MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AMK48234.1 salicylate-AMP_ligase BGC0001351.3 NRPS:Type I 35.0 97.8 286.0 2.35e-89
AGK13425.1 enterobactin_synthetase_component_E_(2,3-dihydroxybenzoate-AMP_ligase) BGC0002528.3 NRPS:Type I 34.0 97.5 266.0 1.18e-81
QQZ01621.1 long-chain_fatty_acid--CoA_ligase BGC0002497.3 other:other 35.0 95.1 259.0 2.15e-79
AEF33098.1 3-hydroxypicolinic_acid:AMP_ligase BGC0001039.5 NRPS:Type I+PKS 34.0 96.2 259.0 3.26e-79
ABS75234.1 DhbE BGC0001185.5 NRPS:Type I 32.0 97.3 258.0 6.1e-79
ABW70812.1 PchD BGC0002475.3 NRPS:Type I 32.0 97.3 254.0 3.5e-77
ABY66018.1 CoA_ligase BGC0001008.5 PKS:Iterative type I 33.0 97.1 253.0 1.14e-76
MBE3202941.1 AMP-binding_protein BGC0002410.3 NRPS:Type I 31.0 101.6 250.0 2.91e-75
AAZ55904.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000359.5 NRPS:Type I 33.0 97.8 248.0 4.08e-75
AGY30675.1 Ann3 BGC0001298.4 PKS:Type I 35.0 94.8 246.0 1.06e-74
ADZ13540.1 YtkG BGC0000466.5 NRPS:Type I 34.0 95.0 247.0 1.57e-74
AIL50189.1 putative_5-aminolevulinate_CoA-ligase BGC0000213.4 PKS:Type II 35.0 96.4 246.0 2.07e-74
NPC94428.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002695.2 NRPS:Type I 30.0 96.9 244.0 1.57e-73
QIE08740.1 salicylate-AMP_ligase BGC0002544.3 NRPS:Type I 34.0 96.2 242.0 6.63e-73
ADC79613.1 BafX BGC0000028.5 PKS:Type I 33.0 96.0 242.0 8.63e-73
AGE11892.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000366.5 NRPS:Type I 32.0 96.6 240.0 1.02e-71
AGM05529.1 long-chain_acyl-CoA_synthetase BGC0002098.2 PKS 33.0 95.9 238.0 1.18e-71
ABS74201.1 YngI BGC0001095.5 NRPS:Type I 31.0 100.4 238.0 3.77e-71
BBA21084.1 putative_5-aminolevulinate_CoA-ligase BGC0001740.5 NRPS:Type I+PKS 33.0 94.8 234.0 3.22e-70
EFL06871.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000300.5 NRPS:Type I 34.0 95.3 233.0 1.02e-69
CAI94705.1 putative_acid_AMP_ligase BGC0000141.5 PKS 33.0 96.0 234.0 1.37e-69
AAM77987.1 adenylate_ligase BGC0000112.5 PKS:Iterative type I 32.0 97.3 234.0 1.4e-69
AAF08801.1 YngI BGC0001103.5 NRPS:Type I+PKS 30.0 98.4 233.0 2.23e-69
AEW31026.1 short-chain_acyl-CoA_synthetase BGC0000407.5 NRPS:Type I 30.0 98.2 233.0 3.12e-69
ADI58632.1 AsuB1 BGC0000187.5 PKS:Type II 34.0 96.6 240.0 7.02e-69
WP_069848012.1 salicylate_synthase BGC0002472.2 NRPS:Type I 31.0 96.9 238.0 2.56e-68
ADI58647.1 AsuD3 BGC0000187.5 PKS:Type II 35.0 86.9 227.0 6.95e-68
CAH10130.1 feruloyl-CoA_synthetase BGC0000268.5 PKS 32.0 90.3 226.0 5.74e-67
AAX98210.1 acyl_CoA_ligase BGC0000052.5 PKS 33.0 94.4 226.0 6.65e-67
CAJ45636.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000454.5 NRPS:Type I 29.0 95.3 224.0 4.01e-66
CAJ34366.1 putative_3-hydroxy-quinaldate-AMP-Ligase BGC0000445.5 NRPS:Type I 32.0 95.1 222.0 1.98e-65
BBD17745.1 AMP-ligase BGC0001918.3 NRPS:Type I+PKS 33.0 92.6 220.0 7.19e-65
