LOCUS       NZ_PVRL01000015        40591 bp    DNA     linear   CON 21-MAY-2024
DEFINITION  Bacillus thuringiensis strain NMTD81
            NODE_15_length_133085_cov_23.7659, whole genome shotgun sequence.
ACCESSION   NZ_PVRL01000015
VERSION     NZ_PVRL01000015.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis
  ORGANISM  Bacillus thuringiensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 133085)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., W,H. and Gao,X.
  TITLE     Genotypic and phenotypic analysis of antagonistic Bacillus spp.
            isolated from rhizosphere soil of plants in Tibet
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 133085)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., W,H. and Gao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) UG, NordReet, Marienstr. 27a, Greifswald
            17489, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. A5-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 14.5x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002998815.1-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 01:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,177
            CDSs (total)                      :: 6,068
            Genes (coding)                    :: 5,840
            CDSs (with protein)               :: 5,840
            Genes (RNA)                       :: 109
            rRNAs                             :: 11, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 1 (5S, 23S)
            partial rRNAs                     :: 6, 5 (16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 228
            CDSs (without protein)            :: 228
            Pseudo Genes (ambiguous residues) :: 0 of 228
            Pseudo Genes (frameshifted)       :: 100 of 228
            Pseudo Genes (incomplete)         :: 142 of 228
            Pseudo Genes (internal stop)      :: 67 of 228
            Pseudo Genes (multiple problems)  :: 63 of 228
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:59:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 40591
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVRL01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..40591
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..40591
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..40591
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[17009:20591](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(17010..20591)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     gene            <1..531
                     /locus_tag="C6351_RS24870"
                     /old_locus_tag="C6351_24880"
     CDS             <1..531
                     /GO_component="GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161202.1"
                     /locus_tag="C6351_RS24870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24880"
                     /product="LPXTG cell wall anchor domain-containing protein"
                     /protein_id="WP_142399151.1"
                     /transl_table=11
                     /translation="GGNGSGGNGSGGSSSGDNGSGGNGSGGNGSGGNGSGGNGSGGSGS
                     GDNGSGGNGSGGNGSGGNGSGGNGSGDNGSGGNGSGGNGSGGNGSGGNGSKGGNRVKGD
                     SSSQGGNGSQGGNRVKGDSSGNGSQGGNVKDNAKKQGDKLPNTATHYPASILMGLSTFL
                     IGMLLFIRRKNAK"
     gene            complement(646..2076)
                     /gene="proS"
                     /locus_tag="C6351_RS24875"
                     /old_locus_tag="C6351_24885"
     CDS             complement(646..2076)
                     /EC_number="6.1.1.15"
                     /GO_function="GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040954.1"
                     /locus_tag="C6351_RS24875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24885"
                     /product="proline--tRNA ligase"
                     /protein_id="WP_001040982.1"
                     /transl_table=11
                     /translation="MAKEQVQAITKMEEDFAQWYTDIVKKAELVDYSSVKGCMILRPYG
                     YALWENMQKVMDEKLKETGHENVYMPMFIPESLLQKEKDHVEGFAPEVAWVTHGGDEKL
                     AERLCVRPTSETLFCEHFSKIVQSYNDLPKLYNQWCSVVRWEKTTRPFLRTTEFLWQEG
                     HTIHETAEESQAETLNILNLYASFCEDYLAIPVIKGQKTEKEKFAGAKATYTIESLMHD
                     GKALQTGTSHNFGTNFSEAFDIKFLDRNGKWQYVHQTSWGVSTRMIGGLIMVHSDNNGL
                     VMPPKVAPVQVVIVPIAQHKEGVLAKATELQGHIQKVARVKIDASNKTPGWKFNEYEMK
                     GIPIRLEVGPKDIEKNQVVLVRRDTKEKEFISMDQLEERIPALLEEIHDSLFNKAKVFR
                     DENTYSATNFEEMKQVADEKQGFIKAMWCGELACEEKLKEEVGVSSRCMPFEQEHLADE
                     CICCGKEAKQMVYWGKAY"
     misc_binding    complement(2124..2330)
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     gene            complement(2424..2717)
                     /locus_tag="C6351_RS24880"
                     /old_locus_tag="C6351_24890"
     CDS             complement(2424..2717)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000383847.1"
                     /locus_tag="C6351_RS24880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24890"
                     /product="YesK-like family protein"
                     /protein_id="WP_000383852.1"
                     /transl_table=11
                     /translation="MDWLDGFGIFYIIGGITIILVFAISYLLKKRFPDKQFDIIFALSL
                     ILLCLASFPVTMMVIGGWEGMGYGFIGFFVLLGTLIGMIAHQLVKISRKSYV"
     misc_feature    2765..2779
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.78"
                     /tool="antismash"
     gene            2872..4185
                     /locus_tag="C6351_RS24885"
                     /old_locus_tag="C6351_24895"
     CDS             2872..4185
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017673773.1"
                     /locus_tag="C6351_RS24885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24895"
                     /product="ectonucleotide pyrophosphatase/phosphodiesterase"
                     /protein_id="WP_106082258.1"
                     /transl_table=11
                     /translation="MDKALTNHVIILSFDCLSALDFPILQKLPHFQSLIKKGTVVEKVE
                     PIYPSVTYPSHSTIVTGNYPNKHGVVSNTLLQPGRESPDWHWYRKSIKGTTLYDEARKA
                     NLTTAALLWPVTGRANIDYNLPEIFPNRPWQNQVLVSLFSGSPLYQLDLNRRFGHIRNG
                     LSQPELDDFVLASAVHTIQTKKPNVMFVHFTDLDTQRHYHGFESNETIAAIHRHDERLG
                     KIIQTLKDSDLYEESTIIALGDHSALSENKSIQLNVLFHQRGLISLNKKGKLVDWKAYC
                     QSCDGSAYVYVKDKNDTDTIREVQLLLEELLQNKQNGIEFILHDEAAKDRGADGNCLFM
                     LEAQEGYYFNENYTGDFIKEITEKDVTPSKKYTFGTHGYSPTKPNYETIFIAAGKGIKS
                     GVTVPYMRLIDEGPTIARLLGLHLGETDGAIVEDLLQL"
     gene            4328..5611
                     /locus_tag="C6351_RS24890"
                     /old_locus_tag="C6351_24900"
     CDS             4328..5611
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016117108.1"
                     /locus_tag="C6351_RS24890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24900"
                     /product="MFS transporter"
                     /protein_id="WP_106082259.1"
                     /transl_table=11
                     /translation="MKKMSRQEKSWILYDWANSVYSLVITTALFPIYFKAAAKEAGLSG
                     ATSTAYWGYANSFATLLISILAPILGTVADYKGFKKRFFTFFFGLGIVFTSMLAVVPTS
                     QWYLLLGCYMLALVGFAGANIFYDAFLVDVTSEDRMDRISTRGFALGYVGSTIPFIGCI
                     ALIILSQKGTIPLSVGIASQISFAITALWWGLFTIPMLKNVEQKHYIERHPRPITMSFK
                     RLAATFKNIKEYKTVFMFLIAYFFYIDGVDTIITMSTAYGTDLGISATNLLIILFVTQI
                     VACPFALLYGKLSATFTGKKMLYVGIIIYIIICIYAYFLKTTLDFWILAMLVATSQGGI
                     QALSRSYFAKLVPKESANEFFGFYNIFGKFAAIMGPVLVGVTTQLTGKTNAGVLSIIVL
                     FIIGGFLLTRVPENNTSVTPPSPKTKTL"
     gene            complement(5681..5932)
                     /locus_tag="C6351_RS24895"
                     /old_locus_tag="C6351_24905"
     CDS             complement(5681..5932)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011732448.1"
                     /locus_tag="C6351_RS24895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24905"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_095691464.1"
                     /transl_table=11
                     /translation="MSQLYTDVVKMILQVRSNGVKNQIYELRTENNISQGALADKCKVS
                     RQTINAIENNKYDPSLALAFRLAEVLGTTVDKLFLYKQ"
     gene            complement(5989..7221)
                     /locus_tag="C6351_RS24900"
                     /old_locus_tag="C6351_24910"
     CDS             complement(5989..7221)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992541.1"
                     /locus_tag="C6351_RS24900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24910"
                     /product="MFS transporter"
                     /protein_id="WP_098437949.1"
                     /transl_table=11
                     /translation="MNALFKNRAFMLVMASDILQQFAIWIRNMALLYFIMERTNNDPVS
                     VSLLSVMEYAPIFIFSFIGGALADRWNPKRTMVAGDVLSVLSIIGIVVLLKFDYWQAIF
                     FATLISAIVGQFSQPSSSRIFKRYVKEEEVANAIAFNQTLQSLFMIFGPVVGSIVYTQL
                     GLFTSLYSLIILFLLSAIILSFLPKWVEKEQVARDSLKNDIKEGWKYVLHTKNLRMITI
                     TFTIMGLAVGLTNPLEVFLVIERLGMEKEAVQYLAAADGIGMLIGGIVAAVFASKVNPK
                     KMFVFGMSILAMSFLVEGLSTSFWITSFMRFGTGICLACVNIVVGTLMIQLVPENMVGR
                     VNGTILPLFMGAMLIGTSLAGGLKELTSLVIVFCIAMALVLLAIGPVLRMQIKKEDVVN
                     KEKLTNSLASK"
     misc_feature    complement(7214..7225)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 20.11"
                     /tool="antismash"
     gene            complement(7288..7869)
                     /locus_tag="C6351_RS24905"
                     /old_locus_tag="C6351_24915"
     CDS             complement(7288..7869)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001254438.1"
                     /locus_tag="C6351_RS24905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24915"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_001254432.1"
                     /transl_table=11
                     /translation="MRRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIY
                     YHFKSKEDLFLFVVKQHTYDWLEKWNEKEKLYSTSTEKLYGLAEYHVEDIQQPISNAIE
                     EFSMSQVVSKEILDELLALTRESYVMFEKLIEAGIQSGEFREDNTRDLMYIVNGLLSGL
                     GVLYYELDYKELKRIYKKAIDVLLKGMAAE"
     gene            complement(7950..8093)
                     /locus_tag="C6351_RS24910"
                     /old_locus_tag="C6351_24920"
     CDS             complement(7950..8093)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817979.1"
                     /locus_tag="C6351_RS24910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24920"
                     /product="hypothetical protein"
                     /protein_id="WP_000817987.1"
                     /transl_table=11
                     /translation="MKREPRVKNKGKVVLFLLAAGGVFLVKLTFKFGTIHMIRTWFEST
                     FS"
     misc_feature    complement(8123..8136)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.13"
                     /tool="antismash"
     misc_feature    8127..8140
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 22.91"
                     /tool="antismash"
     misc_feature    complement(8168..8181)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.13"
                     /tool="antismash"
     misc_feature    8172..8185
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 22.91"
                     /tool="antismash"
     gene            complement(8219..8461)
                     /locus_tag="C6351_RS24915"
                     /old_locus_tag="C6351_24925"
     CDS             complement(8219..8461)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394370.1"
                     /locus_tag="C6351_RS24915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24925"
                     /product="hypothetical protein"
                     /protein_id="WP_000394363.1"
