LOCUS       NZ_PVRL01000011        47020 bp    DNA     linear   CON 21-MAY-2024
DEFINITION  Bacillus thuringiensis strain NMTD81
            NODE_11_length_169304_cov_10.5154, whole genome shotgun sequence.
ACCESSION   NZ_PVRL01000011
VERSION     NZ_PVRL01000011.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis
  ORGANISM  Bacillus thuringiensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 169304)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., W,H. and Gao,X.
  TITLE     Genotypic and phenotypic analysis of antagonistic Bacillus spp.
            isolated from rhizosphere soil of plants in Tibet
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 169304)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., W,H. and Gao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) UG, NordReet, Marienstr. 27a, Greifswald
            17489, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. A5-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 14.5x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002998815.1-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 01:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,177
            CDSs (total)                      :: 6,068
            Genes (coding)                    :: 5,840
            CDSs (with protein)               :: 5,840
            Genes (RNA)                       :: 109
            rRNAs                             :: 11, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 1 (5S, 23S)
            partial rRNAs                     :: 6, 5 (16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 228
            CDSs (without protein)            :: 228
            Pseudo Genes (ambiguous residues) :: 0 of 228
            Pseudo Genes (frameshifted)       :: 100 of 228
            Pseudo Genes (incomplete)         :: 142 of 228
            Pseudo Genes (internal stop)      :: 67 of 228
            Pseudo Genes (multiple problems)  :: 63 of 228
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:59:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 62280
            Orig. end                         :: 109300
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVRL01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..47020
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /region_number="2"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..47020
                     /SMILES="NC([*])C(=O)NC(CS)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..47020
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:27020](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..27020)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    401..416
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            699..1916
                     /locus_tag="C6351_RS21875"
                     /old_locus_tag="C6351_21875"
     CDS             699..1916
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709963.1"
                     /locus_tag="C6351_RS21875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21875"
                     /product="macrolide family glycosyltransferase"
                     /protein_id="WP_106082090.1"
                     /sec_met_domain="MGT (E-value: 1.5e-36, bitscore: 120.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKALYINIGGEGHLNPTLGLVHDLVQRGDNIVYYSSNDFEEKIK
                     KAGAQFRPINQEAQRELSETMNLMTSHPQEYLLHFLHAMERITDSIFEEISKETYDYIL
                     YDAQSLPGKWVAHHRGLASIATWTTFAFSQELKENMNLTGTRNIEQKQERLAMLQAFLQ
                     LEEIAKRKQYLEGKYEVSLSDNFLLCPGSGDLNIVFTSRYFQRNSKDFKAGYIFIGPSI
                     AENETLNDFSVDELKGERVIYISMGTIINNQPEFYQKCFVGLKDLNAKVVLSIGKQLIV
                     EQLGDIPDNFIVGNYLPQLDILRQADVFISHCGMNSTSESLYFEVPLVMLPFINDQHTI
                     AERVYELGAGFMLNIQQLSAEDLKHAVNEVLQHSIYKENAKKISQSFREAGGYIKAVDE
                     IVTFTR"
     gene            complement(2351..3010)
                     /locus_tag="C6351_RS21880"
                     /old_locus_tag="C6351_21880"
     CDS             complement(2351..3010)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026528.1"
                     /locus_tag="C6351_RS21880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21880"
                     /product="serine/threonine protein kinase"
                     /protein_id="WP_000026523.1"
                     /transl_table=11
                     /translation="MSINSFVGLIKDELLKEVSIRSEDEFEPVVVKDIPRLWKCLGTGN
                     YAAVFMHREYKDWVVKVYVREGEGIEKESEAYRRIGNHPSYSKLIYKGENFIVLKRLKE
                     ITLYDAIHKGIKIPKQVILDINEALEYAREQGLTPCDVHGKNVMMEKGRGYVVDVSDFL
                     KTKEDSKWRDLEKAYFTFYFPFIYKLPFPVKIPYFMLNIVRRSYRKYKKLKKKFKL"
     gene            complement(3389..3829)
                     /locus_tag="C6351_RS21885"
                     /old_locus_tag="C6351_21885"
     CDS             complement(3389..3829)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202581.1"
                     /locus_tag="C6351_RS21885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21885"
                     /product="NUDIX pyrophosphatase"
                     /protein_id="WP_001202616.1"
                     /transl_table=11
                     /translation="MRAPYQVLIFPYIKTDDSIQYGIFNRSDYGYWQGIAGGGEDGEIP
                     IESAKREAFEEAGITRECPYIQLDSVSSLPVEDVVGGFLWGEEVYVIKEFSFGVKVPTK
                     NISLSKEHFNYKWLCFEEAVTFLKWDSNKTALWELNKRLLKQ"
     gene            complement(4045..5160)
                     /locus_tag="C6351_RS21890"
                     /old_locus_tag="C6351_21890"
     CDS             complement(4045..5160)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844363.1"
                     /locus_tag="C6351_RS21890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21890"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_106082119.1"
                     /sec_met_domain="DAO (E-value: 6.4e-57, bitscore: 187.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYIVVGSGILGASTAYHLAKAGANVTIVDRQQLGQATDAGAGI
                     VCPWLSQRRNKAWYKIVKGGARYYSSLIQQLEEDGETDTGYNRVGAISLHTDEKKLDQI
                     EERAYKRREDAPEIGEITRLSAEETKKLFPALSDEYSSVHISGAARVNGRLLRNALISA
                     AKKHGATFIKGDAILVREGNHITGVIVNDETILAEKVLVTAGAWANEILNPLGINFLVT
                     FQKGQIVHLQIENTATENMPVVMPPNDQYILTFDNGHVVIGATHENDTGFDHRVTAGGL
                     HEVFHKALAVAPGLENATMLETRVGFRPFTPGFLPVIGPLPNFEGILVANGLGASGLTA
                     GPYLGAELAKLALGQPIELDLNDYDVAGAIE"
     gene            complement(5288..5941)
                     /locus_tag="C6351_RS21895"
                     /old_locus_tag="C6351_21895"
     CDS             complement(5288..5941)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017763231.1"
                     /locus_tag="C6351_RS21895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21895"
                     /product="YdeI/OmpD-associated family protein"
                     /protein_id="WP_000110859.1"
                     /transl_table=11
                     /translation="MSVIDKLKLNKYTNMVVINEPSNYDIFTGKETVFSKEHDAIFIFV
                     ETLDEMVKQTNFIISNEELLIEKGYVFFAYPKKGNARYSTFIHRDEMFPALNVGEDGYV
                     GESNIKFARMVSMDEVFTVVGLKREKKKTMKTSAMSQCVADYADRIKDVEALLANHPNE
                     LKFYQSLTPGYQKDWARNLFSVKQEKTREKRLEKMIEILSQGYKTIELFRKKKK"
     gene            complement(6197..6961)
                     /locus_tag="C6351_RS21900"
                     /old_locus_tag="C6351_21900"
     CDS             complement(6197..6961)
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002172112.1"
                     /locus_tag="C6351_RS21900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21900"
                     /product="arylamine N-acetyltransferase"
                     /protein_id="WP_106082091.1"
                     /transl_table=11
                     /translation="MTSLQDQLFARLNLKKRNEVTFEELPTILFSFAHTIPFENLDVIA
                     RNTNQISLENLREKILTSSRGGLCYELNTLFYYFLKDCGYDVQLALGTVYKNDINAWAL
                     EDGHITIILTYANVQYLIDVGIASLVPLVPVPFTDESVSSKNGSYRVRRKDTSKGNYVL
                     ERIDAEGEWKVCHAFYKHIIDEIVVNDVQRRVIEDEKSIFNKGPIAVKLTDSGHVSLTN
                     NSVTEIIYGAKTKREVTEEQYRELLYTLFAIK"
     gene            complement(7101..7604)
                     /locus_tag="C6351_RS21905"
                     /old_locus_tag="C6351_21905"
     CDS             complement(7101..7604)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282282.1"
                     /locus_tag="C6351_RS21905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21905"
                     /product="mep operon protein MepB"
                     /protein_id="WP_001058784.1"
                     /transl_table=11
                     /translation="MNNFNDTIRNLNNIVYQPNNLMITNLKEEKQNAEYAGCLFHLNNK
                     TIRFRKSKVTPNKIGQFVSFWEKDDNMQNQAFSYDAAPDLLVITCIDDHKLGQFILPKE
                     ILLKEKILRTQNQKGKMAMRIYPIWDKPVSNQAKKSQMWQLQYFVDLSDCNNLPIDKLL
                     NLYL"
     gene            complement(7713..8081)
                     /locus_tag="C6351_RS21910"
                     /old_locus_tag="C6351_21910"
     CDS             complement(7713..8081)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403473.1"
                     /locus_tag="C6351_RS21910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21910"
                     /product="DUF4180 domain-containing protein"
                     /protein_id="WP_000351863.1"
                     /transl_table=11
                     /translation="MDIKKVVIDGINIAVIRNDKVLISDVQSALDTMATVQYEVDAKHI
                     IIHKSLISESFFDLKTRLAGDILQKFINYKVKIAIIGEFSIYTSKSLKDFIYECNKGND
                     IFYLATEQQAIEKLSTLK"
     gene            complement(8264..8941)
                     /locus_tag="C6351_RS21915"
                     /old_locus_tag="C6351_21915"
     CDS             complement(8264..8941)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000540708.1"
                     /locus_tag="C6351_RS21915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21915"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_000895699.1"
                     /sec_met_domain="HAD_2 (E-value: 2.1e-32, bitscore: 106.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFDLDDTLLDRDKAVAALFLIVLEKCYENVDGAAKSNMLQKFKE
                     YDKREYGISNKTTVLESLFDEFTPKYRLPRNYIQDFWNNNFPRCFSIDQNTIHFLNQIK
                     KHFKVGIITNGSTQRQKAKIFNTNLNRYFETIIISEEVGFSKPDKRIFELALNKLNLQP
                     ENTLFVGDDLEKDIAGPQNVNIKGVWFNPQKIKNTTKIQPYAEINTLDSLLSYVTPQYF
                     YNK"
     gene            9403..10068
                     /locus_tag="C6351_RS21920"
                     /old_locus_tag="C6351_21920"
     CDS             9403..10068
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002200383.1"
                     /locus_tag="C6351_RS21920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21920"
                     /product="response regulator transcription factor"
                     /protein_id="WP_000800727.1"
                     /transl_table=11
                     /translation="MKNYHILVVEDDQEIQELIKQFLMTQHYTVVVASDGLEGMTQFNK
                     QSFDLILLDVMMPNLNGFEVSKMIRSQSNVPIIMLTALEEEEDQMKGFDLGIDDYITKP
                     FSFHVLIRRVEAVLRRSYDKNVNNHLIFKEVRIDVDAYRVYVNDVEIILTTKEFEILQL
                     LFQNERKVLTRENIVEKVWGYDYFGETRIIDTHIKNLRKKLAIPYIKTIKGIGYKIDE"
     gene            10061..11521
                     /locus_tag="C6351_RS21925"
                     /old_locus_tag="C6351_21925"
     CDS             10061..11521
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084893.1"
                     /locus_tag="C6351_RS21925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21925"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_001084893.1"
                     /transl_table=11
                     /translation="MNSIVKLMKMKQITYKLFMTTSLILLSFAVLIYLTLYFFLPTFYE
                     QYKTDQLQTGINEIIDKSKNLTFQDAIPLFDEYAKKNNAMLYLQNKEGVIIYSPSFSFI
                     QSGTQKTVVTKATRFENASTLSNSYNVTKPIQFQDGSLTLIVFATFQPIDEASQVLVRF
                     LPYISIIVLIIGIGSAYFYSRFITKPLIYINEGAQKMANLDFSEKIEVRSTDELGELSN
                     SLNDMSINLQQAMFDLKKANEQLKNDIEKEREIETKRREFFAIVAHELKSPLTVMKGYL
                     EGMIYNIGPYQNRDQYLKKNHQIIESMEQLVREILSVSKLEQHTFKLKVEEVNPSKLIG
                     TITKDLEFFASQKSIEIIKEFDSDLSIYTDCALLEKACKNIIHNAVMYSPHNEKVYIKL
                     RENSKQDQIEMKIINTGINIKDEDIQQIFKPFYRIEKSRNRNTGGSGLGLYIVKQILET
                     LDIKYSIKNMEHSVQFCMSIPLSKHKNK"
     gene            11849..12385
                     /locus_tag="C6351_RS21930"
                     /old_locus_tag="C6351_21930"
     CDS             11849..12385
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167106.1"
                     /locus_tag="C6351_RS21930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21930"
                     /product="DinB family protein"
                     /protein_id="WP_000405918.1"
                     /transl_table=11
                     /translation="MEIRPKVSEYNSYYATYTNLVSDGNIIHILEQQMKETNLLLKGIS
                     NSKGLFRYAPTKWSIKEVIGHIADTERIMAYRLLSIARGETAELPGYNDDMYVLRAAFD
                     KQSMQDLLENLIVVRQSTLYLLRSLDKEAWSQRGNANNSEVTVRALAYIIAGHELHHLQ
                     IIKERYLGSDAYPAS"
     gene            12587..12769
                     /locus_tag="C6351_RS21935"
                     /old_locus_tag="C6351_21935"
     CDS             12587..12769
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016512708.1"
                     /locus_tag="C6351_RS21935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21935"
                     /product="hypothetical protein"
                     /protein_id="WP_000273237.1"
                     /transl_table=11
                     /translation="MYEQQNNRDRDQKMMFSMQGVPTNKINMNQLPKWIKIFGYCAFGW
                     MIVFSLIMIVGLILQ"
     gene            complement(13069..13746)
                     /locus_tag="C6351_RS21940"
                     /old_locus_tag="C6351_21940"
     CDS             complement(13069..13746)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002085362.1"
                     /locus_tag="C6351_RS21940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21940"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000447864.1"
                     /transl_table=11
                     /translation="METILQFKNLDYYYESNGKNVAILENVNFSFQKGHFYTILGPSGS
                     GKTTTLSLGCGLDVPKNGYVLYNGKDIRKIGLDRYRNQNVSVIFQSYNLITYMTALQNV
                     LTAMEITGVKVQNKTARALQLLERVGLSEAEAKRNVLQLSGGQQQRVAIARALSCNVDL
                     LIADEPTGNLDEETAMDIIELFQELAHKENKCIIVVTHSQEVAKKSDRAVYLSKKKLVV
                     NEI"
     gene            complement(13758..15182)
                     /locus_tag="C6351_RS21945"
                     /old_locus_tag="C6351_21945"
     CDS             complement(13758..15182)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016081356.1"
                     /locus_tag="C6351_RS21945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21945"
                     /product="ABC transporter permease"
                     /protein_id="WP_106082092.1"
                     /transl_table=11
                     /translation="MNFMKRAILSMKKRIGTSLILMAVFLIVTNLVLSGFTIQNASKKA
                     ADAARKKLGADVTLGLDFDKLGQKAKETGEMPNPPQLDAKETDQLAKSKYVKDYNYIAN
                     TFGISDGLKLVGASEEEGKGKVGMAAARGGSSSGTEIDMNASFMIEGVRKTALQESFKN
                     GKSKIIDGKPITEQMKDQNVALMEKRLAELNNLKVGDKVKVQSGDKKETLEVEIIGIYE
                     TNEQAMGQQAPPIMDPANKLYMPHSTMKKLEVDQGISSVQVVYFLNDPQYIDAFKKEAR
                     KFNIDFNYYKLDAHDSLYKQMIGPIENISSTSQMIIYIVSIAGAIILGLIIMLSIKGRR
                     KEMGILLSIGEKKWKLMAQFVVEVVCVAILAFGLSLTTGAKVSQYIGDNLLSNEIATSS
                     EETDTSQHGTVMMAGPGGTLQNQKEDPINKIDVSVTGEDVGKMGGIGLAIAIIATLLPA
                     LSILRLNPKQILLKDE"
     misc_feature    complement(15146..15160)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 24.13"
                     /tool="antismash"
     misc_feature    complement(15312..15327)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.63"
                     /tool="antismash"
     misc_feature    complement(15698..15714)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.69"
                     /tool="antismash"
     gene            15765..16765
                     /locus_tag="C6351_RS21950"
                     /old_locus_tag="C6351_21950"
                     /pseudo=""
     CDS             15765..16765
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577725.1"
                     /locus_tag="C6351_RS21950"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21950"
                     /product="alpha/beta hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIFSKLIDRYALYDLHKKRSVAFQFTSLSNTSLNIKNIESFYKVQ
                     PSHFHFDIKHSKQENEYMVGQFNYKSSVQSGDSRNDSVTGELFLHKNENAPHVIFVHGW
                     RMDSNERVKKYSTII"
     gene            17425..18381
                     /locus_tag="C6351_RS21955"
                     /old_locus_tag="C6351_21955"
     CDS             17425..18381
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001982273.1"
                     /locus_tag="C6351_RS21955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21955"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_000857939.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 4.5e-11, bitscore:
                     36.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTRVNPELLQGLEMFPDLDLRPENLQSIREGIAQMRPPTVVDDS
                     LSLTDKVIVGPDDNPLPLRIYRPKSNHESLPVLLWIHGGGYILGSIDDNDDTCMRFAKE
                     AGCVVVSVDYRLAPEHPYPAPIEDCYSALKWIADNAKSLNIDSNRIGVAGVSAGGGLTA
                     ALSLLARDRKYPSICLQMPLYPMIDDRNDTPSANEIKEGFVWNQKANEAGWKMYLGEMY
                     GTDQIPAYAAPSRAEDYSDLPYTYTFVGQLDPFRSETLTYVSKLAQAGVDVEFHLYPNA
                     YHWFEGLNPNADVSIYAVNEIVQAIKTGFKRVSKVEA"
     gene            complement(18490..19945)
                     /locus_tag="C6351_RS21960"
                     /old_locus_tag="C6351_21960"
                     /pseudo=""
     CDS             complement(18490..19945)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Beta_elim_lyase (137-326). E-value:
                     1.1e-12. Score: 39.7. Matches aSDomain:
                     nrpspksdomains_C6351_RS21960_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129520.1"
                     /locus_tag="C6351_RS21960"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21960"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /pseudo=""
                     /sec_met_domain="Aminotran_5 (E-value: 5.7e-07, bitscore:
                     22.3, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.6e-08, bitscore:
                     26.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKNLQLSAEEMRQLGYQAVDLIVDHMNHLKSKPVSETIDSNIFR
                     DKLIETIPENGSNPKELLHFLNNNVFNQITHVDHPHFMAFVPGPNNYVGVLADFLASGF
                     NVFPTAWIVGAGAEQIELTTINWLKSMLGFPDSAEGLFVSGGSMANLTALTVARQVKLN
                     NDVEKAIVYFSNQTHFSVDRALKVLGFKQHQICRIGTDEDLKISVSTLRKQIKEDRLKG
                     KKPFCVIANAGTTNCGAVDSLNELADLCNDEDIWLHVDGAYGAAAILSEKGRELLSGIH
                     RADSLTLDPHKWLFQPYDVGCVLIRNSQYLSETFRMIPEYIKDTETNIEEKVNFGERGI
                     ELSRRFRALKVWLSFKAFGVTAFREAIDHGIMLAEQVEEFLRKEKDWEVVTPAQLGIVT
                     FRYIPCELTSTDTIHEINKKLVEEINQRGFAMLSTTKLKEKVVIRLCSINPRTTKEEIL
                     QIMMNIKALAEEIKHIA"
     aSDomain        complement(18968..19534)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS21960_Beta_elim_lyase.1"
                     /evalue="1.10E-12"
                     /label="C6351_RS21960_Beta_elim_lyase.1"
                     /locus_tag="C6351_RS21960"
                     /protein_end="326"
                     /protein_start="137"
                     /score="39.7"
                     /tool="antismash"
                     /translation="AEGLFVSGGSMANLTALTVARQVKLNNDVEKAIVYFSNQTHFSVD
                     RALKVLGFKQHQICRIGTDEDLKISVSTLRKQIKEDRLKGKKPFCVIANAGTTNCGAVD
                     SLNELADLCNDEDIWLHVDGAYGAAAILSEKGRELLSGIHRADSLTLDPHKWLFQPYDV
                     GCVLIRNSQYLSETFRMIPEYIKDTE"
     gene            complement(20001..27020)
                     /locus_tag="C6351_RS21965"
                     /old_locus_tag="C6351_21965"
     CDS             complement(20001..27020)
                     /NRPS_PKS="Domain: AMP-binding (269-659). E-value:
                     6.6e-112. Score: 366.0. Matches aSDomain:
                     nrpspksdomains_C6351_RS21965_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (765-831). E-value: 5.9e-16. Score:
                     50.4. Matches aSDomain: nrpspksdomains_C6351_RS21965_PCP.1"
                     /NRPS_PKS="Domain: Heterocyclization (850-1147). E-value:
                     3e-86. Score: 281.4. Matches aSDomain:
                     nrpspksdomains_C6351_RS21965_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (1306-1686). E-value:
                     3.9e-99. Score: 324.0. Matches aSDomain:
                     nrpspksdomains_C6351_RS21965_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1792-1859). E-value: 3.3e-21.
