LOCUS       NZ_PVRL01000002        23507 bp    DNA     linear   CON 21-MAY-2024
DEFINITION  Bacillus thuringiensis strain NMTD81
            NODE_2_length_693722_cov_18.2584, whole genome shotgun sequence.
ACCESSION   NZ_PVRL01000002
VERSION     NZ_PVRL01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis
  ORGANISM  Bacillus thuringiensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 693722)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., W,H. and Gao,X.
  TITLE     Genotypic and phenotypic analysis of antagonistic Bacillus spp.
            isolated from rhizosphere soil of plants in Tibet
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 693722)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., W,H. and Gao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) UG, NordReet, Marienstr. 27a, Greifswald
            17489, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. A5-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 14.5x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002998815.1-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 01:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,177
            CDSs (total)                      :: 6,068
            Genes (coding)                    :: 5,840
            CDSs (with protein)               :: 5,840
            Genes (RNA)                       :: 109
            rRNAs                             :: 11, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 1 (5S, 23S)
            partial rRNAs                     :: 6, 5 (16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 228
            CDSs (without protein)            :: 228
            Pseudo Genes (ambiguous residues) :: 0 of 228
            Pseudo Genes (frameshifted)       :: 100 of 228
            Pseudo Genes (incomplete)         :: 142 of 228
            Pseudo Genes (internal stop)      :: 67 of 228
            Pseudo Genes (multiple problems)  :: 63 of 228
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:59:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 385924
            Orig. end                         :: 409431
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVRL01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23507
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23507
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23507
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13507](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13507
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(674..1219)
                     /locus_tag="C6351_RS06080"
                     /old_locus_tag="C6351_06080"
     CDS             complement(674..1219)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002168863.1"
                     /locus_tag="C6351_RS06080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06080"
                     /product="hypothetical protein"
                     /protein_id="WP_142398764.1"
                     /transl_table=11
                     /translation="MRWKVGTFEKIETNDSSIEKLIHTFKEQNVNGGAVISCFKVHNEN
                     FFKEIPYWKDGHEHFFRRIFNSLDIINSLEELKIHTSEKYKLHFKEKWAVMLDGSIAAQ
                     ILSGGAYEGFKERPVIAKQLAVNVCQYMFQDRYEDIKVFESYCPWTDWFYDVAWDVTWV
                     VLDSRERKMWFICATDTD"
     gene            complement(1301..1563)
                     /locus_tag="C6351_RS33210"
                     /old_locus_tag="C6351_06085"
                     /pseudo=""
     CDS             complement(1301..1563)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001195387.1"
                     /locus_tag="C6351_RS33210"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06085"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQKETAYLWLLRKTFSFALFCLLSVQFTL"
     gene            complement(1580..1942)
                     /locus_tag="C6351_RS06090"
                     /old_locus_tag="C6351_06090"
     CDS             complement(1580..1942)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036573.1"
                     /locus_tag="C6351_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06090"
                     /product="hypothetical protein"
                     /protein_id="WP_001036577.1"
                     /transl_table=11
                     /translation="MNKKTIFYLLTCILLVASTTYIICNKREQVPPILVWDEQEYYVTN
                     EPAKVEEVGQKLGEVTKKIKTSKNPTKNRESNTLQEKTEVFTMIEEEKSEYPPLIIKEA
                     YSDEYRVVRPMLKQVL"
     gene            complement(2075..2257)
                     /locus_tag="C6351_RS06095"
                     /old_locus_tag="C6351_06095"
     CDS             complement(2075..2257)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086895.1"
                     /locus_tag="C6351_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06095"
                     /product="DUF3976 domain-containing protein"
                     /protein_id="WP_001178294.1"
                     /transl_table=11
                     /translation="MQMMYAFGIGLVLFLAVFLFIRKDVQGGTLTKRGFYKLIGCLVVM
                     LIAIIVMIVLINQSL"
     gene            complement(2286..2663)
                     /locus_tag="C6351_RS06100"
                     /old_locus_tag="C6351_06100"
     CDS             complement(2286..2663)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016101524.1"
                     /locus_tag="C6351_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06100"
                     /product="hypothetical protein"
                     /protein_id="WP_001109904.1"
                     /transl_table=11
                     /translation="MNYSQKYFVIMGIIFLFMSGFMILTGIMTHSAPPAITYPLLGMMI
                     MSFCLSYLHPQFKEKDERMKLIRYKGMFVTFFALTVYYLLFSIGLNLKILTLSATELLN
                     ILMALTMSTVFISFVVLAKRY"
     gene            complement(2666..2875)
                     /locus_tag="C6351_RS06105"
                     /old_locus_tag="C6351_06105"
     CDS             complement(2666..2875)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428510.1"
                     /locus_tag="C6351_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06105"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000428510.1"
                     /transl_table=11
                     /translation="MENKMVEYRKKFGLSQEKLAEKLGVSRQTIISIEKGKYDPSLPLA
                     FEIAKTFQTTIEHVFIYEGKEGEE"
     gene            3699..6566
                     /gene="odhA"
                     /locus_tag="C6351_RS06110"
                     /old_locus_tag="C6351_06110"
     CDS             3699..6566
                     /EC_number="1.2.4.2"
                     /codon_start=1
                     /gene="odhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197121.1"
                     /locus_tag="C6351_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06110"
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_000197142.1"
                     /transl_table=11
