LOCUS       NZ_PVRO01000017        22575 bp    DNA     linear   CON 28-NOV-2024
DEFINITION  Bacillus velezensis strain DJFZ40 NODE_19_length_22575_cov_26.0625,
            whole genome shotgun sequence.
ACCESSION   NZ_PVRO01000017
VERSION     NZ_PVRO01000017.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus velezensis
  ORGANISM  Bacillus velezensis
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus; Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 22575)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Genotypic and phenotypic analysis of antagonistic Bacillus spp.
            isolated from rhizosphere soil of plants in Tibet
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 22575)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) UG, NordReet, Marienstr. 27a, Greifswald
            17489, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. A5-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 35.83x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002998885.1-RS_2024_11_28
            Annotation Date                   :: 11/28/2024 01:53:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,731
            CDSs (total)                      :: 3,632
            Genes (coding)                    :: 3,538
            CDSs (with protein)               :: 3,538
            Genes (RNA)                       :: 99
            rRNAs                             :: 8, 6, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 1 (5S, 23S)
            partial rRNAs                     :: 6, 1 (16S, 23S)
            tRNAs                             :: 78
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 94
            CDSs (without protein)            :: 94
            Pseudo Genes (ambiguous residues) :: 0 of 94
            Pseudo Genes (frameshifted)       :: 48 of 94
            Pseudo Genes (incomplete)         :: 50 of 94
            Pseudo Genes (internal stop)      :: 12 of 94
            Pseudo Genes (multiple problems)  :: 13 of 94
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:53:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 22575
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVRO01000017.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            complement(<1..6118)
                     /locus_tag="C6354_RS18250"
                     /old_locus_tag="C6354_18240"
     CDS             complement(<1..6118)
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 3.9e-19.
                     Score: 59.6. Matches aSDomain:
                     nrpspksdomains_C6354_RS18250_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-303). E-value:
                     1.3e-113. Score: 371.0. Matches aSDomain:
                     nrpspksdomains_C6354_RS18250_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (469-866). E-value:
                     3.3e-105. Score: 343.9. Matches aSDomain:
                     nrpspksdomains_C6354_RS18250_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (972-1041). E-value: 4.7e-25. Score:
                     79.6. Matches aSDomain: nrpspksdomains_C6354_RS18250_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1055-1334). E-value:
                     1.8e-103. Score: 337.6. Matches aSDomain:
                     nrpspksdomains_C6354_RS18250_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1500-1901). E-value:
                     4.3e-110. Score: 360.0. Matches aSDomain:
                     nrpspksdomains_C6354_RS18250_AMP-binding.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014305115.1"
                     /locus_tag="C6354_RS18250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18240"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_142395333.1"
                     /sec_met_domain="PP-binding (E-value: 1e-17, bitscore:
                     54.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.2e-91, bitscore:
                     296.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.4e-122, bitscore:
                     397.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKKNAIQDIYPLSYMQEGMLFHSLLQKESQAYAEQASFSITGKV
                     DTRVFEESVHALFERHDIFRTIFISQNVSVPQQVVLKERNVSIIEENLTNLNKADQIKY
                     IEEAKRRDREKGFHLQKDMLMRVTLLQTGECEYTCIWSFHHIIMDGWCLGIVLKEFFQI
                     YASRLRRTPLTLEPAVPYGTYIKWLMEQDKEKAASYWERYLEGFEQQTVLPKQKKSGES
                     RQEEVTFSFSKEDTAKLKELAVKEEVTLSTIFHTLWGILLQAYNQTEDAVFGSVISGRP
                     SEIEGIERMIGLFINTVPVRISGANIPFQKLIKNVQKDALKGQAYSYHPLYDIQANSQV
                     KQGLIDHILVFENYPVEQELDVLNSKGDTKDLFHIHDFSMEDETNYSFYLMVAPGDEIH
                     LKMRYDSSVYDRQFIENIKGHLTHIVSQILDKPDITPDKLVIITPEEKEQLLAPISEET
                     EMPEYDTIHAMFERQAAQTPDQIAIRYEGGSVTYKELNESANKLARLLQKRGLKREEPV
                     GVMLGRSPSLAAAVLGILKAGGAFVPIDPGSPKERIRYVIENSGCVHVVTERHQSLPAE
                     QTLQVTYIEEAGTEADGSNVQSINTADDLLYMIYTSGTTGKPKGVLLEHKNMANLLSDQ
                     LTNTDIDFCTNVLQYASLAFDVCYQELFSVLLSGGTLCIVPESIKRDVSQLYSFIDQHK
                     TEVVFFPTAFVKMLFNEEGYAQSFPRCVKHVITAGEQLTISRLFRQTLRLHGMHLHNHY
                     GPSETHVVSTYTISAGDDIPEHPPIGKPIHHNKMYILSKNRQLQPLGIAGELYISGANT
                     GRGYVNNPALTEEKFLPDPFRKGAVMYRTGDLARLRADGQIEYIGRTDDQVKIRGYRIE
                     PKEIETVLANHHAAKEAAVLIQTNESGENELCAYCSVSQATDPSQLRSDLAKELPDYMI
                     PVKWAFVDAIPLTGNGKVDQRALPEASAYAAGRRYTAPRNVTELKLTRIWEEVLQTGPI
                     GVHDHFFELGGHSLKATALVAKIAKECSVQIPLSDVFSYPTVEELAKIIGEAEENPFAS
                     IEKTETKETYPVSSAQKRMYVLHQLENGGVSYNIPAVLEVKGPFDRDRMEAVFKELIRR
                     HEPLRTSFEEKNGRPVQRIHDEVPFAFTKEQSAEAFIRPFDLGKAPLFRAGFVQIEKDR
                     HLLLADMHHIISDGVSVNLLIREFSELYAERSLPPLRIQYKDYAVWQQSFKAGAAYRKQ
                     EEYWLNRLAGEIPVLELPADKPRPPVRSFSGDRVSFVISEKHTAQLKKLAKENKCTLYM
                     TLLGVYTVLLARLSGQEDMIVGSPIAGRPHADLDAVLGMFVNTLAFRTRPDGSMTFKEY
                     LKEIRQTALEAYEHQDYPLEELVDKLGVPRDMSRNPLFDTTFALQNMEQQKLRAAGLEL
                     QPADVSLPISKFDLSLYISENAGELYCQFEYSTDLFERKTIQKWAEFFTTLAENAAADP
                     SLELDDISVLSEKEEVSLLQEFSPLQKTAFPLHQPLHDLLEQQAEKTPDRPAILTDDIS
                     ITYQELNERANELAHRLIKRGIRLEDKTAIMGRRSPDMLIGIYAVLKAGGAYLPIDPDY
                     PEERIRFLLKDSGVKFLLAEPELFAPDLFEGETISLKSGQTGNPEAAANPNVPVKPDSL
                     AYIIYTSGSTGRPKGVQVEHQSAVNFLYSLQTRYGLKDSDTILHKTSYSFDASIWELFW
                     WPIAGASVFLLPQGGEKDPEMILNALEKNRITAAHFVPSMLHAFLEYINSRKQPIKKTC
                     LKRVFAGGEQLGPHLVSRFYDLLPGTELTNSYGPTEATVEAAYFDLPQGKEFHNVPIGS
                     SGHNMRLYILNQKKQLLPPGCIGELYIAGTGVARGYLNRPELTEERFVDDPFYPGERMY
                     QTGDIARWTEDGLVEWLGRSDGQVKVRGYRIEPGEIEAAIRRIDGIREAAVTARTEHGE
                     TALYAYIEGRKSDDVRAELATRLPAYMMPAQFIEMSEWPVTPSGKLDRRALPAPGGAAD
                     RQVYTAPRNVTEMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATAL"
     source          1..22575
                     /altitude="4000 m"
                     /collection_date="2005"
                     /db_xref="taxon:492670"
                     /geo_loc_name="China: Tibet"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Bacillus velezensis"
                     /strain="DJFZ40"
                     /submitter_seqid="NODE_19_length_22575_cov_26.0625"
     region          1..22575
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..22575
                     /SMILES="NC([*])C(=O)N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22575
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:>22571](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..>22571)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS_motif       complement(164..190)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0024"
                     /evalue="1.60E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1985"
                     /protein_start="1976"
                     /score="5.1"
                     /tool="antismash"
                     /translation="GKLDRRALP"
     CDS_motif       complement(386..451)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0023"
                     /evalue="3.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1911"
                     /protein_start="1889"
                     /score="35.2"
                     /tool="antismash"
                     /translation="WLGRSDGQVKVRGYRIEPGEIE"
     aSDomain        complement(416..1618)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6354_RS18250_AMP-binding.2"
                     /evalue="4.30E-110"
                     /label="C6354_RS18250_AMP-binding.2"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1901"
                     /protein_start="1500"
                     /score="360.0"
                     /specificity="substrate consensus: Gln"
                     /tool="antismash"
                     /translation="LEQQAEKTPDRPAILTDDISITYQELNERANELAHRLIKRGIRLE
                     DKTAIMGRRSPDMLIGIYAVLKAGGAYLPIDPDYPEERIRFLLKDSGVKFLLAEPELFA
                     PDLFEGETISLKSGQTGNPEAAANPNVPVKPDSLAYIIYTSGSTGRPKGVQVEHQSAVN
                     FLYSLQTRYGLKDSDTILHKTSYSFDASIWELFWWPIAGASVFLLPQGGEKDPEMILNA
                     LEKNRITAAHFVPSMLHAFLEYINSRKQPIKKTCLKRVFAGGEQLGPHLVSRFYDLLPG
                     TELTNSYGPTEATVEAAYFDLPQGKEFHNVPIGSSGHNMRLYILNQKKQLLPPGCIGEL
                     YIAGTGVARGYLNRPELTEERFVDDPFYPGERMYQTGDIARWTEDGLVEWLGRSDGQVK
                     VR"
     aSModule        complement(416..2953)
                     /domains="nrpspksdomains_C6354_RS18250_Condensation_LCL.1"
                     /domains="nrpspksdomains_C6354_RS18250_AMP-binding.2"
                     /incomplete
                     /locus_tags="C6354_RS18250"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(533..622)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0022"
                     /evalue="2.60E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1862"
                     /protein_start="1832"
                     /score="58.1"
                     /tool="antismash"
                     /translation="PPGCIGELYIAGTGVARGYLNRPELTEERF"
     CDS_motif       complement(731..760)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0021"
                     /evalue="4.40E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1796"
                     /protein_start="1786"
                     /score="6.9"
                     /tool="antismash"
                     /translation="SYGPTEATVE"
     CDS_motif       complement(1145..1204)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0020"
                     /evalue="1.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1658"
                     /protein_start="1638"
                     /score="32.7"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGRPKGVQVEH"
     CDS_motif       complement(1241..1273)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0019"
                     /evalue="2.20E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1626"
                     /protein_start="1615"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="KSGQTGNPEAA"
     CDS_motif       complement(1391..1429)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0018"
                     /evalue="5.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1576"
                     /protein_start="1563"
                     /score="16.4"
                     /tool="antismash"
                     /translation="AVLKAGGAYLPID"
     CDS_motif       complement(1958..2077)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0017"