                     Score: 67.2. Matches aSDomain:
                     nrpspksdomains_C6351_RS21965_PCP.2"
                     /NRPS_PKS="Domain: Condensation_DCL (1906-2205). E-value:
                     4.5e-81. Score: 264.2. Matches aSDomain:
                     nrpspksdomains_C6351_RS21965_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547618.1"
                     /locus_tag="C6351_RS21965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21965"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_142399138.1"
                     /sec_met_domain="AMP-binding (E-value: 9.4e-114, bitscore:
                     373.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-13, bitscore:
                     44.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.3e-66, bitscore:
                     216.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHIKDRSSIHENKEVEAFWKEQLSSEILDFSVFKFNSDYQLNKET
                     PCEYVQVRVNVEFSKSIQKISKSQDLLLFSWFQAALRVCLAHYTDQERITIGIPIIEKN
                     LEQSENLNKLIPLGSEIHPHHPFKQLVNEIEQTTLFGYENQEYPLSELLVKHNLTPFQI
                     VIGMEGLHNENSLEEYAENNLVLWIRRKWNEIHNEFEFQISCKSRSFSSLQQFANSYCY
                     VLKQVSQNPNLALKDICIIAEEEEKELLEGLNTFQTGIDLFQSFQDLFEAQVLKTPDQI
                     AVVCNDQSLTYRELNKKANQLASILQSKGVSKESIIGVMVDRSLEMIIGMMGILKAGAA
                     YLPIDPNYPTERIEYMLQDSQAKYLLSKRTEEVLPQFAGEVLYLDKEYLFQGEESNLVR
                     EHNPNDLAYVIYTSGSTGNPKGVMIEQKSLVHFLNVMREKVKANQSFLFLASVSFDISL
                     LEICLPLTQGSKVVIATEDQFATKELAHLVKKHKVDLWESTPSRMEVILSDPEGANFLK
                     DLKSILLAGEAFSIDLVEKIRCISEATILNIYGPTETTICSTVKDLSTSKEVTIGKPNP
                     NYHSYILNKYGQLKPFGIPGELCIAGVAVARGYLGKSKLTDEKFVPSPFTAGEMMYHTG
                     DLVRWLPNGELEYLGRMDHQVKIRGYRIELREIETQLREYPEINQAIVVDQVYGNRKLL
                     AAYYVSDNKVSFGEIRKYLSDKLPEFMIPEKMIQVEEIPLNPNGKVDRKRLLDITQTDY
                     VSIPYVAPRNEIEQKLVCAWEKVMEIEGIGIHDNFFALKGESIKALQVINLLRKDCLKI
                     STTDFFKHPTIAQLSSCVKLEHKEENFESRPTHVKDLSNPFSLTEVQTAYMLGRNSQFE
                     LSGISPQTYFEYETTLDINRLSKSFQKVIHRHPMLRAVILPEGKQQILQSVPDYQIEIV
                     SLIDLDDRNQNARLQEERSRMTNHVFPLGQWPLFELKAFLLKEDTYLLCFRYDALLMDG
                     ASMNIVGQDLLHYYYKPNQRLESLSFDFQDYMFIYDEMKQIGEYKTAKDYWTSKLPDFP
                     FAPSLLLKKDPAEIATPKFQSLTKILDNEKWTKLRKLAQEKEVTPSALLCTIYGDVLAY
                     WSNQRRLAINLTVFNRYPVHDEVEQIVGDFTSLILLDVDVKPEQTFFTRVKETQSTLLD
                     GLEHRHYDGVNFIRDFTRYHQMTPKAVMPIVFTSMLAGAGAFSWEQLGSLRYIHARTPQ
                     VYLDNVVIEKNGELLISWNYVEELFDIDVIEAMFSQFVDLLEQLVKQSDITSLQMKESD
                     QTLIEQYNETTEKIPSTTLYQLFTDQVKRTPNEVAVVFEQKWLTYSELHKRSNQIAHFL
                     KEQGIGLGDKVGLLAKRRVDTIVNMLGILKVGAAYVPIDPDHPLDRQTYILKNSSCKLL
                     LEPSLYEENDLSFYTTEDMPAIAGPEDIAYIIYTSGSTGKPKGVIITHQAVTNTIQDIN
                     QKYEVNEDDRIIGISSMCFDLSVYDIFGALSTGAMLVMIRDPRDMQELIRTVERRGITI
                     WNTVPAIMDLALDQVGSHFEHSSLRLVLHSGDWIPLSLPEKIKRHFPIAEVVSLGGATE
                     ASIWSIYYPVKQVESHWNSIPYGMPLANQTYYVLNYEKKMCPVGVTGDLYIGGVGLAKG
                     YLNDEKKTNEAFVSHPDFGLIYKTGDCGKMHSEGYIEFLGRQDYQVKIQGYRVELEEIA
                     HCLLTYKQVEHAVVIDQTDENGIKFLVAYVVTEQNISTTELRKHLRDHLPDYMIPSYFV
                     YLDQLPLTPNGKLDRKALPTPEKQTNEVFIAPKTEMEKILTSIWQEVLKIDQVGVNDHF
                     FALGGDSIRAIQVSVRLYRQGFELEPKNLFSFPILRDMVQFVKKLDHFSSSQTNDVNIM
                     NDNKATLLNIKDKQLNQQTLTKIQEKMPDIKIERIYPLAPFQEVIYEHATNEPDTNAYF
                     EQTIWALEGELDIKLFIQCFQQLVDRHDSLRTIIVQDEQAKPWQAVLYDVQINSEIKNL
                     IEMTKQEQQEFLKQWMNENLSRGFKNDELMTRLCIFQLGNNEHKVIWSSHHLLCDGWSV
                     SILIDELFQLYETTNAGTTAGLPIVKPFETFIDWTLVQDHEKARHFWRDYLSGYNQKIS
                     IPKKKVPSKSEGLNFTFMDLTLDKDLTNQLQTFVTKNNITMNTALLAVWGILLGKFNGT
                     REVVLPNLVSVRPPEVEGIESMFGLFTNVLPIRLAWTETQSFVDFLQKVQLETLKCNEY
                     AYYSFVDIQKQSELKTELTDHLWVFENYPTNPAIFSSNENRHFAITDYEVVDEPHVKYG
                     IMCFPEEKLTIKFGYDQTLYEAKKIQEILNHIHCLINTILQNPIQTICDYKL"
     CDS_motif       complement(20250..20345)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0020"
                     /evalue="1.30E-10"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="C6351_RS21965"
                     /protein_end="2257"
                     /protein_start="2225"
                     /score="33.6"
                     /tool="antismash"
                     /translation="NEYAYYSFVDIQKQSELKTELTDHLWVFENYP"
     aSDomain        complement(20406..21302)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS21965_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="4.50E-81"
                     /label="C6351_RS21965_Condensation_DCL.1"
                     /locus_tag="C6351_RS21965"
                     /protein_end="2205"
                     /protein_start="1906"
                     /score="264.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLLCDG"
                     /tool="antismash"
                     /translation="ERIYPLAPFQEVIYEHATNEPDTNAYFEQTIWALEGELDIKLFIQ
                     CFQQLVDRHDSLRTIIVQDEQAKPWQAVLYDVQINSEIKNLIEMTKQEQQEFLKQWMNE
                     NLSRGFKNDELMTRLCIFQLGNNEHKVIWSSHHLLCDGWSVSILIDELFQLYETTNAGT
                     TAGLPIVKPFETFIDWTLVQDHEKARHFWRDYLSGYNQKISIPKKKVPSKSEGLNFTFM
                     DLTLDKDLTNQLQTFVTKNNITMNTALLAVWGILLGKFNGTREVVLPNLVSVRPPEVEG
                     IESMFGLFTNVLPIRLAW"
     CDS_motif       complement(20415..20489)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0019"
                     /evalue="3.80E-09"
                     /label="C5_DCL_263-294"
                     /locus_tag="C6351_RS21965"
                     /protein_end="2202"
                     /protein_start="2177"
                     /score="29.0"
                     /tool="antismash"
                     /translation="VSVRPPEVEGIESMFGLFTNVLPIR"
     CDS_motif       complement(20544..20579)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0018"
                     /evalue="1.70E+01"
                     /label="Cy4"
                     /locus_tag="C6351_RS21965"
                     /protein_end="2159"
                     /protein_start="2147"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="NITMNTALLAVW"
     CDS_motif       complement(20835..20897)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0017"
                     /evalue="1.30E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="C6351_RS21965"
                     /protein_end="2062"
                     /protein_start="2041"
                     /score="33.7"
                     /tool="antismash"
                     /translation="HHLLCDGWSVSILIDELFQLY"
     CDS_motif       complement(21114..21230)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0016"
                     /evalue="2.40E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1969"
                     /protein_start="1930"
                     /score="48.8"
                     /tool="antismash"
                     /translation="AYFEQTIWALEGELDIKLFIQCFQQLVDRHDSLRTIIVQ"
     aSDomain        complement(21444..21644)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS21965_PCP.2"
                     /evalue="3.30E-21"
                     /label="C6351_RS21965_PCP.2"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1859"
                     /protein_start="1792"
                     /score="67.2"
                     /tool="antismash"
                     /translation="EKILTSIWQEVLKIDQVGVNDHFFALGGDSIRAIQVSVRLYRQGF
                     ELEPKNLFSFPILRDMVQFVKK"
     aSModule        complement(21444..24470)
                     /complete
                     /domains="nrpspksdomains_C6351_RS21965_Heterocyclization.1"
                     /domains="nrpspksdomains_C6351_RS21965_AMP-binding.2"
                     /domains="nrpspksdomains_C6351_RS21965_PCP.2"
                     /locus_tags="C6351_RS21965"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(21933..21995)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0015"
                     /evalue="2.70E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1696"
                     /protein_start="1675"
                     /score="26.1"
                     /tool="antismash"
                     /translation="FLGRQDYQVKIQGYRVELEEI"
     aSDomain        complement(21963..23102)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS21965_AMP-binding.2"
                     /evalue="3.90E-99"
                     /label="C6351_RS21965_AMP-binding.2"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1686"
                     /protein_start="1306"
                     /score="324.0"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FTDQVKRTPNEVAVVFEQKWLTYSELHKRSNQIAHFLKEQGIGLG
                     DKVGLLAKRRVDTIVNMLGILKVGAAYVPIDPDHPLDRQTYILKNSSCKLLLEPSLYEE
                     NDLSFYTTEDMPAIAGPEDIAYIIYTSGSTGKPKGVIITHQAVTNTIQDINQKYEVNED
                     DRIIGISSMCFDLSVYDIFGALSTGAMLVMIRDPRDMQELIRTVERRGITIWNTVPAIM
                     DLALDQVGSHFEHSSLRLVLHSGDWIPLSLPEKIKRHFPIAEVVSLGGATEASIWSIYY
                     PVKQVESHWNSIPYGMPLANQTYYVLNYEKKMCPVGVTGDLYIGGVGLAKGYLNDEKKT
                     NEAFVSHPDFGLIYKTGDCGKMHSEGYIEFLGRQDYQVKI"
     CDS_motif       complement(22071..22160)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0014"
                     /evalue="1.90E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1650"
                     /protein_start="1620"
                     /score="42.5"
                     /tool="antismash"
                     /translation="PVGVTGDLYIGGVGLAKGYLNDEKKTNEAF"
     CDS_motif       complement(22671..22730)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0013"
                     /evalue="2.80E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1450"
                     /protein_start="1430"
                     /score="32.0"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVIITH"
     CDS_motif       complement(22875..22916)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0012"
                     /evalue="6.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1382"
                     /protein_start="1368"
                     /score="16.2"
                     /tool="antismash"
                     /translation="LGILKVGAAYVPID"
     CDS_motif       complement(23313..23357)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0011"
                     /evalue="2.50E-03"
                     /label="Cy7"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1236"
                     /protein_start="1221"
                     /score="11.1"
                     /tool="antismash"
                     /translation="RTPQVYLDNVVIEKN"
     CDS_motif       complement(23478..23519)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0010"
                     /evalue="1.30E-03"
                     /label="afterCy5"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1181"
                     /protein_start="1167"
                     /score="11.8"
                     /tool="antismash"
                     /translation="LEHRHYDGVNFIRD"
     aSDomain        complement(23580..24470)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS21965_Heterocyclization.