                     /translation="MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFE
                     IFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAA
                     NGQSLLEKAMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHI
                     QDSEERTWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGV
                     DMLVPVLDEIVLEGAKNGVEDVMIGMAHRGRLSVLAHVLEKPYSHMFAEFKHAKIEGAV
                     ANSGWTGDVKYHLGREQVVSNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSG
                     LPDQDISKSFVILVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSY
                     DSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRMLFKKDFLIDLIGYRRYG
                     HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEVETITQFTQEQLKSDYA
                     QVPPADTSDATIHVKVPDVVAKGIQPIDTGVEIDSLRAINEGLLSWPEGFNVYPKVKKI
                     LERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTN
                     ETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQA
                     LFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSA
                     AQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGT
                     KPNKVKRLVLSTGKMAIDLAAEIESGKHEYNLDEVHVVRIEQLYPFPAEKVQSIIKRFK
                     NLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQE
                     LIVAHALDVKYNFRQDKQEIEVFSN"
     gene            6700..7959
                     /gene="odhB"
                     /locus_tag="C6351_RS06115"
                     /old_locus_tag="C6351_06115"
     CDS             6700..7959
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716916.1"
                     /locus_tag="C6351_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06115"
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_106081456.1"
                     /transl_table=11
                     /translation="MIEIKVPELAESITEGTISQWLINVGDKVEKGGSVVELETDKVNV
                     EIIAEDSGIVSKLLGEPGDTVEVGATIAILDANGAPVAVSTPAPPAEQAKQETAEAPKA
                     AAPNAEKTTSLQGLPNTNRPIASPAARKMARELGIDLNDVRSTDPLGRVRPHDVQAHAA
                     APKEAPAAPKSPAPAPVAKTEFEKPVERVKMSRRRQTIAKRLVEVQQTSAMLTTFNEVD
                     MSAIMELRKERKDAFEKKHDVRLGFMSFFTKAVVAALKQFPLLNAEIQGDELIIKKFYD
                     IGIAVAAPDGLVVPVVRDANQLNFAEIESEIRNLGMKARDNKLSLKELQGGTFTITNGG
                     VFGSLMSTPILNSPQVGILGMHKIQVRPVAIDNERMENRPMMYIALSYDHRIVDGKEAV
                     SFLVAVKDMLEDPKSLLLEG"
     aSDomain        8085..8384
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C6351_RS06120_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="6.20E-58"
                     /identifier="RREFam011.1"
                     /label="C6351_RS06120"
                     /locus_tag="C6351_RS06120"
                     /protein_end="100"
                     /protein_start="0"
                     /score="183.8"
                     /tool="antismash"
                     /translation="MNNLPIHAKLKVNKDTFFLPDSNGGVYFRNNASSFRMDGDGIYDW
                     IEKLMPMFNGNYSLAEITDGLPLPYQNRVFEIGEVLYENGFVRDANQDAPHELNS"
     gene            8085..10004
                     /locus_tag="C6351_RS06120"
                     /old_locus_tag="C6351_06120"
     CDS             8085..10004
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513905.1"
                     /locus_tag="C6351_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06120"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_061668023.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1230.0,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     1.6e-56, bitscore: 183.8, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 7.8e-12,
                     bitscore: 40.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLPIHAKLKVNKDTFFLPDSNGGVYFRNNASSFRMDGDGIYDW
                     IEKLMPMFNGNYSLAEITDGLPLPYQNRVFEIGEVLYENGFVRDANQDAPHELNSTLLD
                     RYASQIEFLEADSHSGALKFETYRGANVLVLGSGDMLTSLVSSLLESGLPTFHYLVTDR
                     DETNYDRIHELIERAYEVDNGVLIQEIDTTIDRPLHEVFEPFDWILYVSQNGDIDGLKT
                     VHTICRETKKNFIPAICLSTLGIAGPVVTENRDECWESAWHRLHETTLQNENSSDSFSP
                     ITSAMLANVIVFELFKHVADDLYREKELQFFLLNYETLEGTWHPFIKHPLATDESFTID
                     TIENLSEKLEHRSNQHTSTDVFRFFDSLTSKEAGIFHVWDEQDSYQLPLSQCYIQVANP
                     LSDGPAPLLPLMTRSGLTHNEARREAGLTGIETYVAEIIHRLIPEHNDIGIGAGETMTE
                     GFYRALQQHLNNKLYERQSHMLEELTTIDLTDIHDKHCRFYYDALATIHETPKIAMSEE
                     ILSFPVVWVGINDKWYGASNINMTLALRSALQLSLLHIQSEETPYRANILPESSIILYD
                     TDSFRVEIQAEEEIPSVQSLQLALQHLEEHNFYPFVFDLAIEPFLKENLDGVYGVLIAK
                     EDGL"
     aSDomain        8115..8351
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C6351_RS06120_Thiopeptide_F_RRE.1"
                     /evalue="3.00E-13"
                     /identifier="RREFam004.1"
                     /label="C6351_RS06120"
                     /locus_tag="C6351_RS06120"
                     /protein_end="89"
                     /protein_start="10"
                     /score="40.6"
                     /tool="antismash"
                     /translation="KVNKDTFFLPDSNGGVYFRNNASSFRMDGDGIYDWIEKLMPMFNG
                     NYSLAEITDGLPLPYQNRVFEIGEVLYENGFVRD"
     gene            10001..11950
                     /locus_tag="C6351_RS06125"
                     /old_locus_tag="C6351_06125"
     CDS             10001..11950
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191877.1"
                     /locus_tag="C6351_RS06125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06125"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_106081457.1"
                     /sec_met_domain="YcaO (E-value: 6e-84, bitscore: 278.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.8e-142, bitscore:
                     470.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQNILLIGDGLLADYVHDQLCKQYSIIRQHTLTEELPENIYLAL
                     VLHDGSPSTIHHDAELIFRSNHIPWLRGFTSFGEGIIGPYIHPLTPGCSHCSDGRRFIA
                     GFDQKEMWELQRKYAFKAENGTRRDVRATQNGMLQMCHLICAETEKILTHNHSSLENEL
                     ILLNLQTLQCTRHSFLPDPLCPVCSSLPDDTADAAEVSLQPSLKVSTETYRCRSIHELN
                     TFLTKDYLDYRIGMLNGKMQHSLLPFADVIINMPLMFGNEGVAGRTHSFAVSEATAILE
                     GLERYCGMSPRGKKTNVHGSFHDLEEHALNPLTLGVHTNEHYNRDNFPFKPFDPDYEQN
                     WVWGYSLSQNRPLLVPESIAYYSLGHRDAFVYETSNGCAIGGSLEEAIFHGILEIVERD
                     AFLLTWYAELPLPRLDLSSANDTELQLMIQRLRTITGYELHAFNATMEHGIPSLWVIAK
                     NTRENGMNVVCAGGAHLDSIRALKSAIQEIAGMLLITDDELEHKREYYEKCLQDPYFVN
                     KMEDHSMLYGLKETEERLHFLLREDAPVQTFQEMNVSQSFDMDLTSDLHQLLNRLHQSN
                     LEIIVVDQTAPLIEKNGLHCVKVIIPGMLPMTFGHHLSRITGLDRVYTVPMTLGYTDEP
                     LTNERLNPHPHPFP"
     gene            11966..13507
                     /locus_tag="C6351_RS06130"
                     /old_locus_tag="C6351_06130"
