LOCUS       NZ_CP023477            20870 bp    DNA     circular CON 18-JUL-2024
DEFINITION  Streptococcus mutans strain LAR01 chromosome, complete genome.
ACCESSION   NZ_CP023477
VERSION     NZ_CP023477.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus mutans
  ORGANISM  Streptococcus mutans
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2088369)
  AUTHORS   Abranches,J., Lemos,J., Kajfasz,J. and Aviles-Reyes,A.
  TITLE     Whole genome sequence and phenotypic characterization of a Cbm+
            serotype e strain of Streptococcus mutans
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2088369)
  AUTHORS   Abranches,J., Lemos,J., Kajfasz,J. and Aviles-Reyes,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2017) Oral Biology, University of Florida, 1395
            Center Drive POBOX 100424, Gainesville, FL 32610, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: celera v. 9/01/15
            Genome Coverage                   :: missing
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002995555.1-RS_2024_07_18
            Annotation Date                   :: 07/18/2024 01:10:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,086
            CDSs (total)                      :: 2,002
            Genes (coding)                    :: 1,930
            CDSs (with protein)               :: 1,930
            Genes (RNA)                       :: 84
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 41 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 29 of 72
            Pseudo Genes (multiple problems)  :: 25 of 72
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:47:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1473053
            Orig. end                         :: 1493923
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023477.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Dr. Jacqueline Abranches.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20870
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="6"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20870
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20870
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10870](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10870)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            130..1065
                     /locus_tag="CO204_RS07460"
                     /old_locus_tag="CO204_07425"
     CDS             130..1065
                     /EC_number="1.3.98.1"
                     /GO_function="GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803938.1"
                     /locus_tag="CO204_RS07460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07425"
                     /product="dihydroorotate oxidase"
                     /protein_id="WP_019323126.1"
                     /transl_table=11
                     /translation="MVSTHTTIGSFDFDNCLMNAAGVYCMTREELAAIDHSEAGSFVTK
                     TGTLEERAGNPQPRYADTKLGSINSMGLPNLGISYYLDYVTELQKQPDSKNHFLSLVGM
                     SPEETHTILKMVEASKYQGLVELNLSCPNVPGKPQIAYDFETTDQILSEVFTYFTKPLG
                     IKLPPYFDIVHFDQAAAVFNKYPLTFVNCINSIGNGLVIEDETVVIKPKNGFGGIGGDY
                     VKPTALANVHAFYKRLNPSIQIIGTGGVKTGRDAFEHILCGASMVQIGTALHQEGPQIF
                     KRITKELKAIMTEKGYETLEDFRGKLNAMA"
     gene            complement(1128..1283)
                     /locus_tag="CO204_RS07465"
                     /old_locus_tag="CO204_07430"
     CDS             complement(1128..1283)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321497.1"
                     /locus_tag="CO204_RS07465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07430"
                     /product="hypothetical protein"
                     /protein_id="WP_002263254.1"
                     /transl_table=11
                     /translation="MKFIIIVLIVFSIVKIISIIWVSKIMKPKPMTPKEIEEYDRKEDQ
                     KDGFDF"
     misc_feature    1266..1281
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.49"
                     /tool="antismash"
     misc_feature    complement(1269..1284)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.33"
                     /tool="antismash"
     gene            complement(1346..1822)
                     /locus_tag="CO204_RS07470"
                     /old_locus_tag="CO204_07435"