                     1"
                     /evalue="3.00E-86"
                     /label="C6351_RS21965_Heterocyclization.1"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1147"
                     /protein_start="850"
                     /score="281.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DALLMDG"
                     /tool="antismash"
                     /translation="NPFSLTEVQTAYMLGRNSQFELSGISPQTYFEYETTLDINRLSKS
                     FQKVIHRHPMLRAVILPEGKQQILQSVPDYQIEIVSLIDLDDRNQNARLQEERSRMTNH
                     VFPLGQWPLFELKAFLLKEDTYLLCFRYDALLMDGASMNIVGQDLLHYYYKPNQRLESL
                     SFDFQDYMFIYDEMKQIGEYKTAKDYWTSKLPDFPFAPSLLLKKDPAEIATPKFQSLTK
                     ILDNEKWTKLRKLAQEKEVTPSALLCTIYGDVLAYWSNQRRLAINLTVFNRYPVHDEVE
                     QIVGDFTSLILLDVDV"
     CDS_motif       complement(23583..23642)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0009"
                     /evalue="8.70E-09"
                     /label="Cy5"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1146"
                     /protein_start="1126"
                     /score="27.5"
                     /tool="antismash"
                     /translation="HDEVEQIVGDFTSLILLDVD"
     CDS_motif       complement(23643..23678)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0008"
                     /evalue="3.40E-03"
                     /label="afterCy4"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1126"
                     /protein_start="1114"
                     /score="10.3"
                     /tool="antismash"
                     /translation="AINLTVFNRYPV"
     CDS_motif       complement(23694..23750)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0007"
                     /evalue="1.40E-08"
                     /label="Cy4"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1109"
                     /protein_start="1090"
                     /score="27.4"
                     /tool="antismash"
                     /translation="VTPSALLCTIYGDVLAYWS"
     CDS_motif       complement(24012..24068)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0006"
                     /evalue="4.40E-04"
                     /label="C3_DCL_135-156"
                     /locus_tag="C6351_RS21965"
                     /protein_end="1003"
                     /protein_start="984"
                     /score="13.0"
                     /tool="antismash"
                     /translation="LLMDGASMNIVGQDLLHYY"
     CDS_motif       complement(24273..24326)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0005"
                     /evalue="2.40E-08"
                     /label="Cy2"
                     /locus_tag="C6351_RS21965"
                     /protein_end="916"
                     /protein_start="898"
                     /score="26.2"
                     /tool="antismash"
                     /translation="VIHRHPMLRAVILPEGKQ"
     aSDomain        complement(24528..24725)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS21965_PCP.1"
                     /evalue="5.90E-16"
                     /label="C6351_RS21965_PCP.1"
                     /locus_tag="C6351_RS21965"
                     /protein_end="831"
                     /protein_start="765"
                     /score="50.4"
                     /tool="antismash"
                     /translation="EQKLVCAWEKVMEIEGIGIHDNFFALKGESIKALQVINLLRKDCL
                     KISTTDFFKHPTIAQLSSCVK"
     aSModule        complement(24528..26213)
                     /complete
                     /domains="nrpspksdomains_C6351_RS21965_AMP-binding.1"
                     /domains="nrpspksdomains_C6351_RS21965_PCP.1"
                     /locus_tags="C6351_RS21965"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(25014..25079)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0004"
                     /evalue="1.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="C6351_RS21965"
                     /protein_end="669"
                     /protein_start="647"
                     /score="36.5"
                     /tool="antismash"
                     /translation="YLGRMDHQVKIRGYRIELREIE"
     aSDomain        complement(25044..26213)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS21965_AMP-binding.1"
                     /evalue="6.60E-112"
                     /label="C6351_RS21965_AMP-binding.1"
                     /locus_tag="C6351_RS21965"
                     /protein_end="659"
                     /protein_start="269"
                     /score="366.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEAQVLKTPDQIAVVCNDQSLTYRELNKKANQLASILQSKGVSKE
                     SIIGVMVDRSLEMIIGMMGILKAGAAYLPIDPNYPTERIEYMLQDSQAKYLLSKRTEEV
                     LPQFAGEVLYLDKEYLFQGEESNLVREHNPNDLAYVIYTSGSTGNPKGVMIEQKSLVHF
                     LNVMREKVKANQSFLFLASVSFDISLLEICLPLTQGSKVVIATEDQFATKELAHLVKKH
                     KVDLWESTPSRMEVILSDPEGANFLKDLKSILLAGEAFSIDLVEKIRCISEATILNIYG
                     PTETTICSTVKDLSTSKEVTIGKPNPNYHSYILNKYGQLKPFGIPGELCIAGVAVARGY
                     LGKSKLTDEKFVPSPFTAGEMMYHTGDLVRWLPNGELEYLGRMDHQVKIR"
     CDS_motif       complement(25161..25250)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0003"
                     /evalue="3.70E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="C6351_RS21965"
                     /protein_end="620"
                     /protein_start="590"
                     /score="38.4"
                     /tool="antismash"
                     /translation="PFGIPGELCIAGVAVARGYLGKSKLTDEKF"
     CDS_motif       complement(25746..25802)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0002"
                     /evalue="4.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="C6351_RS21965"
                     /protein_end="425"
                     /protein_start="406"
                     /score="31.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGNPKGVMIE"
     CDS_motif       complement(25986..26027)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C6351_RS21965_0001"
                     /evalue="4.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="C6351_RS21965"
                     /protein_end="345"
                     /protein_start="331"
                     /score="16.8"
                     /tool="antismash"
                     /translation="MGILKAGAAYLPID"
     gene            complement(27053..28030)
                     /locus_tag="C6351_RS21970"
                     /old_locus_tag="C6351_21970"
     CDS             complement(27053..28030)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290962.1"
                     /locus_tag="C6351_RS21970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21970"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_142398845.1"
                     /sec_met_domain="PF00881 (E-value: 7.3e-26, bitscore: 84.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKIYYWSPIKHWEKLHNEVLIGEMRFTGILSEWFPDLYFMAQK
                     GVKISELVERFSLGNVEETQKNIELMIKNRVLVSNILHPREVFSSQEKIFSNPYSNQIR
                     FSKEKLDKYMSEQLNRTHVAARSTEIQLETTNELPTIIKERRSCRQFDMEKHISFSEFS
                     QFLSTLKQVREEKIYYHYASAGGLYPIDIFVYIKPKRIEGMKAGFYYYNPSKNSLVIVN
                     NIDQVIKSDHELINQDLFTQSAFSVYLIYNANASIPKYGSDGYLFACIESGIITATLNM
                     VAETLNLGVCSVGHMKFEDIQQFLCLDNQQVFLHGLEVGLKINE"
     misc_feature    28763..28779
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: medium, score: 28.23"
                     /tool="antismash"
     gene            complement(28902..31460)
                     /gene="pulA"
                     /locus_tag="C6351_RS21975"
                     /old_locus_tag="C6351_21975"
     CDS             complement(28902..31460)
                     /EC_number="3.2.1.41"
                     /GO_function="GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pulA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167496.1"
                     /locus_tag="C6351_RS21975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21975"
                     /product="type I pullulanase"
                     /protein_id="WP_142398844.1"
                     /sec_met_domain="CBM_48 (E-value: 1.1e-15, bitscore: 51.2,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 1.5e-13, bitscore:
                     44.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIIKRLINKTVLLLTLIVMLSSVFSFQGVKAVSNSKTTEVIIHY
                     KEKLGNTKDWNLWLWGENANGTSYEFTGEDEFGKYAKIKIDGDYNRVGFIVRTNEWEKD
                     GGDRWIENIKGGRAEVWILSGDEKVYNSKPSSDLSIQKATIDSFHEITITTNVPFHIRE
                     KKIEIEGIKIKNISPYDINSGDITNKVKIITEQKIDLKQTYKVKIENLADTNTEIGKVI
                     RSEEFDNLFYYSGNDLGNTYTAQHTKFRLWAPTASEAKLVTYKNWNDKIGAEINMQQGE
                     KGTWTAELKGNQKGLFYTYKVKIGDTWTEAVDPYVRAASVNGDKGAVVNLEETNPKKWK
                     ANKKPKFKNPEDAIIYELHVRDLSIQPESGIKQKGKYLGVTEKGTKGPEGVKTGLDHIK
                     DLGVTHVQFLPIFDYASVNEETLNEPQYNWGYDPKNFNVPEGSYSTNPYEPTFRITELK
                     QMVQILHDNNLRVVMDVVYNHMYNAAESNFHKLVPGYYYRYNEDGTFANGTGVGNDTAS
                     ERKMMRKFMIDSVTYWAKEYNLDGFRFDLMGIHDYETMNEIRKAVNQIDPSIILHGEGW
                     DLNTPLAAELKANQKNAEKMKGIAHFNDNIRDGLKGSVFEEKENGFINGKENMEDRIKK
                     GITAGIDYDTNSSTYQDPEQVLTYVEAHDNHTLWDKLELTNSGDSEEVRKQMHKLSSSI
                     LLTSQGIPFLHAGQEFMRTKYGDHNSYKSPDSINQMDWLRRATFNNEVDYMKGLIELRK
                     KYSAFRMTSAEQIKTHVSFIDAPKNTVAYTIEGNKNEYFTVAHNANREAVEITLPSKGP
                     WKVLVDSKQAGSKPLYVVHDNKIKVPTLSSFVLKTEKPIK"
     misc_feature    complement(31703..31714)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            complement(31941..33644)
                     /locus_tag="C6351_RS21980"
                     /old_locus_tag="C6351_21980"
     CDS             complement(31941..33644)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791466.1"
                     /locus_tag="C6351_RS21980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21980"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_000791462.1"
                     /transl_table=11
                     /translation="MKNKKTLTKVALTTGLALTAVAPYGVGHAEETDQLQVQIQEESFR
                     SGELTQPSQKTPENVVKDALKEKTEQALSQKQVNGEAGVDYKVLQKRGSYDGTTLVRMQ
                     QTYEGKEVYGHQLTAHVDNNGVIKSVSGDSAQNLKQEELKKPINLSKDEAKQFIYTKYG
                     NDIKFITEPEVKEVIFVDENNGQAKNAYQVTFEAATPNYVSGTYLVNAQNGDMLKNMVQ
                     ESNLKASDKLVGALKKSKQSSLTSLTGTGKDDLGISRSFGISKQSNGKYALADYTRGQG
                     IETYDVNYRDITKEESYYPGTLATSTSATFNDPKAVSAHYLATKVFDFYKDKYKRNSFD
                     NKGQKVVSVVHAWDSEETNDPKNWQNALSANNGSMLVYGDPIVKAYDVAGHEFTHAVTS
                     SESNLEYYGESGAINEALSDIMGTSIEKYVNNGNFNWTMGEQTGSVFRDMENPASVPSS
                     LGVPYPDDYSEFNDFNGWDQGGVHFNSSIINKVAYLIAKGGTHNGVTVKGIGEDKMFDI
                     FYYANTDELNMTSNFKELKSACIRVATNKYGANTAEVQAVQKAFDAAKIK"
     gene            complement(33985..35937)
                     /locus_tag="C6351_RS21985"
                     /old_locus_tag="C6351_21985"
     CDS             complement(33985..35937)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009166 - nucleotide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014895270.1"
                     /locus_tag="C6351_RS21985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21985"
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="WP_016098602.1"
                     /transl_table=11
                     /translation="MQKMKWKNYVCYFVILLLLGTAVIVKPPISKAEESEVNITLLGTA
                     DIHGRFMPWDYALDGANMSGSLTQLYTVIKKVRQENQNTILVDAGDTIQGNSVELFNDK
                     PQSPMMVAMNTMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAGNIYKENGERFLPAY
                     TIVEKGGIKVGIIGMNTPMISDFEKGTDHLNGLVVKNPVEETKKAIKELEGKVDVMVGV
                     MHMGLENENGIPGTGVQDIANACPELSAIFAAHMHKLVKKEVVNGVIITEPDKYGTHIS
                     RIDLTFTKQDEKLVLKDKTATAIPVKNADGTTILSDPTLEETLTPFHEYARGDANVVVA
                     QLKGRNLVPENEIKGIPSVQIQETPLSDFFHEVMLYYSKADVVAHQIDNDYARLDTGPI
                     KKKDIAYNYQYALGEITVYKISGKDLKDYMEWAAGYFNSSRAGDVTVSFDKTRRASKYS
                     TNDFFGGVKYEIDLTKPYGSRITNLRSIRTNKPIKMSDVMTLGMNAYRMEALQAKGGAL
                     EGRKFEQIWSSKQENAFGETGGTIRNLAITYLKEVKNGVYTPKVMRNWKITGVDLHSSE
                     HKAVVDLVNKGILEIPKTEDGKYTNIASINTKDSITKEEIVALSQKANINPNQFKHIKT
                     KGEFYKKLSRITKKI"
     gene            complement(36465..36980)
                     /locus_tag="C6351_RS21990"
                     /old_locus_tag="C6351_21990"
     CDS             complement(36465..36980)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379366.1"
                     /locus_tag="C6351_RS21990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21990"
                     /product="DinB family protein"
                     /protein_id="WP_000379381.1"
                     /transl_table=11
                     /translation="MDTFVNNKFYETRNQLVEEINLLSDAQFNRKPDKDKWSIAQVCHH
                     LVLLDERIITVISSGLKKLDSTQNERKEIHTILLDRTKKFIAPEMIEPSIEPFEVLQMV
                     DLLNDSRKELMRFLSTIEDESKLVKKSVMHPALGELFLDQWIELIYLHEQRHIEQIKEI
                     KLLCEIEK"
     gene            complement(37064..37585)
                     /locus_tag="C6351_RS21995"
                     /old_locus_tag="C6351_21995"
     CDS             complement(37064..37585)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869615.1"
                     /locus_tag="C6351_RS21995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_21995"
                     /product="GyrI-like domain-containing protein"
                     /protein_id="WP_106082097.1"
                     /transl_table=11
                     /translation="MKVVIKKLPPLEVAYIRRTGSYFEPQNHWGKLLNWSIENNLYPPE
                     QSFIGISLDNPELVASHKCRHDACVTIPENFDKEKYHDVQFKRLDGGTYGLYQFYGEPH
                     KLSEAYQYMYAEWLLNSEYDADYDRDNLEFCLNNVAEDLEGKLKVDLFVPIKNIQKTNN
                     FICGFKMKLE"
     misc_feature    37559..37575
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.46"
                     /tool="antismash"