     CDS             11966..13507
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716912.1"
                     /locus_tag="C6351_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06130"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_016077961.1"
                     /sec_met_domain="PF00881 (E-value: 8.3e-10, bitscore: 34.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLDTFLHHLHFSIDEIMPNHEVDWKDAPLPYKLYRNVPTIPLSL
                     EIPLSLPNSSTTPTLDEIGHYLWYSFGVTQLCQLNSERNVLRRSIPSGGALYPNELYIY
                     LKIDDYPDGIYHYDAAHHRLILLREGNFDSYLADALGNRCNIQSCFGAAFISTMFWKNF
                     FKYNNFSYRLQGLDSGVLIGQLLESAKQFGYTNGVYFQFLDRAMNHLVGLSEGEESVYA
                     VIPLSTEPETNWFHNDYRENKTVTSHELLQQIPPLAHEHFVRSKHVGEYPMITKINEAS
                     MIESTAHFQTLHHEEHYQHNAYAVQLPKVERLSYDFLQLCKKRYSPDADFILTKWDAAE
                     LATLLQEASLSFPYYNDLDGKYANENARVFLYGCFYNVKNIENGAYAYNSKTHSIQPIR
                     YGDLRYPLQSSMTMDNVNLFQVPLCLHVVGKKDYYTRALGYRGYRIHQMEAGILVHKLV
                     FAATAMGMGGHPLLSFDTNSCDQLYGIDAGNETSLIQIPVGAYRARNWLKGVLHS"
     gene            complement(13538..13948)
                     /locus_tag="C6351_RS06135"
                     /old_locus_tag="C6351_06135"
     CDS             complement(13538..13948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996799.1"
                     /locus_tag="C6351_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06135"
                     /product="DUF3908 family protein"
                     /protein_id="WP_000996785.1"
                     /transl_table=11
                     /translation="MAINMKTIEEWIAESNARHEEDFGNVVEEMKEVCIGLDNATLIYT
                     KNVFCFGKKVEVFFFFQDHVVIGQEKDECIEIEKLKYDAITHSNLKTNDKNTMLELKFA
                     NGQSINLDSLNDNYGTKNWLFARQIKSIFKLI"
     misc_feature    complement(14023..14038)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 24.05"
                     /tool="antismash"
     gene            complement(14095..14583)
                     /locus_tag="C6351_RS06140"
                     /old_locus_tag="C6351_06140"
     CDS             complement(14095..14583)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498239.1"
                     /locus_tag="C6351_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06140"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_106081458.1"
                     /transl_table=11
                     /translation="MFVTLQIVQESEKEILRNLYALYLHDLSTFTPNITIEANGFFEYE
                     DLHMFWENDGITPYFIKSDNDIVGFLLLLERPFLKKENDFGINDIFILNQYKGKGIGKQ
                     VIANVLKEKRGQYFVIELVKNIPAVSFWKKVYGELNIEFDEKTQLIDDEECLVQTFEI"
     gene            complement(14685..16019)
                     /locus_tag="C6351_RS06145"
                     /old_locus_tag="C6351_06145"
     CDS             complement(14685..16019)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110220.1"
                     /locus_tag="C6351_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06145"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_106081459.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.6e-65, bitscore:
                     216.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYVIIGGDAAGMSAAMQIVRNDENATVVTLEKGKIYSYAQCGLP
                     YVISGAIASTEKLIARNVKTFRDKYGIDAKVRHEVTKVDTEKKMVYAEHTKTKDVFEFP
                     YDRLLIATGVRPVMPEWEGRELQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGL
                     EMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHHIEILTNENVKAFKGNER
                     VEAIETDKGTYKADLVLVSVGVKPNTDFLEGTNIRKNHKGAIEVNAYMQTNVQDVYAAG
                     DCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMLDKRRAFKGTLGTGIIKFMDLTLART
                     GLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVD
                     KRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE"
     gene            16219..16650
                     /locus_tag="C6351_RS06155"
                     /old_locus_tag="C6351_06155"
     CDS             16219..16650
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332402.1"
                     /locus_tag="C6351_RS06155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06155"
                     /product="hypothetical protein"
                     /protein_id="WP_106081460.1"
                     /transl_table=11
                     /translation="MCAGLLAQLPEEPQEPKEPKPALSLDQEFSINATIYSARAWLSND
                     DTFAQDIWKATQFASASHAGKSIFPVGSVKILNFSDDTITVTASPESDHALKIVVPPHS
                     EAALTSGPLSHIQASTSGGSSKVTFLFHIFFSRDPGSDK"
     gene            complement(16694..17929)
                     /locus_tag="C6351_RS06160"
                     /old_locus_tag="C6351_06160"
     CDS             complement(16694..17929)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017672808.1"
                     /locus_tag="C6351_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06160"
                     /product="YARHG domain-containing protein"
                     /protein_id="WP_106081461.1"
                     /transl_table=11
                     /translation="MNVCTKCGIQFEDGVQFCQNCGTKRGSPVVKKNMSGGAKVGITLL
                     ALFVIAIIGLYLYGSSYYTQVAQVDRMITILQERDGEKLAEIITADDQSVMITKESLTP
                     LFSYIKENPSYVNELKEYLRQGEKQRDGIERADFSLTKDGKYFFIFDRYKLKVKTYYTT
                     LLTNEKGTSLKMNGKEIDKTDDKKFEKQYGPFLPGTQVFQAEYKNDYVKLSREEKVVLM
                     KQGQNNVTIDLTLQGQYITVQTNVPGATLYVNQKPVTALAGEEITWGPVATDGSATIYL
                     ERNGENGRETTKVETVTALPSYNLPFQKKSAEKPVVYNVTPPSTTPYVYNGFIFPDSDI
                     RKLTSTDLAYLSKEQLKIARNEIYARHGHIFQTKDMQTYFSKQSWYRENPYFTGKLTDI
                     ETYNVELIKSRE"
     gene            complement(17949..18734)
                     /locus_tag="C6351_RS06165"
                     /old_locus_tag="C6351_06165"
     CDS             complement(17949..18734)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000650096.1"
                     /locus_tag="C6351_RS06165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06165"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_000650096.1"
                     /transl_table=11
                     /translation="MKCPSCHTENAAEAKFCGNCGHSLTEEVVASSGQEEGPEQARAAQ
                     VKETRPNETVEQAKRFASGYFQFFKHALQAPTAIMKSGTIEVRNGIVSLVLICFLGACI
                     FYRMMSAASAVTRTFAPDISTPTFFVESITVFFFLLILTLFVGFIIFVSGKMMKSSFSF
                     LEVFGIWGTLATPAIAILVLSFLFSFLLIFFLPILLSVAATYIGISITVAILKLDNGGL
                     DLVYTLIIANVLIGIATFIVLWSYISTIIQALTQGITGF"
     gene            18931..19764
                     /locus_tag="C6351_RS06170"
                     /old_locus_tag="C6351_06170"
     CDS             18931..19764
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017762920.1"
                     /locus_tag="C6351_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06170"
                     /product="hypothetical protein"
                     /protein_id="WP_000424512.1"
