LOCUS       NZ_PVQM01000002        21610 bp    DNA     linear   CON 06-NOV-2024
DEFINITION  Bacillus atrophaeus strain GBSC56 NODE_2_length_679098_cov_39.9084,
            whole genome shotgun sequence.
ACCESSION   NZ_PVQM01000002
VERSION     NZ_PVQM01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus atrophaeus
  ORGANISM  Bacillus atrophaeus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus.
REFERENCE   1  (bases 1 to 679098)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Genotypic and phenotypic analysis of antagonistic Bacillus spp.
            isolated from rhizosphere soil of plants in Tibet
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 679098)
  AUTHORS   Borriss,R., Lasch,P., Wu,L., Wu,H. and Gao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAR-2018) UG, NordReet, Marienstr. 27a, Greifswald
            17489, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. A5-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 39.4x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002998055.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 02:04:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,249
            CDSs (total)                      :: 4,157
            Genes (coding)                    :: 3,986
            CDSs (with protein)               :: 3,986
            Genes (RNA)                       :: 92
            rRNAs                             :: 7, 8, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 1 (5S, 23S)
            partial rRNAs                     :: 8, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 171
            CDSs (without protein)            :: 171
            Pseudo Genes (ambiguous residues) :: 0 of 171
            Pseudo Genes (frameshifted)       :: 105 of 171
            Pseudo Genes (incomplete)         :: 120 of 171
            Pseudo Genes (internal stop)      :: 23 of 171
            Pseudo Genes (multiple problems)  :: 68 of 171
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:35:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 656070
            Orig. end                         :: 677680
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVQM01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21610
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="3"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21610
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21610
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11610](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11610
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(147..161)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(239..3925)
                     /locus_tag="C6W22_RS11455"
                     /old_locus_tag="C6W22_11445"
     CDS             complement(239..3925)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042126 - nitrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="C6W22_RS11455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11445"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_106047183.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHSQTTYEDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLITMWREALQTHKNPLEAWKSIVEHPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIDYAKQYTD
                     FPFFVTLSKEDGAYTAGRFLHAKDIGRQTEHDQWKPAVWNERTNAFAIPQGTMGSRWDG
                     QKKWNLHMADEDTGEQIEPRLSVLGIEDEIGTVRIPYFSNEGNRVLERDLPIKKLNLNN
                     EDVYVTTVFDLILANYGVNRGIGQKSAASFDDAEPFTPAWQEQVTGIKREMVVKIAREF
                     AQNAIDTDGRSMIILGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIANAKDWEGAPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNKNGIDLYKEAETAGARTTKDVADYVARQLQEKKLKFAIEDP
                     DDEANFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSESIRPEEIKWHDQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAISDLAEEVEMEPVKEAVATPLLHDTMQEMAQPFGKINDWSKGECEAV
                     PGKTMPNIHVVERDYKQIFHKMTALGPNTALKPSGTKGMSWSIADEYESLKKRLGEITT
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLEDITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIRDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3991..4006)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    4019..4034
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.28"
                     /tool="antismash"
     gene            complement(4065..4541)
                     /locus_tag="C6W22_RS11460"
                     /old_locus_tag="C6W22_11450"
     CDS             complement(4065..4541)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014115540.1"
                     /locus_tag="C6W22_RS11460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11450"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_106047184.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKHLPMFNQVSLPIVETLLNNGKFIRCSSDQSPSFL
                     HSQSVYIVLKGSIHFIDSRLPEGSRAIAFWKKGDVFPIDQNGELLLSPFISVTTSHDTL
                     VLEIPFCKFKKIMTYHPQLQTNFLVMLQENLFFSYQLFLRYLHTSQDENVTPDS"
     misc_feature    complement(4601..4616)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4686..5406
                     /locus_tag="C6W22_RS11465"
                     /old_locus_tag="C6W22_11455"
                     /pseudo=""
     CDS             4686..5406
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="C6W22_RS11465"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11455"
                     /product="YwiC-like family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKVLIPKQHGAWAMLLIPFCLGMVKGGPVLWHIPLFTGWLFLYLT
                     VYPITLAVKKKKTKDYQKWIFYYGIAACCSIIAVVIHKPSFIWLGFSLFPLFLVHVYYA
                     RRKNERALLNDIAGVLFFSTGGLASCWLGAGSLDGWAWFIFAQSSLFFIGSSFYVKSMI
                     REKNNKTFAYCSWGYHLLLPFLSISLGASWGGSRFYSKQFESMVLTRKGAIY"
     gene            complement(5446..6162)
                     /locus_tag="C6W22_RS11470"
                     /old_locus_tag="C6W22_11460"
     CDS             complement(5446..6162)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="C6W22_RS11470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11460"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_003326506.1"