     gene            37834..38301
                     /locus_tag="C6351_RS22005"
                     /old_locus_tag="C6351_22005"
     CDS             37834..38301
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000589637.1"
                     /locus_tag="C6351_RS22005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_22005"
                     /product="VOC family protein"
                     /protein_id="WP_000589638.1"
                     /transl_table=11
                     /translation="MIKGIYEAHLPVSNLQQSIEFYEKLGLKLAWSDESTAFFWIEDGK
                     SWLGLWAGSEYETKYHPSLRHIAFRVSYEDLKESLHWLHSLQIKTVPFGSNESIEPFVR
                     PHQGNASVYFIDPDGNSLELICHIVVPNALKHITNKLSFKDWETLLADTFE"
     gene            38656..39960
                     /gene="secY"
                     /locus_tag="C6351_RS22010"
                     /old_locus_tag="C6351_22010"
     CDS             38656..39960
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /gene="secY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016091122.1"
                     /locus_tag="C6351_RS22010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_22010"
                     /product="preprotein translocase subunit SecY"
                     /protein_id="WP_000490132.1"
                     /transl_table=11
                     /translation="MFRTISNFMRVAEIRRKILFTLAMLIVFRIGTFIPVPHTNAEVLK
                     VQDQANVLGMLNVFGGGALQHFSIFAVGITPYITASIIVQLLQMDVIPKFSEWAKQGEM
                     GRKKSAQFTRYFTIILAFIQAIGMSYGFNNIAGGQLITDQSWTTYLFIATVLTAGTAFL
                     LWLGEQITANGVGNGISMIIFAGLVAAIPNVANQIYLQQFQNAGDQLFMHIIKIVLIGL
                     VILAIVVGVIYIQQAVRKIPIQYAKAVSGNNQYQGAKNTHLPLKVNSAGVIPVIFASAF
                     LMTPRTIAQLFPDSSISKWLVANLDFAHPIGMTLYVGLIVAFTYFYAFIQVNPEQMAEN
                     LKKQNGYVPGIRPGKATEQYVTKILYRLTFIGAIFLGAISILPLVFTKIATLPPSAQIG
                     GTSLLIIVGVALETMKTLESQLVKRHYKGFIKKVN"
     gene            complement(40046..40963)
                     /locus_tag="C6351_RS22015"
                     /old_locus_tag="C6351_22015"
     CDS             complement(40046..40963)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234336.1"
                     /locus_tag="C6351_RS22015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_22015"
                     /product="EamA family transporter"
                     /protein_id="WP_000234334.1"
                     /transl_table=11
                     /translation="MVIFNYILVCIIFGTTFLTIKIGIEAGAPPLFSAGIRFFLAGIIL
                     MIIFKLKRKEIMPHIFSKRIMYAGFCLTFMTFASLYWSEQYISSGLAAVLSATGPMMIL
                     LIQAKRNREKLQKEQLVALVIALIGVIFVSLPGMHQQVSFIWSIACIVLVIGELFYGIG
                     SIRSKEILSDLSNVSPFLINGIQMFYGGILLLIASIIVEQPNVSVLTSWSVQWPILYLI
                     FIGSIGGHGLYYWLLSKTNPVFPSTWLYVSPLIAIIVGYIILGEPLNPTMGMGACFILI
                     GVFLTNRSTLRTYFKKGRLLEKEM"
     gene            41112..42545
                     /locus_tag="C6351_RS22020"
                     /old_locus_tag="C6351_22020"
     CDS             41112..42545
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (144-468). E-value:
                     4.1e-36. Score: 116.8. Matches aSDomain:
                     nrpspksdomains_C6351_RS22020_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706793.1"
                     /locus_tag="C6351_RS22020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_22020"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_000706776.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.3e-35, bitscore:
                     116.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIVLRKESNIPYYKQIYMQIVERVQSGMLSHGESLPSLRCMATD
                     LQINVLTVRKAYKQLETKGYIRIEQGKGAYIYKRVKKDFKPIPYKWQQSRSINVMRSQY
                     AMNKHRKYYDFSQAILYPRLLPNPFLADEMHKLLDKNPMLLATYGPVQGDYELRVEIAN
                     YLNEHQKLVTDPSQLLITSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDVFINKGVQ
                     IIPISLDNHGVRSDLIDDICQSKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYQF
                     FIIEDDSFGEIYFEGAIVPPPIKSFDKDGHVIYIKGFSKTLAPGLRIAVLFADGPIFEW
                     LYAVKGSMDIGSPLLTQKALLPFLRAERMKNHLEKLRTALQMRRDLTIDILSPLKGLNF
                     EIPNGGFNLWVTLPDWIDPFTLLQKANEVDVSFLPGTACLLNYETNDNQLRISYSMLNE
                     KDMAIGLEKLHDTIRNSIC"
     aSDomain        41544..42515
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS22020_Aminotran_1_2.1"
                     /evalue="4.10E-36"
                     /label="C6351_RS22020_Aminotran_1_2.1"
                     /locus_tag="C6351_RS22020"
                     /protein_end="468"
                     /protein_start="144"
                     /score="116.8"
                     /tool="antismash"
                     /translation="LATYGPVQGDYELRVEIANYLNEHQKLVTDPSQLLITSGAQQGID
                     LIAQTLLKPGDIVLVESPCYSAALDVFINKGVQIIPISLDNHGVRSDLIDDICQSKNPV
                     LLYTNPTFQNPTGTVMSKERRMELIELAELYQFFIIEDDSFGEIYFEGAIVPPPIKSFD
                     KDGHVIYIKGFSKTLAPGLRIAVLFADGPIFEWLYAVKGSMDIGSPLLTQKALLPFLRA
                     ERMKNHLEKLRTALQMRRDLTIDILSPLKGLNFEIPNGGFNLWVTLPDWIDPFTLLQKA
                     NEVDVSFLPGTACLLNYETNDNQLRISYSMLNEKDMAIGLEKL"
     misc_feature    complement(42707..42718)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     gene            42969..43823
                     /locus_tag="C6351_RS22025"
                     /old_locus_tag="C6351_22025"
     CDS             42969..43823
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (23-268). E-value:
                     7.8e-25. Score: 79.8. Matches aSDomain:
                     nrpspksdomains_C6351_RS22025_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290766.1"
                     /locus_tag="C6351_RS22025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_22025"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_001290769.1"
                     /sec_met_domain="PF00561 (E-value: 1.6e-21, bitscore: 70.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.8e-12, bitscore:
                     40.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKIFKINGIDICTESFGNPKNPAILLIMGATCSMVYWDEEFCE
                     LLASTGKFVIRFDNRDVGRSVAYEPRTSNYTVTDMAEDAIGVLDAYHIDKAHLFGMSLG
                     GMIAQIAAIKHPERILTLTLLATSVIGSDDNTRDLPPMDERILTHHVNGTSIDWTNKND
                     VAEYLVSGSRLLCGSERIFDENRVYTQVKQEIERANNLLSMFNHALLQGDDAYEGVLHS
                     IQAPTLVIHGTDDTALPFEHGLALIDEIPNSVLLTLKGAGHENHPDDWESIITAVSKHT
                     SEI"
     aSDomain        43038..43772
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C6351_RS22025_Abhydrolase_1.1"
                     /evalue="7.80E-25"
                     /label="C6351_RS22025_Abhydrolase_1.1"
                     /locus_tag="C6351_RS22025"
                     /protein_end="268"
                     /protein_start="23"
                     /score="79.8"
                     /tool="antismash"
                     /translation="PAILLIMGATCSMVYWDEEFCELLASTGKFVIRFDNRDVGRSVAY
                     EPRTSNYTVTDMAEDAIGVLDAYHIDKAHLFGMSLGGMIAQIAAIKHPERILTLTLLAT
                     SVIGSDDNTRDLPPMDERILTHHVNGTSIDWTNKNDVAEYLVSGSRLLCGSERIFDENR
                     VYTQVKQEIERANNLLSMFNHALLQGDDAYEGVLHSIQAPTLVIHGTDDTALPFEHGLA
                     LIDEIPNSVLLTLKGAGHENHPD"
     gene            complement(43941..44276)
                     /locus_tag="C6351_RS22030"
                     /old_locus_tag="C6351_22030"
     CDS             complement(43941..44276)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002147461.1"
                     /locus_tag="C6351_RS22030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_22030"
                     /product="hypothetical protein"
                     /protein_id="WP_001257762.1"
                     /transl_table=11
                     /translation="MRSRRYKRGDRVKINIHKSVSPEMLAWLNKQSNPTNFFFFAAQQL
                     FKQVGDIDVSKALPSSHVFSLYVEPSSLLKVEVNPFKNMTLETNTSTENAKKKLWESVD
                     QLDCPFF"
     misc_feature    44260..44277
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.36"
                     /tool="antismash"
     gene            complement(44288..45457)
                     /locus_tag="C6351_RS22035"
                     /old_locus_tag="C6351_22035"
     CDS             complement(44288..45457)
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002013097.1"
                     /locus_tag="C6351_RS22035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_22035"
                     /product="ParM/StbA family protein"
                     /protein_id="WP_086398318.1"
                     /transl_table=11
                     /translation="MSILLKAGADAGNNGLKLMVKGQDPIFIPSIYSLYIGEPTGLLDE
                     VDVSLSELENHIDVTISSPSLMLNNVRYIVGEKVIQDQLKGTEVEKKSNKSTDELMVIT
                     ILSGLAVSAMRQSPTSSHINIRYDLSVALPMQLITQEIAAENAKRYMGNHKVIFHYPNG
                     RDVTINVSIEYCKCLPEGASGTWGIVYDEEGNVVKHKIECEPNQVSEIDFVDKTLLSFD
                     IGAGTTEEVVSLGVNFRPQLSKGLSYGVKETLLQIITRWNRKYPTKTIDSITEFNQIYL
                     NDKHPRNTLLVEESQPALLGLAARVATDIINKIDDMKDDPYVFIYGGGAVIIKNSLKMI
                     LKQKGRLKNVIFVDNPLFTNARGLLVYTCSPKYREHKQKELGFTNLTIS"
     misc_feature    45410..45423
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.66"
                     /tool="antismash"
     gene            45667..46071
                     /locus_tag="C6351_RS22040"
                     /old_locus_tag="C6351_22040"
     CDS             45667..46071
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129600.1"
                     /locus_tag="C6351_RS22040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_22040"
                     /product="hypothetical protein"
                     /protein_id="WP_001093135.1"
                     /transl_table=11
                     /translation="MNTKKTIFIIIVLALIAIIVHGTYKYITEGSILGGTIFAISLILS
                     NLINHITWGDPHGVSEESQDEMGQQITYKSFKIAYFVLVVIMFLLLIFSEGFSMGANLD
                     GVKNLPLFIAICSSFFIYPIVELIVAKQYK"
     gene            complement(46116..46652)
                     /locus_tag="C6351_RS22045"
                     /old_locus_tag="C6351_22045"
     CDS             complement(46116..46652)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016122631.1"
                     /locus_tag="C6351_RS22045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_22045"
                     /product="DUF1697 domain-containing protein"
                     /protein_id="WP_000158574.1"
                     /transl_table=11
                     /translation="MTIYVALLRGINVGGHKVIKMADLKRLFESIELKHVKTYIQSGNI
                     VFESEEGINFLKDRIQSEMKNEFDFDVPVMLRTHDEFINIIKQCPYEVHSLLEGESVHV
                     AFLANVLSEEESSQLLTFKSELEDCYIDEKVAYLFFKNSIRNSKLMNQFQKLHTPATVR
                     NWRTVNKLKAIVESM"
ORIGIN
        1 gttggtgttg tatataacag ggaacttcca gctattaaaa gggccagact tgcacatgta
       61 atttgactac gtattttcat aaggcattcc tctcctctat tcatattgta taagtgcttg
      121 ctgttcctta cttcctaaca agacttaggg aaaggccctc acgcatatag attaaagccc
      181 cagtacaaag gtatatatca ataccaacaa tttgagccat ttaaatctcc atcccttcta
      241 taacaaaatt attcaaaggt atgaaagcat attatgtacc cttagttatt gttaggatta
      301 acacaacatg agacataacc ctaacctata ttttacttta tttatccata atatgtattg
      361 agaaagaatg taaattcgaa tcctttccgt aacccaacta ttgattgttt tttcacctat
      421 tataattagt tattttgaat tccataataa aaaaactgta aaaaaataac gattccctta
      481 acgtacagga agcggttgaa aaatatgtct atacgcacaa ttttcttgtt ttgatatggt
      541 gaacccatcg ccatcaagtt atctaaataa aacaccctct aaaaattaag aatattcaaa
      601 aatgaaaata gacatttatt cacttcgttc gttataattc aaacaaaata aaaaatcgtt
      661 tacattttac gatatcaaat ttactggagg ggataaagat gaaaaaagca ctttacatca
      721 atataggtgg agaaggacac ttaaatccaa cattaggatt agtacatgat ttagtacaac
      781 gtggagacaa cattgtctat tattcatcaa atgattttga agaaaaaatc aaaaaagcag
      841 gtgcacaatt ccgtcccatc aatcaagagg cacaaagaga gctttcggaa actatgaatc
      901 ttatgacttc ccatcctcaa gagtacttat tacacttcct tcatgctatg gaaagaatta
      961 ctgattccat ttttgaagaa atctccaaag aaacatacga ttacatcctc tatgatgcac
     1021 agtctttacc tggaaaatgg gttgctcacc atagaggttt agcatctatt gcaacttgga
     1081 ccacgtttgc tttttcacaa gaactaaaag aaaatatgaa tctgacagga acaagaaaca
     1141 tagaacaaaa acaggaacgt ttagccatgc tacaagcatt tttgcaatta gaagaaatag
     1201 caaaaaggaa acaatattta gaaggaaaat atgaagtatc cctatctgat aattttttac
     1261 tttgtccggg ttcaggcgat ttgaatattg tctttacttc tcgctatttc caaagaaaca
     1321 gcaaggattt taaggctggc tatattttta tcggtccttc cattgctgaa aatgaaactc
     1381 taaatgattt ttcggttgat gaattaaaag gagaacgtgt gatttatatt tctatgggaa
     1441 ccataattaa taatcagcct gaattctatc aaaaatgttt cgtcggttta aaagatctca
     1501 atgcgaaagt agtacttagt ataggcaaac aattaatagt ggagcagcta ggagatatac
     1561 ctgataattt tattgttggt aactatcttc cacaattaga tatactgcgt caagcggatg
     1621 tatttattag tcattgtgga atgaatagca caagtgaatc actttatttt gaagtacctc
     1681 tagttatgct cccatttata aatgatcagc atacgattgc tgagcgagta tacgaacttg
     1741 gcgcaggatt tatgttaaat atccagcaat tatcggccga ggatttaaaa catgccgtta
     1801 atgaagtgtt gcagcattcg atttacaaag agaatgccaa aaaaattagt caatcattcc
     1861 gtgaggcagg tggttatatc aaagctgttg atgagattgt tacatttact cgttaattct
     1921 gctatgtatg ccactcaagg cctattaact taagaatttt ataacaccct acaacaagaa
     1981 tatagaagat agaagaaatg ctggcagtat cccatactca tcaagataag aaattaaata
     2041 ccccattact atcaattctt aagttgatag taatgggggt agcaccacat actcagcaag
     2101 ctaaggtctt gaagtagccc ctaaacaaaa tttttaattt ttctacagta atttatgtga
     2161 attcaactca tttttgagaa caatgcattt ctcaagttta tggcgatgta gcggcccacc
     2221 catttgttca actgattact tcatgatgtt ataaaattag taccgtacat attagacata
     2281 tctaaaattt acggtacttt tgtttactat tggctcgctg atttaactta aagataagta
     2341 tgtggtcctt ttacaatttg aatttctttt taagcttctt atattttctg tacgaacgtc
     2401 taacaatgtt taacataaaa tacggtattt taacagggaa aggcaattta taaatgaaag
     2461 gaaaataaaa ggtgaaatat gccttttcta ggtctctcca cttactatct tcttttgttt
     2521 ttaagaaatc agatacatcg accacatatc cccttccttt ttccatcatc acatttttcc