                     /transl_table=11
                     /translation="MELVNSIFQILLTSVIQLFSLIGVIIVIGFLLGYLESLTRMYWSR
                     AFGRKGFLLTAWIGVPIHELGHAIMCVLFRHKIVATQFFPTDTSQGALGYVQHQYNQKS
                     VYQRIGNFFIGIGPIISGITALILLMRYFVPESYFLFNTTLEKTIASTSINVEMIQNML
                     LSTFVLLKSLFTIGNLLNPSFWLFLFIAICISAHIALSKPDIKGSIDGVIVMFIVLFLF
                     NIIAGLFQYDSNQLIGQVMKYNMYLIAFSSVALLFSCLSTLVSFSFYKIRRGRSF"
     gene            complement(19779..20462)
                     /locus_tag="C6351_RS06175"
                     /old_locus_tag="C6351_06175"
     CDS             complement(19779..20462)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001128607.1"
                     /locus_tag="C6351_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06175"
                     /product="YukJ family protein"
                     /protein_id="WP_001128581.1"
                     /transl_table=11
                     /translation="MPLKNYGVLKGTVIQSKIGKGKTPHYQVHLQDEVGVDYRIAINVK
                     SQSYPSEVLYFASNNIKSEAIHILPTLPFGFTEIKNNEPKVALDYVRGNLFDSKQMIPL
                     PPEKAGADNDLNEKIERYIKRAIEEKAIIYAFGERWGPEENTPDSYFHFKPGNGIHDIH
                     MNQGNVEKWKGDNGIWQDGGILIHFEKEEEWIGIFLAFQSQSWCTDEEGHARVPVEHCD
                     YKGNN"
     gene            complement(20553..22052)
                     /locus_tag="C6351_RS06180"
                     /old_locus_tag="C6351_06180"
     CDS             complement(20553..22052)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015727 - lactate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126004.1"
                     /locus_tag="C6351_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06180"
                     /product="L-lactate permease"
                     /protein_id="WP_000996272.1"
                     /transl_table=11
                     /translation="MAILLALIPIMMIFICLFLFKQTSLRSSLISYAVSVGIVLLSPTF
                     RLGISETVHATIKGWLICFIVGYVLFFGIFLFHLMNKMGYIDQVARFLEEITHDRLLQM
                     LLMCFGICPLIESVSGFGIGFMVAAPIFLSLGYKPFQAVLLSFIGLLASSWGAMATGTI
                     IGSQLINMPLTTLGTNTALLSIPMFAYFVILSLHVVGGWQAVIEKWKEGVGFFLLFSLG
                     IYLSNAYVSVELAGILSSIVTITFGFLIIKLKGKSGQNLITEHAAATEREVSIIKIISP
                     YIFLTVCILLSRLVPALHDLFRSYAVLDLKSYSYKLELLYSPGFWLGMTCLFTIIFFRI
                     PSNIIKQSFSQTIKQWIPFAITTTMFIAISELMGASGMHSLLAKTAGETFGTFFVFVAP
                     FIGAIGGFLTGSNAGSNAMFIKLQMQTAQNVALPWQYVTTLQNTASSVATIACPSRITL
                     GAYLCNIPYRENELLKKTTLMIFGAVLLVVVEVIVWYMLRN"
     misc_feature    22008..22023
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.85"
                     /tool="antismash"
     misc_feature    complement(22144..22158)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     misc_feature    22145..22159
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.41"
                     /tool="antismash"
     gene            complement(22163..22525)
                     /locus_tag="C6351_RS06185"
                     /old_locus_tag="C6351_06185"
     CDS             complement(22163..22525)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946134.1"
                     /locus_tag="C6351_RS06185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06185"
                     /product="DUF4029 domain-containing protein"
                     /protein_id="WP_000946134.1"
                     /transl_table=11
                     /translation="MLRRKLLYLLLTIPLYAWLISMAKIELMALFLGYVFIFSNLNRIQ
                     EQSILEICLFSISIELFSIVSIVLLNELFLRIHSFTLMKFGNIVLQAICTYIVFVVLEK
                     IIGQQTVFQNNRKWGE"
     misc_feature    22554..22572
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.43"
                     /tool="antismash"
     gene            complement(22599..23375)
                     /gene="trpA"
                     /locus_tag="C6351_RS06190"
                     /old_locus_tag="C6351_06190"
     CDS             complement(22599..23375)
                     /EC_number="4.2.1.20"
                     /GO_function="GO:0004834 - tryptophan synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016133917.1"
                     /locus_tag="C6351_RS06190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6351_06190"
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="WP_000537822.1"
                     /transl_table=11
                     /translation="MGVEKIKAAFENGKKAFIPYVMGGDGGLEKLKERIRFLDEAGASI
                     VEIGIPFSDPVADGPTIQRAGKRALDSGITVKGIFQALIEVREEVQIPFVLMTYLNPVL
                     AFGKERFIENCIEAGVDGIIIPDLPYEEQNIIAPLLREANIALIPLVTVTSPIERIEKI
                     TSESEGFVYAVTVAGVTGVRQNFKEEIRSYLEKVKSHVNLPVVAGFGISTKEHVEEMVT
                     ICDGVVVGSKIIELLENEKREEICELIYATKQKEEA"
ORIGIN
        1 tagtcgccat ctttgtcttt ctttaagttc aatgtaactt cgcgagttgc cattgctgca
       61 tctttatctg ctaagttttt gacgatagtt gatgtcattg ttttttcgat tgctttttca
      121 gattgttctt tgtcttcact aaaggcacta gcgaacgcca ttggcataac ttctcccact
      181 gcttttgtta cagcaacgga tagatctgca gatgtaattt tcactttcac ttctgctttg
      241 tcatcctttt tcgatacttc ttctagcttt tcaaatttaa agtttttcgt aattgcactc
      301 agcattgctt ttgcctcagc atcatctgtt ttttcattta gtttattaaa ttccttgtca
      361 ctctcaacaa atgtacgagc cttttctata tcaccttttt gtatcgctgt taaaaattct
      421 tctgtcgtat ctttcggatt tgcacaccct gctaaaacac ctactgttaa tcctactacc
      481 atcattaaca gtaataattt ctttatcttt tgcacgctca ttctcctctt atcttttcta
      541 gtaagtcagc attatataat agtatgaaac tgacattaca aacatttttt agtatatcat
      601 ttatatgatt ctttttctat tcaatcccaa tagataaaga gccttgcagc attcctacaa
      661 ggctctttat ctatcaatcc gtatccgtag cacaaatgaa ccacatttta cgctccctac
      721 tatctaacac cacccaagta acatcccatg caacatcgta aaaccaatct gtccaagggc
      781 aatagctttc gaacacttta atatcttcat agcgatcttg gaacatatat tgacatacat
      841 tcactgctaa ttgttttgcg ataactggtc gttccttaaa tccttcatat gctccgcccg
      901 acaaaatttg agcggcaatg ctaccatcaa gcatgactgc ccatttctct ttaaaatgca
      961 acttatattt ttctgacgta tgtattttta actcttctaa gctattgatt atatctaaag
     1021 agttaaagat tcttctaaag aagtgctcgt gtccatcttt ccaatatggt atttctttga
     1081 aaaaattttc gttatgtact ttaaaacagc ttataaccgc tccgccattt acgttttgtt
     1141 ccttaaatgt atgtatgagt ttctcaatag atgagtcatt cgtttctatt ttttcaaacg
     1201 ttcctacttt ccatctcata acgcccacta ctctctattc aaaatttgtt tcttcattat
     1261 aaatagcaaa ataaaaccca gcaactttaa ggttgctgga ttatctctta tttatattaa
     1321 aaaaaacaat aacaattgct ccaattatat aatgccccgc caccacccac atactccaat
     1381 caaagatcat aagcgataac caaagtgata tattaatagc agcaaataat aaatataaaa
     1441 tgaagtctct cttttgtagt gcccctctat tcattacaat gtaaattgca ccgataggag
     1501 gcaaaataaa gcaaaggaaa aagtttttct taacaaccat agatacgcag tttctttctg
     1561 catatgaatc cccttttcat cataatactt gcttcaacat cggcctcact accctatatt
     1621 catcactata agcttccttt atgattaaag gcggatattc acttttttct tcctcaatca