                     /transl_table=11
                     /translation="MNFLSVRKSDKDLLSQDLHQLLESISTKRKIEKNTFLFQEGMDAK
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKNDIVGELTLFTEEPRYMLSAKVLADGEVFV
                     INKNKLEKELVQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VKRSDGILINIALTNHDLAKFCAAARESVNRMLGDLRKQGIISIEESGKIVLHQRDYLR
                     CEIECENCPLDICNID"
     gene            complement(6274..7461)
                     /locus_tag="C6W22_RS11475"
                     /old_locus_tag="C6W22_11465"
     CDS             complement(6274..7461)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="C6W22_RS11475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11465"
                     /product="NarK/NasA family nitrate transporter"
                     /protein_id="WP_003326505.1"
                     /transl_table=11
                     /translation="MINRQNIQLSLQSCSLVAGFMVWVLISSLISQMSSDINLSAGDIS
                     LVTAIPVILGSLLRIPLGYYTNRFGARMTFMISFLLLLFPVFWISIADSVFDLAVGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGFINGIYGAGNIGTAITTFAAPVVAQSVGWKSTVQ
                     MYMVLLALFALLHFFLGDRNEKKVKVSVKVQIKAVYRNHLLWFLSLFYFITFGAFVAFT
                     IYLPNFLVQHFGLSPVDAGFRTAGFIAVSTLLRPVGGFLADKVSPLRMLMYVFAGLTLS
                     GIILSFSPSLGIYAFGALTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEAALASFVIVIWMYWQERMKTHTERNGHSVN"
     misc_feature    complement(7526..7541)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    7543..7556
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.39"
                     /tool="antismash"
     misc_feature    7544..7557
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.87"
                     /tool="antismash"
     misc_feature    7545..7558
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.38"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="C6W22_RS11480"
                     /old_locus_tag="C6W22_11470"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="C6W22_RS11480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11470"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_106047185.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLADESQIPNVILETPKDKTHGD
                     YSTNMAMQLARIAKKAPRQIAEDIVASFDKGKASIEKLDIAGPGFINFYMDNQYLTKLI
                     PSVLEAGEAYGETNIGNGERIQVEFVSANPTGDLHLGHARGAAVGDSLCNVLAKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKEMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VKEEESERQKFFREYGLKYELEKLRVDLENFRVPFNVWYSETSLYENGKIDKALEALRK
                     QGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYQKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNDNPVYYAQYAHARICSMLRQGEEQGLTP
                     ASDLDFSAVNSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLAASLHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /locus_tag="C6W22_RS11485"
                     /old_locus_tag="C6W22_11475"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="C6W22_RS11485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11475"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_010790235.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIADDGKEEVIEFRTSGSYHVKQNKVYLSYYE
                     EHDLGKVKTIVKVSESEVFVMRSGAVKMNQRFVPGVSTIAKYKMSFGELELTTSTKSIQ
                     SDIGKERGRISIAYDMHVGDEQQHLHNMTITYEGGLDA"
     misc_feature    9868..9882
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.54"
                     /tool="antismash"
     misc_feature    9894..9909
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="C6W22_RS11490"
                     /old_locus_tag="C6W22_11480"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="C6W22_RS11490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11480"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 1.5e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="C6W22_RS11490_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="C6W22_RS11490_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10264..11610
                     /gene="albA"
                     /locus_tag="C6W22_RS11495"
                     /old_locus_tag="C6W22_11485"
     CDS             10264..11610
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="C6W22_RS11495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11485"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_106047186.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1054.9, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 9.2e-28,
                     bitscore: 91.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.9e-08, bitscore: 28.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 4.7e-08,
                     bitscore: 28.4, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 4.8e-08, bitscore: 28.1,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 6.6e-44, bitscore:
                     145.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.2e-22, bitscore: 75.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.5e-11, bitscore:
                     38.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.6e-09, bitscore: 32.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIEQMFPFISESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLN
                     KTAYELCMLMDGQKTAEQILECQCATYNESPEDHKDWYYEMLDMLLNKQVIRLTDQPEY
                     RRIATSGSSDFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSLEQFKKTADMLYEK
                     GVLTCEITGGEIFVHPNANELLEYVLKKFKKVAVLTNGTLMRKESLEILRAYKQKIIVG
                     ISLDSVHSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFDSALVHKLWKAQAPRF
                     SEHCKKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10279..10557
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C6W22_RS11495_Subtilosin_rSAM_RRE.1"
                     /evalue="3.70E-29"
                     /identifier="RREFam018.1"
                     /label="C6W22_RS11495"
                     /locus_tag="C6W22_RS11495"
                     /protein_end="98"
                     /protein_start="5"
                     /score="91.9"
                     /tool="antismash"
                     /translation="MFPFISESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLNKTAYE
