LOCUS       NZ_PVRL01000007        26572 bp    DNA     linear   CON 21-MAY-2024
DEFINITION  Bacillus thuringiensis strain NMTD81
            NODE_7_length_279520_cov_17.8551, whole genome shotgun sequence.
ACCESSION   NZ_PVRL01000007
VERSION     NZ_PVRL01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis
  ORGANISM  Bacillus thuringiensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 279520)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., W,H. and Gao,X.
  TITLE     Genotypic and phenotypic analysis of antagonistic Bacillus spp.
            isolated from rhizosphere soil of plants in Tibet
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 279520)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., W,H. and Gao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) UG, NordReet, Marienstr. 27a, Greifswald
            17489, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. A5-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 14.5x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002998815.1-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 01:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,177
            CDSs (total)                      :: 6,068
            Genes (coding)                    :: 5,840
            CDSs (with protein)               :: 5,840
            Genes (RNA)                       :: 109
            rRNAs                             :: 11, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 1 (5S, 23S)
            partial rRNAs                     :: 6, 5 (16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 228
            CDSs (without protein)            :: 228
            Pseudo Genes (ambiguous residues) :: 0 of 228
            Pseudo Genes (frameshifted)       :: 100 of 228
            Pseudo Genes (incomplete)         :: 142 of 228
            Pseudo Genes (internal stop)      :: 67 of 228
            Pseudo Genes (multiple problems)  :: 63 of 228
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:59:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 22552
            Orig. end                         :: 49124
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVRL01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26572
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26572
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26572
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16572](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16572
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    576..588
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: strong, score: 26.12"
                     /tool="antismash"
     misc_feature    complement(1111..1124)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     15.94"
                     /tool="antismash"
     misc_feature    complement(1142..1158)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.57"
                     /tool="antismash"
     misc_feature    1598..1614
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.87"
                     /tool="antismash"
     misc_feature    complement(1609..1625)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.51"
                     /tool="antismash"
     misc_feature    1868..1884
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.87"
                     /tool="antismash"
     gene            3375..5072
                     /locus_tag="C6351_RS17030"
                     /old_locus_tag="C6351_17030"
     CDS             3375..5072
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016136171.1"
                     /locus_tag="C6351_RS17030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17030"
                     /product="hypothetical protein"
                     /protein_id="WP_000369378.1"
                     /transl_table=11
                     /translation="MDNLLQMFRDALLISEPIYKTNELVWNKWNAYFKDVENNNNKVLT
                     SPHASPSFTALVSWLEKKQESGITLLQIYAKIDSYKEEIYKEIEVFIEKEFQNVVHTNS
                     LILENDQNIDKPNIVNHEDYYEVNNSAVYYKLRDGIAKNQFEEDEISKVLQYPIETRSS
                     NGVAQLSSHKDEDLRLTNIEEAARWNTLVDDVMSNMDDLTADCLDAITIQWINEAKSPD
                     DFIDFSYEQVLEMCNIPKTVVKNKEYYRAEDKIKIAKRIAALASIFIYLNDENEVVVLN
                     DRDDDGERLELKREVIKRLFVLDSVVLWRHSVTNEYMGIESCRIKPGSFLTNYLYGSNN
                     TTALLSKKALEYNSYRHKYHKRLIRYLTWQWRIRQMYSSLKKPYSIGGDKGLLSVMDIP
                     KDWKPNRIREQLENVLMDLENEKVISHWEYSDPLDEQQIGKRNWFKNYYTNLGITILPP
                     EEMLQSMDRVIGKKIVEEPQEQLPEVTVVKEIKKTVESVEQIEKKIRDQILKVHNEKKV
                     SIREIADEMSISPSTLSRFCNYKTKRLSKKALEKLTKWCERQEILEKM"
     gene            complement(5234..5701)
                     /locus_tag="C6351_RS17035"
                     /old_locus_tag="C6351_17035"
     CDS             complement(5234..5701)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016090253.1"
                     /locus_tag="C6351_RS17035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17035"
                     /product="RsfA family transcriptional regulator"
                     /protein_id="WP_106081850.1"
                     /transl_table=11
                     /translation="MVISRQDSWTDDNDLLLASTVLQNIRNGGTQLAAFKEVAKLLART
                     PAACGFRWNSYVRKQYQEEIQQAKQDRKMGNNIPLSPSEKEKNSLSITLDDIILFLQNY
                     KDVNELTELQNQIEDLETENQSLLQRIAMYEEEYRMLLNHIDKTRNLIAVD"
     gene            6056..7705
                     /locus_tag="C6351_RS17040"
                     /old_locus_tag="C6351_17040"
     CDS             6056..7705
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688773.1"
                     /locus_tag="C6351_RS17040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17040"
                     /product="S8 family peptidase"
                     /protein_id="WP_088021323.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.3e-23, bitscore:
                     76.1, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIFKGILVSSIALTAFNGVGGLLPSEKSEVAYAATYNYTNKQLN
                     STVHKQVTKQLILKFKNEANLPYQDGIEKFIKEEKQDPELIGILAEYPNVTINRLFNSL
                     NPKEIKNLGKEIKDSDHISSNLLNYYIVETQDDIDVQALLTKIEKSSLVETAYLQEEEA
                     PPAERLPNLSVNPYDEPRLTRQGYLEPAPLGINAPYAWSIKGGDGKGTTFVDMEYGWLF
                     SHEDLVNQKIELISGQNKSEHHDHGTSVLGIVSAEDNNIGGIGIAPKAKVKVVSQIRDN
                     GNYNTADAILSAVNNMQAGDILLLEAQATYDGYGDKNYFPVEVKPDIFDAIRMGTNKGI
                     IIIEAGANGGNDLDQFRDRNGKQVLNRNSPDFKDSGAIMVGAASARVPHKRSYFSNYGS
                     RVDVYGWGNAVDTTDAKPSEFITNLYTSSFAGTSSASPIIAGAAASIQGIAKNNQGKVY
                     TPSQIRAILSDPSTGTKSNDPISDKIGVLPDLKAILSKLGFSPNLGNDSSIVFPEEQEI
                     NKGNKGNEGSTITFPKEDTANSEEDSSFIFPE"
     gene            8935..9108
                     /locus_tag="C6351_RS17045"
                     /old_locus_tag="C6351_17045"
     CDS             8935..9108
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429840.1"
