LOCUS       NZ_PVRL01000014        25471 bp    DNA     linear   CON 21-MAY-2024
DEFINITION  Bacillus thuringiensis strain NMTD81
            NODE_14_length_138570_cov_16.9793, whole genome shotgun sequence.
ACCESSION   NZ_PVRL01000014
VERSION     NZ_PVRL01000014.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis
  ORGANISM  Bacillus thuringiensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 138570)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., W,H. and Gao,X.
  TITLE     Genotypic and phenotypic analysis of antagonistic Bacillus spp.
            isolated from rhizosphere soil of plants in Tibet
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 138570)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., W,H. and Gao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) UG, NordReet, Marienstr. 27a, Greifswald
            17489, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. A5-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 14.5x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002998815.1-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 01:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,177
            CDSs (total)                      :: 6,068
            Genes (coding)                    :: 5,840
            CDSs (with protein)               :: 5,840
            Genes (RNA)                       :: 109
            rRNAs                             :: 11, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 1 (5S, 23S)
            partial rRNAs                     :: 6, 5 (16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 228
            CDSs (without protein)            :: 228
            Pseudo Genes (ambiguous residues) :: 0 of 228
            Pseudo Genes (frameshifted)       :: 100 of 228
            Pseudo Genes (incomplete)         :: 142 of 228
            Pseudo Genes (internal stop)      :: 67 of 228
            Pseudo Genes (multiple problems)  :: 63 of 228
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:59:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 71544
            Orig. end                         :: 97015
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVRL01000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25471
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="2"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25471
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25471
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15471](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15471)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(1320..2366)
                     /locus_tag="C6351_RS33290"
                     /old_locus_tag="C6351_24570"
     CDS             complement(1320..2366)
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014048.4"
                     /locus_tag="C6351_RS33290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24570"
                     /product="endonuclease NucS domain-containing protein"
                     /protein_id="WP_346725880.1"
                     /transl_table=11
                     /translation="MNVIILFILLAGGGVMDALYLNRKEKLIDKDRLLERYGCVRVEYR
                     ELEDQRYYLYAFSNSLEEWDFNNGELIGIVTDKDIIKYLKKNILTIESGEFFCKECFRK
                     KDIAKLSNSTETKYWCFYIWEGTPYNAKQRMQNEILFTITEMDWSMVKDATNSVKPYIF
                     YGICSDNCMTNDQYNCDEKIKSIRRSIQSIWELCITDAIMEGTEELLELFLCEYTECIE
                     EGMEFIANQHRVEGGIIDILAKDKNGVLCVIELKVVEDDKNIAWQSAYYPSCFNEEVRI
                     ITIAPNYSNRIYYALRNVSNVEIKIFEKDENGLFNIKDFEVEPTESKLTQLEEIEKNYE
                     NEVSKDGF"
     gene            complement(<2376..3008)
                     /locus_tag="C6351_RS24565"
                     /old_locus_tag="C6351_24575"
                     /pseudo=""
     CDS             complement(<2376..3008)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028472.1"
                     /locus_tag="C6351_RS24565"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24575"
                     /product="IS4 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNLSILDELQPIAEELQRHMSPLTLEHLAKEKGFVQRKSKYQAQE
                     LVALCVWLSQRVASTSLTQLCSCLEVSTGVLISSEGLNQRFNASAVQFLEQILANLLTQ
                     RIHSKKEIIHQYTTTFKRIRILDSTTFQLPDKFSSHYQGSGGSSHTAGVKIQLEYDLLS
                     GKFLHVYVGEGRENDKTFGSTNLQTIQPKELYIRDLSFIEIGYIIKNV"
     gene            complement(3638..4342)
                     /locus_tag="C6351_RS24575"
                     /old_locus_tag="C6351_24585"
     CDS             complement(3638..4342)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448835.1"
                     /locus_tag="C6351_RS24575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24585"
                     /product="DUF4352 domain-containing protein"
                     /protein_id="WP_098355555.1"
                     /transl_table=11
                     /translation="METLAVLIFLASIVLFVLFIIALFKRKPKAKLFISSIVCLVLAMI
                     LIPTKDKEEKPKAKETTQQASTEVKEEPKKEEVKKEEPKKKEEPKKEEPKKEEPKKELS
                     KEGESSKVKIAVGSVESTDSVGGQYLNEKAQGVFKVVEISITNNQKDAITVDANSFKLV
                     DNQDREFKYSAQAQTAFDVGNGGKSDFFLKQLNPGLTQTGKIIFDVPADAQGLVLKARG
                     GMMGKEIKLKVV"
     gene            4542..5213
                     /locus_tag="C6351_RS24580"
                     /old_locus_tag="C6351_24590"
     CDS             4542..5213
                     /GO_component="GO:0043592 - exosporium [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087351.1"
                     /locus_tag="C6351_RS24580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24590"
                     /product="exosporium leader peptide-containing protein"
                     /protein_id="WP_106082231.1"
                     /transl_table=11
                     /translation="MNEKNEFLSGAAFDPNLLGPTLPPIPVFTLPTGPTGPTGITGVTG
                     PTGATGITGPTGPTGATGPTGIGATGPQGLPGPTGPTGTTGSNAPSINFRAEKAPVQDY
                     SSSDFLQVSFESIVFNNGGGYSSITNTFTAPIDGIYLFTVNLAFSTTSLPAEVSLEIRK
                     NNLPISVDTETFNITSLPFINNTTIINLVAGQNIAVFFSSSQSGALTETPVAYFSGTIL
                     P"
     gene            complement(5305..5667)
                     /locus_tag="C6351_RS24585"
                     /old_locus_tag="C6351_24595"
     CDS             complement(5305..5667)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001259509.1"
                     /locus_tag="C6351_RS24585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24595"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_106082232.1"
                     /transl_table=11
                     /translation="MENTVGQNIKQLRKSFDLTQEQLSERTGLSRGQIKNWETDRHEPD
                     LESLKVLASFFNTSTDALLNFENRKEDALLGLLFNDIQRAYEELDGRQQGRFAKQVSLY
                     VKMLQKKRIYCDLISS"
     misc_feature    5769..5782
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.17"
                     /tool="antismash"
     gene            complement(5927..7357)
                     /locus_tag="C6351_RS24590"
                     /old_locus_tag="C6351_24600"
                     /pseudo=""
     CDS             complement(5927..7357)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028482.1"
                     /locus_tag="C6351_RS24590"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24600"
                     /product="IS4 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSISVANELQLFSQEIQSLLSPNTLQNLARDVGFVQRTSKYQAQD
                     LVALCVWVSQSVAKTSLT"
     gene            complement(7543..9405)
                     /locus_tag="C6351_RS24595"
                     /old_locus_tag="C6351_24605"
     CDS             complement(7543..9405)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139450.1"
                     /locus_tag="C6351_RS24595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24605"
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_106082233.1"
                     /transl_table=11
                     /translation="MPSKNRNYFNPCEFPYSLFPCAFPCAVPEPIKPIDPTKFDYIVIG
                     AGTAGGVIAKELTDDKSTSVLVLEAGTNMTNELSNPSVLAAINTTRGNRFSFNVTSELE
                     STIARTLIATNGRAIGGSSEISDMYAVRGSKELYNQWASLVGNQWSYDKISSLFVKNET
                     YTGSTQDPDERGSQGPIFIRQQSIPPSGLINTLVQATNTVLGTPIAVDYNTGIRDCTFY
                     KSQIIQKEISPGQFVRSSTATGYLNDHIVSQGNQFHPDEFGVGGRKLVILAKTTVNKIL
                     FKKKNGLNIAVGVEFVKDGVSHRRFARKGIIVSAGFFSSVILQRSGIGKSDDLAKAGIP
                     TFIESPNVGHNLQTHGYVGLGVEIDTSQILPIFFADPNFPLILGAFQAENPMNLLESRR
                     LQLIGAPIPFFIPAPDVISNGWSLDLTFQTTPSIMSFGIVDVNTKSRGTVLVEHSDPEA
                     YPSLNFNPLEDPNDLTYMVDQYKRIYNIIVEARDPLKYPNNGIGKVVYPPESIFELPNN
                     DPNKQQQLENYVKASYTNFSLGGQCRMGQTIQEGVVDGFLNVFGTKNLKVADLSISPII
                     PDGQPSAAAQMIGLNAVRFIKEDPSPYVMTDKELEDYENEIKII"
     misc_feature    complement(9490..9503)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(10001..10384)
                     /locus_tag="C6351_RS24600"
                     /old_locus_tag="C6351_24610"
     CDS             complement(10001..10384)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (83-94). E-value:
                     0.00064. Score: 11.2. Matches aSDomain:
                     nrpspksdomains_C6351_RS24600_PKS_Docking_Nterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="C6351_RS24600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24610"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_142399150.1"
                     /sec_met_domain="LANC_like (E-value: 4.4e-09, bitscore:
                     28.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVQGQEFFLIQNQRLKEKVQDVIFSTAKIFKSVSKIDSIIMADED
                     RELKELKSNSLISGYPGICLLLGVLDNIDPDGEWDILALEYLKRVQADLPSSLFHGLAG
                     IMMNVEACSRNKSRYFKQGYLYN"
     aSDomain        complement(10103..10135)
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS24600_PKS_Docking_Nterm.
