LOCUS       NZ_PVQN01000002        21610 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Bacillus atrophaeus strain NMTD54 NODE_2_length_835950_cov_40.1502,
            whole genome shotgun sequence.
ACCESSION   NZ_PVQN01000002
VERSION     NZ_PVQN01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus atrophaeus
  ORGANISM  Bacillus atrophaeus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus.
REFERENCE   1  (bases 1 to 835950)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Genotypic and phenotypic analysis of antagonistic Bacillus spp.
            isolated from rhizosphere soil of plants in Tibet
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 835950)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAR-2018) UG, NordReet, Marienstr. 27a, Greifswald
            17489, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. A5-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 37.5x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002998075.1-RS_2024_11_19
            Annotation Date                   :: 11/19/2024 01:09:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,355
            CDSs (total)                      :: 4,263
            Genes (coding)                    :: 4,053
            CDSs (with protein)               :: 4,053
            Genes (RNA)                       :: 92
            rRNAs                             :: 7, 8, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 7, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 210
            CDSs (without protein)            :: 210
            Pseudo Genes (ambiguous residues) :: 0 of 210
            Pseudo Genes (frameshifted)       :: 109 of 210
            Pseudo Genes (incomplete)         :: 155 of 210
            Pseudo Genes (internal stop)      :: 17 of 210
            Pseudo Genes (multiple problems)  :: 64 of 210
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:02:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 158868
            Orig. end                         :: 180478
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVQN01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21610
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21610
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21610
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11610](-)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11610)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(146..158)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     misc_feature    441..454
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.42"
                     /tool="antismash"
     misc_feature    complement(462..475)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.67"
                     /tool="antismash"
     misc_feature    complement(870..886)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            complement(1050..1604)
                     /locus_tag="C6W23_RS05835"
                     /old_locus_tag="C6W23_05830"
     CDS             complement(1050..1604)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326492.1"
                     /locus_tag="C6W23_RS05835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05830"
                     /product="YdhK family protein"
                     /protein_id="WP_003326492.1"
                     /transl_table=11
                     /translation="MKRNTTLIGIVSLLLLLMLSACGSDNQDKKSDQTMNMDDTHTHSE
                     SSEIPEGLTAAQHPTYKVGSQAIIKADHMKGMKGAEATITGAYDTTAYAVSYTPTTGGT
                     RVENHKWVIQEEIKNASDETLKPGTDVIIEADHMKGMKGATGKIDSAEKTTVYTVDYTP
                     TTGGEKVKNHKWVTESELSSK"
     gene            1887..3248
                     /locus_tag="C6W23_RS05840"
                     /old_locus_tag="C6W23_05835"
     CDS             1887..3248
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326493.1"
                     /locus_tag="C6W23_RS05840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05835"
                     /product="YncE family protein"
                     /protein_id="WP_106033729.1"
                     /transl_table=11
                     /translation="MKKIERSFKEKAVRQQEDCLCFCEEEASREAMFQAPIEVPEGFVV
                     DPAEAVANVTWNADSLSCVSERCFIQTGPGPDEIEIHFAVRLQGTITLLVSVSPVRNQY
                     GQGEGAVSVIHNVEIDQVVYYSDEPDDCPDFSDITIENLVVVPPFYGSPLSVTGTIVLA
                     PEPEPEPVYAFTANPDDQSVSVIDTNTHTVITTISLPYEPTGIEITPDKASTFVLHFNN
                     SVISVIDNGTLTVTGSIPLDQPPETIKFMPEHDFAYVLAGNAIYVIRIETSAVERSIPV
                     EGYDIAIDPNGLFAYVLDFGLVQKVDLSTGEVTGMIERELIVNSIETKPPERYAYVLEQ
                     DHFLNYLTVIDLNTFTISNTQELEYEGEYQMFKSGSGLYLFDGFTHNLYSVSPSGAGVI
                     GNLPQSARDFAFTPNGEFLYATRFIEQSIIVYNTDGYSVETVISLGVSPSDIAI"
     gene            3288..4664
                     /locus_tag="C6W23_RS05845"
                     /old_locus_tag="C6W23_05840"
     CDS             3288..4664
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012118684.1"
                     /locus_tag="C6W23_RS05845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05840"
                     /product="YncE family protein"
                     /protein_id="WP_106033730.1"
                     /transl_table=11
                     /translation="MKKNDLSAFQENCFCFCDEEISREALFQVPIEVPEGFTIDSAEAA
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVQYAVRLQGTVTLLVSVSPVRNQYGQGDGA
                     VSVIHNAEIDQVVYYSDNPDDCPDFSDITIENLVVVPPFYGSPLSVMGTIVLVSAPDQR
                     SYVFTANTGDSTVSVIDTDVNTLVSTISLSDIPTDLSVTLDKAYTYVLHRNANLVSIIN
                     NETLTVTQTIPLAGAPRKIQFETGGGFAYILAGGSSIYEINISSQTITNTFTVSPAADD
                     FALDPNGQFFYTTNSVSWVVNKYDINTGQLIDSLSNFETPNLIETPLIGDFAYLENGEL
                     RPNGVSVIDLTTFSESSKINRLFDGLITIVFSADGTRAFFLEPYFEVFPENLTVVDTAQ
                     HTFITTASLPGASDLAVAPDNQYIYVAQPAANTVTVYRTSDYTAVAVIPVGAGPSAISM
                     "
     gene            complement(4671..5372)
                     /locus_tag="C6W23_RS05850"
                     /old_locus_tag="C6W23_05845"
     CDS             complement(4671..5372)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015250988.1"