                     /evalue="5.00E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1387"
                     /protein_start="1347"
                     /score="67.1"
                     /tool="antismash"
                     /translation="RQTALEAYEHQDYPLEELVDKLGVPRDMSRNPLFDTTFAL"
     aSDomain        complement(2117..2953)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6354_RS18250_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.80E-103"
                     /label="C6354_RS18250_Condensation_LCL.1"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1334"
                     /protein_start="1055"
                     /score="337.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="ETYPVSSAQKRMYVLHQLENGGVSYNIPAVLEVKGPFDRDRMEAV
                     FKELIRRHEPLRTSFEEKNGRPVQRIHDEVPFAFTKEQSAEAFIRPFDLGKAPLFRAGF
                     VQIEKDRHLLLADMHHIISDGVSVNLLIREFSELYAERSLPPLRIQYKDYAVWQQSFKA
                     GAAYRKQEEYWLNRLAGEIPVLELPADKPRPPVRSFSGDRVSFVISEKHTAQLKKLAKE
                     NKCTLYMTLLGVYTVLLARLSGQEDMIVGSPIAGRPHADLDAVLGMFVNTLAFRTRP"
     CDS_motif       complement(2126..2215)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0016"
                     /evalue="3.90E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1331"
                     /protein_start="1301"
                     /score="41.7"
                     /tool="antismash"
                     /translation="DMIVGSPIAGRPHADLDAVLGMFVNTLAFR"
     CDS_motif       complement(2474..2506)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0015"
                     /evalue="4.10E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1215"
                     /protein_start="1204"
                     /score="13.0"
                     /tool="antismash"
                     /translation="QYKDYAVWQQS"
     CDS_motif       complement(2537..2602)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0014"
                     /evalue="8.00E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1194"
                     /protein_start="1172"
                     /score="31.2"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNLLIREFSELY"
     CDS_motif       complement(2774..2884)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0013"
                     /evalue="1.00E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1115"
                     /protein_start="1078"
                     /score="50.1"
                     /tool="antismash"
                     /translation="SYNIPAVLEVKGPFDRDRMEAVFKELIRRHEPLRTSF"
     aSDomain        complement(2996..3202)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6354_RS18250_PCP.1"
                     /evalue="4.70E-25"
                     /label="C6354_RS18250_PCP.1"
                     /locus_tag="C6354_RS18250"
                     /protein_end="1041"
                     /protein_start="972"
                     /score="79.6"
                     /tool="antismash"
                     /translation="ELKLTRIWEEVLQTGPIGVHDHFFELGGHSLKATALVAKIAKECS
                     VQIPLSDVFSYPTVEELAKIIGEA"
     aSModule        complement(2996..6097)
                     /complete
                     /domains="nrpspksdomains_C6354_RS18250_Condensation_DCL.1"
                     /domains="nrpspksdomains_C6354_RS18250_AMP-binding.1"
                     /domains="nrpspksdomains_C6354_RS18250_PCP.1"
                     /locus_tags="C6354_RS18250"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3257..3283)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0012"
                     /evalue="1.60E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="C6354_RS18250"
                     /protein_end="954"
                     /protein_start="945"
                     /score="2.5"
                     /tool="antismash"
                     /translation="GKVDQRALP"
     CDS_motif       complement(3491..3556)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0011"
                     /evalue="1.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="C6354_RS18250"
                     /protein_end="876"
                     /protein_start="854"
                     /score="36.1"
                     /tool="antismash"
                     /translation="YIGRTDDQVKIRGYRIEPKEIE"
     aSDomain        complement(3521..4711)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6354_RS18250_AMP-binding.1"
                     /evalue="3.30E-105"
                     /label="C6354_RS18250_AMP-binding.1"
                     /locus_tag="C6354_RS18250"
                     /protein_end="866"
                     /protein_start="469"
                     /score="343.9"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="FERQAAQTPDQIAIRYEGGSVTYKELNESANKLARLLQKRGLKRE
                     EPVGVMLGRSPSLAAAVLGILKAGGAFVPIDPGSPKERIRYVIENSGCVHVVTERHQSL
                     PAEQTLQVTYIEEAGTEADGSNVQSINTADDLLYMIYTSGTTGKPKGVLLEHKNMANLL
                     SDQLTNTDIDFCTNVLQYASLAFDVCYQELFSVLLSGGTLCIVPESIKRDVSQLYSFID
                     QHKTEVVFFPTAFVKMLFNEEGYAQSFPRCVKHVITAGEQLTISRLFRQTLRLHGMHLH
                     NHYGPSETHVVSTYTISAGDDIPEHPPIGKPIHHNKMYILSKNRQLQPLGIAGELYISG
                     ANTGRGYVNNPALTEEKFLPDPFRKGAVMYRTGDLARLRADGQIEYIGRTDDQVKIR"
     CDS_motif       complement(3638..3727)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0010"
                     /evalue="1.20E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="C6354_RS18250"
                     /protein_end="827"
                     /protein_start="797"
                     /score="40.1"
                     /tool="antismash"
                     /translation="PLGIAGELYISGANTGRGYVNNPALTEEKF"
     CDS_motif       complement(3836..3862)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0009"
                     /evalue="4.60E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="C6354_RS18250"
                     /protein_end="761"
                     /protein_start="752"
                     /score="4.1"
                     /tool="antismash"
                     /translation="YGPSETHVV"
     CDS_motif       complement(4244..4300)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0008"
                     /evalue="5.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="C6354_RS18250"
                     /protein_end="625"
                     /protein_start="606"
                     /score="28.2"
                     /tool="antismash"
                     /translation="YMIYTSGTTGKPKGVLLEH"
     CDS_motif       complement(4484..4525)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0007"
                     /evalue="2.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="C6354_RS18250"
                     /protein_end="545"
                     /protein_start="531"
                     /score="17.2"
                     /tool="antismash"
                     /translation="LGILKAGGAFVPID"
     CDS_motif       complement(5054..5170)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0006"
                     /evalue="4.50E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="C6354_RS18250"
                     /protein_end="355"
                     /protein_start="316"
                     /score="64.1"
                     /tool="antismash"
                     /translation="QKDALKGQAYSYHPLYDIQANSQVKQGLIDHILVFENYP"
     aSDomain        complement(5210..6097)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6354_RS18250_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.30E-113"
                     /label="C6354_RS18250_Condensation_DCL.1"
                     /locus_tag="C6354_RS18250"
                     /protein_end="303"
                     /protein_start="7"
                     /score="371.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="QDIYPLSYMQEGMLFHSLLQKESQAYAEQASFSITGKVDTRVFEE
                     SVHALFERHDIFRTIFISQNVSVPQQVVLKERNVSIIEENLTNLNKADQIKYIEEAKRR
                     DREKGFHLQKDMLMRVTLLQTGECEYTCIWSFHHIIMDGWCLGIVLKEFFQIYASRLRR
                     TPLTLEPAVPYGTYIKWLMEQDKEKAASYWERYLEGFEQQTVLPKQKKSGESRQEEVTF
                     SFSKEDTAKLKELAVKEEVTLSTIFHTLWGILLQAYNQTEDAVFGSVISGRPSEIEGIE
                     RMIGLFINTVPVRIS"
     CDS_motif       complement(5216..5311)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0005"
                     /evalue="1.20E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="C6354_RS18250"
                     /protein_end="301"
                     /protein_start="269"
                     /score="62.7"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPSEIEGIERMIGLFINTVPVR"
     CDS_motif       complement(5543..5581)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0004"
                     /evalue="1.90E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="C6354_RS18250"
                     /protein_end="192"
                     /protein_start="179"
                     /score="8.1"
                     /tool="antismash"
                     /translation="PYGTYIKWLMEQD"
     CDS_motif       complement(5627..5692)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0003"
                     /evalue="5.50E-13"
                     /label="C3_DCL_135-156"
                     /locus_tag="C6354_RS18250"
                     /protein_end="164"
                     /protein_start="142"
                     /score="41.2"
                     /tool="antismash"
                     /translation="FHHIIMDGWCLGIVLKEFFQIY"
     CDS_motif       complement(5912..6025)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0002"
                     /evalue="8.60E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="C6354_RS18250"
                     /protein_end="69"
                     /protein_start="31"
                     /score="47.0"
                     /tool="antismash"
                     /translation="AYAEQASFSITGKVDTRVFEESVHALFERHDIFRTIFI"
     aSDomain        complement(6029..6118)
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6354_RS18250_NRPS-COM_Nterm.1"
                     /evalue="3.90E-19"
                     /label="C6354_RS18250_NRPS-COM_Nterm.1"
                     /locus_tag="C6354_RS18250"
                     /protein_end="30"
                     /protein_start="0"
                     /score="59.6"
                     /tool="antismash"
                     /translation="MTKKNAIQDIYPLSYMQEGMLFHSLLQKES"
     CDS_motif       complement(6047..6088)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18250_0001"
                     /evalue="9.60E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="C6354_RS18250"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.4"
                     /tool="antismash"
                     /translation="YPLSYMQEGMLFHS"
     gene            complement(6144..>8732)
                     /locus_tag="C6354_RS18255"
                     /old_locus_tag="C6354_18245"
                     /pseudo=""
     CDS             complement(6144..>8732)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: AMP-binding (1-211). E-value: 4.5e-56.
                     Score: 182.1. Matches aSDomain:
                     nrpspksdomains_C6354_RS18255_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (316-384). E-value: 2e-25. Score:
                     80.8. Matches aSDomain: nrpspksdomains_C6354_RS18255_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (393-696). E-value:
                     4.1e-163. Score: 536.0. Matches aSDomain:
                     nrpspksdomains_C6354_RS18255_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (701-855). E-value: 3.7e-51.