                     1"
                     /evalue="6.40E-04"
                     /label="C6351_RS24600_PKS_Docking_Nterm.1"
                     /locus_tag="C6351_RS24600"
                     /protein_end="94"
                     /protein_start="83"
                     /score="11.2"
                     /tool="antismash"
                     /translation="LEYLKRVQADL"
     gene            complement(10445..12271)
                     /locus_tag="C6351_RS24605"
                     /old_locus_tag="C6351_24615"
     CDS             complement(10445..12271)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016113476.1"
                     /locus_tag="C6351_RS24605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24615"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_098355710.1"
                     /transl_table=11
                     /translation="MNWNTNLSLREILGSFKYWPKIFKLLWKVDKKLIIFIMLLNIMAG
                     IFPALLLLGNQFLINSIVIGWEQGLNIVLNSLVILISIYLLQLLIGQFLNYYEAIYKVK
                     LSYSVNVILMEKSSMLTLADFENDVIYDQLQRAQREVDYRPYQIFNQILSIINSFVTLI
                     STATILIAWKWWVVIILLIVPFFSSISFLKLGRKEFDIEWERAPLNRKLWYLSYLLTKD
                     ATFKEIKLNNLGAHIIKEYSGIYKDFFQVDKSIEKRRLKITFIYDFINLIVVGILIFII
                     LLSTFIKEILIGTMVSYIQALFATQKASQSLLHQIFSLYESNLYIEQLFSYLDVEENDN
                     SKCSVNELSEIESIEFKNVSFKYPNNETYALKNISFTFRKGDIVAIIGKNGSGKSTLVK
                     VLTRLYHGYEGEILINSQPLNSYSIESVREQIGVVFQDFVKYELPVRNNISYGNIGYIN
                     DDEKINNAALQSGIHEVIKSLPNKLDTQLGKWFSEGYQLSGGQWQKIAISRAIIKNASM
                     YILDEPSSALDPEAEKDVFNRFKELVQNRIGIFISHRNSSVQFANKIILMENGEIKECG
                     NHEKLMDEKGVYAKLYYMQAEVYSKGSKMQVH"
     gene            complement(12268..15471)
                     /locus_tag="C6351_RS24610"
                     /old_locus_tag="C6351_24620"
     CDS             complement(12268..15471)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016113475.1"
                     /locus_tag="C6351_RS24610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24620"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_106082234.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.3e-169,
                     bitscore: 557.5, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.3e-12,
                     bitscore: 41.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 8.5e-37, bitscore:
                     120.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKEKKNSIIKSTNLFEPLNFFMVRSPMLSLNFYKDLFENTNGEK
                     VELEQMMKKLETKISDPIIQEAIFVSSSSLYNSIIDLNHISNKKRREQIIHAVNKYLIR
                     MSTRPTPFGLFAGVTYGTFDSFTSFSIEKPLFHKKQTRPDMSWLLALIHKLESNIFVMK
                     QLKVQVNSIILAKGERINVPYSSRTEAFQGNLFNFESSSIRMTPVVQLILELAKKPIKI
                     DEIIFALKQKYTNVLEEKIHVVLLQLIEREYLVTELSPSLMIESPFEFLIEKLEHVQGI
                     EELKIDLKQLNQLITYYDQKYIGEGLHVVKEINQQMKKIIATKDNIQIDVRLEDKDICL
                     SKSVGEEVANVASVLWKLSLQYSQKQHLIAYRNDFLERYGIYREIPLLELLDEEMGIGS
                     PATYTFPPSNRLIMQDKQELSSEYTDKILAVLLKTIKSNKMEIDLIQEGLVNEVLEEED
                     FNKIPDSIEIYGSIVAESASEIDRGNFKFVTGLSTISDGAGKTFGRFLNILEEEEFIKN
                     YKTIYSLEKNHSEFLYAEIVFLPSAGRLANVSLSRNFRDYEIVIGTQSSKSTKYTIPLS
                     DIVVGSTNEKFYLKSKSIGKQLKIKTNHMLNISLAPNIYRFLVEISSYGTSDCLPFLWD
                     SLNTSPFLPRITVGKSVLSLARWNVNNEVLKLPKETSFEKWKTTFYAWAAEWKMPQWVY
                     QAVSDNRILLDIYNPIHIKELYIQSRNSLGNEKITLIEQESNTLKRWEEDVEGSSYNIE
                     YVFPLIKNKKIDSLDSIISIGELLPIDTNSECIKKFPGDNWLFIKLYNDSTRDEELIYN
                     HIHEFCTNLVVNGDIDSYFFMRYADPKRHIRLRLSGDFSKGNMLYTLNQWFLSLNKIGL
                     LLIAEISTYEREVERYGGPKLIGLAESLFYYDSLCVEKILRCINNDETTLSLEEISIIS
                     IIHYLECFNIKFQKQLEIINNVTSYKNYTKEFREKRDKYLQIGNSLNNWKTLRDIENES
                     RIISILQIRKEAIQILNNSMIEVEKQAELYNTREDIILSIIHLHLNRLLGINRELETKV
                     MTLARHVLHNLRYTRERLK"
     aSDomain        complement(14692..14964)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C6351_RS24610_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="3.00E-13"
                     /identifier="RREFam001.1"
                     /label="C6351_RS24610"
                     /locus_tag="C6351_RS24610"
                     /protein_end="260"
                     /protein_start="169"
                     /score="41.2"
                     /tool="antismash"
                     /translation="NSIILAKGERINVPYSSRTEAFQGNLFNFESSSIRMTPVVQLILE
                     LAKKPIKIDEIIFALKQKYTNVLEEKIHVVLLQLIEREYLVTELSP"
     misc_feature    complement(15620..15640)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.46"
                     /tool="antismash"
     gene            complement(15907..16089)
                     /locus_tag="C6351_RS24615"
                     /old_locus_tag="C6351_24625"
     CDS             complement(15907..16089)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016113474.1"
                     /locus_tag="C6351_RS24615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24625"
                     /product="hypothetical protein"
                     /protein_id="WP_001224231.1"
                     /transl_table=11
                     /translation="MRKDDFNLDLKIQSSNKEGGPSPRTTQWTVARTIGYMTSRGVCGQ
                     NTGTVIKPNTVGCRA"
     gene            16325..16459
                     /locus_tag="C6351_RS33060"
     CDS             16325..16459
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018768041.1"
                     /locus_tag="C6351_RS33060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_255302129.1"
                     /transl_table=11
                     /translation="MLVITVHPGVPDKGVPIKKKLTVIIPLILFSGVIYLIVWRLLGI"
     gene            16811..18199
                     /locus_tag="C6351_RS24620"
                     /old_locus_tag="C6351_24630"
     CDS             16811..18199
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837770.1"
                     /locus_tag="C6351_RS24620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24630"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_106082235.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.5e-45, bitscore:
                     147.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSKSYFLFLSLISYFLFIPTPSLAEDEHNYSILLKNGTDFNNIK