                     LCMLMDGQKTAEQILECQCATYNESPEDHKDWYYEMLDMLLNKQVIRL"
     gene            11623..11784
                     /locus_tag="C6W22_RS11500"
                     /old_locus_tag="C6W22_11490"
     CDS             11623..11784
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="C6W22_RS11500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11490"
                     /product="bacteriocin biosynthesis protein AlbB"
                     /protein_id="WP_003326500.1"
                     /transl_table=11
                     /translation="MSPTQRKWLLYILSFVFVIGAVVYFVKSDYLFTLISIVIAIIFGM
                     RARKAESR"
     gene            11781..12500
                     /locus_tag="C6W22_RS11505"
                     /old_locus_tag="C6W22_11495"
     CDS             11781..12500
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="C6W22_RS11505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11495"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_106047187.1"
                     /transl_table=11
                     /translation="MSMLDIHALSVWYEQDNVILENVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGSFKLCGIEVNAKTPLKTSDQLKTNRYFAADYPLLFTEITAKEYVS
                     FVHSLYQKEFHEQQYVSLAEKFHFSQYTNRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYEKMQEYCKAGGTILFSSHLLDVVKRFCHYAAILHDKQIRKLIPI
                     KDDTDLRREFFEVIGHE"
     gene            12493..13821
                     /locus_tag="C6W22_RS11510"
                     /old_locus_tag="C6W22_11500"
     CDS             12493..13821
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326498.1"
                     /locus_tag="C6W22_RS11510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11500"
                     /product="bacteriocin biosynthesis protein AlbD"
                     /protein_id="WP_106047188.1"
                     /transl_table=11
                     /translation="MNNVFQILSLLFKQLYGRQGKKDAIRITAGLAVLALFEIGLIRQA
                     GIDESVLGKTYVTLALLFMNVYMVFISVSSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGTGTLSGTETLFWIGKFSFFTVYSILLGVLLSNLFVKKKG
                     FVFLLHAAAFACICASVVFMPAVTIPLCGVHMAWGVFFDFPSFLQVPHQQNKMHSFMRT
                     SEFSFYKREWNRFISSKAMLLNYIVMAAFSGFFSFQMMKTGIADQHIIYIVITALLLIC
                     SPIALLYSLEKNDRMLLITLPIKRRTMFWAKYRFYSGLLAGGFILIVMIVGLISSQPIS
                     VMTFLQCIELLLMGAFIRLTSDEKRPSFGWQTEQQLWSGFSKYRSYVFCIPLFLATIAG
                     TVISLAIIPIAGLIIVYLLQKQEGGFFDTRRKSERFGNEPVND"
     gene            13769..14956
                     /locus_tag="C6W22_RS11515"
                     /old_locus_tag="C6W22_11505"
     CDS             13769..14956
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326497.1"
                     /locus_tag="C6W22_RS11515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11505"
                     /product="insulinase family protein"
                     /protein_id="WP_106047189.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 7.5e-07,
                     bitscore: 24.7, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQGEKVNDLEMNLLTTDQFSTISIAASFLKPIENAAEPEEETIY
                     FYGAAAYLKQNITDIFGYAAGSRFIYSANLFFDRQLKTYGTRLIHPLYHKNLNIDDVLE
                     TFVDRSSLPASLPADIAETAKADLLLKIEKKFADPFSYSAARLAEETFGSPMYGTAMFG
                     RKEKVQAIQPKRFLDASDFKTDLLSQQKQLYVIGNVQELHAGGYSRHAPSMNVRKPVNK
                     NIYETETRSAAGPSVMTLGFDCGEMNGFRDYIKIQLIDGLLGKYGHSALFRHFREKQMA
                     VYHVITRYDIMNNLLLVSVCTDRVQEKEIPPRVIETVMNFHVDDQELEKAKQFLKNEIL
                     LQLDSPEGLLAYMGILRHYLYKKEDILDGISTITCRDLLQYVTNIEYIGAHVVRG"
     gene            14962..16239
                     /locus_tag="C6W22_RS11520"
                     /old_locus_tag="C6W22_11510"
     CDS             14962..16239
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015483836.1"
                     /locus_tag="C6W22_RS11520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11510"
                     /product="pitrilysin family protein"
                     /protein_id="WP_106047190.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 1e-12, bitscore:
                     43.7, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKETFFHQLDARTEITYADNGLKICRVKFPNAHMRLCNVKVDFG
                     SRDIRLHSGDSEKVLPYGTAHFLEHVLFWHNGRNLYSDFFDHGALLNAFTTYTDTNFMF
                     TSLPDRLEHTIPKLLDALWNHSFDENIVAQEKSVIKSEIEAAHLNQQLHYHYQMLNLLS
                     PASPAAIFPAGRTEDIEALTINDLKEAYATGYQPQRMTMFLIGGSEDTETILPSHLRLR
                     GRSGHTAKRKFMPACPPLLQNQSLGDAECSGETWTGLHIGALPDKNDLFTLQMYWDIVS
                     RILFHIDSPLFQEIRQTRLLNIQSLSAESHVSEDGGFLILHSKGAHSSAYIDVATYYVM
                     QQKCQAEAWLEYGKESLLNAIIYDSDYVRKCFEWAAECERYDCSFFELYRLIQNMTVQD
                     FLYLIDTVASAKKATIHVSHPEVVGQ"
     gene            16236..16937
                     /locus_tag="C6W22_RS11525"
                     /old_locus_tag="C6W22_11515"
     CDS             16236..16937
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015250988.1"
                     /locus_tag="C6W22_RS11525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11515"
                     /product="hypothetical protein"
                     /protein_id="WP_063638165.1"
                     /transl_table=11
                     /translation="MKKSTVFTVLLLLMVMAAHSFGWFQASAEAAGQYVQLIKNDYVRL
                     GLLSCAASVLMLPAFLYLHYVTRSVKSMTAAFQKITQSHQSCCDFQHRKLCSRYAGDVK
                     SLRESYKGIHQTYVMGAVLCQVIVFGYMFEVVKSIPFSFNAPPAVTKGLAIVLTIYLLF
                     YMRSYLLQLLQNGQTAKKAVVLLLAGAGIWWMLSFTMSELLFLILLAAIQQTGSLVYKR
                     ITYRSPASLDL"
     gene            complement(16944..18320)
                     /locus_tag="C6W22_RS11530"
                     /old_locus_tag="C6W22_11520"
     CDS             complement(16944..18320)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012118684.1"
                     /locus_tag="C6W22_RS11530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11520"
                     /product="YncE family protein"
                     /protein_id="WP_106047191.1"
                     /transl_table=11