     1681 ttgtaaacac ttctgttttc tcttgtaatg tattagattc tctattttta gtagggtttt
     1741 tacttgtttt aattttcttt gttacttcgc caagtttttg cccaacttct tctactttgg
     1801 caggttcatt cgtaacatag tattcttgtt cgtcccatac taatataggt ggcacttgtt
     1861 ctcttttgtt acatattata taagtagtac tagctacaag tagtatacaa gttaataaat
     1921 agaagatagt ttttttattc atatactaca ctccttatct atcagttcat tggattatat
     1981 aacacaattt atttacaata aatggattta tcggtaattt ttaggtttaa taataaagaa
     2041 aaaccttacc gaagtaaagt tccgttttta cattctatag tgactgatta attaatacga
     2101 tcattacaat aatcgctata agcataacaa ctaaacagcc gattaattta taaaatcctc
     2161 gcttcgttaa tgtcccacct tgaacatctt tacgaataaa taagaatacg gctaaaaata
     2221 atacaagccc aatgccaaaa gcatacatca tttgcatatg ttaatcttcc tttctctctt
     2281 ccatcttaat atctttttgc caaaacaaca aatgagataa agacggtact catcgtaagt
     2341 gccataagta tattcaataa ttcagtagca gatagtgtaa gtatttttaa gtttaagcca
     2401 atagagaaaa gaagataata tactgttaat gcaaaaaagg ttacaaacat tcctttataa
     2461 cgaatgagtt tcattcgctc atctttttct ttaaattgtg ggtgtaagta gcttaggcag
     2521 aaactcataa tcatcatccc aagcaatgga tacgttatag ccggcggtgc agaatgcgtc
     2581 attatacctg ttaatatcat aaatccactc ataaatagaa agataattcc catgattaca
     2641 aagtactttt gtgaatagtt cattcttact cctccccttc ttttccttca taaataaata
     2701 catgttctat cgttgtctga aatgtttttg ctatttcaaa tgctagcgga agtgatggat
     2761 cgtatttccc tttttcaatt gagataatgg tttgtctgga aaccccgagt ttctcggcca
     2821 gtttttcttg agatagtcca aatttctttc ggtattcgac cattttattt tccaaggaaa
     2881 tttctccctc cttccatata tcgagtatat atgtaaagta aactttacgt caaggttcct
     2941 ttacatttat ttcaatcagt tttcgttcta tttatataga agaaacttgt tcgatttcag
     3001 cacgtctatt ttgtaataaa acatggaaca ctgtatgtaa tcgttactat atttcctcct
     3061 cactttttta aaaatttaat atcttcatat ttgttttatc cttttaaaat atttcattct
     3121 ctgctttatt agatgcaatg tgttatttgt tttacggtgt tttttggcat atttatagaa
     3181 actaacgggt tataaagcat tttttatgtt taaccacttt ttttgtagaa atccttcatt
     3241 ttcctttcga tatttaacac tatcgaaata aagtttatgg taaattcata attttttatt
     3301 ttttatacta tattccgtta tattgttgta taatatctat gaaagcgctt attatttcaa
     3361 tatacataat tcgaatcaac ttttatcaaa acattccaat gattatactt atatttacat
     3421 gtaacaattc tagttttcaa tgtaggtata ccaaatatat ccaccccatt tttctgtaaa
     3481 attactttat aaagtgaaag attaacttgg gtgataagtt attgtgaatg tttttttaca
     3541 aaacagataa gtaatagtgt ttggtattat gtaaattatt gtaataacat aagagtaaag
     3601 aaaacattta cattgattat tggttcatca attattgaaa agagcaaaat gcacctttta
     3661 tatggaaaag gattatatgc attgggaggt ttaaacaaat gacgaggaag aatacaacga
     3721 caaacccttg ggccaagttc cacggtccga accttggtta tgtgattgaa cagtatgatc
     3781 tttacgtaac tggagcaggt tctgttgatc cggaattaca agagcttttt gaaatttttg
     3841 gagctccttc gtttcaagat gatgtcgtaa caggggacaa cacagcaaca catttttctc
     3901 ctcaaaacac aggtaacatt gaaaaaattc ttaaagtcgt tcaacttgtt gagcagattc
     3961 gttctttcgg gcacacgttg gctcacatca acccgatgga agatgctgca aatggacaat
     4021 ctcttcttga gaaagcaatg aacgaactga gcgatgctga cttgaaagcg attccagcga
     4081 aaacagtatg gcaagatgca ccagaaggta ttcacactgc acttgatgta attcatagat
     4141 taaaagacgt ttatacaaaa tctttagctt atgaattttc tcatatacaa gatagtgaag
     4201 aacgcacgtg gttgcatcaa atggtggaat caaattcatt gcgtcaacca ctatcaaata
     4261 aaaaacgaac tgctctttta aaacgtttaa cagctgttga aggtttcgag caattcttgc
     4321 ataaaacatt cgttgggcaa aaacgtttct ctatcgaggg cgttgatatg cttgtgcctg
     4381 ttttagatga aattgttcta gaaggtgcta agaacggtgt agaggatgtc atgattggta
     4441 tggctcaccg cggtcgtcta agcgtacttg ctcacgtatt agaaaaacca tatagtcaca
     4501 tgtttgctga gttcaaacat gcaaaaatag aaggcgcagt agccaattct ggctggactg
     4561 gcgacgtaaa ataccaccta ggtagagaac aagtcgttag taacgaagaa gttagcactc
     4621 gcgtgacatt agcaaataac ccgagtcatc ttgagttcgt gaatcctgta gtagaaggtt
     4681 tcgcacgtgc tgctcaagag aatcgtaaaa aatctggtct tccagatcaa gatatttcaa
     4741 aatcattcgt aattttagtt catggtgatg ctgcattccc tggtcaaggt attgtatctg
     4801 aaacgctcaa cttaagcaga ttgaacgcgt atcaaacagg cggaacgatt catgttatcg
     4861 caaacaatgc agttggtttt acaactgata gctatgattc tcgttctacg aaatattcaa
     4921 gtgaccttgc aaaaggtttc gatattccga ttgttcacgt gaacgctgat gatccagaag
     4981 cttgtcttgc agctgctaac cttgcgattc aatatcgcat gttgttcaaa aaagacttct
     5041 taatcgattt aatcggttac cgtcgatatg gtcataacga aatggatgac ccagcggtta
     5101 cgcaaccaca agtgtacaaa aaaattaaaa atcacccaac tgtaagagca atttatgcag
     5161 atcaattaca agctgctggt gttctaaatg cagatgaggt tgaaacaatt actcagttta
     5221 cgcaagaaca attaaaatcc gattatgcac aagtaccgcc agctgatacg agcgatgcaa
     5281 caattcacgt taaagtgcca gatgttgttg caaaaggcat tcaaccaatt gatactggtg
     5341 ttgagattga ctcacttcgt gcaattaatg aaggtctact atcttggcca gaaggcttta
     5401 acgtatatcc gaaagtgaag aaaattcttg agcgccgtaa agatgcttta gaagagaacg
     5461 gtaaaattga atgggcactt gctgagtcat tagcattcgc ttctatttta caagaaggta
     5521 cgccaattcg tttaactggt caagattcac agcgtggtac atttgcgcac cgtcatatcg
     5581 tattacacga tactgataca aatgaaacat attcaccatt acatcgctta ccaaacatta
     5641 atgcatcatt ctctgttcat aacagtccgt tatcagaggc tgctgttgtt ggttacgaat
     5701 atggttataa cgtattcgct ccagaaactc ttgttatgtg ggaagcgcaa tatggtgact
     5761 tttcaaatac tgcgcaagca ttatttgatc aatatgtttc agctggaaga gcaaaatggg
     5821 gtcaaaaatc tggtttagtt cttctattac cacacggtta tgaaggtcaa ggaccagagc
     5881 actctagtgc acgtccagag cgtttcttac agttagctgc tgagaataac tggacagttg
     5941 caaacttaac gagcgcggca cagtacttcc atatcctgcg tcgtcaagca tctatcttag
     6001 gaacagaagc tgttcgacca ttagtactga tgacgccgaa gagtttatta cgtcacccac
     6061 ttacgctttc aactgctagt cagttaagcg aaggacgttt ccaacctgct ttagaacaag
     6121 aaaaccttgg cacgaaacca aataaagtaa aacgtcttgt tttaagcaca ggtaaaatgg
     6181 cgattgactt agcagcagaa atcgagtctg gtaaacatga gtacaactta gacgaagttc
     6241 atgtcgttcg tatcgagcaa ttgtacccat tccctgctga gaaagttcaa tctattatta
     6301 aacgatttaa aaacttagaa gaaatcattt gggttcaaga agaacctcgt aatatgggcg
     6361 catggcatta catggctcca attctgttcg aacttgctgg agataaagtg aaaacaggtt
     6421 acattggacg tcctgatcgc tctagtccat ctggcggcga tccattcgct cacaaagccg
     6481 agcaagaact aattgttgca cacgctttag atgtgaagta taacttccgt caagataaac
     6541 aagaaattga agttttcagc aactaaaaag taataatgaa ggtttctagc ttgttccctg
     6601 ggcagatatt ctgcccaagg ccaggctaac aaatggagat taccgaagac aaaagaagaa
     6661 aaaacacacc gttaggcaaa taaggggagg acatttaaaa tgatcgaaat taaagtacct
     6721 gagcttgcag aatctattac cgaaggaact atttcacaat ggcttatcaa cgtaggcgac
     6781 aaagttgaga aaggcggcag cgttgttgag cttgaaactg ataaagtcaa tgtagaaatc
     6841 attgcagaag attcaggtat tgtatcgaag ttactaggcg aacctgggga tacagttgaa
     6901 gttggcgcaa ctatcgcaat tttagatgct aatggagcac cagttgcagt aagtacacct
     6961 gcaccacctg ctgagcaagc aaaacaagaa acagctgaag caccgaaagc tgcggctcca
     7021 aatgctgaaa aaactacgag tctacaaggc ttaccaaata cgaaccgtcc tatcgcatca
     7081 ccagctgcta gaaaaatggc tcgtgaatta ggaatcgact taaacgacgt acgtagcaca