                     Score: 164.9. Matches aSDomain:
                     nrpspksdomains_C6354_RS18255_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007611861.1"
                     /locus_tag="C6354_RS18255"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18245"
                     /product="condensation domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="AMP-binding (E-value: 8.4e-72, bitscore:
                     232.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-15, bitscore:
                     47.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.1e-76, bitscore:
                     247.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SLGFDVTTFEIFGPLLNGASLYVSDQETYLDSDVLETFIQQNGIT
                     TLWLTSSLFNHLSEQNEHVFSGLSRLIIGGEALSPSHVNRVRNALPHLSVWNGYGPTEN
                     TTFSTCFLIEQSYDHSIPIGRPVGNSTAYIINSRGTPQPIGVIGELCTGGDGVARGYFG
                     RPELTEEKFVPNPFVPGERMYRTGDLARWLPDGTIEYAGRMDDQVKIRGYRVELGEIEA
                     ALRSLDGVKEAAVSVRTGQSGNKELIAYMSLQADMDTEKVRSSLSKQLPNYMVPAYMME
                     LEKLPLTPNGKLDRKNLPEPQLALQTAYTAPRNELEEQLSVIWQEVLGTKQVGIEDSFF
                     ELGGDSIKALQVAARLGRYGRKMTASDLFRHPSIKELAPLIRKAERVIDQRPVEGDIPW
                     TPIQHWFLSQRMENRNHFNQSVMMFSSDALHKQPLKQALEHLVIHHDALRITVSSENES
                     IRQINHGIQKDELYSLDIWDLSETDTWEREIEDEVTALQQRMDIEKGPLLKAGWFKTRS
                     GDYLFITVHHLAVDGVSWRILLEDLSAAYTQAVKGQPVQLPPKTDSFKQYAVRLSEYAK
                     SSKLMREEEYWRFIEEETAAELPYEKPQYQTGADSIRQTVSFTLTEEETYVLLQQVNRA
                     YHTDTQDILLTAAALALRDWTGGGRLRIAMEGHGREHIMPELDISRTVGWFTSMYPVLI
                     DLNTAGAELGTAVKTVKDTLGRIPDKGIGYGILKYMTPSEQKTIRFRQAPEISFNYLGQ
                     FNDTEDQHTFSLSGLASGHDITPTWQREQAVEMSAMAAQHKLHFSLSYPPSRFRKETME
                     HLLQTLQQYLRDIMAHCTGKEEAEKTVSDFSSKTLTSDDLDSIASFVEEL"
     aSDomain        complement(6165..6626)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6354_RS18255_TIGR01720.1"
                     /evalue="3.70E-51"
                     /label="C6354_RS18255_TIGR01720.1"
                     /locus_tag="C6354_RS18255"
                     /protein_end="855"
                     /protein_start="701"
                     /score="164.9"
                     /tool="antismash"
                     /translation="ELGTAVKTVKDTLGRIPDKGIGYGILKYMTPSEQKTIRFRQAPEI
                     SFNYLGQFNDTEDQHTFSLSGLASGHDITPTWQREQAVEMSAMAAQHKLHFSLSYPPSR
                     FRKETMEHLLQTLQQYLRDIMAHCTGKEEAEKTVSDFSSKTLTSDDLDSI"
     aSModule        complement(6165..8726)
                     /complete
                     /domains="nrpspksdomains_C6354_RS18255_AMP-binding.1"
                     /domains="nrpspksdomains_C6354_RS18255_PCP.1"
                     /domains="nrpspksdomains_C6354_RS18255_Epimerization.1"
                     /domains="nrpspksdomains_C6354_RS18255_TIGR01720.1"
                     /locus_tags="C6354_RS18255"
                     /monomer_pairings="X -> D-X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(6471..6500)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18255_0008"
                     /evalue="2.50E-03"
                     /label="NRPS-E7"
                     /locus_tag="C6354_RS18255"
                     /protein_end="753"
                     /protein_start="743"
                     /score="10.3"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     CDS_motif       complement(6540..6602)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18255_0007"
                     /evalue="4.80E-10"
                     /label="NRPS-E6"
                     /locus_tag="C6354_RS18255"
                     /protein_end="730"
                     /protein_start="709"
                     /score="31.6"
                     /tool="antismash"
                     /translation="VKDTLGRIPDKGIGYGILKYM"
     aSDomain        complement(6642..7550)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6354_RS18255_Epimerization.1"
                     /evalue="4.10E-163"
                     /label="C6354_RS18255_Epimerization.1"
                     /locus_tag="C6354_RS18255"
                     /protein_end="696"
                     /protein_start="393"
                     /score="536.0"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLAVDG"
                     /tool="antismash"
                     /translation="EGDIPWTPIQHWFLSQRMENRNHFNQSVMMFSSDALHKQPLKQAL
                     EHLVIHHDALRITVSSENESIRQINHGIQKDELYSLDIWDLSETDTWEREIEDEVTALQ
                     QRMDIEKGPLLKAGWFKTRSGDYLFITVHHLAVDGVSWRILLEDLSAAYTQAVKGQPVQ
                     LPPKTDSFKQYAVRLSEYAKSSKLMREEEYWRFIEEETAAELPYEKPQYQTGADSIRQT
                     VSFTLTEEETYVLLQQVNRAYHTDTQDILLTAAALALRDWTGGGRLRIAMEGHGREHIM
                     PELDISRTVGWFTSMYPVLIDL"
     CDS_motif       complement(6651..6698)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18255_0006"
                     /evalue="9.90E-10"
                     /label="NRPS-E5"
                     /locus_tag="C6354_RS18255"
                     /protein_end="693"
                     /protein_start="677"
                     /score="30.2"
                     /tool="antismash"
                     /translation="DISRTVGWFTSMYPVL"
     CDS_motif       complement(7104..7169)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18255_0005"
                     /evalue="1.40E-12"
                     /label="NRPS-E2"
                     /locus_tag="C6354_RS18255"
                     /protein_end="542"
                     /protein_start="520"
                     /score="39.6"
                     /tool="antismash"
                     /translation="LFITVHHLAVDGVSWRILLEDL"
     CDS_motif       complement(7377..7439)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18255_0004"
                     /evalue="2.30E-03"
                     /label="C2_LCL_024-062"
                     /locus_tag="C6354_RS18255"
                     /protein_end="451"
                     /protein_start="430"
                     /score="10.4"
                     /tool="antismash"
                     /translation="KQPLKQALEHLVIHHDALRIT"
     CDS_motif       complement(7509..7535)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18255_0003"
                     /evalue="1.40E-03"
                     /label="NRPS-E1"
                     /locus_tag="C6354_RS18255"
                     /protein_end="407"
                     /protein_start="398"
                     /score="11.7"
                     /tool="antismash"
                     /translation="WTPIQHWFL"
     aSDomain        complement(7578..7781)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6354_RS18255_PCP.1"
                     /evalue="2.00E-25"
                     /label="C6354_RS18255_PCP.1"
                     /locus_tag="C6354_RS18255"
                     /protein_end="384"
                     /protein_start="316"
                     /score="80.8"
                     /tool="antismash"
                     /translation="EEQLSVIWQEVLGTKQVGIEDSFFELGGDSIKALQVAARLGRYGR
                     KMTASDLFRHPSIKELAPLIRKA"
     CDS_motif       complement(8067..8132)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18255_0002"
                     /evalue="8.80E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="C6354_RS18255"
                     /protein_end="221"
                     /protein_start="199"
                     /score="40.0"
                     /tool="antismash"
                     /translation="YAGRMDDQVKIRGYRVELGEIE"
     aSDomain        complement(8097..8726)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6354_RS18255_AMP-binding.1"
                     /evalue="4.50E-56"
                     /label="C6354_RS18255_AMP-binding.1"
                     /locus_tag="C6354_RS18255"
                     /protein_end="211"
                     /protein_start="1"
                     /score="182.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LGFDVTTFEIFGPLLNGASLYVSDQETYLDSDVLETFIQQNGITT
                     LWLTSSLFNHLSEQNEHVFSGLSRLIIGGEALSPSHVNRVRNALPHLSVWNGYGPTENT
                     TFSTCFLIEQSYDHSIPIGRPVGNSTAYIINSRGTPQPIGVIGELCTGGDGVARGYFGR
                     PELTEEKFVPNPFVPGERMYRTGDLARWLPDGTIEYAGRMDDQVKIR"
     CDS_motif       complement(8214..8303)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18255_0001"
                     /evalue="5.80E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="C6354_RS18255"
                     /protein_end="172"
                     /protein_start="142"
                     /score="53.7"
                     /tool="antismash"
                     /translation="PIGVIGELCTGGDGVARGYFGRPELTEEKF"
     gene            complement(8913..9323)
                     /locus_tag="C6354_RS18260"
                     /old_locus_tag="C6354_18250"
     CDS             complement(8913..9323)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014315598.1"
                     /locus_tag="C6354_RS18260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18250"
                     /product="DUF421 domain-containing protein"
                     /protein_id="WP_076983292.1"
                     /transl_table=11
                     /translation="MTLKNKSTRSLLLGNPNIIIRDGVMDRDVNQVLSILRQNNVFSVR
                     EVKYGILEANGQISLLLKSKYQKPDLNLPESPVDLPTSLIIDGEILWDNLHELGFDQQW
                     LDNQLTTNGYDNVKRILYADWRESEGIHVSPK"
     gene            complement(<9384..9437)
                     /locus_tag="C6354_RS19475"
                     /pseudo=""
     CDS             complement(<9384..9437)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044606.2"
                     /locus_tag="C6354_RS19475"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLVLGDFLGNNIYEDKVG"
     misc_feature    complement(9615..9628)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.08"
                     /tool="antismash"
     gene            complement(9685..11178)
                     /locus_tag="C6354_RS18265"
                     /old_locus_tag="C6354_18255"
     CDS             complement(9685..11178)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017695658.1"
                     /locus_tag="C6354_RS18265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18255"
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="WP_017417921.1"
                     /transl_table=11
                     /translation="MEWIFYLYLLNTFFILFIAIWEVRRPAKALNWIIIVLFLPVIGFW
                     LYLSISNPKFIHRKRLTCSKNESNKLPETFGASASVIANALRHFTVNGLRMGQVQVFNN
                     GIAKYDQLLVSLQKAQETIDLEYFIYRNDQIGNRITELLIEKALNGVQVRFMRDSLGSY
                     KFPREKIRQMVEAGIECRTIFPLRFPWILSNWNYRDHCKIVTIDRKESFTGGMNVGYEY
                     TGLKPDVGFWRDTHLQIIGEATGDLQTVFDVHWEIAVPERIKSKTNLKTKSEVTKINSI
                     GRADHSKWSAELGSELSTLDDKEMDISGKTRTLHKAYIHTLEGNPGIPTPVIRQAYFIC
                     ITQATKTIDLTTPYFVPETDIIMALKTAVTRGVRVRLLVPRHNNQKIVGLASRTYYGEL
                     IEAGVQIYQYDKGMIHAKVLTIDEEIAAVGSANYDMRSFRLNYEVCQVVYSADVARELT
                     EQFERDLTDSVPLRIEDLLQRSLTERIVEQGARVLSPLL"