                     NKLQQGGFEITYEIPEINLIQVLGTDLESKNLNHIKGIVKFSESVNTSNPKSKNVSSSF
                     SKQNEVSADLWEYQWDMQSITNNGASYNVFQGSTNVTVGIIDSGIFPYHPDLKNSLLPG
                     SKNLVPKGGLKGRESSETGDINKIDDLLGHGTSVAGQIAANGLMKGVAPGVGIKVYRVF
                     GSTSAETIWVIKAIIEAANDDVDVINLSLGDYLLKSGSYSHTGRNDSVEIEAYKQAINY
                     AYKKGSIVVAAAGNDGIDVNDQAKFHEVVNANLKTSNTTVSGIILDMPGALTNVVTVSS
                     IGPTGELSLFSNHGKDFIDIISPGGDFRLLEQYGEDMWINDHLIEQEQILTTNINGGYY
                     YDSGTSLAAAKVSGALALIVEKNKWKDQPHRAINHLYKYSTVNNPLTPRQKNLDIYKAL
                     FPHS"
     gene            complement(18577..19668)
                     /locus_tag="C6351_RS24625"
                     /old_locus_tag="C6351_24635"
     CDS             complement(18577..19668)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002169385.1"
                     /locus_tag="C6351_RS24625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24635"
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="WP_086398625.1"
                     /transl_table=11
                     /translation="MKHLRKIFKRILLLFSIFMLIGIGILFGTSYGRELRITMAGSILT
                     SQHPQYAKYTFLSQKELDKLQDRINHPKWSNSDEHIYKKIAGKRLEEFKNQPLEIDVET
                     IKSNKDSRFLFEGKLVTISNPFNVKLVSHQGTQGANRGEKISVMAKRNHALVAVNASGF
                     ADETGRGGGNVATGIVIENGKAIDTNMDSNTPTIITGLTKFGQMITGNYSTQQLLDKQV
                     VSAAGFMPQLIVNGEKMITEGDGGWGSAPRSIMAQKEDGTIMFLVIDGRQTHSIGATLK
                     ECQDILYEKGAINAMAMDGGSSATLYLGGRVINTPSTLSHEDRYLPNAWVVTANSKQKI
                     KMIIDGEKVDPKTLDKFDANFTS"
     gene            complement(19828..21156)
                     /gene="mgtE"
                     /locus_tag="C6351_RS24630"
                     /old_locus_tag="C6351_24640"
     CDS             complement(19828..21156)
                     /GO_function="GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mgtE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016110017.1"
                     /locus_tag="C6351_RS24630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24640"
                     /product="magnesium transporter"
                     /protein_id="WP_098355707.1"
                     /transl_table=11
                     /translation="MKKLLKELLVTKNNLDAEKVLRLPSYDVAQEVKRFSIEDQIILLN
                     TIPVLKSSKILQYMSAEEKYNILIHLSENKAKKLLNLQPIDELVDLLLAVHPEKQAKLM
                     AYLDKITKHNVKKLMNFKPETAGSLVTSDFVAVRGNWSVKMTLKYIREHSENVESISYS
                     YVLDSHGYLEGIVSIHELLLAADEEILSTIMIQEVISVQAEVDQQEVVKKLLNYNLAAI
                     PVTTVNNKMIGIITFDDVMNVMEAEATEDIQKLGGSEPLNQSYFEASIWSIFLKRLPWL
                     LLLFVAEAYTGTVLKYFEDEIETVVALAFFVPLLVGTGGNTGTQVVATITRAIGIGEVK
                     FKDIFRVMKKEFAIGMLLGLALGIAGLTRAYMLGVGTEVAQVVAITLLFIVIWASLVAA
                     VLPLILRKLKLDPAVVSGPFITTFVDGTGLVIYFMVAKTLLNL"
     misc_feature    complement(21254..21264)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 19.14"
                     /tool="antismash"
     regulatory      complement(21436..21601)
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as a
                     genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     regulatory      22107..22283
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as a
                     genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            22470..23597
                     /locus_tag="C6351_RS24635"
                     /old_locus_tag="C6351_24645"
     CDS             22470..23597
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722123.1"
                     /locus_tag="C6351_RS24635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24645"
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="WP_106082236.1"
                     /transl_table=11
                     /translation="MKKILKLDYLLLLPLFITCTLGIIMMYSASSIVAVQHYGYNSRHF
                     VDSQLTKLLLGTIGLIVCALLPYEIWKKRIISISIMVGGIFLLIMVLWKGKVVNNAQSW
                     IFGIQPAEFLKLGTILVTARFFALRQEQAQNNWSGIGKLLFFLATIFFLIFKQPNLGSA
                     LLILGIGFSIFLCSGININLLIKRTTIASILWLPILYYLIQYSLSEVQKTRITTIFNPF
                     VDAQGNGYQLVNSFIAIGSGGITGRGFGNSIQKTGYLPEPHTDFIMAIVSEELGFIGVF
                     IILAGVLTIVLRSLKIAQLCVDPFGSFIAIGIGCMIGMQSVVNLGGITGLFPLTGTPFP
                     FVSFGGSSLMVNLIAIGILINISIFNKINFDNHNI"
     gene            complement(23825..24862)
                     /locus_tag="C6351_RS24640"
                     /old_locus_tag="C6351_24650"
     CDS             complement(23825..24862)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016078444.1"
                     /locus_tag="C6351_RS24640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_24650"
                     /product="serine hydrolase"
                     /protein_id="WP_106082237.1"
                     /transl_table=11
                     /translation="MNHSYNEKTHTLIKQLFNKFSPKAPGFAYIASFDSGVTYKGTVGL
                     ASIEKNLPITTKNIFNIASVSKQFTAFSILLLEQEGRLSLDDSIVGFVPFIGTYAEPVT
                     LKHLIHHTGGLVDYMALAESANIKFTDSLTVEELLNHLNGHQIARFAAGTKFEYSNTGY
                     FLLSLVIEKVSGKSLRQFAKERIFDPLNMKDTTIVDCYPTTISIARGYSKNEQGAYMVY
                     ESPWEHTGDGAVHTNVEDLVRWGENLTTGTVGGKELVKRMSEIGPEISPTGETIIDNED
                     YAFGLRHAEGFNCRYLEHSGSWAGYRSYFMRFPKEYLSVVVLSNYDGFESKKYANEIAE
                     IVLEK"
ORIGIN
        1 aaactacaac agaacatgca gaattcttct gttaacagga aaatttcagc cttaaaatct
       61 ttatttaaat accttacctc cctatcagag aacgaagatg gagaatgtta tttttataga
      121 aatgtaatgg ctaaaatcga aatacataaa gataaagaaa cattaaatgc ccgtgcaaaa
      181 cgtatgagat ctaaaatatt tcataataat gatgatcaag agtttttaaa ttacgttaag
      241 tatgagcacg aaaaatcttt aacaaaacat cagttgttct atttcctaag agataaagat
      301 cgcgacgtag caatcctctc tctttttctt ggcagtggca ttcgtgtaag tgaattggcg
      361 gatcttcgta tggaagatat aaacttaaaa gaaagactca ttgatgtaat acgaaaagga
      421 aacaaagaag attctgtatg gattacccca attgcattaa atgatcttga aaaatatatg
      481 gaaattcgag ataacaaata tgctccaggg aaagaattaa aaaatgtgtt tttatcgaag
      541 tataaacata ctgcacagcc tctttcggtt agggctatcc aagatatcgt agaaaaatat
      601 actaaggcct acggtaaaag aatgtctcct cataaattaa gacatacatt ggcaaataaa
      661 ttatatatgg aagaaaaaga ctcgttacaa gtgatgcagc aacttgggca tacgagtcaa
