LOCUS       NZ_PVRP01000014        24822 bp    DNA     linear   CON 22-NOV-2024
DEFINITION  Bacillus velezensis strain GBSW11 NODE_14_length_43355_cov_47.9109,
            whole genome shotgun sequence.
ACCESSION   NZ_PVRP01000014
VERSION     NZ_PVRP01000014.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus velezensis
  ORGANISM  Bacillus velezensis
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus; Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 43355)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Genotypic and phenotypic analysis of antagonistic Bacillus spp.
            isolated from rhizosphere soil of plants in Tibet
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 43355)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) UG, NordReet, Marienstr. 27a, Greifswald
            17489, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. A5-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 48.2x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002998915.1-RS_2024_11_20
            Annotation Date                   :: 11/20/2024 07:46:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,854
            CDSs (total)                      :: 3,748
            Genes (coding)                    :: 3,672
            CDSs (with protein)               :: 3,672
            Genes (RNA)                       :: 106
            rRNAs                             :: 8, 10, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 9, 2 (16S, 23S)
            tRNAs                             :: 80
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 42 of 76
            Pseudo Genes (incomplete)         :: 45 of 76
            Pseudo Genes (internal stop)      :: 7 of 76
            Pseudo Genes (multiple problems)  :: 16 of 76
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:10:33
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 18533
            Orig. end                         :: 43355
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVRP01000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24822
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..24822
                     /SMILES="NC(CS)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24822
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:>24822](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>24822
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(72..884)
                     /locus_tag="C6355_RS18730"
                     /old_locus_tag="C6355_18720"
     CDS             complement(72..884)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003152245.1"
                     /locus_tag="C6355_RS18730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18720"
                     /product="ABC transporter permease"
                     /protein_id="WP_106080461.1"
                     /transl_table=11
                     /translation="MKNSSGTIEQLHQQFKKRHQKEKLRIRAYQAAIFIVFFAGWEISS
                     RAGWIDPLIFSSPSAVCRLLVEKIADGSLAAHIGVTLGETVLGFLLGTFLGTCLAALLW
                     WSNRLARVLDPYLVILNAMPKVALGPILIVALGPNFTSIVAMGAVISVIITTIVVFTAF
                     QEVDENYIKVMKTFGAKRSIMFKEAILPACAPAIISALKVNVGLSWVGVIVGEFLVSEK
                     GLGYMIIYGFQVFNFTLVFLSLLIIAIFATLMYQGVELLERKWTKGKI"
     gene            complement(859..1641)
                     /locus_tag="C6355_RS18735"
                     /old_locus_tag="C6355_18725"
     CDS             complement(859..1641)
                     /EC_number="7.6.2.14"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016938481.1"
                     /locus_tag="C6355_RS18735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18725"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_007408831.1"
                     /transl_table=11
                     /translation="MSFLHVDHVTHTYFSLKEKTTAVKDIHFQIEKGDFISFLGPSGCG
                     KTTLLSILAGLITPAQGRVLIEGSVPNHKEHQIGYMLQQDYLFPWKSIEENVLLGLHIS
                     KTLTEEKRAEVLSLLPKLGLIGVEKKYPKELSGGMRQRAALARTLAPDPGLLLLDEPFS
                     ALDFQTKLSLENLVFRTLKDFQKTAVLVTHDIGEAIAMSDTIYLFSNQPGTIHQIFTVP
                     KELAALDPFDARQDPAFQPLFQTIWKELNSLEKQQRND"
     gene            complement(1653..2657)
                     /locus_tag="C6355_RS18740"
                     /old_locus_tag="C6355_18730"
     CDS             complement(1653..2657)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390937.2"
                     /locus_tag="C6355_RS18740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18730"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_007408830.1"
                     /transl_table=11
                     /translation="MNKWLKTGCVFVICAFFLLILPACRQEESLTKVKVAEVTHSIFYT
                     PLYVAEAKGFFKKEGLQVSLQTTWGGDKTMTSLLSNGSDIALIGSETSIYVEAQGAKDP
                     VINFAQLTQTDGTFLVSRKDEKSFKWSDLKGKTFLGQRKGGMPQMAGEYVLKKNHIEPK
                     KDINLVQNIDFANISNAFASGTGDYVQLFEPTASQFEKEGIGHIVASFGEASGQMPYTT
                     FMAKESYLKTNEKTAEKFTRAIYRAQQWVESHPAKDIAKTIQKEFADTDPAIIETSIER
                     YKKQKSFSADPVLQKDEWEQLQSIMDEAGELPKHIPYSKLVNTKIAKKVTSEQ"
     gene            2796..3569
                     /locus_tag="C6355_RS18745"
                     /old_locus_tag="C6355_18735"
     CDS             2796..3569
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390936.1"
                     /locus_tag="C6355_RS18745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18735"
                     /product="S9 family peptidase"
                     /protein_id="WP_106080462.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.4e-26, bitscore:
                     84.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAEKKRFPSPSPHIRLFEVCYESEGLKVKGLLAEPAAPGTYDGF
                     LYLRGGIKNVGMVRPGRIVQFASQGFVVFAPYYRGNQGGEGNEDFAGEDREDAFSAFRL
                     LREHPNVREGRVHIFGFSRGGIMGLLTAIEMRHQAASLVSWGGVSDMVLTYEERKDMRR
                     MMKRVIGGTPKKVPDEYRWRSPFENADRIQAPVLLIHGENDENVSIEHARMIEDKLKEA
                     GKPVETWYYSGFTHYFPPQENRRIVRRLAEWMKTR"
     misc_feature    3619..3633
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.88"
                     /tool="antismash"
     gene            3627..3869
                     /locus_tag="C6355_RS18750"
                     /old_locus_tag="C6355_18740"
     CDS             3627..3869
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1300: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390935.1"
                     /locus_tag="C6355_RS18750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18740"
                     /product="DUF2584 domain-containing protein"
                     /protein_id="WP_003152249.1"
                     /transl_table=11
                     /translation="MGMPVEFNTMIVTKGNEKRIEENIFLLEKEGYRVYPLDIPMDVRK
                     TKTGEKSGTGEVQKLEWANGRTSITYRLTSLHSTN"
     gene            complement(3912..5495)
                     /gene="pckA"
                     /locus_tag="C6355_RS18755"
                     /old_locus_tag="C6355_18745"
     CDS             complement(3912..5495)
                     /EC_number="4.1.1.49"
                     /GO_function="GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /gene="pckA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390934.2"
                     /locus_tag="C6355_RS18755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18745"
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="WP_106080463.1"
                     /transl_table=11
                     /translation="MKLVDLTADLQALLASPNVHHNLSAPKLTEKVISRNEGTLTSTGA
                     VRATTGAYTGRSPKDKFIVREQSTENQIDWGAVNQPISEEAFEKLYAKVVSYLKQRDEL
                     FVFDGFAGADEKYRLPITVVNEFAWHNLFARQLFIRPETNERDTQAQPFTILSAPHFKA
                     DPETDGTHSETFIIVSFEKRVILIGGTEYAGEMKKSIFSIMNFLLPQQDILPMHCSANV
                     GEKGDVALFFGLSGTGKTTLSADADRKLIGDDEHGWSDSGVFNIEGGCYAKCINLSEEK
                     EPQIFRAIRFGSVLENVVLDEKTGEADYDNSFYTENTRAAYPIEMIGNIVQPSIAGHPQ
                     AIVFLTADAFGVLPPISKLTKEQAMYHFLSGYTSKLAGTERGVTSPQTTFSTCFGSPFL
                     PLPAHVYAEMLGHKIDEHGVQVFLVNTGWTGGGYGVGERMKLSYTRAMVKAAIEGRLNQ
                     TDMTADSIFGLRSPVHVPGVPDEVLQPENTWSDKQAYNEKALFLANEFKENFKKFSHAD
                     SIAKAGGPLV"
     misc_feature    5675..5692
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     regulatory      5693..5832
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            6002..7204
                     /gene="metK"
                     /locus_tag="C6355_RS18760"
                     /old_locus_tag="C6355_18750"
     CDS             6002..7204
                     /EC_number="2.5.1.6"
                     /GO_function="GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="metK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390933.1"
                     /locus_tag="C6355_RS18760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18750"
                     /product="methionine adenosyltransferase"
                     /protein_id="WP_003152253.1"
                     /transl_table=11
                     /translation="MSKNRRLFTSESVTEGHPDKICDQISDSILDEILKNDPNARVACE
                     TSVTTGLVLVSGEITTSTYVDIPKTVRETIKEIGYTRAKYGFDAETCAVLTSIDEQSAD
                     IAMGVDQALEAREGTMSDAEIEAIGAGDQGLMFGYACNETKELMPLPISLAHKLARRLS
                     EVRKEDILPYLRPDGKTQVTVEYDENNKPVRIDAIVISTQHHPEITLEQIQRNLKEHVI
                     NPVVPEELIDEETKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKD
                     ATKVDRSAAYAARYVAKNIVAAGLADSCEVQLAYAIGVAQPVSISINTFDTGKASEEKL
                     IEVVRNNFDLRPAGIIKMLDLRRPIYKQTAAYGHFGRHDVDLPWERTDKADALRKEALG
                     E"
     gene            7348..9246
                     /gene="asnB"
                     /locus_tag="C6355_RS18765"
                     /old_locus_tag="C6355_18755"
     CDS             7348..9246
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390932.1"
                     /locus_tag="C6355_RS18765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18755"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_003152255.1"
                     /sec_met_domain="GATase_7 (E-value: 1.5e-47, bitscore:
                     152.0, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.8e-114, bitscore:
                     374.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGFVGVFNKHPLTQTADQEELIKQMNQMIVHRGPDSDGYYHDEH
                     VGFGFRRLSIIDVENGGQPLSYEDEKYWIIFNGEIYNYIELREELEAKGYTFNTDSDTE
                     VLLATYRHYKEEAASKLRGMFAFLIWNKADRVMYGARDPFGIKPLYYTTIGDKVYFASE
                     RKSLMAAQNGIDLDTASLQQYMSFQFVPEPSTLDAEVKKVEPGSQFTIRPEGDIAFKTY
                     FKANFKPVQSDEDKLVKEVRDAIFDSVKVHMRSDVPVGSFLSGGIDSSFIVSVAKEFHP
                     SLKTFSVGFEQQGFSEVDVAKETAAALGIENISKVISPEEYMNELPKIVWHFDDPLADP
                     AAIPLYFVAKEAKKHVTVALSGEGADELFGGYNIYREPLSLKPFERIPSGLKKMLLHVA
                     SVMPEGMRGKSLLVRGCTPLEERYIGNAKIFEEPVKKQLLKHYNPELSYRDVTKPYFTE
                     SRSYSDINKMQYVDIHTWMRGDILLKADKMTMANSLELRVPFLDKVVFDVASKIPDELK
                     TKNGTTKYLLRKAAEGVVPDHVLNRKKLGFPVPIRHWLKNEMNEWVRNIIRESETDAYI
                     EKDYVLQLLEDHCADRADNSRKIWTVLIFMIWHSINVEKRLVPEELNHQPKEVIFV"
     misc_feature    complement(9247..9262)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.03"
                     /tool="antismash"