     7141 gatccacttg gacgcgtgag accacatgat gtacaagctc atgctgcagc accaaaagaa
     7201 gcaccagctg ctccaaagag cccagctcct gctccagttg caaaaacgga attcgaaaaa
     7261 ccagttgagc gcgtgaaaat gtcccgccgc cgtcaaacaa ttgcaaaacg tcttgtagaa
     7321 gttcaacaaa catctgcaat gttaacaaca tttaacgaag ttgatatgag tgcgatcatg
     7381 gaattacgta aagagcgtaa agacgctttc gagaaaaaac atgatgtacg tcttggcttc
     7441 atgtcattct tcacaaaagc agttgttgca gcattaaaac aattcccatt attaaatgct
     7501 gaaattcaag gtgacgagct tatcatcaaa aaattctatg atatcggtat tgcagtagca
     7561 gctccagatg gattagttgt tccagttgta cgcgatgcta accaattaaa cttcgctgaa
     7621 atcgaaagtg aaattcgtaa tttaggtatg aaagcacgcg ataacaaact ttcattaaaa
     7681 gaactacaag gtggtacatt taccattaca aacggtggtg tattcggttc tctaatgtca
     7741 acaccaatcc taaatagccc tcaagttggt attttaggaa tgcataaaat ccaagtacgc
     7801 ccagttgcaa ttgataacga gcgtatggaa aaccgcccaa tgatgtacat tgctttatct
     7861 tacgatcacc gtattgttga tggtaaagaa gcagttagct tccttgttgc tgttaaagat
     7921 atgcttgaag atccaaaatc attattatta gaaggttgat agattaataa tctaatatat
     7981 aaaggctgta gaatacatca ttctacagcc tttttttgcg ttcatacggg acaaatttca
     8041 tgacataaga taataatgta tgcctaaacg taaggaggat taaaatgaat aaccttccaa
     8101 ttcatgcaaa acttaaagta aataaggata ctttcttcct gcccgattca aacgggggtg
     8161 tctattttcg aaataacgcc agttcatttc gcatggacgg tgatggaatt tatgactgga
     8221 ttgaaaaatt aatgccaatg tttaacggta attattcttt agcagaaata actgatggtc
     8281 tccctctccc ctatcaaaat cgtgtatttg aaattggaga ggttttatat gaaaatggtt
     8341 tcgttcgcga tgcaaatcaa gatgcacctc atgaattaaa cagtacatta ctcgacagat
     8401 atgcttcaca aattgaattt ttagaagctg attctcattc aggtgcttta aaatttgaaa
     8461 cgtaccgcgg agcaaatgtc cttgtacttg gctccggaga tatgcttact tctttagttt
     8521 cttctttatt agaatctggt ttacctacat ttcattacct cgttacagat cgagatgaaa
     8581 caaactatga cagaatacat gagctaatag aacgtgcata tgaagttgat aacggtgtac
     8641 tcattcaaga aatcgatact acaattgacc gtcccttgca tgaagtattc gaaccttttg
     8701 attggatttt atatgtttct caaaatggag acattgacgg tttaaaaaca gttcacacta
     8761 tttgtagaga aacgaaaaag aattttatac cagctatttg tttatcaaca ctcggtatag
     8821 ctggacctgt cgtaacggaa aatcgtgatg aatgctggga atccgcatgg catcggctac
     8881 atgaaacgac tttgcaaaat gaaaattcat cagattcctt ctcaccaatt acatctgcaa
     8941 tgttagcaaa tgtaatcgtt tttgaattgt ttaaacatgt cgcggatgat ttatatcgtg
     9001 aaaaagaatt acaattcttt ttattaaact atgaaacact tgaaggaacg tggcatcctt
     9061 ttataaaaca ccctcttgca actgatgaaa gttttacaat tgatacgata gaaaatcttt
     9121 ctgaaaaact tgagcatcgg tccaaccaac atacttcaac tgatgtattc cgctttttcg
     9181 actcattaac ttctaaagaa gccggtatat tccatgtatg ggatgaacaa gattcatatc
     9241 aattaccgtt atcacaatgc tatattcaag tagccaatcc attatcagat ggcccagctc
     9301 cccttctgcc tcttatgact cgcagtggat tgactcataa tgaagcgcgc cgagaagctg
     9361 gtttaacagg aattgaaaca tatgtagcag aaatcattca ccgccttatt cctgaacata
     9421 acgatatcgg tattggcgct ggagaaacga tgacagaagg attttaccgg gcactacaac
     9481 aacatttaaa taataaattg tatgaacggc agtcacatat gctagaagaa cttacaacga
     9541 ttgatttaac tgatattcac gataaacatt gtagatttta ttacgatgcc cttgctacaa
     9601 ttcatgaaac acctaaaatc gcaatgagtg aagagattct cagttttcca gtcgtttggg
     9661 ttggtataaa tgataaatgg tacggtgcat ctaatattaa tatgacgtta gcgttacgga
     9721 gcgcactaca actatcactg ctccacattc aaagtgaaga gactccttac agagctaata
     9781 tcttgcctga atcatctatt attttatatg acacggattc ttttagggtg gaaatacaag
     9841 cggaagaaga aattccaagt gtgcaatctt tacagcttgc cttacagcat ttagaagaac
     9901 ataattttta tcccttcgtg tttgatttag caatcgaacc atttttgaaa gaaaacttag
     9961 acggtgtgta tggggtatta attgcaaagg aggacggtct atgactcaaa atatattgct
    10021 tataggggat ggccttcttg cagactatgt acatgatcaa ttatgcaaac aatattccat
    10081 cattcgtcag cataccctta cagaagaact tcctgaaaat atttatctcg ctctcgtatt
    10141 acatgatgga tctccttcta ctattcatca tgatgctgag ctaatttttc gctcaaatca
    10201 tattccgtgg cttcgtggtt tcacttcatt tggcgaaggt attatcggtc cttacattca
    10261 tcctcttacg cccggatgtt cccattgttc tgatggacgc cgttttatcg ctggctttga
    10321 tcaaaaagaa atgtgggaac tacagcggaa atatgccttt aaagccgaaa atggaacgag
    10381 gcgtgatgta cgtgccaccc aaaatggcat gttacaaatg tgccatctta tttgcgcaga
    10441 aacagaaaaa atattaactc ataaccattc ttctttagaa aatgaactta ttttactaaa
    10501 cttacaaaca ttacaatgta cgcggcattc ttttcttcca gatcctctct gtcctgtatg
    10561 tagtagttta cctgatgata ctgcggatgc ggcggaagtt tctttacaac cgagtttaaa
    10621 agtaagcacc gaaacgtatc gctgccgttc cattcatgaa ttaaacacat ttttaacgaa
    10681 agactattta gattatcgga tcggtatgtt gaacggcaaa atgcagcatt ctttattgcc
    10741 attcgctgac gtcattataa acatgccatt aatgtttgga aatgaaggtg ttgcaggccg
    10801 aactcattca tttgcagtga gtgaagcaac tgctatttta gaaggtttag aacgatattg
    10861 cggtatgtcg cctcgcggga aaaagacaaa tgtgcatggt agttttcatg atttagagga
    10921 acatgcacta aatcccctta cactcggtgt gcatacaaat gaacactaca atcgtgataa
    10981 ttttccattt aagccgtttg atcctgatta tgagcaaaac tgggtatggg gatattcttt
    11041 atcacaaaac agaccgcttt tagttcctga atcaattgct tattatagcc ttggtcatcg
    11101 agatgctttc gtgtatgaaa catcaaatgg atgtgcaatt ggcggtagtt tagaagaagc
    11161 gatttttcac ggcattttag aaattgtaga gcgtgatgcc ttcttactca cttggtatgc
    11221 cgaattacct cttccccgcc ttgatcttag ttcagcaaat gatacagaat tacaattaat
    11281 gatccagcgg ttacgtacga ttactggata tgaattacac gcttttaacg cgacgatgga
    11341 acacggcatc ccgagcttat gggtaattgc aaagaataca cgtgaaaatg gaatgaacgt
    11401 tgtttgtgcg gggggcgctc atttagattc tattcgagct ttaaaaagtg ccattcaaga
    11461 aatagcaggc atgttactta taacagacga tgagctcgag cacaaaagag aatactacga
    11521 aaaatgctta caagatcctt atttcgttaa taaaatggaa gaccatagta tgctgtacgg
    11581 attgaaagaa acggaagaac gtcttcactt ccttttacga gaagatgcac cggtgcaaac
    11641 gttccaagaa atgaatgtat cacaatcatt tgatatggat ttaacatccg atctccacca
    11701 acttttaaat cgtttgcatc aatctaatct tgaaataatc gttgtagatc aaaccgctcc
    11761 ccttatagaa aagaacggac tacactgtgt aaaagttatt attccaggca tgttaccgat
    11821 gactttcgga caccatctta gtcggattac aggactggac cgggtatata ccgtaccgat
    11881 gacacttgga tatacagacg aacctttaac gaatgaaaga ttaaatccac atccacatcc
    11941 gtttccatag taaaggaggg atttcatgca gctagatact tttttacatc atctccattt
    12001 ctctatcgat gaaattatgc cgaatcatga ggtggactgg aaagacgcac cgcttcctta
    12061 taaattatat cgaaatgtac ctaccatccc gctctcctta gaaatcccat tatctttacc
    12121 gaactcttct actacaccta ctttagatga aattggtcac tacctttggt attcatttgg
    12181 tgtaacacaa ttatgtcagc taaatagcga gagaaatgta ttacgaagat ctattccttc
    12241 aggcggcgct ttatatccga atgaattgta tatctattta aagatcgacg attatccaga
    12301 cggcatttac cattatgacg ccgcgcatca ccggcttatt ttacttcgcg aaggaaattt
    12361 cgattcttat ttagcagacg cactcggtaa tcgctgtaac atacagtctt gtttcggtgc
    12421 tgcatttata tctactatgt tttggaaaaa tttctttaaa tacaataatt tttcatatcg
    12481 tcttcaagga ttagatagcg gggtccttat tggacaatta ctagaaagtg caaaacagtt
    12541 tggctacaca aatggcgtat attttcaatt tctagaccgg gcaatgaatc acttagtcgg