                     /translation="MKKNDLSAFQENCFCFCDEEISREALFQVPIDIPEGFTIDSAEAA
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVQYAVRLQGTVTLLVSVSPVRNQYGQGDGA
                     VSVIHNAEIDQVVYYSDNPDDCPDFSDITIENLVVVPPFYGSPLSVTGTIVLVPAPDQR
                     SYVFTANTGDSTVSVIDTDVNTLVSTISLSDIPTDLGVTLDKAYTYVLHRNANLVSIIN
                     NETLTVTQTIPLAGAPRKIQFETGGGFAYILAGGSSIYEINISSQTITNTFTVSPAADD
                     FALDPNGQFFYTTNSVFWVVNKYDINTGQLIDSLSNFETPNLIETPLIGDFAYLENGEL
                     RPNVVSVIDLTTFSESSQINRLFDGLITIVFSADGTRAFFLEPYYDSFPENLTVVDTTL
                     HTFITTASLPGAIDLTVTPDNQYIYVAQPAANTVTVYRTSDYTAVTVIPVGGGPSAISM
                     "
     gene            complement(18360..19721)
                     /locus_tag="C6W22_RS11535"
                     /old_locus_tag="C6W22_11525"
     CDS             complement(18360..19721)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326493.1"
                     /locus_tag="C6W22_RS11535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11525"
                     /product="YncE family protein"
                     /protein_id="WP_106047192.1"
                     /transl_table=11
                     /translation="MKKIERSFKEKAVRQQEDCLCFCEEEASREAMFQAPIEVPEGFVV
                     DPAEAVANVTWNADSLSCVSERCFIQTGPGPDEIEIHFAVRLQGTVTLLVSVSPVRNQY
                     GQGEGAVSVIHNVEIDQVVYYSDEPDDCPDLSDITIENLVVVPPFYGSPLSVTGTIVLA
                     PEPEPEPVYAFTANPDDQSVSVIDTNTHTVITTISLPYEPTGIEITPDKASTFVLHLNN
                     SVISVIDNGTLTVTASIPLDQPPETIKFMPEHDFAYVLAGNAIYVIRIETSAVERSIPV
                     EGYDIAIDPNGLFAYVLDFGLVQKVDLSTGEVTGTIERELIVNSIETKPPERYAYVLEQ
                     DQFLNFLTIIDLDTFTISSTQELEYEGEYRMFKSGSGLYLFDDFTHNLYSVSPSGAGVI
                     GNLPQSASDFAFTPNGEFLYATHFIEQSITVYNTDDYSVETVISLGVSPSDIAI"
     misc_feature    19818..19827
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            20004..20558
                     /locus_tag="C6W22_RS11540"
                     /old_locus_tag="C6W22_11530"
     CDS             20004..20558
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326492.1"
                     /locus_tag="C6W22_RS11540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C6W22_11530"
                     /product="YdhK family protein"
                     /protein_id="WP_106047193.1"
                     /transl_table=11
                     /translation="MKRNTTLIGIVSLLLLLMLSACGSDNQDKKSDQTMNMDDTHTHSE
                     SSEIPEGLTAAQHPTYKVGSQAIIKADHMKGMKGAEATITGAYDTTAYAVSYTPTTGGT
                     RVENHKWVIQEEIKNASDETLKPGTDVIIEADHMKGMKGVTGKIDSAEKTTVYTVDYTP
                     TTGGEKVKNHKWVTESELSSK"
     misc_feature    20722..20738
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     misc_feature    complement(21197..21210)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.06"
                     /tool="antismash"
     misc_feature    21236..21249
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.37"
                     /tool="antismash"
     misc_feature    21453..21465
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: medium, score: 23.09"
                     /tool="antismash"
     misc_feature    21563..21572
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    21578..21591
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.7"
                     /tool="antismash"
ORIGIN
        1 acggttggtt ttcggtcctg atttcagctc aagctttcct ttttttaatg tccagccgcc
       61 tttatatttg tcttggtcct cccactgctt cggatagccg atgccaggtt ttgtttcaac
      121 attattgaag tacatatatt ccgctccgga acggtttgtc cacgtgtttt tgcaggtcac
      181 gctgcatgtg tggcagccga tgcatttatc taaattcatg accattccga tttgcgcttt
      241 aatcttcaag ccaatcgacc tccttcagct tgcggatgac cacattcaga tcacgctgat
      301 tcccagttgg gccgtagtaa ttaaatccgt agctaagctg agcatagccg ccgatcattt
      361 gtgtcggttt aacatgaatc cttgtcggac tgttatgggt gccgccgcgg ttattcgtca
      421 gttttgtgcc gggtacgttg atgtggcggt cttgtgcatg gtgcataaac gccatccctt
      481 taggaatacg gtgagaaaga acggctctcg ctacgacaac gccatttcgg ttgaagcatt
      541 caatccaatc gttgtctcgg atatctgtgt cctctgcatc atctttattc atccacactg
      601 tcggccctcc gcggaatagc gtcagcatcg gtaatgaatc aaagtacatg ctgtggacgg
      661 accatttgtt atgcggcgtt aaataattga gaacgatttc tttgccctct tgatcaggcc
      721 gtttactcag aaacggacga tgctggagga tcggtttaaa tgtcgccatc gtttccccga
      781 actccatcat cagctcatga tcgacatagt aagactgtct gcccgtcagc gtccgccaag
      841 ggattaattt ttccacattt gtcgtaaacg gcgagtacct gcgtccccct ttttctgagc
      901 ctgtaaatgc cggagacgtg atgaccgttt ttggctgagc ggtgatttgt tcgaacgtaa
      961 agcattcttc ttcccgctct tcagccaggt cttttaactt caggtttgtg atgtcttcaa
     1021 gtgattccca tgctttcacc gcaacttttc cattcgaagt ggaagaaagg gttaaaatgg
     1081 cttctgccgc ctgcttggcc tcacttatat tcggacatcc cttggcgacg ctgtccgttg
     1141 tgatttctcc cagtctcttt ttgagtgatt catattcatc ggctatcgac cagctcatcc
     1201 cttttgttcc gctcggtttt agggcggtgt tagggccgag tgcggtcatt ttatgaaaga
     1261 tttgtttata gtcccgttca acaacatgaa tgttcggcat cgttttcccc ggaacggctt
     1321 cgcattcgcc tttgctccag tcattgattt ttccgaaagg ctgcgccatt tcctgcatag
     1381 tgtcatggag gagcggcgtc gcgacagctt ctttaaccgg ctccatctct acttcttcag
     1441 ccaagtcgga tatggctttt gataatgctt taaaaatatc ccagtctgac ttggattccc
     1501 aaggcgctga gatggccgga gcaaaaggat gaataaacgg atgcatatcc gtactgctga
     1561 gatcatgttt ttcataccaa gtcgccgccg gaagcacgat atcggaatac aatgccgttc
     1621 cagccattcg aaaatcgaga ttaattaata agtcgagctt tccttccggt gcttgatcat
     1681 gccatttgat ttcttccgga cggatgctct cgctgtcgtc attcatcaat ccgtttgtcg
     1741 tccccaagag atgcttaaga aaatattcat gcccttttcc cgaacttgag atcagattcg
     1801 ctctccatac aaaaagattt ctcgggaaat tggcttcatc gtcaggatct tcaatggcaa
     1861 atttcagttt tttttcttgg agctggcggg ccacatagtc agcaacgtct tttgttgtcc
     1921 ttgcccccgc tgtttcagct tccttgtaaa gatcaattcc gtttttatta aacgtcgggt
     1981 aagacgggag ccaccctaat cttgccgcca gcacgttgta gtcggcgtga tgcttgtagc
     2041 gggaggatgc tgcgatcgga gaagccaagt cactgatcgg ctgatcctcg tagcgccact
     2101 ggtctgtcgc aaagtagaag aatgatgtgc cgttttgcag ctttggcgcc ccctcccagt