      721 gatacagctt tgctatatac acaacttggg gaaacaacta ttaaagatag tttaggcaga
      781 ataggaaaga ataaggaata aaagttcagc aattttgtgt tgttgaactt ttattccttt
      841 acatgcttaa gatttaaacg ctatttatta ttcgttttaa atttgatttt attatgtaaa
      901 aaatacataa tttgaatcct tctataattg gtatataaag actctctctt gatggatata
      961 aatgaaaatt ttagattcct acaattgttg gttacgttaa acactgactt aatgtaaaat
     1021 taataataca ggatttactc acttttcgct ccaaccaaca aaaaagactc attctaattt
     1081 gaacaagtct ttgactcttc ccttataaaa atagcatgat tcatatcaca atacattcat
     1141 ttatatcaac acaatccatt gttaaaaacg caaaaactaa attgaaaata aagatctagt
     1201 aactaaatat aatgcccata ctttcattat tatttgaatt tctatatttc caaagaaagt
     1261 attgtcttta attcacttac aaattcccca cccggctctc cagataccca taaaccgtat
     1321 cagaatccat ctttacttac ttcattttca taattttttt ctatttcttc taattgagta
     1381 agttttgatt cagtaggttc tacttcaaaa tctttaatat taaataaccc attttcatct
     1441 ttctcaaaaa tcttaatttc aacattgctt acgttccgca aagcataata tatcctattt
     1501 gaataatttg gagcaattgt aattatacgt acttcctcat taaaacaaga ggggtaataa
     1561 gccgattgcc atgctatatt cttatcatct tcaacgactt ttaattctat aacacacaat
     1621 acgccatttt tatctttcgc taagatatca attattccgc cttcaactct atgttgattt
     1681 gcaataaact ccataccttc ctctatacat tcagtatatt cacacaaaaa taactccaat
     1741 aattcttctg taccttccat aattgcatca gtaatacata actcccatat gctttggatg
     1801 cttcttctta tactttttat cttttcatca caattgtatt gatcatttgt catacaatta
     1861 tctgaacaaa taccataaaa aatatatggt tttactgaat tagttgcatc tttaaccatg
     1921 gaccaatcca tttctgtaat agtaaataaa atttcatttt gcattctttg ctttgcatta
     1981 taaggggtac cttcccatat ataaaaacac caatactttg tttctgtaga atttgataac
     2041 ttagcaatat ctttttttct gaaacattct ttacaaaaaa actctccact ttctatcgtt
     2101 aagatattct tttttaagta tttaataata tctttatcgg ttactatacc aattaattct
     2161 ccattattaa aatcccattc ttctagacta ttactaaatg catataagta ataccgttga
     2221 tcttctaatt ctctatattc aacccttaca caaccatatc gctctaataa tctatcttta
     2281 tctattaatt tttcttttct attcaaatac aaagcatcca taactccacc tcctgctaac
     2341 agtatgaaca aaataataac attcataaaa aaacctacat tttttattat gtatcctatt
     2401 tctataaatg ataaatctct tatgtacaat tcttttggtt gaatggtttg taggtttgtt
     2461 gaaccgaagg ttttatcatt ttctcttcct tctcctacat aaacgtgcag gaattttccg
     2521 ctcaataggt catactccaa ttgaatttta actcctgctg tatgactact tccacctgaa
     2581 ccttgataat gtgaagaaaa cttatcagga agctgaaaag ttgtagaatc tagaatccga
     2641 attcgcttaa aggtcgtggt atattgatga attatttctt tttttgaatg aattctttga
     2701 gttagaaggt tagctagaat ttgttcaaga aattgtactg cggaagcatt aaatcgttgg
     2761 ttaagacctt cagaactgat aagaacacct gtagatactt caagacagct acataattgt
     2821 gtcagtgatg tacttgcaac ccgttgacta agccatacac ataaagcaac taactcctgc
     2881 gcttgatatt tactctttcg ctgaacgaat cctttttctt tggctagatg ttctagagta
     2941 agaggagaca tatgtcgttg taattcttca gcaattggtt gaagttcgtc aagaatcgaa
     3001 agattcataa agaaacgcca tcctttccta taattctaca gaaaggataa cgtctttttc
     3061 gctttatgga tagtacaaaa tcttaacttg atagtaatgg gtctgtaccc caataagaag
     3121 tgatagagat aattttataa ctcaatatgt acatgtaact ccacttcatg gacttagttt
     3181 aagatcccat gtaagtgcag gtcaacaaat tggtacagtt gatttatctg gttcttcttg
     3241 ttctcctcat gttcatatgt caaggtatac tccttctggt agtccaactt gtgattggca
     3301 agtacttaaa agatttcctt ttcatcacac tccaggtggt gtaacaggta ctccccctat
     3361 ccctgcttct gaaagttatc accctagcgt ttctccaatc catcgttcat ctgtatattg
     3421 gtaaaaaatt tgtatataat gttataatgc attttttgtc cctgcataat gtgtagggat
     3481 tttttcataa agaaaagaca ccctaaggtg ccttccttcg acttgaacca ctttaatttt
     3541 aataatatgt attggaatcc catccaatat tatattacca tgttaagtta ttttatacat
     3601 tgagaaaaaa taaaagcact ctttcgagtg ccttcaacta tactactttt aatttaatct
     3661 ctttacccat cataccacca cgagctttta aaactaagcc ttgtgcgtca gcaggaacgt
     3721 caaagatgat tttacctgtt tgagttaaac cagggttaag ttgttttaag aagaaatcag
     3781 atttaccgcc gttacctaca tcgaaagctg tttgagcttg tgcagagtac ttgaattcac
     3841 gatcttgatt atcaactaat ttgaagctat tagcatcaac agtgatagca tctttttggt
     3901 tgttagtgat agaaatttca actactttaa acacaccttg cgctttttcg tttaagtatt
     3961 ggccacctac tgaatctgtt gattcaacag aacctacagc gattttaact ttagaagact
     4021 cgccttcttt agaaagctcc tttttaggct cttctttttt aggttcttct ttctttggct
     4081 cttccttctt tttaggttct tcctttttca cttcttcttt tttaggctct tcttttacct
     4141 ctgtagaagc ttgttgagtt gtttctttag ctttaggttt ctcttcttta tcttttgttg
     4201 gtattaatat catagctaac acaaggcata caatcgaact aataaaaagt ttcgccttag
     4261 gttttctttt gaacagagca atgataaata atacaaacag cactattgaa gctagaaaaa
     4321 ttaataccgc tagcgtttcc atttgcaatc cgcctttttg atattttttg aacgaaatgt
     4381 aagatttccg agattatcat agcaaacaat ttatctgtat attgttatat ttcgtcgaac
     4441 gaaaataaaa aaagagagac tccgctcatg tgaagatcat ttatctagta ttgagcattt
     4501 aataattatg ataagtacaa gtattgtaag gaggtgtgta catgaatgaa aaaaatgagt
     4561 ttttgagtgg tgcagcattt gatcctaatt tgttgggtcc tacattgcca cctattccag
     4621 tgttcacttt acccacagga cctactggtc cgactgggat tacaggtgta accggaccga
     4681 caggagcaac agggattact ggcccaacag gtcctactgg agcaacggga cctacaggca
     4741 ttggagcaac aggtcctcaa ggattacctg gtccaacggg tccaactggt actaccggat
     4801 caaatgcacc atcaattaat ttccgcgcag agaaagcacc tgtccaagat tattcttcct
     4861 cagattttct tcaagtatca tttgaaagca tagtatttaa taatggaggt ggttattctt
     4921 caattactaa cacgtttact gctcctatag atgggattta tttgtttacg gttaacttgg
     4981 ctttttctac tacttctctg ccagctgaag tatctcttga gataagaaaa aataatctac
     5041 ctataagtgt tgatacagaa acttttaata tcacaagcct accttttata aacaatacaa
     5101 ctattattaa tttagtagca ggtcagaata tagctgtgtt tttttcctcg tcacaaagtg
     5161 gagctcttac tgaaactcct gttgcgtatt ttagtggaac aattttacct taattgatac
     5221 aaaacaagag agccgtttgg ctctcttgtc atatttggtg aaattatgta aaatttcacc
     5281 tctttccttt ggaaaagatt tcttttatga tgaaatcaaa tcacagtata tccttttttt
     5341 ttgcaacatt ttcacgtaca atgaaacttg ttttgcaaaa cgtccttgct gacgtccatc
     5401 tagctcctca taagctcgtt ggatgtcatt aaatagtaat cccaatagcg catcttcttt
     5461 cctgttctcg aagttaagaa gagcatctgt ggaggtatta aaaaacgacg caagtacctt
     5521 taaactttcg agatcaggtt catgacgatc agtttcccaa tttttgattt gtccgcgtga
     5581 taaacccgtt ctttcagaca attgttcttg cgttaaatca aaagactttc ttaactgttt