     misc_feature    complement(9339..9353)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.65"
                     /tool="antismash"
     gene            9452..10855
                     /gene="alaP"
                     /locus_tag="C6355_RS18770"
                     /old_locus_tag="C6355_18760"
     CDS             9452..10855
                     /codon_start=1
                     /gene="alaP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007408827.1"
                     /locus_tag="C6355_RS18770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18760"
                     /product="alanine permease AlaP"
                     /protein_id="WP_017418420.1"
                     /transl_table=11
                     /translation="MQNKEKTLHRGLEERHISLMSLGAAIGVGLFLGSASAIKLAGPGI
                     LAAYACSGLIMFFIMRALGEMAIQKPVAGSFSRYARDYLGPLAGFLTGWNYWFLWVVTC
                     MAEITAVGIYMGYWFPDVPSWIWALCALVIMTAVNFLAVKAYGELEFWFALIKVLAILS
                     MIAIGLVMIVFGLGNGGVALGISNLWSHGGFFPNGIKGVLLSLQMVMFAYLGIELIGVT
                     AGEVKNPEKSLARAIDTVFWRILIFYVGALFVIMSIYPWQEIGSGGSPFVLTFEKIGIP
                     AAAGIINFVVLTAALSSCNSGIFSTGRMLFNLAEQNEAPKAYGTVTKGGVPGKAVLVSA
                     GALCIGVLLNYVVPAKVFTWVTSIATFGAIWTWSIILLSQMKYRKSLQPEQRKKLKYKM
                     PLYPFSSYISLAFLAFVVVLMAFDAETRVAVIIGPVWFGILLAAYYGKGFHKRKDIGLE
                     NGQTFAEKA"
     gene            complement(11032..11547)
                     /locus_tag="C6355_RS18775"
                     /old_locus_tag="C6355_18765"
     CDS             complement(11032..11547)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003324958.1"
                     /locus_tag="C6355_RS18775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18765"
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="WP_025285156.1"
                     /transl_table=11
                     /translation="MIYPYKQFTPDIHPEAFIADNAVITGDVVIGEQSSIWFSAVIRGD
                     VAPTRIGKRVSIQDLSCLHQSPNRPLLIEDDVTIGHQVTLHSAIIKKNALIGMGSVILD
                     GAEIGEGAFIGAGSLVPPGKTIPPGCLAFGRPAKVIRRLTEEDIRDMERIRTEYVEKGR
                     YYKTLQEK"
     gene            11594..12373
                     /locus_tag="C6355_RS18780"
                     /old_locus_tag="C6355_18770"
     CDS             11594..12373
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (11-127). E-value:
                     1.3e-15. Score: 49.6. Matches aSDomain:
                     nrpspksdomains_C6355_RS18780_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390929.1"
                     /locus_tag="C6355_RS18780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18770"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_003152261.1"
                     /sec_met_domain="PF00561 (E-value: 2.6e-14, bitscore: 44.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.6e-15, bitscore:
                     49.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWTWKADRPVGTIVIIHGASEYHGRYKWLVEMWRSSGYNVVMGDL
                     PGQGTSTRARGHIRSFQEYIDEVDIWIDKARTLEAPVFLLGHSMGGLIAIEWFKQQRNP
                     RITALILSSPCLGLQIKVNKVLDFASKGLNVLAPSLRVDSGLSPDMATRNADMIEADQN
                     DSLYVTKVSVRWYRELLKTIDAAMVPTDAFLKVPLLLMQGGDDKIVDKMKVRKWFSGVA
                     SHNKSYREWEGLYHEIFNEPERETVFKAAKAFTDQYI"
     aSDomain        11627..11974
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6355_RS18780_Abhydrolase_1.1"
                     /evalue="1.30E-15"
                     /label="C6355_RS18780_Abhydrolase_1.1"
                     /locus_tag="C6355_RS18780"
                     /protein_end="127"
                     /protein_start="11"
                     /score="49.6"
                     /tool="antismash"
                     /translation="TIVIIHGASEYHGRYKWLVEMWRSSGYNVVMGDLPGQGTSTRARG
                     HIRSFQEYIDEVDIWIDKARTLEAPVFLLGHSMGGLIAIEWFKQQRNPRITALILSSPC
                     LGLQIKVNKVLD"
     CDS_motif       11831..11881
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18780_0001"
                     /evalue="1.20E-06"
                     /label="NRPS-te1"
                     /locus_tag="C6355_RS18780"
                     /protein_end="96"
                     /protein_start="79"
                     /score="21.0"
                     /tool="antismash"
                     /translation="APVFLLGHSMGGLIAIE"
     gene            12394..13473
                     /locus_tag="C6355_RS18785"
                     /old_locus_tag="C6355_18775"
     CDS             12394..13473
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013353263.1"
                     /locus_tag="C6355_RS18785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18775"
                     /product="tetraprenyl-beta-curcumene synthase family
                     protein"
                     /protein_id="WP_007408825.1"
                     /transl_table=11
                     /translation="MTVPEHPFNLMAKVYREIFPLVHQELNMWREKSDSIKNTELRQQA
                     AASIRDKSFHCEGGGILALLSGEQKQKCVQFIIAYQTISDYLDNLCDRSTSLDPEDFRM
                     LHLSMRDALTVGAEVRPYYQYRDEQDDGGYLHELVRTCQRVLGSIEHYGIIKPYLLELC
                     DYYCDLQVHKHVVEHERVPRLKGWFEQYRSQLPEMEWFEFSACAGSTLGIFCLVAYSFQ
                     PDFNEHTAEKIRSSYFPYIQGLHILLDYLIDQEEDLLEGDLNFCTYYQSHEEMMQRLQH
                     FIEKADEHLQGIPHENFHRLINRGLLGVYLSDDKVAGQKEMGRLARKLIRASGKTSFFF
                     YINGRAYRKFQKMAWTKSS"
     misc_feature    complement(13578..13592)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.76"
                     /tool="antismash"
     misc_feature    13579..13592
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(13580..13593)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            13584..14393
                     /locus_tag="C6355_RS18790"
                     /old_locus_tag="C6355_18780"
     CDS             13584..14393
                     /GO_function="GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017418417.1"
                     /locus_tag="C6355_RS18790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18780"
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="WP_106080464.1"
                     /transl_table=11
                     /translation="MKKLKYLAVIALLSISGGCSVIHASAGYHPVLIAHRGSSAIEPEH
                     TALSYARAIKDKADYIEIDLRKTKDGHLIAIHDKTVDRTTDGKGMTDDLSLAQIKKLNA
                     GKGEKILTLEEIIQKFGQTANYYIETRESNGSLVMEKKLIDILQKHKLISSHKAVIESF
                     SGKSLKKVRSMDKKVPLVRLLKDNEAEEINDKQLQTIRTYADTVGLNAKLANEAVVKCI
                     HHNKMKVHVFFDKEDEHTLTPIMLKQKADGVFTNNPAYTRGVLQNSK"
     gene            complement(14411..14605)
                     /locus_tag="C6355_RS18795"
                     /old_locus_tag="C6355_18785"
     CDS             complement(14411..14605)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014470848.1"
                     /locus_tag="C6355_RS18795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18785"
                     /product="hypothetical protein"
                     /protein_id="WP_003152265.1"
                     /transl_table=11
                     /translation="MNILRIIFSSVPYVMFVIILSRHLGFEFAKTYYWWFAAFFVIGLI
                     GKFAMHLAAKKKPLKKETA"
     misc_feature    14671..14684
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.84"
                     /tool="antismash"
     misc_feature    14671..14685
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.59"
                     /tool="antismash"
     gene            complement(14728..15309)
                     /locus_tag="C6355_RS18800"
                     /old_locus_tag="C6355_18790"
     CDS             complement(14728..15309)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003152267.1"
                     /locus_tag="C6355_RS18800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18790"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_007408823.1"
                     /transl_table=11
                     /translation="MTLMHILPFSKELLKSAAQEGDITVDATMGNGHDTYFLAGLVGET
                     GHVHAFDIQADALAKTKERLGADFSPRVTLHHKSHDQIKASLPEDAHGRVACAVFNLGY
                     LPGGDKSITTNGHSTISAIEQLLELLKENGMIVLVVYHGHPEGKTEKSALLEYCSNLDQ
                     EKARVLSYGFLNQRNDPPFIIAIEKKSAGK"
     gene            complement(15306..16274)
                     /locus_tag="C6355_RS18805"
                     /old_locus_tag="C6355_18795"
     CDS             complement(15306..16274)
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390926.1"
                     /locus_tag="C6355_RS18805"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; This family includes
                     YhcC from E. coli K-12, an uncharacterized radical SAM
                     protein; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18795"
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="WP_007408822.1"
                     /sec_met_domain="PF04055 (E-value: 7.2e-17, bitscore: 53.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNENNPFPYSNTEKRYHTLNYHLREHFGHKVFKVALDGGFDCPNR
                     DGTVAHGGCTFCSAAGSGDFAGNRADDLLTQFHDIKNRMHEKWKDGKYIAYFQAFTNTH
                     APVEELREKFESVLKLDGVVGMSIATRPDCLPDDVVEYLAELNERTYLWVELGLQTVHE
                     RTALLINRAHDFDCYVEGVNKLRKHGIRVCSHIINGLPLENRDMMMETAKAVADLDVQG
                     IKIHLLHLLKGTPMVKQYEKGKLEFLSQEEYVSLVCDQLEIIPPEMIVHRITGDGPIEL
                     MVGPMWSVNKWEVLGAIQKELETRGSYQGKLFRKIGEETAL"
     gene            complement(16361..18028)
                     /locus_tag="C6355_RS18810"
                     /old_locus_tag="C6355_18800"
     CDS             complement(16361..18028)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012118253.1"
                     /locus_tag="C6355_RS18810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18800"
                     /product="MFS transporter"
                     /protein_id="WP_076425159.1"
                     /transl_table=11
                     /translation="MNFKKIIMLSALLLGTFISVMDTTIVNIALPKMLDYFSSNLSQVA
                     WVATGYTLAFAVLLVGASKLADHFGRKKAFMFGLALFILTSVIACLSTSIEMLVTIRVI
                     QGLSAAFIVPVTMPIALAIVPQNKKGMIIGIWGAFSGLAATLGPVLGGLLTENFNWQAI
                     FFINIPLGLISLFLAAFFITESYDETVSKKIDYMGILILSGALFCLTFGFAKVSDLGWS
                     SPLIISLFVISVLLFCLFFFIESKIKNPMIPLSMLKIRTFSFSSFTLFMQGLGLTSGTL
                     IITLLLTNLMGKTELEAGLIVSTLALSSMFTSVLSGKLSDKLGGIWLSGLGMLGLTITT
                     YLYGYIRYDSSITSVIILLCLTGLALGLVIGPAMSSGIRLIPPEKVGIASGILNMMRTV
                     GQALGIAILTSVLTMNINDHTATAKKEAIKIVESNQVFDKNAKNEIITHLKHSDSKGFD
                     RSKSIAELNKKEEEILSITPDPYKEKVQKSFNIQKKEVMAIQKKISNLYNEKISDSFNN
                     TFKVGSVILILGIIFALFSDISPKRLKQQQKNQVDITS"
     misc_feature    complement(18149..18165)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.87"
                     /tool="antismash"
     misc_feature    complement(18270..18283)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.69"
                     /tool="antismash"
     misc_feature    complement(18271..18284)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.84"
                     /tool="antismash"
     gene            18294..18998
                     /locus_tag="C6355_RS18815"
                     /old_locus_tag="C6355_18805"
     CDS             18294..18998
                     /NRPS_PKS="Domain: Thioesterase (5-232). E-value: 1.7e-41.