     2581 cgtgaacatc acaaggagtt aacccttgtt ccctcgcata ctccaaagcc tcattgatat
     2641 caagtattac ctgcttagga attttaatcc ccttatgaat agcatcgtat aaagtaattt
     2701 cttttaaacg tttcaatact atgaaatttt ctcctttata tataagcttt gaataagaag
     2761 gatgatttcc aattcttcgg tatgcttctg actctttttc aattccttct ccttctcgca
     2821 cgtaaacttt cactacccaa tctttgtatt ctctgtgcat gaatactgcg gcataattac
     2881 ctgtccctaa acacttccaa agtctaggaa tatctttaac tactacaggc tcgaattcat
     2941 cttcacttcg tatgcttacc tcttttaata attcgtcctt tattaatccc acaaaactat
     3001 ttatactcat cattcccact ccggttttgc taaaaggggc ccacccacat tttaacgaaa
     3061 atatacacta agcgaatatt agcataaaac gagtcatctt tcttcttaaa ataaaaagat
     3121 gactcgttct atttgaactg ttgaatactt aatatttatt ccgctattca tagccaaaaa
     3181 ctgtacaaca taaaaatatt tctaactatt ttcatttttt cacaggcaac tgtatagggc
     3241 ttttcttagt gcaagttctc ttagttcatt acccatgcca aatctatatt accctatttt
     3301 ataatctaaa acactgttta gaagtgtagc aagatttttt taattgttca aattcttgtt
     3361 ccactaatat ctttgttagc taaaactttt attgttttaa tagccttttg tttaattccc
     3421 acaatgctgt tttgttgcta tcccatttca aaaacgttac tgcttcctcg aagcataacc
     3481 atttataatt gaagtgttct ttagataatg atatgttttt tgtagggact ttaactccaa
     3541 aagaaaattc ttttattaca taaacctctt ctccccaaag gaatcctcca actacatcct
     3601 ctactggtag tgaagacaca gaatctaatt gtatatatgg acattctctt gtaataccag
     3661 cctcttcaaa cgcttcccgt tttgctgatt caataggaat ttcaccgtct tctccgccac
     3721 cagctattcc ttgccaataa ccataatcac ttcggttaaa aataccatat tgaatagaat
     3781 cgtcagtttt tatataagga aatatcaata cttgatatgg tgctctcatt acttaacctc
     3841 ctctcgaaaa taagttttaa atcaatatga ataaagagcc gacatcacaa ttctacatta
     3901 ttaatgcagg tttataatgt cggccctcta tttttaaaga attttatttt tcataaacag
     3961 gcatactctt aacagaggaa aaactgttta ttccttgtca aatttgttta gcatggtttt
     4021 cctaaatgtt agcagtaccc catattattc aattgctcca gcaacgtcat aatcatttaa
     4081 atctaattca atcggttgtc cgagcgctag tttagcaagt tccgctccta agtatggacc
     4141 agctgttaaa cccgaagctc ctaatccatt cgcaacgaga attccttcaa agttaggtag
     4201 cggtccgata acaggtaaga accctggtgt gaatggtctg aatccaactc tcgtttcaag
     4261 cattgtagca ttttctaagc caggtgcaac tgctaatgct ttatggaata cttcatgtag
     4321 accacctgct gttacacgat gatcgaaacc cgtatcattc tcatgtgttg caccaattac
     4381 gacatgacca ttgtcgaacg ttaaaatata ttgatcgttt ggtggcataa caactggcat
     4441 attttctgtt gctgtatttt caatttgcag atgaacaatt tgtccttttt ggaatgtaac
     4501 taagaaatta attcctaatg ggttcaagat ttcattcgcc catgcacctg cagttacaag
     4561 aaccttttct gctaaaattg tttcatcgtt tactataact ccagtaatat gatttccttc
     4621 acggactaat atggcatcgc cttttataaa agttgcacca tgttttttcg cagcacttat
     4681 taatgcattg cgtaataatc ttccatttac tcgtgcagca ccactaatat gaacagaact
     4741 atattcgtct gataatgctg ggaataattt ttttgtttct tcagctgata agcgagtgat
     4801 ttcaccaatc tctggggcat cttcacgtcg tttataagct cgctcttcta tttgatctaa
     4861 ctttttttcg tcagtatgta aactaattgc acctacacga ttatatcctg tgtcagtttc
     4921 accgtcttct tctaattgct gaattaacga agaatagtaa cgtgcaccgc ctttaacgat
     4981 tttataccat gctttattac gacgctgtga tagccatgga catacaatac ctgctcctgc
     5041 atcagttgct tgccctaatt gttggcgatc cacgatagta acattcgcac ctgctttagc
     5101 aagatgataa gcagtagacg ctcctaaaat tccagatcca actacaatat acgatttcat
     5161 ttcaaacacc ttttctcttt ttgctaatta tataaatata agaacattcc ttagtataat
     5221 ggaaagaata cttttttcaa tgtactcatc acaattaatt gttgcagcat tgtgactttc
     5281 ttagtcatta ttttttcttc ttacggaata attcaattgt tttatagcct tgtgaaagga
     5341 tttctatcat tttctctaga cgtttttcac gtgttttttc ttgtttcaca gaaaaaagat
     5401 tacgtgccca atctttttgg tatccaggcg ttaaactttg ataaaactta agttcattcg
     5461 gatgattagc taataatgct tcaacatctt taattcgatc tgcataatcg gcaacacatt
     5521 gactcatagc agatgttttc attgtttttt tcttttcacg ttttaaacct acaacagtaa
     5581 agacttcatc catacttacc attcgtgcaa atttaatatt gctttctccc acataaccat
     5641 cttctccaac gtttaatgcc ggaaacatct catcacggtg aataaacgta ctataacgag
     5701 cattaccttt tttcggatat gcgaagaaca cgtaaccttt ttcaattagt aattcttcat
     5761 tactaataat aaaattcgtt tgtttcacca tttcatcaag cgtttctaca aatataaaga
     5821 tagcatcgtg ttcttttgag aatacagttt ctttacctgt aaaaatgtca taattacttg
     5881 gttcgttaat tacgaccata tttgtatact tattaagttt caatttatca ataactgaca
     5941 taataatctt cctttacatt caaaattcat tgtacatact ttttcgtact gttctagtgt
     6001 attatatgta ttaagaaaat caaactttaa atcatattat tctgctgcaa aagaaccagt
     6061 ttttcataca tatgaagaaa ctgaggaaac attaactata ccgcagtttc cgaaacatat
     6121 tagacgaaaa ccatttacac caaaaaataa taaagatagc cgcctctgat taagtaccgg
     6181 ctatctttat tattcattac ttaatagcaa ataaagtata taaaagctct ctatattgct
     6241 cttctgtaac ctcacgctta gtttttgctc cataaataat ttcagttaca ctattattcg
     6301 ttaaagagac atgcccagag tccgtcaatt tcactgcaat tggtccctta ttaaaaatag
     6361 atttctcatc ttctattact cttctttgaa catcgtttac tactatctca tcaataatat
     6421 gtttataaaa ggcatgacaa actttccatt ctccttcagc atctattctt tctaaaacat
     6481 aatttccttt actcgtatct tttcgtctca cccggtacga accattcttt gaagaaacag
     6541 actcatcagt aaaaggtaca ggaacaagag gtactaatga agctatacct acatcaatta
     6601 aatactgtac attagcataa gttaaaataa ttgttatatg gccatcctca agtgcccatg
     6661 catttatatc atttttataa accgtaccta atgccagttg tacatcatag ccacagtctt
     6721 ttaagaaata gtaaaaaagg gtgtttaatt cgtagcaaag tccaccacgg gaactagtta
     6781 aaattttctc tcgtaagttt tccagagaga tttgattcgt atttcgtgct ataacgtcta
     6841 aattctcaaa tggtatagta tgtgcaaatg aaaagagtat agtaggtaat tcttcaaacg
     6901 ttacttcatt acgtttttta agatttaatc ttgcgaaaag ctgatcttgt aaacttgtca
     6961 tatttagcac cccttaaaat tttataagtt taaataatat atgctgattg taagttttaa
     7021 ggggtactgt aacaacgtac attttatgta actgtaccgg tacaaaaagt ctaaccgaca
     7081 agatcactaa agataagaag ctacaaatac aaatttaata gtttgtctat aggtaaatta
     7141 ttacaatcgc ttaaatcaac aaaatactga agttgccaca tttggctctt tttagcttga
     7201 ttgctgacag gcttatccca tataggataa atcctcatag ccatcttgcc tttttgattt
     7261 tgtgttctca agattttttc cttaagaaga atctctttag gcaaaatgaa ttgtcctagt
     7321 ttatgatcat ctatacaagt aataactaat aagtcaggag cagcgtcata agaaaatgct
     7381 tgattttgca tattgtcatc tttctcccaa aaagaaacaa attgcccaat tttattagga
     7441 gtaacttttg attttctaaa acgaatggtt ttgttattta agtggaataa acatcctgca
     7501 tattctgcgt tttgcttttc ttcttttaga ttcgtaatca ttaaattgtt aggttggtaa
     7561 actatattat ttaaatttcg gatcgtatca ttaaaattgt tcaaaaaaac tcccccttta
     7621 ttcatctctt agtttaccac aaacatcagt tcttctatat cgtatataat catgaactaa
     7681 gtgaaatggg ggaatttagc aggatataat ttttacttta atgtacttag tttttcaatt
     7741 gcttgttgct cagttgctaa gtaaaaaatg tcattccctt tattacattc ataaataaag
     7801 tcttttaagc ttttactagt gtaaatagag aactccccaa tgatagcaat ctttaccttg
     7861 tagtttataa acttttgaag gatatcaccc gcaagacgtg tttttaaatc aaagaagctt
     7921 tcacttatta atgacttgtg gataataata tgcttcgcat ctacctcgta ttgaactgtt
     7981 gccatagtat ctaatgcaga ctgaacatcc gatattaata ccttatcgtt tctaatgacc
     8041 gcaatattga ttccatcgat tactactttc tttatgtcca tagtcccacc cctttataat
     8101 gtgcaccgta tgagtaaaat tgttttacaa aacttcgtat taatcataga ttaaattagc
     8161 cgcagctatt aaaattgcct ctattcttta ttactaatac ggtcaatgaa attaatgata
     8221 gtttctcttt tttatatttt tgaatatata tatgaaatta cttttacttg ttataaaaat
     8281 attgtggagt aacataactt aacaaactat ccaaagtgtt aatctcggca tatggttgta
     8341 ttttggtagt attcttgatt ttttgagggt taaaccacac accttttata tttacatttt
     8401 gaggaccagc aatatccttt tctaagtcat ccccaacaaa taaagtattt tccggctgta
     8461 aatttagctt atttaatgct agttcgaata tacgtttatc aggtttacta aatcccactt
     8521 cttcagaaat aatgattgtt tcaaaatacc tatttaaatt cgtgttaaat attttagctt
     8581 tttgcctctg agttgagcca tttgttataa ttccaacttt aaagtgcttc tttatttgat
     8641 ttaagaaatg aatagtattt tggtctattg aaaaacatct agggaaatta ttattccaaa
     8701 aatcttggat ataattgcgt ggcaatctat acttcggcgt gaattcatca aacaatgatt
     8761 ctaaaactgt cgttttatta cttatgccat attctctttt atcgtattct ttgaatttct
     8821 gtaacatgtt gcttttagcc gcaccatcta cattttcata acacttttct aaaacaatta
     8881 aaaataatgc cgctactgcc ttatccctat caagtaacgt atcatctaaa tcaaacagca
     8941 tacctttata acacttcaaa tcatttcaca acctttctag tattatgtaa acctcttcaa
     9001 gttcgtaccc ttaaactttt ggtttagcaa gagcattgtt atgtagtgat taacgactaa
     9061 acagaaacta gatgaaagaa atccaaagtt cttggcacac actctagtat tattgtagct
     9121 tcttctatat taaaattcct ttccctcttt tggtaaagaa gcacaagtat attttcacaa
     9181 actttaagaa attacataca attcacatta ttatacatta gtttttcgta aatattattc
     9241 atacatcaat tcatacgata agttttttaa tcaattattt ctccataaaa aagtaatata
     9301 gctaataata ctttttggta gtaaacgtcc tatgaagttt actactgtat ctccacataa
     9361 actccagata gtacggctat aatgactacc agaggtgata ttatgaaaaa ctatcatatt
     9421 ctcgtggtag aggacgatca agaaattcag gaattaatta aacaattttt aatgacacag
     9481 cattatacag tggtagtcgc ttcagatgga ctagagggta tgacacaatt taataagcaa
     9541 tcctttgatt taattctcct agatgtcatg atgcccaatc ttaatgggtt tgaagtttct
     9601 aaaatgattc gaagtcagtc aaacgtacca attattatgc taactgcgtt ggaagaagag
     9661 gaagatcaaa tgaaaggatt cgatcttggg atcgatgatt atataacaaa acccttttca
     9721 tttcatgttt tgattagacg agtcgaagct gtacttagaa gaagttatga taaaaatgta
     9781 aataatcatt tgatatttaa agaagttcgt atcgatgtgg atgcatatag agtctatgta
     9841 aatgatgttg aaattatatt aacgacaaaa gagtttgaaa ttctacaact actatttcaa
     9901 aatgagagaa aagtacttac aagagaaaat atcgtagaga aggtttgggg gtacgattat
     9961 tttggagaaa cacgaataat tgatacacat attaaaaacc tacgcaaaaa attagctatc
    10021 ccttatatta aaacaataaa gggtattggt tataaaattg atgaatagta ttgtgaaact
    10081 catgaagatg aagcaaatta cttataaact ctttatgact acatctctca ttttgttatc
    10141 ctttgcagta ttgatttatt taactttata cttctttctc cctacgtttt atgagcaata
    10201 taaaacagat caacttcaaa cagggataaa cgaaatcatt gataagtcta aaaatcttac
    10261 gtttcaagat gcgataccac tttttgatga atacgcaaaa aaaaataatg cgatgcttta
    10321 ccttcaaaat aaagaaggag taattattta ctctccttca ttttctttta ttcaaagtgg
    10381 tacgcaaaaa acagtagtta ctaaagcaac acgattcgag aatgcaagta cccttagcaa
    10441 ttcatataac gttacgaaac caattcaatt ccaagatggt agtttaacgc ttatagtctt
    10501 tgctacattt caaccgattg atgaagcttc acaggtttta gtacgatttc tcccctatat
    10561 tagtatcatt gtgctcatta ttggtatagg aagtgcttat ttttattcca ggtttattac
    10621 aaagccactt atttatatta atgaaggtgc acaaaagatg gcaaatttag atttctccga
    10681 aaaaattgag gttcgctcta cagatgagtt aggagaattg tctaatagtt tgaatgacat
    10741 gtctattaac ttacaacaag ctatgtttga tttaaaaaaa gcaaatgaac aattaaaaaa
    10801 tgatattgaa aaagaaagag aaatagaaac aaaacgcaga gagttttttg cgattgtagc
    10861 acatgaatta aagtcccctc ttactgtaat gaaaggatac ttagaaggga tgatatacaa
    10921 tattggccct tatcaaaatc gcgatcaata tttaaagaaa aatcatcaaa ttattgaaag
    10981 tatggaacaa ttagttcgtg aaattttaag cgtatcgaaa ttagaacaac acaccttcaa
    11041 actaaaagta gaggaagtta atccttcaaa gttaataggt acaatcacaa aagatctcga
    11101 attttttgct tctcaaaaaa gtatcgaaat aataaaagaa tttgattctg acctttctat
    11161 ttatacagat tgtgctcttt tagaaaaagc atgcaaaaat attatccaca atgcggttat
    11221 gtattcacca cataatgaaa aagtctatat aaagttaaga gagaattcta aacaagatca
    11281 aatcgaaatg aaaattataa atacaggtat caatattaaa gatgaagata ttcaacaaat
    11341 tttcaaacca ttttatcgaa ttgaaaaatc aaggaatcga aatactggag gaagtggttt
    11401 ggggctatat attgttaaac aaattcttga aacgttagat ataaagtatt caataaaaaa
    11461 tatggaacat agtgtgcaat tttgcatgag tattccgcta tctaaacata aaaacaaata
    11521 aactctcctt taaataggac gagtttattt gtttttgtag taagtataaa cttattaaca
    11581 ggcttttcgt ttaatgacgt atgctacttt ttaaatggcg attgtcataa gtagtgacaa
    11641 actgtattca acttaaatgt ttacctataa cagcaaaaaa agcgaaatta cgcttagcag
    11701 caaattagat tctcttattt gagatacatt tcatctatga aactgaaaag gaggatgaaa
    11761 aatgtttatt cacctccatt tttcagatta atttggaatt cttttatgat aagctatatg
    11821 taaagattaa acataaagga tgattcgtat ggaaataaga ccaaaggtaa gtgaatataa
    11881 ctcctattat gcaacgtata ccaacttggt atcagacgga aatatcatac atattctaga
    11941 acaacaaatg aaggaaacga atcttttatt aaagggaatt tctaatagta agggactttt
    12001 ccggtatgct cctactaaat ggagtataaa agaagtaatc ggtcatatag cagatacaga
    12061 acgtattatg gcgtatcgat tgctatctat cgctcgaggc gagacagcag aacttccagg
    12121 ctataatgat gatatgtatg ttcttagagc tgcttttgat aagcaatcta tgcaagatct
    12181 tcttgagaat ttaatagttg ttcgccaatc taccctgtat ttacttagaa gcttagataa
    12241 agaagcctgg tcacaaagag gaaatgcgaa taattctgaa gttacagttc gtgcattagc
    12301 atacatcatt gccggtcatg agcttcatca tcttcaaatt ataaaagaac gttatcttgg
    12361 ttctgatgca tatccagcaa gttaatattt gaagaacaag agtcctattt atgtagggct
    12421 cttgttcagt atttataacg tattagcact tagaatcatg gcaattaaat gcatttattt
    12481 ataaaattca ccacataata tatatgctat cctcttttat tctgtacata attttcttta
    12541 ggttgatata ctataaacac aatagttctg gaaaggtgat gatattatgt atgaacaaca
    12601 aaataataga gatagagatc aaaaaatgat gttttcgatg caaggagttc ccacaaataa
    12661 aattaacatg aatcaattac ctaaatggat taaaattttt ggatattgtg cgtttggttg
    12721 gatgatagta tttagtttaa ttatgattgt aggtttaatt ctgcaataac tatacagata
    12781 catagatagg taaacgggac gatatttaga ttatacatct aggtaatgtt ccgtttttta
    12841 tgtatgatta tcccatgata taggtaacca attatactaa aaagaacttg tagaatatcc
    12901 tacaagttct ttttcaaata ttattaaaac gggaacaaca aactatttta acattcagta
    12961 cagggagacc attttgatta tggcttgatt ttattataaa acaaatataa gcttttgaaa
    13021 ggtctagatt ttgaaaatta tgtgaattga acagctacga tgtttatatt agatttcatt
    13081 tacaaccaac ttcttcttac ttaaatacac tgcacgatct gattttttag caacctcctg
    13141 tgagtgcgtc acaacaataa tacatttatt ctctttatgt gcaagttctt gaaacagttc
    13201 tataatatcc attgcggttt cctcatcaag gtttcctgtt ggctcatccg caatcaataa
    13261 atcaacatta caagatagtg ctcgagcaat tgctacacgc tgttgttgcc caccgcttag
    13321 ttgcaggacg tttcgtttcg cttcagcttc tgagagtcct accctctcta ataactgtaa
    13381 tgctcttgct gttttatttt gcactttaac acctgtaatt tccattgctg ttaagacatt
    13441 ttgaagagct gtcatatagg ttattaagtt ataagattgg aaaattacag atacattttg
    13501 attacggtat cgatccaaac caatttttct aatatctttg ccattataca gtacataacc
    13561 atttttaggg acatctagtc cacaacctaa gcttagagtt gtggttttac cagatccaga
    13621 tggtcctaaa atcgtgtaga aatgtccttt ttgaaaagaa aagttaacat tttctagtat