                     /locus_tag="C6W23_RS05850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05845"
                     /product="bacteriocin biosynthesis protein AlbG"
                     /protein_id="WP_106033731.1"
                     /transl_table=11
                     /translation="MKKSTVFTVLLLLMVMAAYSFGWFQASAEAAGQYVQLIKNDYVRL
                     GLLSCAASVLMLPAFLYLHYVTRSVKSMTAAFQKITQSHQSCCDFQHRKLCSRYAGDVK
                     SLRESYKGIRQTYVMGAVLCQVIVFGYMFEVVKAVPFSFHTPPAVTKGIAIVLIIYLLF
                     YMRSYLLQLLQNGQTAKKAVVLLLAGAGIWWMLSFTMSELLFLILLAAIQQTGSLVYKR
                     ITYRSPASLDL"
     gene            complement(5369..6646)
                     /locus_tag="C6W23_RS05855"
                     /old_locus_tag="C6W23_05850"
     CDS             complement(5369..6646)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015483836.1"
                     /locus_tag="C6W23_RS05855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05850"
                     /product="pitrilysin family protein"
                     /protein_id="WP_106033732.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 4.1e-13, bitscore:
                     45.3, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKETFFHQLDARTEITYADNGLKICRVKFPNAHMRLCNVKVNFG
                     SRDIRLHSGDSEKVLPYGTAHFLEHVLFWHNGRNLYSDFFDHGALLNAFTTYTDTNFMF
                     TSLPDRLEHTIPKLLDALWNPSFDENIVAQEKSVIKSEIETAHLNQQLHYHYQMLNLLS
                     PASPAAIFPAGRTEDIEALTINDLKEAYATGYQPQRMTMFLIGGSEDTETILPSHLRLR
                     GRSGHTAKRKFMPACPPFLQNQSLGDAECSGETWTGLHIGALPDKNDLFTLQMYWDIIS
                     RVLFHIDSPLFQEIRQTRLLNIQSLSAESHVSEDGGFLILHGKGAHSSAYIDVAAYYVM
                     QQKCQAEAWLEYGKESLLNAIIYDSDYVRKCFEWAAECERYDCSFFELYRLIQNMTVQD
                     FLYLIDTVASAKKVTIHVSHPEVVGQ"
     gene            complement(6652..7842)
                     /locus_tag="C6W23_RS05860"
                     /old_locus_tag="C6W23_05855"
     CDS             complement(6652..7842)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326497.1"
                     /locus_tag="C6W23_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05855"
                     /product="insulinase family protein"
                     /protein_id="WP_106033733.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 2.6e-07,
                     bitscore: 26.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQGEKVNDLEMNLLTTDQFSTISIAASFLKPIEIAAEPEEETIY
                     FYGAAAYLKQNITDIFGYAAGSRFIYSANLFFDRQLKTYGTRLIHPLYHKNLNIDDVLE
                     TFVDRSSLPASLPADIAETAKADLLLKIEKKFADPFSYSAARLAEETFGSPMYGTAMFG
                     RKEKVQAIQPKRFLDASDFKTDLLSQQKQLYVIGNVQELHAGGYSRHAPSMNGRRKPVN
                     KNIYETETRSTAGPSVMTLGFDCGEMNGFRDYIKIQLIDGLLGKYGHSALFRHFREKQM
                     AVYHVITRYDIMSNLLLVSVCTDRVQEKEIPPRVIETVMNFHVDEQELEKAKQFLKNEI
                     LLQLDSPEGLLAYMGILRHYSYKKEDILDGISTITCRDLLQYVTNIEYIGAHVVRG"
     gene            complement(7790..9118)
                     /locus_tag="C6W23_RS05865"
                     /old_locus_tag="C6W23_05860"
     CDS             complement(7790..9118)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326498.1"
                     /locus_tag="C6W23_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05860"
                     /product="bacteriocin biosynthesis protein AlbD"
                     /protein_id="WP_106033734.1"
                     /transl_table=11
                     /translation="MNNVFQILTLLFKQLYGRQGKKDAIRITAGLAVLALFEIGLIRQA
                     GIDESVLGKTYVTLALLFMNVYMVFLSISSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGTGTLSGTETLFWLGKFSFFTVYSILLGVLLSNLFVKKKG
                     FVFLLHAAAFACICASVVFMPALTIPLCGVHMAWGVFFDFPSFLQVPDQQNKMHSFMRT
                     SEFSFYKREWNRFISSKAMLLNYIVMAAFSGFFSFQMMKTGIADQHIIYIVITALLLIC
                     SPIALLYSLEKNDRMLLITLPIKRRTMFWAKYRFYSGLLAGGFILIAMIVGLISSQPIS
                     FMTFLQCIELLLMGAFIRLTSDEKRPSFGWQTEQQLWSGFSKYRSYVFCIPLFLATIAG
                     TVISLAIIPIAGLIIVYLLQKQEGGFFDTRRKSERFGNEPVND"
     gene            complement(9111..9830)
                     /locus_tag="C6W23_RS05870"
                     /old_locus_tag="C6W23_05865"
     CDS             complement(9111..9830)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="C6W23_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05865"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_106033735.1"
                     /transl_table=11
                     /translation="MSMLDIHALSVWYEQDNVILENVDLHLEKGDVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGSFKLCGIEVNAKTPLKTLDQLKTNRYFAADYPLLFTEITAKEYVS
                     FVHSLYQKEFHEQQYVSLAEEFHFSQYTNRRISELSLGNRQKVVLLTGLLLRAPLFILD
                     EPLVGLDVESIEVFYEKMQEYCKAGGTILFSSHLLDVVKRFCHYAAILHDKQIRKLIPI
                     KDDTDLRREFFEVIGHE"
     gene            complement(9827..9988)
                     /locus_tag="C6W23_RS05875"
                     /old_locus_tag="C6W23_05870"
     CDS             complement(9827..9988)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="C6W23_RS05875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05870"
                     /product="bacteriocin biosynthesis protein AlbB"
                     /protein_id="WP_003326500.1"
                     /transl_table=11
                     /translation="MSPTQRKWLLYILSFVFVIGAVVYFVKSDYLFTLISIVIAIIFGM
                     RARKAESR"
     gene            complement(10001..11347)
                     /gene="albA"
                     /locus_tag="C6W23_RS05880"
                     /old_locus_tag="C6W23_05875"
     CDS             complement(10001..11347)
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="C6W23_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05875"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_106033736.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1052.5, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 1.1e-27,
                     bitscore: 92.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.2e-07, bitscore: 27.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 7.3e-09,