     2161 cctttgcatt agcaatcgtc tgccagcctt cagccgggcg aagcttttcc tgccccacat
     2221 agtgagccca tccgcccccg tttacacctt gggcgccgac taataaaaca agatttaaaa
     2281 ccgcccggta aatcgtgtca gagttgaacc aatggttaat tcccgcccct aggataatca
     2341 ttgaccgtcc gtctgtatcg atcgcatttt gggcaaattc tctggcaatt ttaacgacca
     2401 tctccctttt gatccctgtc acctgttctt gccaggcggg tgtaaacggc tcagcatcat
     2461 caaacgaggc ggctgatttc tgcccgattc cccgattgac gccatagttt gccagaatta
     2521 aatcaaaaac ggttgtgaca tatacgtctt cattattcag gtttagtttc ttaatgggaa
     2581 gatcacgctc aagcactctg tttccctcat ttgagaaata agggattcga actgtgccga
     2641 tttcgtcttc tattccgagc actgacagcc tcggttcaat ttgttcccct gtatcttcat
     2701 ctgccatgtg cagattccat ttcttttggc cgtcccatcg tgatcccatt gttccttgcg
     2761 gtatcgcaaa tgcgtttgta cgttcattcc acacagcagg cttccactga tcatgctctg
     2821 tttgccgtcc gatatccttc gcatggagaa aacgtccggc tgtataagcg ccatcttctt
     2881 ttgacaaggt gacaaaaaac gggaaatctg tgtattgctt cgcataatcg atgaagcgct
     2941 ctgtttcttg attcacgtaa aattcttgca ggatgacatg ccccattgcc attgcaagcg
     3001 cgccgtctgt tccctgacgg atgctcagcc agtcatccgc aaattttgac gattccgcaa
     3061 aatccggact aattgagatg acttttgccc ctttatagcg ggcttctgcc aaaaagtgcg
     3121 catccggcgt tcttgttaac ggtacattgg atccccatgt gatgatatag cccgaattgt
     3181 accagtcact gctttccggc acgtctgtct ggtctcccca gatttgcgga gacgctgggg
     3241 gaagatccgc ataccaatca taaaagctca gcatagggcc gccgattaat gacataaacc
     3301 gcgagcctga cgcgtggctg atcattgaca tggcgggaat cggagaaaat ccgacgttgc
     3361 ggtcagggcc gtatttcatg actgtatata atagagaagc agaaatcagt ttcagcacct
     3421 ccggccactc agcgcgcaca aaaccgcctt ttcctctcgc ctgtttatag gacttcgctt
     3481 tttccggatg ctcaacgata gatttccatg cttccaatgg atttttgtgt gtttgcaatg
     3541 cttcccgcca catagtaatc agcacaccgc gaacgtatgg atatttgaca cgcagcgggc
     3601 tgtagatata ccaggaaaaa cttgccccgc ggggacagcc ccttggctcg aagtcaggca
     3661 tatcagggcc agttgaagga taattcaaat tttgcccttc ccacgtgacg atgccgtttt
     3721 tcacataaat attccagctg caagatcccg tgcagttgac tccgtgggtg gagcggacaa
     3781 ctttatcgta ctgccatctg tttctatata cattctccca atcgcgatct tcgtatgttg
     3841 tttgactatg tttattagaa tgatgctcaa taggagagaa atagtttagt ctcctgaaca
     3901 gcggactcat tttcttcttt ttcatcgttg cttcactcct ttgagtcagg tgattctcat
     3961 ttcactatat acagaggcag catcgttcct tgtgaacttt gtcacataca ccccttattt
     4021 cacaaatgtt tcacattcag gattcaaaaa aacccggttc ctggttagga atcgggagtg
     4081 acgttttcat cctgagatgt gtgcagataa cgcaaaaata actggtagga aaaaaagaga
     4141 ttttcctgaa gcatgaccag aaaattcgtc tgcagctgcg gatgataggt cattattttt
     4201 ttaaatttgc aaaaaggaat ttccaacacg agtgtgtcat gagatgttgt gactgaaatg
     4261 aaaggagata aaagcagctc gccattttga tcaatgggga acacatcacc ttttttccaa
     4321 aatgcaatgg cgcgcgatcc ttcaggcagt ctgctgtcaa taaaatgaat gctgcctttt
     4381 aatacaatat aaactgattg tgaatgcaaa aaagatggag actgatcaga tgagcaacgg
     4441 atgaacttcc cgttattcag caatgtttcg acaatgggaa gagatacttg attaaacatt
     4501 ggaagatgtt tcagaaataa taaatagtca cactgattca taggaaagcc tcctaagaga
     4561 taaggatagc tttagtgtat cttgattgaa tcaatacagc agtgatgtaa ttcacagaaa
     4621 ttatgataaa tgtcacttat cggaagaatg attgctttta taatgaaaca gaaaggagtg
     4681 tttcaatgaa ggtgctcatt ccgaagcagc acggtgcatg ggctatgctg ttgattccgt
     4741 tttgcctcgg tatggtgaag ggaggtcccg ttctatggca tatcccgcta tttacgggct
     4801 ggctatttct ctatttaacc gtttacccca ttaccttggc agtgaaaaag aaaaaaacaa
     4861 aagactatca aaaatggatt ttttattacg gcattgcagc ttgctgctct atcattgccg
     4921 ttgtcatcca taagccttcg ttcatctggc tcggcttttc tttgtttccg ttgttcctcg
     4981 ttcatgtcta ttatgcccgc agaaaaaacg aaagagcgct tctgaatgat attgcgggag
     5041 tcttgttctt tagtacaggc ggacttgcca gctgctggct gggggcggga agccttgacg
     5101 gctgggcatg gtttattttc gcgcaatcca gcttattttt tatcggaagt tccttttacg
     5161 tgaagtctat gatccgggag aaaaacaaca aaacatttgc atactgttca tggggatatc
     5221 acctgcttct tccctttctt tctatatctc tcggagcaag ctgggggggc tctcgctttt
     5281 attccaagca gtttgagagc atggttctta cacggaaagg agcgatctat taagacgatc
     5341 ggcattcttg aaatcgtgaa cgcgtgcttc tttttcgcag tcatgtgtat ttttttaaca
     5401 agataaaaca aggactgaag tttgcagtcc ttgtttattt cttgattaat cgatattgca
     5461 aatatccagc gggcaatttt cgcactcaat ttcacatctt aaatagtccc gctgatgcaa
     5521 aacaatcttt ccggattcct caattgaaat gattccttgt ttacgaagat cacccagcat
     5581 gcgattgaca ctctctcttg cagccgcaca aaacttcgcc aaatcatggt tcgtcagtgc
     5641 aatgtttata agaattccgt cgcttcgttt caccccatag ctatttgaca aacgaatgag
     5701 tgtggaataa agcgcccctt ttttgccatg aagaagaagg tcacggattt tggactggat
     5761 ttttcgcagg tgggtgctca tccatttcat aaattcaaat gtcaaagcac cgttttgaac
     5821 caattccttt tccagtttgt ttttattgat gacaaacact tcaccgtctg ctaacacttt
     5881 tgcactcagc atatatctcg gttcttctgt aaaaagtgtt aattccccga caatatcatt
     5941 tttttggcag atcctaagcg tcagatcctt gccgtcagac gtcagtttgc caatttcaat
     6001 gagtcctgat tgaatcagat aaagctcttt tgcatccatt ccttcttgaa acagaaacgt
     6061 gtttttttca atttttcttt ttgtactgat tgattccagc aattgatgca gatcttgtga
     6121 gagaagatcc ttatcagatt ttcgaacaga gagaaaattc atgagctcac ctcgaagata
     6181 gtcacgttgt gtatttctat tgtaacgtga atcgatttgc atcattttaa aaaaacttac
     6241 aatctcgtga attccccaaa cgccggcttc ccattagttt acgctgtgcc catttctctc
     6301 agtgtgcgtt ttcatccttt cctgccaata catccaaatg acaatgacaa agctggctaa
     6361 agcagcttcc gagagcgcca taaatccgat tgcatattgt cctgtcgctt gaaatacgct
     6421 tgccaggatc agcggcggaa agaatcctcc caatcccccc atggcagaaa caataccgtt
     6481 tgcaattccc gcttgttttg agaaataaaa aggcaccaat ttaaaaactg ttccgtttcc
     6541 aattcctgag cagacagcaa ctgttaacgc cccaaaagcg taaatgccga gactcggtga
     6601 gaacgacaag ataatgcccg ataatgtcag acccgcgaag acgtacatta acattctaag
     6661 cggactcacc ttatctgcca aaaatccgcc aacaggtctg agaagcgtgg acacagcaat
     6721 aaaacctgcc gttctaaacc cggcatccac aggactaaga ccaaagtgct gaacaagaaa
     6781 gttaggaaga taaatggtaa aggcaacgaa cgcgccaaat gttataaaat aaaaaaggct
     6841 taagaaccac aacagatgat ttcggtaaac ggcttttatt tgaaccttta cggaaacttt
     6901 gactttcttc tcgtttcgat cgcccaggaa aaagtgcagc aaagcaaata aagccagcag
     6961 gaccatatac atttgcaccg tactcttcca tcccacagat tgagcaacaa caggagctgc