                     /transl_table=11
                     /translation="MEFIIVILLFVVVGIIVTAVRSNKKKVNLTKQNNIHNSSNSSSPL
                     FFFAGSDNDSSHDGGSHDCGGSFGGDSGGSCGGGD"
     gene            complement(8475..8789)
                     /locus_tag="C6351_RS24920"
                     /old_locus_tag="C6351_24930"
     CDS             complement(8475..8789)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713043.1"
                     /locus_tag="C6351_RS24920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24930"
                     /product="thioredoxin family protein"
                     /protein_id="WP_016078590.1"
                     /transl_table=11
                     /translation="MHKFKTIEELATYIEEQQLVLLFIKTENCGVCDVMLRKVNYVLEN
                     YDYVEKIEILLQDMQEIAGRYAVFTGPTVLLFYNGKEILRESRFISLKNLERTIQLFEE
                     "
     gene            complement(8800..9171)
                     /locus_tag="C6351_RS24925"
                     /old_locus_tag="C6351_24935"
     CDS             complement(8800..9171)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002010200.1"
                     /locus_tag="C6351_RS24925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24935"
                     /product="DUF1992 domain-containing protein"
                     /protein_id="WP_000382382.1"
                     /transl_table=11
                     /translation="MDVFLNIAEEKIRQAIRNGDLDYLPGKGKPLQLEDLSMVPPELRM
                     SYKILKNAGMIPSEMELQKDILKIEDLIACCYDEEERKKLREELTAKTLRFQQVMEKRR
                     IKDSSAFRMYQDRVFHKLR"
     gene            9543..11567
                     /locus_tag="C6351_RS24935"
                     /old_locus_tag="C6351_24945"
     CDS             9543..11567
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257491.1"
                     /locus_tag="C6351_RS24935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24945"
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="WP_106082260.1"
                     /transl_table=11
                     /translation="MRSQKFTLLLLSLLLFLPLFLTNFITPNLALADSPKQSQKIVGYF
                     PSWGVYGRNYQVADIDASKLTHLNYAFADICWNGKHGNPSTHPDNPNKQTWNCKESGVP
                     LQNKEVPNGTLVLGEPWADVTKSYPGSGTTWEDCDKYARCGNFGELKRLKAKYPHLKTI
                     ISVGGWTWSNRFSDMAADEKTRKVFAESTVSFLRAYGFDGVDLDWEYPGVETIPGGSYR
                     PEDKQNFTLLLQDVRNALNKAGAEDGKQYLLTIASGASQRYADHTELKKISQILDWINI
                     MTYDFHGGWEATSNHNAALYKDPNDPAANTNFYVDGAIDVYTNEGVPVDKLVLGVPFYG
                     RGWKSCGKENNGQYQPCKPGSDGKLASKGTWDDYSTGDTGVYDYGDLAANYVNKNGFVR
                     YWNDTAKVPYLYNATTGTFISYDDNESMKYKTDYIKTKGLSGAMFWELSGDCRTSPKYS
                     CSGPKLLDTLVKELLGGPINQKDTEPPTNVKNIIVTNKTSSSVQLSWTASTDNVGVTEY
                     EITAGEEKWSATTNSITIKNLKPNTEYTFSVIAKDASGNKSQPTALTVKTDEANTTPPD
                     GNGTATFSVTSNWGSGYNFSIIIKNNGTIPIKNWKLEFDYSGNLTQVWDSKISSKTNNH
                     YVITNAGWNGEIPPGGSITIGGAGTGNPAELLNAVISEN"
     gene            complement(12008..13552)
                     /locus_tag="C6351_RS24940"
                     /old_locus_tag="C6351_24950"
     CDS             complement(12008..13552)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716351.1"
                     /locus_tag="C6351_RS24940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24950"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_106082261.1"
                     /transl_table=11
                     /translation="MSILTVENLSHSYGEKTILYNACFRLLKGEHVGLVGKNGIGKSTL
                     LRILTGELIHDDGNIEWFPHVKVGFLQQHIDLQEGITIEGYLQSAFSNLYAIEYEMLKI
                     AEEMAEVVEVEKLLVRYGELQTILENSNFYQIHTEIEEVAIGLGLFEIGLEKDVLKLSG
                     GQRTKLLLGKLLLEKADVLLLDEPTNYLDTAHIEWLQSYLKLYEKAYIIISHDEVFLNN
                     ITNVIYHLEERKVKRYVGDYEKFLQSYQLQRKQLQSAYAKQQKEIAQLETFIQKNKIRK
                     AKQAKSREKVLEKMQRVEKVKNVPRSRFVFTVYNEPVSSILQAEKLRVGYSDSLFPELN
                     LQVKKGEKIAIVGHNGIGKTTMLKTLLDQIKPLSGSNFVGERVNPAYFAQEEFASEITP
                     LEKVWAERPDMTKKEVRQALAKCGLKEEHVLKPIHLLSGGEQTKVRLCELIATKSNVLI
                     LDEPTNHLDVETKMALKEALQQYKGTVLIVSHEPSFYESWITKVWNIEEWNAEQYE"
     gene            complement(13948..14697)
                     /locus_tag="C6351_RS24945"
                     /old_locus_tag="C6351_24955"
     CDS             complement(13948..14697)
                     /EC_number="7.6.2.7"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000016061.1"
                     /locus_tag="C6351_RS24945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24955"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000016082.1"
                     /transl_table=11
                     /translation="MSGLQIKNIVKSFDGKNVLENISASIQEGEFVSFVGPSGCGKSTL
                     LNMIANVEKPTSGNVTYKDKQVQEQDVVSYMPQQDLLLPWRSALQNIVLPLEIEGKPKK
                     QRLTEGMEALKQFELDEYADHYPDELSGGMRQRISFLRTYLCEKPIMLLDEPFGKLDAF
                     TKMEVHSWLLNSWHQEKQTIVMVTHDLDEAILLSDRVFILSQRPASIVGEVQVKLPRLR
                     TMDMLTSLELKKDKEEILSVLAPYMKK"
     gene            complement(14694..15692)
                     /locus_tag="C6351_RS24950"
                     /old_locus_tag="C6351_24960"
     CDS             complement(14694..15692)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002091223.1"
                     /locus_tag="C6351_RS24950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24960"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_106082262.1"
                     /transl_table=11
                     /translation="MKKGLKVMLAALVAVGVAGCNPAKKEESKSKDQKVKVVLDWFPNT
                     NHTGLYVAQTKGYYKKQGLDVEIIQPGDNVTAEQMIASGKADFAISAQENVTLARVEGI
                     PVVSVGAIIQHNTSAFASLKKDNMTSPKDFEGKRYGGWGGPAEEATLKTIMDKHQADFN
                     KVEKIILGQTDFFKSIGRDADFEWIYYGWDGIEAKRQGKELNTIMVKDLDPALDFYSPV
                     IITSEKHTKQDKDFVKKFMSATTEGYNFAIKEPKEAADILIKAVPDVNKDLVQESQKWL
                     STKYQDDAKAWGVQKEEIWTNYMNFLYDNKVIKKKIDVKDAFTNEFLPSEK"
     gene            complement(15689..16462)
                     /locus_tag="C6351_RS24955"
                     /old_locus_tag="C6351_24965"
     CDS             complement(15689..16462)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016107454.1"
                     /locus_tag="C6351_RS24955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24965"
                     /product="ABC transporter permease"
                     /protein_id="WP_001057166.1"
                     /transl_table=11
                     /translation="MNMQNQKQSKLITTIWLILLIAIWEGSVSLFKIEPWILPKPSAIV
                     QELIGMKDLLLPNTMQTLQEVIIGLFFAILLGTSIAIIMDVIPLFRILINPLLVISQTI
                     PIVVLAPLFIIWFGYGMLPKVMVVILVCFFPIALSILEGFQTVDKNMLKLLQTMKATKW
                     QVYQKVKFPAVLPYFFSGLKIAVTYSVMGAIIGEWLGASEGLGVMLTRATKSFLTARVF
                     GVAAIIVMVTLCLYFIVEFMARITAPWIYRKDGRK"
     gene            complement(16434..16754)
                     /locus_tag="C6351_RS24960"
                     /old_locus_tag="C6351_24970"
     CDS             complement(16434..16754)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000082896.1"
                     /locus_tag="C6351_RS24960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24970"
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="WP_000082906.1"
                     /transl_table=11
                     /translation="MSQQVTMSFSVVPQAKTKDVYSVVDKAIEVVQQSGVRYEVGAMET
                     TLEGELDVLLDVVKRAQQACVDAGAEEVITSIKIHYRPSTGVTIDEKVWKYRDEYAKPE
                     AI"
     misc_feature    16730..16742
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    16834..16850
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 24.98"
                     /tool="antismash"
     regulatory      complement(16856..16957)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(17010..20591)
                     /locus_tag="C6351_RS24965"
                     /old_locus_tag="C6351_24975"
     CDS             complement(17010..20591)
                     /NRPS_PKS="Domain: AMP-binding (225-621). E-value:
                     1.1e-107. Score: 352.0. Matches aSDomain:
                     nrpspksdomains_C6351_RS24965_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (730-794). E-value: 4.2e-19. Score:
                     60.5. Matches aSDomain: nrpspksdomains_C6351_RS24965_PCP.1"
                     /NRPS_PKS="Domain: NAD_binding_4 (833-1071). E-value:
                     1.4e-53. Score: 173.5. Matches aSDomain:
                     nrpspksdomains_C6351_RS24965_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761477.1"
                     /locus_tag="C6351_RS24965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24975"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_106082263.1"
                     /sec_met_domain="AMP-binding (E-value: 4.8e-115, bitscore:
                     377.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.9e-10, bitscore:
                     32.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.7e-53, bitscore:
                     173.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLAISYNEMVKEFLGKVEGSIKIPKDVQGTEFGVKRKTELFPNL
                     THIVDLIGATATWLYHISKEKHIVVLYHVRGSLFPITIEISNFLSYESLNLQIEEQLEQ
                     IKEMNEEEIEEFQNGNTLYEMSPIIIGETYYELQDTNTLQFVFSKNMQSVEIIFNSVNW
                     KETTITRYAQQIQGVLINTLQNNNNYINDFNVITEAEMALYSQVNDTTAVYPEKSIVDM
                     FYNTVTQFPNRIALSSREGTLTYEELNKKSNQIAHMLIKNGVQLGDYVGIFMKRSIDTV
                     VSMVAILKAGAAYVPIDPDYPESRIQYIIQDSQAKVILMKETPITCDGVQTVSMYDSET
                     CEDIDVKLSIHCDDVAYMIYTSGSTGNPKGTMLAHRGVVNLYTWMQKQYELTEEDVFAQ
                     FPSFSFDASVWESFASLFCGGNLYVLLEEERLSVEAFAHAIYKVKATSILALATIFVRQ
                     IATYLAEEDIYKLASLKRIAIGGEMLPVEVIKLWRERIRTNVEIHNVYGPTECTVVTTT
                     YKIPSQLNEDVASIPIGKPCSNYQVMILDENMNLCPIGVPGELYIDSVGLAKGYFNKPN
                     KTIEAFIPNPFNPIVNIYKTGDIVKLLEDGNIEFLHRKDDQVKIRGHRIELGEIQSKIS
                     QNHNIKENAVFAKKSKEGSQYLIAFYTTLNKKEIPELVYQLQEQLPDYMVPSKLIYINE
                     LPLTPNKKIDVKKLAQLEEKYEPVRLQEYVAPSNKAEKQIANAWAEVLGISKVGVHDDF
                     FTIGGHSLKVLRVLTLLKEDFSHLTIQDFFKERTIYGLARIEREVKVEKEEVFREYKVI
                     HEPDTITYANVLEETQISNVFLTGATGYLGSHILYELLRDTSATIYCLVRPTKDVQQRI
                     IDTLTAYFNDICEEWLQRIQAVAGDLGEEYLGMSEEEFMFISSKMDTIIHCGADVRHFG
                     DVKQFENINVQGTSRMLALVEKDATFHFISTIGIPLELAVDQWDTYMKTGDFNYSVDLE
                     NVYSNSKLQAENIVREAMKNGLRGNIYRAGNLACHSETGSFQQNIEGNAFYRLIKTMLL
                     IGKAPNVKWKVDFTPIDFASKSIVTYVQDSQIDGETLHICHPHQIEFEQFIQLIGECGY
                     NLELVTLSEYENAGLELAKGNEVIAELIASQVAGDGAQQSEIVMGTRRTNEWIKKKELK
                     VPAINKEFIQQLLAHGEKVGYFPKIMK"
     aSDomain        complement(17379..18092)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS24965_NAD_binding_4.1"
                     /evalue="1.40E-53"
                     /label="C6351_RS24965_NAD_binding_4.1"
                     /locus_tag="C6351_RS24965"
                     /protein_end="1071"
                     /protein_start="833"
                     /score="173.5"
                     /tool="antismash"
                     /translation="LTGATGYLGSHILYELLRDTSATIYCLVRPTKDVQQRIIDTLTAY
                     FNDICEEWLQRIQAVAGDLGEEYLGMSEEEFMFISSKMDTIIHCGADVRHFGDVKQFEN
                     INVQGTSRMLALVEKDATFHFISTIGIPLELAVDQWDTYMKTGDFNYSVDLENVYSNSK
                     LQAENIVREAMKNGLRGNIYRAGNLACHSETGSFQQNIEGNAFYRLIKTMLLIGKAPNV
                     KWKVDFTPIDFASKSI"
     aSModule        complement(17379..19916)
                     /complete
                     /domains="nrpspksdomains_C6351_RS24965_AMP-binding.1"
                     /domains="nrpspksdomains_C6351_RS24965_PCP.1"
                     /domains="nrpspksdomains_C6351_RS24965_NAD_binding_4.1"