                     bitscore: 31.3, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 5.8e-08, bitscore: 28.1,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 2.4e-44, bitscore:
                     147.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.6e-22, bitscore: 75.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.8e-11, bitscore:
                     38.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 4.5e-09, bitscore: 32.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIERMFPFISESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLN
                     KTAYELCMLMDGQKTAEQILEYQCAAYNESPEDHKDWYYEMLDMLLNKQVIRLTDQPEY
                     RRIATSGSSDFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSLEQFKKTADMLYEK
                     GVLTCEITGGEIFVHPNANELLEYVLKKFKKVAVLTNGTLMRKESLEILRAYKQKIIVG
                     ISLDSVHSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGKDMIHPTKDSEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFDSALVHKLWKAQAPRF
                     SEHCKKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        complement(11054..11332)
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C6W23_RS05880_Subtilosin_rSAM_RRE.1"
                     /evalue="3.60E-29"
                     /identifier="RREFam018.1"
                     /label="C6W23_RS05880"
                     /locus_tag="C6W23_RS05880"
                     /protein_end="98"
                     /protein_start="5"
                     /score="92.0"
                     /tool="antismash"
                     /translation="MFPFISESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLNKTAYE
                     LCMLMDGQKTAEQILEYQCAAYNESPEDHKDWYYEMLDMLLNKQVIRL"
     gene            complement(11479..11610)
                     /gene="sboA"
                     /locus_tag="C6W23_RS05885"
                     /old_locus_tag="C6W23_05880"
     CDS             complement(11479..11610)
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="C6W23_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05880"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 1.8e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       complement(11581..11610)
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="C6W23_RS05885_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11479..11580)
                     /prepeptide="core"
                     /locus_tag="C6W23_RS05885_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[11580:11610](-)"
     misc_feature    complement(11702..11717)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     misc_feature    complement(11729..11743)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.54"
                     /tool="antismash"
     gene            11923..12351
                     /locus_tag="C6W23_RS05890"
                     /old_locus_tag="C6W23_05885"
     CDS             11923..12351
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="C6W23_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05885"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_003326502.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIADDGKEEVIEFRTSGSYHVKQNKVYLSYYE
                     EHDLGKVKTIVKVSESEVFVMRSGAVKMNQRFVPGASTIAKYKMSFGELELTTSTKSIQ
                     SDIGKERGRISIAYDMHVGDEQQHLHNMTITYEGGLDA"
     gene            12348..14018
                     /gene="argS"
                     /locus_tag="C6W23_RS05895"
                     /old_locus_tag="C6W23_05890"
     CDS             12348..14018
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="C6W23_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05890"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_106033737.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEENQIPNVILETPKDKTHGD
                     YSTNMAMQLARIAKKAPRQIAEDIVASFDKGKASIEKLDIAGPGFINFYMDNQYLTKLI
                     PSVLEAGEAYGETNIGNGERIQVEFVSANPTGDLHLGHARGAAVGDSLCNVLAKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKEMPEDGYRGEDIIAIGKRLAKEYGDRF
                     VKEEESERQKFFREYGLKYELEKLRVDLENFRVPFNVWYSETSLYENGKIDKALEALRK
                     QGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYQKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNDNPVYYAQYAHARICSMLRQGEEQGLTP
                     AADLDFSAVNSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASSLHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     misc_feature    complement(14053..14066)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.38"
                     /tool="antismash"
     misc_feature    complement(14054..14067)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.87"
                     /tool="antismash"
     misc_feature    complement(14055..14068)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.25"
                     /tool="antismash"
     misc_feature    complement(14059..14074)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.89"
                     /tool="antismash"
     misc_feature    complement(14071..14086)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            14151..15337
                     /locus_tag="C6W23_RS05900"
                     /old_locus_tag="C6W23_05895"
                     /pseudo=""
     CDS             14151..15337
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="C6W23_RS05900"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05895"
                     /product="nitrate/nitrite transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MINRQNIQLSLQSCSLVAGFMVWVLISSLISQMSSDINLSAGDIS
                     LVTAIPVILGSLLRIPLGYYTNRFGARMTFMISFLLLLFPVFWISIADSVFDLAVGGFF
                     LGIGGAVFSIGVHLFRSIILRKNTVL"
     gene            15449..16165
                     /locus_tag="C6W23_RS05905"
                     /old_locus_tag="C6W23_05900"
     CDS             15449..16165
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="C6W23_RS05905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05900"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_106033738.1"
                     /transl_table=11
                     /translation="MNFLSVRKSDADLLSQDLHQLLESISTKRKIEKNTFLFQEGMDAK
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKNDIVGELTLFTEEPRYMLSAKVLADGEVFV