                     /locus_tag="C6351_RS17045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17045"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_000429839.1"
                     /sec_met_domain="TIGR03731 (E-value: 7.8e-12, bitscore:
                     38.9, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLFDLDLKVEKSSNGVEPRVTSYAFCTPGTCACEDGPTFDSA
                     CCSVELTIYNCK"
     gene            9234..9407
                     /locus_tag="C6351_RS17050"
                     /old_locus_tag="C6351_17050"
     CDS             9234..9407
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429840.1"
                     /locus_tag="C6351_RS17050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17050"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_000429839.1"
                     /sec_met_domain="TIGR03731 (E-value: 7.8e-12, bitscore:
                     38.9, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLFDLDLKVEKSSNGVEPRVTSYAFCTPGTCACEDGPTFDSA
                     CCSVELTIYNCK"
     gene            9532..9723
                     /locus_tag="C6351_RS17055"
                     /old_locus_tag="C6351_17055"
     CDS             9532..9723
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014145.4"
                     /locus_tag="C6351_RS17055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17055"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_261982026.1"
                     /sec_met_domain="TIGR03731 (E-value: 6.2e-12, bitscore:
                     39.2, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVKKMENNLFDLDLKVEKSSNGVEPRVTSYAFCTPGTCACKEGP
                     TFDSACCSVELTVYYCTR"
     misc_feature    9942..9955
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.97"
                     /tool="antismash"
     gene            10001..13192
                     /locus_tag="C6351_RS17060"
                     /old_locus_tag="C6351_17060"
     CDS             10001..13192
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="C6351_RS17060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17060"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_106081851.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-148,
                     bitscore: 489.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2e-12,
                     bitscore: 41.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9.8e-39, bitscore:
                     127.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLYTPLDFFLLRTPTYPIDNFKSIIDIESEEEILDYILNNVLS
                     NEKIIEMLIVASPKLYEALLRLENNPDTKKKEQIILNLTKYLIRMSTRSTPFGLFSGVS
                     MGDFDDKTDIQIDDINHFTKTARPDMAWLLGCIKQIESDIENVKCLKVKVNHLTVTSGL
                     RANLLYSTQYGERSKATKKEVVSSSIKYNEVTQKVFDRAQEPILFSTLIDSIKSEYPNV
                     QEETIKQFVWNLFKNEYLISELRPILTNGNPFEYVINKLSEKEALTKYYVQLTKLKEDI
                     DIYNGLSLGEGKELLLNLFDKMREIYEVDTPLQVDLSIKTKHSTISKSIQNELSKVADF
                     LWVLTPKENINNELDHYRNDFLEKYGEYREISILELLNPDIGLGAPGGYLNPPSYKKVE
                     NPPVNQLNEFENYLLEEISKLLCSNNGDIREINIENKIYEKFKKKDMDLNTAAVSMELY
                     FRIISESFSNIDNEEYQIQLVPNAGSDGAGKTFGRFNQMLNEENQEKINKINQLEKSFY
                     EDTIFAEMVYLPDYGRSANVTISNSIRDYELCIGTNSSKDKKHTLSMSDLVVGVYQGNF
                     YIRSKSLNKRVIITTGHMLNIAGCHNLCRLLKELSNHGMVHWKLPIFSWMTKMAFVPRI
                     NLGKVTIIPAMWNLNLNMLDINVKELKKDFELFKKQFHKWCEEYNVPRYIYLFDMDNRI
                     LIDTKNNLHVKIIQKEMSSSKGNKVQFYEMGNEICKEWIEGDTGTYISEVVVPFVKNSE
                     VVEEKMKVHFNASHSIECDQVRTKALGSDWLYFRIYCNNNMEDEFIGRELQLICNNAVS
                     EGLADKYFFMRYSDNKKHIRLRFNMLNKDNFPKLISYINTHCNQLKAKGIVSNVAIDVY
                     EREVERYGGPELIGEAEDLFFLDSQFVQELIRLKENNLLNTSFENICIYSILDYLQGFG
                     LTHEEQLKLMEAVVDYKEYLEDFRKGKKVLVNLCNKNNVIDFGITTDNSNLYELLAARK
                     KQIKLYKEKIDDVEIQGKLFNVRENIILSVIHLHCNRLIGIDRVYEKKLNTLARHTLKA
                     LSYFYEQQNKILITH"
     aSDomain        10457..10738
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C6351_RS17060_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.60E-13"
                     /identifier="RREFam001.1"
                     /label="C6351_RS17060"
                     /locus_tag="C6351_RS17060"
                     /protein_end="246"
                     /protein_start="152"
                     /score="41.5"
                     /tool="antismash"
                     /translation="KVNHLTVTSGLRANLLYSTQYGERSKATKKEVVSSSIKYNEVTQK
                     VFDRAQEPILFSTLIDSIKSEYPNVQEETIKQFVWNLFKNEYLISELRP"
     gene            13344..15158
                     /locus_tag="C6351_RS17065"
                     /old_locus_tag="C6351_17065"
     CDS             13344..15158
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="C6351_RS17065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17065"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_187299003.1"
                     /transl_table=11
                     /translation="MKEMFIATKYWLRTIKLLFEVNWFYMICIIVFAILQGILPVATLL
                     ITQELINTILVSIGKSFDPVLFWFVLLAIVSLVLVLVQIIQGYLQSVLQILIVYKLNVK
                     LMKKSSELSLTDFENPEIYDKLQRAQGEVGTRPFQVFTTLLSIITGIITLLSSAVVLIT
                     WKWWVFLLLIITPIISTYYSLKIGKWEFDIQVQRTPKFRKSWYYSFLLTKDINYKEIKA
                     FNLGEYIVNRYKKIYDDFIVMDKKIARRKAVVGLIFSCLEEIIGLFITLFIIFVTFTGE
                     ILIGNLMGYMKAVGLCVTSFKGVFNSIATLLQNNLYIKQFFEFLDLETDMSVGKQDDYI
                     ELGDIKKIEFQNVSFKYPGTQKYALKNVSFTIKKGQIIGIVGENGSGKSTLTKLLLRLY
                     RVEEGTILINDQDINKYSEEDVRKRMSVVFQDYVKYELTVQDNIGLGNVKSLQNKERIL
                     QSAEKSGAKSMIEQFPEGINTQLGSWFAESQQLSGGQWQKIAVARSFFKPADIYILDEP
                     SAVLDPISEKHIFDKFFNVVEDKIGIFTSHRFSTIKIANEILVFDKGSLVEKGSHNQLV
                     EQNGYYSKLYGIQASPFNEENKKSYQMN"
     gene            15190..16572
                     /locus_tag="C6351_RS17070"
                     /old_locus_tag="C6351_17070"
     CDS             15190..16572
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="C6351_RS17070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17070"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_106081853.1"
                     /sec_met_domain="LANC_like (E-value: 9.5e-75, bitscore:
                     245.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKVDEREYISPLGDSEIKFEIERVILEITNRLKNPESVKGIVT
                     NKNNTMKFLEKDIIPWEEVSLSTGYPSICLFLGELSENYPTEKWDVVAHNYVLQINEYL
                     SKNGMYSYSLFQGFTGVGFAVTALSKGATRYQNFIRQTNDLVIDYINRILPTYYKKLEE
                     NNLGMSDYDVISGITGIGRYLLLYKENEREQVALKHILKFLVKMTENKLINNCLAPGWY
                     ISSENQYLDSEKELYPNGNFNLGLSHGIPGPLSLLSVSLKNGIEVEGQKEAIVKIADWL
                     IKFKIESETGSFWSFRVDWDEFIAGEGKQNSASRAAWCYGTPGVARALYLAGKVTNNQE
                     YIDVSIQTLDDLFNYQRHEWGLYSPTFCHGYAGLLHILNLMYIDTKKEKFKGYILELLQ
                     MILNTYDANSPFGFYNYQLGKDKMELSVNIGLIEGVSGILLVLLALIKPIKTDWDTAFL
                     LN"
     gene            16782..18197
                     /locus_tag="C6351_RS17075"