ALK21567.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002678.2 NRPS:Type I 31.0 98.4 219.0 3.67e-64
MBE3200457.1 AMP-binding_protein BGC0002409.3 NRPS:Type I 32.0 96.4 218.0 8.06e-64
CCC55917.1 putative_acyl_CoA_ligase BGC0000973.5 NRPS:Type I+PKS:Type I 31.0 96.6 218.0 1.27e-63
AAO56101.1 yersiniabactin_synthetase,_salicylate_ligase_component BGC0002570.2 NRPS:Type I+PKS 31.0 93.7 214.0 1.5e-62
BAH04171.1 AMP-binding_ligase BGC0000450.5 NRPS:Type I 33.0 95.9 214.0 1.67e-62
AET98914.1 putative_AMP-binding_ligase BGC0000415.5 NRPS:Type I 32.0 96.2 214.0 3.24e-62
AAO07763.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000460.5 NRPS:Type I 30.0 96.9 212.0 2.33e-61
BAC16758.1 probable_2,3-dihydroxybenzoate-AMP_ligase_protein BGC0002474.2 NRPS:Type I 28.0 95.5 209.0 3.21e-60
CQR60497.1 Polyketide_synthase,_type_I,_modules:_loading,_1,_2_and_3 BGC0001287.5 PKS 32.0 94.4 213.0 5.6e-59
ABP55493.1 thioester_reductase_domain BGC0001006.5 NRPS:Type I+PKS 32.0 94.2 212.0 1.21e-58
ADM46356.1 polyketide_synthase BGC0000106.5 PKS 32.0 92.8 212.0 1.38e-58
ATY46587.1 polyketide_synthase BGC0001666.3 PKS 31.0 95.0 211.0 4.54e-58
QKW94281.1 long-chain-fatty-acid--CoA_ligase BGC0002342.3 NRPS:Type I+PKS 29.0 97.7 202.0 8.92e-58
AAQ84158.1 PlmJK BGC0000123.5 PKS 31.0 96.4 208.0 1.1e-57
ABV97151.1 AMP-dependent_synthetase_and_ligase BGC0000137.3 PKS 32.0 92.1 207.0 5.05e-57
ABV99085.1 thioester_reductase_domain BGC0001007.5 PKS+NRPS:Type I 31.0 92.4 206.0 1.1e-56
AAO07759.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000460.5 NRPS:Type I 27.0 96.4 197.0 4.81e-56
BAE98151.1 putative_AMP-binding_ligase BGC0000339.5 NRPS:Type I 31.0 96.4 197.0 6.53e-56
ABL70475.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002493.3 NRPS:Type I 30.0 97.7 196.0 1.17e-55
QBF51769.1 type_I_polyketide_synthase BGC0001856.4 PKS:Type I 31.0 92.1 203.0 1.65e-55
ACR50792.1 putative_acyl-CoA_synthase BGC0000163.5 PKS 28.0 93.5 193.0 1.09e-54
AKQ52536.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002533.2 NRPS:Type I+PKS 27.0 96.4 193.0 1.37e-54
CAA60460.1 polyketide_synthase BGC0001040.5 NRPS:Type I+PKS 31.0 95.1 200.0 1.58e-54
AAL65279.1 QbsL BGC0000925.5 other:other 30.0 97.5 198.0 2.76e-54
AAK95837.1 putative_2,3-dihydroxybenzoate-AMP-ligase_PhbE BGC0002495.2 NRPS:Type I 29.0 96.0 190.0 3.42e-53
ACR11042.1 Enterobactin_synthetase_component_E/2,3-dihydroxybenzoate-AMP_ligase BGC0000451.5 NRPS:Type I 27.0 96.4 188.0 1.07e-52
AAC68815.1 FK506_polyketide_synthase BGC0000353.5 NRPS:Type I 31.0 96.4 193.0 3.43e-52
WP_003060229.1 type_I_polyketide_synthase BGC0002009.4 PKS 33.0 92.6 192.0 6e-52
TXD00261.1 AMP-binding_protein BGC0001877.4 PKS 29.0 92.1 187.0 3.52e-50
AAC01710.1 RifA BGC0000136.5 PKS 31.0 92.1 187.0 5.31e-50
