccgtgcacgc cctcccagac gcccggcttc cagagcgcgt cgtcgacgat gcagtcgagg
    19921 tccgagtagt actcggagaa gttgcccgcc gggtcgcgca ggtaccagaa gaagttggac
    19981 ccgacgtggt ggcggcccag cccccagacg tggcggccgg ggtcggcggc gagcatcgag
    20041 ctggcgccgc ggccgacctc gtcgacgtcg tcgacctgcc acgaggtgtg gtgcaggaac
    20101 tgcaaaggag cctgctgcac caggacgttg tggtggtcgg tcgagcagcg caggaacgcc
    20161 gcgagcccgc gcaccgtgtc gctgaccttg aagccgaggc cctcggtgaa caggcgctgg
    20221 ctggtctcga cgtcggtgga gccgagcacg acgtggccga gcttgcgcgg ccggacccgg
    20281 tcggtgcgca gcacgccgtc ggcgcgggca ccgacccggt cgtggcggcc cggaccgttg
    20341 taccgcggcg ccgggacctc gggctggacc agccgggagg cgatggccac ctcgaccctg
    20401 gtgccggtgc ccggatccag ggtcgagacc gacatggcgg tgcgggtgac cgggaaaccg
    20461 aggcgttcga ggtcggtcgc gacccggtcg aggtcgtccg ggtcgtcggc accgaccccg
    20521 agctccagca ggcgccgccg ggccgagtcc gccacgcgca gctgctcgcc accgtccacg
    20581 gtggagaagg tggtgccccc ggtcgtgggc tggaggccga actcggcgta gtacgcggcg
    20641 gtctcggcca cgttcgggac gcccatggtg atggaggtca ggcggtgcag gggcatgtca
    20701 catctccttc gacgcggcga cgaactgctg gtcgagctca ccgatgccgg cgatcgtgct
    20761 gacgagccgg tcccccggct tgaggaacca gcgggggtcc cgtgccgcgc cgacgccggc
    20821 gggagtcccg gtgaagatca cgtcaccggg ctccagcggc agcacggcgg acagcctggc
    20881 gatcagctcg ggcacggaga acacgaggtc ggcggtgttg cccttctgga cggactcgcc
    20941 gttgaccgag caccccaggt ccagggcgtc ccggtccagg cccgccacga ccagctcgtc
    21001 cagggtgacc agccaggggc ccatcggcgt gaaaccgggg aaggacttgc cgaggctgaa
    21061 ctgcggggcc gggccggcga gctgcgtcgt ccgctcggac aggtcctgcc cggcgg
//