     7021 aaacgttgtg atggcggttc cgatatttcc agctccgtaa atgccgttta taaaaccgtg
     7081 tttttcctta ggataatact tcggaagaga tgtcacccca atggagaaaa ccgctcctcc
     7141 aatccccaag aaaaaaccgc ccacggctaa atcaaacaca gaatctgcga tactgatcca
     7201 aaatacagga aacaaaagca atagaaagct gatcataaaa gtcatccgcg cgccaaacct
     7261 gttcgtgtaa tatcccaaag gaatgcggag aagtgacccc agaatgacag gtatggccgt
     7321 aaccagcgaa atgtcgccgg cgctcaaatt aatatcagat gacatttgag aaattaatga
     7381 agaaatcaaa acccaaacca taaatcctgc caccaagctg catgactgta acgataattg
     7441 aatgttttga cggttaatca ttcggcttgc ccctttcaat gattcaataa tcagtcttat
     7501 catacaaaaa ctcggtgaat aggattgtga agttcatcac acgtttttta acaaaaaagg
     7561 acaaagcccg gggctttgtc ctttcatctt cattacattt tttcaggagc cgaaacgcca
     7621 atcaactgaa gcgcattatt cagcgtgatt tgcgttgctt tcattaaagc taagcgtgcg
     7681 cggcttttct cttcattttc aggatcgatt accttttccg cattatagaa gctgtgcaga
     7741 gaagctgcca agtcataaat atagttcgtc acgcggtgcg gaatgcgttt ttccgccgct
     7801 tccgccactg cttcagggaa gccgccgatc gttttcagca aatcgtattc tttttcagaa
     7861 ttgacggcgc taaagtcaag atcagacgca ggcgttaatc cctgctcttc tccttggcga
     7921 agcatgctgc aaattctcgc gtgagcgtat tgcgcgtaat acaccggatt gtcatttgaa
     7981 gtggacaccg caagatccaa gtcaaaatcc atatgtgtat cggcactgcg catcgcgaag
     8041 aaataacgga cggcgtctaa gccgacttct tcaatcaagt cgcgcattgt taccgctttt
     8101 cctgtacgct tgctcatttt cattttctcg ccgtttttat atagatggac gagctgaatg
     8161 atttctactt ctaacgttcc tttttgatag ccaagcgcct caatggccgc tttcatccgc
     8221 ggaatatagc cgtggtgatc tgcgccccag acgttgatca gcttatcgaa tccgcggtct
     8281 agcttgtcct tatggtaagc gatatcaggc agcaaataag tgtaagtgcc gtctttttta
     8341 atcaaaacac ggtctttgtc atcgccgaat gttgttgagc ggaaccaagt tgcgccgtct
     8401 tcttcataca cgtggccttg tttgcgcagc gcttcgagcg ccttgtcgat ttttccgttt
     8461 tcgtataatg acgtttcaga ataccagaca ttaaatggca cgcggaagtt ttctaagtct
     8521 acacgaagct tttccaactc atacttcaag ccgtattcgc ggaagaactt ctgtctttcg
     8581 ctctcttctt ctttgacaaa gcggtcgccg tattcttcag cgagacgctt cccgattgcg
     8641 ataatatcct cgccgcggta tccgtcctca ggcatttctt tttcaaggcc gagcgcttca
     8701 aagtaacgga cttcgacaga aagcgccaag ttgttgatct gatttcccgc gtcattgata
     8761 taatattcgc ggctcacatc atatccggct ttagccagca cattgcacag agaatcgccg
     8821 acggctgctc cgcgcgcatg gcctaaatga agatcgcccg tcggattcgc agatacgaat
     8881 tccacttgga tgcgctcgcc gtttccgata tttgtttccc cgtatgcttc ccccgcttcc
     8941 aatacagatg ggatcagctt cgttaaatat tgattatcca tatagaaatt gataaatcca
     9001 gggcctgcga tatcaagctt ttcaattgaa gcctttcctt tatcaaaaga agctacaata
     9061 tcctcagcga tttggcgcgg ggcttttttt gcgattcttg ccagctgcat cgccatgttg
     9121 gttgaataat caccatgtgt tttatctttc ggtgtctcta aaatgacatt tggaatctgg
     9181 ctttcatcag ccaatcccgc tttcagaacg gctgctttaa tttcctcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtcaa gtcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctg ctgttcgtct cccacatgca tatcataagc tatgctgata cggcctcttt
     9361 ctttgccgat gtcagactga atcgattttg tgcttgtagt cagctcaagc tcgccaaatg
     9421 acattttata tttggcaatg gtagagactc ccggcacaaa ccgctgattc attttcactg
     9481 cgcctgacct catgacaaac acttcgctct cgcttacttt cacaatcgtt ttcactttgc
     9541 ccaaatcgtg ttcttcataa taagaaagat acactttatt ttgtttcaca tgataagatc
     9601 cggaggtgcg gaactcaatg acctcttctt tcccgtcatc cgcaatcaca gattttacat
     9661 ggagcgttat cggtgtctct tgtttcatgc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc gctatttaaa gttcaactgc ttctatctta ccatcattac
     9781 tcatcagttt tgaagataaa cctcataaaa agcggttaat gaaacgaaga gcatttaaat
     9841 agaaattaat gccgttttga atgttacatt tttctgaaat ctatctaata tttttcacat
     9901 tttcttcaaa atatacatat tgaaaaggta ttttgatagt tttaagatta aattacatca
     9961 gagatatgct agaaaaatta aacaagggag gatttctatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgttcaat cggagctgct tgtttagtgg acggacctat
    10081 tccagacttt gaaatcgcag gtgcaacagg gctattcggt ttatggggat aaagcatttc
    10141 ctaaaagagg catagtaaat tactgtgcct ctttttgaaa agtattttta ctttctatct
    10201 actccttagt tatacataca tgttttctca ttatttgtat catatgtata ggagatggta
    10261 tttttgctta tagagcagat gtttccattt atcagtgaaa gtgtaagagt tcaccagctt
    10321 cctgagggcg gagtattaga aattgattat atgcgtgata atgtctcgat ctctgatttt
    10381 gaatacttgg atctcaataa aacggcttac gagctttgta tgctgatgga cgggcaaaaa
    10441 acggcagaac aaatattaga atgccaatgc gcgacgtaca atgaatctcc cgaagaccac
    10501 aaggattggt attatgaaat gctcgacatg ctgctgaaca agcaggtcat tcgtcttaca
    10561 gaccagccag aatatcggcg cattgccaca agcgggagca gcgactttcc gatgccgctg
    10621 catgcgacct ttgagctgac tcaccgctgt aatttaaaat gcgcccactg ttatttagaa
    10681 agctcgcctg aagcgctggg aacggtatct cttgaacaat tcaagaaaac agcggatatg
    10741 ctgtacgaaa aaggcgtttt aacatgtgaa ataacgggcg gagagatttt tgtccacccg
    10801 aacgccaatg aactccttga atatgtatta aagaaattta aaaaggttgc cgtcttaaca
    10861 aacgggacgc tgatgcgaaa agaaagcctg gagattttaa gagcatataa gcaaaagatc
    10921 atcgtcggta tttcactgga cagtgtccat tctgaagtcc acgattcctt tagagggaga
    10981 aaaggctctt ttgcccaaac ctgtaaaacg ataaaattat tgagtgatca cggtattttt
    11041 gtcagagtcg ccatgtcggt tttcgagaaa aacatgtggg aaattcatga catggcccaa
    11101 aaggtgcgcg atcttggtgc aaaagcgttc tcttacaact gggttgatga tttcggaagg
    11161 ggcagagata ttgtccatcc gacgaaagat gccgaacagc accgcaaatt tatggagtac
    11221 gagcaaaatg tcattgatga atttaaggat ctgattccga ttatccctta tgagagaaaa
    11281 cgtgcggcga attgcggcgc aggctggaag tcaatcgtga tcagcccgtt cggagaagta
    11341 cgcccgtgcg cgctcttccc gaaggaattt tcattgggaa atatctttca tgattcatat
    11401 gaaagcatct ttgattccgc tctcgtccat aaactatgga aagcgcaggc gccgcggttc
    11461 agcgagcatt gcaagaaaga caaatgccca ttcagcggct attgcggagg ctgttactta
    11521 aaaggcttaa actctaacaa atatcaccgt aaaaatatct gttcctgggc gaaaaatgaa
    11581 caattagaag atgtggtcca gcttatttag gagggaaatg ttttgtcacc aacacaaaga
    11641 aaatggctat tgtatatcct ttcattcgtg tttgtcatcg gcgcggttgt ctatttcgtc
    11701 aaaagcgatt atttgtttac tctgatctcc attgtgattg ccattatatt cggaatgaga
    11761 gcgcggaagg ctgaatctcg atgagcatgt tggatataca cgctttatct gtttggtacg
    11821 aacaagataa cgtcatctta gaaaacgttg atttacattt agaaaaaggc gccgtttacg