                     /old_locus_tag="C6351_17075"
     CDS             16782..18197
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720068.1"
                     /locus_tag="C6351_RS17075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17075"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_106081854.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.6e-47, bitscore:
                     155.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIFLIAIFFAIIGSSFVQGSTTFAQADNHIYYTVLLKEGDNT
                     DNFINNLKQNNNIVDITYTVPEIGLIQIQADKKKIEEIKQDPLVEEVNQSIGIVNSRQI
                     SNDVTKLQMEPNKPSVWDLQWDVREVTHDGKSYEEFTGTHNVVVGIIDSGIDVNHPDLA
                     KNILSGSKNLVPKGGYRGMEESETGDINYLDDKRGHGTHTAGLIAANGLMKGVAPGIGV
                     RAYRVFGGKSAEPIWIAKAIIEAAKDDVDVINLSLGSYLVDGTIYSKEGASKKEAAEIK
                     AYKKAIKYAKKQGSVVVAAAGNDGIDVTNYQMMDKLIKERLLQDDLTYKGMGLDVPASL
                     SNVITVGSTGPTQELSLFSNYGLGFSDLTAPGGDLRLFNKFGSDAYMKEGWFRKEQVIS
                     TRPRGGYYYGAGTSTAAPKVSGALALIIDKYKFKNSPNEATRELYKYGVNKTPLDALFF
                     GKGKLDIYNAINH"
     gene            complement(18325..19110)
                     /locus_tag="C6351_RS17080"
                     /old_locus_tag="C6351_17080"
     CDS             complement(18325..19110)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C6351_RS17080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C6351_17080"
                     /product="hypothetical protein"
                     /protein_id="WP_000733766.1"
                     /transl_table=11
                     /translation="MKKLISAEIQRIFARKSTIVLFLISILYPLMFFYLSQLRWNFDSY
                     VVNGIKLPLNNLNFPVGQILTYHILLIIIILPLFYSESLSSEVDSGAYKMILLRPFKKW
                     KTLVSKWISLIIVYAGMLLLTYLTNTLIGYVFMPKVEQANYYNIEEPMGLFASSIYNLK
                     FYFIIFIVHIALLSVVSFISVILRKPLLTFMGSIAFIVASIYLFDSIKNILFHTPDIAF
                     SILGGAYNFDYTFVVFILIIPLFFGTSLFIWHKRIGSMV"
     gene            complement(19256..20083)
                     /locus_tag="C6351_RS17085"
                     /old_locus_tag="C6351_17085"
     CDS             complement(19256..20083)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C6351_RS17085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C6351_17085"
                     /product="hypothetical protein"
                     /protein_id="WP_000477082.1"
                     /transl_table=11
                     /translation="MFKSLLLYESEKFWSKKINIICFIAIPIIVLLSLKFAVQTNATLK
                     PLSVAFSSNLNFHLTSLQEMLFTAFNAIVITFCAISFHEEYKKGALRIPFTRGISLKQL
                     YLAKSLIFMLNIFLILILQLLVSLIIGWLFLPKLTKIPLFFMNGLYGIEEIVQYSFKYY
                     LLGYMSLLAFGSIVEFISLKLKTITGVIGLSLGFIFANLLYIIVISPIIKEYPENHPVV
                     FTYQSLSPILTQVKGAAYFAAGVTNIFLYSPIVIFIVFKTLSYITFTRNDYLD"
     gene            complement(20145..20873)
                     /locus_tag="C6351_RS17090"
                     /old_locus_tag="C6351_17090"
     CDS             complement(20145..20873)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002192338.1"
                     /locus_tag="C6351_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17090"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_000717865.1"
                     /transl_table=11
                     /translation="MKKIEVKHVNKTLNKRKIIHDATFDVLEGDICGFIGPNGAGKTTL
                     MKIITGLIRPDEGNVYTNGIDVLQNRELALNGIGAIIEIPVFFEYMSGRKNLQNLARLN
                     PNMNRKEQLAKVEEVLEIVDLKDRGNDKVKGYSLGMKQRLGIAQALLNNPTIVVLDEPA
                     NGLDPMGMRDLRELILNLRKKLGITFFISSHLLDELQKICNKYVFIREGKIKWTGDSHV
                     LMSSVGNEKKLEDVFMELMS"
     gene            21229..21912
                     /locus_tag="C6351_RS17095"
                     /old_locus_tag="C6351_17095"
     CDS             21229..21912
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376128.1"
                     /locus_tag="C6351_RS17095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17095"
                     /product="response regulator transcription factor"
                     /protein_id="WP_078994290.1"
                     /transl_table=11
                     /translation="MDRRVLIVDDNIEIISFVKPALEVEGYTVDYAVSGDQALQKINSD
                     FDIILLDVMLPDTSGFDICKKVRSRVNCPILFLTARGLEQERIKGFLVGGDDYIVKPFS
                     LKELILRMSVHLRKDKRDSSLKKSNELVFGDLRVNILSKSIQINTQLVELTRKEYEIIE
                     LLCTHPGQVFSKEQIFESVWGNISDSNITTVTEHVRRIRLKLHDCGLKNECIKTIWGLG
                     YKWEC"
     gene            21900..23375
                     /locus_tag="C6351_RS17100"
                     /old_locus_tag="C6351_17100"
     CDS             21900..23375
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525615.1"
                     /locus_tag="C6351_RS17100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17100"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_078994289.1"
                     /transl_table=11
                     /translation="MGMLKRLNMHLKIKTQFVLYFLLCFIVSVIMTLLFLGIALFVFEN
                     KKVANAIENYAVINSDKILNVNFQDELNKQIPKDDIEYWIVSNNKKVLYTSAKIKKLPE
                     DLTISSKEYYGKEYNNATYGISFKPFFSEGKFQGGIVLRYKSNIFVESSIINTLLKKIN
                     YNVFFFFFILFPIFVICPFIIILIFSVLFSKDIIRPLKEMIKLSNHIKNGRLDFIIDTS
                     YTNELGQVLKSFEDMRITLQKSLKAQWMMEEQRKDMILSLTHDIKTPITIINGHLELLA
                     GSYNHISEENRKTYINIMLSNSEKIKKMINELNEIWDLERPNFTLNIQKVDLNDYILEL
                     EGDYIYICAKKNVNFRIISSLSPGGKFDFDSFRINEVLQNIITNSLKHTEDNGEIILEI
                     YLENSNLIFRVSDNGKGFNEEVDLVFNKYYKGNGDLIYKNSSGLGLYICKLIIEKHGGE
                     ISAYNNKREGATIEFSLPGKNKLIEDDECSDIV"
     gene            complement(23476..>23712)
                     /locus_tag="C6351_RS32915"
                     /old_locus_tag="C6351_17105"
                     /pseudo=""
     CDS             complement(23476..>23712)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016090861.1"
                     /locus_tag="C6351_RS32915"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="C6351_17105"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="IQSRAKWYGKQVSVVSTFALNQLCYCCPYQNKDIKNLNLLK"
     gene            23939..24346
                     /locus_tag="C6351_RS17110"
                     /old_locus_tag="C6351_17110"
     CDS             23939..24346
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016136174.1"
                     /locus_tag="C6351_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17110"
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_000577230.1"
                     /transl_table=11
                     /translation="MIFQSMITAIIEKLQETVNPYWIIVFGSTVENREREDSDIDIAYL
                     SDTTLGNYERFLLAQELANIVHRDVDLVDLSEASTVFQAQIIHTGKTIFCSDEERKIIF
                     EMKTLKMYSKLNEERKIVFDDIKKRGSIYEE"
     misc_feature    complement(23967..23983)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 25.92"
                     /tool="antismash"
     gene            24336..24749
                     /locus_tag="C6351_RS17115"