                     Score: 135.1. Matches aSDomain:
                     nrpspksdomains_C6355_RS18815_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.5"
                     /locus_tag="C6355_RS18815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18805"
                     /product="thioesterase II family protein"
                     /protein_id="WP_039063503.1"
                     /sec_met_domain="Thioesterase (E-value: 6.7e-44, bitscore:
                     142.1, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPIKLFCIPHAGGLSSIYSEWSNSVGPEIELIPVELAGRGSRF
                     SENPYKTINQAIDDITELILRKCDNKCYAIYGHSMGAYISYEVILKLMKVTDNLPQHLF
                     VSGKGAPYLTKETFISGLPDKQVIQWLNKLGGIPKELIENYELMKLFLPVIRNDYKLIE
                     SYNHNIKKKLSNVTLTVLTGKFDESITIGEVEGWKEYSAKEVDVYQISGGHFFINESVT
                     EVISIIKDKLLV"
     aSDomain        18309..18989
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6355_RS18815_Thioesterase.1"
                     /evalue="1.70E-41"
                     /label="C6355_RS18815_Thioesterase.1"
                     /locus_tag="C6355_RS18815"
                     /protein_end="232"
                     /protein_start="5"
                     /score="135.1"
                     /tool="antismash"
                     /translation="KLFCIPHAGGLSSIYSEWSNSVGPEIELIPVELAGRGSRFSENPY
                     KTINQAIDDITELILRKCDNKCYAIYGHSMGAYISYEVILKLMKVTDNLPQHLFVSGKG
                     APYLTKETFISGLPDKQVIQWLNKLGGIPKELIENYELMKLFLPVIRNDYKLIESYNHN
                     IKKKLSNVTLTVLTGKFDESITIGEVEGWKEYSAKEVDVYQISGGHFFINESVTEVISI
                     IKDKL"
     CDS_motif       18510..18557
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18815_0001"
                     /evalue="2.00E-04"
                     /label="NRPS-te1"
                     /locus_tag="C6355_RS18815"
                     /protein_end="88"
                     /protein_start="72"
                     /score="13.9"
                     /tool="antismash"
                     /translation="YAIYGHSMGAYISYEV"
     gene            19021..20004
                     /locus_tag="C6355_RS18820"
                     /old_locus_tag="C6355_18810"
     CDS             19021..20004
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013077.5"
                     /locus_tag="C6355_RS18820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18810"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_012118251.1"
                     /sec_met_domain="PF00881 (E-value: 2.4e-19, bitscore: 61.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKYFWAPHVHWRNENNHIIINDFQFRGKVVELFPDIYFHFQKGI
                     SLSEIYVIFKDFNPKILKMFLKDLIRNRVLVCNVSTPTELFETQNKFVYQEYDDEFFLY
                     KENIESYKKKQLTRFMSKNTLQSIDLEECSDLPSLVQNRKSTRNFDTSKMMNFSKFSRL
                     LNVFKQSPIQEGIKYFYPSAGGLYPVNIYLYIKDGRVENLEEGIYFYNPHSHSINLLNR
                     VKLAEKKYHYFINHSAFNTSNFSIFFTLDCDVIMPKYKGAGYYYGILECGVMSATLANI
                     AEYFDVGSCSIGEIDFDKIKDEFNLNSNEIYLHSVEVGLKNKEVNH"
     gene            20001..>24822
                     /locus_tag="C6355_RS18825"
                     /old_locus_tag="C6355_18815"
     CDS             20001..>24822
                     /NRPS_PKS="Domain: PP-binding (25-80). E-value: 3.1e-08.
                     Score: 25.8. Matches aSDomain:
                     nrpspksdomains_C6355_RS18825_PP-binding.1"
                     /NRPS_PKS="Domain: Heterocyclization (107-400). E-value:
                     2.1e-86. Score: 282.0. Matches aSDomain:
                     nrpspksdomains_C6355_RS18825_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (560-951). E-value: 6.1e-98.
                     Score: 320.0. Matches aSDomain:
                     nrpspksdomains_C6355_RS18825_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1060-1128). E-value: 1.1e-18.
                     Score: 59.2. Matches aSDomain:
                     nrpspksdomains_C6355_RS18825_PCP.1"
                     /NRPS_PKS="Domain: Heterocyclization (1150-1445). E-value:
                     1.3e-91. Score: 299.0. Matches aSDomain:
                     nrpspksdomains_C6355_RS18825_Heterocyclization.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="C6355_RS18825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6355_18815"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_142396297.1"
                     /sec_met_domain="AMP-binding (E-value: 9.7e-108, bitscore:
                     351.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.2e-15, bitscore:
                     47.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.1e-55, bitscore:
                     180.2, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINNTLVTSNKFKEISNFIIKKIRELSKDDSVDLRTNIFDYQISS
                     INILKLLGAIEDTYNINIEFYDYIDNPDVLSFCQVVYEKFQLLDNKKEYNILHLLSDEE
                     NAYKEFDLTNVQVAYLSGRDKQFELGGTSTHAFVEFEAELDIEKFNKSVQAVIERQHML
                     RAVFLSNGKQKILEHVPNYKLAIQDVSYLKKSDQEDKILEARKVTNERIFDPYQWPLFE
                     FKALKISDKLYRIFFDIDMLIADGASIQLLFKEISELYNGKIQEPLEVSYRDYMLAYNK
                     LKGNHKYQDDKEYWLNKLKSFPSTPALPVKVDLACIKKPTFKRKKKIIEKRNWNQFVNL
                     CSRKNIRPSILLLSIYSKVLSKWSNQQNIALNTTLFKRRPLHKQINNVIGDFTEIMIFD
                     VCFNNLNHFWEEVKNIQDNFFKCLSHNDFDGIEFTREYCEFNDIDRRKAVFPIVFTSML
                     FENELNYLDSLGVFIESISQTSQVYLDHQVIELNDGVMLSWDYVSEAFENDVIESMFEE
                     YTHIIDQLTSGEMMSSEDTALEQAITDYNQTEKAIKPDTLYHLFARQTIKTPENIAIEC
                     QGRAVTYQELQVMSNRISSFLEEKGIQPNEYVGVIVDREIETIASILAVLKIGAAYIPI
                     NPEFPKERQSYILKDGDCKVVLTAELAKTIVSSYKESKRESVAVPEQIAYAIYTSGSTG
                     KPKGVIIKNEAVTNTILDINEKYSVNETDRFIGLSSMSFDLSIYDIFGAFSAGATLVMI
                     EDQRDIKKIHDIVKEEKITVWNSVPMIMEMLVNYMDETENKSNAGVINYDELPELRLVL
                     LSGDWIPVHLPERIKDHFVESEVISLGGATEASIWSIYYPIKTVKAEWTSIPYGYPLSN
                     QTYYVLNYENDPCPIGVKGELYIGGKGVADGYLNDKEKTEASFIDHPDFGRIYRTGDMG
                     VLTQEGYIEFLGRKDHQIKVRGYRVELGEIESVILEHRQVRNAVVINQKDARNQDVLYA
                     YVTGHQSLPPTDLKEFLSLKVPEYMIPSYIVQIEEVPLTSNGKVDRKKLLALDVTDQAS
                     IGRKIKEPRTEIERDLVGIWKSVLKTNEISIDDNFFELGGNSILIINLITAIEDRLFIK
                     LDFKNFISNSTIEKLAKVISVSERKSKTNSNVMEIQADIKHKNTEFDLTNVQMAYLMGR
                     DKQFELGGTSTHAYLEIETELNIEKLNKSLQKVIDHQDMLRAVILPNGRQKILQQVPQY
                     EISVQDISQLSDIEQEKKIAEERDRTSHHIFNPNEWPLFEFKALKIQGDKHRLFFDIDM
                     LIADGASIQLLFKQISELYNGKDEMVPLEISYRDYMLAYQKVKTTQKYENDKAYWLSQL
                     EDFPKAPAVPLKERLDAISKPTFKRKSKIIDKLLWETLCKKAASYNITPAIILFTAYAK
                     VLSKWSNQQNLAVNTTVFNRQPLHKQVNDIIGDFTSLIMLKASFEKKMNFWEEAKKVQV
                     TFMEALEHRDYDGVEFIREYARYNNLKHKSATMPVVFTSMLFGNMFNLNNNDLLNIGEL
                     KMAVSQTSQVYLDHQVIELNDGVMLSWDYVSEAFENDVIESMFEEYTHIIDQLTSGEMM
                     SSEDTALEQAITDYNQTEKAIKPDTLYH"
     aSDomain        20076..20240
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6355_RS18825_PP-binding.1"
                     /evalue="3.10E-08"
                     /label="C6355_RS18825_PP-binding.1"
                     /locus_tag="C6355_RS18825"
                     /protein_end="80"
                     /protein_start="25"
                     /score="25.8"
                     /tool="antismash"
                     /translation="LSKDDSVDLRTNIFDYQISSINILKLLGAIEDTYNINIEFYDYID
                     NPDVLSFCQV"
     aSDomain        20322..21200
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6355_RS18825_Heterocyclization.