MBN3579117.1 AMP-binding_protein BGC0002613.2 NRPS:Type I+PKS 27.0 95.7 181.0 6.65e-50
AWH12671.1 RmpA1 BGC0001759.3 PKS 32.0 94.2 185.0 2.23e-49
CAI94682.1 putative_polyketide_synthase BGC0000141.5 PKS 30.0 94.6 184.0 3.22e-49
WP_028847739.1 AMP-binding_protein BGC0002467.2 NRPS:Type I 30.0 95.1 176.0 2.96e-48
AXM42922.1 AMP-dependent_synthetase_and_ligase/heterocyclase BGC0001940.3 PKS 31.0 85.6 176.0 1.98e-47
CAE17553.1 acyl_CoA_ligase BGC0000210.5 PKS:Type II+saccharide:oligosaccharide 29.0 94.1 173.0 2.7e-47
ACF35445.1 MbcAI BGC0000090.4 PKS 30.0 95.3 175.0 4.15e-46
BCJ07564.1 AMP-dependent_synthetase BGC0002379.3 NRPS:Type I 29.0 86.3 169.0 5.22e-46
AAF86393.1 FkbB BGC0000994.5 NRPS:Type I+PKS 29.0 96.2 175.0 5.63e-46
QIC03949.1 CyaA BGC0002347.3 other:other 30.0 87.8 168.0 1.46e-45
AFV52184.1 acyl-CoA_synthetase/P450_monooxygenase BGC0000081.5 NRPS:Type I+PKS:Iterative type I 31.0 93.3 172.0 1.97e-45
WP_015031692.1 type_I_polyketide_synthase BGC0001819.3 PKS 28.0 100.4 171.0 9.29e-45
CAE02600.1 putative_acyl-coA_ligase BGC0000024.5 PKS:Type I 29.0 95.1 164.0 4.05e-44
QTT72113.1 type_I_polyketide_synthase BGC0002350.2 NRPS:Type I+PKS+saccharide 29.0 93.0 166.0 3.38e-43
CAJ88630.1 putative_acyl-CoA_synthetase BGC0000327.5 NRPS:Type I 28.0 93.5 157.0 2.56e-41
AGM05527.1 AMP-dependent_synthetase_and_ligase BGC0002098.2 PKS 28.0 97.1 154.0 1.45e-40
ABC34346.1 long-chain-fatty-acid--CoA_ligase,_putative BGC0001102.5 NRPS:Type I+PKS:Type I 28.0 94.6 155.0 3.54e-40
CAG25758.1 putative_type_I_polyketide_synthase BGC0000311.6 saccharide+NRPS:Type I 30.0 84.7 149.0 2.81e-39
EFY99277.1 long-chain-fatty-acid--CoA_ligase BGC0002710.2 NRPS:Type I 26.0 94.6 151.0 4.85e-39
ASZ00147.1 polyketide_synthase BGC0001785.5 PKS 31.0 64.7 146.0 2.21e-36
PKY07881.1 hypothetical_protein BGC0001544.3 NRPS:Type I+PKS 27.0 96.0 144.0 6.49e-36
QED90620.1 AMP-dependent_ligase BGC0002081.3 PKS 27.0 93.0 138.0 1.66e-34
ABW00331.1 amino_acid_adenylation_domain BGC0000333.5 NRPS:Type I 27.0 97.3 138.0 1.03e-33
AIW82277.1 PuwA BGC0001125.5 NRPS:Type I+PKS 26.0 98.9 137.0 1.24e-33
WP_051729283.1 AMP-binding_protein BGC0002137.3 PKS 28.0 95.3 135.0 1.38e-33
AAC82549.1 FxbB BGC0000351.5 NRPS:Type I 27.0 95.7 134.0 1.24e-32
AXN93575.1 PuwA BGC0001950.4 NRPS:Type I 25.0 98.0 134.0 1.26e-32
AXN93584.1 PuwA BGC0001951.4 NRPS:Type I 25.0 98.0 134.0 1.26e-32
AIS24844.1 Dst22 BGC0001147.4 NRPS:Type I 29.0 65.1 132.0 1.29e-32
AHI59110.1 locillomycin_synthase_C BGC0001005.5 NRPS:Type I+PKS 24.0 94.8 133.0 3.78e-32
ACG60755.1 acyl-CoA_synthetase BGC0001058.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 28.0 71.4 127.0 5.31e-31
AGU50953.1 putative_non-ribosomal_peptide_synthetase BGC0002417.3 NRPS:Type I+PKS 24.0 95.5 129.0 8.65e-31