     CDS             complement(1346..1822)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1266: hydrogen
                     peroxide sensitive repressor"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834882.1"
                     /locus_tag="CO204_RS07470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07435"
                     /product="Fur family transcriptional regulator"
                     /protein_id="WP_002263255.1"
                     /transl_table=11
                     /translation="MGLHSHNNDPNKDVYDHVLTHLKEKHIRITKTREAVISYMINSRR
                     HPSAEQIHKDLLPQYPSMSLATVYNNLKVLIDEGFVVELKLSNDNTAYFDFMGHQHLHV
                     VCESCGKITDFVDTDISHIKQEAYKQTNYVITRAQLLIYGICPDCQSKKTKKAD"
     gene            2041..2652
                     /locus_tag="CO204_RS07475"
                     /old_locus_tag="CO204_07440"
     CDS             2041..2652
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299086.1"
                     /locus_tag="CO204_RS07475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07440"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_106006800.1"
                     /transl_table=11
                     /translation="MHRKNISDAANTLFISKGITDKTMDNIAKLAGYSKATLYVYFENK
                     EEIFFSLVYKHAKWLYETIEKIIQIQPSTQEEWQKNYLKICFALQKLCENYPIYFDGMI
                     GHINVDMTSKETPQVYRDIYQLGLDINQLINKLIEDGVHLNYLQTELDFNRSTLFFWSA
                     LSGIIRMAENKKEYYHLLGLDNKTFLEEEFLTLLACYKKG"
     gene            2659..3777
                     /locus_tag="CO204_RS07480"
                     /old_locus_tag="CO204_07445"
     CDS             2659..3777
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803937.1"
                     /locus_tag="CO204_RS07480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07445"
                     /product="hypothetical protein"
                     /protein_id="WP_002263257.1"
                     /transl_table=11
                     /translation="MKKKVIITTIAAFLFILFSVGAIIFTIGKTANTQTNIQLERTSSD
                     IEHALYYASFAANSHNTQSWKVNLDPKQKRLGVFLNNKRSLNVVDPNNRELYISIGCYI
                     QSLKKSFEAYGYNVSISNIAPSKENKYQVVLINYQKLKNNKINNKQLDIIQKRHTDKRK
                     FQKKPINRTVVSSLIKKYNNVYYYAKGSKTFKYLQKGSLAAAAKQYKNQDFLKEQGKWL
                     RFSNQEVEKKQDGISGDMLGLNPIIKTLYYLTSNHKNATSNNFVKQSKNTLINQVENCA
                     GFFVITGEQNISKWIAVGEKSQAFWYDCVRNNIAVQPISAMIEIPSYNQKLQQNLGKSQ
                     PVQLILRVGYVNSYGKNVGPRRNLKDYITVKK"
     gene            3944..4105
                     /locus_tag="CO204_RS10995"
                     /old_locus_tag="CO204_07450"
     CDS             3944..4105
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024729.4"
                     /locus_tag="CO204_RS10995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07450"
                     /product="IS3 family transposase"
                     /protein_id="WP_002310103.1"
                     /transl_table=11
                     /translation="MFFDEINVYEKSFKSLDKLEKAITNYIFDYNKKRIKTKLKGLSPV
                     QYRTKSLQ"
     misc_feature    3945..3954
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            complement(4198..4473)
                     /locus_tag="CO204_RS07490"
                     /old_locus_tag="CO204_07455"
     CDS             complement(4198..4473)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /locus_tag="CO204_RS07490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07455"
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_002262099.1"
                     /transl_table=11
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQL
                     IGFGNFEVRERAARKGRNPQTGEEIKIKASKVPAFKAGKALKDAVK"
     gene            complement(4570..5169)
                     /locus_tag="CO204_RS07495"
                     /old_locus_tag="CO204_07460"
     CDS             complement(4570..5169)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002266412.1"
                     /locus_tag="CO204_RS07495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07460"
                     /product="YpmS family protein"
                     /protein_id="WP_002262100.1"
                     /transl_table=11
                     /translation="MKQRRTGNKKNWWKWAFLLLLALNIAFWGVIISRVLSGYHSNTIT
                     SQTVKNPVKVGTITTTKEQLNQTLASYLNDYQSKGMTYSVQLTSTNIEFQGTYKLLGYN