    11881 gactgcttgg agtaaatggc gccggcaaaa caacgctgat caatacgctg acaggcgtta
    11941 atcggaattt tagcggaagc ttcaagctgt gcggcattga agttaacgcc aaaacgccgc
    12001 tgaagacatc agatcagctg aaaaccaacc gctacttcgc ggcggattat ccattgcttt
    12061 ttacagagat cacggcgaag gaatacgttt ctttcgtcca ttctctttat caaaaagaat
    12121 ttcacgaaca acaatatgtc agtttagcag agaagtttca cttttctcag tacacgaatc
    12181 ggagaatctc agagctgtct ctcggcaaca ggcaaaaggt tgttctgatg acagggttat
    12241 tgctgcgggc tcccctgttt attttagatg agccgcttgt cggcttggac gtggaatcga
    12301 ttgaagtctt ttatgagaaa atgcaggagt attgcaaggc aggtggaacc attttgtttt
    12361 cttcccatct gcttgatgtg gtgaaaaggt tttgccatta tgcagctatt cttcatgata
    12421 aacagattcg caaattgatt cctattaagg atgacacaga tctgcgccgg gaattttttg
    12481 aggtgatcgg ccatgaataa tgtgtttcaa attctttccc tgctgttcaa acagctttac
    12541 ggccggcaag ggaaaaagga tgccattcgc atcaccgccg gacttgctgt tctggctttg
    12601 tttgaaatcg gactgatccg gcaggccggc attgatgagt cggttttagg aaaaacatat
    12661 gtcacactcg cgcttctttt tatgaatgtg tatatggtat ttatttccgt ttcttcacaa
    12721 tggaaggaat cctacatgaa gctgagctgt cttttgccaa tctcttcacg tagcttctgg
    12781 cttgctcaaa gcgtggtttt gtttgtggat acttgtttga gaagaacgtt attcttcttt
    12841 attttaccgt tgtttttatt tggaaccggc acgctttcag ggacggaaac gttattttgg
    12901 atcggcaaat tttcgttttt cacagtctac tccattttat taggcgttct attaagcaac
    12961 ctttttgtca aaaagaaggg atttgtgttc ctgctgcatg cggcggcatt tgcctgtatc
    13021 tgcgccagcg tggtttttat gcccgctgtg acgatcccat tatgcggggt tcacatggca
    13081 tggggcgttt tctttgattt cccctccttt ctgcaggtgc ctcatcagca gaacaagatg
    13141 cattcattca tgcggacatc ggaattttcc ttttataaga gagaatggaa tcggtttatt
    13201 tcgtcaaagg cgatgttatt aaactacatt gtcatggcgg ctttcagcgg ttttttttcg
    13261 tttcagatga tgaaaaccgg catcgctgat cagcatatca tttacattgt gattaccgcc
    13321 ttgctattaa tttgttctcc tatcgcttta ttgtattctc ttgaaaaaaa cgaccggatg
    13381 ctgttaatca cgcttccgat taaacggaga acgatgtttt gggcaaaata tcgcttttat
    13441 tccggtttgt tggcaggcgg gtttattttg atcgttatga tcgtcggttt gatcagcagc
    13501 cagccgattt cagtcatgac ttttttgcag tgtatcgaat tgctgctgat gggagccttt
    13561 attcggttaa catctgatga aaaaagaccc tctttcgggt ggcagacgga acagcagctc
    13621 tggagcggct tctcaaaata ccgctcctac gtattttgta ttcccctatt cttagcaact
    13681 atcgctggca ctgttatctc cttggcgatc atcccgattg ccgggctgat cattgtctat
    13741 ttgctgcaaa aacaggaagg tggtttcttt gatacaagga gaaaaagtga acgatttgga
    13801 aatgaacctg ttaacgactg atcaattttc aacaatctcc atcgccgcga gctttctgaa
    13861 accgatcgaa aacgcggcag agcctgaaga agaaacaatc tatttttacg gtgcggcagc
    13921 ctatctaaaa caaaacatca ctgacatctt tggatatgct gccggcagcc gctttatcta
    13981 ctcagcgaat ctattttttg accggcagct caagacatac ggaacccgct tgattcatcc
    14041 gctatatcac aaaaatctca acattgatga tgtgctggaa acatttgttg atagatcctc
    14101 tcttccggca tctcttccgg ccgatatcgc agaaacggct aaggctgacc ttttactgaa
    14161 gatcgaaaag aagttcgcgg atcctttctc ttactcggca gcccgtctgg cagaggaaac
    14221 gttcggcagt ccgatgtacg gcacagctat gtttggccgg aaagaaaagg tacaagcgat
    14281 acagcctaaa cgctttctgg atgcatcaga ttttaaaact gatttgttgt cccagcaaaa
    14341 acagctttat gtgataggaa acgttcaaga gttacatgcc ggaggatatt ccaggcacgc
    14401 accttccatg aacgttagaa aacccgtcaa taaaaacatt tatgaaacag agacacgcag
    14461 cgccgcaggc ccttccgtga tgacccttgg gtttgattgc ggagaaatga acggtttccg
    14521 tgattatata aaaatccagc tgatagacgg attactcgga aagtacggcc attccgcatt
    14581 atttcggcat tttcgcgaga aacaaatggc ggtttaccat gtcattaccc gctatgacat
    14641 catgaacaat ctgctgcttg tatccgtatg taccgatcgc gttcaagaga aggagattcc
    14701 gccaagagtg atcgaaacgg tcatgaattt tcatgtagat gatcaggaat tagaaaaagc
    14761 gaagcaattc ctgaaaaatg aaatccttct gcaattagat tctccggaag gactcttagc
    14821 ctatatggga attctgcgtc attacttata caaaaaagaa gacattctag acggtatttc
    14881 aacgattacc tgccgcgatt tattacaata cgtgaccaat attgaatata ttggagcaca
    14941 tgtagtaagg ggatgaggag attggagaaa gaaacctttt ttcatcagct tgatgcacgt
    15001 accgagatca cgtacgcaga caatggacta aaaatatgca gagtaaaatt ccccaacgcc
    15061 catatgaggc tgtgtaatgt caaagtcgat ttcggcagcc gggacatccg tttgcactcc
    15121 ggagacagcg aaaaagtgct gccgtacggc actgcgcact ttttggagca tgttctcttc
    15181 tggcataacg ggcgaaatct atacagcgat ttttttgatc atggagcgct tttgaatgcg
    15241 ttcaccacat atacagatac aaatttcatg tttacctctc ttcctgatcg gctggagcac
    15301 acgatcccga aactgcttga tgctttatgg aatcactcct ttgacgagaa tattgtcgct
    15361 caagaaaaaa gcgtgattaa aagcgaaatt gaagcagctc atctcaatca gcagcttcat
    15421 tatcattatc agatgctgaa tttgctttct cccgcatctc ccgctgcgat ttttcccgcg
    15481 ggcagaacgg aggatatcga ggctttaacg atcaatgatc taaaagaagc ctatgcaaca
    15541 ggctaccagc cccagcgtat gacgatgttt ctgatcggcg gctctgaaga tacagaaacc
    15601 attttgcctt ctcatctccg gctgcgcggc cgctccggcc ataccgccaa gagaaaattc
    15661 atgcctgcat gccctcccct cttacaaaat cagagcctgg gtgatgcgga gtgttcgggg
    15721 gaaacatgga ccggattaca tataggcgca ctccccgata aaaacgatct ttttacattg
    15781 caaatgtatt gggacatcgt ctcccgcatt ctttttcata tagattcgcc gttgtttcaa
    15841 gaaatccggc aaacgcgcct ccttaatatc caaagcttat cagcggaaag tcacgtgtca
    15901 gaagatggcg gctttttgat ccttcacagt aaaggggcac attcttcagc ctatatcgat
    15961 gtagcgacat actatgtgat gcagcagaag tgtcaggcgg aagcttggct ggagtacggc
    16021 aaggaatctt tgctgaacgc gatcatctac gacagtgatt atgtgcgtaa atgctttgaa
    16081 tgggcggctg aatgtgagcg gtatgattgc tcttttttcg agctttaccg gctgattcaa
    16141 aacatgactg tacaggattt tttatatctt attgatacag tggcttctgc taaaaaagca
    16201 accattcatg tctctcatcc agaggtggtt ggacaatgaa aaaaagcact gtcttcactg
    16261 tgttattgct gcttatggtc atggcggccc attcatttgg ctggtttcaa gccagcgctg
    16321 aagccgcggg gcaatatgta cagctgatca aaaatgatta tgtgcggctc ggcttgcttt
    16381 cttgtgccgc ttctgtgctg atgctgccgg catttttgta tcttcactat gtcacccgat
    16441 ccgtcaaaag catgacagca gcttttcaga agataacgca atctcatcaa agctgctgtg
    16501 attttcagca tcgcaagctg tgcagccgtt atgccggcga tgtgaaatca ttgcgcgaaa
    16561 gctacaaggg catccaccaa acgtacgtga tgggggctgt attatgccaa gtgatcgtgt
    16621 tcggttacat gtttgaagtg gtcaagtcca ttccattcag cttcaacgcg ccccccgctg
    16681 tcacgaaggg gcttgcgatt gttctcacca tctatttatt gttttatatg aggtcatacc