     5641 aatgttttgt ccgactgtat tttccatagt ttgagtataa taatcgcctt atcactatac
     5701 cataattggt cgatactctg acttttttaa actattttgg tacttttgta acctttataa
     5761 atatgtatag aacaaatgtt tgtttagggg tatcgccaca tcgctatcaa gctaagctta
     5821 tacaacgtca attatagtag aggttatttc ttttttttat agagcaagtg taggtgattg
     5881 aaagatttgc atacgaaata aaccctaacg ggtttcattt tttgaattaa gctgcttgat
     5941 tatcagacat ggtaaaattg taaacgacac ctaatatatc aaagactgtt ttcttctcat
     6001 atcgatgaga ttttctcccg ttttgctgta ggaggttgaa caggcgaagt aacatctttg
     6061 atagctcttg ggtgtctttt tgtatcgatt ggaaaagaag aaaaaagtaa tctttaatca
     6121 tatatatgac cttatattca ctcagttctc gtttcttttt cataagaagt aattgccgca
     6181 tttgaaacat tgtagaagaa caaagtagaa tggcaatcag ttgcccatac aaatggcatt
     6241 ccaatcgttc tcgttttatc tttttacaat gatgaatatg aaagaatgat ttccatgttt
     6301 taaataaaat ctcgatttgc gaacgtaaag aataccaatc atgtacttgt cccatcggga
     6361 caatatctat aggggtattt gtcatatata cattgatacc gctaagtcgt ttactacgag
     6421 cagaatactt cattcctttc tttttttctc ttaccgtttg atcgtgtaat cgtttttgtt
     6481 gttgttcttt tgttagtcga tgaacaatca cacgagttgg tactttatca gtcattccta
     6541 cataagcgtc ggatatttca tatgtttgtc ctggctgaag agagttcatt aaaacctcca
     6601 tatctatttg gatatactct gtactcttct taattctgcc atcttgaaaa taatcagggt
     6661 ttggattttt ttgataaata cgtgtatttg atttgatacg tgagatataa taagcctttt
     6721 tatcttgtat atgttgaaga tctttcaaat gaaaataacc taaatctcgg atacataaat
     6781 cattcgctgt tacagttggg gcacacagag aaccgtaggt tctatcatgt tgtttacctg
     6841 gacctgtatg aatatgaaga aattgtccac ttaataaatc atactcaagt tgtatcttta
     6901 ctcccgctgt atggctgcat cctcccgcac caggataaat tgatgaaaat atatccggga
     6961 gttgaaatgc agttgaatct aagatgcgaa tactcttaaa aatagaagta tagggagaag
     7021 aaaacaacct agatgaagat aattttcgat tcagaagttt agccaatact tgttgtagaa
     7081 actgcgcggc tgcggcgtta aatctttgat ttagtccttc aggacttata agcacttctg
     7141 ttgatgcttc taaacaacta cataactagg ttaaggaagt ttttgctaca ctttggctta
     7201 cccatacgca taaagctact aaatcttgtg cttgatactt acttgttcgc tgtacaaacc
     7261 caacatctct agctagattc tgtaaggtat ttggggataa tagactctga atctcctgtg
     7321 aaaatagttg tagttcgtta gctacagaaa tagacataca aaaaacgcca tcctttccta
     7381 taattctata gaaagaataa cgtatttttt tcattttgag gatatttctt tttattagtt
     7441 tgatagcgat ggggttcgtc cccacaaagt aagccgcatt ctagccaaaa cgcaatcttt
     7501 agatcgaaaa ataagaataa aaccaatgaa taaatattta atttatatta ttttaatctc
     7561 attttcgtaa tcttcaagtt ccttatctgt cattacatat ggagagggat cctcttttat
     7621 aaaccgtacc gcatttagtc cgatcatctg agcagcagcg gacggctgac catctggaat
     7681 aataggcgaa atggacaaat cggcaacctt aagatttttg gtaccaaaca cattgaggaa
     7741 tccatcgaca accccttctt gaatcgtctg tcccatccga cactgaccgc ctaaagagaa
     7801 gttcgtgtaa gaggctttga cataattctc aagctgctgt tgtttgttgg gatcattgtt
     7861 aggtagctcg aatatacttt ccggaggata tacaactttc ccgattccgt tatttgggta
     7921 tttcagtgga tctctagcct ctacaataat attataaatt ctcttatatt gatcgaccat
     7981 atatgttagg tcattgggat cttccaacgg attgaagtta agagatggat aagcctctgg
     8041 gtcgctatgt tccactagca ctgtacccct gctttttgta ttcacgtcta caataccaaa
     8101 actcatgata cttggagtag tttggaaagt taaatctaaa ctccaaccat tgctgatcac
     8161 atctggagca gggataaaaa atgggatagg agcccctatc agttggagac gacgactttc
     8221 tagtagattc attggattct ctgcttggaa agcacctaag ataagtggaa agttgggatc
     8281 agcaaaaaat atcggaagaa tttgagaggt atctatttca actcctaatc caacataacc
     8341 atgagtttga agattgtggc ccacatttgg actctctata aatgttggta tacctgcttt
     8401 agccaaatca tccgatttcc cgattcctga acgttgtaga atgactgagg aaaaaaatcc
     8461 tgcagagacg ataatacctt ttcttgcaaa ccttctatgt gaaacaccat ccttgacaaa
     8521 ttcaacacca accgcaatgt tcagtccatt ttttttctta aataaaattt tgttaacggt
     8581 tgttttagct aaaataacta actttcttcc accaactcca aattcatctg gatggaactg
     8641 gtttccttga ctgacaatat ggtcatttaa ataacctgtt gccgttgagg atcggacaaa
     8701 ttgaccgggg ctaatttctt tttgaataat ttgcgattta taaaatgtac aatcccttat
     8761 gccggtatta tagtccacag caatcggcgt tcccaataca gtgtttgttg cttgaactaa
     8821 cgtattgatc aatccactag ggggaatact ctgttgccta ataaagattg gtccttgtga
     8881 tcctcgttca tcagggtctt gtgtcgatcc tgtataggtt tcatttttta caaataagga
     8941 gctaatcttg tcgtaactcc attgattacc aacaagactt gcccactggt tatacaactc
     9001 tttactccca cgtacggcgt acatgtcact aatttctgaa cttcccccta tggcgcgacc
     9061 atttgttgca ataagtgtac gtgcaatagt cgattctaat tcagaagtaa cattaaagct
     9121 aaacctgtta cctcgagttg tattaatggc cgcaagaacg ctagggttac ttagctcatt
     9181 cgtcatattt gttcctgctt ctagcactag tacagaagta cttttgtcat ccgttaattc
     9241 tttggcgatt acccctccag cagttccggc accaatcacg atataatcaa atttagtagg
     9301 gtctattggt tttataggct ctggaactgc acaaggaaat gcacaaggaa ataatgaata
     9361 aggaaattcg caaggattaa aataatttct attttttgat ggcataaata atcaagctcc
     9421 ttttttgcat ttagtatatt aaatgtaaga aagaatctgt ctcttgtacc agtgtcttta
     9481 tttattaaaa aaatgtatgt tctatacatg taaagttaat ataacgcatc attatcaata
     9541 gacaataacg gatagaattt tcgttttggg gaattttgat tttttagctt gatgggcatg
     9601 gggtaccgcc ccacatccat caacttaaga aattggtagc tccccaaaac gaagaaaatg
     9661 cgttgaattc taataaataa ctgtaaaata ataaaatttt cgttttgggg gcactttaaa
     9721 atcttagctt gatgggcatg gggcggtacc ccttataatc atgattaaat taaccaattc
     9781 gtattttata acaactgtta aacaattttc atgtattcat tttgtattca ttttgtatga
     9841 atttagatat gaaaattgtt ttattttgca cacctatgaa tgtgattttt gtactaattt
     9901 ttatagcttt atacagattt accacgtgct tatctataat tttattagaa tgactacact
     9961 atccttattt aattccgagt atattttagt atcccgtaat ttaattatat aaataaccct
    10021 gtttaaaata tctactttta tttcttgaac aagcctctac attcatcata ataccagcta
    10081 aaccatggaa caaagatgaa ggtaagtcag cttgaacacg ttttaaatat tcaagtgcaa
    10141 gtatatccca ctccccatca ggatctatat tatctaacac cccaagtagc aaacatattc
    10201 ctggataacc agaaataaga gaattacttt tcaattcttt tagttcccta tcttcatcgg
    10261 ccataataat actatcaatt tttgatacac tcttgaaaat tttagcagtt gaaaaaataa
    10321 catcctgtac tttttctttc aatctttgat tttgaatcaa aaaaaattct tgtccttgaa
    10381 ccatttttca cctctagaaa tttttttata aaacaaaata aacataatat tttatagaaa
    10441 taaattaatg aacttgcatt ttcgaaccct tagaatatac ttctgcttgc atataatata
    10501 atttagcgta aacacccttt tcatccatta acttttcatg atttccacac tctttaattt
    10561 caccattttc catcaaaata attttatttg caaattgcac agaagaattt ctatgtgaaa