                     VPLYIYFEPYQLKSGAVQLKVTSFSVGNLPLPASEVLSYIKSSYKLPNFVDVIPEKSVV
                     NINLQKIDNDAGIYLKSTAINLVSDEINFDILKKKR"
     gene            complement(5144..6001)
                     /locus_tag="CO204_RS07500"
                     /old_locus_tag="CO204_07465"
     CDS             complement(5144..6001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312511.1"
                     /locus_tag="CO204_RS07500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07465"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_002274141.1"
                     /transl_table=11
                     /translation="MSKKIPKGPAFFLANLLIFSLLFYFFIPTAKLSFKNSDQKSSLNK
                     SKATSFHYIAIGDSLTQGVGDTTDQGGFIPLLSQELKSNYHYNVLSSNYGVSGNTSQQI
                     LIRMRKERKIQKSLNKANLMTLTVGGNDVMTVVRKGLTNLKVSSFRQPAKTYQKHLRKI
                     IQVARRRNKNLPIYIIGIYNPYYLNFPNMTQMQDIIDNWNKGTQKVVAEYRNVYFVPIN
                     DLLYKGVNGEQKAVGTSDSEAESGEVTNDALSEGDRFHPNNVGYQIMSKAIMEKISETK
                     KNWK"
     gene            complement(5994..6833)
                     /locus_tag="CO204_RS07505"
                     /old_locus_tag="CO204_07470"
     CDS             complement(5994..6833)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264715.1"
                     /locus_tag="CO204_RS07505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07470"
                     /product="DegV family protein"
                     /protein_id="WP_002288665.1"
                     /transl_table=11
                     /translation="MSKIKIVTDSSITIEPDLVEALDITVVPLTVMVDGIVYSDNDLKK
                     DGKFLSLMRNSKSLPKTSQPPVGLFAETYEKLIKEGAEQIVAIHITHSLSGTLEASRQG
                     ANIAGADVTVLDSAFTDQAMKFQVIAAAKLAQKGSSLEEILARVEEVKKKTELFIGVST
                     LENLVKGGRIGRVTGLISSLLNIRVVMELKNHDLNPIAKGRGNKTFNKWLDNLIATIKD
                     RKIAEIGISYAGTSDFANGLKDKLQAYVEKDIAVLETGSIIQTHTGEGAFAVMVHYE"
     gene            complement(7055..8713)
                     /gene="recN"
                     /locus_tag="CO204_RS07510"
                     /old_locus_tag="CO204_07475"
     CDS             complement(7055..8713)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312509.1"
                     /locus_tag="CO204_RS07510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07475"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_019313124.1"
                     /transl_table=11
                     /translation="MLLEIAIKNFAIIEEISLNFERGMTVLTGETGAGKSIVIDAMNMM
                     LGSRASIDVIRHGSPKAEIEGFFSVDKNPSLEQLLADQGIAFSDELIIRREILQNGRSI
                     SRINGQMVNLATLRAVGQYLVDIHGQHDQEELMRPQKHIQLLDEFGDEVFQVSKQHYQD
                     LFDRYRDLRKHVLNKRKNEQEHQARIEMLEYQIGEIEAADLQSGEDTKLLKQRDKLMNH
                     KLIVETLTNAYVLLDNEDFSSLTNVRSAMNDLQSLEEYDAEYKDLSNNLSESYYILEDV
                     SKRLETILDHMDFDANTLVKLEARLDVINTITRKYGGSVDDVLAYFDNISKEYNHLTGN
                     DLAFDDMERELKVLERSLLEAAAQLSQKRHAIAETLSQEIKQELKDLYMDKADFKVVFT
                     KGKFNREGNETVAFHISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRREDKTSIVFD
                     EVDTGVSGRVAQAIAQKIYKIGNHGQVLAISHIPQVIAISDYQYFIEKQSSKATTVSTV
                     RLLNQEERIEEIAKMLAGDNVTQAARQQAKELLKK"
     misc_feature    8726..8740
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            complement(8730..9194)
                     /locus_tag="CO204_RS07515"
                     /old_locus_tag="CO204_07480"
     CDS             complement(8730..9194)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002278192.1"
                     /locus_tag="CO204_RS07515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07480"
                     /product="arginine repressor"
                     /protein_id="WP_002264713.1"
                     /transl_table=11
                     /translation="MKKRERLELIKKIVLENEIETQKELVKLLENEGLQATQATISRDI
                     NEVGIIKVPASNGRYIYGLSKEISKKEESTPKPAEKAVKFISDQVAGLEHLIHIDVVPG
                     NSYLLKRFLLERFEGLIFSLLADDDSLLLIVKNAKDSDRIRQEIKSWMAN"
     gene            complement(9181..10008)
                     /locus_tag="CO204_RS07520"
                     /old_locus_tag="CO204_07485"
     CDS             complement(9181..10008)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834880.1"