                     /old_locus_tag="C6351_17115"
     CDS             24336..24749
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002175020.1"
                     /locus_tag="C6351_RS17115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17115"
                     /product="DUF86 domain-containing protein"
                     /protein_id="WP_000787545.1"
                     /transl_table=11
                     /translation="MKNEVILNKISTIERCIKRIQDVYGNDPENLEDYTKQDSIILNIQ
                     RACEASIDLAMHIVAGKKLGLPQSSREAFDLLVTAGLLSAELANKLKAMVGFRNIAVHD
                     YQSVNLDIVRQIIEKHLTDFKLFTKEVMGILEF"
     gene            25167..25577
                     /locus_tag="C6351_RS17120"
                     /old_locus_tag="C6351_17120"
     CDS             25167..25577
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016083130.1"
                     /locus_tag="C6351_RS17120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_17120"
                     /product="hypothetical protein"
                     /protein_id="WP_000592191.1"
                     /transl_table=11
                     /translation="MIKKLIISSIALGATIGVSKPTFAATIHSPSQFKETRNVHVQSLY
                     SPWQYLGQTSRELQIKSKDPKVLAFELAKEAPFYEEELVDICSEILDANVDVVYWTSKE
                     WVRFEEGNYEFKHEIKIFRDKERQQLITTLES"
ORIGIN
        1 tggtatttta gataattacg gtgataagat tcttctgtta ctggtaccgc aaacttctgc
       61 ttcaataatg catgcacatt tttaaacatc tttttaatgt tacgaagaga gtacatagaa
      121 taatgtaggc cgaaattaaa gatagcttgc tcacggtcac tatttctctc ttttggtata
      181 tgctgcgcaa taagagggta gataccttct tttgctgctg tatcgagaat ttgatattga
      241 gatgtttgat gcaatagttt cttcaacgta tatacaatct tcgttggata tccttctttt
      301 cgatcaacca tgtcacgtag tccgcgaatg acactgcgaa tttgacgatg acaagtatgc
      361 tttaatacat gaatgaattt attcatgtct gcagacaatt caccgatatt catctcttgt
      421 aggactgctt cgataaattt cgcttttcga gcataggtag cttttggtgt aaatggatcc
      481 ctatgttgtt cttctccagc ttctttcgaa cataagaagt ctgaatggat agacagatat
      541 aatgtcgtat atcgttttgt atgctttaca cctttttgca ttttgcaaat tttgaatagg
      601 ggattccccg tacatggtaa tacagttgtt aattcctcga taaccgcacg gatctgatgc
      661 ggatattttt tatgtaagaa acgatacatc ccaccgaagt gagttttgtt tcctctttcg
      721 tcctgcttgt ccaaagaacg ctttaatgtt gtttccgtat gttgttgcat tgcgatgtct
      781 aagaatagtt tcttagctgc tacagatagc ttaaagaaat cctttgtaaa tacaacaggg
      841 ctaatatata cgtacggatt tgctttttct gtttcctcat tcataaaatg agtgagtttg
      901 attgtataac ggccatctac tccattttcg atggagataa tgttatgtaa gtttaatttc
      961 tttaatgcga tatagaattg agagtgttgg atataagcaa attcttcttt atattgcttg
     1021 taatcttccc acatcatatg tattgttaca tttggaatga caccgtttgt atagcatttt
     1081 ttatgtaagt acaagaacac ttcaagatca gcattcgtaa tgccgtataa tttatgcttt
     1141 cttccagttt tttctgcaag tgtagacatt gcgcgacgtg aaaaagatgg tttagctttt
     1201 tcgacaaagc cttctacgtc agcaatgcga tcttcgtatg tcatgtgctg cagaatatct
     1261 tccaaatatg tatctttata gctgtagtat ttctcctcaa atgtttccac aaatttttgc
     1321 caagatttta tggttactag cacagcattg gttgtttccc catttaagct acgttgatta
     1381 cgtatcacaa atgatttccc catctttttc acctccgttc tacaaattca gaaagatatg
     1441 ccaaaatact ataaaatata ccaattttga ttatagcaaa tcgaaaaatg atgaaagctg
     1501 ctcctttaag aagaaaaata gcaacttgca acagcttatg aagctagtgg tatcaaggga
     1561 taagaggatt tcatgatttt tttttgtgtt aaggataccg caaacgtgtt gcaagttgtg
     1621 tggtatgtat aaaagtaagt gaaaaggcac ctaaaccctt ggtatataaa ggattagagt
     1681 gaaaatggca gagaagttag ggaaaggata ccgcaaacat gttgcaagtt agtgaatgca
     1741 atcattaaaa ataaattgta ataattagcc ttgatataaa aggacttgtt ggcatttata
     1801 gaatgaaagt agggaaagga taccgcaaac agtgttgcat cttgtgagaa aaataagggc
     1861 atgcataccg caaacgtgtt gcaagttggg taatatgtat aaaagtaaat agaaaagtac
     1921 ctaaaccctt ggtatataag ggattacagt aaaaatggta gagaagttag ggaaaggata
     1981 ccgcaaacat gttgcatatt atgtatgtaa cttattaaaa atatgagata aatagcttaa
     2041 aaactttaaa atgacatgat tttttttaaa attatttggt tgagaaataa attatactgt
     2101 tgcaagttga aagaaatagg gaaaggatac cgcaaacatg ttgcaagttg attaaaaata
     2161 ggtaagagaa agagcaaccg tgttgcaagt tgaagaatta aggaaagaaa ggtgcaaaaa
     2221 aaatgcagga agtagaaata gggaaaagaa agagcagcat gttgcaagtt gagaaaaata
     2281 aggcaaacaa agcgcaaaag gaatgtaagt aaggggaaat aggtaagaga aagagcaaac
     2341 tgttgcaagt tgaagagtta aggaaagaaa ggcgcaaaag aaatgcaagt aagtagaaat
     2401 aggtaagaga aagagcaaac tgttgcaagt tgaagagtta aggaaagaaa ggcgcaaaag
     2461 aaatgcaagt aagtagaaat aggtaagaga aagagcaaac tgttgcaagt tgaagagtta
     2521 aggaaagaaa ggcgcaaaag aaatgcaagt aagtagaaat aggtaagaga aagagcaaac
     2581 tgttgcaagt tgaagagtta aggaaagaaa ggcgcaaaag aaatgcaagt aagtagaaat
     2641 aggtaaaaga aagagcagca tgttgcaagt taaagagtta aggaaagcaa agcgcaaaaa
     2701 gaatgtaagt aagggaaaag aggtaagagg aagaacaacc tgttgcaagt tgaggagtta
     2761 aggagagcaa agcgcaaaag aaatatagta agtagaaata ggtaaaagaa agagcagcat
     2821 gttgcaagtt gaagagttaa ggaaagaaag gtgcaaaaga aatatagtaa gtagaaatag
     2881 gtaaaagaaa gagcagcatg ttgcaagttg aagagttaag gaaagaaagg cgcaaaagaa
     2941 atgcaagtaa gtagaaatag gtaaaagaaa gagcaaccgt gttgcaagtt aaagagttaa
     3001 ggaaagcaaa gcgcaaaaag tgtgcaagtt gaaagaaata ggtaagagaa agagcaaccg
     3061 tgttgcaagt tgaagagtta aggcaaacaa agcgcaaaag gaatgtaagt aaggggaaat
     3121 aggtaaaagg aagagcaaac tgttgcagtt gagaaaaata aggaaagcaa agcgcaaaag
     3181 gaatgtaagt aagtagaatt aggtaagagg aagagcaaac tgttgcaagt tgaggagtta
     3241 aggaaataaa tgtaagaaaa gaaagaaaca aaaatttgta aatatctgtt acaataaatt
     3301 aaatataata gtagttaaga tttttatact aagaattatt ttattgtgat ccatggttta
     3361 gggaggaaaa gaaagtggat aacttattac aaatgtttcg agatgcattg ctaatctctg
     3421 agccaattta taaaactaac gagctagtat ggaataagtg gaatgcatac tttaaagatg
     3481 ttgaaaataa taataataaa gtactcacat caccccatgc ttctccatca tttactgcat
     3541 tagtatcttg gttagagaaa aagcaagagt ccggaattac attattacaa atttatgcga
     3601 aaattgactc ttataaagaa gaaatatata aagaaattga agtatttata gaaaaagaat
     3661 ttcaaaatgt agtacataca aattctttaa tattagaaaa tgatcaaaat atagataagc
     3721 caaatatagt gaatcacgag gattattacg aggtaaataa ctctgctgtt tattataaat
     3781 taagagatgg gattgcaaag aatcaatttg aagaagatga aataagtaag gtcttacaat
     3841 atcccattga aacgaggtct tctaatggtg tagctcaact ttcttcacac aaagatgaag
     3901 atttaagact taccaatata gaagaagcag ctcgatggaa tacccttgta gatgacgtaa
     3961 tgagtaatat ggatgattta acggcagatt gcttagatgc aatcacaata cagtggatta
     4021 atgaagcaaa atctccagat gattttattg atttttctta tgaacaagtt ttagagatgt
     4081 gcaatattcc aaaaacagtt gttaaaaata aagaatacta tagagcggaa gataaaatta
     4141 agatagcaaa gagaattgca gctttagcaa gcatttttat ctatttaaat gatgagaatg
     4201 aagtcgttgt attaaatgac cgtgatgatg atggggaacg tttagaatta aagcgtgaag
     4261 ttatcaaaag attatttgta ttagattcag ttgttttatg gagacatagt gttactaacg
     4321 aatacatggg cattgaatct tgtcgtatta agccgggtag ctttttaact aattatttgt
     4381 atggatcaaa taatacaaca gccctattat ctaaaaaagc acttgaatac aatagttata
     4441 gacataaata ccataaaagg ttaattcgat acttaacatg gcaatggaga attagacaaa