KGO40476.1 AMP-dependent_synthetase/ligase BGC0001205.3 PKS 29.0 63.7 122.0 1.63e-29
CAD91212.1 putative_non-ribosomal_peptide_synthetase,_modules_4-6 BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 27.0 94.6 125.0 1.82e-29
TXC99989.1 non-ribosomal_peptide_synthetase BGC0001877.4 PKS 26.0 96.8 122.0 6.81e-29
QVQ62857.1 AMP-binding_protein BGC0002373.3 NRPS:Type I 27.0 100.9 120.0 1.27e-28
CAC48361.1 peptide_synthetase BGC0000311.6 saccharide+NRPS:Type I 27.0 98.4 121.0 3.21e-28
QBF51786.1 Nrps BGC0001856.4 PKS:Type I 27.0 99.8 119.0 8.9e-28
AGD80618.1 non-ribosomal_peptide_synthetase BGC0000394.5 NRPS:Type I 25.0 96.0 118.0 1.92e-27
OAP25805.1 Long-chain-fatty-acid--CoA_ligase BGC0001658.3 PKS 25.0 91.7 116.0 2.09e-27
ACS20362.1 amino_acid_adenylation_domain_protein BGC0002420.3 NRPS:Type I+PKS 23.0 95.7 117.0 3.61e-27
CAG23957.2 NRPS/PKS_protein BGC0001089.5 NRPS:Type I+PKS:Type I 26.0 85.1 117.0 4.3e-27
ATP76245.1 SpuA BGC0001748.4 NRPS:Type I+PKS 27.0 90.3 117.0 4.41e-27
AOY81088.1 SDR_family_NAD(P)-dependent_oxidoreductase BGC0002754.2 NRPS:Type I 27.0 84.5 116.0 9.09e-27
AHJ31217.1 Long-chain-fatty-acid--CoA_ligase BGC0000430.5 NRPS:Type I+PKS:Type I 26.0 89.9 116.0 9.46e-27
AAT09804.1 NocA BGC0000395.5 NRPS:Type I 25.0 93.7 115.0 1.74e-26
ABP57748.1 DepD BGC0000993.4 NRPS:Type I+PKS:Type I 27.0 96.4 114.0 3.98e-26
QEO74904.1 AMP-dependent_synthetase_and_ligase BGC0002588.2 other:other 23.0 95.5 113.0 9.37e-26
ABL74936.1 TlmX BGC0001048.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 22.0 93.2 113.0 1.16e-25
ABM34280.1 amino_acid_adenylation_domain_protein BGC0002419.3 NRPS:Type I+PKS 25.0 90.5 110.0 1.08e-24
CCP42824.1 Possible_fatty-acid-CoA_ligase_FadD10_(fatty-acid-CoA_synthetase)_(fatty-acid-CoA_synthase) BGC0001627.4 NRPS:Type I 25.0 98.9 107.0 2e-24
BBD17759.1 non-ribosomal_peptide_synthetase BGC0001919.4 NRPS:Type I+PKS 27.0 78.4 109.0 2.23e-24
AWX24482.1 non-ribosomal_peptide_synthetase BGC0001695.5 NRPS:Type I 27.0 82.0 108.0 2.97e-24
AFY58521.1 amino_acid_adenylation_enzyme/thioester_reductase_family_protein BGC0002411.3 NRPS:Type I+PKS 22.0 96.2 107.0 9.98e-24
QDJ74293.1 peptide_synthetase BGC0002109.3 NRPS:Type I 27.0 92.6 105.0 1.81e-23
ABM21569.1 CrpA BGC0000975.5 NRPS:Type I+PKS 32.0 51.3 105.0 3.59e-23
EAU36837.1 predicted_protein BGC0002348.2 NRPS:Type I 29.0 54.1 104.0 3.95e-23
AWX24484.1 non-ribosomal_peptide_synthetase BGC0001695.5 NRPS:Type I 27.0 83.3 103.0 1.08e-22
ACD75096.1 MenE BGC0000913.3 other:other 25.0 87.2 101.0 1.2e-22
AQM58276.1 hypothetical_protein BGC0001816.4 NRPS:Type I+PKS 29.0 54.1 103.0 1.32e-22
AEU11005.1 NpnA BGC0001029.5 NRPS:Type I+PKS 28.0 57.7 101.0 8.46e-22
WP_081656241.1 non-ribosomal_peptide_synthetase BGC0001467.5 NRPS:Type I+PKS:Type I 27.0 87.9 100.0 2.36e-21