                     /locus_tag="CO204_RS07520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07485"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_002275375.1"
                     /transl_table=11
                     /translation="MPKERVDVLAYKQGLFNTREQAKRGVMAGLVVNVINGERYDKPGE
                     KIDEATELKLKGDKLKYVSRGGLKLEKALKVFAISVDGQITLDIGASTGGFTDVMLQNG
                     AQLVYAVDVGTNQLVWKLRQDERVCSMEQYNFRYAESSDFERGQPTFASIDVSFISLNL
                     ILPALAKILTDGGQVVALIKPQFEAGREQIGKHGIVKDKSVHETVLETVTTFATNYGFT
                     VKELDFSPIQGGHGNIEFLAYLEKSAQAQNQVLTKIKSIVEQAHKEFKKNEET"
     gene            complement(10001..10870)
                     /locus_tag="CO204_RS07525"
                     /old_locus_tag="CO204_07490"
     CDS             complement(10001..10870)
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002279431.1"
                     /locus_tag="CO204_RS07525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07490"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_002292151.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-51, bitscore:
                     172.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDKIKSINQAIKHYYAQTHVSQDLVEAVLYSVAAGGKRIRPLLL
                     LEILQGFGLVLTEAHYQVAASLEMIHTGSLVHDDLPAMDNDDYRRGQLTNHKKFGEATA
                     ILAGDSLFLDPFGLLAKADLRADIKIKLVAELSDAAGSYGMVGGQMLDIKGEHVQLNLD
                     QLAQIHANKTGKLLTFPFVAAGIIAELSEKALARLRQVGELVGLAFQVRDDILDVTASF
                     SELGKTPQKDIEADKSTYPSLLGLDKSYAILEDSLNQAQAIFQKLALEEQFNATGIETI
                     IERLRLHA"
     gene            complement(10867..11088)
                     /locus_tag="CO204_RS07530"
                     /old_locus_tag="CO204_07495"
     CDS             complement(10867..11088)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262107.1"
                     /locus_tag="CO204_RS07530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07495"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_002262107.1"
                     /transl_table=11
                     /translation="MSNKKKTFEENLQDLEEIVNQLETGEIPLEEAITQFQKGMALSKD
                     LQKTLESAEKTLVKVMQADGSEAEMDEL"
     gene            complement(11063..12406)
                     /gene="xseA"
                     /locus_tag="CO204_RS07535"
                     /old_locus_tag="CO204_07500"
     CDS             complement(11063..12406)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678150.1"
                     /locus_tag="CO204_RS07535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07500"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_002266419.1"
                     /transl_table=11
                     /translation="MSDYLSVSSLTKYLKLKFDRDPYLERVYLTGQVSNFRRRPNHQYF
                     SLKDEKAVIQATMWSGIYRKLGFELEEGMKINVIGRVQLYEPSGSYSIIIEKAEPDGIG
                     ALAVQFEQLKKKLAEAGYFDDRHKQRLSQFVKKIGVVTSPSGAVIRDIITTVSRRFPGV
                     DILLFPTKVQGEGAAQEVADNIRLANERTDLDLLIVGRGGGSIEDLWAFNEEIVVQAIF
                     ESHLPIISSVGHETDTTLADFAADRRAATPTAAAELATPVTKADLLAFLKERQMRSYQA
                     VMRLIRQKDEQVKKLQRSVIFRQPERLYDAYVQKLDHLRTHLLTKVRQVYDVYDSKEHL
                     LRQRLLSLNLSGCIQRYQAQLKQDQRLLLSHMSSQYDSKLARFEKAQDALLSLDTTRIV
                     ARGYAIVQKDNHIIQSTQQIKKGDRLHLEMKDGQVQVEVENVKQEENI"
     misc_feature    complement(12736..12751)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.6"
                     /tool="antismash"
     gene            12849..14591
                     /gene="lytS"
                     /locus_tag="CO204_RS07540"
                     /old_locus_tag="CO204_07505"
     CDS             12849..14591
                     /codon_start=1
                     /gene="lytS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262109.1"
                     /locus_tag="CO204_RS07540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07505"
                     /product="two-component system sensor histidine kinase
                     LytS"
                     /protein_id="WP_002264709.1"
                     /transl_table=11
                     /translation="MLMILLFQRLGIIMILAFLLVNNSYFRQLIEERSKREKLVLIIIF
                     GIFVIISNMTGIEITSDKSLVERPILTTISHSDSLANTRTLVITTASLVGGPLVGTVVG
                     FIGGVHRFFQGNFSGAFYIVSSALVGYISGRLGDQLKTNNLYPSTSQVIVISIIAESIQ