     4501 tgtattcatc attgaaaaag ccatattcta taggagggga caaggggtta ctctcagtaa
     4561 tggatattcc gaaagattgg aagccaaatc gcattagaga acagttagaa aacgttctaa
     4621 tggatttaga aaatgaaaaa gtaatctctc attgggagta tagtgatcca ctggatgaac
     4681 aacaaattgg gaaacgtaat tggtttaaaa attattacac taacttagga ataacgattt
     4741 taccacctga agaaatgcta cagtcaatgg atagggtaat aggaaagaag attgtagagg
     4801 aaccacaaga gcaattaccg gaagtaacag ttgttaaaga gataaagaag actgtagaat
     4861 cagtcgaaca aatagagaaa aagatccgtg accaaatact gaaagtacac aatgaaaaaa
     4921 aggtaagcat tcgtgaaata gcagatgaaa tgagtatttc tccgtctaca ttatctaggt
     4981 tttgtaatta taaaacaaaa cgtttatcta aaaaagcatt agaaaagcta acaaaatggt
     5041 gtgaaagaca agaaatatta gaaaagatgt aacatagact aaatatttct tttaataata
     5101 gttaaattaa aaatacacat acattatgta tgtgtatttt acttattact accaataata
     5161 gtctgaatgt tctttattaa tggtggtttt ggagggataa gatcctactg gaaagtcatt
     5221 atagttatgc tgcttaatcc actgcaatta aatttcttgt cttatcgata tggttcagta
     5281 acatacgata ctcttcctca tacatagcta tacgttgtag aagagattga ttctctgttt
     5341 ctaaatcttc aatttgattt tgtaactctg tcaattcatt cacatcttta taattttgta
     5401 gaaagagaat aatatcatct aatgtaatag acaaagagtt tttttctttt tctgatgggg
     5461 agaggggaat gttgtttccc atttttcggt cttgttttgc ttgttgtatt tcttcttggt
     5521 attgttttct cacatatgaa ttccaacgaa atccacaagc tgcgggtgtt ctagctagta
     5581 gttttgctac ttctttgaat gcagctaact gtgtgccacc gttacgaata ttctgaagta
     5641 ctgttgatgc gagaagtaaa tcgttatcat cagtccagga atcttgtctt gagattacca
     5701 cgttttaacc ccccttatat gttttatatt atatatatgc aattactcaa aatgatagaa
     5761 gttcaacttc tcttgaaata attgggagta atttggtaaa agtatgtatg attttaaatg
     5821 caaaattgca tttaaggttg actatttcgt aaaggtgtaa ctataatggt tacagttatg
     5881 taactgaatt aataaagttg ttggtatgaa ttggttgtat taatgatgta taaacaaata
     5941 ttaaagaatg aatggagttg aaaatatagt cctacatata aaacgtttgt ataaaaagaa
     6001 attagataat atacattttt ttataattat atattaataa aaagaggtgc acgttttgaa
     6061 aatttttaag ggaattctag tttcttcaat tgcattaaca gcatttaatg gggtgggtgg
     6121 actacttcca agtgaaaaat cagaagttgc ctatgcagct acctacaatt atacaaataa
     6181 gcaattgaat tctactgtac ataagcaagt tactaaacaa ttaattttga aatttaaaaa
     6241 tgaagcgaat ttaccatatc aggatggaat tgaaaaattc attaaagaag aaaaacaaga
     6301 tcctgaatta attggaattt tagctgaata tccaaatgta actataaatc gactttttaa
     6361 ttctttaaat cctaaagaaa ttaaaaatct tggtaaagaa ataaaagatt ccgatcatat
     6421 ttcttctaat ttgctaaact attatattgt agaaactcaa gatgatattg atgtacaagc
     6481 attacttaca aaaattgaaa aatcatcact tgttgaaacg gcgtatttac aggaagaaga
     6541 ggcgccacca gcagagcgtt tgccaaattt atctgttaat ccatatgatg agcctagact
     6601 tacaagacaa ggttaccttg aaccagcacc attaggaatt aatgcacctt atgcctggag
     6661 cataaaaggt ggggatggaa aaggaactac tttcgtagat atggagtatg ggtggttatt
     6721 tagtcatgag gatttagtga atcaaaagat tgaattgata tctggacaga ataaaagcga
     6781 gcaccatgat catggtacct cagtcttagg cattgtttcg gcagaggata ataacatagg
     6841 tggaattggg atcgcaccga aagctaaggt aaaggttgta tcccagatta gggataacgg
     6901 aaattataat acagctgatg ctattttaag tgcggttaac aatatgcaag ctggagatat
     6961 tcttttacta gaggcacaag caacttacga tggatatgga gataagaact attttcctgt
     7021 ggaagtaaaa ccagacatat ttgatgcaat tcgtatggga acaaataagg gaattattat
     7081 tattgaagca ggtgcaaacg gcggaaatga tttggatcaa tttagagacc gtaatggtaa
     7141 acaagtttta aatcgtaata gtcctgattt taaagattca ggagcaatta tggttggggc
     7201 agcttctgca agggttcctc ataagcgttc atatttctct aattatggta gtagagtgga
     7261 tgtatatgga tgggggaatg cagtagatac tacagatgct aaaccaagtg aatttataac
     7321 aaatctatat acatctagtt ttgctggaac atctagtgca tcgcctatta ttgctggtgc
     7381 tgcagcatca attcaaggaa tagcaaaaaa taatcaggga aaagtatata caccaagcca
     7441 gattagggct attttaagtg accctagtac tggaacgaaa tctaacgatc caatctctga
     7501 taaaattggt gttttacctg acttaaaagc cattttatct aaacttggtt tttcaccaaa
     7561 cttaggtaat gattcttcca ttgtatttcc tgaggaacaa gaaataaata aaggaaataa
     7621 gggaaatgaa ggatctacta ttacattccc gaaagaagat accgctaata gtgaagagga
     7681 ctctagcttt attttcccag aataattgta gggataattt ctatttaata taaagaaatt
     7741 ttatataact agttaagtat aatactaatg aggtaggctc ttatgtgtaa gatcataagg
     7801 gcctatttgt tgtactttta acaatatagg aggggagtaa ctctttagat atttaccctg
     7861 cttaacaaat caagcattac aatggacata gtaaattcgt acttgtgggt atttttattt
     7921 gttaagttaa tgatcgatcg atgcggtaga atcccttatt ttaaaataaa ttagataaca
     7981 aagatatgga gaattaattt taaaatgtta tattttcatg gaatctatta ctttgtaaac
     8041 ttccgccatt tatgtttttt atattttaat ttgtttgatc tgcattactt tttatagcca
     8101 tattaaactt tgatgaatgg tatttatata tattcataga atggaattag aatattgttt
     8161 actgggaaaa ttaagaataa atagggacga aaccttatta catcctgtta cggatggtaa
     8221 gtatgtaatg cttgttgaat aatcagtaaa taaaatttgt ttttgggata gaatcatgag
     8281 gaagcactct tttttcttcg aatgggattt agatatgagg atatttagtg aagagtattt
     8341 aatttatatt tgtaagaaaa aaagttaatc tatgaagatt ataggataaa tctaacttta
     8401 taaattcctt tatgaaagcg taaagtaagt ttatgtaaaa acttaaatta tattagaatt
     8461 gcattttgta ttgtttttca cgagtttaaa tagtgtattc aaaaataatt tgtaggcaat
     8521 aaagaagata gtaaatatag gaaagtagga tgtaattata tatataaatt agatagtgtt
     8581 attaattttt tcagtaaaat tcatatataa atatttcaat tttttttaac ttatatgcat
     8641 tttcttcaaa taaattcaaa atcttgacat ttattgggtt tctggtaaga taaaaaagct
     8701 aattatgtga ataaattaag tttttactta tttaaaagtt aatatgcctt aacctcaagt
     8761 ttatgttgtt ttaacggtaa tactatattt aattagatta aatatttttt gtatatattt
     8821 aattttaaat atgtatattt acataataag tatgaaaagt atttttttta cattatctat
     8881 tgacaatcca aaatatgggt ataaaatgaa atatagataa ggaggtgaga aaaaatggaa
     8941 aacaatttgt ttgatttgga tttaaaagta gaaaaatcat caaatggtgt tgagccaaga
     9001 gtgacaagtt atgcgttctg tacaccaggg acatgtgcat gtgaagatgg tccaacattt
     9061 gattcagcat gttgtagtgt agagttaact atttacaact gcaagtaaga aagaatgtaa
     9121 aaagtattta ttagaaaaat agatactagt aattacataa tatatttttg acaagggttc
     9181 acattaaata attagaattt ttgtataaaa atatatagtg gaggtgagaa aaaatggaaa
     9241 acaatttgtt tgatttggat ttaaaagtag aaaaatcatc aaatggtgtt gagccaaggg
     9301 tgacaagtta tgcgttctgt acaccgggga catgtgcatg tgaagatggt ccaacatttg
     9361 attcagcatg ttgtagtgta gagttaacta tttacaactg taaataagag taataaattg
     9421 cattcgtaaa tatctgataa gtagtaaaag taataatatt attaatcttt aatctcgtta
     9481 aattaattaa gtggttacat ttaattctaa aaatcaattt ataacaatta tatggaggta
     9541 aagaaaatgg aaaacaattt atttgattta gacttaaaag tagaaaaatc atcaaatggt
     9601 gttgagccaa gggtgacaag ttatgcgttc tgtacaccgg ggacatgtgc atgtaaagag
     9661 ggtccaacat ttgattcagc atgttgcagt gttgaactta cagtttacta ttgtacaaga
     9721 taaataataa atacgatttt ctgtatccta atgttcattt taaatgaaca ttaggataca
     9781 aaattagaaa ttaatgtatg tagtctacat tttaaataat ctcagagtaa atgagattta
     9841 gggtgttttt aaggtaagtt tatttataat attataagtt tgaagatggt agtaaacgat
     9901 atgtttaaaa aatttgagga atggaaaaac cgtttctcaa attttttaaa taaaagttta
     9961 tagtgcgaca atacataaat atagggggat taagagaaga atgaaatatt tatatacacc