                     1"
                     /evalue="2.10E-86"
                     /label="C6355_RS18825_Heterocyclization.1"
                     /locus_tag="C6355_RS18825"
                     /protein_end="400"
                     /protein_start="107"
                     /score="282.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DMLIADG"
                     /tool="antismash"
                     /translation="KEFDLTNVQVAYLSGRDKQFELGGTSTHAFVEFEAELDIEKFNKS
                     VQAVIERQHMLRAVFLSNGKQKILEHVPNYKLAIQDVSYLKKSDQEDKILEARKVTNER
                     IFDPYQWPLFEFKALKISDKLYRIFFDIDMLIADGASIQLLFKEISELYNGKIQEPLEV
                     SYRDYMLAYNKLKGNHKYQDDKEYWLNKLKSFPSTPALPVKVDLACIKKPTFKRKKKII
                     EKRNWNQFVNLCSRKNIRPSILLLSIYSKVLSKWSNQQNIALNTTLFKRRPLHKQINNV
                     IGDFTEIMIFDV"
     aSModule        20322..23384
                     /complete
                     /domains="nrpspksdomains_C6355_RS18825_Heterocyclization.1"
                     /domains="nrpspksdomains_C6355_RS18825_AMP-binding.1"
                     /domains="nrpspksdomains_C6355_RS18825_PCP.1"
                     /locus_tags="C6355_RS18825"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20412..20504
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0001"
                     /evalue="1.70E-05"
                     /label="C2_DCL_024-062"
                     /locus_tag="C6355_RS18825"
                     /protein_end="168"
                     /protein_start="137"
                     /score="17.1"
                     /tool="antismash"
                     /translation="VEFEAELDIEKFNKSVQAVIERQHMLRAVFL"
     CDS_motif       20700..20744
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0002"
                     /evalue="3.00E-05"
                     /label="Cy3"
                     /locus_tag="C6355_RS18825"
                     /protein_end="248"
                     /protein_start="233"
                     /score="17.2"
                     /tool="antismash"
                     /translation="RIFFDIDMLIADGAS"
     CDS_motif       21042..21092
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0003"
                     /evalue="2.50E-03"
                     /label="Cy4"
                     /locus_tag="C6355_RS18825"
                     /protein_end="364"
                     /protein_start="347"
                     /score="10.9"
                     /tool="antismash"
                     /translation="PSILLLSIYSKVLSKWS"
     CDS_motif       21108..21143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0004"
                     /evalue="7.60E-02"
                     /label="afterCy4"
                     /locus_tag="C6355_RS18825"
                     /protein_end="381"
                     /protein_start="369"
                     /score="6.2"
                     /tool="antismash"
                     /translation="ALNTTLFKRRPL"
     CDS_motif       21144..21200
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0005"
                     /evalue="1.90E-05"
                     /label="Cy5"
                     /locus_tag="C6355_RS18825"
                     /protein_end="400"
                     /protein_start="381"
                     /score="17.1"
                     /tool="antismash"
                     /translation="HKQINNVIGDFTEIMIFDV"
     CDS_motif       21267..21308
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0006"
                     /evalue="1.00E-01"
                     /label="afterCy5"
                     /locus_tag="C6355_RS18825"
                     /protein_end="436"
                     /protein_start="422"
                     /score="6.0"
                     /tool="antismash"
                     /translation="LSHNDFDGIEFTRE"
     CDS_motif       21348..21374
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0007"
                     /evalue="7.40E-02"
                     /label="Cy6"
                     /locus_tag="C6355_RS18825"
                     /protein_end="458"
                     /protein_start="449"
                     /score="6.4"
                     /tool="antismash"
                     /translation="FPIVFTSML"
     CDS_motif       21426..21500
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0008"
                     /evalue="3.70E-05"
                     /label="Cy7"
                     /locus_tag="C6355_RS18825"
                     /protein_end="500"
                     /protein_start="475"
                     /score="16.7"
                     /tool="antismash"
                     /translation="ISQTSQVYLDHQVIELNDGVMLSWD"
     aSDomain        21681..22853
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6355_RS18825_AMP-binding.1"
                     /evalue="6.10E-98"
                     /label="C6355_RS18825_AMP-binding.1"
                     /locus_tag="C6355_RS18825"
                     /protein_end="951"
                     /protein_start="560"
                     /score="320.0"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FARQTIKTPENIAIECQGRAVTYQELQVMSNRISSFLEEKGIQPN
                     EYVGVIVDREIETIASILAVLKIGAAYIPINPEFPKERQSYILKDGDCKVVLTAELAKT
                     IVSSYKESKRESVAVPEQIAYAIYTSGSTGKPKGVIIKNEAVTNTILDINEKYSVNETD
                     RFIGLSSMSFDLSIYDIFGAFSAGATLVMIEDQRDIKKIHDIVKEEKITVWNSVPMIME
                     MLVNYMDETENKSNAGVINYDELPELRLVLLSGDWIPVHLPERIKDHFVESEVISLGGA
                     TEASIWSIYYPIKTVKAEWTSIPYGYPLSNQTYYVLNYENDPCPIGVKGELYIGGKGVA
                     DGYLNDKEKTEASFIDHPDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVR"
     CDS_motif       21867..21905
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0009"
                     /evalue="1.00E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="C6355_RS18825"
                     /protein_end="635"
                     /protein_start="622"
                     /score="12.6"
                     /tool="antismash"
                     /translation="LAVLKIGAAYIPI"
     CDS_motif       22050..22106
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0010"
                     /evalue="1.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="C6355_RS18825"
                     /protein_end="702"
                     /protein_start="683"
                     /score="26.7"
                     /tool="antismash"
                     /translation="AYAIYTSGSTGKPKGVIIK"
     CDS_motif       22653..22742
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0011"
                     /evalue="6.80E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="C6355_RS18825"
                     /protein_end="914"
                     /protein_start="884"
                     /score="44.0"
                     /tool="antismash"
                     /translation="PIGVKGELYIGGKGVADGYLNDKEKTEASF"
     CDS_motif       22818..22883
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0012"
                     /evalue="3.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="C6355_RS18825"
                     /protein_end="961"
                     /protein_start="939"
                     /score="38.3"
                     /tool="antismash"
                     /translation="FLGRKDHQIKVRGYRVELGEIE"
     aSDomain        23181..23384
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6355_RS18825_PCP.1"
                     /evalue="1.10E-18"
                     /label="C6355_RS18825_PCP.1"
                     /locus_tag="C6355_RS18825"
                     /protein_end="1128"
                     /protein_start="1060"
                     /score="59.2"
                     /tool="antismash"
                     /translation="ERDLVGIWKSVLKTNEISIDDNFFELGGNSILIINLITAIEDRLF
                     IKLDFKNFISNSTIEKLAKVISV"
     aSDomain        23451..24335
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6355_RS18825_Heterocyclization.
                     2"
                     /evalue="1.30E-91"
                     /label="C6355_RS18825_Heterocyclization.2"
                     /locus_tag="C6355_RS18825"
                     /protein_end="1445"
                     /protein_start="1150"
                     /score="299.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DMLIADG"
                     /tool="antismash"
                     /translation="TEFDLTNVQMAYLMGRDKQFELGGTSTHAYLEIETELNIEKLNKS
                     LQKVIDHQDMLRAVILPNGRQKILQQVPQYEISVQDISQLSDIEQEKKIAEERDRTSHH
                     IFNPNEWPLFEFKALKIQGDKHRLFFDIDMLIADGASIQLLFKQISELYNGKDEMVPLE
                     ISYRDYMLAYQKVKTTQKYENDKAYWLSQLEDFPKAPAVPLKERLDAISKPTFKRKSKI
                     IDKLLWETLCKKAASYNITPAIILFTAYAKVLSKWSNQQNLAVNTTVFNRQPLHKQVND
                     IIGDFTSLIMLKAS"