     gene            complement(11530..12037)
                     /locus_tag="C6354_RS18270"
                     /old_locus_tag="C6354_18260"
                     /pseudo=""
     CDS             complement(11530..12037)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016108108.1"
                     /locus_tag="C6354_RS18270"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18260"
                     /product="DUF421 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSIFLVKVIFIYIVFIVAVNILGKSALAQLTPHDFGAILFLS"
     gene            complement(12154..13014)
                     /locus_tag="C6354_RS18275"
                     /old_locus_tag="C6354_18265"
     CDS             complement(12154..13014)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013352388.1"
                     /locus_tag="C6354_RS18275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18265"
                     /product="DUF421 domain-containing protein"
                     /protein_id="WP_017417922.1"
                     /transl_table=11
                     /translation="MPEWLDVAVRSALFVALLFFVTKWLRKKQISELTFFEYVTGISIG
                     NIGAEVTIGLERNIFHGIIGIVIFAAIPFFAGLISLKSKRFRNFIEGKATVFIKDGKIM
                     EDNLKKERYTTDELLDLLRKKDVFQVSDVEFAVLEATGDLSVMLKKENQPLTAKDINLK
                     VASIKEPQTIIMDGTIMDEPLATIGRSRAWLQTELEKLGVTIENVFLGQVNSYGELTID
                     LFDDKLQVAPPQERPLILSTLKKCQADLELFALGTESKDAKQMYRLNSEKLQEAIDKVT
                     PILKG"
     gene            complement(13044..13250)
                     /locus_tag="C6354_RS18280"
                     /old_locus_tag="C6354_18270"
     CDS             complement(13044..13250)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009336483.1"
                     /locus_tag="C6354_RS18280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18270"
                     /product="DUF1657 domain-containing protein"
                     /protein_id="WP_009336483.1"
                     /transl_table=11
                     /translation="MTVGSDVKQCFASLKGVEASLSSLALRTLDDESKRTLHEAMMVVH
                     EVTKDLKKRVGELEGEELQYKGF"
     gene            complement(13262..13612)
                     /gene="spoVAE"
                     /locus_tag="C6354_RS18285"
                     /old_locus_tag="C6354_18275"
     CDS             complement(13262..13612)
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoVAE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417923.1"
                     /locus_tag="C6354_RS18285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18275"
                     /product="stage V sporulation protein AE"
                     /protein_id="WP_017417923.1"
                     /transl_table=11
                     /translation="MIYFWAFVVGGLICIIGQIMFDVFKLTPGHTLSALVVIGALLDGF
                     GLYEPLIDFAGAGATVPITNFGNSLVHGAMQEAEKHGLVGILTGMFEVTSSGISAAIVF
                     GMIGALIFKPKG"
     gene            complement(13609..14628)
                     /gene="spoVAD"
                     /locus_tag="C6354_RS18290"
                     /old_locus_tag="C6354_18280"
     CDS             complement(13609..14628)
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /function="Polyketide synthase modules and related
                     proteins"
                     /gene="spoVAD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017697693.1"
                     /locus_tag="C6354_RS18290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18280"
                     /product="stage V sporulation protein AD"
                     /protein_id="WP_013352386.1"
                     /transl_table=11
                     /translation="MLAGHRTWIFEQKPVIISTGTVGGPFEANGAIPDDFDTLHADLWL
                     GQDSYEKAHKILFEEACQKAMEKGGIQKDQVQFILAGDLINQITPTSFASRTIGAPYFG
                     LFGACSTSMEGLALGAYIVNTKGAKYLLTGASSHDTAVEKQFRYPTEYGGQKPPTAQWT
                     VTGAGAALLSDSGEGPHVTSATIGRVIDMGLTDPFNMGGAMAPAAVDTIEAHLKERNVE
                     PSYYDLIVTGDLGQIGQEVSMDLFKKHGTPISEEQYQDCGLMIYREGQPVLAGASGAGC
                     SATVVYGHLLNRMKNGEFKRMLVVATGALLSPLSFQQNETIPCIAHAVSIEYGGEQLT"
     gene            complement(14628..15107)
                     /gene="spoVAC"
                     /locus_tag="C6354_RS18295"
                     /old_locus_tag="C6354_18285"
     CDS             complement(14628..15107)
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoVAC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009336486.1"
                     /locus_tag="C6354_RS18295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18285"
                     /product="stage V sporulation protein AC"
                     /protein_id="WP_013352385.1"
                     /transl_table=11
                     /translation="MSNNQKKQLTPVQQEYQKLQKQREIKRPVVKNCIKAFLIGGLICL
                     IGQLISDFYIYYFDFTEQTAGNPTVGTLIFITMLLTGFGVYDRMAQFGGAGTAVPVTGF
                     GNAVISPAIEHRSEGFVLGVGGNIFKLAGAVILFGVFSAFVIALIKTTLIQWGGL"
     gene            complement(15125..15598)
                     /locus_tag="C6354_RS18300"
                     /old_locus_tag="C6354_18290"
     CDS             complement(15125..15598)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009336487.1"
                     /locus_tag="C6354_RS18300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18290"
                     /product="YhcN/YlaJ family sporulation lipoprotein"
                     /protein_id="WP_009336487.1"
                     /transl_table=11
                     /translation="MKDKITTLKNLLFIIMVIGFASGCNGNQNEFIQGNSTFGISQVHT
                     SKPIDQSVANHAKEKIIAKEDITDVKAVNTDKELMAAIKVENFDRFRLKSIEKSVKSDL
                     EKKYPDYKVFVSTDKKIFWELEKVEQRLKKNDMNKKNLKNDLNKLKSLMKEQT"
     gene            complement(15680..15886)
                     /locus_tag="C6354_RS18305"
                     /old_locus_tag="C6354_18295"
     CDS             complement(15680..15886)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017695330.1"
                     /locus_tag="C6354_RS18305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18295"
                     /product="DUF1657 domain-containing protein"
                     /protein_id="WP_013352384.1"
                     /transl_table=11
                     /translation="MTVINDVKTALAGLKSAQASFETFALSTDNQQAKQLYQDAAKQTQ
                     SVVDSIEPRVQQIEQEEPQYKQQ"
     misc_feature    16169..16186
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.23"
                     /tool="antismash"
     gene            16371..16511
                     /locus_tag="C6354_RS19000"
     CDS             16371..16511
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013354185.1"
                     /locus_tag="C6354_RS19000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_013354185.1"
                     /transl_table=11
                     /translation="MTTKQKRKSFQRLTLKPKKDIEEIKLGIKLGEKKETKNPRLGERD
                     V"
     misc_feature    16549..16561
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     misc_feature    16694..16709
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.85"
                     /tool="antismash"
     gene            16913..17365
                     /locus_tag="C6354_RS18315"
                     /old_locus_tag="C6354_18305"
     CDS             16913..17365
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701229.1"
                     /locus_tag="C6354_RS18315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18305"
                     /product="hypothetical protein"
                     /protein_id="WP_000701228.1"
                     /transl_table=11
                     /translation="MKIPKTAKVSIPFPSVWGIDASIAGRSIIRGILTIDSIVDNKVVG
                     TVNFRGIPIPINGYWDESAKQISFDSPYASFFGNLTIIDETAISIRHFILSGRFIMKPP
                     SLLAGEYGNWIATTFTTRLGPPIYTNVLPPAGAFSVSSMLLGQQLF"
     gene            complement(17615..18190)
                     /locus_tag="C6354_RS18320"
                     /old_locus_tag="C6354_18310"
     CDS             complement(17615..18190)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001169292.1"
                     /locus_tag="C6354_RS18320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18310"
                     /product="recombinase family protein"
                     /protein_id="WP_001169292.1"
                     /transl_table=11
                     /translation="MQKIGYVRVSSTSQNPSRQFRQLNEIGMDIIYEEKISGATKDREQ
                     LQKMLEDLQEGDIIYVTDLTRITRSTQDLFELIDLIRNKKASLKSLKDTWLDLSEDNPY
                     SQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKE
                     GNMTVNQICEITNVSRASLYRKLSEGKK"
     misc_feature    complement(18179..18193)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.17"
                     /tool="antismash"
     misc_feature    complement(18301..18315)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.51"
                     /tool="antismash"
     gene            18338..21304
                     /locus_tag="C6354_RS18325"
                     /old_locus_tag="C6354_18315"
     CDS             18338..21304
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /locus_tag="C6354_RS18325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18315"
                     /product="Tn3 family transposase"
                     /protein_id="WP_065180827.1"
                     /transl_table=11
                     /translation="MKIARGRELLTLEQRQDFMQIPEDEWILGTYFTFSKRDLEIVNKR
                     RREENRLGFAVQLAVLRYPGWPYTHIKSIPESVIHYISKQIGATPSSISLYPQRENTLW
                     DHLKELRSEYDFVTFTLREYRIAFKHLHQLAFENGDAIHLLHECIDFLRKNKIILPAIT
                     TLERMVWEARAMAEKKLFNTVSQSLTNEQKGKLEEIITSQHPSESNKTILGWLKEPPGH
                     PSPETFLKVIERLEYIRGMELETVQISHLHRNRLFQLSRLGSRYEPYAFRDFQENKRYS
                     ILTVYLLHLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIHFTNIGQ
                     ALIKAKKEKLDVFEILESVIEWNSFVSSVEEAQELARPDDYDYLDLLQKRFYSLRKYTP
                     TLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDNSPVDFISKRWKKHLYEDDGTT
                     INRHYYEMAVLTELMEHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQTKENTRLSVSLSF
                     EDYMTERTSSLNKRLKWLATNSNKLDGVSLEKGKLSIERLEKDVPEEAKKFSASLYQML
                     PRIKLTDLLMDIAYITGFHEQFIHASNNRKPDKEETIIIMAALLGMGMNIGLSKMAEAT
                     PGLTYKQLANVSQWRMYEDAMNKAQAVLVNFHHKLQLSSYWGDGTTSSSDGMRMQIGVS
                     SLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLDGLLHHETDLNIVE
                     HYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYPKLEVILRGQINTKV
                     IKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALREMGRIEKTIFILNYIS
                     DESLRRKIQKGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQRASALNIIINAISIWN
                     TLHLTKAVEYQKRSGSFNEELLHHMSPLGWEHINLLGEYHFNSEKMVSLDSLRPLKLS"
     CDS             complement(21281..>22571)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: AMP-binding (215-385). E-value: 7e-50.