CDF96614.1 Long-chain-fatty-acid--CoA_ligase BGC0001149.5 NRPS:Type I+saccharide:hybrid/tailoring 23.0 93.5 99.0 4.17e-21
EJP62834.1 4-coumarate-CoA_ligase BGC0002203.2 NRPS:Type I+PKS+other:other 27.0 55.4 96.0 1.07e-20
AAY42397.1 HctE BGC0001000.5 NRPS:Type I+PKS:Type I 28.0 61.7 97.0 1.34e-20
AAY42398.1 HctF BGC0001000.5 NRPS:Type I+PKS:Type I 28.0 63.8 97.0 1.37e-20
ABY83140.1 Azi1 BGC0000960.5 NRPS:Type I+PKS 26.0 92.6 97.0 1.42e-20
BCB17035.1 acyl-CoA_ligase BGC0002523.2 NRPS:Type I 25.0 90.1 96.0 1.51e-20
ABA59547.1 Vlm1 BGC0000453.5 NRPS:Type I 27.0 79.9 95.0 7.23e-20
QWT72293.1 non-ribosomal_peptide_synthetase BGC0002430.3 NRPS:Type I+saccharide 24.0 98.7 94.0 1.2e-19
AGY62760.1 Orf1 BGC0000051.5 PKS 26.0 92.1 90.0 1.18e-18
SCN11954.1 Orf1_putative_non-ribosomal_peptide_synthetase BGC0001580.3 PKS 26.0 92.1 90.0 1.18e-18
ADH04681.1 non-ribosomal_peptide_synthetase BGC0001344.4 NRPS:Type I+PKS 27.0 88.1 91.0 1.22e-18
ATY37596.1 BogI BGC0001532.4 NRPS:Type I 27.0 55.8 91.0 1.39e-18
ARO38317.1 nonribosomal_peptide_synthetase BGC0001560.4 NRPS:Type I+PKS 24.0 84.0 91.0 2.17e-18
EAU36089.1 predicted_protein BGC0002273.2 NRPS:Type I 30.0 54.9 89.0 4.44e-18
CAE17538.1 acyl_CoA_ligase BGC0000210.5 PKS:Type II+saccharide:oligosaccharide 25.0 76.8 85.0 2.44e-17
PHM26612.1 pvdj BGC0001130.5 NRPS:Type I+PKS 23.0 64.7 85.0 1.03e-16
AQH32485.1 peptide_synthetase BGC0001667.4 NRPS:Type I+PKS 23.0 94.2 84.0 1.65e-16
RLV71193.1 non-ribosomal_peptide_synthetase BGC0001846.4 saccharide:hybrid/tailoring+NRPS:Type I 27.0 63.7 84.0 2.31e-16
pelB BGC0002056.3 NRPS:Type I+PKS:Trans-AT type I 26.0 58.5 80.0 1.29e-15
QNL34617.1 SteB BGC0002092.3 NRPS:Type I 24.0 82.7 81.0 2.86e-15
BAG84247.1 putative_L-prolyl-AMP_ligase BGC0000257.5 PKS:Type I 25.0 82.9 79.0 3.59e-15
ATP76243.1 NdaA BGC0001705.4 NRPS:Type I+PKS 23.0 93.9 76.0 5.67e-14
AAF00961.1 McyB BGC0001017.5 NRPS:Type I+PKS:Type I 23.0 94.4 76.0 7.25e-14
WP_064118560.1 non-ribosomal_peptide_synthetase BGC0001509.5 NRPS:Type I 24.0 82.9 76.0 1.03e-13
QCQ67880.1 non-ribosomal_peptide_synthetase BGC0002297.2 NRPS:Type I+PKS 22.0 94.4 75.0 1.26e-13
AAO62587.1 peptide_sythetase BGC0001016.5 NRPS:Type I+PKS 22.0 94.1 74.0 2.88e-13
AEO14743.1 NdaA BGC0000396.5 NRPS:Type I 22.0 94.8 74.0 3.91e-13
ABV56587.1 KtzG BGC0000378.5 NRPS:Type I 40.0 20.5 71.0 1.78e-12
QKW60398.1 non-ribosomal_peptide_synthetase BGC0002288.2 NRPS:Type I 26.0 69.6 70.0 4.54e-12
AGA37269.1 NRPS BGC0000819.5 NRPS:Type I+other:other 25.0 55.0 58.0 2.99e-08
CAC44647.1 phenylacetate-CoA_ligase BGC0002128.3 other:other 26.0 52.9 56.0 8.98e-08
AQW35054.1 long-chain_acyl-CoA_synthetase BGC0001675.5 PKS 25.0 79.5 55.0 1.77e-07
WP_047890612.1 class_I_adenylate-forming_enzyme_family_protein BGC0001330.5 NRPS:Type I+PKS:Type I 25.0 79.3 51.0 2.88e-06