    10021 attagatttt tttctgttac gtacacccac atatccaatt gataatttta aaagtattat
    10081 agatatcgaa agtgaagagg aaattttaga ttatatatta aataatgttc ttagtaatga
    10141 aaaaataatt gaaatgctta tagtggcaag tccgaaatta tatgaggcgc ttctaagatt
    10201 ggaaaataat cccgatacta aaaagaaaga acaaattatt ctcaacttaa ctaaatattt
    10261 aataagaatg agtactagat caacaccgtt tggtctattt tctggtgtct cgatgggtga
    10321 ttttgatgat aaaacggata ttcaaataga tgatataaat cattttacta agacagcccg
    10381 ccctgatatg gcatggttat taggctgtat aaaacaaatt gagtcggata ttgaaaatgt
    10441 taaatgttta aaggtcaagg taaatcatct tactgtgact tctggattaa gagcaaattt
    10501 attatatagt acgcagtatg gagaaagatc taaggcaacc aaaaaggaag tagtatcatc
    10561 ttctattaaa tataatgaag ttactcaaaa ggtttttgac agagcacagg aacctatatt
    10621 attttctacc ttaatagata gtattaaatc agaatatccg aatgttcagg aggaaactat
    10681 aaaacaattt gtatggaatt tgtttaaaaa tgaatattta ataagtgaac tccgacctat
    10741 tttaacaaat ggaaatccct ttgagtatgt cattaataaa ttatctgaaa aagaagcact
    10801 taccaaatat tatgtacaac taactaagtt aaaagaagat atagatatat ataatggatt
    10861 atctttggga gaaggaaagg aattactgtt aaatctattt gataaaatga gggaaatata
    10921 tgaagtagat acccctttac aagtagatct atcaataaaa acaaaacata gtactataag
    10981 taagtctatt caaaatgaac tatcaaaagt agcagatttt ctttgggtcc ttacccctaa
    11041 agaaaatatt aataatgagt tagatcatta tcgaaatgat ttcttagaga aatatggaga
    11101 atatagggaa atttctatac tagagctcct taatcctgat attggacttg gagcacctgg
    11161 aggatacctc aatccaccta gttataaaaa agtagaaaat ccacctgtaa atcaattaaa
    11221 cgaatttgaa aattatcttt tagaggaaat atctaaatta ttatgtagta ataatggaga
    11281 tattcgagag attaatatag aaaataaaat ttatgaaaaa tttaaaaaga aagacatgga
    11341 tttaaataca gctgctgttt caatggaatt atattttaga attatttcag aaagtttttc
    11401 taatatagat aatgaggaat atcaaataca gttagtacct aacgcagggt ctgatggagc
    11461 aggtaaaacc tttggaaggt ttaatcaaat gcttaatgaa gaaaatcagg aaaaaataaa
    11521 taaaattaat caattagaaa aatcatttta tgaagataca atatttgcag aaatggttta
    11581 tttaccagat tatggacgtt ctgcgaatgt tactattagt aacagtataa gggattatga
    11641 gttgtgtatt ggtacaaatt cttcaaaaga caaaaagcac acattaagta tgtctgattt
    11701 agtagttgga gtatatcagg ggaatttcta tatacgatca aaatctctta acaagcgagt
    11761 tattattact acaggtcaca tgctaaacat cgcaggatgt cataatcttt gtagactgct
    11821 aaaagaactc tcaaaccatg ggatggtgca ttggaagtta ccaattttta gttggatgac
    11881 aaagatggca tttgttccaa gaatcaattt agggaaagtt acaattatac ctgcaatgtg
    11941 gaatttaaat ttaaatatgt tagacattaa tgtgaaagaa ctaaaaaagg atttcgaact
    12001 ttttaaaaag cagttccata agtggtgtga agaatataat gtacctagat atatttatct
    12061 gtttgatatg gataatagaa ttttaataga tacaaaaaat aatctacacg taaaaataat
    12121 tcaaaaagaa atgtcttcct caaaaggcaa taaggttcaa ttttatgaga tgggaaatga
    12181 aatttgtaaa gaatggatag aaggggacac tggcacgtat atctctgaag tagtagtgcc
    12241 atttgttaaa aactcagaag tagtagaaga aaaaatgaaa gttcatttta atgcgagtca
    12301 tagcatcgaa tgcgatcaag ttagaactaa ggcactaggt agtgattggc tatattttag
    12361 aatttattgt aataataaca tggaagatga gtttattggg cgagaattac aattaatttg
    12421 taataatgcg gtttctgagg gactagcaga taagtatttc tttatgagat attctgataa
    12481 taaaaaacat ataagattaa gatttaatat gttaaacaaa gataattttc caaaacttat
    12541 ctcctatatt aatacacatt gcaatcaatt aaaagcaaag ggaattgtat caaacgtagc
    12601 tattgatgtg tatgaaagag aagtagaaag atacggagga ccagagctta taggagaagc
    12661 ggaagattta ttcttccttg atagtcaatt tgtacaggag ttaataagac taaaagaaaa
    12721 taatttactt aatactagtt ttgaaaacat ttgtatttat agtatattgg attatttgca
    12781 aggatttgga ttaactcatg aggaacaatt aaagctcatg gaggctgttg tggattataa
    12841 ggaatattta gaggatttca gaaaaggaaa aaaagtatta gtgaatctgt gtaataaaaa
    12901 taatgttatt gattttggaa ttacaacaga taattcaaac ttatatgagt tgttagcggc
    12961 taggaaaaaa cagattaaat tatataaaga aaagatagat gatgtagaaa tacaaggaaa
    13021 attatttaat gtaagagaaa atattatact tagtgtaata cacttacatt gtaatagatt
    13081 aataggtata gacagagttt atgaaaaaaa attaaataca ttagcaagac ataccttaaa
    13141 ggctctaagt tatttttatg agcaacaaaa taaaattttg ataacacact aatcgaataa
    13201 taaatttaag gacagaacgc aattattata ataattgcgt tctgtcctta aaaacaattc
    13261 ggtttttaga aaatatacat aacagtatta taagctaaga tatataatcc aaattcatga
    13321 tgaggaagaa tataggtgag aaaatgaaag aaatgtttat agctacgaaa tattggctaa
    13381 gaaccataaa gttacttttc gaagtaaact ggttttatat gatttgtata attgttttcg
    13441 cgatattaca aggtatccta cctgttgcca cactcttaat aacacaagaa cttataaata
    13501 caattttagt atctatagga aaaagttttg atccggtatt attttggttt gtattattag
    13561 ctatagtttc attagtacta gtattagttc aaattataca aggttatttg caaagtgttt
    13621 tacagatatt aattgtatat aaattaaatg taaaacttat gaaaaaatca tcagagttat
    13681 cattaacaga ttttgaaaat ccggaaattt atgataaatt gcagcgtgca caaggagagg
    13741 ttggaactag accttttcaa gtattcacta ctcttttaag tataattact ggaattatta
    13801 ctttattatc ctccgctgtt gtactaatta cttggaaatg gtgggtgttt ttacttttaa
    13861 ttataactcc aataatttct acttattatt ccttaaaaat tggtaaatgg gaatttgata
    13921 tacaagtaca aagaacccct aaatttagaa agtcatggta ctattccttt ttattaacaa
    13981 aagacattaa ctataaagaa ataaaagcat ttaaccttgg agaatatatt gttaatagat
    14041 ataaaaaaat ttatgacgac tttatagtaa tggataaaaa aatagctaga agaaaggctg
    14101 tagttggcct aatatttagt tgtcttgaag aaataatagg tctgtttata actttattta
    14161 ttatctttgt cacatttact ggagaaattt taatagggaa tttaatgggg tatatgaagg
    14221 cagttggatt atgtgtaacg agttttaaag gtgtttttaa tagtatagcc acattactac
    14281 agaataattt atacataaaa caattcttcg aatttttaga cttggaaact gatatgtctg
    14341 taggaaaaca agacgactat attgaattgg gggacattaa aaaaattgaa ttccaaaatg
    14401 tttcctttaa atacccaggt actcagaaat atgctttaaa gaatgttagt tttaccataa
    14461 aaaaagggca aattatagga attgttggtg aaaatggttc agggaaatct acacttacaa
    14521 aactactcct aagattatac cgtgttgaag aaggcacaat actgattaat gatcaggata
    14581 taaataaata cagtgaagaa gacgttagaa aaagaatgag tgttgtattt caggattatg
    14641 taaagtatga attaacggtt caagataata ttggattggg gaatgttaag agcctacaaa
    14701 ataaagaacg gatattacaa tcagcagaaa agagtggggc taagagtatg atagaacaat
    14761 tccctgaagg aataaatact caattaggta gttggtttgc agaatctcaa caattatctg
    14821 gaggacagtg gcaaaagata gctgttgctc gttcattttt taagccagca gatatctata
    14881 tattagatga acctagtgct gtacttgatc caatatctga aaaacatatt tttgataaat
    14941 ttttcaatgt tgtggaagat aaaataggaa tctttacgtc acatagattt tctacaatta
    15001 aaattgcaaa tgagattttg gtatttgata aagggagttt agtagaaaag ggtagtcata
    15061 atcagttggt tgaacaaaat ggatattata gcaaattata tggtatacaa gcatctccat
    15121 ttaacgaaga aaataaaaaa agttatcaaa tgaattaaat taaatttaat tttgagaggg
    15181 gtaaggggat tgataaacaa agtagacgaa agggagtata tttctccatt aggggattca
    15241 gaaattaaat ttgaaattga acgcgtcatt ttagaaataa ctaacagatt aaaaaatcca
    15301 gaaagtgtaa agggaattgt aacaaataaa aataatacga tgaaattttt agaaaaggat
    15361 ataattccat gggaagaagt aagtttaagt acaggctatc caagtatatg tttatttctg
    15421 ggtgaattgt cagagaatta tccgacggaa aaatgggatg tagttgctca taactatgtt
    15481 ttgcaaatta atgaatacct atctaaaaac gggatgtatt cgtactcact ttttcaaggg