                     Score: 161.7. Matches aSDomain:
                     nrpspksdomains_C6354_RS18330_AMP-binding.1"
                     /codon_start=3
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007611861.1"
                     /locus_tag="C6354_RS18330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6354_18320"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_317615488.1"
                     /sec_met_domain="Condensation (E-value: 2.2e-15, bitscore:
                     46.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8.6e-40, bitscore:
                     126.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LAAYNTLLARLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLAIR
                     TEPKGGKRFTDYLAEVRQAALEAYEHQDYPFEELVERLGVQRDTSRNPLFDVMFVLQNM
                     ERESLVLNKLHLAQAADTSHKTAKFDATLYASEGSDGSISFDFEFNTDIYQKQTIEKWL
                     SYFTRILTKVIENQAIPLGDIHVLDDAETNRVIYQFNQTKSDYPRHETISRLFERQAKE
                     TPDARAVVYDGQILTYRELNERANRIAAALRSNGVGPESVVALLTGRTTELASGILGIL
                     KAGGAYLPIGDDVPRERAEWMLKDCKADILLQSDKLDGLPLSGKRLFIEDIQTKAGLSS
                     ENPEPLGGPESLAYMIYTSGSTGAPKGVMIEQRSVIRLVKNSNYIDFTPEDRLLFTSSW
                     GTVRKMRIYNAKPISPTIPPVLTTLRKFQGS"
     gene            complement(21281..>22575)
                     /locus_tag="C6354_RS18330"
                     /old_locus_tag="C6354_18320"
     aSDomain        complement(21416..21925)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6354_RS18330_AMP-binding.1"
                     /evalue="7.00E-50"
                     /label="C6354_RS18330_AMP-binding.1"
                     /locus_tag="C6354_RS18330"
                     /protein_end="385"
                     /protein_start="215"
                     /score="161.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FERQAKETPDARAVVYDGQILTYRELNERANRIAAALRSNGVGPE
                     SVVALLTGRTTELASGILGILKAGGAYLPIGDDVPRERAEWMLKDCKADILLQSDKLDG
                     LPLSGKRLFIEDIQTKAGLSSENPEPLGGPESLAYMIYTSGSTGAPKGVMIEQRSVIRL
                     VKNSNYI"
     CDS_motif       complement(21458..21514)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18330_0004"
                     /evalue="3.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="C6354_RS18330"
                     /protein_end="371"
                     /protein_start="352"
                     /score="31.8"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGAPKGVMIE"
     CDS_motif       complement(21701..21739)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18330_0003"
                     /evalue="4.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="C6354_RS18330"
                     /protein_end="290"
                     /protein_start="277"
                     /score="16.7"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPI"
     CDS_motif       complement(22268..22387)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18330_0002"
                     /evalue="6.50E-25"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="C6354_RS18330"
                     /protein_end="101"
                     /protein_start="61"
                     /score="79.7"
                     /tool="antismash"
                     /translation="RQAALEAYEHQDYPFEELVERLGVQRDTSRNPLFDVMFVL"
     CDS_motif       complement(22436..22525)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6354_RS18330_0001"
                     /evalue="1.10E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="C6354_RS18330"
                     /protein_end="45"
                     /protein_start="15"
                     /score="49.9"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLAIR"
ORIGIN
        1 cgagagccgt cgcttttaac gaatggccgc cccgctcaaa aaagtgatcc cggatgccga
       61 cgggtccgtt tttcagcacc tcttcccaaa gggcgcaaag cttcatttcc gtgacgttcc
      121 gcggggcggt gtacacctgt ctgtctgccg ctccgccggg agccggcagc gcgcggcggt
      181 caagctttcc gctcggcgtg accggccatt cgctcatctc tataaactga gccggcatca
      241 tgtaggccgg aaggcgtgtt gcaagctccg cccgcacgtc atcgcttttt cgtccttcaa
      301 tataggcgta aagcgcggtt tcgccgtgtt cggtccgggc ggtgaccgcc gcctcacgaa
      361 tgccgtcgat gcgccggatc gccgcttcga tttctcccgg ttcaatccgg tagccgcgga
      421 ctttcacctg tccgtctgaa cgaccgagcc attcgacaag gccgtcttct gtccagcgtg
      481 cgatatcacc cgtctgatac atgcgttctc ccggataaaa cggatcatcg acaaaacgct
      541 cctccgtcag ctcaggccgg ttcagatagc cgcgggccac gcctgtccct gcgatataca
      601 gctctccgat acagcccggc ggcagaagct gtttcttttg atttaaaata tacagccgca
      661 tgttatgtcc ggaactgccg atcggaacat tgtgaaattc ctttccttgc ggcaaatcga
      721 agtacgccgc ttctaccgtc gcttccgtcg gaccgtagga atttgtcaat tccgttcccg
      781 gcagaaggtc ataaaaacgg gaaaccaagt gcgggcccaa ttgttcgccc ccggcaaaaa
      841 ccctttttaa gcaggtcttt ttgatcggct gttttctgga atttatatat tccaagaaag
      901 catgaagcat ggatggcaca aaatgagctg ccgttatgcg gtttttctcc aatgcgttca
      961 gtatcatttc agggtctttc tcgccgcctt gcggaaggag aaaaacagaa gctcccgcga
     1021 tcggccacca aaacagctcc caaatcgaag catcgaaaga gtatgatgtt ttatgcaaaa
     1081 tggtgtcgga atcctttaat ccataacgcg tttgcagcga gtataaaaag tttacggctg
     1141 actgatgttc aacctgcacg ccttttgggc gtcccgtaga accggatgta tagatgatat
     1201 aagccaatga atcaggtttt accggaacat tggggttggc cgcagcttcc gggtttcctg
     1261 tttgcccgct tttcagagag atcgtttctc cctcaaaaag atctggtgcg aaaagttctg
     1321 gttctgccag taagaatttc acgccgctgt ctttcagtaa aaagcgaatc cgctcttccg
     1381 gataatccgg atcaatcggc agatatgcac cgcctgcttt taagacagcg taaatgccga
     1441 tcagcatgtc aggagaacgc cggcccataa tggcagtttt atcctccagc cttattcccc
     1501 gcttgatcag ccggtgcgca agctcattcg ctctttcgtt cagctcctga tacgtaatcg
     1561 aaatgtcatc agttaaaatc gccggacggt ccggcgtttt ttccgcctgt tgttccagca
     1621 gatcatgaag aggctgatga agcggaaacg ccgttttctg caaggggctg aattcttgaa
     1681 gcagagacac ttcttctttt tctgacaaaa cagaaatatc gtctaattcc aaactcggat
     1741 cagctgcggc gttttcggca agtgtcgtga aaaattccgc ccatttttga atcgtttttc
     1801 tctcaaacaa atcggtgctg tattcaaact ggcagtacaa ttcaccggcg ttttcggaga
     1861 tgtacagcga taagtcaaat ttagaaatcg gcaggctgac gtctgccggc tgcagttcaa
     1921 gtccggctgc cctaagcttc tgctgttcca tattttgcag cgcaaatgtt gtgtcaaaca
     1981 gcggatttct ggacatgtcc cgcggcacac cgagcttatc gacgagctct tctaacgggt
     2041 aatcctgatg ttcgtaagcc tcaagcgctg tttggcgaat ttcctttaaa tattctttga
     2101 acgtcatgct tccgtcggga cgcgtcctga aagcgagcgt attgacaaac atgcccagaa
     2161 cggcgtcaag gtcggcatga ggccttcctg caatcggaga cccgacaatc atatcttcct
     2221 gtccgcttaa acgggctaac agaaccgtgt acacaccgag cagcgtcata taaagtgtgc
     2281 atttgttttc tttcgccagc tttttcaact gtgctgtatg tttttcgctg atgacaaatg
     2341 acacccggtc accggaaaag ctccgcaccg ggggacgcgg cttatcagcc ggcaattcaa
     2401 gcacgggaat ctccccggca agccggttca gccagtattc ctcttgtttc cgatatgcgg
     2461 cgcccgcctt aaatgattgc tgccagacgg cataatcttt gtattgaatc cgtaacggcg
     2521 gcagacttct ctcagcatac agctcactga attcacgtat caaaagattg acggatacgc
     2581 cgtctgaaat aatatgatgc atgtcagcta aaagcagatg ccggtctttt tctatttgga
     2641 caaatcccgc ccggaaaaga ggcgctttgc cgagatcgaa cggccggata aacgcttcgg
     2701 ctgattgttc ttttgtaaat gcaaacggca cttcgtcatg aatcctctgc acaggccggc
     2761 cgtttttttc ttcaaaggac gttctgagcg gttcatgccg ccggatcagc tccttgaaca
     2821 cggcttccat cctgtctcgg tcaaacggcc ccttcacctc taaaacggct ggaatgttat
     2881 agctgacacc gccattttca agctggtgaa ggacatacat ccgtttttga gcggatgaga
     2941 caggataagt ttcttttgtt tctgtctttt ctatggatgc gaacggattc tcttctgctt
     3001 caccgatgat tttggcgagt tcttctacag tcggatagct gaagacatca ctcagcggga
     3061 tttgcacgct gcactcttta gctatttttg caacgagtgc cgtcgccttt aatgaatggc
     3121 cgccaagctc gaaaaagtga tcgtgaacgc cgatcgggcc ggtttgaagc acttcttccc
     3181 atatgcgggt aagcttcagt tcggtcacat tccggggagc tgtatatcga cggcccgctg
     3241 cgtacgctga agcttccgga agggcccgct gatcgacttt gccgtttcca gtgagcggaa
     3301 tcgcgtcaac gaaagcccat ttgaccggaa tcatataatc aggcagctcc ttggccaaat
     3361 cacttcgcag ctgagaagga tcagtcgctt gtgagacgct gcagtaggcg cataattcat