                     /locus_tags="C6351_RS24965"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(18210..18401)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS24965_PCP.1"
                     /evalue="4.20E-19"
                     /label="C6351_RS24965_PCP.1"
                     /locus_tag="C6351_RS24965"
                     /protein_end="794"
                     /protein_start="730"
                     /score="60.5"
                     /tool="antismash"
                     /translation="EKQIANAWAEVLGISKVGVHDDFFTIGGHSLKVLRVLTLLKEDFS
                     HLTIQDFFKERTIYGLARI"
     CDS_motif       complement(18699..18764)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS24965_0005"
                     /evalue="1.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="C6351_RS24965"
                     /protein_end="631"
                     /protein_start="609"
                     /score="36.0"
                     /tool="antismash"
                     /translation="FLHRKDDQVKIRGHRIELGEIQ"
     aSDomain        complement(18729..19916)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS24965_AMP-binding.1"
                     /evalue="1.10E-107"
                     /label="C6351_RS24965_AMP-binding.1"
                     /locus_tag="C6351_RS24965"
                     /protein_end="621"
                     /protein_start="225"
                     /score="352.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="TVTQFPNRIALSSREGTLTYEELNKKSNQIAHMLIKNGVQLGDYV
                     GIFMKRSIDTVVSMVAILKAGAAYVPIDPDYPESRIQYIIQDSQAKVILMKETPITCDG
                     VQTVSMYDSETCEDIDVKLSIHCDDVAYMIYTSGSTGNPKGTMLAHRGVVNLYTWMQKQ
                     YELTEEDVFAQFPSFSFDASVWESFASLFCGGNLYVLLEEERLSVEAFAHAIYKVKATS
                     ILALATIFVRQIATYLAEEDIYKLASLKRIAIGGEMLPVEVIKLWRERIRTNVEIHNVY
                     GPTECTVVTTTYKIPSQLNEDVASIPIGKPCSNYQVMILDENMNLCPIGVPGELYIDSV
                     GLAKGYFNKPNKTIEAFIPNPFNPIVNIYKTGDIVKLLEDGNIEFLHRKDDQVKIR"
     CDS_motif       complement(18846..18935)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS24965_0004"
                     /evalue="4.10E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="C6351_RS24965"
                     /protein_end="582"
                     /protein_start="552"
                     /score="35.1"
                     /tool="antismash"
                     /translation="PIGVPGELYIDSVGLAKGYFNKPNKTIEAF"
     CDS_motif       complement(19047..19076)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS24965_0003"
                     /evalue="3.90E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="C6351_RS24965"
                     /protein_end="515"
                     /protein_start="505"
                     /score="9.9"
                     /tool="antismash"
                     /translation="YGPTECTVVT"
     CDS_motif       complement(19467..19526)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS24965_0002"
                     /evalue="5.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="C6351_RS24965"
                     /protein_end="375"
                     /protein_start="355"
                     /score="28.2"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGNPKGTMLAH"
     CDS_motif       complement(19698..19736)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS24965_0001"
                     /evalue="6.60E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="C6351_RS24965"
                     /protein_end="298"
                     /protein_start="285"
                     /score="19.2"
                     /tool="antismash"
                     /translation="AILKAGAAYVPID"
     misc_feature    20635..20650
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.89"
                     /tool="antismash"
     gene            complement(20727..22469)
                     /locus_tag="C6351_RS24970"
                     /old_locus_tag="C6351_24980"
     CDS             complement(20727..22469)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016121779.1"
                     /locus_tag="C6351_RS24970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24980"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_000761081.1"
                     /transl_table=11
                     /translation="MKKYWHKLSFLQKNVLLTVLVILTLVGSMGALSFNMFQNSMMSLF
                     ERQSIETGEIVLKKLDVELVRDMAKDPTAEKVKKEKLTEKLDEVSKELKSVGQTYVTGA
                     KPNEKRELQLVGLTTELTNAFPIKPGDYYEQPAHWMKAYDKVIDTKKAQMTEVYEDEIG
                     SWVTILEPITDGENNIVAIIAADLDASIVPITKEKFMIQGLLFIIISLAIATITQFFIV
                     RHSLAPLKDLREGLRKIGEGDLSIKLKERPDDIGIINVYFNNTIEKFKGIIDKVRQTAE
                     QVSSSSQELSASTEENSMAVQEIASSIEGLRVGAQSQKTSVQQCLGIVHGMEDKVEEIT
                     GAAKQVAVASEGMEQHSIEGNEVIGQIINQMSLIQNAVQDLSSIIYSLETRSKEISDIV
                     TVITGISNQTNLLALNASIEASRAGAAGRGFAVVADEVRKLAEQTEASAKDIAKLIGET
                     QAETEDAVVSMQKGSKEVETGISLVQSSGDFFEKISKSAQSVTDQVKAVSGNSSDILQN
                     SQNIVQVVNELSHIANTYANSSSNVEESMKEQEISVQDIAELATSLSWLSQELQELIGE
                     FKSE"
     misc_feature    complement(22582..22596)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 17.11"
                     /tool="antismash"
     regulatory      complement(22604..22688)
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            22970..24283
                     /locus_tag="C6351_RS24975"
                     /old_locus_tag="C6351_24985"
     CDS             22970..24283
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015556 - C4-dicarboxylate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498692.1"
                     /locus_tag="C6351_RS24975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24985"
                     /product="anaerobic C4-dicarboxylate transporter"
                     /protein_id="WP_000498704.1"
                     /transl_table=11
                     /translation="MFWLQFLTLLLCIFIGARLGGVGLGVMGGVGMAILVFVFHLQPTA
                     PPIDVMLMILAVITAAGALQAAGGMDYLVHLAEKALRKNPKRITFFAPIVTYLFTLCAG
                     TGHVAYSVLPVIAEVSRESGIRPERPMSIAVIASQQAITASPISAATVALLAMLADYKI
                     TLLDILKVSIPSTFIACMLAAFVASKMGKELNEDPEYLKRLKEGMIPKLEEKKEFVGVK
                     GAKLSVILFLVGTFLVVLLGSFEALRPGWIVDGKLARLSMPNTIEMVMLTIAALIIIFC
                     KPNVESIVSGNVFKAGATAVVAIFGIAWMGDTFFNGNLNMIQGSIQHLVTSAPWLFAIA
                     LFILSILLYSQAATVRALMPLGLSLGIPPALLIAMFPAVNGYFFIPNYGTIVAAINFDR
                     TGTTGIGKYVLNHSFMIPGLIATFTSIGIGMLLISIMF"
     gene            complement(24400..25059)
                     /gene="thiE"
                     /locus_tag="C6351_RS24980"
                     /old_locus_tag="C6351_24990"
     CDS             complement(24400..25059)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016083676.1"
                     /locus_tag="C6351_RS24980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24990"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_139213321.1"
                     /transl_table=11
                     /translation="MMRIETKKMSNLLQVYFIMGSNNCTRDPLAVLKEALDGGVTLFQF
                     REKGEGSLIGGDRVRFAKELQTLCKEYSVPFIVNDDVELAIELDADGVHVGQDDEGITS
                     VREKMGDKIIGVSAHTIEEARFAIENGADYLGVGPIFPTSTKKDTKAVQGTKGLAYFRE
                     QGITVPIVGIGGITIENTAAVIEAGADGISVVSAISLAESAYESTRKLAEEVKRSL"
     gene            complement(25074..25883)
                     /gene="thiM"
                     /locus_tag="C6351_RS24985"
                     /old_locus_tag="C6351_24995"
     CDS             complement(25074..25883)
                     /EC_number="2.7.1.50"
                     /GO_function="GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016125363.1"
                     /locus_tag="C6351_RS24985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24995"
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="WP_106082264.1"
                     /transl_table=11
                     /translation="MNMKEISKVVDLVRESNPLVHNITNVVVTNFTANGLLALGASPVM
                     AYAKEEVAEMASIAGALVLNMGTLRPEEVEAMLLAGKSANVNNVPVLFDPVGAGATSYR
                     TEVARHIPAEIDLAIIRGNAAEIANVINEKWEIKGVDAGTGNGNVVGIARQAADELNTV
                     AVITGKEDVVTDGERTIVIRNGHPILTKVTGTGCLLTSVIGAFVAVEKDYVKATVAALT
                     FYGVASELAAAKTVEKGPGSFQIEFLNQLANTTSADIEKYGKIEELE"
     regulatory      complement(25956..26068)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(26095..26111)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.78"
                     /tool="antismash"
     gene            26278..28467
                     /gene="topB"
                     /locus_tag="C6351_RS24990"
                     /old_locus_tag="C6351_25000"
     CDS             26278..28467
                     /EC_number="5.6.2.1"
                     /codon_start=1
                     /gene="topB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140209.1"
                     /locus_tag="C6351_RS24990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_25000"
                     /product="DNA topoisomerase III"
                     /protein_id="WP_106082265.1"
                     /transl_table=11
                     /translation="MSKSVVIAEKPSVARDIARVLKCDKKGNGYLEGNKYIVTWALGHL
                     VTLADPESYDMKYKKWNLEDLPMLPKRLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVAT
                     DAGREGELVARWIIDKVKLNKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVAR
                     SEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIASREDEIKNFKAQTYYGIEAQTM
                     EKLKLTWQDTNGNSRSFNKEKIDGIVRGLDKQNATVVEIDKKQKKSFSPGLYDLTELQR
                     DANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRP
                     FAHKVLQKPIKPNKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVL
                     FPAFEYEQLTLRTKVGSETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPHIEK
                     GDTLTVKLLMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVA
                     TRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGK
                     LKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQ
                     DRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGN
                     KADKRDVQKYMKQQNKEEEPLNNPFAEALKKLKFD"
     gene            complement(28506..31367)
                     /locus_tag="C6351_RS24995"
                     /old_locus_tag="C6351_25005"
     CDS             complement(28506..31367)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810109.1"
                     /locus_tag="C6351_RS24995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_25005"
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="WP_106082266.1"
                     /transl_table=11
                     /translation="MKQIWRIYKTDLRNVAKHWAAIVIVLGLMILPSLYAWFNIKASWD
                     PYGNTKEVPIAVSNQDAGSNLRGKDINIGKEIVDSLKKNKNLGWKFVDEKQAIYGVERG
                     DYYASITIPKDFSEKIATVLDENPKKPELDYYVNEKVNAIAPKITAKGASGITEEISKN
                     FVKTANGEIFKIFNDLGIDLETNLPSIEKVKDLVFKLEAQFPEMNTLMDKALDDATRAE
                     DIVKVAQKDLPVVESVINDGQEALANLDKFFARQDQTLKNAPGTIRNDLVVAKGVMDSA
                     AVFTNFLMNPGVDLNIPDFSGMNGLPEFPARPDLSKLNNDGYKSIAQNINQTVNNVLSS
                     SRAGTAYGKSVLNGLQNGQFDPEQAKKDLNAVSNQLQARTEGISYLINVFTELQNSATT
                     DFGKSFFQGRVDRLTKLKSGMENANNGIKDIVNVIGTGQEVKKDVTDVANQKLDAANAL
                     IDQAEKDYNETFVADYKKAVSTVDQAKANANEIYDNAKADYDKAKNGLESTKSSVQKAL
                     EDVQNKGINGLEGSKEALKSLNGQFQSGIGLIDDMIPVLESTNKVLADVNSDKNLNNGI
                     AKLNKAKSSLQKGVDATNKGITLLNNGQKPTKDVIESINNAAKGGSAQLTDVLSTYDSE
                     IVPNFNTAIARTKEMSKNTTQILNDADKKLPDVKKLLEDSSKGLVDGKKKLADIKAEMP
                     ATEKKIKELADKIRDFESEEDLKDIIRLLKNDVEKQSDYFANPVNLKENKLFAMPNYGS
                     AMSPFYTVLALWVGALLMVSLLTVEVHEEGANYKSHEIYFGRLLTFLTIGLSQAFIVSM
                     GDIFLLGTYVVDKFWFVLFSLFIGGVFVCIVYSLVSIFGNVGKSMAIILLVLQVAGSGG