                     INKNKLEKELVQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VKRSDGILINIALTNHDLAKFCAAARESVNRMLGDLRKQGIISIEESGKIVLHQRDYLR
                     CEIECENCPLDICNID"
     gene            complement(16205..16924)
                     /locus_tag="C6W23_RS05910"
                     /old_locus_tag="C6W23_05905"
     CDS             complement(16205..16924)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="C6W23_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05905"
                     /product="YwiC-like family protein"
                     /protein_id="WP_106033739.1"
                     /transl_table=11
                     /translation="MKVLIPKQHGAWAMLLIPFCLGMVKGGPVLWHIPLFTGWLFLYLT
                     VYPITLAVKKKKTKDYQKWIFYYGIAACCSIIAVVIHKPSFIWLGFSLFPLFLVHVYYA
                     RRKNERALLNDIAGVLFFSTGGLASCWLGAGSLDGWAWFIFAQSSLFFIGSSFYVKSMI
                     REKNNKTFAYCSWGYHLLLPFLSISLGASWGALAFIPSSLRAWFLHGKERSIKTIGILE
                     IVNACFFFAVMCIFLTR"
     misc_feature    16994..17009
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            17069..17545
                     /locus_tag="C6W23_RS05915"
                     /old_locus_tag="C6W23_05910"
     CDS             17069..17545
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014115540.1"
                     /locus_tag="C6W23_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05910"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_010790232.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKHLPMFNQVSLPIVETLLNNGKFIRCSSDQSPSFL
                     HSQSVYIVLKGSIHFIDSRLPEGSRAIAFWKKGDVFPIDQNGELLLSPFISVKTSEDTL
                     VLEIPFYKFKKIMTYHPQLQTNFLVMLQENLFFSYQLFLRYLHTSQDENVTPDS"
     misc_feature    complement(17576..17591)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.74"
                     /tool="antismash"
     misc_feature    complement(17604..17619)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            17685..21371
                     /locus_tag="C6W23_RS05920"
                     /old_locus_tag="C6W23_05915"
     CDS             17685..21371
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042126 - nitrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="C6W23_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W23_05915"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_106033740.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHIQTTYEDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLITMWREALQTHKNPLEAWKSIVEHPEKAKAYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLVEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFFVTLSKEDGAYTAGRFLHAKDIGRQTEHDQWKPAVWNERTNTFAIPQGTMGSRWDG
                     QKKWNLHMADEDTGEQIEPRLSVLGIEDEIGTVRIPYFSNEGNRVLERDLPIKKLNLNN
                     EDVYVTTVFDLILANYGVNRGIGQKSAASFDDAEPFTPAWQEQVTGIKREMVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIANAKDWEGAPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNKNGIDLYKEAEKAGAKTPEDVGAYVAGQLQEKKLKFAIEDP
                     DDEANFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSESIRPEEIKWHDQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAISDLAEEVEMEPVKEAVATPLLHDTMQEMAQPFGKINDWSKGECEAV
                     PGKTMPNIHVVERDYKQIFHKMTALGPNTALKPSGTKGMSWSIADEYESLKKRLGEITT
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLEDITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIRDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    21449..21463
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
ORIGIN
        1 gttatcaatc ttacctaatt taaaataaat ttgtgtaatt aggaaaaagg cttgtggcag
       61 tgaaggaagc attttagatt tttcaaatac atgaatagat ttttttacat actctatcgc
      121 tgattcaaag ctgtgttggt tttgcttgca aagggcaata ttataaagcg ttcttcccat
      181 tagttgcggc tgctgttctg cctcagcaag tgtataagct ttttggaaat gagcaattgc
      241 tttatcatac tgtttcaggt ccaaaaagtt agctccaaac agggactggc attgaatcat
      301 tctgatacca tatgtagttt gttcattgta tatttcaaag gcttgacgtg catagtccat
      361 ggacacataa gtttgcttca tatagtaata aacttctgac attttgaaaa agaattcagc
      421 tttatcaatt ttatctttaa caaaagtcag tttgctctct gcttttttaa aaaattgaat
      481 ggctaatata tattcccgct ggtccagctc atacatacct ctgaagaaat taaaatagta
      541 ttcaagcagt ccggttaaac gagcctgttt tttatcgatt tcaagcagca aatcggacag
      601 tcgcggctgt tcctctatcc gcattttttc taacggttct agatactcaa gcatcagatt
      661 gtgccggaat tccatcagtg aataatacaa atgaagatcc tggtcttctt ctatttgagt
      721 cagctcttgt ttgatttctc ttcgtaagta ttccgcatcc ggtatgctga atcggcgtat
      781 gtacatgtac cattcattaa tcttttctcc aatggaagaa gatatgacgc ctgtcacgtt
      841 tgaaaacccc tcccttcatc attctatata tgtcatattt tatcattttt gttttgtttg
      901 gaagcgcaaa aaaaccgcaa atttttttgc gtgaccgaat agtggaaacg ctctctctct
      961 cccggccata tcaaagcaca ataaaaataa actgttaaac atattggata gggccaattt
     1021 gtttaacagt tcatcatcat attctgcctt tattttgaag atagttcact ttctgttacc
     1081 cacttgtgat ttttcacttt ttctccgcca gttgtcgggg tgtaatcaac cgtatagaca
     1141 gtcgttttct cagctgaatc gattttccct gttgcaccct tcattccctt catatgatcc
     1201 gcttctataa tcacgtccgt tccgggtttt aatgtttcat cactggcatt ttttatttct
     1261 tcttgaatca cccatttatg attttccact cttgttccgc cggttgtcgg tgtataggaa
     1321 acagcatagg ccgtcgtatc ataggcacct gtaatggttg cttcggcacc cttcatgcct
     1381 ttcatgtgat ccgctttgat gatggcttgg cttccaactt tataagttgg gtgctgtgct
     1441 gctgtcaggc cttccggaat ctcactggac tcagaatgag tatgtgtgtc gtccatattc
     1501 atcgtttgat ctgatttttt gtcttgatta tcgctgccgc atgcagacag cattaatagt
     1561 aatagcaaag aaacgattcc gatcaaggtt gtattccttt tcattgtgat cctcctttta
     1621 tttacccaga gaagcttggg aacttatata agtagtgtaa taaggctgct tgtataaata
     1681 aatcctcctt atgaagtctt ttttatttta tataacctga cattcctgct ataaaacata
     1741 atttgtaaat aactcttttt ctttttaccc gttttcagtt aaaaaaaaca cttttggctt
     1801 agaacttttg tacaagcaaa acctttttgt ccccatactc tattactgct gcgcttagca
     1861 gctatttctg agaaggaagt gagcatgtga agaagattga gcgttctttt aaagaaaaag
     1921 ccgtcagaca gcaagaggat tgtttatgtt tttgtgagga agaagccagc cgtgaagcca
     1981 tgtttcaagc gccgatagaa gtgccagagg ggtttgttgt tgatcctgct gaagcggtag
     2041 cgaatgtcac atggaacgcg gacagcctat cctgtgtcag tgaacgctgc ttcattcaga