     3421 tttcgcccga ctcattcgtt tgaatcagca cggcagcttc tttcgcggca tgatgatttg
     3481 ccaggacggt ttcaatttcc ttcggttcaa tccggtaccc tctgatcttc acttgatcat
     3541 ctgtccggcc gatgtattca atttggccgt ctgcacgcag tcttgccaaa tctccggtcc
     3601 ggtacatgac ggcgcccttt ctgaacggat ccggcaaaaa tttctcttcg gtcagcgccg
     3661 gattgttcac atagcctctt cctgtattcg ctccggaaat atacaattct cccgcaattc
     3721 cgagaggctg aagctgtctg tttttgctga gaatatacat tttgttatga tggatcggtt
     3781 tcccgatcgg cggatgttca ggtatgtcat ctcccgcaga aatcgtatac gttgaaacca
     3841 catgggtttc tgacgggccg taatgattat gcaaatgcat accgtgtaaa cggagcgtct
     3901 gcctgaacaa acgtgagata gtcagctgct ccccggccgt aatgacatgc ttcacacagc
     3961 ggggaaaaga ctgtgcataa ccttcttcat tgaaaagcat cttgacaaac gcagtcggga
     4021 aaaacaccac ctctgttttg tgctgatcaa taaacgaata cagctgagaa acatcccgtt
     4081 tgattgattc cggcacgata caaagggtgc cgccgctcaa gagtactgaa aataactcct
     4141 gatagcagac gtcaaacgcc aaagatgcgt actgcagtac atttgtgcaa aaatcaatat
     4201 ctgtgttcgt caattggtca gaaagaaggt tggccatatt tttatgttcg agcagcacgc
     4261 ccttcggttt ccctgtcgta ccggatgtat aaatcatata aaggaggtcg tccgccgtat
     4321 taatggattg cacattgctt ccgtccgctt ccgtcccggc ctcttctata tatgtaacct
     4381 gcagcgtttg ttccgcgggg agtgactgat gccgctctgt tacaacatgg acgcagccgc
     4441 tgttttcaat gacatatcgg atacgctcct ttggactgcc gggatctatc gggacaaagg
     4501 cgccgcccgc ttttaaaata ccgagaacgg ccgccgctaa agaaggggaa cggccgagca
     4561 tgacgcctac cggctcctcc cgctttaatc cgcgtttttg cagcagacgg gccagcttat
     4621 tagccgattc attcagctct ttgtacgtca ctgacccgcc ttcataccgg atcgcgattt
     4681 gatccggcgt ttgtgcggcc tgccgttcaa acatcgcatg aatcgtgtca tactcaggca
     4741 tttcagtttc ttcagaaatc ggagcaagca gctgctcttt ttcctcagga gtgatgatta
     4801 caagcttatc cggtgtgata tcaggtttgt cgagaatctg ggaaacgata tgtgtcaaat
     4861 gacctttgat attttcgata aattggcggt catacacgct tgaatcgtat ctcattttca
     4921 aatgaatctc gtcacccggc gccaccataa gataaaaact gtaattggtt tcgtcttcca
     4981 tgctgaaatc atggatgtga aaaaggtctt tcgtgtcccc cttgctgttc agcacatcaa
     5041 gctcctgttc aaccggataa ttctcaaaga cgagaatatg atcaattaag ccttgtttta
     5101 cctgtgaatt cgcctgtatg tcataaagcg gatgatagct gtaagcctgt cctttcaaag
     5161 cgtccttttg cacatttttg atcagctttt gaaacgggat gtttgccccg ctgatccgga
     5221 caggcacggt attaataaac aggccgatca ttcgctcgat gccttcgatt tcagacggcc
     5281 ttccggaaat gacagaacca aaaaccgcat cttctgtctg gttatacgcc tgaagcaaaa
     5341 tgccccagag cgtgtggaaa atggtgctca gcgtgacctc ttcttttacg gccagctctt
     5401 tcagcttagc cgtgtcctct tttgaaaagg aaaacgtcac ttcctcttgt ctgctttcgc
     5461 cggatttttt ctgcttcggc agaacagtct gctgctcaaa gccttcaagg taccgctccc
     5521 agtacgaagc ggctttttct ttatcttgct ccatcagcca cttgatgtag gtcccgtacg
     5581 gcacagcggg ctcaagcgtt aacggtgtcc ggcggagccg cgaggcgtat atctggaaga
     5641 actctttcag cacgattccg agacaccagc catccataat gatgtgatgg aaactccata
     5701 tgcacgtata ttcacattct ccggtttgaa gcagcgtcac ccgcatcagc atgtcttttt
     5761 gcagatgaaa ccctttctca cggtctcttc gtttggcttc ttcgatatac ttgatttgat
     5821 cagccttatt taaattagtg agattttcct caataatgct gacgttccgc tcttttaata
     5881 cgacctgctg cggcactgac acgttctggc tgataaagat cgttctgaaa atatcatgtc
     5941 tttcgaaaag ggcatgaacg ctctcttcaa acacgcgggt gtcaaccttc cccgttattg
     6001 aaaaggaggc ctgctcggcg taagcctgtg attccttttg caggagggaa tgaaaaagca
     6061 ttccttcctg catataagac agcggataaa tatcctgaat tgcattcttt tttgtcatgt
     6121 tataatctcc ccgtcgcctt tttctacagt tcctcgacaa aactcgctat gctgtccaaa
     6181 tcatcagatg ttaacgtttt gctgctaaaa tcactaacgg ttttttctgc ttcctctttg
     6241 cctgtgcagt gcgccataat atcacgcaaa tattgctgta aagtttgcag cagatgttcc
     6301 atcgtttctt tgcggaagcg gctcggcgga tagctcaaac tgaagtgcag tttatgttgt
     6361 gcagccatcg cgctcatttc caccgcttgt tcccgctgcc atgtcggcgt gatgtcgtgc
     6421 ccgctcgcaa gaccggataa actgaatgtg tgctgatctt ctgtatcatt gaattgccct
     6481 aaatagttaa agctgatttc aggcgcttgt ctgaagcgga ttgttttttg ttcagatggt
     6541 gtcatgtatt ttaaaatgcc gtagcctatt cctttatccg gtattcttcc gagtgtgtct
     6601 ttgaccgttt ttacagccgt tccaagctca gcgcctgctg tgttcaagtc aatgagcacc
     6661 gggtacatgg aggtaaacca gcctacggtg cggctgatgt cgagctccgg catgatgtgc
     6721 tctctcccgt gcccttccat cgcgatgcgc agtctgccgc cccctgtcca gtcccgtaaa
     6781 gccaaagctg cggcagtcag aagaatatct tgcgtatcgg tatggtaggc ccggttgacc
     6841 tgctgaagca aaacgtacgt ttcttcttct gtaagcgtaa agcttaccgt ttgccgaatg
     6901 ctgtcggctc ccgtctgata ctgcggtttt tcataaggaa gttcggcggc tgtttcctct
     6961 tcaataaaac gccaatattc ttcttcacgc atcagcttgc tgctttttgc gtattctgaa
     7021 agccttacgg cgtattgctt aaacgaatcg gtctttggcg gaagctggac cggctgacct
     7081 tttacggctt gtgtgtaagc ggcagataaa tcctccagca gaatacgcca tgacactccg
     7141 tcaaccgcca ggtgatgtac ggtgatgaat aaataatccc ctgaccgggt tttgaaccag
     7201 ccggctttta ataacggccc tttttcaata tccatccgct gttggagcgc agtaacttca
     7261 tcttctattt ctctttccca agtatctgtc tcagacagat cccaaatgtc caagctgtac
     7321 agttcatctt tttgaatacc gtgattgatt tgtctgatac tttcgttttc tgaactgacg
     7381 gtgatccgga gtgcatcatg atgaatgaca agatgctcca aagcttgttt gagcggctgt
     7441 ttatgcaatg cgtcagagct gaacatcatg acggactgat tgaaatgatt tctgttttcc
     7501 atccgctgtg ataaaaacca gtgctgaatg ggtgtccaag gtatgtctcc ttccaccggc
     7561 cgctgatcga tgactctttc cgctttccgg ataagaggcg cgagttcctt aatggacgga
     7621 tgccggaata agtcacttgc cgtcattttc cgcccatagc gtccgagccg tgcggcaact
     7681 tgcagcgctt tgattgaatc gccgcccaac tcaaaaaatg agtcctcaat cccgacttgt
     7741 tttgtgccga gcacttcctg ccagatcacg gaaagctgtt cttcaagctc attgcgggga
     7801 gctgtgtacg cggtttgaag cgcgagctgc ggttcgggca gatttttccg atccaattta
     7861 ccgttcggcg taagcggcag cttctcaagt tccatcatat aggccggaac catgtaattc
     7921 ggcagttgct tagacagtga agaacgcact ttttctgtat ccatgtccgc ctgcagactc
     7981 atatatgcga tcagttcttt attgccggac tgcccggttc tgactgacac ggcagcttct
     8041 ttcacgccgt ccaggctcct cagtgcggct tcaatctctc ccagctcgac ccgataaccg
     8101 cggattttca cttgatcatc catccgcccg gcatattcga tcgttccgtc cggcagccag
     8161 cgggctaaat ctccggtgcg gtacatccgt tctcctggaa caaaaggatt tgggacgaat
     8221 ttttcttccg tcagctcagg gcggccgaag tatcctcttg ccacaccgtc tcctccagtg
     8281 cataattcgc cgatgacgcc gatcggctgc ggtgttcccc tgctgtttat gatatatgcg
     8341 gttgaatttc cgacagggcg gccgatcggg attgaatgat cgtatgattg ttcaatcaaa
     8401 aagcaagtcg agaacgtcgt gttttcagtc ggtccgtatc cattccatac tgagagatgc
     8461 ggcagcgcat tccgaacccg gtttacatgg ctcggggaca gtgcttcccc gccgataatc
     8521 aatcgggata atccggaaaa cacgtgttca ttttgttctg ataaatggtt gaacagagac
     8581 gatgtcagcc acagtgtcgt aatgccgttt tgctgtataa atgtttccag aacatcagag
     8641 tcgagatagg tttcctggtc acttacatat aaagaagcgc cgtttaaaag cggaccgaat
     8701 atttcaaatg tcgtaacgtc aaatcctaat gatggggtag cgtcaggaaa atgcggattt
     8761 acaacgttaa ggaaaccaaa atataaaaag tctaatttct cggtgttata agtgaaaaat
     8821 taggctttag ttacttcatt aaagcgcctg attgttgaag actaaagttt atattcacca
     8881 agaaaattga tgtgctctta tcctaacaaa ttttatttag gacttacatg tatgccttca
     8941 ctctctcgcc aatctgcgta aagtatacgc tttacattat catatccatt ggtagttaat
     9001 tggttatcta accactgttg atcaaatccg agttcatgta aattatccca taaaatttcc
     9061 ccatctataa ttaacgatgt tgggaggtct actggacttt ctggaagatt gagatctggt
     9121 ttttgatact tggattttaa taataaactt atttgcccat tagcttccaa tataccgtat
     9181 ttgacttcgc gaactgaaaa gacattattt tgacggagta tactcaatac ttgatttaca
     9241 tctctgtcca taacaccatc tcgaatgatg atgttaggat tgcctaataa gagagaacgt
     9301 gtcgatttat tttttagagt cataaactct attcccaaca taagaaacgt ccacaatccg
     9361 atggcatata aaaaatgaaa aatccctacc ttatcttcat aaatgttatt tcctaaaaaa
     9421 tctccaagta ctaacacaaa aactaagtga aacggggttt aactgataga tggatgttct
     9481 gcctgttatg ataatgataa aaaataaagt tgcaaaacct actatgactt tgattgtcag
     9541 taaacccaaa aaaacttcac ccaaaattta ttcctccatt ttatatttca ctcgatttca
     9601 aaaatcctca tgttttaaaa tatttatatt acaacatgta agctaattaa aatcagaaag
     9661 ataaataata ccggtttttt caacttataa taatggagaa agcacgcgag caccctgttc
     9721 aacaatgcgc tcggtcaggg atcgttgcaa caagtcttca attcttaatg gtacagaatc
     9781 agtaagatcc ctctcgaact gctctgtgag ttcccttgcc acatcagcac tgtacacgac