                     TFPIQMTPAFFQAIYPFLPFTYAISAIRETVGGMLWDIVTRDLLVLSAFVVVMIVAALL
                     LKTPINKSSEKFVENAKGSKIIH"
     misc_feature    31416..31428
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: strong, score: 25.04"
                     /tool="antismash"
     gene            complement(31672..32463)
                     /locus_tag="C6351_RS25000"
                     /old_locus_tag="C6351_25010"
     CDS             complement(31672..32463)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016121527.1"
                     /locus_tag="C6351_RS25000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_25010"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_000771989.1"
                     /transl_table=11
                     /translation="MKLLTLNCHSWQEENQIEKIQYLAKVIQEEEYDVIALQEVSQSIQ
                     AENVCGNKKEDNFGLLLLEELKALHVKDYNITWDFSHIGYDVYEEGLAIITKHNIIKED
                     TFFISENEDTTYWKTRKIVSTTIAYNGKDITFYSCHLGWWNDEEESFKGQVDRLMGRVD
                     SNKLAFLMGDFNNNARLEGEGYEYMMQKGLYDTYELAIEKDEGTTVQGEIAGWDENKHN
                     LRIDLILCNQSKKVHSSKVIFNGTNRNVISDHFGVEVQLDI"
     gene            complement(32468..34105)
                     /locus_tag="C6351_RS25005"
                     /old_locus_tag="C6351_25015"
     CDS             complement(32468..34105)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002151611.1"
                     /locus_tag="C6351_RS25005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_25015"
                     /product="PTS transporter subunit IIBC"
                     /protein_id="WP_000705560.1"
                     /transl_table=11
                     /translation="MKITSFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMSAGDVNA
                     VHTIARVMEDIGWAIITNLHILFAVAIGGSWAKDRAGGAFAALLAFVLTNRITGAIFGV
                     NAEMLADSKAKVSSVIAGDLIVKDYFTSVLGAPALNMGVFVGIITGFLGATLYNKYYNY
                     NKLPQALAFFNGKRFVPFVVILWSTVTAIVLSLLWPFIQSGLNEFGRWIAASKDSAPVV
                     APFVYGTLERLLLPFGLHHMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWITD
                     LNNLLANGDTKAYNDLLNNVVPARFKAGQVIGSTAALMGIAFAMFRNVDKEKRAKYKPM
                     FLSAALAVFLTGVTEPIEFMFMFIAPVLYVVYAITTGLAFALADLINLRVHAFGFIELI
                     TRTPMMVNAGLTRDLINFVIVSLVFFGLNFTLFNFLIKKFNLPTPGRAGNYIDNEDEAS
                     EGTGNVQDGSLATKVIDLLGGKENIADVDACMTRLRVTVKDLDVVAPEAQWKQNGALGL
                     IVKDKGVQAVYGPKADVLKSDIQDMLGA"
     gene            complement(34311..35975)
                     /locus_tag="C6351_RS25010"
                     /old_locus_tag="C6351_25020"
     CDS             complement(34311..35975)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754571.1"
                     /locus_tag="C6351_RS25010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_25020"
                     /product="alpha-glucosidase"
                     /protein_id="WP_001044700.1"
                     /sec_met_domain="Alpha-amylase (E-value: 3.5e-104,
                     bitscore: 341.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTWWKEAVAYQIYPRSFMDSNGDGIGDLQGIIAKLDYLKDLGI
                     DVIWICPMYKSPNDDNGYDISDYQDIMDEFGTMADFDALLDEVHKRDMKLIIDLVINHT
                     SDEHPWFIESRSSKDNPKRDWYIWHDGKDGAEPNNWESIFNGSAWEYDEETEQYYLHLF
                     SRKQPDLNWENKEVREVLYDTVNWWLDKGIDGFRVDAISHIKKEEGFKDMPNPKELKYV
                     PSFDKHMNVKGIQPLLEELKENTFSKYDIMTVGEANGVKIEDAELWVGEEQGKFNMVFQ
                     FEHLSLWDAEKKKDLDVVGLKKVLTKWQKGLENKGWNALYIENHDKPRIVSTWGDDKQY
                     WRESATALGAMYFFMHGTPFIYQGQEIGMTNVQLPNIEDYDDVAIKNLYREKIAEGVPH
                     QDMMEIIWASCRDNSRTPMQWNDEMNAGFTTSTPWFSMNPNYKEINVEKQKNEEKSIFN
                     FYKKMIALKKEHDVLNYGTYDLLLEDDPQIYAYTRTLQDEKVIVISNISKEEAVYNEGS
                     FALERKRLLLNNYEVAEHEEVTTIALKPYETRVYRIS"
     misc_feature    36013..36024
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.81"
                     /tool="antismash"
     misc_feature    complement(36025..36042)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 20.69"
                     /tool="antismash"
     gene            36219..37553
                     /locus_tag="C6351_RS25015"
                     /old_locus_tag="C6351_25025"
     CDS             36219..37553
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016083682.1"
                     /locus_tag="C6351_RS25015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_25025"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_000814907.1"
                     /transl_table=11
                     /translation="MKQTKLTGRIVVPTDPDYNVARMNLNLSIPKLPCIIVFCQNNKDI
                     CNALKWARERHIPFRLRSGRHSYENFSLLNRGLIIDVSEMHRITVNTEKLTATIEAGAN
                     LGTVYKELWNYGVTIPAGTSASVGIVGLALGGGIGMLSRLFGLTCDQLMEVEMVQACGK
                     FGAKPIRANEQENSNLFWACRGGGGGNFGIITSLTFRVHPVKNVSIFSITWEWEDFIAA
                     FQAWQNWAPYIDERLTSSIELFAKQRNKIEAQGEFVGSPSELHSLLSPLLETGSPSLFI
                     EEVPYIKAVEFFNGGNIPENFKRSGSYVYKPIPLKGIQLMQYFLSHAPNKDASIWHQSL
                     IGAVENISPNETAYFHRKAIIAQEYITSWKCDDEENRNIRWVKDLRESLDPYTLGDYVN
                     WPDIDIKNWQTSYYGSNFHRLRKVKTMYDPCDVFHFQQSIPPFHT"
     gene            complement(37677..38360)
                     /locus_tag="C6351_RS25020"
                     /old_locus_tag="C6351_25030"
     CDS             complement(37677..38360)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016125360.1"
                     /locus_tag="C6351_RS25020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_25030"
                     /product="hypothetical protein"
                     /protein_id="WP_000619192.1"
                     /transl_table=11
                     /translation="MIRIEYDRLVAICYSIGVLLLLKIPNDNELIGEKLFNVYKVPIHT
                     YVYMDYKVSNILIVSFILHVIAFILFLKWLGKKESSTFRKMNKIKVVGISILIVMMPFI
                     LNTILQTLNKTWYYAGKTGVEAIEYKKEDSQCRMEKNGDNIQPKCIVTLKNYRNHSQAL
                     KVVLYDNANENSKSYPVPKPVYLQKHETKQFEFQVPVSYNRGMEKDKVPNIKLHSLHEN
                     DTKYN"
     misc_feature    complement(38514..38528)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.62"
                     /tool="antismash"
     gene            complement(38517..39206)
                     /locus_tag="C6351_RS25025"
                     /old_locus_tag="C6351_25035"
     CDS             complement(38517..39206)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081904.1"
                     /locus_tag="C6351_RS25025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_25035"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_001081906.1"
                     /transl_table=11
                     /translation="MNRRNVVKDLKQFELFAHLTEKKLKGLTEFVYWRTYKKGQFLFLE
                     GDSRERIYFMLDGFVKLERVNQNGNLLYDDYVKRYSIFPYGGMFTDRGYNYTAEAMTDV
                     EVYYIPTVIFEDMVKSSRTQLMYVVQQLSSILKLNENRVQNITIPNAQDRVIQTLNYLM
                     QDLGEQSGEKIVISCPLTTIEISKISGTSRETVSSVLKQLKNDSIVTILDKKITIHNPT
                     YFEEISM"
     gene            complement(39409..40371)
                     /gene="arcC"
                     /locus_tag="C6351_RS25030"
                     /old_locus_tag="C6351_25040"
     CDS             complement(39409..40371)
                     /EC_number="2.7.2.2"
                     /GO_function="GO:0008804 - carbamate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="arcC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113957.1"
                     /locus_tag="C6351_RS25030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_25040"
                     /product="carbamate kinase"
                     /protein_id="WP_000113953.1"
                     /transl_table=11
                     /translation="MARRKIVVALGGNAIQSGEATAGAQQEALEKTAEQLVKIMENDVD
                     IVIAHGNGPQVGNILLQQKAAETEKTPAMPLDTCGAMSQGMIGYWMENAIEKALKKRNI
                     QKDVATVITRVVVDKKDEAFKNPTKPIGPFYTEEEARRLMDETKAVFKEDAGRGWRRVV
                     PSPKPVSIHEHKVINSLVEDGNIVIAVGGGGIPVIDSEEGLKGTEAVIDKDFAAQKLAE
                     LVDADTLVILTAVDHVYVNYNQPNQKKLEHVTVNQLEEYIEEQQFAAGSMLPKIEAAIN
                     FVNTNPKRKTIITSLEKVYEALEEKAGTIISKQNVCMYV"
ORIGIN
        1 ggcggcaatg gttccggcgg taacggttct ggtggcagta gctctggtga caacggttct
       61 ggtggcaatg gttctggcgg caacggctct ggtggcaacg gctctggtgg caacggctct
      121 ggtggcagtg gctctggcga caacggttct ggtggcaatg gttctggcgg caacggctct
      181 ggtggcaacg gctctggtgg caatggctct ggcgacaacg gttctggtgg caatggttct
      241 ggcggcaacg gctctggtgg caacggctct ggtggcaatg gctctaaagg cggtaatcgt
      301 gttaaaggcg atagcagttc tcaaggtggt aatggctctc agggcggtaa ccgtgttaaa
      361 ggcgatagca gtggaaacgg ctctcaaggt ggcaatgtaa aagataatgc gaaaaaacaa
      421 ggcgataagt taccgaatac ggcaacacat tatcctgcat ctattttaat ggggctttca
      481 acattcctaa ttggtatgtt actatttatt cgccgtaaaa acgcaaaata aaacacatcc
      541 ttccatctaa aaaatacatg aaataaattg taaaaactaa aaggacttta ggttgcattt
      601 tattatgcag cctaaagtcc tttttatcac ctatcagaag gattattaat acgcttttcc
      661 ccaatacacc atttgtttag cttctttacc acaacaaata cattcgtcag ctaaatgctc
      721 ttgctcaaaa ggcatacaac gtgaagatac tccaacttct tcttttagtt tctcttcaca
      781 agctaattct ccgcaccaca ttgccttaat aaatccttgc ttttcatcag ctacttgttt
      841 catctcttca aaattcgtcg cactatacgt attctcatcg cgaaatactt ttgccttatt
      901 aaataaagag tcatgaattt cctcaagtag tgctggaata cgttcttcta attgatccat
      961 tgatataaat tctttttctt tcgtatctct tcttacaagt acaacttgat tcttttcaat
     1021 atctttaggc ccaacttcta atcgaattgg aatgcccttc atttcatact cattaaattt
     1081 ccagcccggt gttttattac tagcatctat tttcacgcgt gcaacttttt gaatatgtcc
     1141 ttgtaactct gttgctttcg ctaaaactcc ttctttatgc tgagcaattg gtacgataac
     1201 aacttgcact ggagcaactt ttggtggcat tacaagtcca ttattatcgc tatgaaccat
     1261 aattagccca cctatcattc ttgttgatac accccaagat gtttggtgta catattgcca
     1321 cttaccgtta cgatctaaaa atttaatatc aaatgcttca gagaaattcg ttccaaagtt
     1381 atgggatgtt cctgtttgaa gtgctttccc atcatgcatt aagctttcaa ttgtataagt
     1441 tgcctttgct ccagcaaact tctctttttc tgttttttgt cctttaataa ctggtatcgc
     1501 taaataatcc tcacagaaag aagcatataa gtttaaaata tttaatgttt cagcctgcga
     1561 ttcttctgcc gtttcatgga ttgtatgacc ctcttgccat aaaaattcag tcgtacgaag
     1621 gaatggtcta gttgtcttct cccaacgaac tactgaacac cactgattat ataactttgg
     1681 caaatcatta taggattgca caatttttga aaagtgctca cagaataaag tttcagatgt
     1741 aggacgtaca caaagtcttt ccgctaactt ttcatccccg ccatgcgtaa cccatgctac
     1801 ttcaggagca aatccttcaa catgatcctt ctctttttgc aataaactct ctgggataaa
     1861 cattggcata tatacatttt catggccagt ttcttttaac ttctcatcca tcaccttctg
     1921 catattctcc cataaggcat aaccatacgg acgtaaaatc atgcaccctt ttacacttga
     1981 ataatcaacc agttcggctt tttttacaat atcggtatac cactgcgcaa agtcctcttc
     2041 catcttcgta atggcttgca cttgttcttt tgccatagtc agtcttcctc cttctagaaa
     2101 atacaaaaaa gcccgcgtcc ctaaataggg accgagcttt gccggcgtta ccaccctgat
     2161 tcatacacaa aaattgtata tgctctcttc ttgataacgg gaaattcccg ctgcatatgc
     2221 agaactcaaa ggcaggttcc atattgcctt tttaagaatc tttcagcctg gcggattctc
     2281 tctctgctaa aaaggttgaa catgtactag tcctttttca tcgttataat aaaataaatt
     2341 tgttgattat cataatacaa attctttttt aaaacaatag ctaattttct tattattata
     2401 tattcttttc gttttttgca gttttatacg tagctttttc gagagatttt tacaagttga
     2461 tgtgcaatca taccgatgag tgtccctagt agaacgaaga aaccaataaa tccatatccc
     2521 attccttccc acccaccaat aaccatcatt gtaacgggaa aggacgctaa gcaaagaagt
     2581 attaaactaa gtgcaaatat aatatcgaac tgtttgtctg gaaaccgttt ctttagtaaa
     2641 tatgaaatag caaatacaag gataatcgtg attccgccaa tgatgtaaaa gataccaaat
     2701 ccatctaacc aatccatagt gtttcctcct tccatagatt cccttatact taattatatg
     2761 tttatttttt ctgaaaataa ataatgaatt tccacctaaa aatatatttt tattactagg
     2821 tattaatagt aatatataag aataggtttt atataatcag gagggaactt tatggataaa
     2881 gcattaacaa accacgtcat tattttatca ttcgactgtt tatcagcttt agattttcct
     2941 atactacaaa aactacctca tttccaatct ctaataaaaa agggcacggt tgtcgaaaaa