    15541 tttactggag ttggtttcgc ggttacagcc ttatcaaaag gtgctactcg atatcagaat
    15601 tttattagac agactaatga tctagttata gattatataa ataggatttt acctacatat
    15661 tataagaaat tagaggaaaa taatttagga atgtcagatt atgatgtgat ttctgggata
    15721 acagggattg gacgatactt actgttatat aaagaaaatg aaagagagca agtagcttta
    15781 aagcatatat tgaaattttt agtgaaaatg acagaaaata aactaattaa taattgtttg
    15841 gctccggggt ggtatatttc ttctgaaaat cagtacttgg attcagaaaa ggaattatat
    15901 ccgaatggaa actttaattt aggactatca catggcattc caggtccact gtcattactc
    15961 tctgttagtt taaagaatgg aattgaagta gaagggcaaa aggaagctat tgttaaaatt
    16021 gctgattggc taataaagtt taaaattgaa tcagaaacgg gttccttttg gtcatttagg
    16081 gttgattggg atgaatttat cgctggagaa gggaaacaga atagtgcgtc aagagcagcc
    16141 tggtgttatg gaactccagg agttgcaagg gccttatatc ttgctggaaa ggttacaaat
    16201 aatcaagaat atatagatgt ttctattcaa accttagatg atctttttaa ttatcagaga
    16261 catgaatggg ggctatattc gcctacattc tgccatggat acgctggact tcttcatata
    16321 cttaatttga tgtatattga tacaaaaaaa gaaaaattta aagggtatat tttagagtta
    16381 ctgcaaatga ttctaaatac atacgatgca aattcgcctt ttggttttta taattatcaa
    16441 ttaggcaaag ataagatgga gctttcagta aatatagggc tgattgaggg agttagtggt
    16501 attcttttgg tactattagc attgataaaa cctataaaaa cagattggga tacagcattt
    16561 ttactcaatt agtttaggtg tggatacgta ataatttagt atgctagtta gatgaattta
    16621 tgtaaatgat taatgtagtt tgttcataga agataatagt ttaagtttaa tattaacctt
    16681 aaactattat cttttaatgt tggattagaa ttattaattc gtattatttg tttgaatttt
    16741 tcaagtggga atttctataa aatagttagg gatggttatt aatgaaaaaa ataatttttt
    16801 tgattgctat attttttgcc ataattggaa gttcttttgt tcagggatcg actacttttg
    16861 ctcaggctga taatcatatt tattataccg ttcttttaaa agagggggat aacacagaca
    16921 actttataaa taatttaaaa caaaataata atatagtaga tataacgtat actgttcctg
    16981 agattggact tattcaaatt caggctgaca agaagaaaat agaagaaatc aagcaagatc
    17041 cattagtgga agaagttaac caatcaattg gtattgttaa ctctagacaa atttcaaacg
    17101 atgtaacaaa attgcaaatg gaacctaaca aaccatcagt atgggatttg caatgggatg
    17161 taagggaagt gactcatgat gggaaaagtt atgaagaatt tacaggcact cataatgtag
    17221 tagttggcat tatagattca ggtatagatg ttaatcatcc tgatttggct aaaaatatat
    17281 taagtggatc aaaaaattta gttcccaaag gtggatatag gggaatggaa gaaagtgaaa
    17341 ctggtgatat aaattattta gatgataaac gtggtcacgg cactcataca gcggggctta
    17401 ttgctgcaaa tggtttaatg aaaggggttg ctcctggtat aggagtacga gcttataggg
    17461 tctttggtgg taaatctgct gaaccaatct ggattgccaa ggcaatcata gaagctgcta
    17521 aggatgatgt agatgttatt aacttaagct taggttctta tttagtagat ggtacgattt
    17581 attcaaaaga aggggcatca aaaaaagaag cagctgaaat caaagcatat aaaaaagcaa
    17641 taaaatatgc aaaaaaacaa ggaagcgttg tggttgcagc tgctgggaat gatgggattg
    17701 atgttactaa ttatcaaatg atggataaat taataaaaga aagattatta caagatgatt
    17761 taacatataa aggtatgggt ctagatgttc cggcaagttt atcaaatgtt attactgtag
    17821 gttctacggg tcctacccaa gagttatctt tattttcaaa ttatggattg ggttttagtg
    17881 atttaacagc accaggtgga gatttaagat tatttaacaa attcggtagt gatgcatata
    17941 tgaaagaggg atggtttagg aaagagcagg ttattagtac acgtccaaga ggaggatatt
    18001 actatggggc aggtacttca accgcagctc ccaaagtttc tggcgcgttg gcattaatta
    18061 ttgataagta taaattcaaa aattctccta atgaggcaac tagagaatta tataaatatg
    18121 gagttaataa aactccgcta gatgctttat tttttggaaa aggaaagctg gacatctata
    18181 atgctataaa tcattgattc ttaattatta taagacaaaa taaaagggga ggattgagag
    18241 tgaaaactca tcctactcct tttttatttg taaatataaa agtcctttat tattaagtta
    18301 tcagttggtt caaattgaaa ctatttatac catactgcca attcttttat gccaaatgaa
    18361 taatgatgtt ccaaaaaata agggtataat caagataaat acaacaaagg tataatcaaa
    18421 gttatatgct cctcctaaaa ttgaaaaggc aatatctggg gtgtgaaata gtatattttt
    18481 tattgaatcg aataaataaa tggaggctac tataaatgca atacttccca taaatgtgag
    18541 tagtggtttt cttaagataa cacttataaa tgaaactaca gaaagtaatg caatatgcac
    18601 tataaaaata ataaaataaa attttaaatt atatatactg gaagcaaata aacccatagg
    18661 ttcttctata ttataataat ttgcctgttc taccttaggc ataaagacat atccaatcaa
    18721 agtgtttgtt agatatgtta acaataacat gcctgcatat acaattatta atgaaatcca
    18781 tttacttacg agtgttttcc actttttaaa aggtcgtagt aagatcattt tatatgcacc
    18841 tgaatcaact tctgaactta atgattcaga atagaataaa ggtaaaataa taattattaa
    18901 aagaatatgg tatgtaagaa tttggccaac tggaaaattt aaattattta aaggaagttt
    18961 tattccattt acaacataac tatcaaaatt ccaacgaagt tgacttaaat aaaagaacat
    19021 aagtggatat aaaatagaaa ttaaaaataa aactattgta ctttttctag caaaaatcct
    19081 ttgaatttcg gctgaaatta attttttcat agtatacacc ctctctatat agcattaaat
    19141 aaaatcaata tttactttta aaaaatcata caaataatgc gtaacatatg tgtctgtaga
    19201 gtttgtaggt ttaaaaaata tatttaatac ccttacattt taatttgtta gcgatttaat
    19261 caagataatc gttacgtgta aaagttatat aagataaagt tttaaaaact ataaatataa
    19321 caattggact atataaaaat atatttgtaa cgccagcagc aaaatatgca gcccctttga
    19381 cttgagttaa tattggtgat aaagattggt atgtgaatac aacaggatga ttctctggat
    19441 attctttaat aataggactt attactataa tgtataaaag attagcaaat ataaatccta
    19501 gacttaaacc gataacacct gtaattgttt taagtttcaa ggaaataaac tcaacgatgc
    19561 taccaaaagc aagtaaactc atatacccta ataaataata tttaaaagaa tattgtacga
    19621 tctcttcaat tccataaaga ccattcatga aaaataaagg aattttagtt aacttaggta
    19681 agaataacca acctataatt aatgaaacaa ggagttgtaa aattaggatt agaaaaatat
    19741 ttaacataaa aattaaagat tttgctaagt ataattgttt taatgaaata ccccttgtaa
    19801 aagggattcg tagagcacct tttttatatt cttcatgaaa acttatagca caaaaagtaa
    19861 tgacaattgc attaaaagca gtaaagagca tttcctgtaa acttgttaaa tgaaaattta
    19921 aatttgagct gaatgctacg cttaatggtt tgagtgtagc attcgtttgc acagcaaatt
    19981 tgagagatag taaaacgata ataggtatag caataaaaca tattatatta atttttttag
    20041 accaaaactt ttcagattca tataaaagta aagatttaaa cattgaatcc tcctattact
    20101 catagatata tttttgatta gaatgtgtga ggtttattgg atttttaaga cattaattcc
    20161 ataaagacat cttccagttt cttttcatta cctaccgaac tcattagaac atgactatca
    20221 cctgtccatt taattttgcc ctctctaatg aatacatatt tattgcatat tttttgaagt
    20281 tcatctagaa ggtgactgga aatgaaaaat gtaattccta atttctttct aagattaaga
    20341 attaattctc ttaaatctct cattcccatt gggtcaagac catttgcagg ttcatctaat
    20401 accactattg ttggattatt aagtaatgct tgtgcaatgc caagtctttg tttcataccc
    20461 aaagagtaac cttttacctt atcattgccc ctatctttta aatcgacaat ttctaaaact
    20521 tcttcaacct ttgctaattg ttcttttctg ttcatatttg gatttaatcg tgcaaggttt
    20581 tggagattct ttcttcctga catatattca aaaaatacag gaatttcaat aattgccccg
    20641 attccattta gggctaattc tctattttgt aatacgtcaa taccattagt atatacattg
    20701 ccttcatctg gtcttattaa cccggttatt attttcataa gagtggtttt tccggcacca
    20761 tttggtccaa taaatccgca tatatctcct tctaaaacat caaaagtggc atcatgaatt
    20821 atttttcttt tattaagggt tttattaacg tgcttcactt ctattttttt cattttttat
    20881 ttcctttctt attaagaatt atgacgatat cgtttgattt gaatgggggt aattgttctt
    20941 acacttatat ctaaacatat aaaaaacaac tctttatcaa ctttgtgtat ttttcttatt
    21001 tttagtttta aaaatgaata gtatgaatga ataatttaat gcgattttgc tcaaaagagg