     9841 ttgacacacc tcataattca ggcgaaaact tctcatatca tagtttgctg agcctacggc
     9901 agcaatctcc tcatcgatgg tcaacacctt cgcatgtatc attcctttgt cgtactggta
     9961 gatttgaact ccagcttcta taagttctcc gtaataagta cggcttgcaa gacccacgat
    10021 tttttgatta ttgtggcgag gaaccagcaa tcttacacgg acaccacgag ttactgctgt
    10081 ctttaatgcc atgataatat ccgtttctgg tacaaaatag ggtgttgtta aatcaatagt
    10141 cttggtcgcc tgtgttatac atataaagta agcttgccga atgactgggg taggaattcc
    10201 agggtttcct tccaacgtat ggatatacgc tttatgcaat gtcctagttt ttccggatat
    10261 gtccatttct ttatcatcaa gggtgctcaa ctctgatccc aattcggctg accatttgga
    10321 atgatctgct ctgccgattg aattgatttt cgttacctct gattttgttt tcaaatttgt
    10381 ttttgatttt atcctttccg gcacagcgat ttcccaatga acatcaaaaa cagtctgcaa
    10441 gtcgcctgtt gcttccccta taatttgcaa atgagtgtcc ctccaaaatc ctacgtctgg
    10501 ctttaatcct gtatattcat acccaacgtt cataccgcca gtaaaggatt cctttctgtc
    10561 aatcgtcaca atcttacaat gatcccgata attccaattg gacaaaatcc agggaaatcg
    10621 cagaggaaat attgtcctgc attctatccc tgcttcaacc atctgccgga ttttttcacg
    10681 cgggaattta taactcccca agctatctct cataaaacga acctgcactc catttaatgc
    10741 tttttcgatt agcagttctg tgattcgatt accaatttgg tcgttccgat agatgaaata
    10801 ttccagatca atggtttctt gggctttttg cagggataca aggagttgat catattttgc
    10861 tatcccattg ttaaacactt ggacttggcc cattcgaagc ccattcacag tgaaatgccg
    10921 taaagcattg gcaattaccg atgctgaagc accgaatgtc tcaggtaatt tgttagattc
    10981 atttttagaa caggtcaatc tttttcgatg aataaactta gggtttgata tgctaagata
    11041 tagccagaaa ccaatgacag gtaaaaaaag gacgattatt atccaattca aagccttggc
    11101 aggccgacga acttcccaaa ttgctatgaa taagataaag aacgtattta acaggtatag
    11161 ataaaaaatc cactccaact ggaatccctc cttctgttac tcttaacatg tacaaactat
    11221 gtaaccagta tacgtatgga tatgaaggga ttgtctgtta tatattatgg actaccttta
    11281 taagaacttg tataagatat taagaacgaa aaaaagagaa ttaaggttgg gaaagttctg
    11341 acatcaagaa aggcgtaatg atctgggcac tgtcctaact agagacttag tgattttgaa
    11401 aattaccatc tggtaaattc ctaaatatag gtataatttt ttataaattt ggaaaatgaa
    11461 agtggtaaat gcaataagaa gtaaataaga gaaaacatta atttatattg ggaggaaatc
    11521 gtcttaaaat tagtcgttaa catctttttt gttaatggtt aatgaatgat cggtatctct
    11581 aacagcagca taaaaaaaat ctttgatttg aagatatccc tttgccttta gttcttcctt
    11641 taaccacttt tcatttttgt tgataaattt taatttacgc ttttgcactt tcccttcaat
    11701 gacaacggct atgggtaatc cgcggtattc cactttcata tgtaaatctt ttggagtaat
    11761 aggaactaat tcttttcttg gaaaaatgct aatttcacct gttgcttcca aaatcgcata
    11821 ttcattatcg tgaatatccg gatatcctgt tgttcttaaa ttagacaaca gctcaggtaa
    11881 aggatatcta ctttccttta actttcgatt aagataaaaa aagaatcgct ccaaaatcat
    11941 gaggggtaag ttgggctaga gctgatttcc ctaaaatatt tactgctaca ataaacacaa
    12001 tatagataaa aataacttta actaaaaaaa tagacacttc taacacctcg taaaaaaaat
    12061 tcaccttagt ccgaaattgg actaaggttt ttaaacttat ttcaattaaa aatggtatct
    12121 ttttttcgtc atgtatgaat ctaagctaaa tccttatcct tttaaaatag gggtcacttt
    12181 atcaatggct tcttgtaatt tttcactgtt taacctatac atttgtttgg cgtcttttga
    12241 ttccgttcca agagcaaata gttctaagtc tgcttgacat tttttcaagg ttgaaagaat
    12301 taagggtctt tcttgtgggg gtgcgacttg taatttatcg tcaaacagat caatcgttaa
    12361 ctctccgtaa gaattaacct gtcccagaaa tacattttca atcgttaccc ctagtttttc
    12421 taattcagtt tgtaaccaag cccgacttcg tccaatcgtg gctagtggtt catccattat
    12481 tgtaccatcc ataataatgg tctgaggctc cttgattgaa gcaaccttca agtttatatc
    12541 ctttgctgtt aaaggttgat tttctttctt tagcatcaca gataaatcac ctgttgcctc
    12601 taaaacagca aattctacat cagagacttg aaagacatcc ttcttgcgaa ggagatctaa
    12661 cagttcatct gtcgtatatc tttccttttt taaattatct tccataatct tcccatcttt
    12721 gataaataca gttgcttttc cttctataaa attgcgaaaa cgtttacttt ttaatgaaat
    12781 taaaccagcg aaaaagggaa tagccgcaaa aatgacaatt ccaataattc cgtgaaaaat
    12841 gttccgttca agtcctatag ttacttctgc accaatattc ccaatagaaa taccggtgac
    12901 atattcaaag aaagttagtt cggaaatttg ctttttcctt aaccattttg taacgaaaaa
    12961 taaaagagca acaaataatg ctgagcgtac agctacatct aaccattcag gcactgctta
    13021 cacctcctgt aaatatagtt tttctagaaa cctttgtact gaagttcctc tccttctagt
    13081 tctcctactc ttttttttaa atcttttgtt acttcgtgta ctaccatcat agcctcatgc
    13141 aaagttcgct tcgattcatc atcaagagtc cgtaatgcta aacttgagag acttgcttct
    13201 acccctttta gactggcaaa acactgttta acatctgatc ctactgtcat cctaattctc
    13261 cttatccttt tggcttaaaa attaaagctc ctatcatgcc gaaaacaatg gcagctgaaa
    13321 taccagaact agttacttca aacattcctg tcagtatacc aactaaccca tgtttttctg
    13381 cttcctgcat cgcaccatga acaagcgaat tcccaaaatt tgtaatcgga acggtagccc
    13441 ctgccccagc aaaatcaatc aaaggctcgt atagtccaaa tccatctaaa agcgccccaa
    13501 tcactacaag agcacttaag gtatgacctg gtgtcaattt aaatacatca aacataattt
    13561 gcccaatgat acaaattaaa ccgcctacga caaaagccca aaaatagatc atgttaattg
    13621 ttcacctccg tattcaattg acactgcatg ggcgatacaa ggaattgttt cattttgctg
    13681 aaaggacaac ggtgaaagca aagcacctgt agccacaact aacatgcgtt taaattcacc
    13741 atttttcatg cggtttaata aatgcccata aactaccgtt gctgaacagc ctgcaccgct
    13801 tgcccctgca agaacgggtt gtccttcccg ataaatcata aggccacaat cttggtattg
    13861 ttcttcacta ataggagttc catgcttttt aaatagatcc atggacactt cctgtccgat
    13921 ttggccaagg tcaccggtta caattaaatc gtaataagat ggctcaacat ttcgttcctt
    13981 taaatgggct tcaatggtat caaccgcagc tggcgccata gctcctccca tgttaaatgg
    14041 atctgtcaat cccatatcga ttacacgacc aattgtggca gatgtgacat gaggtccttc
    14101 cccagaatca cttaataggg ctgcacctgc accagtaacc gtccattgtg ccgtaggtgg
    14161 cttttgtcca ccatactcag ttggataccg aaattgtttt tcaacagctg tatcatgact
    14221 ggaagctcct gttaacaaat atttcgctcc ttttgtattt acaatataag cacctagagc
    14281 cagtccttcc atcgaggtag agcaagcacc gaataagcca aaataaggcg ctccaatcgt
    14341 tctgctagcg aaacttgttg gggtgatttg attgattaag tccccagcta ggataaattg
    14401 aacttgatcc ttttgtatgc cccctttttc catggctttt tggcaagcct cttcaaaaag
    14461 gattttatgt gctttctcat aggaatcctg cccaagccat aaatcagcat gaagagtatc
    14521 gaaatcatct gggatagcac cattggcttc aaatggtcca ccaacggttc cagtggagat
    14581 aatgacaggc ttttgttcga agatccatgt acgatgacct gctagcatta taaaccaccc
    14641 cactggatta aagtggtttt aattaaggca atgacaaaag cagaaaaaac accaaataaa
    14701 ataaccgccc ccgctaattt aaatatgttg ccacctacgc ccagtacaaa tccttcgctt
    14761 cgatgctcaa tggcaggcga tataaccgca ttgccaaaac ctgttacagg tacagctgtt
    14821 ccagccccac caaattgggc cattcgatca tatacgccaa aaccagtaag aagcattgta
    14881 ataaaaatta acgtacccac cgtcggattt ccggccgttt gctcagtaaa atcgaaataa
    14941 taaatgtaaa agtctgaaat aagctgacca atcaaacaaa taagtccacc gattaaaaag
    15001 gccttaatac aatttttaac aaccggtctt ttgatctctc gttgtttttg caatttttga
    15061 tattcctgtt gcacaggagt aagttgtttc ttttgattgt tagacataac tcgatccttc
    15121 ctctttaggt ttgttccttc ataagacttt tcagtttgtt caaatcattt tttaagttct
    15181 tcttattcat atcgtttttt ttcagtcttt gctcgacctt ttcaagttcc cagaatattt
    15241 ttttatcagt cgaaacaaaa actttatagt cgggatattt tttttctaag tcggatttta
    15301 ctgacttctc gatactcttt aatcgaaatc gatcaaaatt ctcaacttta atcgctgcca
    15361 taagctcttt atcagtattc acagctttta cgtctgtaat atcttccttg gcaattatct
    15421 tttctttcgc atgattggca acggattgat caattggctt acttgtatgt acttgcgaaa
    15481 taccaaaagt actattacct tgaataaatt cattttgatt accattacat cctgatgcga
    15541 aaccaatgac cattataata aaaagtaggt ttttcaatgt ggttatttta tctttcaaaa
    15601 aaatcacctc catgtttttc cattatttga acagctgaaa aaggttggtt aagaggccaa
    15661 ccttttttcg ccttactaat tactgttgtt tgtattgagg ttcttcttgt tcgatttgtt
    15721 gaacacgtgg ttcaatgctg tctacaacgg attgggtttg cttagctgca tcttggtaaa
    15781 gttgcttagc ttgttgatta tctgtactaa gagcaaatgt ttcaaaactt gcttgagcac
    15841 ttttcaatcc tgctagagct gttttaacgt catttattac tgtcatgata atttcctcct
    15901 tcttgaattt ttttttactc ttttattttg ctttatggag aattttttat tcaatgattt
    15961 ttgggaaatt taaatctaaa ttatttttga cgtatagctc cattttttcg ataataaccc
    16021 cttttccata tccccatcat ttcttctatt tctcgttgac agcaatagct cttataactt
    16081 ttcatttttt cttttctcaa cttcaatttc ttttacaccc ctacctttat aaaataagat
    16141 gattgtattt cctgaaagga ctaatatttt tcccattttt cggatattgt cccaaagttt