     CDS_motif       23595..23648
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0013"
                     /evalue="6.50E-06"
                     /label="Cy2"
                     /locus_tag="C6355_RS18825"
                     /protein_end="1216"
                     /protein_start="1198"
                     /score="18.6"
                     /tool="antismash"
                     /translation="VIDHQDMLRAVILPNGRQ"
     CDS_motif       23829..23873
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0014"
                     /evalue="1.50E-05"
                     /label="Cy3"
                     /locus_tag="C6355_RS18825"
                     /protein_end="1291"
                     /protein_start="1276"
                     /score="18.1"
                     /tool="antismash"
                     /translation="RLFFDIDMLIADGAS"
     CDS_motif       24165..24224
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0015"
                     /evalue="3.80E-05"
                     /label="Cy4"
                     /locus_tag="C6355_RS18825"
                     /protein_end="1408"
                     /protein_start="1388"
                     /score="16.6"
                     /tool="antismash"
                     /translation="NITPAIILFTAYAKVLSKWS"
     CDS_motif       24240..24275
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0016"
                     /evalue="7.80E-03"
                     /label="afterCy4"
                     /locus_tag="C6355_RS18825"
                     /protein_end="1425"
                     /protein_start="1413"
                     /score="9.2"
                     /tool="antismash"
                     /translation="AVNTTVFNRQPL"
     CDS_motif       24276..24326
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0017"
                     /evalue="1.00E-06"
                     /label="Cy5"
                     /locus_tag="C6355_RS18825"
                     /protein_end="1442"
                     /protein_start="1425"
                     /score="21.0"
                     /tool="antismash"
                     /translation="HKQVNDIIGDFTSLIML"
     CDS_motif       24396..24440
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0018"
                     /evalue="2.20E-04"
                     /label="afterCy5"
                     /locus_tag="C6355_RS18825"
                     /protein_end="1480"
                     /protein_start="1465"
                     /score="14.1"
                     /tool="antismash"
                     /translation="ALEHRDYDGVEFIRE"
     CDS_motif       24480..24506
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0019"
                     /evalue="9.80E-03"
                     /label="Cy6"
                     /locus_tag="C6355_RS18825"
                     /protein_end="1502"
                     /protein_start="1493"
                     /score="8.9"
                     /tool="antismash"
                     /translation="MPVVFTSML"
     CDS_motif       24570..24644
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6355_RS18825_0020"
                     /evalue="5.30E-05"
                     /label="Cy7"
                     /locus_tag="C6355_RS18825"
                     /protein_end="1548"
                     /protein_start="1523"
                     /score="16.3"
                     /tool="antismash"
                     /translation="VSQTSQVYLDHQVIELNDGVMLSWD"
ORIGIN
        1 gaaaaagctg aaagaggacg gcgtatttca atcataaaaa cgaagacccg gcgtttacgc
       61 acgggtcttt tttaaatttt tcctttcgtc cattttcttt ctaacagttc gactccctga
      121 tacatcaatg tcgcaaaaat tgcgatgatc agaaggctta agaacacaag agtgaaattg
      181 aagacctgga atccgtaaat gatcatgtag cccagacctt tttcggaaac gagaaactcg
      241 ccgacgatga caccgaccca ggataaaccg acgttcactt taagcgcgga aataatcgcg
      301 ggagcgcatg ccggcagaat ggcttcttta aacatgatgc ttcttttcgc tccgaaggtt
      361 ttcatcactt taatatagtt ttcatccact tcctgaaaag ccgtaaagac gacgattgtc
      421 gtgataatga cactgatgac tgctcccatg gcgacaatgc ttgtgaaatt cggtccgagt
      481 gccacgatga gaatcggtcc gagtgcgacc ttcggcatcg cgtttaaaat gacgaggtac
      541 gggtctaaaa cccgggcgag cctgtttgac caccataaca gagcggcgag gcatgtgccg
      601 agaaacgtgc cgagcaaaaa gccgagaacg gtttccccta aggttacgcc gatgtgcgcc
      661 gcaagggatc cgtccgcaat cttttcaact aaaagcctgc aaacggcgga gggtgagctg
      721 aagattaacg gatcgatcca gcccgccctg ctcgatattt cccatccggc aaaaaatacg
      781 ataaaaatgg cggcctgata cgcacggatc cggagctttt ctttttggtg tcttttctta
      841 aactgctgat gaagctgttc aatcgttccg ctgctgtttt tcaagggaat tcagctcctt
      901 ccatatggtt tgaaacagcg gctgaaaggc tggatcctga cgcgcgtcaa acggatctaa
      961 agccgcgagc tccttaggca cggtgaatat ttggtggatg gtgcccggct gattcgaaaa
     1021 taaatagatc gtatcgctca tggcgatggc ttcaccgata tcgtgggtga cgagcacggc
     1081 ggttttttga aaatccttta atgttctgaa gacaaggttt tccaaagaaa gcttcgtttg
     1141 aaagtccagc gcggaaaacg gttcatcaag gagcagcagg cccgggtccg gcgcaagagt
     1201 tctggcaagt gccgcccgct gccgcatccc gcctgagagc tctttcgggt atttcttttc
     1261 aacgccgatt aatccgagct taggcagaag gctgagaact tcagctcttt tttcttctgt
     1321 taatgttttt gaaatgtgta aaccgagcag cacgttttcc tcaattgatt tccaaggaaa
     1381 taaataatcc tgctgaagca tataaccgat ttggtgttct ttatggttcg gcacgcttcc
     1441 ttcaatcagc acccggcctt gcgcaggagt aataaggccg gccagaatgg acaggagtgt
     1501 tgtttttccg catccgctcg gtccgagaaa ggagatgaaa tccccttttt caatctgaaa
     1561 atgtatatct ttcacggcgg ttgtcttttc tttcagcgag aaataagtat gtgttacatg
     1621 atccacatgt aaaaaagaca ttcatgttcc tcctattgtt ctgaggtgac ttttttggcg
     1681 atttttgtgt tgacgagttt gctgtacgga atgtgtttcg ggagctctcc ggcttcatcc
     1741 ataatagatt gaagctgttc ccattcatcc ttttgcagaa ctgggtctgc agagaatgac
     1801 ttttgttttt tatatcgctc tattgatgtt tcgataatgg ccggatcggt atcggcaaat
     1861 tccttctgaa tcgtttttgc gatgtctttg gccgggtggc tttccaccca ttgctgggcg
     1921 cgatagatgg cgcgggtgaa tttttccgcc gtcttttcat tggttttcaa ataactttct
     1981 tttgccataa aggttgtgta tggcatttgg ccggaagctt ctccgaagga tgcgacgata
     2041 tggccgatgc cttctttttc aaattgggat gccgtcggtt caaacagctg cacataatca
     2101 cccgttccgg atgcgaatgc gttggaaata ttggcgaaat caatgttttg aacgaggtta
     2161 atgtcttttt tcggctctat gtgattcttt ttcaggacgt actcaccggc catttggggc
     2221 atgccgcctt ttcgctggcc gagaaatgtt tttcctttta aatcgctcca tttgaatgat
     2281 ttctcatcct tccgtgacac gagaaatgtg ccgtccgtct gtgtcagctg cgcgaagttg
     2341 atgaccggat cttttgctcc ctgcgcctcc acgtaaatgg atgtttcaga accgatcagc
     2401 gcgatgtctg acccgtttga caaaagcgat gtcattgttt tgtctccgcc ccatgttgtt
     2461 tgaagtgaca cttggagccc ttctttttta aagaaacctt ttgcttcagc gacatacaga
     2521 ggcgtataga agatggagtg tgtgacttcc gccaccttta cctttgtcag actttcttcc
     2581 tgtctgcaag ccggaagaat gagcaggaaa aaggcgcata tgacaaaaac gcagcccgtt
     2641 ttgagccatt tgttcacggt gtaacctcct tgttttaagc gttaaaataa ccttttctgc
     2701 tttacatatc gtatgatggg tataaaaaat gtgtgagtgc ccatattcac gttgggaaag
     2761 aataaaaaaa ctgatgatat aaggaggcca ttgttttgct ggcagaaaag aaaaggttcc
     2821 cgtctccgag tccgcatatc cgcctctttg aggtatgcta tgagtcagaa gggctgaagg
     2881 taaaggggct tcttgccgag cctgcggcgc cgggaacata tgacggtttt ttatatttgc
     2941 gcggcggcat aaaaaatgtc ggcatggtac gccccggaag aatcgttcaa ttcgcttccc
     3001 aaggttttgt cgtgtttgcg ccctattaca gaggcaacca gggcggcgag ggaaatgaag
     3061 attttgcggg agaggacaga gaggacgcgt tttctgcttt ccgcctgctt cgggagcatc
     3121 cgaacgtcag agaagggcgg gtgcatattt tcggtttttc ccggggcgga atcatggggc
     3181 ttttgaccgc gattgaaatg aggcatcaag cggcttcgct cgtttcatgg ggcggtgtga
     3241 gcgatatggt gcttacttat gaagagcgga aggatatgcg gcggatgatg aagcgggtga
     3301 tcggaggcac gccgaaaaag gtgccggatg aatacagatg gcgttcgccg tttgaaaacg
     3361 cagaccgcat tcaggcccct gtgctgctca tccatggaga gaatgatgag aatgtttcga
     3421 tcgaacacgc ccgaatgatc gaggacaagc tgaaagaggc ggggaaaccg gtggaaactt
     3481 ggtattacag cggttttacg cattattttc cgccgcagga aaacagacgc attgtccggc
     3541 ggctggcgga atggatgaag acacggtaag atgcctgatt tatgatatga taataaagaa
     3601 taagagaatg aaaggggatt ttcattttgg gaatgcctgt tgaatttaat accatgattg
     3661 tgacaaaagg caatgaaaaa cggatagagg aaaatatctt tttattggag aaagagggct
     3721 accgcgtcta tcctcttgat attccgatgg acgtgcgcaa aacgaaaacc ggcgagaaat
     3781 ccggcaccgg cgaggtccaa aagctcgaat gggcgaacgg ccggacaagc attacataca
     3841 gactcacgtc gctccattcg acaaactgaa aaaacaaaag ccaagggcat aaacgccctt
     3901 ggcatttttg attacacgag aggtccgccg gctttggcaa tcgagtccgc atgggaaaac
     3961 tttttaaagt tttctttaaa ctcattggct aaaaacagcg ctttttcgtt gtatgcttgt
     4021 ttatcgctcc atgtgttttc aggctgaaga acttcatccg gaacgcccgg aacatgaacg
     4081 ggactgcgca ggccgaaaat gctgtctgcc gtcatgtcag tctggttcag tctgccttca