    10621 taaatattcc aatacggttt tgaacaagct ctttaaagcg attgaataca tccttttccg
    10681 cctcaggatc taaagctgag ctaggctcat ctaaaatata catactagca tttttaatta
    10741 tggcccttga aatagctatt ttttgccact ggccaccaga taattgatac ccttctgaaa
    10801 accattttcc taattgagta tctaatttat taggaagaga ttttatgact tcatgtatgc
    10861 cagattgcaa agcagcatta tttattttct catcatcgtt aatataacct atatttccat
    10921 aagaaatatt atttcttaca ggcagttcgt atttcacgaa atcttgaaat acaactccaa
    10981 tttgttctct tacactttct atagaatacg agttcaaagg ttgagaattg attaagattt
    11041 ctccttcata accatggtat agacgagtca aaactttaac taacgtagat tttccagatc
    11101 catttttacc aattatcgct acgatatctc cttttctaaa agtgaaagaa atatttttta
    11161 aagcataagt ttcattattg ggatatttaa aggatacatt tttaaattct atggattcta
    11221 tctcgctcaa ttcattgact gaacatttag aattatcatt ttcttcaaca tccaaatagg
    11281 aaaataactg ctcaatgtac aaattgcttt catacaatga aaatatttga tgtaacagtg
    11341 attgagatgc tttttgagtt gcaaataagg cttgtatgta actaaccatt gttcctatca
    11401 aaatttcttt tataaaagta gataataaaa tgataaatat taaaattcct actacaatta
    11461 aattgataaa gtcataaata aatgttattt ttaatcgtct tttttctatt gatttatcaa
    11521 cttgaaagaa atccttataa attccagaat actccttaat gatatgagca cctaaattat
    11581 tcaattttat ttctttaaaa gtagcatctt tcgttagcaa ataacttaag taccataatt
    11641 tcctattaag gggtgctcgt tcccattcta tgtcaaactc ctttctccct aatttcaaaa
    11701 atgatataga tgaaaaaaag ggaacaataa gtaggattat gaccacccac cacttccacg
    11761 caattaatat agtagctgtg gaaattaaag taacaaaact attaataatt gataaaattt
    11821 gattgaagat ttggtatggt ctatagtcta cttctctttg agctctctgt aactggtcat
    11881 aaataacatc attttcaaaa tccgctaatg ttaacatcga agatttttcc attaagatca
    11941 cattaactga ataggacaat ttcactttat atattgcctc atagtaattt aaaaattgtc
    12001 ctattaataa ttgcaataaa tatatactaa ttaaaataac caaagaattt agaacaatat
    12061 ttaatccttg ttcccatcca attacaatac tgtttattaa gaattggttt cctaataaaa
    12121 gcagagcagg aaaaattcct gccattatat ttaaaagcat gataaaaata attagttttt
    12181 tatcaacctt ccataataac ttaaagattt tcggccaata tttaaaagaa cctaatattt
    12241 ctcttaaact tagattcgta ttccaattca cttcaatctc tcccttgtat atctgagatt
    12301 atgaagcaca tgtctagcca atgtcattac cttagtttca agttctctat taattcctag
    12361 taaacgatta aggtgaagat gaattatact tagtattata tcttctcttg tattatataa
    12421 ctctgcctgt ttttcaacct ctatcatact attgtttaag atttgaatag cttcttttct
    12481 gatttgtaaa attgagataa ttctagattc attttcaata tcccttaacg tcttccaatt
    12541 atttaaagag tttcctattt ggagatactt gtcccgtttt tccctaaatt cttttgtata
    12601 atttttataa gaagtaacat tattaattat ttctaactgt ttttgaaatt ttatattaaa
    12661 acattcaagg taatgaatta tacttattat tgaaatttct tcaagtgata aagtagtttc
    12721 atcattatta atgcatcgta aaattttctc tacacaaagg ctatcgtaat aaaagagtga
    12781 ttctgctaaa cctatgagtt tcggtccccc atatctctcc acttctcgtt catatgtaga
    12841 tatttcagct atcaacaata atccaatttt atttaaagat aaaaaccatt gatttaaggt
    12901 atatagcata ttccctttac tgaaatcacc agataaacgc aatcgaatat gccttttagg
    12961 atctgcatag cgcataaaaa agtagctatc tatatcacca ttgactacca aatttgtaca
    13021 gaattcatga atgtgattat aaattaactc ttcatctctc gtagaatcat tatataattt
    13081 aatgaacaac cagttgtcac caggaaattt tttgatacat tcgctattgg tatcaattgg
    13141 taataattcc ccaatcgata taattgaatc caaactatct atctttttat ttttaattaa
    13201 tgggaaaacg tattctatat tataagagga accttcaaca tcttcctccc accgttttaa
    13261 tgtgtttgat tcttgttcta ttagggtgat tttttcattt cctagtgaat ttctcgactg
    13321 aatatatagt tcttttatat ggattggatt atatatatca agtaaaattc ggttatcaga
    13381 aacagcttga tatacccatt gtggcatctt ccattctgct gcccaagcat aaaaagttgt
    13441 tttccatttc tcaaaagaag tctcctttgg taacttaagt acttcattat ttacattcca
    13501 tcttgctaaa gataagacag acttccctac tgttatacgt ggtaagaaag gagatgtatt
    13561 taacgaatcc caaaggaacg gcaagcaatc agaagtgcca taactagata tctcaaccaa
    13621 aaatcgatat atattgggtg ccaacgaaat atttaacata tggtttgttt ttattttaag
    13681 ttgcttgcct atagatttag attttaaata aaatttctca tttgtagaac caactactat
    13741 atctgacaaa ggtattgtgt attttgtact tttagaagat tgtgttccta tcacaatttc
    13801 ataatcccgg aaattcctag acagagatac attagctaat cttcctgcag atggtaaaaa
    13861 aacaatctcc gcataaagaa attcagaatg gtttttttct aaactataaa tagttttata
    13921 atttttgata aactcctctt cttctaatat atttaaaaac cttccaaatg tttttcctgc
    13981 gccatctgat atagtactta accctgttac aaatttaaaa ttccctctat ctatttcact
    14041 tgcactttca gcaacaatac ttccataaat ttcaatagaa tcaggtattt tattgaaatc
    14101 ctcttcttct aatacctcat tcactaatcc ttcttggatt aaatcaattt ccattttgtt
    14161 ggattttata gtttttaata atacggccag tattttatct gtatattctg atgacaattc
    14221 ttgtttatcc tgcattatta atctattact tggtgggaat gtatatgtag ccggcgagcc
    14281 aattcccatt tcttcatcta agagttctaa cagtggaatc tcacgataaa ttccgtatct
    14341 ttccaaaaaa tcatttctgt atgctattaa atgttgcttt tgagaatatt gcaaggaaag
    14401 tttccataat acagatgcaa cattcgctac ttcttcacca actgatttac tcaaacagat
    14461 atctttatcc tctaatctta catctatctg tatattatct ttagtagcta ttattttctt
    14521 catttgctga tttatttcct taacaacatg tagaccttca cctatatatt tttgatcgta
    14581 atatgtaatc aattgattta attgtttcaa atctattttt aattcttcta tcccctgaac
    14641 atgttctaac ttctctatta aaaattcaaa aggtgattct atcattaaag atgggcttaa
    14701 ttctgtaact aaatactctc tttctattag ttgtaataat actacatgaa tcttttcttc
    14761 taacacatta gtatattttt gttttaaagc aaaaataatt tcatctattt taataggttt
    14821 tttagccagc tctaaaataa gttgaactac aggggtcatc cgaatagacg atgattcaaa
    14881 attaaataga ttcccctgaa atgcttcagt tcttgaacta taaggtacat ttattctttc
    14941 accctttgct aaaataattg aattaacctg cactttaagt tgcttcatta caaatatatt
    15001 actttcaagt ttatgtatta aagctaaaag ccatgacata tcaggacggg tttgtttttt
    15061 gtggaataaa ggcttttcta tggaaaaaga ggtgaaagaa tcaaaagtac catatgtaac
    15121 accagcaaat aatccaaatg gtgtaggcct tgtagacatt cgaattaaat acttgtttac
    15181 cgcgtgaatg atttgttccc ttcttttttt gttactaatg tgatttaggt caataattga
    15241 gttatatagt gaactactag aaacaaaaat cgcctcttga ataataggat ctgaaatttt
    15301 agtttctaat ttcttcatca tttgttccaa ttcaactttc tcgccatttg tattttcgaa
    15361 taaatcttta taaaaattta aggataacat aggtgatcga accatgaaaa aatttaatgg
    15421 ttcaaacaaa tttgtacttt taattatgga attcttcttt tcttttttca tttaaaatcg
    15481 tacctttcca tattaattac catactattt agaaatatat tagagtacag attgttaaaa