    16201 taagagtttc tccctcttaa tcatcctatt tatgggtatt taacattgaa aatgtaataa
    16261 caaagataaa cgcatgcatt tgtcgccgta ttaaggtttg tctaatacat aaaaaggaac
    16321 tgttttgtta ttaaacatca aatttttcat acattttaga aggtgaaaaa atgacaacaa
    16381 aacaaaaaag gaaatccttt caacgtttaa cgttaaaacc aaaaaaggac attgaagaaa
    16441 taaaacttgg gattaaactg ggagaaaaaa aggaaaccaa aaatccgaga ttgggcgaaa
    16501 gagatgtata gctatatttg atggggatta atacagaatt acaggtaggt gacattgtca
    16561 aattaaaagt tgaagatgtg aaagggaaaa attcttttat attctggaag gcaagacaac
    16621 aaaaaacaga aagtaaatat tagtatgcta tctaatagaa ttgataaaaa aattggatac
    16681 ataattgttt caaactggta gagaccatat gtatgagcag caattaatgt tccatatttt
    16741 tcgtgggtca ggcaaactct tgttcatcta gacagtaggc tgattgatta ttgatgcttc
    16801 tttcttaaca aaacacctaa gtgattctct gtgcatatac tgtatcatta ctacaggatt
    16861 atgattaaat acaactcaat ccatacataa aataatcaag gagaggttaa ttttgaaaat
    16921 tccaaagaca gccaaagtta gtatcccctt tccatccgta tgggggattg atgcttctat
    16981 tgcggggaga tccattatta gaggtatact taccattgat tccattgtag acaacaaagt
    17041 agtaggtaca gttaattttc gtggtatacc tattccgatt aatgggtatt gggacgaaag
    17101 cgctaaacaa ataagtttcg attcaccata tgcctccttt tttggcaact tgacaataat
    17161 tgatgagacc gctataagca ttcggcattt cattttaagt ggacggttta taatgaaacc
    17221 tccctctttg ctggctggtg aatacggaaa ttggattgct acaaccttta caacccgttt
    17281 gggacctccc atatatacta atgttttacc acctgctggt gccttttcag tctcaagtat
    17341 gctcttggga cagcaattgt tttaattaga ccatgacttt ataaaaacaa ccttcctttg
    17401 tgactaaggt tgttttttaa aagtgttctc gaaaaataca gccttgcttt aaatctgagt
    17461 ttagcgtata tctccgttaa aatgtactcg gaaccctttg atgatcgtgc ctagttagat
    17521 aaacaaatat tgatacttcc ttatagaaat agcctgcttg gttaggtacg ttgtttcaca
    17581 atccccggaa atttttaata taagtaatga atgcttattt ttttccttcc gatagctttc
    17641 tatataaaga agctctagat acatttgtaa tttcacaaat ttgatttaca gtcatatttc
    17701 cttctttata tagctttact gcataattca ttcctgcgtg atttttatga tatttcttta
    17761 accgtccttt aaacttccct tctttctttg cgagctcaat tccttcacgc tgacgcatac
    17821 gaataaggtc tcgctctaat tggttaacac cagccattac cgtaattaag aattggctat
    17881 atggattatc ttctgataaa tctagccatg tatccttaag tgattttaag cttgcctttt
    17941 tatttcgtat taaatcaatc aattcaaata aatcttgcgt acttcgagtg atccgagtta
    18001 aatctgtaac ataaataatg tcaccttcct gtaaatcctc taacattttt tgaagttgtt
    18061 cacgatcttt tgtggctcct gaaatttttt cttcataaat aatatccatt ccaatttcgt
    18121 tcaattgccg aaattgcctt gaaggatttt ggctagtcga actgacgcgt acataaccga
    18181 ttttctgcaa aatttcacct cgtttttgag acaagtctta tgagacactc ttaactatga
    18241 ttttatcagt ctactatact tgtatcaata gagtacactc tattgatata taattgaact
    18301 aattaactga ataattatgg aaatgggatg atactgaatg aaaattgcga gaggtagaga
    18361 attgcttaca ctggaacaga ggcaggattt tatgcaaatc cctgaagatg aatggatatt
    18421 ggggacctac ttcacttttt ccaaacggga tttagaaata gttaataagc gaaggagaga
    18481 agaaaaccgt ttagggtttg ctgttcaatt agctgttctt cggtatcccg gttggccata
    18541 cactcatatc aaaagcatcc cggaatcagt catacattat atatcgaaac aaatcggtgc
    18601 cactccatct tcgattagtc tttatcctca aagagaaaat acactttggg atcatttgaa
    18661 agaacttcga agtgaatacg actttgtaac ttttactcta agagaatatc gaatagcatt
    18721 taagcatctt catcaattag cttttgaaaa tggcgatgcc atacatctac tacatgaatg
    18781 tatagatttt ctaagaaaaa acaaaatcat actgcctgct attactacac ttgaaagaat
    18841 ggtgtgggag gcaagggcaa tggctgaaaa gaaactgttt aatactgtta gtcaatctct
    18901 tacaaatgaa caaaaaggaa agcttgaaga gatcattact tcgcagcatc catccgaatc
    18961 caataaaacg atattgggtt ggttaaagga accgccgggt catccttcac ccgaaacatt
    19021 tctaaaagta atagaacgac tcgaatacat acgaggaatg gaattagaaa cggtacaaat
    19081 tagtcatttg catcgcaatc gcctgtttca actatctcgc ttaggctcaa gatatgagcc
    19141 atatgcattc cgtgactttc aagaaaataa gcgatattcg atattaaccg tctatttatt
    19201 acatcttact caagagttaa cggataaagc ttttgaaatt catgatagac aaatacttag
    19261 tctgttatca aaaggccgta aggctcaaga ggaaattcag aaacaaaacg gtaaaaagct
    19321 gaatgagaaa gttatacact ttacgaacat cggacaagct ttaatcaaag caaaaaagga
    19381 aaaattagac gtttttgaga ttttagaatc cgttatcgaa tggaattctt ttgtctcttc
    19441 ggtcgaagaa gctcaggagc ttgcacgccc tgacgactat gattatttag acttactgca
    19501 aaaacgattt tattcactta gaaaatatac gccaacgcta ttaagggtat tggaatttca
    19561 ttctacaaaa gcaaatgagc cacttttaca agctgttgag attatccgtg gaatgaacga
    19621 atccggaaag cgaaaagtgc ctgataactc acctgtggat tttatttcaa aacgttggaa
    19681 aaagcattta tacgaggatg atggtacaac aatcaatcgt cattactatg aaatggctgt
    19741 tttaacagaa cttatggagc atgttagggc aggagatgtt tccattgttg gcagcagaca
    19801 atatagagac tttgaagaat atttgttttc agaagataca tggaatcaaa cgaaggagaa
    19861 tacaagatta tcagttagtt tatcattcga ggattatatg acggagagaa ccagcagcct
    19921 taacaaaagg ttaaagtggt tagctaccaa ttccaacaag ttagacgggg tttctcttga
    19981 aaaaggaaag ctgtcaattg aacgcttaga aaaagatgtt ccagaagaag caaaaaaatt
    20041 tagcgcaagc ctgtatcaga tgctaccaag aataaaatta accgatttac tgatggatat
    20101 tgcttatata acaggatttc atgagcaatt tattcatgct tccaataatc gaaaaccgga
    20161 taaagaagaa acaattatta ttatggctgc tcttttagga atgggaatga atattggttt
    20221 aagcaaaatg gctgaagcaa cacccggact tacatataag caattggcca atgtatcaca
    20281 atggcgcatg tatgaagatg caatgaataa agcccaagcc gtattagtaa attttcatca
    20341 caaattgcaa ttgtcctcct attggggaga cggtacaaca tcctcgtccg atggtatgag
    20401 aatgcagata ggcgtttcat cgctacatgc agatgcaaac ccacattatg gaactggaaa
    20461 aggagccacc atctatcgtt ttacaagtga tcaattttct tcttattaca caaagattat
    20521 tcatactaat tcaagggatg cgattcatgt tttggatggt ttgttacacc atgagacgga
    20581 tctaaatata gtagagcatt atacagacac ggctggttac acagaccaaa tattcggact
    20641 gacccattta ttaggattta aatttgctcc aagaatacga gatttatcag actcgaaatt
    20701 atttacaata gataaggcaa gtgagtatcc aaaattagaa gtcattttac gtggacaaat
    20761 aaatacaaag gtcattaaag agaattatga ggatgttttg cgattagctc attctataag
    20821 ggaaggaaca gtttcagcat cccttattat ggggaaatta ggttcttatt caagacaaaa
    20881 cagcttggct acagccttac gtgagatggg ccgaatagaa aaaacgatct ttattttgaa
    20941 ttatatttcg gatgaatcat taagaagaaa aatacaaaaa ggattgaata aaggagaagc
    21001 catgaatgga ctggcaagag ctattttctt cggaaaacaa ggagagctta gggaacgaac
    21061 catacagcat caattgcaaa gagccagtgc cttaaacatc attatcaatg ccatcagtat
    21121 ctggaatact ttacatctaa caaaggcagt tgaatatcaa aaacggtcag gtagttttaa
    21181 tgaagaatta ttgcaccata tgtcacctct aggttgggaa catattaatt tacttggaga
    21241 ataccatttt aattcggaga aaatggtctc gttagattct ttaagaccct tgaaactttc
    21301 ttaacgttgt taaaactggg ggaatagtcg gggaaatggg cttagcgttg taaatccgca
    21361 ttttcctgac tgtaccccat gatgaagtaa acaacagtct atcttccggc gtaaaatcaa
    21421 tataattgct gtttttcaca aggcggatca cgcttcgctg ttcaatcatg acgccttttg
    21481 gcgcacctgt tgatccggac gtataaatca tgtaggccaa tgattcaggt ccgccgagcg
    21541 gttcgggatt ttccgaactc aagccggcct ttgtttgaat atcctctatg aataaacgtt
    21601 ttcctgaaag cggcagaccg tcaagtttat cagattggag aagaatatca gctttacagt
    21661 ctttaagcat ccattcagcc cgttcccgcg gcacatcgtc accgataggc aagtaggcgc
    21721 ctcccgcttt taatattccg aggattccgg aggcaagctc tgttgtgcgg ccggttagta
    21781 aggcgacaac gctttccgga ccgacgccat ttgatcggag agccgccgct attctgttag
    21841 cccgttcgtt cagctcacgg tatgtcaaga tttgtccatc atatacaact gcccgggcat
    21901 cgggggtttc ttttgcctgc cgctcaaata aacggctgat ggtttcgtgt cttgggtaat
    21961 cgcttttcgt ctgattaaac tgataaatga cgcgatttgt ttcagcatca tccagtacgt
    22021 gaatgtcacc aagcggtatc gcttggtttt caattacttt tgtaagaata cgggtaaaat
    22081 aagaaagcca tttttcaatt gtctgttttt gatagatatc tgtattgaat tcaaaatcaa
    22141 agctgatgga accgtcagac ccttctgacg cgtaaagcgt ggcatcaaac tttgcggttt
    22201 tatgacttgt atccgcagct tgagccaaat gcagcttatt taacaccagg gattcacgct
    22261 ccatattttg gagcacaaac atcacatcaa acagcggatt gcggcttgtg tcccgctgca
    22321 cgccaagccg ttccactagc tcttcaaacg gatagtcctg atgttcatac gcctcaagcg
    22381 cggcctggcg gacttccgcc aaataatcag taaaccgttt gcctcctttc ggctccgttc
    22441 tgatggcgag cgtgttgacg aacatgccga gaatcggttc aaggtctttg tgcggacgcc
    22501 cggcaatcgg cgagccgacg atgatgtctt cctgtccgct caatctcgcg agcagcgtat
    22561 tgtacgcggc gagaa
//