    12601 attgtcagaa ggtgaagaaa gtgtgtatgc cgttattcct ttaagtacag agccagaaac
    12661 taattggttt cacaatgatt accgtgaaaa taaaacagtt acttctcatg agttgttgca
    12721 acaaattccg ccgttagcac atgaacattt cgttcgctca aaacatgtag gtgaatatcc
    12781 gatgataaca aaaataaatg aagcttctat gatcgaatcg acagcacact tccaaacact
    12841 acatcatgaa gagcactatc aacataatgc gtacgctgta cagctaccaa aagtagaacg
    12901 gttatcgtat gatttcctac aactttgtaa aaaacgatat tctcctgatg cggactttat
    12961 tttaacgaaa tgggatgcag ccgagctcgc tactttacta caagaagcga gcctctcctt
    13021 cccctattac aacgaccttg acggtaagta tgcaaatgaa aatgcacgcg tcttcttata
    13081 tggatgtttt tataacgtga aaaatattga aaacggggct tacgcttata atagtaaaac
    13141 acattcgata caaccaattc ggtatggaga ccttcgttac cctcttcaat ctagtatgac
    13201 gatggataac gttaaccttt ttcaagtacc actttgctta catgtagtcg gaaagaaaga
    13261 ttactataca cgtgcattag gctatagagg atatcgtatt caccaaatgg aagctggtat
    13321 actcgttcat aaactcgttt ttgcagcgac cgcgatgggg atgggcgggc atccattact
    13381 tagttttgat acaaattcat gtgatcaatt gtacggtatt gatgctggga atgaaacgtc
    13441 tcttattcaa attcctgttg gggcgtatcg agcgcggaat tggttaaaag gggttttgca
    13501 tagttaaaag cacgccgatg gacggcgtgc ttttttacta gattaactta aaaatactct
    13561 taatttgtct agcaaataac caatttttcg taccgtagtt atcatttaaa ctatctaaat
    13621 tgatagattg tccgttagca aactttaatt ctagcattgt atttttatca tttgttttta
    13681 agttactatg tgtaatagca tcatacttta atttttcaat ctcaatacat tcgtcttttt
    13741 cttgtccaat cacgacatgg tcttggaaga agaaaaagac ttctactttt ttaccgaaac
    13801 aaaatacatt tttcgtatag attaatgtcg cgttatcaag tccgatgcat acttctttca
    13861 tctcttcaac aacgtttcca aagtcttctt catgtcttgc gtttgattca gcaatccatt
    13921 cttcgattgt tttcatgtta attgccatac tgcgccccct ggttcgttca ttgctttatt
    13981 taaaaataaa tactatatga aaatataagc gataagtact atgttttcaa gggtaaacgg
    14041 tatattcgaa ataaagttaa atttcaaagt aatatactag gtgcatcgat ttcattatat
    14101 ttcaaacgtt tgaacgagac attcttcatc atcaattaac tgtgttttct catcaaattc
    14161 gatgtttagc tccccatata ctttcttcca aaaagaaact gctggtatat ttttcacaag
    14221 ttcgataacg aaatactgcc ctcgtttctc ttttagtaca ttcgcaataa cttgtttacc
    14281 gattcctttc cctttgtact gattcaatat gaaaatgtca tttataccaa agtcgttttc
    14341 cttcttcaaa aaaggacgtt ccagtagtaa caaaaatcct acaatatcat tatcactttt
    14401 aataaaatac ggagtgattc cgtcattttc ccaaaacatg tgcaaatctt cgtattcgaa
    14461 aaatccattt gcctcaatcg ttatattagg agtgaatgta gagaggtcat gaagatatag
    14521 tgcatacaaa ttacgcaata tttctttttc tgattcttga actatttgaa gtgttacaaa
    14581 catttttaaa gatccccttc cctatatgta actgtttctt cctctttatt attcgctaaa
    14641 aaagtttacc tacctttgca aaaaaaatag cactttaaaa agtgctattc cgctctcctt
    14701 gccgcttgct gaattgggtc ccacacgctg ttatatggtg gtgcgtaact taagtcgaca
    14761 tcttctaaat cgtgaatgct cattttattg aaaagtgcca ttgcgatcac atcaatccgt
    14821 ttatctacgc cttcttctcc aattacttgc ccgcccaata attgtttcgt atcggagcga
    14881 tatagtaatt tcaagtaaag tggttttgca tttggataat agcccgccat atttgtagaa
    14941 tctactttga ccgttttata cggaatgtgt agcccttttg cttctttttc atttaaccct
    15001 gttcttgcga gtgtcaaatc cataaattta ataatgcctg tgcctaacgt acctttaaaa
    15061 gctcttcgtt tatcaagcat attcagtcca gcaagtcgcc cttgcttatt ggcagtcgtt
    15121 ccgagcggga tatgatcatg aatttccttt ataacgtggt aatgtgttgc gcaatcaccg
    15181 gctgcatata cgtcttgcac atttgtttgc atatatgcat ttacttcgat tgctccttta
    15241 tgattcttac gtatatttgt cccttcaaga aaatcagtat ttggcttcac tccaaccgac
    15301 actaaaacaa gatctgcttt atacgtacct ttatccgttt cgattgcttc tactcgttca
    15361 tttcctttaa atgcttttac attttcattc gttaaaattt caatatgatg cttatctgct
    15421 tctttatgta tgtactctgc catatctgca tcataaatcg taccgatatg atcatttcgc
    15481 tcaatcattc ttactttctt accaagttcg acgaatgttt ctgccatctc aagtccaatg
    15541 gcaccaccgc caataatcgt tacatcttca actttattcg tttctagcgt ttttaatatg
    15601 cgctcagcat caggaattgt ttttaaaaga tgaacgcctt gtaattcccg tccttcccat
    15661 tctggcataa caggacgcac tccagtcgca attaataatc gatcatatgg aaattcaaag
    15721 acatctttcg tcttcgtatg ctctgcgtac accattttct tttccgtatc tactttcgtt
    15781 acttcatgtc gtactttcgc atcaattcca tatttatcac gaaacgtctt cacattacgc
    15841 gcaattaatt tttccgttga agcgatagca ccactaatga catatggtaa cccacactgc
    15901 gcgtacgaat aaattttacc tttttctaac gttacaacag ttgcattttc atcgtttcta
    15961 acaatttgca tagctgcact cataccagct gcatctccgc caataatgac atagttcact
    16021 ttaccactcc ttctttttta catactcttt acgttttcca tattttatag aaataacacc
    16081 tatttccatt gtaaagaaag agaattccat cttcaaattt ggtgcacaaa cctatgcttt
    16141 aataggtagc cgtcgtgtct tataaacaac atgtttaata tgctataaca gtaacgatcg
    16201 aaagtaggtg aaacatacat gtgcgccggc cttctcgccc agcttccaga agaaccgcaa
    16261 gaaccaaaag aaccgaaacc cgccctctca cttgaccaag aattttccat taatgcaaca
    16321 atatacagcg ctcgcgcttg gttatctaac gatgatacgt ttgcacaaga tatttggaaa
    16381 gctacccaat tcgcttcagc atcacatgct ggcaagtcca tctttccagt cggttcagtt
    16441 aaaattctga acttctctga cgatacaata actgttactg cttcaccaga atcagatcat
    16501 gcgctcaaaa tagtcgtacc cccccattcc gaggcagccc taacatctgg tcctttatca
    16561 catatacaag ctagtacatc aggaggatca agtaaagtca catttctctt tcacatcttt
    16621 ttctcaaggg atcctggttc agataaataa ccataaaaaa ggtacagtta tgcactgtac
    16681 ctttttcaca tgtttattct cttgatttga tgagttcaac attataagtt tcaatatctg
    16741 ttagctttcc tgtaaaatat ggattttctc tataccaaga ttgttttgaa aaatacgttt
    16801 gcatatcttt cgtctgaaaa atatgtccat gccttgcata tatttcattt ctagcaattt
    16861 tcaactgttc tttcgataaa tatgctaaat ctgtactcgt taattttcga atatcactat
    16921 ctgggaaaat gaaaccatta tatacatacg gagtggtaga tggcggagta acattgtaaa
    16981 caactggttt ttccgcactt ttcttttgga atggaagatt ataagacgga agtgcagtta
    17041 ccgtttctac cttcgtcgtt tcccttccgt tttctccatt tcgttctaaa taaatcgtcg
    17101 cacttccatc agttgctaca ggcccccatg taatttcttc tcctgccagc gctgtaactg
    17161 gtttttgatt cacatacaat gttgcaccag gcacgttcgt ttgaaccgta atatattgtc
    17221 cttgcaacgt taaatctatc gttacgttat tttgaccttg tttcataagt acaacctttt
    17281 cttcacgtga tagtttcaca taatcatttt tatattctgc ttgaaacact tgagttcctg
    17341 gaagaaacgg tccatattgc ttctcaaact ttttgtcatc tgttttatct atttcttttc
    17401 cgttcatttt taaagatgta cctttttcat ttgtaagcaa tgtcgtataa tacgtcttca
    17461 ctttcaattt ataccgatca aatataaaaa aatactttcc gtctttcgtt aacgaaaaat
    17521 cagctctttc tattccgtcc cgttgttttt caccttgtct caaatattct tttaattcat
    17581 tcacatacga tggattttct tttatatatg aaaatagagg cgttaaactc tcttttgtta
    17641 tcataaccga ttgatcatct gccgtaatga tctcagctaa tttctctccg tccctctctt
    17701 gtaaaatcgt aatcatccga tctacttgtg ccacctgcgt ataatacgat gatccgtaca
    17761 aatataatcc aataatcgct ataacaaata gtgctaacag tgtaatgcca acctttgcac
    17821 caccgctcat gttcttcttt actacaggac ttcccctctt cgtcccgcag ttttgacaaa
    17881 attgcacacc atcttcaaac tgaattccgc actttgtaca tacattcatc cagtcaacca
    17941 ccttttcatt agaagccagt tattccctgt gttaaggctt gaattatcgt gctaatgtaa
    18001 gaccaaagta caataaatgt tgcaattcca attaaaacat ttgcaataat aagtgtgtac