     2101 ctggacccgg gcctgatgag atcgaaatcc attttgcagt ccgcctgcag ggaaccatca
     2161 cgcttcttgt cagtgtctca cctgtgcgaa accaatatgg acaaggggag ggggctgttt
     2221 ctgtcattca caatgtagag attgatcaag tcgtctatta ctctgatgaa ccggatgatt
     2281 gcccggattt cagtgacatc acgatcgaaa atcttgttgt cgtcccgccg ttttacggca
     2341 gtcctttatc ggtgacagga acgattgtgc tcgccccgga accagagccg gagcctgttt
     2401 atgcgtttac agcgaatcca gatgatcagt cggtttccgt aattgatacg aatactcata
     2461 ccgttataac aaccatttct ctcccatacg agccaacagg tatagaaatt acgccagata
     2521 aagcctctac gtttgttttg catttcaaca atagtgtcat ttctgtcatc gataatggca
     2581 cattgactgt tactggatcc attccgctag atcagccgcc tgaaacaatt aaatttatgc
     2641 ctgaacatga tttcgcatat gttctcgctg gtaatgccat ttatgtgatc agaattgaaa
     2701 cgtctgccgt agaaagatct attcctgttg aagggtatga tattgcaatt gatcccaatg
     2761 ggttgttcgc ctatgttctt gattttggtt tagtgcaaaa agtggactta tctaccggtg
     2821 aagttacagg aatgattgaa cgggagctta ttgtaaattc catagaaaca aagccgccgg
     2881 agcggtatgc ctatgtatta gaacaagatc actttttaaa ttatttgaca gttattgatt
     2941 taaatacgtt taccatcagt aacacccaag agttggagta tgagggtgag tatcaaatgt
     3001 ttaagagcgg atcaggattg tatttgtttg atggtttcac tcacaatcta tattccgtca
     3061 gtccaagtgg tgcaggcgta ataggaaatc ttccgcaatc ggcaagagat tttgcgttta
     3121 ccccgaatgg cgaatttctg tatgcaactc gttttataga gcaaagcatc attgtttaca
     3181 acacggatgg ctattctgtg gaaactgtca tatcgcttgg cgtttcaccg agtgacattg
     3241 cgatttaacc aaatgcatgt tgtgcatttt taaaaggacg tgacattatg aaaaaaaatg
     3301 atctttctgc ttttcaggaa aattgtttct gcttttgtga tgaggagatc agccgagaag
     3361 cgctgtttca agtgccgatt gaagttccgg aggggttcac tattgattct gccgaagcag
     3421 ctgcagcggt tacgtggagt acagacaatt tgtcctgtat cagtgagcct tgcttaatcc
     3481 agactgggcc ggaaccagaa gatatcggtg ttcaatatgc tgtgcgtctg caagggaccg
     3541 ttacgcttct tgtcagtgtc tcacctgtaa gaaatcaata tggacaaggg gacggggctg
     3601 tttctgtcat tcacaatgca gagatcgatc aagtcgtcta ttattctgat aacccggatg
     3661 attgcccgga tttcagtgac atcacgatcg agaaccttgt tgtcgttccg ccgttctacg
     3721 gcagtccttt atcggtgatg gggacgattg tacttgtatc ggcgccggat cagcgatctt
     3781 acgtgtttac tgcaaacact ggagacagca cggtttcggt cattgatact gacgtgaata
     3841 ctcttgtaag taccatttct ttatctgata tcccgactga tctgagtgtt accttggata
     3901 aagcgtatac gtatgttctc cataggaatg cgaatcttgt atcgatcatt aacaacgaaa
     3961 cattaacagt tacacaaacc atccctcttg caggagcccc aagaaaaatc cagtttgaaa
     4021 ctgggggagg atttgcttat attctcgcag ggggcagctc catttatgaa attaatattt
     4081 cctcgcaaac cattaccaat acattcacgg tgtcacccgc tgcggacgat tttgccctag
     4141 accctaacgg acagtttttc tatacgacca actctgtatc ttgggtcgtt aataaatatg
     4201 acataaatac agggcagctg attgatagtt taagtaactt tgaaacacca aatcttattg
     4261 aaaccccgtt aataggggat tttgcttatc tggaaaatgg tgagctaagg ccgaatggcg
     4321 tttctgtgat agatttgaca acatttagcg aatcttcaaa aattaacaga ctgtttgacg
     4381 gtttaataac aattgttttt tctgctgacg gaactcgtgc gtttttcctt gagccctatt
     4441 ttgaggtatt tccggagaat ctcactgtcg tagatacagc gcagcatacc tttataacaa
     4501 ctgcctctct ccccggcgcc tctgacctcg ctgtagcgcc ggacaatcaa tatatctatg
     4561 ttgcacagcc tgcagccaat acagtgacgg tatatcgcac gagtgattat acagccgtag
     4621 cggtcattcc ggttggcgct ggtccgtctg cgatttcgat gtagatgctt ttacaggtcg
     4681 agagaagcag gactgcgata agtgattcgt ttataaacaa gtgatccggt ctgctggatg
     4741 gcagccaaga ggatcagaaa gagcagttcg ctcatggtaa agctgagcat ccaccatatc
     4801 ccggctcctg ctaataacag aacgacagcc tttttagccg tttgtccatt ctggagaagc
     4861 tggagcaggt atgacctcat ataaaacaat aaatagatga tgagaacaat cgcaatcccc
     4921 ttcgtgacag cagggggcgt gtgaaagctg aagggaacgg ctttgaccac ttcaaacatg
     4981 taaccgaaca caatcacttg gcataataca gcccccatca cgtacgtttg gcggatgccc
     5041 ttgtagcttt cgcgcaatga tttcacatcg ccggcataac ggctgcacag cttgcgatgc
     5101 tgaaagtcac agcagctttg atgagattgc gttatcttct gaaaagctgc tgtcatgctt
     5161 ttgacggatc gggtgacata gtgaagatac aaaaatgccg gcagcatcag cacagaagcg
     5221 gcacaagaaa gcaagccgag ccgcacataa tcatttttga tcagctgtac atattgcccc
     5281 gcggcttcag cgctggcttg aaaccagcca aatgaatagg ccgccatgac cataagcagc
     5341 aataacacag tgaagacagt gctttttttc attgtccaac cacctctgga tgagagacat
     5401 gaatggttac ttttttagca gaagccactg tatcaataag atataaaaaa tcctgtacag
     5461 tcatgttttg aatcagccgg taaagctcga aaaaagagca atcataccgc tcacattcag
     5521 ccgcccattc aaagcattta cgcacataat cactgtcata gataatcgcg ttcagcaaag
     5581 attccttgcc gtactccagc caagcttccg cctgacattt ctgctgcatc acatagtatg
     5641 ccgctacatc gatataggct gaagaatgtg cccctttacc gtgaaggatc aaaaagccgc
     5701 catcttctga cacgtgactt tccgctgata agctttggat attaaggagg cgcgtttgcc
     5761 ggatttcttg aaacaacggc gaatctatat gaaaaagaac gcgggagatg atgtcccaat
     5821 acatttgcaa tgtaaaaaga tcgtttttat cggggagtgc gcctatatgt aatccggtcc
     5881 atgtttcccc cgagcactcc gcatcaccca ggctctgatt ttgtaagaag ggagggcatg
     5941 caggcatgaa ttttctcttg gcggtatggc ctgagcggcc gcgcagccgg agatgagaag
     6001 gcaaaatggt ttctgtatct tcagagccgc cgatcagaaa catcgtcata cgctggggct
     6061 ggtagcctgt tgcataggct tcttttagat cattgatcgt taaagcctcg atatcctccg
     6121 ttctgccggc gggaaaaatc gcagcgggag atgcaggaga aagcaaattc agcatctgat
     6181 aatgataatg aagctgttga ttgagatgag ctgtttcaat ttcgctttta atcacgcttt
     6241 tttcttgagc gacaatattc tcgtcaaagg agggattcca taaagcatca agcagtttcg
     6301 ggatcgtgtg ctccagccga tcaggaagag aggtaaacat gaaatttgta tctgtatatg
     6361 tggtgaacgc attcaaaagc gctccatgat caaaaaaatc gctgtataga tttcgcccgt
     6421 tatgccagaa gagaacatgc tctaaaaagt gcgcagtgcc gtacggcagc actttttcgc
     6481 tgtctccgga gtgcaaacgg atgtcccggc tgccgaaatt gactttgaca ttacacagcc
     6541 tcatatgggc gttggggaat tttactctgc atatttttag tccattgtct gcgtacgtga
     6601 tctcggtacg tgcatcaagc tgatgaaaaa aggtttcttt ctccaatctc ctcatcccct
     6661 tactacatgt gctccaatat attcaatatt ggtcacgtat tgtaataaat cgcggcaggt
     6721 aatcgttgaa ataccgtcta gaatgtcttc ttttttgtat gagtaatgac gcagaattcc
     6781 catataggct aagagtcctt ccggagaatc taattgcaga aggatttcat ttttcaggaa
     6841 ttgcttcgct ttttctaatt cctgttcatc tacatgaaaa ttcatgaccg tttcgatcac
     6901 tcttggcgga atctctttct cttgaacgcg atcggtacat acggatacaa gcagcagatt
     6961 gctcataatg tcatagcggg taatgacatg gtaaaccgcc atttgtttct cgcgaaaatg