    13681 cgctacattt tttccattac tttcataata ataatccaaa tttttaaact gtaaaattgt
    13741 ctccatatcg agcctcctca ttcatctttt aaaagaattt gttttgggtt taaacgtaga
    13801 atagataatg ccggaagaag cgttgctatt atagcaatag ctagtccaat tccacccatt
    13861 tttcctacat cttctcctgt tacacttaca tcaattttat taatcggatc ttctttttga
    13921 ttttgtagag taccaccagg tccagccatc attacagtac catgttgcga ggtatctgtt
    13981 tcttcgcttg aagtagcaat ttcattcgaa agtaaattat ccccgatata ttgagaaact
    14041 ttagctcctg ttgttaggga taatccaaat gctaaaatag cgacacacac tacttctact
    14101 acgaattgcg ccatcagctt ccactttttc tctccaatgg acaatagaat tcccatttct
    14161 ttacgacgcc ctttaattga tagcattatg attaatccta aaatgatcgc acctgcaatc
    14221 gatacaatat aaataatcat ttgagaagtc gaagagatat tttcgatagg accaatcatt
    14281 tgcttgtaca atgaatcatg cgcatctaat ttataataat taaaatcaat attaaatttt
    14341 cttgcttctt ttttaaatgc atcaatatat tgtggatcat tcaagaaata cacgacttga
    14401 acactactta taccttggtc tacttctaat tttttcatag ttgaatgcgg catatatagt
    14461 ttattagctg gatccataat aggaggagcc tgttgaccca ttgcttgctc atttgtttcg
    14521 taaataccga taatttcaac ctcaagggtt tccttcttat cccctgattg cactttaact
    14581 ttgtctccta ctttcaaatt gtttaattcc gctaatcgtt tttccattaa agctacattc
    14641 tgatccttca tttgctctgt tattggtttt ccatcaatga ttttactttt tccgttttta
    14701 aagctttctt gtaatgcagt cttgcgaact ccctcaatca taaaagaagc gttcatatcg
    14761 atttctgtac cagagcttga accgcctcgc gcagccgcca ttcccacttt accttttcct
    14821 tcttcttctg aagctcctac tagtttaagc ccatcagaaa taccgaaagt gttagctatg
    14881 taattataat cttttacata cttggacttc gctaattgat ctgtttcttt tgcatcgagc
    14941 tgcggcggat ttggcatttc tccagtttcc ttagcttttt gacctaattt gtcgaaatca
    15001 agacctaaag taacatctgc accaagtttt tttcttgcag catccgctgc tttttttgat
    15061 gcattttgga ttgtgaaacc tgaaagaacc aaatttgtaa caatcagaaa aactgccatc
    15121 aaaattaatg atgttcctat cctttttttc atactgagaa ttgctcgttt cataaaattc
    15181 attttttctt acctccttga taacttgtat tctatatagg ttatctagag tttatatgga
    15241 gctaatcggt agtttaacta gagatataag gagtttatgt gtagttattc atttacctgt
    15301 tcaagaaaag ctagaacaca aattcaaaaa tacagtcgtt tttgaatatt ggtaaggagt
    15361 tattccgttt aataaattta tataagatta agattaattt aatgtatgta gcacaaaaaa
    15421 tatttactgt gtaatttcta tacaataaat atagagaaac ctatttggat atctataata
    15481 gggattttaa tatagttact gtatctcata caaatcacgt cgctttaaaa ggtgcatctt
    15541 ttaatacgaa aataagcaag ttaatattct cttatatgaa taagaatatt aacttgcttt
    15601 ttagatttta gtataattta tttatagttt tattttattg caaactttat aatatgatat
    15661 ataaatttat cacctactat taggaaaaga gaatatttta taattaattt acaacataaa
    15721 ttttgtccat gttttaaaca atatgtattt tggaggaggt taatttgatt ttttcaaaac
    15781 tcattgatcg gtacgcctta tatgatttac ataaaaaaag aagtgtagca tttcagttta
    15841 cttccctttc taacacttca ttaaatataa agaacataga atctttttat aaagtacaac
    15901 catcacattt tcattttgac attaagcatt caaagcagga aaatgaatac atggttgggc
    15961 aattcaacta taaaagttcg gttcaatccg gtgattcacg caacgactct gtaactgggg
    16021 aattattctt acataaaaat gaaaatgcac ctcatgttat ctttgttcac ggttggagaa
    16081 tggattctaa cgaacgtgtg aaaaaatatt ccactatcat atgaccagcc tgaagtggaa
    16141 tatgtattat ttcactctac cctatcattt tgaaagaaaa cccgatcaat ccttattcag
    16201 tggagagtat atggtaagtg caaatattga acgaacatta caagcaacta gacaagcggt
    16261 agctgattta cgagctttga ttaaatggat taaagcaaat aaaaatgggc ccctgattct
    16321 aataggaatt agtttaggcg gatttattac taacttaacc tctcttgttg aagaagaaat
    16381 tgatgtgtta gcatccattt tctatgcaaa tcgactttct tattctattt ggaatacaac
    16441 tccaggtaaa tttattagag aagacttgga acatcatggt gttacgtatg atgatttaat
    16501 agattattgg aaaatcactg aaccgagtca agcattgcca aaagtaaaaa aagaaaatat
    16561 tttattaatt tcaggtaagc atgatctata tgtgcattct gaggatacag attacttgtg
    16621 ggaatcttgg gaaagacctc cacgatatat ttataaatgt gggcatgccg ggatcgttct
    16681 taaacgtaaa aaaattgcaa ctgatactat tgattttatt caaaatcgat tgaactcccc
    16741 gcacttatcc aatgtcatgc cttaaatcgc gagattacta agtacaaaat cttatactta
    16801 tattgttata ttttttacta gtcacctttg taaatcttcg cccctagcct tacacgattg
    16861 aaaatgaaat aaaataaata actaaggaac taatttacca tatggaaaaa cattgctcaa
    16921 cattttcact agtagtccct gtatatgcaa tattacatat aaaaatcttt atgtattccg
    16981 ttattaattt aaaaggaaat tattcatcca ttaatctata ccatccgtat ttgcagttaa
    17041 ggatacccta attacatatg aaaaagagag aagaacattg gttagttctt ctctctttgt
    17101 ttatttttaa gataactatc tataaaattt tgcttttcat aattcttcat gagtctagaa
    17161 aagaatctaa tccttttcta gactcaaaaa gaaatttttc taatgtacat aattacaacg
    17221 acattaaacc actttgctct taaatccaat acttgtatta ttaattgcat gaaagtcctt
    17281 cttgagaaag gttttaattc ctgaatattc tgttgaccgt tataacatat ccaatttaca
    17341 atttaattgt ggtgttcttt cacaattaaa ctacttagaa tacacttcat ttatttgaaa
    17401 acaattacaa atagaggtgc taaaatgaaa actagagtaa atccagaatt attacaaggg
    17461 ttagagatgt ttccggatct cgatttacgc ccggaaaact tgcaatcaat cagagaaggg
    17521 atagctcaaa tgagaccacc taccgttgtt gatgactccc tttcgttaac agataaagtc
    17581 attgttggac ctgatgataa tccgttacca ttaagaattt atcgtccaaa atcaaatcat
    17641 gaatctttac ctgtcttatt atggatacat ggtggtggtt atatcttagg ttctatagat
    17701 gataacgatg atacttgtat gaggtttgca aaagaagctg gctgtgtggt tgtatctgta
    17761 gactaccgct tggcacctga acacccttac ccagcaccaa ttgaggattg ttattcagct
    17821 ttaaaatgga ttgctgataa tgcaaagtca ttaaacattg attcaaatcg tattggggtt
    17881 gcaggagtaa gtgccggcgg tggactaaca gcagcattat cattattagc ccgagatcga
    17941 aaatatcctt caatttgttt acaaatgcca ctatatccaa tgattgatga cagaaatgat
    18001 acaccttcag cgaatgaaat taaagaggga tttgtttgga atcaaaaggc aaatgaagct
    18061 ggctggaaaa tgtatttagg agaaatgtat ggaacggatc aaatccctgc ctatgcagca
    18121 ccttctcgag ctgaggatta tagtgactta ccgtatactt acacatttgt tggtcaatta
    18181 gatccattcc gcagcgaaac attaacctat gtaagcaaac tagcgcaagc tggtgttgat
    18241 gtggagtttc atttatatcc aaatgcctat cactggtttg aagggttaaa tccaaatgcc
    18301 gatgtatcta tttatgctgt gaacgaaata gtacaagcaa taaagactgg tttcaaacga
    18361 gtatccaagg ttgaggctta atcccattac aagataaata cttataaata gtatatatgt
    18421 tatcatttaa acataatagc cgattctaaa tgagaatcgg ctattaatat gtaaaatccg
    18481 cctaatatat caaggttgag aaacagatat aagatgttta ggcgatgtgt tttatttcct
    18541 ctgccaatgc ttttatgttc atcatgattt gaagtatttc ttcttttgtt gtccttgggt
    18601 tgatagagca aagtcgaatt actacttttt cttttaattt agtagtactt agcatagcaa
    18661 atcctctttg attaatttct tccaccaatt ttttgtttat ttcatgaatt gtatctgtag
    18721 atgttagctc acatggaata taacgaaaag taacaattcc taattgggcg ggtgttacta
    18781 cttcccaatc tttttctttc cttaaaaact cttcaacttg ttcagctagc ataatgccat
    18841 gatcaattgc ctcacgaaaa gctgtaactc cgaatgcttt aaaagaaagc cataccttta
    18901 atgctctaaa tctacgagaa agttcaattc cacgctcccc aaaattcact ttttcttcta
    18961 tattagtttc tgtatcctta atatactctg ggatcatacg gaatgtttca cttaaatatt
    19021 ggctatttcg aatgagtaca caaccaacat cataaggctg aaaaagccat ttgtgcgggt
    19081 ctaacgttaa agaatcggca cgatgaattc cacttaataa ctcccttcct ttttcactga
    19141 gaattgctgc agccccataa gctccatcca cgtgtagcca tatatcttca tcattacaaa
    19201 gatcagccaa ttcgttgagg gaatcaaccg ctccgcaatt cgttgtccct gcattagcaa
    19261 taacacagaa tggttttttc ccttttagtc gatcttcttt tatttgcttt cttaaagtac
    19321 taactgaaat ttttaaatct tcatctgtcc caattcggca aatttgatgc tgtttaaaac
    19381 ctaatacttt aagtgctcga tctacagaaa aatgagtttg gttagaaaaa taaacaatcg
    19441 ccttttctac gtcattattc agcttgacct gtctcgctac agtaagtgca gtcaaattag
    19501 ccatggaacc gccactgaca aataggccct cagctgaatc agggaatcct agcattgatt
    19561 ttaaccagtt aattgtcgtt aattcaattt gttcagcacc tgcacctact atccaagctg
    19621 taggaaatac attaaaccca cttgctaaaa aatctgctaa tacaccaaca taattgttag
    19681 gacctggcac aaaagccata aaatgaggat gatccacatg agtaatttga ttaaacacat
    19741 tgttattaag aaaatgaagt aattcttttg gattagatcc gttttccgga atcgtttcaa
    19801 ttagcttgtc tctaaaaata ttactatcaa tcgtttctga aactggttta ctttttaaat
    19861 gattcatatg atcaacaatc aagtcaaccg cttgatatcc taactgacgc atctcttcgg
    19921 ctgatagctg caagtttttt gtcatttgat ttacccctat tctatttaaa aaggcgagtt
    19981 cttgctcgcc ttttcatttt ttataatttg taatcacaaa ttgtttgtat tggattttga
    20041 agaatcgtgt tgattaagca atggatgtga tttaatattt cctgtatttt cttcgcttca
    20101 tataaagttt gatcatatcc aaactttatt gtaagttttt cttcagggaa gcacataatt
    20161 ccatacttta catgtggctc atcaacaact tcgtaatccg tgatagcaaa atgtctgttt
    20221 tcatttgaag aaaagattgc tggattagtt ggatagtttt caaaaaccca aagatggtca
    20281 gtcaactcag tttttaattc actttgcttt tgtatatcaa caaatgaata gtatgcatac
    20341 tcattacatt tcaatgtctc tagttgtact ttttgcagga agtccacaaa agactgcgtt
    20401 tctgtccatg ctaatcggat aggcaaaaca tttgtgaaca gaccgaacat actttcaatt
    20461 ccttctactt cgggaggtct gactgatacg agattaggca atactacttc tctcgttccg
    20521 ttgaatttgc caagtaatat tccccataca gctagtagtg ctgtattcat agttatattg
    20581 tttttagtta caaatgtctg taactgatta gtcaaatcct tgtctaatgt taaatccata
    20641 aaagtgaagt ttaacccttc acttttagat gggactttct ttttaggaat actaattttc
    20701 tgattgtatc ctgataaata atccctccaa aaatgacgtg ctttctcatg atcttgtacc
    20761 aaagtccagt ctatgaatgt ttcaaaaggt tttactatag gtaaccccgc cgtagttccc
    20821 gcatttgttg tttcatagag ctggaataat tcgtctatca aaatgctgac gctccaacca
    20881 tcacataata gatgatggga actccaaatt accttatgct cgttattacc tagttggaat
    20941 atacagagac gtgtcataag ttcatcattt ttaaatcctc gacttaaatt ttcattcatc
    21001 cactgtttta ggaattcttg ctgttcttgt ttcgtcatct caatcaagtt ttttatttct
    21061 gaatttattt gaacatcata tagaacagct tgccaaggtt ttgcttgttc atcttgcaca
    21121 attattgttc ttaaagaatc atgacgatca actaattgtt ggaaacactg aataaagagt
    21181 ttaatatcca actccccctc aagtgcccaa attgtttgtt caaaatatgc atttgtatca
    21241 ggttcattcg tagcatgttc ataaataact tcttggaaag gtgctaacgg gtaaatacgt
    21301 tctattttta tatccggcat tttttcttgt attttggtaa gtgtttgttg attaagttgt
    21361 ttatctttaa tatttagtaa tgtagcttta ttatcgttca ttatgtttac atcatttgtt
    21421 tgtgaacttg aaaaatggtc tagcttttta acaaattgaa ccatgtccct taatatagga
    21481 aatgaaaata gattttttgg ttcaagctca aatccttgtc gatacagtct gacggacact
    21541 tgaatcgctc ttatcgaatc tccacctaag gcgaagaaat gatcatttac tccaacttga
    21601 tctattttga gtacttcttg ccaaatacta gttaatattt tttccatttc agtttttgga
    21661 gcaataaata cttcatttgt ttgtttctcg ggagtaggga gcgcttttct atctaattta
    21721 ccgtttggag tcaagggtaa ttgatccaaa taaacaaaat aagaaggaat catgtaatct
    21781 ggcaagtgat ctcgcaaatg ctttcgtagt tctgttgtac taatattttg ctcagttacc
    21841 acatatgcaa ctaaaaattt tattccgttc tcatctgttt gatcaattac gacagcatgt
    21901 tcgacttgtt tataagttag aagacaatga gcgatttctt ctaactctac tcgataccct
    21961 tgaattttta cttggtaatc ttggcggcct aaaaattcaa tatatccctc agaatgcatt
    22021 tttccacaat ctcctgtttt gtatataaga ccaaaatcag gatgtgacac aaacgcttca
    22081 tttgttttct tttcatcatt taaatatcct ttagcaaggc ccactccccc gatatataaa
    22141 tctccagtta caccaacagg gcacattttc ttttcatagt tcaacacata atacgtttgg
    22201 tttgccaagg gcatcccgta tggaatacta ttccaatgtg attccacctg tttgaccgga
    22261 taataaattg accaaatcga tgcttctgtt gcccctccta gtgaaactac ttctgcaatc
    22321 ggaaaatgtc gttttatttt ttctggtaaa gaaagcggaa tccaatctcc actatgtaaa
    22381 actaaacgta aagaagaatg ttcaaaatga gaacctactt gatccaatgc caaatccatg
    22441 attgcaggca ctgtattcca aattgtaatc cctctacgtt cgacagtgcg gattaattct
    22501 tgcatgtctc tcggatcacg aatcattact aacattgcac ctgtgcttaa agctccgaaa
    22561 atatcgtata cagataggtc aaaacacatg gaagagatac caataatacg atcatcttca
    22621 tttacctcat atttttgatt tatgtcttga atcgtatttg taaccgcttg gtgagtaata
    22681 attactcctt ttggttttcc tgtacttcct gaagtgtata taatataggc aatatcttct
    22741 ggaccagcaa tagcgggcat gtcttctgtt gtataaaatg acaaatcatt ttcttcataa
    22801 agactaggtt ctaataaaag cttgcatgag ctatttttta aaatatatgt ttggcgatct
    22861 aaaggatgat cgggatcaat cggaacatag gcagcaccta cttttaaaat acctagcata
    22921 ttaacaattg tgtcaactcg tcttttggct aaaagaccca ctttgtcacc aagaccaatg
    22981 ccctgctctt ttaagaagtg ggcaatttga ttggagcgtt tatgaagttc cgagtatgtt
    23041 aaccattttt gctcaaatac caccgctact tcattcggtg tacgttttac ttggtctgta
    23101 aataattgat acagagtagt tgaaggtatt ttttctgttg tttcattata ttgttcaatt
    23161 aaagtttgat ccgattcttt catctgcaaa gatgttatat cgctttgttt caccaattgt
    23221 tccaataagt caacaaattg ggaaaacatt gcttctatca catcaatatc aaacaactct
    23281 tcaacataat tccagctaat taataactca ccattttttt caattactac attatccaaa
    23341 tacacttgtg gagtccgagc atgaatatag cgaagagaac caagttgttc ccaagagaaa
    23401 gcacctgcac ctgctaacat cgaggtgaaa acgattggca taactgcttt tggcgtcatt
    23461 tgatgatatc gagtaaaatc tcgaataaag ttaactccat cgtaatgacg atgttcaagg
    23521 ccatctaata aagtagattg cgtttctttt actctagtaa agaaagtttg ctctggtttt
    23581 acatcaacat ccaacaaaat aagcgatgtg aaatctccta caatctgttc tacttcatca
    23641 tgaacaggat aacggttaaa tacagtcaaa ttaattgcta atcgacgttg attactccaa
    23701 tatgccaaca catcaccata tattgtacaa agtagagcgg aaggcgttac ctctttctct
    23761 tgtgctaact ttcgtagctt tgtccatttt tcattgtcca ggatttttgt aagtgattgg
    23821 aatttaggag tagcaatctc tgctggatcc ttttttaaca gcaaagaagg tgcaaacgga
    23881 aagtcaggaa gcttacttgt ccaataatct tttgctgttt tatattctcc gatttgtttc
    23941 atttcatcat agataaacat ataatcttga aaatcaaaag ataaagattc taatctttga
    24001 tttggtttat aataataatg caacaaatcc tgtccaacaa tgttcatgct tgctccgtcc
    24061 attaataaag catcgtatcg aaaacataat aaatacgtgt cttcttttaa aagaaaagct
    24121 ttcaattcaa acaaaggcca ttgccccaaa gggaatacat ggttagtcat tcgagaacgc
    24181 tcttcttgca agcgagcatt ttgattccta tcatctaaat ctatgagact cactatttca
    24241 atctggtaat caggaacgct ttgtaatatt tgctgttttc cctctggtaa aattacagct
    24301 cgcaacattg gatgacgatg gattaccttt tgaaaacttt ttgaaagacg attgatatcc
    24361 aatgttgttt catattcaaa atatgtttga ggtgaaatac cacttaattc aaactgtgaa
    24421 ttccttccta acatatacgc tgtctgaact tctgttaagg aaaatggatt agataaatct
    24481 ttaacatgag ttggtctact ttcaaagttt tcctctttat gctctaactt tacacaagaa
    24541 ctcagttgag cgattgtagg gtgcttaaaa aaatctgttg tacttatttt taagcagtct
    24601 tttcttagta aattaattac ttgaagtgct ttaatggatt ctccttttaa tgcaaaaaaa
    24661 ttatcatgaa taccgattcc ctcaatctcc ataacttttt cccatgcaca cactaatttt
    24721 tgttcaattt cattgcgcgg ggcaacgtat gggattgata cataatccgt ttgtgttata