    18061 acgagatcta atccgccatt gtctagcttt aatatggcta cagttatact aatccctata
    18121 taagttgcag ctaccgataa taatatcggt aagaaaaaga ttaataagaa actaaaaaga
    18181 aaagaaagga ctaatatagc aatagccggc gtcgctagcg ttccccatat accgaatact
    18241 tcaagaaacg aaaaagatga tttcatcatc ttaccactta caaaaataat aaatccgaca
    18301 aataaagtta aaattaataa aaagaaaaag accgttatag attctacaaa aaatgtggga
    18361 gtagatatat ctggtgcaaa tgttctcgta actgctgatg ctgcactcat cattctataa
    18421 aaaatacatg ctcctaaaaa acaaataaga acaagactta caattccatt tcttacttca
    18481 atcgtgccgc ttttcataat cgctgtcggt gcttgtaatg catgtttaaa aaattgaaaa
    18541 tagccgctcg caaaccgctt cgcttgctct accgtttcat ttggccgagt ttcctttact
    18601 tgtgccgcgc gtgcttgttc cggcccttct tcttgaccac tacttgccac tacttcttcc
    18661 gttaacgaat gtccacaatt cccgcaaaac tttgcctctg ctgcattttc tgtatgacat
    18721 gacggacatt tcattctctc atccctcctt aagcatatac catatagggt gttacaaatt
    18781 caatatatga ctttgtacat aaaacatgac tacaagaaaa agattctgaa atccttcttt
    18841 caaaagaaat tatatatgct agcaatcttg aaaaataatg ctattatgaa acagaacaaa
    18901 taacattttt aacagattgg atgaaagaca atggaattgg taaactcaat ttttcaaata
    18961 ctccttacaa gcgtaatcca attattttcc ttaattggcg ttatcattgt aattggattt
    19021 ctattaggtt atttagaatc actaacacga atgtattggt cgagggcttt cggaagaaaa
    19081 ggattccttt taacggcgtg gattggtgtt ccgatccacg aacttggaca tgccattatg
    19141 tgcgtactgt tccgtcataa aattgtagca acgcagtttt tcccaacaga tacaagtcaa
    19201 ggagcattag gttacgtaca acatcaatac aatcaaaaaa gtgtgtatca acgaattggg
    19261 aatttcttca tcggcatcgg gcctattatt tctggtatta ctgcattaat ccttttaatg
    19321 cgctatttcg taccagaatc atatttttta tttaatacaa ctctcgaaaa aacgatcgct
    19381 tctacttcta ttaatgtaga aatgattcaa aacatgctct tgtcgacgtt tgtattattg
    19441 aaaagcttat ttacaatcgg caatttattg aatccttcct tttggttatt tttatttatc
    19501 gccatttgta tttccgcaca tatcgcttta agtaaaccag acattaaagg atcaatagac
    19561 ggagttatcg tcatgtttat cgttttattt ttattcaaca tcatagcggg actgtttcaa
    19621 tacgacagta accagctaat tggacaggtt atgaaatata atatgtatct cattgcgttt
    19681 tctagtgtag cactgctttt ctcttgtctt tctacactcg ttagtttttc gttttataaa
    19741 ataagaagag ggcgttcttt ttgaacgccc tcttcttatt aattattccc cttataatca
    19801 caatgctcaa caggcacacg agcatgccct tcttcatcgg tacaccatga ctgtgattgg
    19861 aatgcaagaa agataccaat ccattcttct tccttttcaa agtgaatgag tatccctccg
    19921 tcttgccata tgccattatc acctttccat ttctctacat tcccttgatt catgtgaata
    19981 tcatgtatac cgtttcctgg tttgaaatga aaataggaat ctggtgtgtt ttcttctggt
    20041 ccccatcttt caccaaacgc gtaaataatc gctttttctt ctatcgctcg ctttatataa
    20101 cgttctattt tttcgtttaa atcattatct gctcctgctt tttcgggagg caaaggaatc
    20161 atttgttttg aatcaaatag atttcctctt acataatcta aagccacttt cggttcattg
    20221 ttttttattt ctgtaaaacc gaatggtaat gtcggtaaaa tatgaatcgc ttctgattta
    20281 atattgttac tcgcaaaata taaaacttct gacggataac tttgcgattt tacgttaatt
    20341 gcaatacgat aatctactcc tacttcatct tgtaaatgaa cttgataatg aggtgttttc
    20401 ccttttccaa tctttgattg tataactgta ccttttaaca caccgtagtt ttttaggggc
    20461 atacatttca tctcctattc atttagtaga agctattcat atttaaatca ttatccactc
    20521 ataaaaaaaa tcctcctatg ttagggggat ttttaatttc tcaacatata ccaaacaata
    20581 acctctacca ctacaagtaa aaccgcacca aagatcatta acgtcgtctt ctttaatagt
    20641 tcattttcac ggtaagggat attacataag taagcaccta atgtaatccg tgatggacaa
    20701 gcgattgtcg ctactgatga tgcggtgttt tgaagtgttg tgacatattg ccacgggagt
    20761 gctacgtttt gtgcggtttg catttgtagt tttataaaca ttgcatttga tcctgcgtta
    20821 ctacctgtta aaaatccacc aatagcgcca ataaacggag caacaaaaac gaaaaaggtt
    20881 ccaaatgttt caccagctgt ttttgcaagt aatgaatgca tgccagatgc acccattagt
    20941 tctgaaatgg cgataaacat tgtcgtcgta atagcaaatg gaatccattg tttgatcgtt
    21001 tgtgagaatg attgtttaat aatattagac gggatgcgga agaaaataat agtaaataag
    21061 caagtcatac cgagccaaaa tcctggtgaa tatagtaact ctagtttata agagtatgat
    21121 ttcaaatcaa gaaccgcata tgatctgaac aaatcatgta atgctggaac gaggcgagaa
    21181 agtaaaatac aaactgttag aaatatataa gggctaataa tttttataat ggatacttct
    21241 ctctccgttg cagcggcatg ttctgttata agattttgcc cactttttcc ttttaattta
    21301 atgataagaa agccaaatgt aatcgtaact atagaactta atatcccggc tagttcaaca
    21361 cttacgtacg cattagaaag atatattccg agagaaaata atagaaagaa ccctactcct
    21421 tctttccact tttctataac cgcttgccag ccgccaacaa cgtgtaaaga aagaataacg
    21481 aagtaagcaa acatcggaat acttaatagc gctgtatttg taccaagtgt tgtaagaggc
    21541 atatttatta gctgcgaacc gataatcgta cccgttgcca ttgcgcccca tgaactagct
    21601 agtaagccga tgaatgagag cagtacagct tgaaatggtt tatagcctag cgaaagaaaa
    21661 ataggtgctg caaccatgaa tccaatacca aatccactta ctgattcaat aagcggacaa
    21721 atgccaaaac acataagcag catttgtaat aagcgatcat gtgtgatttc ttctaaaaaa
    21781 cgtgctactt gatcgatgta tcccattttg ttcatgaggt gaaataaaaa aataccgaaa
    21841 aataaaacgt acccgacaat aaaacaaatt aaccatcctt taatcgttgc gtgcacagtt
    21901 tcacttatcc ctaatcgaaa cgttggcgag agtaaaacga ttccgacaga cactgcataa
    21961 gaaattaacg aggaccttaa tgacgtttgt ttaaataaaa ataaacaaat gaaaatcatc
    22021 ataattggga taagtgccaa caatatggcc atgttatcat ctcatttcgt ttaaaataca
    22081 atttttaact attatataac agatgacata attttcaatt gtttttacaa cagattcaaa
    22141 aaaggggcca aacggctcct tttcattcac cccattttct attattctga aaaactgtct
    22201 gctgcccaat tattttttct aacacaacaa acacaatgta agtacatatt gcttgcaata
    22261 caatattccc aaatttcatt aatgtaaatg aatgaatccg tagaaataat tcgtttaata
    22321 atacaatcga aacgatacta aataattcta tactaatcga aaatagacat atttctaaaa
    22381 tagactgttc ttgaatgcga tttaagttgg aaaagataaa tacatatcct aaaaatagag
    22441 ccatcaactc tattttcgcc atgctaatga gccaagcgta tagtggtata gttaaaagaa
    22501 gatacagtaa tttgcgtctt agcatgcctt ctcacctctg aattaaatgt attttctgta
    22561 tattttaaca tttattacgc aaaacaaaaa gaagagactt acgcctcttc tttttgtttt
    22621 gttgcatata ttaattcaca tatttcttct cgtttttcat tttctaaaag ctcaatgatc
    22681 ttacttccaa caacaactcc gtcacatatt gtaaccattt cttctacatg ttcttttgtt
    22741 gaaataccga atcctgcgac tactggtaag ttgacgtgtg attttacttt ttctaagtaa
    22801 ctacgaatct cctctttaaa gttttgacgt actcccgtta cgcccgctac tgtaacagcg
    22861 tagacgaatc cttctgattc actcgtaatt ttttcgattc gctcaattgg gctcgttacg
    22921 gtaacgagtg gaattagcgc aatgtttgcc tctcgaagta acggcgcaat aatattttgt
    22981 tcttcatatg gtaagtctgg aatgatgatg ccgtctacac ctgcttctat gcagttttcg
    23041 atgaatcgtt cttttccaaa tgcgagtact ggatttaaat atgtcatgag tacaaacgga
    23101 atttgcactt cttcccttac ctctattaat gcttgaaaaa ttccttttac tgttataccg
    23161 ctatctagcg ctcgcttccc tgctctttga atcgttgggc catctgcaac tggatctgaa
    23221 aacgggatac caatttcaac gatgcttgct cctgcttcgt ctagaaaacg aattctttct
    23281 tttaatttct caagtccacc atctccgccc attacgtacg gaataaatgc tttcttacca
    23341 ttttcaaacg ctgctttaat tttttctact cccatttttc acacctcttc catataacgt
    23401 tttatactct ctacatcttt atcaccgcgg cctgataagc aaatgacaag tccttcgtct
    23461 ttcttcattt gcggcgctaa ttttaatgca tatgcgacag catgtga
//