     3001 gtagaaccaa tttatccttc tgtaacatat ccaagccact caacaatcgt aaccggtaat
     3061 taccctaaca agcacggtgt tgttagcaat acgttacttc aaccagggcg tgaatcacct
     3121 gattggcatt ggtaccgaaa atcgataaaa ggaacaacat tgtatgatga agcacgtaaa
     3181 gcaaatttaa cgacagctgc ccttctatgg cctgttactg ggagagcaaa cattgattac
     3241 aatttaccag aaattttccc caatagaccg tggcaaaatc aagtgttagt ttccttattt
     3301 agcggtagcc cactatacca attagattta aatcgtcgtt tcggccatat aagaaatggt
     3361 ttatcacaac cagagctgga tgatttcgtc ctcgcctctg ctgtacacac cattcagacg
     3421 aaaaagccta atgttatgtt cgtacatttc actgatttag acacgcaaag acattatcat
     3481 ggctttgaat ctaacgaaac aatagctgca attcatagac atgatgagcg gctagggaaa
     3541 attattcaaa ctttaaaaga cagtgatcta tacgaagaaa gtacaattat tgcccttggt
     3601 gatcatagcg ctttaagtga aaacaaatcc atccaattaa atgtgctatt ccatcaaaga
     3661 ggacttatat ctcttaataa aaaaggcaaa ttagtagact ggaaagccta ttgccaaagt
     3721 tgtgatggct ctgcctatgt atatgtgaaa gacaaaaatg atacggatac aattcgagaa
     3781 gtacaactac tccttgaaga actgctgcaa aataaacaga atggaattga atttatactt
     3841 catgatgaag ctgcgaaaga ccgcggtgca gatggtaatt gtttatttat gttagaagca
     3901 caagagggtt attatttcaa tgaaaactat acaggagatt ttataaaaga aattactgaa
     3961 aaagatgtta cgcctagtaa aaaatataca tttggtacgc atggatactc tccaacaaaa
     4021 cctaactatg aaacaatttt tatcgctgct gggaaaggaa taaaaagcgg cgttaccgtc
     4081 ccgtacatga ggcttattga tgaaggtcca actatcgcta gactactcgg tttacactta
     4141 ggtgaaacag acggagcaat tgtagaggat ttactccaat tgtaaagaac tgtgtatata
     4201 tgtaaaagtt atgtaaaatt catcactgtt tctcttttta taatttttat ttttgtacac
     4261 tgttagtaaa acaaatttaa gggggaacat taactgttag taaaacaaat ttaaggggga
     4321 acattatatg aaaaaaatgt ccagacaaga aaaaagctgg atattatacg attgggcgaa
     4381 ctcggtatat tcgctcgtca ttacaactgc attatttcca atttacttta aagcagctgc
     4441 aaaagaagct ggactatccg gggcaacttc aacagcatat tggggatatg caaactcgtt
     4501 cgctacactt ttaatttcta tacttgctcc tattctcggc acagttgctg attataaagg
     4561 atttaaaaaa cgatttttca cattcttctt tggactcggt atcgtattta caagtatgtt
     4621 agcagtcgtt ccaacatctc agtggtactt attattagga tgctatatgc tcgccttagt
     4681 cggttttgct ggagcaaaca ttttttatga tgcattttta gtagatgtca cttctgaaga
     4741 tagaatggat cgaatttcta cgcgaggttt cgcattaggc tatgttggga gtactattcc
     4801 tttcatcggt tgtatcgctc ttattattct ttctcaaaaa ggaactatcc ctttatctgt
     4861 tggtattgct agtcaaattt catttgcgat aacagctctt tggtgggggt tatttacgat
     4921 tccaatgcta aaaaacgtag agcaaaagca ctatattgaa cgtcacccta gaccaattac
     4981 aatgagcttc aaacgccttg ctgctacttt taaaaatatt aaagaatata aaactgtatt
     5041 catgttccta atcgcttact ttttctatat tgatggggtc gatacaatta ttaccatgtc
     5101 cacggcttac ggaacagatc tcggtatcag tgcaacgaat ctattaatca tattatttgt
     5161 aacacaaatt gtcgcttgtc catttgcttt attatatgga aaattatcag caacatttac
     5221 aggtaaaaaa atgctatatg tcggtatcat tatttatatc atcatttgca tatatgctta
     5281 tttcttaaaa acgacacttg atttttggat tttagcaatg ttagttgcta catctcaagg
     5341 tggtattcaa gcactaagtc gttcatactt tgcaaaacta gtaccaaaag aatctgctaa
     5401 tgaattcttc ggattttata atatctttgg taagttcgcc gcaattatgg gcccggtatt
     5461 agtcggtgtt acaacgcaat taacaggaaa aacaaacgct ggtgttctta gtattattgt
     5521 tctgtttatt atcggtggat tcttattaac tagagttcca gaaaataata catccgttac
     5581 accacctagt ccaaagacta aaacactata agaaaagatc ctcttctcat gagaagagga
     5641 tcttttttat ttttaacggt gcgccttata ataaacgact ctactgcttg tacaaaaata
     5701 atttatcaac agttgttcct aatacttcag ctaaacggaa tgctaacgct aagcttggat
     5761 catatttatt attctcaatt gcatttatcg tctgtctaga aaccttgcat ttatcagcta
     5821 atgcgccttg tgaaatatta ttttcagtgc gtaattcata gatttgattt ttcacaccat
     5881 tgctcctaac ctgtaaaatc atttttacaa catcagtata taattggctc atatagttgt
     5941 caaaagttcc tcaaagaaaa agggagcaat tttgctccct taaaatagtt atttcgaagc
     6001 taacgaattt gttagtttct ctttattaac gacatcttct ttctttattt gcatgcgtag
     6061 aactggccct atcgctaata aaacaagtgc cattgctata caaaacacaa taactagtga
     6121 agttagttcc tttaatcctc cagctagtga agttccaatt agcattgccc ccataaacag
     6181 tggtaaaatc gtcccgttta ctcttccaac catattttct ggtacaagtt gaatcataag
     6241 cgtaccgaca acgatattaa cacaagctaa acaaatacct gttccaaatc tcatgaaact
     6301 agtaatccaa aatgatgtag atagcccttc tactaaaaat gacatcgcta atatgctcat
     6361 accgaatacg aacatctttt tcggattcac ttttgaagcg aaaactgcag caacaatacc
     6421 accgattaac atacctattc cgtcagctgc tgctaaatat tgaaccgctt ccttttccat
     6481 tccaaggcgt tctattacaa gaaacacctc taatggattt gttaatccaa cagctaaacc
     6541 cataatagta aaagtgatcg taatcatacg taaatttttc gtatgaagaa catacttcca
     6601 accttctttt atatcatttt ttaatgaatc tctcgccact tgctcttttt caacccattt
     6661 tggtaaaaat gaaaggatga tagccgataa caaaaataga atgattaaac tatatagtga
     6721 cgtaaataag ccaagttgtg tatacacaat tgatcctaca actggtccaa aaatcataaa
     6781 taatgactgt aatgtttggt taaatgcaat cgcatttgct acctcttctt cttttacata
     6841 gcgcttaaat atacgcgaag atgagggctg agaaaactga cctacaatcg cggaaatgag
     6901 tgttgcaaaa aatatagcct gccaataatc aaattttaac aatacgacaa ttcctataat
     6961 agacagtaca cttaacacat ctccagcaac cattgttctt ttcggattcc aacgatctgc
     7021 taatgcacca ccaatgaacg agaaaataaa gataggtgca tactccatga cagataatag
     7081 agacactgaa actggatcat tatttgtccg ctccattatg aaatataaaa gagccatatt
     7141 tctaatccaa attgcaaatt gttgtaaaat atcagatgcc ataacgagca taaatgctcg
     7201 gtttttaaat aaagcgttca ttttcattcc cctttcacaa accgaccgtt cggtctaatt
     7261 tattctttaa gaaaagcaac tgacttatta ttcagctgcc attcctttta acaatacatc
     7321 tattgccttt ttataaatac gcttcaactc tttataatct agctcgtagt aaagtactcc
     7381 aagccctgat aataatccat tcacaatata cataagatca cgagtattat cttcacggaa
     7441 ctctccagac tgtatacctg cttcaattaa tttctcaaac ataacatatg attctctagt
     7501 taaagctaac agttcatcca gaatctcttt acttacaact tggctcatag agaattcctc
     7561 tattgcattt gaaattggtt gctgtatgtc ctctacatga tattccgcga gaccatatag
     7621 tttttcagta ctagtgctat acaacttctc tttttcattc catttttcaa gccaatcata
     7681 cgtatgctgt ttcactacaa ataaaaataa atcttcttta cttttaaagt gatagtaaat
     7741 acttccttta cttcgctctg taatttcaca aatctcttcc atagatgtag ctgcgtagcc
     7801 cttctgtgaa aatagacttt ctgctttata tgcaatttct ttctttatct cttctgcgct
     7861 tcttctcata ttcacacctc tttaaaccga ccgttcagtc taataataac aaatcaaaaa
     7921 cctctatcgc aagaggctat attccttatt taagaaaatg tactttcaaa ccaagttcga
     7981 atcatatgta ttgttccaaa tttaaatgtt aatttaacaa gaaatacgcc tcccgcagct
     8041 aataaaaata acactacttt ccccttattt ttcactctcg gttccctttt catttccatt
     8101 ccccttagta tgttaaaaat attaatcaaa cgtttgttta actgtgttta tgcatatgta
     8161 agccaactaa tcaaacgttt gtttaaaaag aaatacgcct atataaggcg cattttcatc
     8221 aatcaccacc accgcagctt cccccgctat ctcccccaaa agaccctcca caatcatgtg
     8281 aaccgccatc atgcgagcta tcattatcag atccagcaaa gaaaaataat ggtgatgagc
     8341 tgttagatga attatgaatg ttattttgtt ttgtaagatt taccttcttt ttgttcgatc
     8401 gaactgctgt tacgattatt ccaactacaa caaataatag tatgacaata ataaattcca
     8461 tataaaagcc tcccttattc ctcgaataat tgaatggttc tctctagatt tttaagtgaa
     8521 atgaagcgcg attcccgaag gatctctttt ccattataaa ataataaaac tgttggtcct
     8581 gtaaatactg catatcgccc cgcaatctct tgcatatctt gtagtaatat ctctattttc
     8641 tctacgtaat cataattctc taatacgtaa tttactttcc ttaacataac atcgcaaaca
     8701 ccacaatttt ctgttttaat gaacagaagt accaattgtt gttcttcaat atatgtcgct
     8761 aattcttcta tcgttttaaa tttatgcatc ttatccctct taacgcaatt tatgaaatac
     8821 tctatcttga tacatacgaa aagctgaact atctttaatc cttctctttt ccattacctg
     8881 ctgaaaacga agcgtttttg ctgttaactc ttctcgtaat ttctttctct cttcttcatc
     8941 ataacagcaa gcaattagat cctctatttt taatatatct ttttgtagtt ccatttctga
     9001 tggaatcatt cccgcatttt ttaaaatttt ataactcatt ctaagttctg gaggtaccat
     9061 tgaaagatct tctaattgta gtggttttcc ttttcccgga agataatcaa gatcaccatt
     9121 ccgtattgct tgtcgaattt tttcttcagc aatgttcaaa aacacatcca caccattccc
     9181 tcctttacat atttttacta ttattttaca tgatatttcc ttatctttct acgtctttaa
     9241 taattgactc cagacaattt tttctcaaat ttatttataa taagcttttt cctcccatac
     9301 cgatctttcg ttttcatata tagtttgtat tcaagccttt ttgtattgag aaagtatatt
     9361 ttaacttaat aaagcgttta cactaaatct tacatttgtt acgatttaat cacccccagc
     9421 tcccttgtat agacttcgtg atgtctgatc attttatcta gacgtttcat acgtctagat
     9481 tcattttgat ttattggcgt atgcctttaa atatattttt tattttgaaa ggagaaatgg
     9541 ctatgaggtc tcaaaaattc acactgctat tactatctct actacttttc ttacctcttt
     9601 ttctcacaaa ttttattact ccaaatctcg cattagcaga ttcaccaaag caaagtcaaa
     9661 aaattgttgg gtactttcct tcgtggggcg tttacggacg taattatcaa gttgctgaca
     9721 ttgatgcatc aaaacttact caccttaact atgctttcgc ggatatttgt tggaatggaa
     9781 aacatggaaa cccttctact catcctgata atccaaataa acaaacgtgg aactgtaaag
     9841 aatctggtgt accattgcaa aataaagagg ttcctaatgg tactctcgta ctcggtgaac
     9901 catgggctga tgttaccaaa tcgtatcctg gttcagggac aacttgggaa gattgcgata
     9961 aatatgcccg ttgcggaaat ttcggagaac taaaacgatt aaaagctaaa tatcctcact
    10021 taaaaacaat tatttccgtt ggtggctgga cttggtctaa ccgcttttct gatatggccg
    10081 ctgatgaaaa aacaagaaaa gtatttgctg aatctacagt atcttttctt cgtgcatatg
    10141 ggtttgatgg cgtggattta gactgggaat atccgggcgt tgaaacgatt cctggtggta
    10201 gttatcgtcc tgaagataaa caaaatttca ctctccttct tcaagacgtc cgaaatgctt
    10261 tgaataaagc aggtgctgaa gatggcaaac aatatttact aacaatcgct tcaggcgcaa
    10321 gccaacgcta cgctgatcat acagagctaa agaaaatttc tcaaatactc gattggatta
    10381 atattatgac atatgatttc cacggcggat gggaagctac ttctaatcat aatgcagctc
    10441 tatataagga tccaaatgac ccagcagcaa atacgaattt ttacgtagat ggtgctatag
    10501 atgtttatac aaatgaaggt gttccagtgg ataaactagt attaggcgta cctttttacg
    10561 gacgtggctg gaaaagttgt ggtaaagaaa ataacggaca atatcaacct tgcaaaccag
    10621 gtagtgatgg gaaacttgct tctaaaggta cttgggatga ttattctacc ggtgacacag
    10681 gtgtatatga ttacggtgat ttagcagcca attacgttaa taaaaatggt tttgtacgct
    10741 actggaatga cacagctaaa gtaccttatt tatataatgc aactacaggc acatttatta
    10801 gctacgatga caatgaatct atgaaatata aaacagacta tataaagacg aaaggtttaa
    10861 gtggagcaat gttttgggaa ctaagcggag attgccgtac aagtccaaaa tatagttgta
    10921 gtggtccaaa attacttgat acgctagtaa aagaattact tggtggacct attaaccaaa
    10981 aagatactga gccaccaacg aatgttaaaa acattatagt tacgaataaa acttcaagct
    11041 cagttcaatt aagctggact gcatccactg ataacgtagg cgttactgaa tacgaaatta
    11101 ctgccggaga agaaaaatgg agtgcaacaa caaatagcat tacaattaaa aacttaaaac
    11161 ctaatacgga atacacattt tcagtaattg ccaaagatgc ttctggaaat aaatcacaac
    11221 ctaccgctct tactgtcaaa acggatgaag ctaatacaac acctcctgat ggaaatggca
    11281 ctgctacatt ttcagtcact tcgaattggg gaagcggtta taacttctcg attataatta
    11341 aaaataacgg aacgattcct attaaaaatt ggaaattaga atttgattat agcggcaatt
    11401 taacacaagt ttgggattct aaaattagta gtaaaacaaa taatcattat gtaattacga
    11461 acgcaggatg gaatggcgaa attcctcctg gtggatcaat tacaattggt ggtgcaggaa
    11521 cgggtaatcc tgccgaactt ttaaatgccg tcattagcga aaactagacg taatatccat
    11581 taattatttc actaaagttt gaatttaggt ttgagcaata cctcctaaat tcaaactttt
    11641 aattttatga aaaataaaaa gcatcacaat aacctattat aattaatttc taatatgaag
    11701 ttgatatgaa gttaatttga attttacatg aatttccttt aatttctatt gtcttcctat
    11761 aatatccaca ttattcttta aatataggaa ttattttcat tccactttga actatctata
    11821 tatataaaga aagatagtca cctgttaggg aaaggctttc gtattattat aaatataaca
    11881 aaagaaaaag cacgcttata agcgcaccat aagagtgctt cttcatacaa ttctcatgta
    11941 agagttctcg aaaatcatgt taatcacaaa gaaaagacat tagctcataa aagctaatgt
    12001 cttttcttta ttcatattgt tcagcattcc actcttctat attccatact tttgttatcc
    12061 acgattcata gaaagaaggt tcatgtgaga caattaaaac cgttccttta tattgttgta
    12121 acgcttcttt taaagccatc ttagtttcta catccaaatg attagtcggt tcgtctaaaa
    12181 ttaaaacatt gcttttcgtt gcgatgagtt cacataaacg cactttcgtt tgctctccac
    12241 cgcttaataa atgaataggt tttaatacat gttcttcttt caatccacac ttcgctaatg
    12301 cttggcgcac ttctttcttt gtcatatctg gtcgctctgc ccaaactttc tctaatggtg