    24781 tccaataacc tttttctatc cacttttcca tttggattca atggaatctc ttctacctga
    24841 atcatttttt caggaatcat aaactcaggt aatttatcac ttaaatattt tctgatttca
    24901 ccaaaagaca ccttgttatc cgatacatag taggcagcta ataatttcct atttccatac
    24961 acttgatcaa caacgatagc ctggtttatt tctggatatt cccttaattg agtttcgatt
    25021 tctcttaatt caatccgata cccccgaatt ttcacttgat gatccattcg acctaaatac
    25081 tcaagttctc cattaggcaa ccaacgaacg agatcacctg tatgatacat catttctcct
    25141 gccgtaaaag gactcggtac aaatttttca tctgtcagtt tacttttacc aagataccct
    25201 cgtgctactg ctactccagc aatgcagagt tcaccgggaa ttccaaatgg ttttaattgg
    25261 ccatacttat tcaatatata ggaatgataa ttcggatttg gtttaccgat cgtaacttct
    25321 ttggaagtgc tcaagtcttt tactgttgag caaatggttg tttctgtggg accataaata
    25381 tttaaaattg ttgcttcact gatacaacga attttttcaa ccaaatcaat agaaaatgct
    25441 tctcctgcta ataaaataga ttttaaatct tttagaaaat ttgccccttc tggatcactc
    25501 aaaatcactt ccattcgcga tggcgttgat tcccataaat ccaccttatg ttttttgacc
    25561 aaatgagcca attcttttgt tgcaaactgg tcctctgtag caattactac ttttgaacct
    25621 tgcgttaaag gaagacatat ttctaacaag gaaatatcaa aagatacact agcaagaaac
    25681 aagaatgatt gattagcctt tactttttct ctcattacat ttaaaaaatg aactagcgat
    25741 ttttgttcta tcattacccc ttttggattt cctgtcgatc ctgatgtgta aataacataa
    25801 gccaaatcat taggattatg ttctcgtact aaattacttt cttcaccttg aaaaagatat
    25861 tctttatcaa gatacagtac ttcacccgca aattgtggca atacttcctc tgttcgctta
    25921 ctaagtaaat attttgcttg actatcttgt aacatatatt caattcgttc agttgggtag
    25981 ttagggtcta ttggtaaata ggctgctcct gcttttaaaa tccccatcat accaataatc
    26041 atttctaatg accgatctac cataacgcca ataatacttt cttttgaaac acctttactt
    26101 tgaaggatgg aagccaattg attcgctttc ttattcaatt ctctatatgt caaagattga
    26161 tcattacaaa caacagcaat ttgatctgga gtttttaata cttgcgcttc aaacaaatct
    26221 tgaaatgatt gaaacaagtc tatgcctgtt tgaaaagtat tcaatccttc taacaactct
    26281 ttttcttctt cttctgcaat aatacaaata tctttcaatg ccaaattcgg gttttgtgaa
    26341 acttgcttta aaacataaca atacgaattg gcaaactgtt gcaaagaaga gaatgaacgg
    26401 gacttgcaag aaatttgaaa ttcaaattca ttatgtattt cattccattt tcttcgtatc
    26461 cataggacta aattattctc tgcgtattct tctagtgaat tttcattatg taatccttcc
    26521 atcccgatta caatttgaaa aggagttaaa ttgtgtttaa ctaataattc agagagcgga
    26581 tactcctgat tttcataccc gaataaagtc gtttgttcaa tctcatttac taattgttta
    26641 aaggggtgat gcggatggat ttcacttcct aaaggaatca acttattaag attctcactt
    26701 tgttcaagat tcttttcaat tataggaata ccaatggtaa ttctttcttg atctgtataa
    26761 tgtgccaaac aaacccttaa agcggcttga aaccagctaa ataataataa atcttgagac
    26821 ttacttattt tttgtatact tttactaaat tctacattca ctctgacttg aacgtactca
    26881 caaggtgttt ctttatttag ttggtaatcg ctattaaatt taaatacaga aaaatcgaga
    26941 atctcggaag ataattgctc cttccaaaac gcttctactt ctttattttc atgaattgaa
    27001 cttcgatctt taatgtgcat ttttatcttt atccccctaa tattcatttc ttctactcgt
    27061 taatttttaa gccaacttca agcccatgga gaaacacttg ttgattatcc aaacataaaa
    27121 attgctgaat atcttcaaat ttcatatgac caactgaaca aacccctaaa tttaatgttt
    27181 cagcaaccat atttaaggta gcagtgataa tgcctgactc aatacaagca aataaatatc
    27241 catctgaacc gtatttcggg atagaagcgt tcgcattata aatcaaataa actgagaatg
    27301 cagattgagt aaataaatcc tgattaatta actcatgatc acttttgatc acttgatcaa
    27361 tgttgtttac aatcacaaga ctgttttttg atgggttata ataataaaat ccagctttca
    27421 taccctctat acgttttggt tttatataaa caaagatatc aatgggatag agcccgcctg
    27481 cacttgcgta atgatagtat attttttctt ccctaacctg ttttagagtt gataagaatt
    27541 gggaaaattc cgaaaaacta atatgttttt ccatatcaaa ttgacgacaa gatctacgtt
    27601 ccttaattat agtaggtagc tcatttgttg tttcaagttg aatttcggtc gaccgtgcag
    27661 caacgtgcgt gcgatttaat tgttcactca tatacttatc taacttttct ttagaaaagc
    27721 gaatctggtt gctatatgga tttgaaaaaa tcttttcttg tgaagaaaat acttctcttg
    27781 ggtgtaatat gttacttact aacacacgat tttttatcat gagctctatg tttttttgtg
    27841 tctcttctac atttcctaat gaaaagcgct ctactagttc actgattttc acaccttttt
    27901 gagccataaa ataaagatca ggaaaccact cagacagaat acctgtaaat ctcatttccc
    27961 ctatcaaaac ttcattatgc aacttctccc aatgcttaat cggagaccag taataaattt
    28021 tctcgctcat ataaccctcc ataaacgttt aacttatttt tgaaatgcaa ttttctaatc
    28081 tacaaaaatt tttttagatt ctgttccttg tctcatagtg attataaata catgcacttt
    28141 aacgaaactt gaaaataatg aaataacttt ttcttcatta aaatttttta tttcatcata
    28201 aaaaatgatt tttttttgga tatttcacat cctttcccat agtaatccta taaggtataa
    28261 accatttata acattgagaa tattcatgta tttccaatgt gaaattattg taatggattg
    28321 gagagcggtt gaatatagtt attaaatcaa ataatgttga gaaagtttta tttattatat
    28381 cgataaaatt ttatgatgta atttattaca aatagattaa gaaaagggtt ttaaattttt
    28441 cttaatcagt tagtgtgaaa atatcacata ctattacata gaatcgagtt acttacattt
    28501 catattcaaa atagagaaaa gacaccttga atggtgtctt ttctctattt taattccata
    28561 tactttttac gcctttgtta tttttaaacg atttgtagga attaatacaa ctcaaatatc
    28621 tagttcgtta tatgttcgaa tatataataa acattatctg aattacgaat gtatttcaga
    28681 taattttata aataaactca aagatatctt cttctcctac tgccacaaaa gaaataatct
    28741 attgcttatt tcttttatta aattgtaata taattacagt atgtgaaatt atattacatt
    28801 aactttaaaa acgaagtgag aataatcttc acttcgcttt tttcatttgc aatccttatt
    28861 aaatttgctc aatgcagtat ttatttccac attcttcgct tttatttaat cggtttctct
    28921 gtttttaaga caaatgaact taatgtagga actttaattt tattgtcatg gacaacataa
    28981 agtggtttac ttcccgcctg cttgctgtct actagtactt tccaaggccc tttcgatgga
    29041 agtgttattt caacagcttc tctatttgca ttgtgagcca ctgtaaagta ttcattttta
    29101 ttcccctcta ttgtataagc tacagtattt ttcggagcat caataaatga tacgtgtgtt
    29161 tttatttgct ctgcagatgt cattcgaaaa gctgagtact ttttgcgtaa ttctattaaa
    29221 cccttcatat aatctacttc attattaaac gttgcacggc gcagccaatc catctggtta
    29281 attgaatctg gagatttgta actattatga tcaccatatt tcgtccgcat aaactcttgc
    29341 cctgcatgta aaaatggaat tccttgtgat gttaataaaa ttgaagaaga caatttgtgc
    29401 atttgttttc gcacttcttc actgtcacct gaattagtta actcaagttt atcccataat
    29461 gtatgattgt catgtgcttc cacataagtt aatacctgtt ccggatcttg ataggtagac
    29521 gaatttgtat cgtagtcaat acctgccgta ataccttttt taatacgatc ttccatgttt
    29581 tcctttccat ttataaaacc attttccttt tcctcaaata cactaccttt caacccatca
    29641 cgtatattat cgttaaaatg agcaatccct ttcattttct ctgcattttt ttgatttgct
    29701 ttcagctcag ctgcaagagg tgtatttaaa tcccatcctt ctccgtgtag tataatagaa
    29761 gggtcaattt gattaacagc tttacgtatt tcattcatcg tttcataatc atgaataccc
    29821 attaaatcaa aacggaatcc atctaaattg tattcttttg cccaatatgt gacggaatct
    29881 atcataaatt tcctcatcat ttttctttct gaagcagtat catttcctac tccagttcca
    29941 tttgcaaatg ttccatcttc attgtaacga taataataac ctggaactaa cttatggaaa
    30001 ttagattcag cagcgttata catatggtta tatactacat ccattaccac acgaagatta
    30061 ttatcatgta gtatttgaac catttgcttt aattcagtta ttcgaaaagt tggctcataa
    30121 ggatttgtag aataggagcc ttctggaacg ttgaaatttt tagggtcata tccccagtta
    30181 tattgcggtt catttaaagt ctcttcattt actgaagcat aatcaaatat cggtaaaaac
    30241 tgaacgtgag taacacctag atcctttata tgatcaagtc ctgtttttac accttctggc
    30301 ccttttgttc ctttttctgt tacacctaaa tacttccctt tctgtttaat accactttca
    30361 ggttggatgg aaagatcacg tacatgtaac tcataaataa tagcatcttc cggattttta
    30421 aattttggct ttttgtttgc tttccatttt ttcggatttg tttcttctaa attaacgact
    30481 gcacctttat ctccatttac agaagcagca cgcacatatg gatcaaccgc ttcagtccat
    30541 gtatcaccaa ttttgacctt atacgtataa aagagccctt tttgattccc ctttagttct
    30601 gctgtccaag ttcccttttc accttgttgc atgtttattt cagcacctat tttatcgttc
    30661 cagtttttat atgtaactaa cttcgcttcg cttgcagtag gagcccataa acggaacttt
    30721 gtatgttgcg cggtatatgt attccctaaa tcgttaccac tataataaaa taaattatca
    30781 aattcctcgc tacgaatgac tttaccaatt tcagtattcg tatcagctaa gttttctatt
    30841 ttaactttgt atgtttgttt taaatcaatt ttctgttccg taattatttt gaccttatta
    30901 gtaatatctc cactatttat atcataagga ctaatatttt taattttaat gccttcaatt
    30961 tcaattttct tttccctaat atgaaacggg acattagtcg ttatggtaat ttcatggaaa
    31021 ctatcaatag ttgctttttg aattgagaga tctgaagaag gcttagagtt atatactttt
    31081 tcatcgcccg aaagaatcca tacttcagca cgaccgccct ttatattttc aatccaacga
    31141 tccccaccat ctttttccca ttcatttgtt cgaactataa atcctacacg attatagtca
    31201 ccgtctattt ttatcttagc gtattttcca aattcatctt caccagtaaa ttcataagat
    31261 gtaccatttg cattttctcc ccataaccaa agattccagt cttttgtatt tccaagcttc
    31321 tctttgtaat gaatgataac ttcagttgtt ttcgaatttg aaactgcctt cacaccctga
    31381 aaggagaaaa cagatgataa cataacgatt aaagtaagta ataaaactgt tttgttaatt
    31441 aatcttttta taatttgcac cacatacacc ctttcttcaa atattactag cgatttatta
    31501 tgcttacact gaataacact gcttaaatta atctagaaat ctcttttgct tcacctccat
    31561 attggctatt ttcacgtatg tatttcaatg accttttaat acgaaagcgt ttgcataaat
    31621 gcttaaaaaa atagatttgt gtatgccctc atatatttgt aaatgctaaa aggtcagggg
    31681 aatcatttta aagcaatcgt ttgttatcgt tttcatttta tagactttct atcaagaggt
    31741 caatatatta ttaattttct gtttttatat actttaaacc ttatttattt gtcgcaactt
    31801 cttacagata acgcgcctaa ttattgctta gtcagtttat tttcaacaat acatcgctac
    31861 gtaaaaaagc taatatcctt aaaatgatat tagctttttt cataatgtat taatatatga
    31921 atgagaacta taattctaaa ttacttaatt tttgctgcat caaatgcctt ttgaactgct
    31981 tgaacttcag ctgtattcgc cccatattta ttagttgcca ctcgaataca tgctgatttc
    32041 aattctttga aattagaagt catgtttaac tcatcagtat ttgcataata gaaaatatca
    32101 aacattttat cttcaccaat tcctttaaca gttactccgt tatgagttcc gccttttgca
    32161 atgagatacg caactttatt aataatactt gaattaaaat gaacaccgcc ttgatcccat
    32221 ccattaaaat cgttaaattc actgtaatca tctggataag gtactccgag tgaagatgga
    32281 acagaagctg ggttttccat atcacggaaa acagatcccg tttgttctcc cattgtccaa
    32341 ttaaagtttc cattatttac gtatttctca atagatgttc ccataatatc agatagcgcc
    32401 tcattaatcg caccggattc accgtaatat tcaagattag attcactaga agtaacagca
    32461 tgtgtaaatt catgtccagc tacgtcatat gctttaacaa taggatcccc atatacaagc
    32521 atacttccat tattagcact taatgcattc tgccaatttt tcggatcatt cgtctcttca
    32581 gaatcccaag catgtacaac tgaaactacc ttttgtccct tattatcaaa gctattacgt
    32641 ttgtatttat ctttataaaa atcaaatact tttgttgcta agtaatgagc acttactgct
    32701 tttggatcgt taaatgttgc cgaagtacta gtcgctaatg taccaggata atagctttct
    32761 tctttagtaa tatctctgta attcacatca tatgtttcaa ttccttgccc tcttgtataa
    32821 tcagcaagag catatttgcc attactttgt ttagagatac caaatgaacg agaaatacct
    32881 aaatcatctt ttcctgttcc agttaatgat gtaagactgc tttgtttact tttctttaaa
    32941 gctccaacta gtttgtcact agcttttaag ttagattctt gtaccatatt ttttaacata
    33001 tcaccatttt gtgcatttac taaataagta ccagaaacat agtttggtgt tgcagcttca
    33061 aaggtaactt ggtatgcatt tttagcttgt ccattatttt catcaacaaa aataacctct
    33121 ttaacttctg gctcagtaat aaacttgata tcgttcccgt acttcgtata aataaattgt
    33181 tttgcttcat cttttgacag attaataggt tttttcaatt cttcttgttt tagattttgc
    33241 gcgctatcac ctgaaacact tttaataaca ccattattat ctacgtgtgc agttaattga
    33301 tgaccatata cttcttttcc ttcgtatgtt tgctgcatac gtacaagtgt agttccatca
    33361 tacgaaccac gtttttgaag gactttataa tctactcctg cttctccatt gacttgtttt
    33421 tgggagagag cttgctctgt tttctcctta agtgcatcct ttactacatt ttctggtgtc
    33481 ttttgtgacg gttgtgtcag ttcacccgaa cggaacgatt cttcctgaat ttgaacttgt
    33541 agttgatctg tttcctctgc atgacctacc ccatatggtg ccacagctgt taaagctaat
    33601 ccagttgtta atgctacctt agttaatgtc tttttgtttt tcattatttc acctcgtata
    33661 atttttgaaa tagaaagctt gtacaaagta tactgtctat ttctgtcgga aaaaagagaa
    33721 aatacacaat ttatgtaaca ttatgcaaaa ttacataaat tgtggtcaat attataaata
    33781 atgaacggaa cacatatgta cattaatttg aataaaagag agtccttata ggcgctcatc
    33841 caattggtta gttattaatt atctatattc attgtaataa aagtatactt acctctaaat
    33901 aacaacataa aaacccactc tttactattt taagagtggg tttaatgttg ttaaaataac
    33961 aattactata agaaacctta taatttatat ttttttagta atcctactaa gttttttgta
    34021 aaattcacct ttcgttttta tatgcttaaa ctgatttgga ttaatatttg ctttttgtga
    34081 gagtgctaca atctcttctt ttgtaattga atctttcgta tttatagatg ctatatttgt
    34141 gtattttccg tcttctgttt ttggaatttc taaaatccct ttattcacaa gatcaactac
    34201 agccttatgc tctgaagaat gtaaatctac accagtaatt ttccaattac gcataacttt
    34261 tggcgtgtat acaccgttct ttacctcttt taaatatgta atagcaaggt tacgaatggt
    34321 tccacctgtt tctccaaatg cattctcttg tttagatgac caaatttgtt caaacttacg
    34381 cccctctaaa gctcctcctt ttgcctgaag agcctccatt ctatatgcat tcattcccag
    34441 cgtcataaca tcgctcattt tgattggttt gtttgtacga atagagcgta aatttgtaat
    34501 tctacttccg tatggttttg ttaagtcaat ttcgtatttt acgcctccaa agaaatcgtt
    34561 cgtactgtat ttagatgcac ggcgggtttt atcaaagcta acggttacat ctccggcacg
    34621 agatgagtta aaatatcctg ctgcccattc catatagtct tttaaatctt ttccagaaat
    34681 cttatatact gtaatttctc ccaaggcata ttggtaatta tacgcaatat cttttttctt
    34741 aataggacct gtatccaaac gggcataatc attatcaatt tgatgggcta ctacatctgc
    34801 tttactgtag tagagcatga cttcatgaaa gaaatctgat aaaggtgttt cttgaatctg
    34861 aacacttggg atacccttta tttcattttc aggaacaaga tttctaccct ttaattgagc
    34921 gactacaaca tttgcatctc ctctcgcata ttcgtgaaaa ggtgttagtg tttcttcaag
    34981 tgtaggatca gataatatcg ttgttccatc agcatttttt acaggtatag cggtagcagt
    35041 tttatctttt aaaaccaact tctcatcttg ctttgtaaaa gtaaggtcaa tacgtgaaat
    35101 atgtgttcca tatttatctg gttctgtaat aattacgcca tttacaactt ctttttttac
    35161 aagtttatgc atatgagccg caaaaatagc gcttagttcc ggacaagcat ttgcaatatc
    35221 ttgtacacca gtaccaggga taccattctc attttctagt cccatatgca taactcctac
    35281 cattacatct actttacctt ctaattcctt aattgccttt ttcgtctctt ctaccggatt
    35341 tttcaccact aaaccattta agtgatctgt ccctttttca aaatcactaa tcattggtgt
    35401 attcatacca ataatcccaa ctttaattcc acctttttct acaattgtat atgcaggaag
    35461 aaagcgctct ccattttcct tataaatatt tcctgctaac gtttttccct tatattgctc
    35521 actaactttt ttcaatgtat ctaatccaaa gttgaattca tgatttccaa atgcccaggc
    35581 gtcatatccc attgtattca tcgctaccat cattggcgat tgtggcttat cgttgaataa
    35641 ttctactgag tttccttgaa ttgtatcccc ggcatctact aatatggtat tttgattttc
    35701 ttgacggacc ttctttataa ccgtataaag ctgcgtcaaa cttccactca tatttgctcc
    35761 atcaagcgca taatcccaag gcataaatct gccatgaata tctgcagtac ctaacaatgt
    35821 aatattaact tcagattcct cagccttaga gataggtggt ttgactatta ctgctgttcc
    35881 gagcagtaat agaattacaa agtaacatac atagttcttc catttcattt tttgcataat