     7021 tcgaaataat gcggaatggc cgtactttcc gagtaatccg tctatcagct ggatttttat
     7081 ataatcacgg aaaccgttca tttctccgca atcaaaccca agggtcatca cggaaggacc
     7141 tgcggtactg cgtgtctctg tttcataaat gtttttattg acgggttttc ttctaccgtt
     7201 catggaaggt gcgtgtctgg aatatcctcc ggcatgtaac tcttgaacgt ttcctattac
     7261 ataaagctgt ttttgctggg acaacaaatc agttttaaaa tctgatgcat ccagaaagcg
     7321 tttaggctgt atcgcttgta ccttttcttt ccggccaaac atagctgtgc cgtacatcgg
     7381 actgccgaac gtttcctctg ccagacgggc tgccgagtaa gagaaaggat ccgcgaactt
     7441 cttttcgatc ttcagtaaaa ggtcagcctt agccgtttct gcgatatcgg ccggaagaga
     7501 tgccggaaga gaggatctat caacaaacgt ttccagcaca tcatcaatgt tgagattttt
     7561 gtgatatagc ggatgaatca agcgggttcc gtatgtcttg agctgccggt caaaaaatag
     7621 attcgctgag tagataaagc ggctgccggc agcatatcca aagatgtcag tgatgttttg
     7681 ttttagatag gccgccgcac cgtaaaaata gattgtttct tcttcaggct ctgccgcgat
     7741 ttcgatcggt ttcagaaagc tcgcggcgat ggagattgtt gaaaattgat cagtcgttaa
     7801 caggttcatt tccaaatcgt tcactttttc tccttgtatc aaagaaacca ccttcctgtt
     7861 tttgcagcaa atagacaatg atcagcccgg caatcgggat gatcgccaag gagataacag
     7921 tgcccgcgat agttgctaag aataggggaa tacaaaatac gtaggaacga tattttgaga
     7981 agccgctcca gagctgctgt tccgtctgcc acccgaaaga gggtcttttt tcatcagatg
     8041 ttaaccgaat aaaggctccc atcagcagca attcgataca ctgcaaaaaa gtcatgaatg
     8101 aaatcggctg gctgctgatc aaaccgacga tcatagcgat caaaataaac ccgcctgcca
     8161 acaaaccgga ataaaagcga tattttgccc aaaacatcgt tctccgttta atcggaagcg
     8221 tgattaacag catccggtcg tttttttcaa gagaatacaa taaagcgata ggagaacaaa
     8281 ttaacagcaa ggcggtaatc acaatgtaaa tgatatgctg atcagcgatg ccggttttca
     8341 tcatctgaaa cgaaaaaaaa ccgctgaaag ccgccatgac aatgtagttt aataacatcg
     8401 cctttgacga aataaaccga ttccattctc tcttataaaa tgaaaactcc gatgtccgca
     8461 tgaatgaatg catcttgttc tgctgatcag gcacctgcag aaaggagggg aaatcaaaga
     8521 aaacgcccca tgccatgtga accccgcata atgggatcgt caaagcgggc ataaaaacca
     8581 cgctggcgca gatacaggca aatgccgccg catgcagcag gaacacaaat cccttctttt
     8641 tgacaaaaag gttgcttaac agaacgccta ataaaatgga gtagactgtg aaaaacgaaa
     8701 atttgccgag ccaaaataac gtttccgtcc ctgacagcgt gccggttcca aataaaaaca
     8761 acggtaaaat aaaaaagaat aacgttcttc tcaaacaagt atccacaaac aaaaccacgc
     8821 tttgagcaag ccaaaagctc cgtgaagaga ttggcaaaag acagctcagc ttcatgtaag
     8881 attccttcca ttgtgaagaa atggaaagaa ataccatata cacattcata aaaagaagcg
     8941 cgagtgtgac atatgttttt cctaaaaccg actcatcaat gccggcctgc cggatcagtc
     9001 cgatttcaaa caaagccaga acagcaagtc cggcggtgat gcgaatggca tcctttttcc
     9061 cttgccggcc gtaaagctgt ttgaacagca gggtaagaat ttgaaacaca ttattcatgg
     9121 ccgatcacct caaaaaattc ccggcgcaga tctgtgtcat ccttaatagg aatcaatttg
     9181 cgaatctgtt tatcatgaag aatagctgca taatggcaaa accttttcac cacatcaagc
     9241 agatgggaag aaaacaaaat ggttccgcct gccttgcaat actcctgcat tttctcataa
     9301 aagacttcaa tcgattccac gtccaagccg acaagcggct catctaaaat aaacagggga
     9361 gcccgcagca ataaccctgt cagcagaaca accttttgcc tgttgccgag agacagctct
     9421 gagattctcc gattcgtgta ctgagaaaag tgaaactcct ctgctaaact gacatattgt
     9481 tgttcgtgaa attctttttg ataaagagaa tggacgaaag aaacgtattc cttcgccgtg
     9541 atctctgtaa aaagcaatgg ataatccgcc gcgaagtagc ggttggtttt cagctgatct
     9601 aatgtcttca gcggagtttt ggcgttaact tcaatgccgc acagcttgaa gctcccgcta
     9661 aaattccgat taacgcctgt cagcgtattg atcagcgttg ttttgccggc gccatttact
     9721 ccaagcagtc cgtaaacgtc gcctttttct aaatgtaaat caacgttttc taagatgacg
     9781 ttatcttgtt cgtaccaaac agataaagcg tgtatatcca acatgctcat cgagattcag
     9841 ccttccgcgc tctcattccg aatataatgg caatcacaat ggagatcaga gtaaacaaat
     9901 aatcgctttt gacgaaatag acaaccgcgc cgatgacaaa cacgaatgaa aggatataca
     9961 atagccattt tctttgtgtt ggtgacaaaa catttccctc ctaaataagc tggacaacat
    10021 cttctaattg ttcatttttc gcccaggaac agatattttt acggtgatat ttgttagagt
    10081 ttaagccttt taagtaacag cctccgcaat agccgctgaa tgggcatttg tctttcttgc
    10141 aatgctcgct gaaccgcggc gcctgcgctt tccatagttt atggacgaga gcggaatcaa
    10201 agatgctttc atatgaatca tgaaagatat ttcccaatga aaattccttc gggaagagcg
    10261 cgcacgggcg tacttctccg aacgggctga tcacaattga tttccagcct gcgccgcaat
    10321 tcgccgcacg ttttctctca taagggataa tcggaatcag atccttaaat tcatcaatga
    10381 cattttgctc gtactccata aatttgcggt gctgctcgga atctttcgtc gggtggatca
    10441 tatccttgcc tcttccgaaa tcatcaaccc aattgtaaga gaaggctttc gcaccaagat
    10501 cgcgcacctt ttgggccatg tcatgaattt cccacatatt tttctcgaaa accgacatgg
    10561 cgactctgac aaaaataccg tgatcactca ataattttat cgttttacag gtttgggcaa
    10621 aagagccttt tctccctcta aaggaatcgt ggacttcaga atggacactg tccagtgaaa
    10681 taccgacgat gatcttttgc ttgtatgctc ttaaaatctc caggctttct tttcgcatca
    10741 gcgtcccgtt tgttaagacg gcaacctttt taaatttctt taatacatac tcaaggagtt
    10801 cattggcgtt cgggtggaca aaaatctctc cgcccgttat ttcacatgtt aaaacgcctt
    10861 tttcgtacag catatccgct gttttcttga attgttcaag agataccgtt cccagcgctt
    10921 caggcgagct ttctaaataa cagtgggcgc attttaaatt acagcggtga gtcagctcaa
    10981 aggtcgcatg cagcggcatc ggaaagtcgc tgctcccgct tgtggcaatg cgccgatatt
    11041 cgggctggtc tgtaagccga atgacctgct tgttcagcag catgtcgagc atttcataat
    11101 accaatcctt gtggtcttcg ggagattcat tgtacgccgc gcattggtat tctaatattt
    11161 gttctgccgt tttttgcccg tccatcagca tacaaagctc gtacgccgtt ttattgagat
    11221 ccaagtattc aaaatcagag atcgagacat tatcacgcat ataatcaatt tctaatactc
    11281 cgccctcagg aagctggtga actcttacac tttcactgat aaatggaaac atccgctcta
    11341 taagcaaaaa taccatctcc tatacatatg atacaaataa tgagaaaaca tgtatgtata
    11401 actaaggagt agatagaaag taaaaatact tttcaaaaag aggcacagta atttactatg
    11461 cctcttttag gaaatgcttt atccccataa accgaatagc cctgttgcac ctgcgatttc
    11521 aaagtctgga ataggtccgt ccactaaaca agcagctccg attgaacatg ttgcacaacc
    11581 tttgttttct acaatgacag cttttttcat aatagaaatc ctcccttgtt taatttttct
    11641 agcatatctc tgatgtaatt taatcttaaa actatcaaaa taccttttca atatgtatat
    11701 tttgaagaaa atgtgaaaaa tattagatag atttcagaaa aatgtaacat tcaaaacggc
    11761 attaatttct atttaaatgc tcttcttctc attaatcgct ttttatgagg tttatcttca
    11821 aaactgatga gtaatgatgg taagatagaa gcagttgaac tttaaatagc gaatgattat