    12361 ttatttctga agcaaactct tcctgtgcaa aataagcagg atttactcgt tccccaacaa
    12421 aatttgaacc acttagcggc tttatttgat ctaataacgt ttttaacatt gtcgtttttc
    12481 caataccatt atgaccaaca atagctatct tttctccttt cttcacttgt aaattcaatt
    12541 ctggaaataa cgaatcacta taacccactc ttagtttctc agcctgtaat atactactta
    12601 ctggctcatt ataaacagta aaaacaaaac gggaccgagg tacattttta accttttcaa
    12661 ccctttgcat tttctccaat actttctctc gactttttgc ctgttttgct tttcgaattt
    12721 tatttttttg aataaatgtt tctaactgag caatttcttt ttgttgtttc gcatacgccg
    12781 attgtaattg tttcctttgc aattgataac tttgtaaaaa cttttcataa tcccctacat
    12841 atcgcttaac ttttcgttct tctagatggt aaatgacatt cgtaatatta ttcaaaaata
    12901 cttcgtcatg cgaaatgata atataagctt tttcatacaa cttcaagtac gattgcaacc
    12961 attctatatg tgctgtatct aaatagttcg ttggttcatc tagcaataaa acatcagctt
    13021 tttctagaag aagctttcct agtaataact ttgtccgctg tcctccactt aactttaaaa
    13081 catccttttc caatcctatt tcaaacagcc ctaaaccaat tgccacttct tcaatttctg
    13141 tatgaatttg atagaaatta gagttttcca atatagtttg taactctcca taccttacta
    13201 acaatttttc tacttctact acttcagcca tctcttctgc aatttttaac atttcgtatt
    13261 caatcgcata caagttagaa aatgcacttt gcaagtatcc ttcaattgtt atcccttctt
    13321 gtaaatctat atgctgctgc aaaaatccaa cctttacatg tggaaaccat tcaatgttcc
    13381 catcatcatg tataagttct cctgttaaaa ttcttagcag tgttgatttt ccaatcccat
    13441 ttttccctac taacccaaca tgctccccct ttaataatcg aaagcatgca ttatataaga
    13501 tggttttctc accatacgaa tgacttaaat tttctactgt taatatactc atttttttct
    13561 ctcctttact tatcgtccat aagctaaata gagagaccaa cagtatgaag ccttatttaa
    13621 ttatgcatat aaaaatgggt aaggtgaata caccttaccc attacatatt atcgtaaaaa
    13681 aggattaagg ttctttacct gctgtcttca atttagctta atcttaaaaa atgggcagac
    13741 ttctcccata tcaagctaaa accatttgaa gaacagttga taaagtcatt ttatcctttc
    13801 actcctttaa catttgttat attaagagta taaactactc tgttatattc tattctctat
    13861 tttccctttt gttccttctc catcttttca tattctaaaa aaagcctctt aacagtaatt
    13921 atactaaaaa ctgttaaaag gctttttcta ttttttcata taaggagcta acacacttaa
    13981 aatctcttct ttatcctttt ttaattcgag tgacgttaac atatccatcg ttctcagtct
    14041 aggtaatttc acttgtacct cgccaactat tgacgctggt ctttgagata aaataaatac
    14101 gcgatctgaa agcaagattg cctcatctaa gtcatgtgta accataacga ttgtttgctt
    14161 ctcttgatgc caagagttta aaagccagct atgtacttcc atttttgtaa atgcatctaa
    14221 ctttccaaaa ggctcatcaa gcagcataat tggcttttca cacaaatatg tgcgcagaaa
    14281 actaattctt tgacgcatac caccagacaa ttcatctgga taatggtctg catattcatc
    14341 tagttcgaac tgctttaatg cttccattcc ttctgtcagc ctttgttttt tcggctttcc
    14401 ttcaatttct aacggaagaa cgatattttg caaagctgat cgccacggta gtaataaatc
    14461 ttgttgtggc atataactaa caacatcttg ctcttgtact tgcttatctt tatacgttac
    14521 gttcccgctt gttggttttt caacatttgc aatcatgttt aataatgtgc ttttcccgca
    14581 accactcggt cctacaaagg aaacaaactc tccctcttgt atagaggcac taatattctc
    14641 taatacattc tttccgtcga aagatttcac tatatttttt atttgtaatc cgctcatttt
    14701 tcacttggaa ggaattcatt tgtaaaagca tcttttacat cgattttctt tttaataact
    14761 ttgttgtcat ataagaaatt catgtaattc gtccaaattt cttccttctg tactccccat
    14821 gctttcgcat catcttgata cttcgtactt aaccatttct ggctttcttg aactaaatct
    14881 ttatttacat ctggaacagc tttaattaga atatcagcag cttctttcgg ttccttaatt
    14941 gcaaaattat aaccttctgt tgttgcactc ataaactttt tcacaaagtc tttatcttgc
    15001 ttcgtatgtt tttcactcgt aataataaca ggactataga aatcaagcgc tgggtctaag
    15061 tctttcacca taatcgtatt taactctttt ccttggcgct tcgcttcaat tccatcccat
    15121 ccgtaataaa tccattcaaa gtctgcatca cggccgattg atttaaagaa atcggtttgt
    15181 cctaagatga ttttttcaac tttattaaaa tcagcttgat gcttatccat aatcgtcttt
    15241 aatgtcgctt cttctgctgg tcctccccag ccgccgtaac gtttaccttc aaaatctttc
    15301 ggtgacgtca tattatcttt cttaagtgat gcaaatgctg aagtgttatg ctgaataatc
    15361 gctccgacag atacaacagg aatcccttcc acacgagcca acgttacatt ttcttgtgcg
    15421 cttattgcga agtcagcttt tcctgatgct atcatttgct ctgctgttac attgtcaccc
    15481 ggttgaataa tttctacatc taatccttgc tttttgtaat aacctttcgt ttgtgctaca
    15541 tataagccag tatgattcgt atttggaaac caatctaata ctacttttac tttttgatct
    15601 ttacttttac tttcttcttt cttcgccgga ttacatccag ccacacctac cgctactaag
    15661 gcagctaaca taactttcaa accttttttc attttctgcc gtcctttcta tatatccatg
    15721 gtgctgttat tcttgccata aactctacga taaaatacag gcacaatgtc accataacga
    15781 tgattgctgc aacaccaaat actcgggcag tcaaaaatga ttttgtagcc ctcgtaagca
    15841 taacgcctaa tccttcactt gcaccgagcc attctccgat aattgccccc attacgctat
    15901 atgtaactgc aatttttaag cctgagaaaa agtatggaag cactgctgga aattttactt
    15961 tctggtaaac ttgccatttc gtcgccttca ttgtttgtaa cagcttcaac atgtttttat
    16021 ctactgtttg aaaaccttct aaaatactaa gcgcaattgg gaagaaacaa acgagtatta
    16081 cgaccattac tttcggcaac atcccatatc caaaccaaat aataaatagt ggtgcaagta
    16141 caacaattgg aattgtttgc gaaataacga gcaatggatt tattaaaata cgaaataacg
    16201 gtataacgtc cataataatt gcgatgctcg tccccaataa aattgcaaag aatagtccaa
    16261 ttataacttc ctgcagtgtt tgcatcgtat ttggtaatag taaatctttc atcccaatta
    16321 attcttgaac aatggcagaa ggctttggta aaatccacgg ttcgatttta aataatgaaa
    16381 cagatccttc ccatatcgca atgagaagga taagccaaat agttgtaata agtttagatt
    16441 gcttctggtt ttgcatattc atcacggtac ttccaaacct tttcatctat cgttacacca
    16501 gtgcttggac gataatggat tttaatagaa gtaatcactt cttctgctcc agcatcgacg
    16561 caagcttgtt gtgcacgttt aacgacatca agaagtacat ctaattctcc ttccaaagtt
    16621 gtttccattg cccctacttc ataacgaact cccgattgtt gcacaacttc aattgcttta
    16681 tcgacaacag aatatacatc tttcgttttc gcttgtggta ctactgaaaa tgacattgta
    16741 acttgttgtg acataataaa atccccctta taaaattaaa tttcaaaaat aagaaaaggc
    16801 tttcctactg cgtaggaaag ccttgtatgc aagttattat agaataacat atgctacatc
    16861 actttaagta actccctacg ctggcattat ccagatcagg ttgagggtcg atgtttactt
    16921 acatcctctc agccaattgg ctccccggtc cttaattcgt tttcattgta gcatgattta
    16981 ttttattgaa caaacaaaag catgcataat catttcatta tttttggaaa ataaccaact
    17041 ttttcaccat gagctaataa ctgctgtata aattctttat taattgctgg tactttcaat
    17101 tcttttttct taatccattc attcgttcta cgcgtaccca ttacaatttc agattgctgc
    17161 gctccatctc ctgcaacttg agaagcaatt aactctgcta ttacttcatt tccctttgct
    17221 aattcaagtc cggcattttc atattctgaa agtgtaacca gttcaagatt gtatccacac
    17281 tctccaatta gctgtataaa ttgttcaaac tcaatttgat gtggatgaca gatgtgcaat
    17341 gtttctccat ctatttgtga atcttgtaca tacgttacaa ttgatttact agcaaaatca
    17401 attggtgtga aatcaacttt ccacttcaca tttggtgctt ttccaattaa tagcattgtt
    17461 ttaataagac gataaaatgc gtttccttca atattttgtt ggaacgaacc tgtttctgaa
    17521 tgacatgcta aattacctgc acgataaata tttccacgca aaccattttt cattgcttca
    17581 cgaacaatgt tttccgcttg tagtttacta tttgaatata cattctctaa gtctacactg
    17641 taattaaaat caccagtttt catgtatgta tcccattgat ctactgctaa ttctaacggg
    17701 ataccaatcg tagaaataaa atggaatgta gcatcttttt ccactaatgc tagcatacgg
    17761 ctagttcctt ggacatttat attttcaaat tgttttacat ctccaaaatg tcttacatct
    17821 gcaccgcaat gaattatcgt atccatctta gaactgatga acataaattc ttcttcgctc
    17881 atcccaagat actcttctcc cagatcacca gctacggcct gtatacgctg taaccattct
    17941 tcacatatat cattaaagta agctgttaat gtatctataa ttctttgctg cacatctttg
    18001 gttggtctta ctaaacaata aatagtagca gatgtatctc tcagcaattc atataatatg
    18061 tgtgatccta aataaccagt agctcctgtt aaaaagacat ttgaaatctg ggtttcttcc
    18121 aaaacgtttg catacgtaat agtatccggt tcgtgaatca ctttatattc acgaaatact
    18181 tcttctttct ctacttttac ttctcgctca attcgagcta atccatatat cgttctttct
    18241 ttaaagaaat cttgaattgt taaatgtgag aaatcttctt ttaacaatgt taagactcgt
    18301 aatactttca atgaatgtcc accaattgta aagaaatcat catgcactcc aacttttgaa
    18361 attcctaata cttccgccca agcgttcgct atttgttttt ctgctttatt agaaggtgca
    18421 acatattctt gtagacgaac cggttcatac ttttcttcta actgagctaa cttcttaaca
    18481 tcaatctttt tattaggtgt aagtggtaat tcattaatat aaattagttt agatggcacc
    18541 atataatctg gtaattgctc ttgtaactga taaactaatt ctggtatttc ttttttattt
    18601 aaagttgtat agaacgcgat taaatattgg ctaccttcct tactcttctt agcaaaaaca
    18661 gcattttctt ttatattatg attttgagaa attttacttt ggatttctcc tagttcaata
    18721 cgatgtcctc taatttttac ttgatcatct ttccgatgta aaaactctat atttccatcc
    18781 tctagcaact taacgatatc acctgtttta tatatattaa ctataggatt aaaagggttc
    18841 ggaataaaag cttcaattgt tttattaggt ttattaaaat acccttttgc taatcctact
    18901 gaatctatat ataattcacc aggtacacca attggacaaa gattcatatt ctcatccaaa
    18961 atcataactt gataattaga acatggttta ccaatgggaa tactcgcaac atcctcattt
    19021 aactgactag gtattttata agttgtcgtc actactgtac attctgtcgg tccgtataca
    19081 ttatgaattt caacatttgt acgtattctt tctctccaca atttaataac ctctacaggc
    19141 aacatttcac cgccaatcgc aattcttttt agggaagcta gcttatatat atcttcttct
    19201 gctaaataag ttgctatttg tcgaacaaaa attgttgcta atgccaagat cgaagttgct
    19261 ttcactttat agattgcatg tgcaaatgct tctacagaca atcgctcttc ctctaataat
    19321 acatacaagt ttcctccgca gaataaagaa gcaaatgact cccatacaga agcatcgaaa
    19381 ctaaaggaag gaaattgggc aaatacatcc tcttctgtca attcatattg cttttgcatc
    19441 caagtgtaca gattaacaac gcctctatgt gctaacatcg ttccctttgg attccctgtt
    19501 gaaccagatg tataaatcat ataagctaca tcatcacaat gaatagacaa ctttacatct
    19561 atatcttcac aagtttcact atcatacatt gaaactgttt gaaccccatc acatgttata
    19621 ggcgtctctt tcatcaatat aactttcgct tggctatctt gaataatgta ctgtattcta
    19681 ctttccggat aatctggatc aatcggaaca tacgctgcac cagcttttaa tatagctacc
    19741 atacttacta ctgtgtctat gctacgtttc ataaatattc caacatagtc tcctaattgg
    19801 acgccgtttt taattaacat atgagctatt tgattacttt ttttatttag ctcctcataa
    19861 gttaaagtac cttcccttga agataaagct atacgatttg gaaattgagt aacagtatta
    19921 tagaacatat cgacgatgct tttctcagga tatactgctg tcgtatcatt cacttgacta
    19981 taaagtgcca tctcggcctc tgtaataaca ttaaaatcat ttatataatt attattattt
    20041 tgtaatgtat tgattaaaac accttgtatt tgttgtgcat aacgagtaat cgttgtctct
    20101 ttccaattaa cactattaaa tattatttct acgctttgca tatttttact aaatacaaat
    20161 tgtaatgtat tcgtgtcttg tagctcataa tatgtttcac caataataat aggtgacatt
    20221 tcatataatg tattaccgtt ttgaaactct tctatttctt cctcattcat ttctttaatt
    20281 tgttccagtt gctcttcaat ctgtaaattc aaactttcat aggagagaaa attagaaatt
    20341 tcaatagtaa tcggaaataa acttcctctt acatgataaa gcacgacaat atgtttttct
    20401 ttagaaatat gatataacca cgttgcagtc gctcctatta aatctacaat gtgagtcaaa
    20461 tttggaaata gttcagtttt tctttttacc ccaaattctg ttccttgaac atctttaggt
    20521 attttaatac ttccttctac ttttcctaaa aattctttta ccatctcatt ataagaaatt
    20581 gctaatttca tatttatgta aattcctctc tcaaatataa taaaggtgtg aaaattcaca
    20641 cctttttcat cccttattaa cgggcaaatt agttcaattc ataatcaaag gggggatccc
    20701 ccttcgatta gaattgatct ttcttcttat tcacttttaa actcaccaat tagctcttgt
    20761 aattcctgag aaagccaact taaagaagtc gctaattctg caatatcttg tactgatatt
    20821 tcttgctctt tcatgctttc ttcaacatta ctactgctgt tggcataagt atttgcaata
    20881 tgtgataatt catttacgac ttgaacaata ttctggctat tttgtaaaat gtcactcgaa
    20941 ttaccagaga cagcttttac ttgatctgta acagattgcg ctgattttga aattttttca
    21001 aagaaatctc cactactttg aacaagtgaa attccagttt ctacttcttt tgaacctttt
    21061 tgcattgaaa ctacagcatc ttctgtctca gcttgtgttt caccaattaa tttcgctata
    21121 tcttttgcag acgcttcagt ttgttctgct aattttcgta cttcatcagc aacaactgca
    21181 aaccctcttc cagctgctcc agcacgtgaa gcctcaatag aagcatttaa agctaataaa
    21241 tttgtttgat ttgaaatacc tgtaattaca gttacgatat cactaatttc ttttgacctt
    21301 gtttctaacg aataaatgat ggaagataaa tcctgtactg cattttggat taaactcatt
    21361 tgattaataa tttgtccaat cacttcatta ccttcaattg aatgttgctc cataccttca
    21421 gaagcaaccg caacttgttt tgcagcccca gttatctctt ctaccttatc ttccattcca
    21481 tgtacaattc ctaaacattg ttgtactgaa gttttttgag actgtgcccc tactcttaaa
    21541 ccttcaatag aacttgcaat ctcttgaact gccatactgt tttcctctgt actcgccgac
    21601 aattcttgtg aagaagaaga aacttgctca gcagtttgcc ttactttatc tataatccct
    21661 ttaaattttt caatcgtgtt attgaaataa acattaataa ttccaatatc atctggtctt
    21721 tcttttaatt taatacttaa atcaccttca ccaattttac gtaatccttc tcgtaaatct