    15541 atataattgt tccttaacta caatcatata tcataggatt tttaggttgg atattagtta
    15601 agtagttttt actaggagat aataggctct atgaggaaaa gtatatacat ttactaaaaa
    15661 tctaatagca attaatttag taaaatataa tatattttac atatatttaa tgtaatcatt
    15721 aaatatttat tatgctccat aaaaattaat tatttattag caatttcatt cgatgaaata
    15781 ctcgggatat ttaaattata ttttgttact aatgtgattt ataaataatt taaaaaccta
    15841 ttatatttat ttatagaaga agtattcaaa aaaatactcc ttctatataa tttttatttt
    15901 tctaagttac gctctacaac caactgtatt gggttttata accgtacctg tattttgccc
    15961 acaaactcca cgacttgtca tatacccaat tgttcttgca actgtccatt gagtagttcg
    16021 tggtgatgga ccaccttctt tattagaaga ttgaattttt aaatctaaat taaaatcatc
    16081 tttacgcata ataagcctcc taaatttttt taatattcac gtgaacaatt agataatacc
    16141 atacgaaaat ataaaatcaa ccattttatc ccaattttaa gaaaagtatg tattttataa
    16201 atattatata ttttatttat tttttgtttg aaatggaaat atttatgata caatcttatc
    16261 aaagataggc gacaggagga ggattatcat taaaatattt ttagctacta ttggtgctat
    16321 tcttttgctc gttattaccg ttcatccagg tgtaccagat aaaggtgtac ccatcaaaaa
    16381 gaaattaaca gtaatcattc cattaatttt attttctggg gtaatttact taattgtatg
    16441 gcgattatta gggatctagt atttcaagct aaatccttac ttcatcacag tctttttcta
    16501 tttcttcaag aaacaagatt cccagttaca gaaatccaca tttgatatca attttactat
    16561 ttaaatattt tacactttta tccaaattat attgcaataa gaagaaaaag aacactcggt
    16621 ccccacaaaa ggtttctttt atggggattt taaatctatg ttaatgtaat ctcagaatag
    16681 ataaatgtta aatttctact taatatgaat attacgtaat aacaagacac taaattcaat
    16741 ccaattaaat tatattattt tcttaatata ttggttgaat attattattc aaaataatgg
    16801 aggttataca atgaaaagta aatcttattt tttatttctt tctttaatat cctatttttt
    16861 atttatacca accccatcct tagctgaaga cgaacataat tactccatat tattaaaaaa
    16921 tggcactgat tttaataata ttaagaataa gttacaacaa ggaggttttg aaattacata
    16981 tgaaatccct gaaattaatc ttatacaggt cctaggaacc gatttggaaa gtaaaaatct
    17041 taaccacata aagggaattg ttaaatttag tgaatcagta aacactagta accctaaaag
    17101 caaaaatgtt tcatcttctt tttctaaaca aaatgaagtt tctgcagact tatgggaata
    17161 tcaatgggac atgcaatcca taacaaacaa tggagctagt tataacgttt ttcagggatc
    17221 tactaatgta accgttggaa taattgattc tggtattttt ccataccatc ctgatttaaa
    17281 aaatagttta cttccaggtt ctaagaattt agtaccaaaa ggtgggttaa aaggtagaga
    17341 atccagtgag acaggagata ttaataaaat tgatgatcta ttaggacacg gtacaagtgt
    17401 tgctggacaa attgccgcaa atggtttaat gaaaggtgtt gcacctggcg ttggcataaa
    17461 agtttatagg gtttttggaa gtacatcagc agaaacaata tgggttatta aagctattat
    17521 agaggctgcg aacgatgatg ttgatgttat taatttaagt cttggagatt atctattaaa
    17581 aagtggttct tacagccaca cggggagaaa tgattcagta gaaattgaag catataaaca
    17641 agcaattaat tatgcgtata aaaaagggag tatcgtagtt gcggctgctg gtaatgatgg
    17701 aatagatgta aatgatcaag ctaaatttca tgaagtagtt aacgctaact tgaaaacctc
    17761 caatacgact gtatctggaa taattttaga catgcctggc gctttaacaa acgtagttac
    17821 agttagttct attggaccta caggagagtt gtctttattt tcaaatcatg gtaaagattt
    17881 cattgatatc atatctccag gtggagactt tagattatta gaacaatatg gtgaagatat
    17941 gtggataaac gaccatttaa ttgaacaaga acaaatacta acaacgaata ttaatggagg
    18001 atactattat gattctggaa catcactcgc agcagccaaa gtttcaggag ctctagcttt
    18061 aattgttgaa aaaaataaat ggaaagatca acctcataga gcaataaatc atttatacaa
    18121 atatagcacc gttaataatc cgttaacacc tagacaaaaa aacttagata tatataaagc
    18181 tttgtttcct catagctaat tgatttccgt tcaaaatgtt tatttattat aaaataatac
    18241 tcaattgaat gtttttccct ttttagccta gaatgtatta aaacttcatt aatatgagtc
    18301 tatagtgcta tgttaaataa ggtgtattta tacctaacac tatagacttt aaataagatt
    18361 tttacaatat gatatataat tcttaaactt ctcatcatct gattgctcat ctttaaatac
    18421 aaaattcaaa tttggttcag gtcctgatac aaatacatga ggaatacttt taaaattatt
    18481 gaataataat tcctactcgt gccagcacgg ttacgtattt ttttactttc tttatgaaca
    18541 acctccactt tttctgcttt tcattatttt tacttattat gaagtaaagt tcgcatcaaa
    18601 tttatctaat gttttaggat ctactttttc tccatcgatt atcatcttta ttttttgctt
    18661 tgaatttgct gttaccaccc aagcattcgg tagatagcga tcttcatgag ataatgtaga
    18721 aggtgtattt ataactcttc ctcctaaata tagagtagcc gaagatcctc catccattgc
    18781 cattgcattt atagctcctt tttcatatag gatgtcttga cactctttta acgtagctcc
    18841 tatactatgc gtctgtctac cgtcaataac tagaaacata attgtaccat cttctttttg
    18901 ggccataata cttcgcggag cagaacccca accaccgtct ccttctgtaa tcattttttc
    18961 tccattaaca attaactgtg gcataaatcc agctgcggaa acaacttgtt tatccaaaag
    19021 ttgttgggta gaataatttc ctgtaatcat ttgtccaaac tttgttaacc ccgtaataat
    19081 tgtaggggta ttactatcca tattcgtatc aatagctttc ccattttcta ttactattcc
    19141 agttgcaaca tttcctccac cccttcctgt ttcatcagca aatccacttg cattcacagc
    19201 aacaagtgca tgattacgtt ttgccattac actaattttt tctcccctgt tagcaccctg
    19261 tgttccttga tggctaacaa gtttaacatt gaaaggattg ctaatagtaa ctaattttcc
    19321 ttcaaaaaga aaacgactat ctttgttact tttaatcgtt tctacatcaa tttctaatgg
    19381 ctgattttta aattcttcta atctttttcc tgctattttt ttataaatat gctcatcact
    19441 gtttgaccat ttcggatgat taattctatc ttgtaattta tctagttcct tttgggatag
    19501 gaatgtatat ttcgcatatt gcggatgctg agaagttagt atactcccag ccattgttat
    19561 gcgaagctct cggccatagc tagtaccaaa taatattcct atgccaataa gcatgaaaat
    19621 agaaaataga agcaaaattc gtttgaagat ttttcttaga tgtttcatag ttttatcctc
    19681 cggtattaat tacattcaat gaatctttta aaatattttt taataaagac aaaagtattt
    19741 attttcctca ttcccgagtt ccccactaag tcttagcaag caatgcaaaa tacttatttt
    19801 acatttcgta tttatttgag tgtatactta caaatttaat aacgtttttg caaccatgaa
    19861 ataaattact aaacctgttc cgtcaacaaa tgttgtaata aatgggcctg aaacaactgc
    19921 aggatctagt tttaattttc ttagaatcaa aggtaaaaca gctgctacaa gagaggccca
    19981 aataacaata aataataaag taattgctac aacttgtgca acttctgttc caactcctaa
    20041 catataagca cgagtgagcc cagctatccc aagtgcaagt ccaagaagca tacctattgc
    20101 aaattccttt ttcattacac ggaaaatgtc tttaaatttc acctctccaa taccaattgc
    20161 acgagtaatt gttgctacaa cctgtgttcc tgtattccct ccagtaccta ctaataacgg
    20221 aacaaagaaa gcaagggcaa ctacagtttc aatttcatct tcaaaatact ttaatactgt
    20281 acctgtatat gcctcagcaa caaaaagaag taataaccat ggtaggcgtt ttaagaaaat
    20341 gctccaaatg ctagcttcaa agtaagattg attcaatggc tcacttccgc ctaacttttg
    20401 aatatcttct gtagcttctg cttccataac attcattacg tcatcaaaag tgataatacc
    20461 aatcatttta ttatttactg ttgtcacagg tattgctgct aaattataat tcagtagctt