    11881 actattcaag tcaaagtgga atgatgaaaa ggacgtgtca gcatgaaaca agagacaccg
    11941 ataacgctcc atgtaaaatc tgtgattgcg gatgacggga aagaagaggt cattgagttc
    12001 cgcacctccg gatcttatca tgtgaaacaa aataaagtgt atctttctta ttatgaagaa
    12061 cacgatttgg gcaaagtgaa aacgattgtg aaagtaagcg agagcgaagt gtttgtcatg
    12121 aggtcaggcg cagtgaaaat gaatcagcgg tttgtgccgg gagcctctac cattgccaaa
    12181 tataaaatgt catttggcga gcttgagctg actacaagca caaaatcgat tcagtctgac
    12241 atcggcaaag aaagaggccg tatcagcata gcttatgata tgcatgtggg agacgaacag
    12301 cagcatttac ataatatgac gatcacgtat gagggaggac ttgacgcatg aacattgcgg
    12361 aacaaatgaa ggacgtgctg aaagaggaaa ttaaagcagc cgttctgaaa gcgggattgg
    12421 ctgaagaaaa ccagattcca aatgtcattt tagagacacc gaaagataaa acacatggtg
    12481 attattcaac gaacatggcg atgcagctgg caagaatcgc aaaaaaagcc ccgcgccaaa
    12541 tcgctgagga tattgtagct tcttttgata aaggaaaggc ttcaattgaa aagcttgata
    12601 tcgcaggccc tggatttatc aatttctata tggataatca atatttaacg aagctgatcc
    12661 catctgtatt ggaagcggga gaagcatacg gggaaacaaa tatcggaaac ggcgagcgca
    12721 tccaagtgga attcgtatct gcgaatccga cgggcgatct tcatttaggc catgcgcgcg
    12781 gagcagccgt cggcgattct ctgtgcaatg tgctggctaa agccggatat gatgtgagcc
    12841 gcgaatatta tatcaatgac gcgggaaatc agatcaacaa cttggcgctt tctgtcgaag
    12901 tccgttactt tgaagcgctc ggccttgaaa aagaaatgcc tgaggacgga taccgcggcg
    12961 aggatattat cgcaatcggg aagcgtctcg ctaaagaata cggagaccgc tttgtcaaag
    13021 aagaagagag cgaaagacag aagttcttcc gcgaatacgg cttgaagtat gagttggaaa
    13081 agcttcgtgt agacttagaa aacttccgcg tgccgtttaa tgtctggtat tctgaaacgt
    13141 cattatacga aaacggaaaa atcgacaaag cgctcgaagc gctgcgcaaa caaggccacg
    13201 tgtatgaaga agacggcgca acttggttcc gctcaacaac attcggcgat gacaaagacc
    13261 gtgttttgat taaaaaagac ggcacttaca cttatttgct gcctgatatc gcttaccata
    13321 aggacaagct agaccgcgga ttcgataagc tgatcaacgt ctggggcgca gatcaccacg
    13381 gctatattcc gcggatgaaa gcggccattg aggcgcttgg ttatcaaaaa ggaacgttag
    13441 aagtagaaat tattcagctc gtccatctat ataaaaacgg cgagaaaatg aaaatgagca
    13501 agcgtacagg aaaagcggta acgatgcgtg acttaattga agaagtcggc ttagacgccg
    13561 tccgttattt cttcgcgatg cgcagtgccg atacacatat ggattttgac ttggatcttg
    13621 cggtgtccac ttcaaatgac aatccggtgt attacgcgca atacgctcac gcgagaatct
    13681 gcagcatgct tcgccaagga gaagagcagg gattaacgcc tgcggctgat cttgacttta
    13741 gcgccgtcaa ttctgaaaaa gaatacgatt tgctgaaaac gatcggcggc ttccctgaag
    13801 cagtggcgga agcggcggaa aaacgcattc cgcaccgcgt gacgaactat atttatgact
    13861 tggcatcttc tctgcacagc ttctataatg cggaaaaggt aatcgatcct gaaaatgaag
    13921 agaaaagccg cgcacgctta gctttaatga aagcaaccca aatcacgctg aataatgcgc
    13981 ttcagttgat tggcgtttcg gctcctgaaa aaatgtaatg aagatgaaag gacaaagccc
    14041 cgggctttgt ccttttttgt taaaaaaacg tgtgatgtac ttcacaatcc tattcaccga
    14101 gtttttgtat gataagactg attattgaat cattgaaagg ggcaagccga atgattaacc
    14161 gtcaaaacat tcaattatcg ttacagtcat gcagcttggt ggcaggattt atggtttggg
    14221 ttttgatttc ttcattaatt tctcaaatgt catctgatat taatttgagc gccggcgaca
    14281 tttcgctggt tacggccata cctgtcattc tgggatcgct tctccgcatt cctttgggat
    14341 attacacgaa caggtttggc gcgcggatga cttttatgat cagctttcta ttgcttttgt
    14401 ttcctgtgtt ttggatcagt atcgcagatt ctgtgtttga tttggccgtg ggcggttttt
    14461 tcttggggat tggaggagcg gttttctcca ttggggtgca tctcttccga agtattatcc
    14521 taaggaaaaa cacggtttta taaacggcat ttacggcgct ggaaatatcg gaaccgccat
    14581 cacaacgttt gcagctcctg ttgttgctca atctgtggga tggaagagta cggtgcaaat
    14641 gtatatggtc ctgctggctt tatttgcttt gctgcacttt ttcctgggcg atcgaaacga
    14701 gaagaaagtc aaagtttccg taaaggttca aataaaagcc gtttaccgaa atcatctgtt
    14761 gtggttctta agcctttttt attttataac atttggcgcg ttcgttgcct ttaccattta
    14821 tcttcctaat tttcttgttc agcactttgg tcttagtcct gtggatgccg ggtttagaac
    14881 ggcaggtttt attgctgtgt ccacgcttct cagacctgtt ggcggatttt tggcagataa
    14941 agtgagtccg cttagaatgt taatgtacgt cttcgcgggt ctgacattat cgggcattat
    15001 cttgtcgttc tcaccgagtc tcggcattta cgcttttggg gcgttaacag ttgctgtctg
    15061 ctcaggaatt ggaaacggaa cagtttttaa attggtgcct ttttatttct caaaacaagc
    15121 gggaattgca aacggtattg tttccgccat ggggggattg ggaggattct ttccgccgct
    15181 gatcctggca agcgtatttc aagcgacagg acaatatgca atcggattta tggcgctctc
    15241 ggaagctgct ttagccagct ttgttattgt catttggatg tattggcagg aaaggatgaa
    15301 aacgcacact gagagaaatg ggcacagcgt aaactaatgg gaagccggcg tttggggaat
    15361 tcacgagatt gtaagttttt ttaaaatgat gcaaatcgat tcacgttaca atagaaatac
    15421 acaacgtgac tatcttcgag gtgagctcat gaattttctc tctgttcgaa aatctgatgc
    15481 agatcttctc tcacaagatc tgcatcaatt gctggaatca atcagtacaa aaagaaaaat
    15541 tgaaaaaaac acgtttctct ttcaagaagg aatggatgca aaagagcttt atctgattca
    15601 atcaggactc attgaaattg gcaaactgac gtctgacggc aaggatctga cgcttaggat
    15661 ctgccaaaaa aatgatattg tcggggaatt aacacttttt acagaagaac cgagatatat
    15721 gctgagtgca aaagtgttag cagacggtga agtgttcgtc atcaataaaa acaaactgga
    15781 aaaggaattg gttcaaaacg gtgctttgac atttgaattt atgaaatgga tgagcaccca
    15841 cctgcgaaaa attcagtcca aaatccgtga ccttcttctt catggcaaaa aaggggcgct
    15901 ttattccaca ctcattcgtt tgtcaaatag ctatggggtg aaacgaagcg acggaattct
    15961 tataaacatt gcactgacga accatgattt ggcgaagttt tgtgcggctg caagagagag
    16021 tgtcaatcgc atgctgggtg atcttcgtaa acaaggaatc atttcaattg aggaatccgg
    16081 aaagattgtt ttgcatcagc gggactattt aagatgtgaa attgagtgcg aaaattgccc
    16141 gctggatatt tgcaatatcg attaatcaag aaataaacaa ggactgcaaa cttcagtcct
    16201 tgttttatct tgttaaaaaa atacacatga ctgcgaaaaa gaagcacgcg ttcacgattt
    16261 caagaatgcc gatcgtctta atagatcgct cctttccgtg taagaaccat gctctcaaac
    16321 tgcttggaat aaaagcgaga gccccccagc ttgctccgag agatatagaa agaaagggaa
    16381 gaagcaggtg atatccccat gaacagtatg caaatgtttt gttgtttttc tcccggatca
    16441 tagacttcac ataaaaggaa cttccgataa aaaataagct ggattgcgcg aaaataaacc
    16501 atgcccagcc gtcaaggctt cccgccccca gccagcagct ggcaagtccg cctgtactaa
    16561 agaacaagac tcccgcaata tcattcagaa gcgctctttc gtttttgcgg cgggcataat
    16621 agacatgaac gaggaacagc ggaaacaaag aaaagccgag ccagatgaac gaaggcttat
    16681 ggatgacaac ggcaatgata gagcagcaag ctgcaatgcc gtaataaaaa atccattttt