    21781 tttaatggag ctagcgagtg acgcacgata aagaattgag taatagtcgc aattgctaat
    21841 gaaataatga taaagagtaa gccctgtatc ataaacttct cttttgtaat aggaacaatg
    21901 gaagcatcta agtcagccgc aataattgca acaatattgt tttctccatc tgtaattggt
    21961 tctaatattg tcacccacga acctatttca tcttcatata cttctgtcat ttgggccttt
    22021 ttcgtatcaa tgaccttatc gtatgccttc atccaatgag cgggttgttc ataataatct
    22081 cccggcttta tagggaatgc atttgttaac tctgtagtca aaccaacgag ttgtaattcc
    22141 cgcttttcat tcggttttgc tcctgtaaca tacgtttgtc caacactttt caattctttt
    22201 gacacttcat ctaatttctc tgttaacttt tcttttttca ctttttcggc tgtaggatct
    22261 ttcgccatgt ctctaactaa ttctacatcc aattttttca acactatttc tcctgtttca
    22321 atagactgtc tttcaaataa agacatcata ctattttgaa acatgttgaa acttaacgcg
    22381 cccatacttc caacaagtgt caaaataact aatacggtta ataagacgtt cttttgaagg
    22441 aacgataact tatgccaata ttttttcatt aatatccacc ttccttaatg atactaaata
    22501 aaaaaacaaa atatatgaat attttgttta aagatgtttc tcaatatgtt cgagaataaa
    22561 aaaaagccaa tgtaaaagca ttggccaaga ccaaccctat ccgtccggta actggctagc
    22621 atagcctttc gaccttagct cctgtagttt tgcgtcctca tgtttccatc agtttgcctt
    22681 tctcgctgaa cgagttgaac gatatgggag ttctatgaga atcatatatt ctctatcaaa
    22741 gattacaaca tataaatcaa aatgtctact tatttagaga tataaataca aatttttaaa
    22801 gaattgcttt ttcgaaataa tttcaaaaag tacgtgaatg ttactttttt tgtgttatat
    22861 aataaaaaat gtataaataa caaggatttc ttcgggtatt tatttaattt tcattcaaat
    22921 taaactattc gaatatatct taactaatga atttcggagg tagtttatca tgttttggct
    22981 acaatttctt accttgttac tctgtatttt tattggtgca cgcctaggcg gagttggttt
    23041 aggagtaatg ggtggagttg gtatggcaat actcgttttt gtcttccact tacaaccgac
    23101 cgcgcctcct atcgatgtaa tgcttatgat tttggcagta attacagccg ctggtgcttt
    23161 gcaagctgct ggaggaatgg actatcttgt tcacctagct gaaaaagcat tacgaaaaaa
    23221 tccaaagcgt attacttttt ttgctccaat tgttacttat ttattcacac tatgtgcagg
    23281 tactggtcac gttgcctatt ctgtacttcc tgttattgca gaagtctctc gtgaatcagg
    23341 gattagaccg gaacgcccaa tgtcgattgc cgtaatcgct tctcaacaag caattacagc
    23401 tagcccaatt tcagctgcca cagttgctct tttagcaatg ttagctgact ataaaatcac
    23461 tttattagat attttaaaag tgagtattcc ttctactttc attgcttgta tgttagcagc
    23521 attcgttgct agtaagatgg gaaaagaatt aaatgaagac cctgaatact taaaacgatt
    23581 aaaagaagga atgattccta agcttgaaga gaaaaaagaa tttgtaggtg taaagggcgc
    23641 aaaattatca gttatccttt tccttgtagg aaccttcctt gttgtacttc ttggttcatt
    23701 tgaagcactt cgtccaggat ggatagttga tgggaagtta gcccgtcttt ccatgccgaa
    23761 cacaattgag atggttatgt taactatcgc ggctcttatt attattttct gtaaaccaaa
    23821 tgtagaaagc attgtgtctg gtaacgtctt taaagcagga gcaacagcag ttgttgctat
    23881 tttcggtatc gcttggatgg gagatacttt ctttaatgga aacttaaata tgattcaagg
    23941 atccattcag catttagtaa caagtgcacc ttggctattt gccatcgcac tattcattct
    24001 atctatttta ctgtacagcc aagcagcaac agtacgtgcc ttaatgccac ttggactatc
    24061 ccttggtatt ccaccagcac tactgattgc gatgttccct gcagtaaacg gatatttctt
    24121 cattccaaac tacgggacaa tcgttgctgc cattaacttt gaccgtaccg gtacaacagg
    24181 tattggtaaa tacgtattaa atcatagctt tatgattcca ggcttaattg caacatttac
    24241 ttctatcgga attggaatgc tcttaatttc aattatgttt taaagaaaaa gcacaaacct
    24301 ttatttaaaa aggtttgtgc ttttttaatc aaacgtttgt ttaaattttt tgggcagtct
    24361 acttctcgat gtagcactta aaatactaca tgtccttttc tacaaacttc tctttacttc
    24421 ttcagctaat tttctcgtac tttcatatgc agattcagct aaactaattg ctgaaacaac
    24481 tgaaatacca tccgcacccg cttctataac tgccgctgta ttttcaattg taatcccacc
    24541 aataccaacg attggcactg taattccttg ttctctaaaa taagctaatc ctttcgttcc
    24601 ttgaaccgct ttcgtatctt ttttcgtact cgttgggaaa ataggtccaa cgcctaaata
    24661 atctgctccg ttttcgattg caaagcgtgc ttcttcaatt gtatgagcag atacgccgat
    24721 aattttatct cccatttttt cacgaacaga tgtaattcct tcatcatctt gtcctacatg
    24781 aacaccatct gcatctaatt caatggctaa ttctacatca tcatttacaa tgaaaggaac
    24841 actatattcc ttacaaagcg tctgcaattc ttttgcaaag cgcactctat ctcctccgat
    24901 taaagaacct tcccccttct cgcgaaactg aaaaagtgtc actccaccat ctaacgcttc
    24961 tttcaataca gctaaaggat ccctcgtgca gttattactt cccataataa aatacacttg
    25021 caataggtta gacattttct ttgtttcaat gcgcatcatg tgtttcatcc cccttactct
    25081 aactcctcaa tcttcccata tttctctata tcagctgaag ttgtattcgc taattgattt
    25141 aaaaattcaa tttggaaact acctggccct ttttctactg ttttagcagc tgccagttcc
    25201 gaagctacac cataaaacgt taatgctgct acagttgcct ttacataatc tttttcaact
    25261 gctacaaatg ctcctattac tgaagttagt aaacaacctg ttcccgtaac tttcgttaaa
    25321 atagggtgac cgtttcgaat aacaatagtt ctctctccat ctgtaacaac atcttctttt
    25381 ccagtaataa ccgcaactgt atttaattcg tctgctgcct gccttgcaat acctacaaca
    25441 ttgccatttc cagtaccagc gtctacccct ttaatttccc atttctcatt aataacgttt
    25501 gctatttcag ccgcattgcc gcggataatt gctaaatcta tttcggctgg aatatgtctc
    25561 gcaacttctg ttcgatacga agttgctcct gcaccaactg gatcaaatag tactggcaca
    25621 ttgttcacat ttgctgattt accagcaagt aacatcgctt ctacttcctc aggacgaagt
    25681 gttcccatat ttaatactaa cgctccagca atgctagcca tttctgctac ttcttctttt
    25741 gcatacgcca ttacaggcga tgccccaagt gccaacaaac cgttagcagt aaaatttgtt
    25801 acaacaacat ttgtaatatt atgaacaagc ggattagatt ctctcaccaa atccactact
    25861 ttactaattt ctttcatatt catccttttc atctcctaac tataatgatg ggagatacac
    25921 aaaaagacac tttgcgcgta cgcaaagtgc ctgaacatgt gcttttacac tctccctacg
    25981 ctggcattat ccaacaggtt caaatggtca atgacggact agtagccata ctctcagttt
    26041 gtatccacaa actcccatgt gtttcttatt catctacttc aaagtctact cttattctag
    26101 taaaataaca agttctttac ttttctattt aatatagaag caactgataa agtgaaactt
    26161 taatcagttg ggattttgtt cactccatta aaaacagctc aaatatggag cgaaactgaa
    26221 tctcaagaag atgtatgcta tatttaactt atggaaattt gaaaggatgt ttttaatatg
    26281 tcaaaaagcg ttgtaatcgc tgaaaaacct tccgttgcac gagatattgc tcgtgtactg
    26341 aagtgtgata aaaaaggaaa cggctatctt gagggtaata aatatattgt aacttgggct
    26401 ttaggtcatc tcgttacatt agcagatcca gaaagttatg atatgaaata taaaaagtgg
    26461 aatttagaag atttaccgat gctacctaag cgtttgaaat taacggttat taaacaaact
    26521 ggtaaacagt ttaatgctgt aaagagtcag ctacttagaa aagatgtaaa tgaaattatt
    26581 gtagcaacag acgctggacg tgaaggggaa ttagtcgcac gctggattat cgataaagtt
    26641 aagctaaata aaccaatcaa acgtttatgg atttcttctg taaccgataa agcaattaaa
    26701 gatggttttg caaatttaaa accaggtaaa gcctatgaca atttatacgc ttcagcagtt
    26761 gcacgttcag aagctgactg gtatatcggt cttaatgcaa ctcgcgcttt aacaactcgc
    26821 tttaatgccc agttaaattg cggccgtgtg caaactccta ctgttgcaat gatcgctagt
    26881 cgtgaggatg aaataaagaa cttcaaagca caaacttact acggcatcga agctcaaaca
    26941 atggagaaac tcaaacttac ttggcaagat acaaatggca atagccgtag ttttaataaa
    27001 gaaaaaattg atggtattgt aagaggttta gataaacaaa atgctaccgt tgtggaaatt
    27061 gataagaaac agaagaagtc attctctcct ggtctttatg atttaactga attgcaacgt
    27121 gatgcaaata aaaagttcgg ttactctgct aaagaaacat taaatattat gcagaaattg
    27181 tatgaacagc ataaagtgct aacgtaccct cgtacagatt cacgctacat ttcatctgat
    27241 atcgttggaa cacttccaga acgtctaaaa gcatgtggtg ttggagaata ccgtcccttc
    27301 gcacataaag tattacaaaa gcctatcaaa cctaacaaat catttgttga tgatagtaaa
    27361 gtaagcgatc atcatgcgat tattccaaca gaaggatacg ttaacttctc agcattcaca
    27421 gataaagaac gcaaaattta tgatttagtt gtaaaacgtt tcttagctgt tttattccca
    27481 gcattcgaat acgagcaact aacattacgt accaaagttg gtagtgaaac gttcattgca
    27541 cgcggaaaaa cgattttaca tgctggttgg aaggaagtat acgaaaatcg atttgaagac
    27601 gatgatgtaa ctgatgacgt aaaagagcag cttctgcctc acattgaaaa gggcgataca
    27661 ttaactgtaa agttacttat gcaaacatca ggccaaacga aagcacctgc acgctttaat
    27721 gaagcaactt tactttcagc aatggagaat cctacaaaat atatggatac gcaaaataaa
    27781 caactcgctg atacattaaa atcgactggt ggattaggta ctgtagcaac gcgtgctgat
    27841 attatcgaca agctattcaa ttcgttctta attgaaaaac gtggcaaaga tattcatatt
    27901 acttcaaaag gccgtcagtt acttgattta gtaccagaag agttaaaatc ccctacacta
    27961 actggtgaat gggaacaaaa acttgaggct atcgcaaaag gtaagctgaa aaaagaagta
    28021 ttcatttctg aaatgaagaa ctatacgaaa gaaattgttt ctgaaattaa atcgagtgat
    28081 aaaaaatata aacatgacaa catttcaacg aagtcttgtc cagactgcgg taaaccaatg
    28141 ctagaagtaa acggcaaaaa gggaaaaatg ctcgtatgcc aagatcgtga atgtggtcat
    28201 cgtaaaaatg tatctcgtac aacaaacgct cgctgtccgc aatgtaagaa gaaactagaa
    28261 ttacgtggtg aaggcgctgg ccaaattttc gcatgtaaat gtggctatcg cgaaaaactt
    28321 tctacattcc aagaaagacg taaaaaagaa tctggaaaca aagctgataa gcgcgacgtt
    28381 caaaaatata tgaaacaaca gaacaaagag gaagaaccat taaacaaccc atttgcggaa
    28441 gcattaaaaa aattaaagtt cgattaaaca aaaaggttcc taccgctctc ggtaggaacc
    28501 ttttcttaat gaatgatttt acttcctttt gcattctcaa caaatttttc acttgatttg
    28561 ttaattggtg ttttcagtaa taacgcagca acaatcataa ctactacgaa agcacttaac
    28621 acaagtaaat cgcgcgttac gatatcccaa agcattccgc caactgtttc acgaattgcg
    28681 ctaattgcgt atgtgaatgg taagaacgga taaatcgctt ggaagaacgc tggtgtcatt
    28741 tggattggga atgttccgcc cgatcctgct acttgtagta caagtaaaat gatcgccatc
    28801 gatttcccaa catttccgaa aatagaaacg agtgagtata cgatacaaac gaagactcct
    28861 ccaataaata aactaaataa cacaaaccag aacttatcga ctacgtacgt accgagtaag
    28921 aatatatctc ccatcgatac gataaacgct tgtgaaagac ctatcgttaa gaatgttaat
    28981 aaacgtccga agtaaatttc atggctctta taatttgcgc cctcttcgtg tacttctacc
    29041 gttaataatg aaaccattaa taatgcgcct acccataatg caagcactgt atagaatggt
    29101 gacatcgctg aaccgtagtt cggcatcgca aataatttat tttcttttaa atttactgga
    29161 ttcgcaaagt aatcactttg cttctcaaca tcgtttttca ataagcgtat gatgtctttt
    29221 aaatcctctt cagattcaaa atcacgaatt ttatctgcta attctttaat ctttttctca
    29281 gtagctggca tttcagcttt aatgtctgct aatttctttt taccatctac taaacctttt
    29341 gatgaatctt ctagtaattt tttaacatct ggaagctttt tgtctgcatc gtttaaaatt
    29401 tgagttgtat ttttcgacat ctcttttgta cgagcaattg ctgtattgaa gttaggtaca
    29461 atctctgaat catacgtcga taatacatct gttaattgag ctgatccgcc cttcgcagca
    29521 ttgttaatac tttcaattac atcttttgta ggtttctgtc cattgttaag aagtgtaatc
    29581 cccttattcg ttgcatctac acctttttgc agactacttt tcgctttatt taattttgcg
    29641 attccattat taaggttttt atcactattt acatccgcta aaaccttatt tgtactttct
    29701 agaactggaa tcatatcatc aattaaaccg attccagatt ggaattgacc atttaagctt
    29761 ttcaaggctt ccttcgaacc ttctaaacca ttaatacctt tgttttgtac atcctctagt
    29821 gctttttgga cactagattt agtactttct agaccatttt tcgctttatc ataatcagct
    29881 tttgcattat cgtatatttc attcgcatta gctttagctt gatctactgt gctaactgct
    29941 tttttataat ctgctacaaa cgtttcatta taatcttttt cagcttgatc aattaatgca
    30001 tttgctgcat ctaatttttg atttgctaca tctgttacat ctttctttac ttcttgtcct
    30061 gtaccgataa catttacaat atctttaata ccgttgtttg cattttccat accacttttc
    30121 agcttagtta ggcgatccac tcgcccttgg aaaaagcttt ttccaaaatc agtcgtcgct
    30181 gagttttgaa gttcagtaaa tacattaata agatacgaaa taccttctgt acgagcttgc
    30241 aattgatttg atactgcatt taaatctttc tttgcttgtt ctggatcaaa ctgaccattt
    30301 tgcaatccat ttaaaacact tttcccataa gctgttcctg cacgtgatga gcttaaaaca
    30361 ttatttactg tttgattaat attttgcgct atacttttat atccgtcatt attcaactta
    30421 gaaaggtccg gtcttgcagg gaattcaggt aatccattca ttccagagaa atcaggaata
    30481 tttaaatcca cacctggatt cattaaaaag ttagtaaata cagctgcact atccataacg
    30541 ccttttgcta ctactaaatc atttcttatc gttcctggag cgttttttaa tgtttgatct
    30601 tgtcttgcaa agaacttatc taaattcgcc aatgcttcct gcccatcatt tattacactc
    30661 tctacaacag gtaaatcttt ttgcgccact ttcacaatat cttctgctcg agtcgcatca
    30721 tctaacgcct tatccatgag tgtattcatt tctgggaact gcgcttctaa cttaaataca
    30781 agatctttta ctttttcgat acttggtaag tttgtttcta aatcgattcc aaggtcattg
    30841 aaaattttaa aaatctcacc gtttgctgtt ttaacaaagt ttttactaat ttcttctgta
    30901 atacctgatg caccttttgc tgtaatcttc ggtgcgatcg cgtttacttt ttcattcaca
    30961 tagtaatcca gttctggttt tttcggattt tcatccagaa cagttgcgat tttttcagag
    31021 aagtcttttg gaatcgtaat acttgcataa taatccccac gctcaactcc gtaaattgct
    31081 tgtttttcat ctacaaattt ccagccaaga tttttgtttt tcttaaggga gtctacaatc
    31141 tctttcccga tattaatatc tttccctctt aaattagaac ctgcatcttg gttagaaact