     4141 atagcggcct tgaccatcgc tcttgtatac gaaagtttca tccgttctcc gactccgtac
     4201 cctccgccgg tccagcctgt gttgaccagg aagacttgaa cgccgtgttc gtcgatttta
     4261 tgcccgagca tttcggcata tacatgcgcc ggaagcggaa ggaacggtga accgaagcac
     4321 gtcgagaaag tcgtttgcgg agatgtcacg ccgcgctcgg ttcccgcgag tttactggtg
     4381 tacccgctta agaagtgata catcgcctgt tccttcgtca gtttgctgat cggaggaagc
     4441 acgccgaatg cgtccgccgt taaaaagacg atcgcctgcg gatggccggc aatgctcggc
     4501 tgcacgatat tgccgatcat ctcaatcgga tatgcggctc ttgtgttttc cgtgtagaag
     4561 gaattgtcgt aatccgcttc acccgttttt tcatcaagca cgacattctc aagaacagac
     4621 ccgaagcgga tcgcacgaaa aatctgcggt tctttttcct cgctcagatt gatacattta
     4681 gcgtaacatc cgccttcaat gttgaaaacg ccggaatctg accagccgtg ctcgtcatcg
     4741 ccgatcagtt tgcggtccgc atcggctgaa agcgtcgttt tccctgtgcc ggaaaggccg
     4801 aaaaacaggg cgacatcgcc tttttcaccg acattggctg agcagtgcat cggcagtata
     4861 tcctgctgcg gaagcaggaa gttcataatg gagaatattg attttttcat ttctccggcg
     4921 tattcggtgc cgccgattaa aatgacgcgc ttttcgaaag agacaatgat aaatgtttcc
     4981 gaatgcgtgc cgtccgtctc cggatctgct ttaaaatgcg gagctgagag aatggtgaaa
     5041 ggctgcgctt gcgtgtctct ttcattcgtc tccggtctga taaacagctg gcgcgcgaat
     5101 aaattgtgcc acgcaaattc atttacgacc gtaatcggga gtctgtattt ttcatccgct
     5161 cccgcgaatc cgtcaaaaac aaacagttca tcccgctgtt ttaagtagct gacgactttg
     5221 gcgtacagct tttcaaatgc ctcttcagaa atgggctgat tcaccgcgcc ccaatcaatt
     5281 tgattttctg tgctttgttc acggacgata aatttatctt taggtgaccg gcctgtatat
     5341 gcgccggtgg tggcgcgtac ggcgcccgtt gatgtcagcg ttccttcatt tcggctgatc
     5401 actttttcgg taagttttgg agccgataaa ttatgatgca cattcggact tgcaagtaat
     5461 gcttgaagat ctgcggttaa atcaactaat ttcataaaaa ccttcctttg ccggtttatt
     5521 tgtatttcgc tgaatgtgga attagtataa catatatctg aaaatagtct atactatttg
     5581 cggttttttg tttgtgtttt tccattgctt cccgaaataa aggcgcgtaa tcgctttaat
     5641 tcatattgac actttccgcc cttttacgat aagatatttc attgagcgga tactcttatc
     5701 ccgagctggc ggagggacag gcccgatgaa gcccagcaac cggtttctct gtaaaaaagc
     5761 aggtgaaaac actgtgggaa accaaggtgc taacctgatg caaggtttaa tattttcctt
     5821 gagcgataag agtgaaaggc acacagacca aaccctttcc tcgagtggaa aaggtttttt
     5881 tatttcataa aatatgccaa ttaacattct ctgatatagt atgacattgt attaagaggg
     5941 agcgagttcc gtatcatatg aaaaggtctt gcaaaagatc ttttttcagg aggaaaagtg
     6001 aatgagtaaa aaccgtcgac tatttacatc tgaatctgtt actgagggtc atccggacaa
     6061 aatctgtgac caaatttctg acagtatctt agatgagatt ttaaaaaatg acccgaacgc
     6121 gcgcgtggcc tgcgaaacat ctgtaacgac aggacttgtg ctggtaagcg gagagattac
     6181 tacatcaaca tacgttgaca ttccgaaaac agtccgtgaa acgattaaag aaatcggcta
     6241 cacacgcgcc aaatatggat ttgatgcgga gacttgcgct gttttaacat caattgatga
     6301 acagtctgcg gatatcgcaa tgggtgtcga tcaggctctt gaagcgcgtg aaggcacaat
     6361 gagcgatgct gaaatcgaag caatcggagc gggagaccaa ggcctgatgt tcggttatgc
     6421 gtgtaacgaa acgaaagagc ttatgccgct tccgatctct ttggcgcata aattagcccg
     6481 ccgtttgagc gaagtccgca aagaagacat tcttccgtac cttcgccctg acggcaaaac
     6541 gcaagttacc gttgaatatg atgaaaacaa caagccggtc cgcatcgacg cgatcgttat
     6601 ttcaactcag caccacccgg aaattacgct tgagcagatt cagcgcaatc tgaaagagca
     6661 tgtcattaat cctgtcgtgc ctgaggaact gatcgatgaa gagacaaaat acttcatcaa
     6721 tcctacggga cgtttcgtaa tcggcggacc tcaaggtgat gcgggtctga ccggccgtaa
     6781 aatcatcgtt gacacatacg gcggatatgc acgccacggc ggcggcgcat tctccggtaa
     6841 ggatgcgacg aaggtagacc gttctgcggc atacgctgcg agatacgtag cgaaaaacat
     6901 cgtggcagca ggtcttgctg attcttgtga agtgcagctt gcatacgcaa tcggcgtggc
     6961 acagcctgtt tctatttcca tcaatacatt tgatacagga aaagcttctg aagaaaaact
     7021 gatcgaagtc gtacggaata acttcgacct gagacctgcc ggcattatta aaatgcttga
     7081 tctgcgccgc ccgatctata agcagacagc tgcttacggc cacttcggac gtcatgatgt
     7141 ggatcttcct tgggagcgta ctgacaaggc ggatgcgctt cgcaaagaag cactaggaga
     7201 ataattttat agccgcttac ttaagcggct ttcccttttt gtagatgctg ccatgcttat
     7261 tttttacata gcgtgaaacc aatggcgtaa caaagcgtct ataaaaaggg ggtccaatta
     7321 gaaaattaca cttatggagg ctatactatg tgtggatttg tcggtgtttt taataagcat
     7381 ccattaactc aaaccgcaga tcaagaagag ctaatcaaac aaatgaacca aatgatcgtt
     7441 caccgcggtc ctgacagcga tgggtattat catgacgagc acgtcggatt cggcttcaga
     7501 cggctcagta ttattgacgt agaaaacggc ggacagcctt tatcatatga agacgaaaaa
     7561 tattggatca tttttaacgg cgaaatctat aactacattg aattgagaga agagcttgaa
     7621 gcgaaaggct acactttcaa tacagattcc gataccgaag ttctccttgc gacataccgt
     7681 cattataaag aagaagctgc ttcaaagctt cgcggaatgt ttgcgttttt aatctggaac
     7741 aaagctgacc gcgtcatgta cggcgcgaga gacccgttcg gaattaaacc gctgtattac
     7801 acaaccatcg gggacaaagt atattttgca tctgaaagaa aaagtttaat ggccgctcaa
     7861 aacggcattg atcttgatac agcttcttta cagcaatata tgtctttcca attcgttcct
     7921 gaaccgagca cgcttgacgc tgaagtgaaa aaagtcgagc cgggcagcca gtttacgatc
     7981 cgcccggaag gcgacatcgc gtttaaaaca tatttcaaag cgaactttaa gcctgttcag
     8041 tctgatgaag ataaattggt gaaagaagtc agagacgcaa tctttgactc tgtcaaagtt
     8101 cacatgagaa gtgacgttcc tgtcggttcg tttctatccg gcggtatcga ctcttctttt
     8161 atcgtctcag ttgcgaaaga atttcacccg agcctcaaaa cattttccgt cggttttgag
     8221 cagcagggct tcagtgaggt tgacgtagcg aaggaaacgg ctgccgcgct cgggattgaa
     8281 aacatcagca aagtcatttc tcctgaggag tatatgaacg agcttccgaa aatcgtctgg
     8341 cactttgatg acccgcttgc agatccggcg gcgattcctt tgtactttgt cgcgaaagaa
     8401 gcgaaaaaac atgtaacggt cgcgttatcc ggggaaggcg cggacgagct gttcggcggg
     8461 tacaatattt accgcgaacc gctttcgctt aaaccgtttg aacgcattcc gtccggtctg
     8521 aaaaaaatgc ttcttcatgt ggcgtccgtc atgcctgaag gaatgagagg gaaaagcctc
     8581 ttagtccgcg gctgcacacc gcttgaggag cgttatatcg gtaatgcgaa gatttttgaa
     8641 gagcccgtga aaaaacagct gctcaaacat tacaatccag agctttcata ccgtgatgtc
     8701 acgaagccgt actttacgga aagccgttca tacagcgaca ttaataaaat gcagtacgtt
     8761 gacatccata cgtggatgcg cggcgacatc ctgttaaagg ctgacaaaat gacgatggcc
     8821 aactctttgg aactgcgcgt gccgttcctt gataaagtcg tgtttgacgt ggcttctaaa
     8881 attccggatg aactgaaaac gaaaaacggc acgacgaaat accttctgcg caaagctgct
     8941 gaaggggtag tgcctgatca tgtgcttaac cgcaaaaagc tcggcttccc tgtgccgatc
     9001 cgccactggc tgaaaaatga aatgaacgaa tgggttcgca acatcattcg tgaaagtgaa
     9061 acagatgctt atattgaaaa ggattatgtc cttcagcttc tggaagatca ttgtgccgac
     9121 agagcggaca acagccgcaa aatctggacc gtgctgatct ttatgatctg gcacagcatc
     9181 aatgttgaaa aaagactggt gccggaagag ctgaatcatc agccgaaaga agtcattttc
     9241 gtttaatcca aaaggctttc gatgttatcg aaagcctttt ttctattgtt ttttttgtaa
     9301 accgtctatt ccgctctgtt ttcgacaaag tattacgcaa tattcagaaa aaggttataa
     9361 taggactaat cgggtagatt ccggaaagtg ttttctggct atttcgtctc ggtttgttgt
     9421 ttctttgtca aaatcagggg gagggagagt tatgcaaaac aaagaaaaaa cgcttcaccg
     9481 cggcttggaa gagcggcata tctcgcttat gtcgttgggc gccgcgatag gagtcgggct
     9541 gtttctcggg tcggcttctg ccataaagct tgccgggccg gggattttag ccgcttacgc
     9601 ctgcagcggg ctgattatgt tttttattat gcgggcatta ggggaaatgg cgattcaaaa
     9661 gcctgtagcc ggctcattca gccggtatgc cagagattac ctcggtccgc ttgccgggtt
     9721 tttaacaggc tggaattatt ggtttttatg ggttgttacc tgcatggcgg aaatcaccgc
     9781 ggtcggcatt tatatgggct actggttccc tgacgtgccg tcatggatct gggcgctttg
     9841 tgcactcgtc attatgacgg ctgtcaactt tctggcggtc aaagcgtacg gtgagcttga
     9901 attctggttt gcgctcatta aagtcttggc gattctgtca atgatcgcga tcggtctggt
     9961 gatgatcgta ttcggtctcg gaaacggagg cgttgcgctc ggaatcagca atttatggag
    10021 ccacggcggc tttttcccga atgggattaa aggggtgctg ctgtcgcttc aaatggtcat
    10081 gtttgcctat ctcgggattg agctgatcgg tgtcacagcc ggtgaggtca aaaatcctga
    10141 aaaatcactg gcgcgtgcca tagatactgt tttttggcgc attctcattt tttacgtcgg
    10201 agctttgttt gtcattatgt caatttatcc gtggcaggaa atcggttcag gcggaagccc
    10261 gtttgttttg acatttgaaa aaatcggaat acctgctgca gccggaatca ttaattttgt
    10321 cgtattgacg gcggcccttt cttcctgcaa cagcgggatc ttcagcacgg ggcgcatgct
    10381 gttcaatctg gcggaacaaa atgaagcgcc taaagcatac ggtacggtca caaaaggcgg
    10441 tgtgccggga aaagcggtat tggtttcagc gggcgcgtta tgcatcggcg ttttgctgaa
    10501 ctacgtggtg ccggcaaaag tgtttacgtg ggtgacgagc attgcgacgt tcggggcgat
    10561 ttggacatgg tcgattattt tgctttccca aatgaaatac cgtaaaagct tacagccgga
    10621 acaacggaaa aaactgaaat ataaaatgcc tttatatccc ttttcctcat atatctcatt
    10681 ggcatttctc gcttttgtcg ttgtgctgat ggcttttgat gcagagaccc gggtggccgt
    10741 cattatcggt cctgtctggt tcggcatatt attagccgct tattacggga aaggtttcca
    10801 taaaagaaaa gacataggtc tggaaaacgg acagacattc gccgaaaaag cgtaaaaaaa
    10861 gagcccggga catgggctct ttttttcata ggatcgggcc ggcgggggaa gaataaaaca
    10921 aattcctgaa cattttgctt ctgtttcctg acaatcggga gaatgcaaat ggtttttact
    10981 taaataatat tttgaaaaat ggtacagtag taaaacaaag ctgatctatt tttatttctc