    16741 gatagtcttt tgtttttttc tttttcactg ccaaggtaat ggggtaaacg gttaaataga
    16801 gaaatagcca gcccgtaaat agcgggatat gccatagaac gggacctccc ttcaccatac
    16861 cgaggcaaaa cggaatcaac agcatagccc atgcaccgtg ctgcttcgga atgagcacct
    16921 tcattgaaac actcctttct gtttcattat aaaagcaatc attcttccga taagtgacat
    16981 ttatcataat ttctgtgaat tacatcactg ctgtgttgat tcaaccaaga tacactaaag
    17041 ctatccttat ctctcaggag gctttcctat gaatcagtgt gactatttat tatttctgaa
    17101 acatcttcca atgtttaatc aagtatctct tcccattgtc gaaacattgc tgaataacgg
    17161 gaagttcatc cgttgctcat ctgatcagtc tccatctttt ttgcattcac aatcagttta
    17221 tattgtatta aaaggcagca ttcattttat tgacagcaga ctgcctgaag gatcgcgcgc
    17281 cattgcattt tggaaaaaag gtgatgtgtt ccccattgat caaaatggcg agctgctttt
    17341 atctcctttc atttcagtca aaacatctga agacacactc gtgttggaaa ttccttttta
    17401 caaatttaaa aaaataatga cctatcatcc gcagctgcag acgaattttc tggtcatgct
    17461 tcaggaaaat ctcttttttt cctaccagtt atttttgcgt tatctgcaca catctcagga
    17521 tgaaaacgtc actcccgatt cctaaccagg aatcgggttt ttttgaatcc tgaatgtgaa
    17581 aaatttgtga aataaggggc gtatgtgaca aagttcacaa ggaacgatgc tgcctctgta
    17641 tatagtgaaa tgagaatcac ctgactcaaa ggagtgaagc atcgatgaaa aagaagaaaa
    17701 tgagtccgct gttcaggaga ctaaactatt tctctcctat tgagcatcat tctaataaac
    17761 atattcaaac aacatacgaa gatcgcgatt gggagaatgt atatagaaac agatggcagt
    17821 acgataaagt tgtccgctcc acccacggag tcaactgcac gggatcttgc agctggaata
    17881 tttatgtgaa aaacggcatc gtcacgtggg aagggcaaaa tttgaattat ccttcaaccg
    17941 gccctgatat gcctgacttc gagccaaggg gctgtccccg cggggcaagt ttttcctggt
    18001 atatctacag cccgctgcgt gtcaaatatc catacgttcg cggtgtgctg attactatgt
    18061 ggcgggaagc attgcaaaca cacaaaaatc cattggaagc atggaaatct atcgttgagc
    18121 atccggaaaa agcgaaggcc tataaacagg cgagaggaaa aggcggtttt gtgcgcgctg
    18181 agtggccgga ggtgctgaaa ctgatttctg cttctctatt atatacagtc atgaaatacg
    18241 gccctgaccg taacgtcgga ttttctccga ttcccgccat gtcaatgatc agccacgcgt
    18301 caggctcgcg gtttatgtca ttaatcggcg gccctatgct gagcttttat gattggtatg
    18361 cggatcttcc cccagcgtct ccgcaaatct ggggagacca gacagacgtg ccggaaagca
    18421 gtgactggta caattcgggc tatatcatca catgggggtc caatgtaccg ttaacaagaa
    18481 cgccggatgc acactttttg gtagaagccc gctataaagg ggcaaaagtc atctcaatta
    18541 gtccggattt tgcggaatcg tcaaaatttg cggatgactg gctgagcatc cgtcagggaa
    18601 cagacggcgc gcttgcgatg gcaatggggc atgtcatcct gcaagaattt tacgtgaatc
    18661 aagaaacaga gcgcttcata gagtacgcaa agcaatacac agatttcccg ttctttgtca
    18721 ccttgtcaaa agaagatggc gcttatacag ccggacgttt tctccatgcg aaggacatcg
    18781 gacggcaaac agagcatgat cagtggaagc ctgctgtgtg gaatgaacgt acaaacacat
    18841 ttgcgatacc gcaaggaaca atgggatcac gatgggacgg ccaaaagaaa tggaatctgc
    18901 acatggcaga tgaagataca ggggaacaaa ttgaaccgag gctgtcagtg ctcggaatag
    18961 aagacgaaat cggcacagtt cgaatccctt atttctcaaa tgagggaaac agagtgcttg
    19021 agcgcgatct tcccattaag aaactaaacc tgaataatga agacgtatat gtcacaaccg
    19081 tttttgattt aattctggca aactatggcg tcaatcgggg aatcgggcag aaatcagccg
    19141 cctcgtttga tgatgctgag ccgtttacac ccgcctggca agaacaggtg acaggaatca
    19201 aaagggagat ggtcgttaaa attgccagag aatttgccca aaatgcgatc gatacagacg
    19261 gacggtcaat gattatcgtg ggggcgggaa ttaaccattg gttcaactct gacacgattt
    19321 accgggcggt tttaaatctt gttttattag tcggcgccca aggtgtaaac gggggcggat
    19381 gggctcacta tgtcgggcag gaaaagcttc gcccggctga aggctggcag acgattgcca
    19441 atgcaaagga ttgggagggg gcgccaaagc tgcaaaacgg cacatcattc ttctactttg
    19501 cgacagacca gtggcgctac gaggatcagc cgatcagtga cttggcttct ccgatcgcag
    19561 catcctcccg ctacaagcat cacgccgact acaacgtgct ggcggcaaga ttagggtggc
    19621 tcccgtctta cccgacgttt aataaaaacg gaattgatct ttacaaggaa gctgaaaaag
    19681 cgggtgcaaa aacgcctgaa gatgttggtg catatgtggc cggtcagctc caagaaaaaa
    19741 aactgaaatt tgccattgaa gatcctgacg atgaagccaa tttcccgaga aatctttttg
    19801 tatggagagc gaatctgatc tcaagttcgg gaaaagggca tgaatatttt cttaagcatc
    19861 tcttggggac gacaaatgga ttgatgaatg acgacagcga gagcatccgt ccggaagaaa
    19921 tcaaatggca tgatcaagca ccggaaggaa agctcgactt attaatcaat ctcgattttc
    19981 gaatggctgg aacggcattg tattccgata tcgtgcttcc ggcggcgact tggtatgaaa
    20041 aacatgatct cagcagtacg gatatgcatc cgtttattca tccttttgct ccggccatct
    20101 cagcgccttg ggaatccaag tcagactggg atatttttaa agcattatca aaagccatat
    20161 ccgacttggc tgaagaagta gagatggagc cggttaaaga agctgtcgcg acgccgctcc
    20221 tccatgacac tatgcaggaa atggcgcagc ctttcggaaa aatcaatgac tggagcaaag
    20281 gcgaatgcga agccgttccg gggaaaacga tgccgaacat tcatgttgtt gaacgggact
    20341 ataaacaaat ctttcataaa atgaccgcac tcggccctaa caccgcccta aaaccgagcg
    20401 gaacaaaagg gatgagctgg tcgatagccg atgaatatga atcactcaaa aagagactgg
    20461 gagaaatcac aacggacagc gtcgccaagg gatgtccgaa tataagtgag gcgaagcagg
    20521 cggcagaagc cattttaacc ctttcttcca cttcgaatgg aaaagttgcg gtgaaagcat
    20581 gggaatcact tgaagacatc acaaacctga agctgaaaga tttggctgaa gagcgggaag
    20641 aagaatgctt tacgttcgaa caaatcaccg ctcagccaaa aacggtcatc acgtctccgg
    20701 catttacagg ctcagaaaaa ggggggcgca ggtactcgcc gtttacgaca aatgtagaaa
    20761 aattaatccc ttggcggacg ctgacgggca gacagtctta ctatgtcgat catgagctga
    20821 tgatggagtt cggggaaacg atggcgacat ttaaaccgat cctccagcat cgtccgtttc
    20881 tgagtaaacg gcctgatcaa gagggcaaag aaatcgttct caattattta acgccgcata
    20941 acaaatggtc cgtccacagc atgtactttg actcattacc gatgctgacg ctattccgcg
    21001 gagggccgac agtgtggatg aataaagatg atgcagagga cacagatatc agagataacg
    21061 attggattga atgcttcaac cgaaatggcg ttgtcgtagc gagagccgtt ctttctcacc
    21121 gtattcctaa agggatggcg tttatgcacc atgcacaaga ccgccacatc aacgtacccg
    21181 gcacaaaact gacgaataac cgcggcggca cccataacag cccgacaagg attcatgtta
    21241 aaccgacaca aatgatcggc ggctatgctc agcttagcta cggatttaat tactacggcc
    21301 caacggggaa tcagcgtgat ctgaatgtgg tcatccgcaa gctgaaggag gtcgattggc
    21361 ttgaagatta aagcgcaaat cggaatggtc atgaatttag ataaatgcat cggctgccac
    21421 acatgcagcg tgacctgcaa aaacacgtgg acaaaccgtt ccggagcgga atatatgtac
    21481 ttcaataatg ttgaaacaaa acctggcatc ggctatccga agcagtggga ggaccaagac
    21541 aaatataaag gcggctggac attaaaaaaa ggaaagcttg agctgaaatc aggaccgaaa
    21601 accaaccgtc
//