    31201 gcaatgggaa cctcttttgt atttccatac ggatcccaag aagctttaat gttaaaccat
    31261 gcatataacg atggtaaaat cattaatcct aaaacaataa caattgcagc ccaatgtttg
    31321 gctacattcc gtaaatctgt cttataaata cgccaaatct gtttcataga agttatcacc
    31381 taattatata tttttccttc tttagaaaat gatacatgca ttttgcaatt atatcacttt
    31441 ctacatcgtg tattaaccaa aaacgtacta ttttttccca ttaactttca cttacttcat
    31501 tatataacga agtgagtcaa agtatgaata caaaatgacc aaatcggttt tacattcaat
    31561 aataacaaat atatatgaaa tgtcataaaa aatacaagta ttttctcttg gaaatacttg
    31621 tattcctaaa aaaatcctca cagcttttat tctctgtgag gatttcttct attatatatc
    31681 caattgaacc tctacaccga aatgatctga aattacattt ctgtttgtac cattaaaaat
    31741 aacttttgaa gaatgaactt ttttactttg gttacacaat attagatcga ttcgcaaatt
    31801 atgtttattt tcatcccaac cagcaatctc gccttggaca gtcgttcctt catccttctc
    31861 tattgctaat tcatatgtgt catacaaccc tttttgcatc atatactcat aaccttcgcc
    31921 ttccaagcga gcattgttat taaaatctcc cattaagaag gcgagcttat tactatctac
    31981 acgccccatc aaacgatcaa cttgaccttt gaatgactct tcttcatcat tccaccaacc
    32041 gagatggcaa gagtaaaacg ttatatcttt accattataa gcaattgttg tacttacaat
    32101 tttacgcgtt ttccaatacg ttgtatcctc gttttctgaa ataaagaacg tatcttcttt
    32161 tataatatta tgcttcgtta taatcgctaa cccttcttca tacacgtcat aaccaatatg
    32221 agagaaatcc caagtaatat tgtaatcttt tacatgtagc gcttttaact cttctaatag
    32281 taaaagtcca aaattatctt ctttcttgtt accgcataca ttttcagctt gtatggactg
    32341 acttacttct tgcaatgcga tgacatcgta ctcttcttct tgaattactt tagcaaggta
    32401 ttgtatcttt tctatttgat tctcttcttg ccaagaatga cagtttaaag ttagcaattt
    32461 catattatta cgcacctaac atatcttgaa tgtctgactt taatacgtca gctttcggac
    32521 catataccgc ttgtacacct ttatctttta caataagccc taaagcacca ttttgtttcc
    32581 actgtgcttc tggtgcaaca acatctaagt cttttactgt tacacgtaag cgtgtcatac
    32641 aagcatctac gtcagcaata ttttcttttc cacctaataa atcgataact tttgttgcta
    32701 atgaaccatc ttgtacattt cctgttcctt ctgatgcctc atcttcatta tcaatatagt
    32761 tacctgcacg ccctggtgtt ggtaagttga attttttaat taagaaatta aatagtgtaa
    32821 agttaagacc gaagaacact aatgaaacaa taacaaagtt gattaagtct cttgttaaac
    32881 ctgcgttaac catcattggt gtacgagtaa ttaactcaat aaatccaaat gcatgaacac
    32941 gtaagttaat taaatcagct aacgcgaatg caagtcctgt tgtaatagca tatacaacat
    33001 ataatactgg agcaataaac atgaacatga attcaattgg ttctgttaca cctgttaaga
    33061 atactgctaa tgctgctgat aaaaacattg gtttatattt tgcacgcttt tctttatcaa
    33121 cgttacggaa catcgcaaat gcaatcccca ttaacgctgc tgttgagccg ataacttgtc
    33181 cagctttgaa acgagctggt acaacgttat ttaataaatc gttatatgcc ttcgtatctc
    33241 catttgccaa taaattattt aaatctgtaa tccatgcaag ccataatgga tcttgtcctg
    33301 ctacaacttg tccaactttt gaaccagtta gcatcgtata tgttccgcct agctctgtat
    33361 agttcatcgg aatcgttaac atatggtgta aaccaaatgg taataataaa cgctctaacg
    33421 ttccatatac aaacggtgca acaactggtg cactatcttt tgaagctgca atccagcgac
    33481 caaattcatt taacccactt tggatgaatg gccatagaag tgataataca atcgcagtaa
    33541 ctgtagacca aagaattaca acgaatggta caaatcgttt tccattaaag aatgctaatg
    33601 cctgtggcag tttattatag ttataatatt tgttatataa agtagctcct aagaaacctg
    33661 tgatgatccc tacgaacact cccatgttta atgcaggtgc accaagtaca gaagtaaagt
    33721 aatcttttac aattaaatct cccgctatta ctgaagaaac tttcgctttt gaatccgcta
    33781 acatttcagc gtttacccca aatatagctc ctgtaattcg gtttgttaag acgaatgcta
    33841 atagcgctgc aaatgcacca cccgcgcgat ctttcgccca agatccccca attgctactg
    33901 cgaataggat gtgtagattt gtaatgattg cccaaccgat gtcttccatt acgcgagcga
    33961 ttgtatgaac tgcgttaaca tccccagcag acataccaat taacttaccg atggaaatca
    34021 ttaaaccagc tgctggcatt acagctacaa caactaataa cgctttcccg aacttttgcc
    34081 aaaaatcaaa agacgtaatt ttcatctgtt cttcctcccc tttatttata acaacataat
    34141 gatttaaatt ataatttctg ttccctttat gaaaacgatt ccttatatta ctttattttt
    34201 atctttacgc aaccgttttc ataaatctat tttaataaaa gcgttttcac tttgcaatag
    34261 aaatttattt tttttcataa aaaaagatgc tcaaagagca tcctttttta ttatgaaatg
    34321 cgataaaccc ttgtttcata aggttttaaa gcaattgttg ttacttcttc atgttccgca
    34381 acttcatagt tatttaaaag caaacgtttg cgttctagtg caaatgaacc ctcattatac
    34441 acagcttcct cttttgagat attactaatt acaatgactt tttcatcctg taacgtacgt
    34501 gtatatgcat aaatttgtgg atcgtcttct aaaagtaaat cgtacgtacc atagttcagt
    34561 acatcgtgct cttttttcag ggcaatcatt ttcttataga aattgaaaat agacttttct
    34621 tcattttttt gcttttcaac attaatttct ttgtaatttg gattcatgct aaaccaaggt
    34681 gtacttgttg tgaaaccagc attcatctca tcattccact gcataggtgt acgtgaatta
    34741 tcgcggcaag aagcccatat aatctccatc atatcttgat gtggtacgcc ctctgcaatt
    34801 ttctcgcgat ataaattttt aattgctaca tcatcgtaat cttcaatatt tggtaactga
    34861 acatttgtca taccaatttc ttggccttga taaataaacg gtgtaccgtg cataaagaaa
    34921 tacatcgccc ctagagctgt tgcactttca cgccaatatt gtttgtcatc tccccatgtt
    34981 gaaacgatac gtggtttatc gtgattctca atatataaag cgttccatcc tttattttct
    35041 aatccttttt gccatttcgt taatactttt ttcaatccta caacatcaag gtctttcttc
    35101 ttctctgcat cccataaact taaatgttca aactggaata ccatattgaa cttaccttgc
    35161 tcttctccaa cccaaagctc agcatcttca atcttaacgc catttgcttc accaacagtc
    35221 ataatatcgt acttagagaa tgtattttct tttagctctt ctaataaagg ttgaatacct
    35281 ttcacattca tatgtttatc aaaagatggc acatatttta actcttttgg atttggcata
    35341 tccttaaagc cttcttcttt tttaatatga ctgattgcat caacgcggaa accatcaata
    35401 cctttatcaa gccaccaatt aaccgtatca tatagtactt cgcgaacttc tttattctcc
    35461 cagttcaaat ctggttgttt acgtgagaat agatgtaaat aatattgttc tgtttcttca
    35521 tcatattccc atgccgaacc attaaaaata ctttcccagt tgtttggctc cgcaccatct
    35581 ttaccatcat gccaaatata ccaatcacgc ttcggattat ctttagatga acgtgattca
    35641 ataaaccatg gatgttcatc actcgtatga ttaataacta aatcaataat tagcttcata
    35701 tcacgcttat gaacttcatc tagtaaagca tcaaagtctg ccattgtacc aaactcatcc
    35761 ataatatctt gataatcact aatatcataa ccattatcat cattaggcga tttatacatt
    35821 ggacaaatcc aaattacatc tatacctaag tcttttaaat aatccagttt tgcaataata
    35881 ccttgtaaat ctccaatacc atcaccattt gaatccataa agcttcgtgg ataaatttga
    35941 taagcaaccg cttctttcca ccatgtctta ttcatagtca ttctctcctt ttgcatccca
    36001 tcggaatttt atgcaaacgt tttcgtaaca ctatcataac aaaatatgaa cagtttgcaa
    36061 ctgttttcat tgaactctat gtagattctt tattcttatg ctttatttat ttctcacaaa
    36121 ggtaaatctc attcttcacc tctccttgtc cacgcgtatt acagacattt ttcatatatt
    36181 aataaaaagc tctgattatt ttggaaagga gtaagaaatt gaagcaaaca aaattaacag
    36241 gtcgtatcgt tgttcccaca gatcctgact acaatgtagc ccgaatgaat ttaaatttaa
    36301 gtattccaaa actcccttgt attattgttt tttgtcaaaa taacaaggat atctgtaacg
    36361 ccttaaaatg ggcacgtgaa cgtcatatac catttcggtt aagaagtgga cgtcatagct
    36421 atgaaaattt ttctctttta aatagaggac ttattattga tgtgagtgaa atgcatcgca
    36481 ttactgttaa tacagagaaa ttaacagcaa caattgaggc tggtgcaaat cttggcactg
    36541 tttataaaga actttggaat tacggtgtta caattcctgc tggtacaagt gcaagcgttg
    36601 gaattgttgg attagcactt ggcggtggta ttggtatgct ttcacgctta tttggattaa
    36661 catgtgatca attaatggaa gtggaaatgg tacaagcgtg tggaaaattt ggtgcaaaac
    36721 ccattcgtgc aaatgaacaa gaaaactcta accttttttg ggcatgccgt ggtggcggtg
    36781 gtggaaactt cggaattatc acttccttaa cttttcgagt ccaccccgta aaaaatgtat
    36841 caattttctc aattacatgg gaatgggaag actttattgc tgcatttcaa gcgtggcaaa
    36901 actgggcacc ttatatagat gaacgtctca cttcatcgat cgaattattc gccaagcaac
    36961 gaaataaaat cgaagcacaa ggcgagtttg tcggttctcc ctctgaactc cattccctat
    37021 tatcccctct tcttgaaact ggcagcccct ctctctttat agaagaagtt ccttatataa
    37081 aggctgtcga attttttaat ggcggtaaca tccctgaaaa tttcaagcgc tctggttcct
    37141 atgtctataa acctattccc cttaaaggca ttcaactcat gcaatacttt ctttctcatg
    37201 ccccaaataa agatgctagt atttggcatc aatcgctcat aggtgctgtt gaaaatattt
    37261 cgccgaatga aacggcttat tttcatcgta aagcaattat tgcccaagaa tacattacct
    37321 cttggaaatg cgatgatgaa gaaaatcgaa atatacgctg ggttaaagat ttacgagaaa
    37381 gcttagatcc ttatacacta ggtgactatg tgaactggcc cgatatcgac attaaaaatt
    37441 ggcaaactag ttattatggc tctaactttc acagattgcg taaagtaaaa actatgtatg
    37501 atccttgtga tgtttttcat ttccaacaaa gtattcctcc ttttcatacg tgaaaaagag
    37561 gataacataa aaaaatcatc caatataccg ttacctcaca gtatgttgga tgattcaagt
    37621 tgattttcta tatcgtttca aattcttgct cctactcata aacttttact tacagattaa
    37681 ttgtatttcg tatcattttc atgcaatgaa tgtaatttaa tatttggtac tttatctttt
    37741 tccatacctc tattataaga aacaggaact tgaaattcga attgctttgt ctcatgtttt
    37801 tgtaaataga ctggtttcgg tactggatag ctttttgaat tctcgtttgc attatcatat
    37861 aaaacaactt ttaatgcttg tgaatgatta cgataatttt ttaaagtaac aatgcacttc
    37921 ggttggatat tatctccatt tttctccatt ctacactggc tatcttcttt tttatattct
    37981 attgcttcta cccctgtttt tcctgcatag taccatgttt tattcaatgt ctggaggatt
    38041 gtatttaaaa taaacggcat cattacaatc aaaatactaa tgcctactac ttttatctta
    38101 ttcatttttc taaatgtact agactccttt tttcctagcc attttaaaaa taatataaat
    38161 gcaattacat gtagtatgaa agaaacaatc aatatatttg agactttata atccatataa
    38221 acatacgtat gtatcggaac cttatagaca ttgaatagtt tttccccaat taattcatta
    38281 tcatttggaa tttttaataa taacaaaacc cctatactgt aacaaatagc tactaatcga
    38341 tcatactcaa tacgaatcat tctttctccc cttcactttg ttttttatta tcgattttag
    38401 ctattattac catactatac aatcttttta tagaggataa cgtaaaaaag ttccttataa
    38461 atatataaag aaccttatta atatacatta tgaattaaaa aatcaatata caattttcac
    38521 attgagattt cttcaaaata tgttggattg tgtattgtaa tttttttatc taaaattgta
    38581 acaatgctat cattttttaa ttgttttaat acgctgctaa ctgtctctcg agatgttcca
    38641 gatattttgg atatttcaat tgttgtaagt ggacatgaaa ttacaatctt ttccccactc
    38701 tgttctccta aatcctgcat taaataattt aacgtttgga taacacgatc ttgtgcatta
    38761 ggaattgtaa tattttgcac tcgattttca ttcaatttta atatagatga taattgctga
    38821 acaacgtaca tcaattgcgt tctgctggat tttaccatat cttcaaagat taccgttgga
    38881 atataatata cctccacatc cgtcattgct tctgctgtat agttatatcc tctgtctgta
    38941 aacataccac cataaggaaa aatagaatac cgctttacat agtcatcgta taataagttc
    39001 ccattttgat taacccgctc taactttaca aaaccatcta acatgaagta aattctttcc
    39061 cttgaatccc cttctaaaaa taaaaattga ccttttttat aagttcgcca ataaacaaac
    39121 tctgttaagc ctttcaattt tttttctgtt aaatgagcaa ataattcgaa ctgctttaag
    39181 tctttcacta cgttccgtct attcataaaa ttccctctct cttgctgtat gttggagcga
    39241 aaaatcaaga aagcgtattc aatttgaatt ttatcataat taacttatat attcagattt
    39301 catcatgaaa actttatgaa caatgagtac aaaaaatatt aataaataaa aagaatgaag
    39361 ttattaacct cattcttttt tttactacta agtagcgtac ataataattt aaacatacat
    39421 gcatacattc tgttttgaaa taatagtacc agctttttct tctagtgctt catatacttt
    39481 ttctaaagac gtaataattg tttttctttt tggatttgta ttaacaaaat taatagcagc
    39541 ttcaattttt ggaagcatgc ttcccgcagc aaattgttgt tcttcaatat attcttctaa
    39601 ttgattcact gtgacatgct ctaatttttt ttgattcggt tgattataat ttacatacac
    39661 atgatcaact gcagttaaaa taacgagcgt atcggcatct actaattctg ctaatttctg
    39721 cgcagcgaaa tctttatcga taaccgcttc agttcctttt aacccttctt cggaatcaat
    39781 tactggaatt ccacccccgc caacagctat cactatgttt ccatcttcca ccaaagaatt
    39841 aatcacttta tgttcatgaa tacttacagg cttcggtgat ggaacaacac gtctccatcc
    39901 tctaccagca tcttctttaa acactgcttt tgtttcatcc attaatcttc tggcctcttc
    39961 ttctgtataa aaaggaccaa ttggtttagt tggattttta aatgcctcat cttttttgtc
    40021 cacaacaacg cgcgttataa ccgttgctac atctttttgt atattccgtt tttttaatgc
    40081 cttttcaatc gcattttcca tccaatatcc aatcatccct tggctcattg ccccacaagt
    40141 atctaatggc attgcaggtg tcttttccgt ttctgcagct ttttgctgta ataaaatatt
    40201 ccccacttgt gggccatttc catgcgcaat tactatatcc acatcatttt ccattatttt
    40261 cacaagttgt tccgccgttt tttccaacgc ttcttgctgc gctcccgcag tagcttctcc
    40321 agactgtatc gcatttcccc ctagtgcaac tacaattttt cttcgtgcca tatttcagcc
    40381 ctccagttca tttcgctttc acagcgcttt ataaagtaat actgcctgta attaatccat
    40441 aaatcgcaaa gaatgctaaa gcaccaattg ctacggatga tgctaattcc actcgagtaa
    40501 atatttgctt cgaactcttt tgcttttgaa cattgtaaaa aataaaaata cctggcgcat
    40561 ataaagtcat tgttaataat aaatactcta a
//