    11041 ttgcagtgtt ttatagtatc ggcctttttc aacatattcc gttctgattc tttccatgtc
    11101 ccgtatgtct tcttctgtca gccggcggat aacctttgcg ggccggccga acgcaagaca
    11161 gccgggagga atggttttgc ccggaggaac gagacttccg gcgccgataa acgcgccttc
    11221 tccgatttcc gccccgtcaa gaatgacgga gcccataccg attaaagcat tctttttgat
    11281 gattgcgctg tgcagtgtaa cctgatggcc gatcgtgacg tcatcttcaa taagaagcgg
    11341 gcggttcgga ctttgatgca gacagctcaa gtcttgtatg ctgactcttt ttccgatcct
    11401 tgtcggcgcg acatcccccc ggatgacggc tgagaaccaa atgcttgatt gttctccgat
    11461 cacgacgtcg cccgtaatga cggcgttatc cgcaatgaac gcttcaggat gtatgtcagg
    11521 cgtaaattgt ttataagggt agattatcat gtctcatcct tctttctcta aatttatgta
    11581 agaggtgaac tgcatgtgga cttggaaagc agacaggccc gtcggtacca ttgtcattat
    11641 ccacggggca agcgaatacc acggacgtta taaatggctc gttgaaatgt ggagatcttc
    11701 cggatataac gtggtgatgg gcgatttgcc cggtcaggga acgtcgaccc gcgccagagg
    11761 gcatattcgc tctttccaag aatacattga tgaagtagat atatggattg ataaagcgag
    11821 aacgcttgaa gcgcccgttt tccttttggg ccacagcatg ggcggactga ttgcgataga
    11881 atggtttaag cagcagagaa atccccgcat tacggcactc attttatcat caccttgtct
    11941 gggtctgcaa ataaaagtca ataaagtcct tgattttgcg tctaaaggac tgaacgtcct
    12001 cgctccgtcc ctcagagtgg attccggttt atcacctgat atggcaacga ggaatgcgga
    12061 tatgattgaa gcggatcaaa acgattcttt atatgtcacg aaggtatccg taagatggta
    12121 cagagagctt ttaaaaacca ttgatgccgc tatggtgccg actgatgcgt ttttaaaggt
    12181 gccgcttttg cttatgcagg gcggtgatga caaaatcgtc gataaaatga aggtccgcaa
    12241 atggttttcc ggtgtggctt cccataataa atcgtaccgg gaatgggaag ggctctatca
    12301 tgaaattttt aatgaaccgg aaagagaaac tgtgtttaag gcggcaaaag cctttacaga
    12361 tcagtatatt tgaattcgct gggggtgcat atgttgacag taccggaaca tccttttaac
    12421 cttatggcaa aagtgtatcg ggaaattttt ccgctcgttc atcaggaatt gaacatgtgg
    12481 cgggaaaaat cagattccat taaaaatacc gaactgcggc agcaggcggc cgcaagtatc
    12541 cgcgataagt cgtttcattg tgaaggcggc ggcattttag ccctgctttc gggagagcag
    12601 aaacagaaat gcgtacaatt tatcatcgcg tatcagacaa tcagtgatta tctggacaat
    12661 ctgtgcgacc gcagcacctc gcttgatccc gaggacttcc gcatgcttca tctctccatg
    12721 cgtgacgcgc tgacggtcgg tgccgaggtg cggccgtact atcagtacag agacgagcag
    12781 gatgacggcg gttatcttca tgagctggtc agaacatgcc agcgggtgct cgggtcaata
    12841 gaacattacg gtatcattaa accttatttg cttgagctgt gtgattatta ttgcgacctt
    12901 caggttcata agcatgtcgt tgagcatgaa cgcgttccga ggcttaaagg ctggtttgag
    12961 cagtaccggt cacagcttcc ggaaatggag tggtttgagt tctcggcctg cgccggatcg
    13021 acgttaggca ttttctgtct cgttgcttac tcattccagc ctgattttaa cgaacatacc
    13081 gctgagaaaa tccgcagcag ttattttccg tacatacaag ggctgcatat actgcttgat
    13141 tatttaattg accaggaaga ggatctgctt gaaggcgatc tgaatttctg tacgtattat
    13201 cagtctcatg aagaaatgat gcagagactg cagcatttta ttgaaaaagc ggatgaacat
    13261 ttgcaaggca ttccgcatga aaattttcac cggctgatca acagagggct gctcggcgtc
    13321 tatttatccg atgacaaagt cgccggccaa aaagaaatgg gccgcctcgc gcgaaagctg
    13381 atcagggcta gcggaaaaac gtcatttttc ttttatatca acggaagagc ctaccgcaaa
    13441 tttcagaaga tggcttggac gaaaagttcg taatgggtga actgcgcctc tcgtgtaaat
    13501 catgacggcg cagtttttta tttatgacgt gaagtatgaa atgaaacatt gtttgcgcct
    13561 gcagaatatg atactttaat tttatgaaaa aattaaagta tttagcggtc atagcattac
    13621 tttccatttc cggaggctgc tccgtcatcc atgcttccgc cggctatcat cctgtcttga
    13681 tagcgcacag gggctcttct gcgattgagc cggaacatac agctttgtct tatgcgcgtg
    13741 ccattaaaga caaagcagat tatattgaga tagacttacg gaagacgaag gacggccatc
    13801 tgattgcaat tcacgataaa acggtagatc ggacaacaga tggtaaaggg atgacagatg
    13861 atctgtcttt ggctcagatt aagaaactga atgcgggaaa aggagaaaag attttaacat
    13921 tagaagaaat catacagaaa ttcggacaaa ctgccaatta ctatattgag acaagagaaa
    13981 gcaacggcag cctggtgatg gaaaagaaac tgattgacat attacaaaaa cataagctga
    14041 tttccagcca taaagcagtc attgagtctt ttagcgggaa gagcttaaaa aaagttcgat
    14101 ctatggataa aaaagttcct cttgttcgat tattaaaaga taacgaggct gaggagataa
    14161 atgataagca gctgcaaacc atcagaacgt atgctgatac agtcgggctc aacgccaaat
    14221 tggcaaatga agcagtcgtg aagtgcattc atcacaataa gatgaaagtg cacgtgtttt
    14281 ttgataagga agacgagcat acgctgacgc ctattatgct gaaacaaaaa gcagatggtg
    14341 tctttacaaa caatcccgct tatacacgcg gcgtgctgca aaacagtaaa taaaaagaga
    14401 catgcgcatt ttacgctgtc tcttttttta acggtttctt ttttgccgca aggtgcattg
    14461 cgaatttgcc gatcagcccg atgacaaaaa atgcagcaaa ccaccagtaa taggtttttg
    14521 cgaactcaaa tcctaaatgt cttgataaaa tgatgacgaa catcacatag ggaacacttg
    14581 aaaatatgat gcgaagaata ttcaaactgc cgctcctccc agatgttaca cttaaaagat
    14641 gaactttttt ccattatttc atagtaattg atttttcaga aaaagtaaac acaaaaagaa
    14701 tcggcccgct tatgtcaggc cgattcttta tttgccggca gatttctttt caatcgctat
    14761 aataaacggc gggtcgtttc gctggttgag aaagccgtag ctcagcacgc gcgctttttc
    14821 ctgatcaaga ttgctgcagt actccagtaa tgcacttttt tccgtcttgc cttcaggatg
    14881 cccgtggtac acaacgagaa cgatcatccc gttctccttc agcagttcaa ggagctgttc
    14941 gatcgcggaa atggttgagt ggccgtttgt cgtaatgctt ttatcgccgc cgggcagata
    15001 gccgagatta aacacggcgc aagccacacg accgtgcgca tcctcaggca gcgatgcctt
    15061 tatttgatca tggctcttat ggtgaagcgt gacgcgcgga ctgaagtcgg caccgagccg
    15121 ctccttcgtt ttagcgagtg cgtccgcttg aatatcaaag gcatggacat gtcctgtctc
    15181 accgacaagg ccggccagga aatatgtatc atgtccgttg cccatcgtcg cgtcaaccgt
    15241 gatatcacct tcctgtgcgg cggacttcag caattcttta ctgaaaggga ggatgtgcat
    15301 caaggtcata gggcggtctc ctccccgatc tttctgaaga gctttccttg atagcttccc
    15361 cgtgtttcca gctctttttg aatggcgccc agtacttccc acttattgac gctccacatc
    15421 ggtccgacca ttaattcgat cggcccgtct cccgtaatgc ggtgaacgat catttccggg
    15481 ggaatgattt cgagctgatc acatacaaga cttacatatt cttcttgaga aaggaactcc
    15541 agctttcctt tttcatattg cttcaccatc ggtgtgcctt ttaataagtg aagcaggtga
    15601 attttaatgc cttgcacatc caaatcagcg acggctttgg ccgtctccat catcatgtcc
    15661 ctgttttcaa gcggaagccc gttaatgata tgggaacaaa cgcggatgcc gtgttttctc
    15721 agtttattga caccctcaac atagcagtca aaatcatggg cgcggttgat cagaagggcg
    15781 gtccgctcat gcacggtctg cagcccgagt tcaacccaca aataggtccg ctcattcagt
    15841 tcggccaaat attccacgac atcgtccggc aggcagtccg gacgggtcgc gatcgacatg
    15901 ccgacaacgc cgtcaagctt gaggacggat tcgaattttt ctcgcagctc ctctaccgga
    15961 gcatgcgtat tcgtgaacgc ttggaaatat gcgatatatt tgccgtcttt ccacttttcg
    16021 tgcatgcggt ttttgatatc gtgaaattgc gtgagtaagt catcggcccg attgccggca
    16081 aaatcgccgg agcccgccgc gctgcagaat gtgcagcctc cgtgtgcaac cgtgccgtcc
    16141 cgattcgggc agtcaaaacc gccgtcaagc gcgactttaa acactttatg cccgaaatgc
    16201 tcccgcagat gataatttaa tgtatggtac cgtttttccg tatttgaata aggaaaaggg
    16261 ttattctcgt tcaatgttca aaaagcctcc ctcacatcag atgcatccta aaattgtagc
    16321 atgaatgatg gagcggaaca atgaaacaat tatggaacgg tcaggacgta atatctacct
    16381 ggtttttctg ttgttgtttt aaacgttttg gagaaatatc actgaacaat gcaaaaataa
    16441 ttcctaaaat aagaattaca ctgcctactt tgaatgtatt attaaaactg tcacttattt
    16501 tttcattata taaatttgaa atttttttct ggatagccat aacttccttc ttttgaatat
    16561 tgaagctttt ttgtactttt tctttatacg gatccggggt tatagagaga atttcttcct
    16621 cttttttgtt taattcagca atacttttgc ttcgatcgaa acctttactg tctgaatgct
    16681 ttaagtgagt tattatctcg ttctttgcat ttttatcaaa aacctgattg ctttccacaa
    16741 ttttaatggc ttcttttttc gcagtagctg tgtgatcatt tatattcatt gtaagcacag
    16801 atgtaagtat ggcaattcct agcgcttgtc caactgtccg catcatatta agaatacctg
    16861 aggcaattcc tactttctca ggaggaataa gccgtatccc tgaactcatt gctggtccta
    16921 ttacaagccc taaagctaag ccggtcaaac ataacagaat aattactgac gttatagaac
    16981 tgtcgtatcg tatgtatcca tataaatatg ttgtgattgt taaaccgagc atacctagac
    17041 ccgaaagcca aatgcccccg agtttatcag atagctttcc agaaagtaca gaggtaaaca
    17101 tagatgatag agctaatgta gaaacaatta accccgcttc taattcagtt tttcccatta
    17161 aattagtgag gagtaaagta ataataaggg taccgcttgt taatccaagg ccctgcataa
    17221 agagggtgaa agaactgaaa ctaaacgtac gtatcttcag catggataag ggaatcatcg
    17281 ggtttttaat tttagattca ataaagaaaa acaaacagaa taataataca gagattacaa
    17341 aaagagagat aattaatggt gatgaccagc ctaagtcaga tacttttgca aaaccaaagg
    17401 ttaaacagaa gagagctccg gataaaataa gaatccccat gtaatcaatt tttttactca
    17461 ctgtttcatc ataactctca gtaataaaaa atgctgctaa aaaaagagaa atcagaccta
    17521 aaggaatatt tatgaagaag atagcttgcc aattaaaatt ttcagttaat aatcctccaa
    17581 gtacaggtcc taatgtagct gctaatcctg agaaagcacc ccagattcca atgatcattc
    17641 cttttttatt ttgaggtacg atagctaaag ctataggcat tgtaacaggt acaatgaaag
    17701 cagcagataa tccctgaatc actctaattg tgacaagcat ttcaattgaa gtgctcaaac
    17761 atgcaataac tgatgtcaaa ataaaaagtg ctaatccaaa cataaaagct ttttttcttc
    17821 caaaatggtc tgccagcttt gatgcaccta ctaataaaac cgcaaaagct aaagtataac
    17881 ctgtagccac ccatgctact tgagaaaggt tactcgaaaa ataatccagc atcttaggta