    20521 ttttacaact tcttgctggt caacttcagc ttgtactgaa attacctctt gaatcataat
    20581 agtagataat atctcttcat ctgctgctag taataactca tgtatggaaa cgattccctc
    20641 aagataacca tgactatcaa gaacataact ataagatatt gattctacat tttcagaatg
    20701 ttccctaatg tacttcaatg tcatttttac tgaccaattt cctctaactg caacaaaatc
    20761 acttgtgaca agacttcctg ccgtttcagg tttgaaattc atcaattttt ttacgttatg
    20821 ttttgtaatt ttgtctagat acgccattaa tttagcttgt ttttcaggat gaaccgctag
    20881 aagtaaatct actaattcat caatcggttg taaatttagt aactttttag ctttgttttc
    20941 agataagtga attaagatat tatatttttc ttctgcactc atatattgaa gaattttaga
    21001 gctttttaat acgggaatcg tatttagcaa tatgatttga tcttcaattg aaaatctttt
    21061 tacttcttgc gcaacatcat acgacggaag acgtaaaact ttctctgcat ccaaattatt
    21121 tttggttaca agtaattctt ttaataattt cttcatgtta actcctcctc atattgctaa
    21181 gggagactct agagtttcat gagtggtttt gttttatttt atctgtctaa aattttttat
    21241 tagagcaata atagttacat tgcaaccaat tcattattta gaattacctc ctttttgaat
    21301 atagacaaga taaaacaaat aacattaaac agaaaaacct ttactcaaaa aggagtaaag
    21361 gttttttaca atacaaataa atgattatta agacagctct gccaaaatca cagaggtgcc
    21421 tttctatcaa atcgtatacc actccctcgt tgagttttag cactgtatag cataggtttt
    21481 tataaccagc tacattaaga agggccttaa tccgaccgtt cctgttgacc cattggcgtc
    21541 tctcgacatt tttgggcagc agcgtttctc tatacaggag cctcacctaa caaagtttat
    21601 tgaattactt caaaatttaa accagaattt aatatttgtc aactgacttt caattccatt
    21661 cataaaaaaa tcttttatgg aaaatgaaat tatattttat tataaattta aaattcccct
    21721 aaaaaacata gaattcaaat agatttaatt cgaagaaacg ttataaaaca tatgaaactt
    21781 attgttttta aacaaattcc aactttataa cagaagatga ataattagtc attctgtata
    21841 tcaaaagaac attcataaaa aaatcttctt ttatgattac aatcttcttt actgtttatc
    21901 aaatttatat ggttaaacta cttaatcaaa ctatacacta caagttgaaa atatatactt
    21961 atacagaatg attacataca ttttctcata tcatttctca aaggactata aagctataat
    22021 catataaaat tagcaatacg gttacttgac aagaaaaaaa tatatattta tgcttgctac
    22081 acgaaacaaa cacataaaat ttatattgct taacctgtta ggtgaggctc ctatgcaaac
    22141 acaggctatt gcccaaaaat gtcgaaagac gccaatgggt agaacaggaa ttgtcggatt
    22201 aaggctcttc ttaagatagc taagtaatga attttcatta ctttacgttg tatagtgcca
    22261 aagctctact agggggagaa aagccttatt tagtcatgcc attttgaatc cctctagtta
    22321 tatactaggg ggatttttgc gtaaaaaaac agggagtaag cgatagaatc ttcctaaata
    22381 aaagtcatat ttagtaatag acgagaacaa gattctattc attagcaaat gtaatataat
    22441 gttttgtttt aaatcaggag gatattaaaa tgaaaaaaat attaaaactc gattatctat
    22501 tgctccttcc tctattcata acatgtactt taggtattat catgatgtat agtgcaagct
    22561 ccattgtcgc tgtccaacat tacggttata acagtagaca ttttgttgat tctcaattaa
    22621 caaagctact tttaggaaca atagggttaa tagtttgtgc tttactccca tatgaaatat
    22681 ggaaaaaacg aataatctca atctctatta tggttggggg gattttttta ttaattatgg
    22741 ttttatggaa aggaaaagtg gtaaataatg ctcaatcatg gatctttgga atacagccag
    22801 ctgaatttct taaattagga acaatacttg taacagcccg tttttttgca ttacgacaag
    22861 aacaagctca aaataactgg agtggtatcg gaaaactttt atttttttta gctacaattt
    22921 tttttcttat ctttaaacaa ccaaatttag gatctgcact tttaatatta ggtataggtt
    22981 ttagcatatt tctttgctca ggaataaata taaatctact aatcaaaaga actaccatcg
    23041 cttctatttt atggttacct attttatatt atttgattca atatagttta tcagaagttc
    23101 aaaagacacg tattactacg attttcaatc ccttcgttga tgcgcaagga aatggatacc
    23161 agcttgtaaa ttcttttatt gccattggct ctggaggaat cactggtcgt gggtttggaa
    23221 atagtataca aaaaacaggt tatctgccgg aaccacacac tgattttata atggcgatag
    23281 tttctgaaga actaggattt attggtgtat ttattatatt ggctggagtt ttgactatag
    23341 tacttcgctc cttaaaaatt gcacaattat gtgtagatcc attcggcagt tttatagcaa
    23401 ttggtatagg atgtatgatc ggtatgcaat ctgttgtaaa tttaggtggt attacaggac
    23461 tatttcccct tacaggtacc ccatttccat ttgtaagttt tggtggaagt tctttaatgg
    23521 tcaatttaat agcaatagga atattaatta acatttcaat ttttaataaa attaattttg
    23581 ataatcataa tatataattt ttatatttta atttaaaaaa ttttaaaatt cgacctcatt
    23641 aattaaacta tatttaaaga atttctaatt attttttaac tgtataaata ttaatattta
    23701 tgttcgtttt aatacgaaaa aaggcaggca taaatatatg cttgccttcc gttctcaaaa
    23761 tcaattaaac ctaaaacaac gtgaggttaa ccaaatttag atactgtctt ctacgcccta
    23821 ttttttactt ttctaaaaca atttctgcta tttcattagc atatttttta gattcaaatc
    23881 catcatagtt acttagtact acaacagaca aatattcttt tggaaaccgc atgaagtatg
    23941 aacgataacc tgcccagcta cctgaatgtt ccaagtatcg acagttaaaa ccttctgcat
    24001 gccttagccc aaaagcataa tcttcattgt caataatcgt ctccccagtt ggagaaattt
    24061 ccggacctat ttcgctcatt cttttaacaa gttcttttcc gccaacggta cctgtagtta
    24121 aattttctcc ccatcttaca agatcttcaa catttgtatg aactgctcca tcccctgtat
    24181 gttcccaagg gctttcatag accatatatg ctccttgttc attctttgaa taccctctag
    24241 caattgatat agtagttggg tagcaatcca caattgttgt gtctttcata tttaaaggat
    24301 caaaaatacg ttcttttgca aactgacgta aagacttccc acttaccttc tctatcacta
    24361 gtgacaataa aaaatatcct gtattgctat actcaaattt tgtaccagct gcgaaccttg
    24421 caatttgatg accattaagg tggtttagca attcttccac agttaatgaa tcagtaaatt
    24481 taatatttgc tgattcagct aatgccatat aatcaactag tccaccagta tgatgaatta
    24541 gatgtttcaa tgttacaggt tcagcatatg ttcctataaa agggacgaac cctacaattg
    24601 aatcatctaa acttaatctt ccctcttgtt ctaagagtaa tatagaaaat gctgtgaatt
    24661 gtttagaaac tgaggcaata ttaaaaatat tttttgtggt tataggtaaa tttttctcta
    24721 tagaagctaa gccaaccgta cctttataag ttaccccgct atcaaaacta gcaatatatg
    24781 caaagccagg agcttttggt gaaaacttgt taaataattg tttaatcaat gtatgtgtct
    24841 tttcattata tgaatgattc atctcaatct catacccctt tcattaaata attcaaaata
    24901 gattacccta ttatctttct catattgaat ttaattaacc ttcatatcga atgtttgata
    24961 taggggaaat ctcaagttat ctcattttag tttcccggga aactaaaata gagtataatt
    25021 atatttgcac aatagatatc gtttacaaat ccattgtgca aattcttgta ttagctctta
    25081 attacgtaaa aaaatggagg gcatgacatg gaaaattatt atgatgtagc ggtagttggc
    25141 ggtggtccgg ttggacttat gacagcatgt gaattagcta ttcaaggtgt aaaagttgtc
    25201 gttttagaga gaagattaaa tcgaataaga aattctagag cactcacact tcacccccgt
    25261 tccttagaat taatggctat gagaggtatt gaaaatagat ttttatctag agggaagaaa
    25321 tcagatacaa gccattttgc tgccctagat acaagattaa actttaaaaa tctagatact
    25381 gattttccat atacgctttt tattccccaa tctattacag aagaaatatt agaagagcgt
    25441 gcattggaat taggtgtaaa cattaaacgt g
//