    21061 tatttattgt aaaatctatg tagctattat attaagaata gtaaaatgat taatacttgt
    21121 ataacaatat tttttcatat ttccattaat agatttcgaa tcagagtgaa ggtaagtagg
    21181 gtttataaag agtttatata aagatattaa aaaagggtga tataagaaat ggatagacga
    21241 gtacttatag tcgatgacaa tatagaaata atctcatttg taaaaccagc acttgaagtt
    21301 gaaggatata ctgtagatta tgctgtatca ggggatcaag ctttacaaaa aattaattcg
    21361 gattttgata ttatcctatt ggatgtaatg ttgcctgata cgagtggatt tgatatatgt
    21421 aaaaaagtta gaagtagagt taattgtccg attttatttt taacggctag ggggcttgag
    21481 caggaaagaa tcaaaggttt tttagttggg ggagatgatt atattgtaaa accattttca
    21541 ttaaaagaac ttattctgag aatgagcgta catttaagaa aagataaaag ggattcgtcc
    21601 ttaaaaaaat ctaatgagtt agtcttcggt gaccttagag ttaatatttt atctaaaagt
    21661 attcaaataa atacacaatt ggtagagttg acaagaaaag aatatgaaat tattgagtta
    21721 ttatgtacac accctgggca agtattctct aaagaacaaa tttttgaaag tgtgtggggg
    21781 aatataagtg acagtaatat aactactgtt actgagcatg taagaagaat acgtttaaaa
    21841 cttcatgatt gtggacttaa gaacgagtgt ataaaaacaa tttggggatt gggatataaa
    21901 tgggaatgct aaaacgttta aatatgcatc taaaaataaa aacacagttt gtattgtact
    21961 ttcttttatg ttttatagta tcagttatca tgacattgct atttttaggt atagctttat
    22021 ttgtatttga aaataagaag gttgcaaatg ctattgagaa ttatgcagta attaatagtg
    22081 ataaaatttt aaatgtaaac tttcaagatg aattaaataa acaaattcct aaagatgata
    22141 ttgaatattg gattgtatct aataataaga aggtattata tacttcagca aaaataaaaa
    22201 agttacctga agatcttaca attagttcaa aggagtatta tggtaaagaa tataataatg
    22261 ctacatatgg aatttctttt aaaccttttt ttagcgaagg caaatttcaa ggtggaatag
    22321 ttttaaggta taaaagtaat atttttgtag aatccagtat cataaatact cttttaaaaa
    22381 aaattaacta taatgtattc tttttctttt ttattctttt tcctatattt gtaatttgtc
    22441 cctttattat tatattaatc ttttctgtat tattttcaaa ggatataata cgtcctttaa
    22501 aagaaatgat taaattaagt aatcatataa agaatggccg tttagatttt ataatagaca
    22561 cgtcttatac taatgaatta gggcaagttc taaaatcatt tgaagatatg aggataacac
    22621 tacaaaaatc gctaaaagca caatggatga tggaagagca aagaaaagat atgattttgt
    22681 cacttactca tgatattaag acaccaatta ctataattaa tggacattta gaattactcg
    22741 caggatcgta taatcatatt tcagaggaaa atagaaaaac atatattaat attatgctta
    22801 gtaattctga aaaaataaaa aaaatgatta atgaactaaa tgaaatctgg gacttagaaa
    22861 gaccaaattt cacattaaat atacaaaagg tggatttaaa tgattatatt ttagagcttg
    22921 aaggggatta tatatatata tgtgcaaaaa agaatgttaa tttccgtata atatcttcat
    22981 tatcacctgg gggaaaattt gattttgatt cttttagaat aaatgaggta ctccaaaata
    23041 ttataaccaa ttctttaaag catacagagg ataatggaga aattatactt gaaatatact
    23101 tagagaatag taatttaata tttcgagtgt cagataatgg aaagggattt aatgaagaag
    23161 tcgatttagt ttttaataaa tattataagg gaaatggaga tttaatatat aaaaatagtt
    23221 ctgggctagg actttatatt tgtaagctaa ttattgaaaa acatggagga gaaatctctg
    23281 cgtataataa caaaagagaa ggagctacta ttgagttttc tttacctggc aaaaataagc
    23341 taatagaaga tgatgaatgt agtgatattg tatagaagta tacgattaag aaaagtagaa
    23401 tgattttgtc cgattaatat ttaaagctaa tcagtggtaa ttaatgcgtt ctaataatta
    23461 gatagaagaa agggcttatg ttaaagattg cttaaagata agttctttct ttttttttat
    23521 ttcattcttt agtttgacac ttgtgttaat attctcatca tgatgtgtaa gactagaagg
    23581 acagtttcat ttaaggaggt ttagattttt aatgtctttg ttttgatatg gacaacaata
    23641 acataattgg tttaaagcaa atgtagatac gacactaact tgtttgccgt accattttgc
    23701 tctgctctgt attccaacat ggtccgaaac tataatcctt catggagtag gtgggggaaa
    23761 tgaattggct tcgggcaaga ggtggtagga ggtcatttta attgtttgaa aggtgatcag
    23821 gagttaatta atgaagaggg tgttttaatt ttcttaatgt attataatac atagctgaaa
    23881 aggttatata atggttatga tataataaaa ttcaagtaca ataaggggga ttaattaaat
    23941 gatttttcaa agcatgataa cagctattat agaaaaatta caagagacgg tgaatcccta
    24001 ttggataatt gtgtttggat caacggttga gaatagagaa cgagaagata gcgatattga
    24061 tatagcttat ttaagtgaca caactttagg gaattatgaa cgttttttat tagcacagga
    24121 gttagctaac attgttcata gagatgttga tttggttgat ttatccgaag cttctacagt
    24181 ttttcaagct cagattatac atacaggaaa gacaatattt tgttctgatg aagaacgaaa
    24241 aatcattttt gaaatgaaaa ccttaaaaat gtattcaaaa ttgaatgagg aacgcaagat
    24301 agtattcgat gatataaaga aaagaggttc aatatatgaa gaatgaggtt attttaaata
    24361 aaatttccac aatagagcgt tgtataaaaa gaatccaaga tgtgtatgga aatgaccctg
    24421 aaaatttaga ggattataca aagcaagatt caataatatt aaatatacaa agagcttgtg
    24481 aagcgagtat tgatttagca atgcatattg ttgcagggaa aaaattagga ctacctcaat
    24541 ctagtcgtga agcttttgat ttattggtta cagcagggtt acttagcgca gagctagcaa
    24601 ataagttaaa ggcgatggtt ggatttcgta atattgctgt tcatgattat caaagtgtaa
    24661 atttagatat tgttcgtcaa attattgaaa aacatttaac tgattttaaa ctatttacaa
    24721 aagaagtaat ggggatattg gaattttagg caaaagaaca gaataatagg gctgagaaag
    24781 aaagtaattc tacgattccc aaactaacta ttgaaacaat tacttaattt cgtaagaaga
    24841 aacgcggtca taagatgaat ttgtttatgt tgtagtgagg ctttgcatga gatgtgtgta
    24901 gataatagta ggaacaatat ccatatacaa ttttatcaac aaataagtaa atatttttaa
    24961 aactaatttt tatacatata atgtataccc aaaacaaaaa aagtttccat aaggaaactt
    25021 tttttgtttt gggtaaattt ataacgatta attaatattc agtttttgaa aaaaatgatg
    25081 aatcatgtca aatcatcttc atttacacga acatgaacgt agtataaaaa tgaagcatat
    25141 ccaaaataat taaaggggct gaaaaaatga ttaaaaaact tattattagt tctattgctt
    25201 taggtgcaac aataggagtg agcaaaccta catttgctgc tacaatacat tctccatcac
    25261 agtttaaaga aactcgaaat gttcatgtgc aatccctata ttctccatgg cagtatttag
    25321 ggcaaacttc aagggaactt caaattaaaa gtaaggatcc aaaagtacta gcttttgaac
    25381 tagcaaaaga agcaccattt tacgaagaag aattagtaga catatgttct gaaattttag
    25441 atgcaaatgt agatgttgta tattggacaa gtaaggaatg ggttagattt gaagaaggaa
    25501 attatgaatt taaacatgaa attaaaattt ttagagataa agaacgtcag caattaatta
    25561 cgacactaga atcttagttc ttttacaaaa aagaagctat ctttagtatg ctattctccc
    25621 ctcatagtag ataggaaaaa gaaaacacat taacctattt attatggagg ggatttttct
    25681 atggggtaaa ttagaattac ttgctataca aaatgaaagg caaaggaagt gggtttatac
    25741 ttaaaagaag atataaaact gttaagaaag aaatagacat ttattattcc attgtaagac
    25801 gttaaatgaa atgattcgaa actttaggta ttaaagaact agaagaagaa cgtgggaaaa
    25861 caaaaggatt atgtttaggt agaatgaaac ctaaaggttc gggtactaag attaaacgat
    25921 tggaagaaga gggtgggatg ttagaaaaat gaaggaaagt atgttgcgaa agtaaaactt
    25981 ttaggataat gcacataaaa aagacttctt catctatgtt aagtccgcaa atatatacaa
    26041 ttttataacc atcaaagatt tcaagagaaa ttaaataacc tgagtccata caaatataga
    26101 ctcaggtggc ttagctgcgc tttgaaaata ctgtctacct gacagggccc tctcttttta
    26161 ttcttcaaat aaacaaactg aaacaagact atttagaagt attagtgaat tagcctctct
    26221 ttaattctta tttcgtgtct cttaccttta acaagtacaa acataattca ttaatctata
    26281 ttatctttaa aacaattata aattcgaagc tataaaagca atagaattat gtaataagtg
    26341 aatcaaaaaa acaaccccaa aagcagacat tgtaacctga tatttttcat tctttttttt
    26401 atatacccaa taagcatagt tatataaaag accaattatt gttgtaccaa ctatataagt
    26461 gattccatat cgatgattta atccaaatat aattgaagct attaaaatga taaggtaatc
    26521 gcgattttta atgtgaggaa tccaactcaa tatccaaaat aaaaatactt ga
//