    17941 aggcgatatt tactatagtg gtgtccatta ctgaaatgaa tgtacctaat aataatgcag
    18001 ataacatgat tatttttttg aaattcaata tacttacatc tccttttaga aaactatcta
    18061 attaaaactt tgacgtatgt ctaaaaacat aataagaaaa aaaatcattt gtgtcaatat
    18121 tattcataat atgtttatta gacccaatat attataaaat aacaaatgta ttaagataac
    18181 cattacttta aatctattaa aattccaaat taatacttta caaatagaca ataattcctt
    18241 attattattt aaaagttggt ttttcatggt tttttttgaa aaaggaggag ctaatgaccc
    18301 atccaattaa acttttttgc attccgcatg ctggaggatt gtcaagtatt tatagtgaat
    18361 ggagtaactc agttggacca gaaattgaac taatacctgt tgaactagca ggaagaggct
    18421 ctagattttc tgaaaatccc tacaaaacaa taaatcaggc tatagatgat attacagaat
    18481 taatattaag aaaatgtgat aataagtgct atgcgattta cggccatagt atgggtgcat
    18541 atatatcgta tgaagtaata cttaaattaa tgaaggttac agataatctt cctcagcatt
    18601 tatttgtatc tggaaaaggc gcaccttatt taactaagga aacatttata agcggtcttc
    18661 ctgataaaca agttattcaa tggttaaaca aattaggggg aattcccaag gaacttatcg
    18721 agaattacga actaatgaaa ctatttcttc cagtaataag gaatgattat aaactaatag
    18781 aaagttacaa ccacaacatc aaaaaaaaat tatcaaatgt tacgttaact gttttaacgg
    18841 gcaagtttga cgaatcaata actataggag aagttgaagg gtggaaagaa tattcagcaa
    18901 aggaggttga tgtataccag attagcggag ggcatttttt tattaatgaa tccgttacag
    18961 aagttatatc aattattaaa gataaattat tggtttaagt ttagtatgga ggtttttaac
    19021 gtgaaaaaat acttttgggc tcctcatgtt cactggagaa atgaaaataa ccatattatt
    19081 attaatgatt ttcaatttag agggaaagta gttgaacttt ttcctgatat ttattttcat
    19141 tttcaaaaag gcatttcttt aagcgaaata tatgttattt ttaaagactt taatccaaag
    19201 attttaaaaa tgtttctaaa agatttaata cgtaatagag ttttagtttg caatgtaagc
    19261 acaccgacag agcttttcga aacgcaaaac aaatttgttt atcaagaata tgacgatgag
    19321 ttttttttat acaaagaaaa tatagaatct tataagaaga aacaattaac taggtttatg
    19381 tcaaagaata ctcttcaatc aattgatttg gaggaatgct cagatttgcc ctctttagtt
    19441 caaaatagaa aaagtactag gaattttgat actagtaaaa tgatgaattt ttctaagttt
    19501 agtcggttgt taaatgtctt taaacagtct ccaattcaag agggtattaa atatttctac
    19561 ccaagtgcag gaggactgta tcctgtcaac atatatttgt atattaaaga tgggagagtc
    19621 gaaaatcttg aggaagggat atatttttat aatcctcaca gccactctat caatttactt
    19681 aatagagtaa aactggctga aaaaaaatat cattatttta taaaccacag tgcatttaat
    19741 acttcgaatt tctctatctt tttcaccctt gattgtgatg taatcatgcc caaatataag
    19801 ggtgcggggt attactatgg tattcttgaa tgtggtgtta tgtcagctac attggctaat
    19861 atagcagaat attttgatgt tggatcgtgc tccataggag aaatagactt cgataaaatt
    19921 aaagatgaat ttaatttgaa tagcaatgaa atctatttac attcggtaga ggtaggacta
    19981 aagaataagg aggtaaatca ttgattaata acacgctagt aacgagtaat aaatttaaag
    20041 agatttctaa ctttataata aaaaaaattc gtgaattaag taaagatgat tcagttgatt
    20101 taagaactaa tatttttgat tatcaaatat cttctattaa tatattaaaa ttacttggag
    20161 ccattgaaga tacatataat ataaatattg aattttatga ttatattgac aacccagatg
    20221 tactgtcatt ttgtcaagtt gtttatgaaa agtttcagtt attagataat aaaaaagagt
    20281 ataatatatt acatttatta agcgatgaag aaaatgccta taaagaattt gatcttacaa
    20341 atgttcaagt tgcttattta tctggaagag acaagcaatt tgaactgggg ggaacttcca
    20401 cccatgcttt tgtagaattt gaggctgaac tagatattga aaaattcaat aaaagtgtac
    20461 aagctgtgat agagcgtcaa cacatgctac gtgcagtttt tttatcaaat ggtaagcaaa
    20521 aaatacttga acacgtaccg aattataaat tagctattca agatgtgagt tatcttaaaa
    20581 aatcagacca agaagacaaa atattagaag caagaaaagt aactaacgaa cgaatcttcg
    20641 atccatacca atggccattg tttgaattta aagctttaaa aatcagtgat aaactatata
    20701 gaatattctt tgatatcgat atgttaatag cagatggagc tagtatccag cttttattta
    20761 aagagatatc tgaattgtac aatggaaaga ttcaagagcc tttagaagta tcctatagag
    20821 attatatgtt agcttataac aaattaaagg gaaatcataa atatcaggat gacaaggaat
    20881 attggttaaa taaacttaaa agttttcctt caacaccagc tctgccagta aaagtagatt
    20941 tagcatgtat aaaaaaacct acttttaaaa gaaagaaaaa aattattgag aaaagaaatt
    21001 ggaatcaatt tgtgaattta tgctctcgga agaatattag gcctagtata ctacttttgt
    21061 ctatttattc aaaagtgttg tctaaatgga gtaatcagca aaatattgcg ttaaacacta
    21121 cattatttaa aagaagacct ttgcataagc agattaataa cgttataggc gattttacag
    21181 aaattatgat atttgatgta tgcttcaata atttaaatca tttttgggaa gaagtaaaaa
    21241 atattcagga taacttcttt aaatgcttat cacataatga ttttgatgga atagagttta
    21301 ccagagaata ctgtgaattt aatgatatag atagaaggaa agctgttttt ccgattgttt
    21361 ttacaagtat gttatttgaa aatgaattaa actatttaga ttctctagga gtttttatag
    21421 agagtatcag ccagacatca caagtttatc tggatcatca agtgatagag ctcaatgatg
    21481 gagtcatgct tagttgggac tatgtttcag aggcttttga aaatgatgta attgagtcaa
    21541 tgtttgagga gtatacccac attattgacc aattaacgtc cggtgagatg atgtcttctg
    21601 aagatacagc actggaacaa gcaattactg attataatca aactgagaag gccatcaagc
    21661 cggatacttt atatcacttg tttgcgagac aaacaataaa aacacctgag aatattgcga
    21721 ttgagtgtca aggaagagca gttacctatc aagagttaca agtcatgtcc aaccgcatat
    21781 ctagtttttt ggaagagaag ggaattcagc caaatgagta tgttggggtt attgttgatc
    21841 gtgagatcga gacaatcgcc agtatcctcg cagtgttaaa aattggagct gcctatatcc
    21901 caattaatcc ggaatttcca aaagaaaggc aatcatatat tctgaaagat ggtgattgta
    21961 aagttgtatt aacagctgaa ctggcaaaaa ctattgtgtc aagctataaa gagtctaaaa
    22021 gagaaagtgt ggcagtgccg gaacaaatag cttatgcgat atacacttca ggaagtacgg
    22081 gaaaacctaa aggtgtaatt ataaagaatg aggctgtaac taatactata ttagacatca
    22141 atgaaaaata cagtgtgaat gaaacagacc ggtttatcgg attatcatct atgtcctttg
    22201 atttatcaat atatgatatt tttggtgctt tttctgcagg agcaacatta gtaatgatcg
    22261 aagatcagag agatattaaa aagattcatg acatcgtaaa agaggaaaaa attacagtct
    22321 ggaactccgt tcccatgatc atggaaatgt tagtaaacta tatggatgaa acagaaaaca
    22381 aatctaacgc tggagttatt aactatgacg agcttcctga attaagactg gtattattaa
    22441 gcggggattg gatacctgtt catcttcctg agaggattaa ggatcacttc gttgaaagtg
    22501 aagtcataag cttaggcggg gctactgaag cgtctatttg gtcgatttat tatccaatta
    22561 aaacagtcaa ggctgaatgg accagcattc cttacggtta tccattatca aatcaaactt
    22621 actatgtttt aaactatgaa aatgatcctt gtccaatcgg agtgaaaggt gaactttaca
    22681 tagggggaaa aggtgtagca gacggctatt taaatgataa agaaaaaact gaagcgtcat
    22741 ttattgatca cccagatttc ggaagaattt atcgtacggg ggatatgggg gtcttgacgc
    22801 aagagggtta tattgagttt ttgggacgga aagatcatca gattaaagtt cgtggatatc
    22861 gcgtggagtt aggtgaaata gaaagtgtaa tattagagca ccgacaggtg agaaatgcgg
    22921 tagtcattaa tcaaaaggat gccagaaatc aagatgtgtt atatgcgtac gtaacggggc
    22981 accaatcctt accgccaact gatctgaaag agtttttaag cctgaaagtg ccggaatata
    23041 tgatacctag ctatatcgta cagattgaag aggttccttt aacaagtaac ggaaaagttg
    23101 atcgtaaaaa actactggct ctagacgtta cagatcaagc atcgattgga aggaaaatca
    23161 aagagcctcg aacagaaatt gagagagatt tagttggtat ctggaaaagc gttctgaaaa
    23221 caaatgaaat cagcatagat gacaactttt ttgaattagg cggcaattcc atattgatca
    23281 ttaatttaat tactgctatt gaggatcgtt tatttattaa attagatttt aaaaatttta
    23341 tatccaacag taccattgag aaactagcaa aagttatcag tgtctctgaa agaaaaagta
    23401 aaacaaatag taatgtgatg gaaattcaag ctgatatcaa gcataaaaat acggaattcg
    23461 atttaactaa cgttcaaatg gcttatctaa tgggaagaga taaacaattt gaacttggtg
    23521 gcacctcaac gcatgcttat ttagaaattg agactgagct gaatattgaa aaactcaaca
    23581 aaagtttaca aaaagtaata gatcatcaag acatgctgcg cgcggtcatt cttccgaatg
    23641 gaaggcaaaa gattcttcaa caagttcctc agtatgaaat atctgtacag gatattagtc
    23701 aattaagtga tatagaacaa gagaagaaaa ttgcagaaga aagagacaga acatcacatc
    23761 atatctttaa tccaaatgag tggcctttat ttgaattcaa agccttgaaa attcaagggg
    23821 ataaacatag attatttttc gacatcgata tgttaatagc tgatggagcc agcatccagc
    23881 ttttatttaa acagatatct gaattgtata atggaaaaga tgaaatggta ccattggaaa
    23941 taagctatag agattatatg ttagcatacc aaaaagtcaa gaccactcaa aaatatgaaa
    24001 atgataaagc ctattggtta agtcagctcg aagattttcc aaaagcacct gcggtgccat
    24061 taaaagaaag attagatgca ataagcaagc caactttcaa aagaaaatct aaaataattg
    24121 acaagcttct atgggaaaca ctttgtaaaa aagctgcaag ctataatatt acacctgcaa
    24181 taatattatt tacagcttac gcaaaagtgt tgtcgaagtg gagtaaccaa caaaacttag
    24241 cggtaaatac aacagtattt aatagacagc ctctccataa acaagttaat gatataatag
    24301 gtgattttac atcgctgatt atgttaaaag cgagttttga gaaaaaaatg aacttttggg
    24361 aggaggcaaa aaaggttcag gttactttca tggaagcgct tgaacataga gactatgatg
    24421 gagttgaatt tataagagaa tatgctagat ataataattt aaagcacaaa agtgcgacaa
    24481 tgccagtagt gttcaccagt atgttatttg gaaacatgtt taatcttaat aataatgatc
    24541 tattgaatat tggtgagtta aaaatggcag tcagccagac atcacaagtt tatctggatc
    24601 atcaagtgat agagctcaat gatggagtca tgcttagttg ggactatgtt tcagaggctt
    24661 ttgaaaatga tgtaattgag tcaatgtttg aggagtatac ccacattatt gaccaattaa
    24721 cgtccggtga gatgatgtct tctgaagata cagcactgga acaagcaatt actgattata
    24781 atcaaactga gaaggccatc aagccggata ctttatatca ct
//