    35941 aataatattt ctcccctttt tgtactttcg taaagttgtt tgaactttaa aaatgtaact
    36001 tattattcgg gaaacttcaa ctacaaaaga taattttgaa ggtggttctg ttgcaaaaat
    36061 aaagagaata aattgcatac atcccctaac agaattgtat tttatcgttt cctgacagaa
    36121 taccccttcc ttaagggtgt gaagtgtact ttcaaaataa ggacatatca ttcattatca
    36181 tttcaattta ttaaaacgtg catatacaat atgttatgat gattaatttt ttgaatttcg
    36241 ttgctgattt atttcattct aaataaaaac actttcaaaa aaaataaccc cgctcttcat
    36301 ttaagacggg gttacactta tacagaaaat cggatagttt tatattttct taagcttatt
    36361 ggttactttc aactaatttc attctatttt tgttttcttc tgaatcaata tgaatcaatc
    36421 gtttcccctg tttataatac gcatcaataa acagggaatg atttttactt ttcaatttca
    36481 caaagcaatt ttatctcttt gatttgttct atatgacgct gttcatgcaa atagattaat
    36541 tctatccact gatcaagaaa taattctcca agagctggat gcatcactga tttttttact
    36601 aatttagatt catcttctat tgtactcaga aaacgcatca attcttttct agagtcgttt
    36661 aacaaatcaa ccatttgcag cacttcaaat ggttctatac ttggttcaat catttctggt
    36721 gctataaact ttttcgttct atctaataaa atagtgtgaa tttctttacg ctcattttgg
    36781 gtactatcta acttttttaa tcctgacgaa ataactgtta taattctctc atctaataaa
    36841 actaaatgat gacaaacttg tgcaatactc catttatcct tatctggttt cctattaaat
    36901 tgagcatcac tcaacaaatt aatttcctca actaattgat ttctcgtttc ataaaacttg
    36961 ttatttacaa atgtatccat gtggattctc ctttcattgc aacctacata cttaaattcc
    37021 tacgctagaa atattatctt cgaaaaaaga ttttctttca ctactattcc aatttcattt
    37081 taaagccaca aatgaagtta tttgtttttt gtatattttt aattggcaca aataaatcaa
    37141 cctttaattt tccttctaaa tcttcagcaa cattatttaa gcaaaactct aaattatctc
    37201 tatcataatc tgcatcatac tcactattta gtagccactc tgcatacatg tattgatacg
    37261 cttcacttaa tttatgaggt tcaccataga actggtatag accatatgta cctccatcta
    37321 atcttttaaa ttgcacatca tgatactttt ctttatcgaa gttttcagga atcgtaacac
    37381 atgcatcatg ccggcactta tgacttgcaa caagttcagg attatctaat gatattccga
    37441 taaatgattg ctctggtgga taaaggttat tttcaattga ccagttcagt aactttcccc
    37501 agtgattttg cggttcaaag tagctaccag ttcgtcttat atacgctact tctaatggtg
    37561 gtaatttttt tataacaact ttcatttaca tcttctcccc tataaatacg tacactgttt
    37621 atttagcttt ctttaatatt tattccttct taaataaaaa gaattttcta atcacataaa
    37681 gtgaaccttt aatcagcggg agataaattt taattgtaat ataattgatt actactacta
    37741 aagtagtatg tactttcata cttttatttg attttaaatt ctttttaaat cgatatatta
    37801 attgtaagga aataaaaagt tggaggattt taattgatta aaggaatata cgaagcacat
    37861 ttaccagtga gtaatttaca acaatctatc gaattttatg aaaaactagg attaaagtta
    37921 gcctggagcg atgagtcaac agcattcttt tggattgagg atgggaaaag ttggctagga
    37981 ttatgggcgg gctctgaata cgaaacaaaa tatcatcctt ctttacgtca tattgcattt
    38041 agagtttcat atgaggattt aaaagaatca ttacattggt tacactcact tcaaattaaa
    38101 accgttccgt ttggaagtaa tgaatctatt gaaccctttg tccgtccaca tcaaggtaat
    38161 gcatctgttt attttattga tccagatggt aatagcttag aacttatttg tcatattgtt
    38221 gtacctaatg cactaaaaca tataactaat aaattatcat ttaaagattg ggagacacta
    38281 ttagctgaca catttgaatg aatataagct ataaatcata atggctcgcc tttattttta
    38341 taacatgtat aacaatcgtg aataataatg tcctatcaat ttatcattaa ataaatgtaa
    38401 aaaatgaccc tatttattca tttttcatgc gtatgtatgt acatttgtga atttattcga
    38461 tatattatgg gtattgaatg attacgaaaa gtgtataggt cgcttatata acaccttata
    38521 tttttatatc cgtgaaaact acaaagtgta tgaaaatcca tttgtcaaat gaatttagtg
    38581 cggaaggagg tttgtggtta cttcataggg tataataatc agttttttac tgataaaaat
    38641 ataggaggcg acataatgtt tcgtacgatt tcaaatttca tgagagtagc tgagataaga
    38701 aggaaaatcc tttttacact agcgatgtta atcgtttttc gaattggcac gtttattcca
    38761 gttcctcata ctaacgcaga ggtattaaaa gtacaagatc aagctaacgt tctaggtatg
    38821 ttaaacgtat ttggtggagg agcactgcaa cacttctcaa tctttgctgt aggtattaca
    38881 ccatatatta cagcttctat catagtacaa ttacttcaaa tggatgttat acctaaattt
    38941 tcggaatggg caaagcaagg agaaatgggc cgtaagaaat cagctcaatt cactcgatac
    39001 tttacaatca ttctcgcatt catacaggcc atcggaatgt cttatggctt taataatata
    39061 gctggtggac aattaataac agatcaaagc tggactacat acttatttat tgcgacagtt
    39121 ttaactgcag gtactgcatt tttactttgg ttaggcgaac aaattaccgc taacggagtt
    39181 ggtaatggta tttcgatgat tatcttcgca ggtctcgttg ccgcgattcc aaatgttgca
    39241 aatcaaattt atttacaaca attccaaaat gctggcgatc agctattcat gcacataata
    39301 aaaattgttt taattggact cgtaatttta gcgatagttg ttggcgttat ttacattcaa
    39361 caagctgtac gtaaaatacc gatacaatat gcaaaagctg tttcaggaaa caatcaatat
    39421 caaggagcaa aaaacactca tttacctctt aaagtaaata gtgctggtgt tataccagtt
    39481 atctttgctt ctgcattttt aatgacgccg cgtacaattg cgcagctctt ccctgattca
    39541 agcatatcaa aatggttagt tgcaaatctt gatttcgcac atccaattgg aatgacactt
    39601 tatgtcggtc ttatcgttgc tttcacatac ttctacgcat ttattcaagt aaatcctgaa
    39661 caaatggctg agaatttgaa aaagcaaaat ggatatgttc ctggtattcg tcctggtaaa
    39721 gcaactgaac aatatgtaac taaaatttta taccgtttaa catttatcgg tgcaattttc
    39781 ttaggtgcaa tttctatatt accgctcgta ttcacgaaaa ttgctacgtt accaccttct
    39841 gcccaaattg gtggtacaag cttacttatc attgtcggtg tagcactaga aactatgaag
    39901 acgttagaaa gccagcttgt aaaacgtcat tataaaggtt ttattaaaaa agtgaattaa
    39961 ttataaaaaa cacagttgga aaaataacca actgtgtttt ttattgtatc agtcctgtaa
    40021 tatacagggc tgttgcttta ttaaactaca tctccttctc taataaccgc ccttttttga
    40081 aataagtccg tagtgttgaa cgattggtca agaatacacc tatcaatata aaacaagccc
    40141 ccattcccat tgtaggattt aaaggttctc ctaaaatgat atatcccaca attattgcaa
    40201 ttaatggtga tacatataac cacgtcgatg gaaatactgg atttgttttt gataagagcc
    40261 agtaatataa tccgtgtcca ccgattgatc cgataaatat gagatataaa ataggccatt
    40321 gtacactcca tgaagttaat acacttacat ttggttgttc tacaataata gatgcgatta
    40381 gtagtaaaat ccctccataa aacatttgaa taccattaat aagaaatggt gatacatttg
    40441 ataaatctga aagtatttct ttcgaacgaa tagagcctat tccgtaaaat aactcaccta
    40501 taactaaaac aatacaagca atactccata tgaaacttac ttgttgatgc attcctggta
    40561 aagaaacaaa tataacacct attagtgcga taactaaagc aacgagttgt tccttttgta
    40621 atttctccct attcctcttt gcttgtatta ataaaatcat cattggtccc gtagcagaaa
    40681 gaacagcagc taatcccgaa gaaatatatt gttctgacca atataaactt gcgaatgtca
    40741 taaatgttaa acaaaatcca gcatacataa tacgttttga aaatatatgt ggcataattt
    40801 cttttcgctt taatttaaaa ataatcataa ggattatacc cgctaaaaag aagcgaattc
    40861 ctgctgaaaa caacggtggc gcccctgctt caattccaat ttttatcgtt aaaaatgttg
    40921 tcccgaaaat aatacatact aaaatgtaat taaaaatgac catttttctt cctccttttt
    40981 actcttaaaa tgagtataga gggtatggtg tataacagtg tatcggtaca tataacagtt
    41041 acttcaagtt gtagttgatt ccctatatat ttttcgcttt aattaaatta aaaagaaaaa
    41101 taggtgaacc tatgaagatt gtattgcgta aagaatcaaa cataccgtat tacaagcaaa
    41161 tatatatgca aattgttgaa agagtacaaa gtggtatgct ttcacatggt gaatcccttc
    41221 cttctttacg ttgtatggcc acagatttac aaatcaatgt attaactgtt cgtaaagcgt
    41281 ataaacagtt agaaacgaaa gggtatatac gcatcgaaca aggaaaaggt gcttacatat
    41341 ataaacgtgt aaagaaagat ttcaaaccga taccgtataa atggcaacaa tcaagatcta
    41401 ttaatgttat gcgttctcaa tatgcaatga ataagcaccg taaatattat gatttttcac
    41461 aagcaattct gtatcctcgt ctgttaccaa atccattttt ggcagacgaa atgcataaat
    41521 tgctagataa aaatccgatg ttgttagcaa cttatgggcc agttcaaggc gattatgaac
    41581 tgcgagttga aatagcaaat tacttaaatg aacaccagaa attagtgacg gacccatctc
    41641 aattattaat tacaagcgga gcacaacaag gaattgattt aattgctcaa acattattaa
    41701 aacctggaga tatcgtatta gtagaaagtc catgttacag tgctgcgctt gacgttttca
    41761 tcaataaagg tgttcaaatc attcctattt ctcttgataa tcatggagtt cgctccgact
    41821 taattgatga tatttgtcaa agtaaaaatc ctgttttatt gtatacaaat cccaccttcc
    41881 agaacccgac aggtacagta atgagtaaag aacgaagaat ggaacttata gaactagcgg
    41941 agctatatca attttttatc attgaagatg attctttcgg agaaatatat tttgaaggtg
    42001 ctatagtccc accaccaatc aaaagttttg ataaggatgg ccacgtgata tatataaaag
    42061 gatttagtaa aacgttagca ccaggactcc gtatcgcagt actttttgcc gatggtccta
    42121 tttttgaatg gctatatgca gtgaaaggtt ccatggatat cggtagtcct ttattaacac
    42181 agaaggcact tctacctttc ttacgtgcgg aacgtatgaa aaatcattta gaaaaattac
    42241 gtacagcttt acaaatgaga cgtgatttaa caattgatat attatcgcca ttaaaaggac
    42301 taaactttga gataccaaat ggcggtttta atttatgggt gacactgcct gattggatag
    42361 atccctttac cttattacaa aaagcaaatg aagtagatgt ctctttttta ccaggaacag
    42421 cttgtctatt aaactacgaa acaaatgata accaattaag aattagctat tcaatgttaa
    42481 acgagaaaga tatggcaatt ggattagaga aattacatga tacaatacga aacagtattt
    42541 gttagaagta ataacacaat agccaacaat aaataatacc cgaaaatgac aatgtgtagt
    42601 atgggctatt atttattgtt gagctttttc gttattctta acaaccgatt ttaaaacttg
    42661 tctttctttc aattcttcaa cactaccata ttgatcaata acaattgctt tcatttactc
    42721 tcctccttgc tgtttatttt aataacatac aattatttct caattttttt tgtcttgaat
    42781 taccatataa ttatttttgg gggtaattat gcaagaagca ttataaagtg aaactttaat
    42841 cagccctcac caattgggct cctactgctc gttaatactg gatgaatttc aaaacaaatc
    42901 ttacacacat cttagaatca tccaaaactg ttttattaat taaattcaaa agaaatgagg
    42961 ctaactatat gagtgaaaag atatttaaaa taaacggaat tgatatatgt acagaaagct
    43021 ttgggaaccc taagaaccct gctattttat taattatggg cgctacatgt tccatggttt
    43081 attgggacga agagttttgt gagctgttgg ctagtacggg gaaatttgtt attcgctttg
    43141 ataaccgtga tgttggacgc tctgttgcct acgaacctag aacttccaat tatacagtaa
    43201 cagatatggc tgaagatgca attggagtac tagatgctta tcatattgat aaagctcacc
    43261 tatttggtat gtcattaggt ggtatgattg ctcaaattgc cgctataaaa catcccgaaa
    43321 gaattttgac gctaacttta ctagcgacta gtgtaatagg atctgatgac aatactcgcg
    43381 atttacctcc aatggatgaa agaattttaa cacatcatgt aaatggcaca agtatagatt
    43441 ggacaaataa aaacgatgtg gcagagtatt tagtttcagg atctcgtcta ttatgtggat
    43501 cagaacgaat atttgatgaa aatagagttt atacacaagt aaaacaagaa atagaacgcg
    43561 caaataattt attaagtatg tttaatcatg ctttacttca aggtgatgat gcatatgaag
    43621 gtgtacttca ctccatacaa gcacctacat tggttattca cggaacagat gatacagcac
    43681 tcccattcga acatggcctc gcactaattg atgaaattcc aaactcagta ctattaactc
    43741 ttaaaggggc aggccatgaa aaccatccag atgactggga aagcataatt actgctgttt
    43801 ctaaacatac atctgaaatt tagacaaaca aataattaac aaaaggggca caaattgtat
    43861 tgtgcccctt ctatttacaa acaaaaaccc atcactgtat tcgtatgtat agtgatggga
    43921 cttcttatat ttttctatgt ttaaaaaaat ggacaatcta attgatcaac agattcccat
    43981 aatttttttt ttgcattttc ggtggatgta tttgtttcta gtgtcatgtt tttaaaaggg
    44041 tttacttcaa cttttaataa ggatgaaggc tccacatata atgagaaaac atggctgctt
    44101 ggtaaagctt tagaaacgtc aatatctcct acttgtttaa atagttgctg cgcagcaaaa
    44161 aagaagaaat tagttggatt tgattgttta ttcagccacg caagcatttc aggtgatacc
    44221 gatttatgaa tattgatttt tactcgatca ccacgtttat atcgcctaga tcgcatactt
    44281 ccaccaacta acttatcgtt aagtttgtaa atcctaactc tttttgctta tgctctctat
    44341 attttggcga acaagtatag actaataatc ctcgtgcatt ggtaaataac ggattatcta
    44401 caaagattac atttttgagt cgtccttttt gctttaaaat catttttaaa ctgtttttaa
    44461 taattactgc accaccgcca taaataaaca cgtatggatc gtctttcata tcatcaattt
    44521 tatttataat atctgttgca acacgagctg ctaaacctaa tagtgccggc tgtgattcct
    44581 caactaataa ggtatttctc ggatgcttat catttaaata aatttgattg aattctgtaa
    44641 tactatcaat cgtcttagtt ggatactttc ggttccatct cgtgataatt tgtaataacg
    44701 tctcttttac accataagat aaacctttac ttagttgcgg acggaaattt acccctaatg
    44761 aaacaacttc ttctgtcgtc cctgcaccaa tatcaaaaga gagtagagtc ttatctacaa
    44821 aatcaatttc agaaacttga ttcggctcac attctatttt atgtttcaca acatttcctt
    44881 cttcatcgta tacaatgccc cacgtcccag atgcgccctc aggcaggcat ttacaatact
    44941 caattgaaac attaattgtc acatcgcgtc cgttcggata atggaaaatt accttatgat
    45001 ttcccatata acgttttgca ttttcagcag ctatttcttg tgtaataagc tgcataggaa
    45061 gagcgacaga taaatcataa cgaatattaa tatggctaga agttggactt tgacgcatag
    45121 cgcttaccgc caaacctgat agtattgtaa taaccattaa ctcatccgtt gacttatttg
    45181 atttcttctc tacctcagta ccttttaatt gatcttgaat gactttttct ccaacgatgt
    45241 atcgtacatt attaagcatt aacgatggcg aacttatagt cacatcaatg tggttttcta
    45301 attcagataa tgaaacatct acctcatcta agagtcctgt cggctcacct atatataaag
    45361 aataaatact cggaataaaa atagggtctt gccctttcac cattaacttc aaaccgttgt
    45421 ttcctgcatc tgcaccagct tttaaaagta tagacataac taccccctaa attaatctga
    45481 catcccttcc aaatatatgc gagcccattc ttttacattc aaatgtattg taatttttta
    45541 tttatcataa aaccaaaata ttgcatactt acatatttta tgtaaaaagt atttgacatg
    45601 atacttttcc aattttatac ttatatttgt aaagagtttt ttacaatcga ggggggcaat
    45661 tatttattga atactaaaaa aactattttt atcatcattg ttttagcatt aattgcaata
    45721 atagtacatg gcacatataa atacatcact gaaggttcta ttttgggtgg tacgattttt
    45781 gctatttcgt taatacttag taatttaatt aatcacatta cttggggaga tccccacggt
    45841 gtatcagaag aaagtcaaga tgaaatgggc caacaaatta catataaaag ctttaaaatt
    45901 gcgtattttg tgcttgtagt tataatgttc cttttattaa tcttctccga aggattttct
    45961 atgggggcta atttagatgg cgttaaaaac ctccctctgt tcatcgcaat ttgctcttca
    46021 ttctttattt atcctattgt cgaactcata gttgcaaaac aatataagta aaaagatgag
    46081 gttttctaca tgtagaaaac ctcatctttt tatatttaca tactctctac aattgctttt
    46141 aatttattca cagtccgcca attcctaact gtagctggtg tatgtaactt ctgaaactgg
    46201 ttcattaatt tagaatttcg aatgctattt ttgaaaaaca aataagcaac cttctcatct
    46261 atatagcaat cttcaagttc acttttaaat gtaagcaatt gactactctc ttcttcagaa
    46321 agtacattag ctaaaaaagc aacatgaaca ctttcccctt ctaacaatga atgaacttca
    46381 tacggacatt gtttaataat atttataaat tcatcatgtg ttcttagcat gactggaaca
    46441 tcgaaatcaa attcattttt catttcagat tgtattcggt cctttagaaa gtttatacct
    46501 tcctcagatt cgaacacgat attaccactt tgtatatatg ttttcacatg ttttaattct
    46561 attgattcaa acaatcgttt taaatcagcc attttgatta ctttatgtcc accgacattg
    46621 attcctctta gtagtgcaac ataaattgtc atattattcc cccacaataa aatgaattta
    46681 tcaactgaat tgattttccc actcatattt ctcggatatt tgttttaatt cttctaacat
    46741 atcatgaata gataatacct cgaataaaat aatagattca cttgaaaaat ggtgatgata
    46801 atgatctggt ttataatctt ttaaatcatt tttataactc caaaattgct tgtctaattc
    46861 agcaataagt ttaaaatgtt cctcatcaat ttcattacaa cggtttctca atatagcaat
    46921 tatagaataa gttgtttgtt gtaatatttc cctttcactt tgtgaccagt cacaggtctc
    46981 aattgacact cgagctaaat tatctatatg gtaaatgatt
//