    16741 tgctccagct tctccagaat ggacaaacgg ctaaaaaggc tgtcgttctg ttattagcag
    16801 gagccgggat atggtggatg ctcagcttta ccatgagcga actgctcttt ctgatcctct
    16861 tggctgccat ccagcagacc ggatcacttg tttataaacg aatcacttat cgcagtcctg
    16921 cttctctcga cctgtaaaag catctacatc gaaatcgcag acggaccacc gccaaccgga
    16981 atgaccgtca cggctgtata atcactcgtg cgatataccg tcactgtatt ggctgcaggc
    17041 tgcgcaacat agatatattg attgtccggt gttactgtga ggtcaatggc accggggaga
    17101 gaggcagttg ttataaaggt atgcagcgtt gtatcaacga cagtcaaatt ctccggaaat
    17161 gaatcataat atggctcaag gaaaaatgca cgagtcccgt cagcagaaaa aacaattgtt
    17221 attaaaccgt caaacagtct gttaatttgt gaagattcgc taaatgttgt caaatctatc
    17281 acagaaacga cattcggcct tagctcacca ttttccagat aagcaaaatc ccctattaac
    17341 ggggtttcaa taagatttgg tgtttcaaag ttacttaaac tatcaatcag ctgccctgta
    17401 tttatgtcat atttattaac gacccaaaat acagagttgg tcgtatagaa aaactgtccg
    17461 ttagggtcta gggcaaaatc gtccgcagcg ggtgacaccg tgaatgtatt ggtaatggtt
    17521 tgcgaggaaa tattaatttc ataaatggag ctgccccctg cgagaatata agcaaatcct
    17581 cccccagttt caaactggat ttttcttggg gctcctgcaa gagggatggt ttgtgtaacc
    17641 gttaatgttt cgttgttaat gatcgataca agattcgcat tcctatggag aacatacgta
    17701 tacgctttat ccaaggtaac acccagatca gtcgggatat cagataaaga aatggtactt
    17761 acaagagtat tcacgtcagt atcaatgacc gaaaccgtgc tgtctccagt gtttgcagta
    17821 aacacgtaag atcgctgatc cggcgccggt acaagtacaa tcgtccccgt caccgataaa
    17881 ggactgccgt agaacggcgg aacgacaaca aggttctcga tcgtgatgtc actgaaatcc
    17941 gggcaatcat ccgggttatc agaataatag acgacttgat cgatctctgc attgtgaatg
    18001 acagaaacag ccccgtcccc ttgtccatat tgatttctta caggtgagac actgacaaga
    18061 agcgtaacgg tcccttgcag acgcacagca tattgaacac cgatatcttc tggttccggc
    18121 ccagtctgga ttaagcaagg ctcactgata caggacaaat tgtctgtact ccacgtaacc
    18181 gctgcagctg cttcggcaga atcaatagtg aacccctcag gaatgtcaat cggcacttga
    18241 aacagcgctt ctcggctgat ctcctcatca caaaagcaga aacaattttc ctgaaaagca
    18301 gaaagatcat tttttttcat aatgtcacgt ccttttaaaa atgcacaaca tgcatttggt
    18361 taaatcgcaa tgtcactcgg tgaaacgcca agcgatatga cagtttccac agaataatca
    18421 tccgtgttgt aaacagtgat gctttgctct ataaaatgag ttgcatacag aaattcgcca
    18481 tttggggtaa acgcaaagtc gcttgccgat tgcggaagat ttcctattac gcctgcacca
    18541 cttggactga cggaatatag attgtgagtg aaatcatcaa acaaatacaa ccctgatccg
    18601 ctcttaaaca ttcgatattc accctcatac tccagctctt gggtgctact gatcgtaaac
    18661 gtatctaaat caataatcgt caaaaaattg aggaattgat cttgttctaa tacataggca
    18721 taccgctccg gcggctttgt ttctatggaa tttacgataa gttcccgttc aatcgttcct
    18781 gtgacttcac cggtagataa gtccactttt tgcactaatc caaaatcaag aacataggcg
    18841 aacaacccat tgggatcaat tgcaatatca tacccttcaa caggaataga cctttctacg
    18901 gcagacgttt caattctgat cacataaatg gcattaccgg cgagaacata tgcgaaatca
    18961 tgttcaggca taaatttaat tgtttcaggc ggctgatcta gcggaatgga tgcagtaaca
    19021 gtcaatgtgc cattatcgat gacagaaatg acactattgt tcaaatgcaa aacaaacgta
    19081 gaggctttat ctggcgtaat ttctatacct gttggctcgt atgggagaga aatggttgtt
    19141 ataacggtat gagtattcgt atcaattacg gaaaccgact gatcatctgg attcgctgta
    19201 aatgcataaa caggctccgg ctctggttcc ggggcgagca caatcgttcc tgtcaccgat
    19261 aaaggactgc cgtaaaacgg cgggacgaca acaagatttt cgatcgtgat gtcacttaaa
    19321 tccgggcaat catccggttc atcagagtaa tagacgactt gatcgatctc tacattgtga
    19381 atgacagaaa cagctccctc cccttgtcca tattggtttc gcacaggtga gacactgaca
    19441 agaagcgtga cggttccctg caggcggact gcaaaatgga tttcgatctc atcaggcccg
    19501 ggtccagtct gaatgaagca gcgttcactg acacaggata ggctgtctgc gttccacgtg
    19561 acattcgcta ccgcttcagc aggatcaaca acaaacccct caggcacttc tatcggcgct
    19621 tgaaacatgg cttcacggct ggcttcttcc tcacaaaaac ataaacaatc ctcttgctgt
    19681 ctgacggctt tttctttaaa agaacgctca atcttcttca catgctcact tccttctcag
    19741 aaatagctgc taagcgcagc agtaatagag tatggggaca aaaaggtttt gcttgtacaa
    19801 aagttctaag ccaaaagtgt ttttttaaac tgaaaacggg taaaaagaaa aagagttatt
    19861 tacaaattat gttttatagc aggaatgtca ggttatataa aataaaaaag acttcataag
    19921 gaggatttat ttatacaagc agccttatta cactacttat ataagttccc aagcttctct
    19981 gggtaaataa aaggaggatc acaatgaaaa ggaatacaac cttgatcgga atcgtttctt
    20041 tgctattact attaatgctg tctgcatgcg gcagcgataa tcaagacaaa aaatcagatc
    20101 aaacgatgaa tatggacgac acacatactc attctgagtc cagtgagatt ccggaaggcc
    20161 tgacagcagc acagcaccca acttataaag ttggaagcca agccatcatc aaagcggatc
    20221 acatgaaagg catgaagggt gccgaagcaa ccattacagg tgcctatgat acgacggcct
    20281 atgctgtttc ctatacaccg acaaccggcg gaacaagagt ggaaaatcat aaatgggtga
    20341 ttcaagaaga aataaaaaat gccagtgatg aaacattaaa acccggaacg gacgtgatta
    20401 tagaagcgga tcatatgaag ggaatgaagg gtgtaacagg gaaaatcgat tcagctgaga
    20461 aaacgactgt ctatacggtt gattacaccc cgacaactgg cggagaaaaa gtgaaaaatc
    20521 acaagtgggt aacagaaagt gaactatctt caaaataaag gcagaatatg atgatgaact
    20581 gttaaacaaa ttggccctat ccaatatgtt taacagttta tttttattgt gctttgatat
    20641 ggccgggaga gagagagcgt ttccactatt cggtcacgca aaaaaatttg cggttttttt
    20701 gcgcttccaa acaaaacaaa aatgataaaa tatgacatat atagaacaca gaaaggaggt
    20761 atttataata gagacaaata taatttcttc gtcagcagtc ggagaaaaaa ttaacgaatg
    20821 gtacatgtac atacgtaaat tcagcatacc tgacgcagag tacttacgga gagaggttaa
    20881 agaagaactt gatcaaatgg aagaagatca agacttgctt ctgtattatt cactgatgga
    20941 atttcgccac aacctcatgc ttgaatacct tgaaccgtta gaaaagctgc ggattgaaga
    21001 gcagccaaga ctgtctgatt tgttaatcga gattgacaaa aaacagtcac ggctcaccgg
    21061 attactcgat tattacttta atttcttcag aggaatgtat gaattagacc gccgcgagta
    21121 cctattggcc attcagtttt tcaaaaaagc cgagcataaa ctgacttttg tcaaggatcc
    21181 tattgaaaag gctgagtttt tctttaaaat gtctgagtct tattattata tgaaacaaac
    21241 gtatttttct atggactatg ctcgacaagc ctatgaaatt tacaatgaac atacaacata
    21301 taacataagg ctgctacaat gccattcttt atttgctaca aattttttag atttgaagca
    21361 atataacgaa gcaatttccc attttaaaaa agctttttcg atggctcaag cagaacaaca
    21421 gccgcaattg atgggtagaa cactttataa cattgcactt tgcaaacaaa gtcaaaaaga
    21481 gtatgaatcg gcaattgaat atattgaaag agctatttta gtttttgaaa atgctggaat
    21541 tatcccttcc ctgccgcaat cttatttttt gattacagat atttattata aacaaggcaa
    21601 gattaataaa
//