                     MLFVGFFTGWDLVKLIFIPMMLLNSLGSTLFLAILKTYLSNERQLRAVQTRDVLDLTQQ
                     TLPYLRQGLSQQSATKVCNIIKQHTNFDAVGLTDRTNVLAHIGVGQDHHIAGQAVKTDL
                     SKSVILNGQPQIALDKTAIACPDQSCLLNSAIVVPLKINNETVGALKMYFSGDKKMTEV
                     EENLALGLAQIFSGQLAIGIAEEQNKLANIAEIKALQSQINPHFFFNAINTISALIRLD
                     ANKARYALMQLSTFFRTSLQGGQDREITLEQEKAHVDAYMNLEKLRFPDKYQLDYHITV
                     STKMTLPPFGLQVLVENAVRHAFKERKKDNHICISITDQGEFYKVAVSDNGQGISPNMI
                     DKLGQETVSESKGTGTALVNLNNRLNLLYGSASQLHFDSTDQGTTVWYEIPYQKGDKDE
                     HFNS"
     gene            14572..15306
                     /gene="lytR"
                     /locus_tag="CO204_RS07545"
                     /old_locus_tag="CO204_07510"
     CDS             14572..15306
                     /codon_start=1
                     /gene="lytR"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262110.1"
                     /locus_tag="CO204_RS07545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07510"
                     /product="two-component system response regulator LytR"
                     /protein_id="WP_002268049.1"
                     /transl_table=11
                     /translation="MNILILDDEMLARQELTFLIQQSKELDHPDIFEAEDISSAEKILF
                     RQQIDLIFLDISLSEENGFTLANQLEQLAHPPLVVFATAYDHYAVKAFESNAADYILKP
                     FEQDRVDKALAKVKKIQHLSTIDETATTEKKGMELLTLTLADRSIVLKMPDIVAASIED
                     GELTVSTKNTSYTIKKTLNWFKTRAKTNYFLQIHRNTVVNLEMIQEIQPWFNHTLLLVM
                     VNGEKFPVGRSYMKELNAHLTL"
     misc_feature    15370..15382
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    15418..15429
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.05"
                     /tool="antismash"
     gene            15482..15949
                     /gene="lrgA"
                     /locus_tag="CO204_RS07550"
                     /old_locus_tag="CO204_07515"
     CDS             15482..15949
                     /codon_start=1
                     /gene="lrgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262111.1"
                     /locus_tag="CO204_RS07550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07515"
                     /product="holin-like protein LrgA"
                     /protein_id="WP_002264708.1"
                     /transl_table=11
                     /translation="MKHTSKVTQSKSAPMFIQMSIYAAILLVSQLISELLPKALPIPTT
                     VIGLILMYVLLCSHIIKIEWVDSLGSLLISMIGFMFVPSGISLAANLNILKAEGLQLVA
                     VISLSTILMLVIVTYITSIILSIKKVNVASLWEKWTAHSFEKKFSKKVEGK"
     gene            15951..16682
                     /gene="lrgB"
                     /locus_tag="CO204_RS07555"
                     /old_locus_tag="CO204_07520"
     CDS             15951..16682
                     /codon_start=1
                     /gene="lrgB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271503.1"
                     /locus_tag="CO204_RS07555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07520"
                     /product="antiholin-like protein LrgB"
                     /protein_id="WP_002264707.1"
                     /transl_table=11
                     /translation="MALLKSPIFGICFSLILYTIGQDLFKKSKGFFLLQPLFFAMVAGI
                     IVLVLLAKGLGTDVKTLYTQAYKPGGDLIFWFLNPATIAFAVPLYKKNDAVKKYWKEII
                     SSLIIGMVVSLVIIVAISKAIGLSQASTASMLPQAATTAIALPIAHAIGGNTAITAMAC
                     ILNAVIIYALGKKLVAFFHLNKSEIGVGLGLGTSGHTVGAAFALELGELQGAMAAIAVV
                     VIGLVVDLVIPIFSYMIGLVH"
     gene            complement(17007..17840)
                     /locus_tag="CO204_RS07560"
                     /old_locus_tag="CO204_07525"
     CDS             complement(17007..17840)
                     /GO_function="GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322331.1"
                     /locus_tag="CO204_RS07560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07525"
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="WP_002274136.1"
                     /transl_table=11
                     /translation="MIIDDLLTKKIIKPRPLNSHKGTFGRVLLIGGNYPYGGAIIMAAL
                     ACVNSGAGLVTVATHKDNITALHSHLPEAMAFDMVEKDRLSEQITAADVVLMGPGLAED
                     DLAQTTFDVVWQAIKPKQILIIDGSAINLLAKRKPAIWPTKQIILTPHQKEWERLSGLT
                     IPEQIEAATQTALAHFPKETILVAKSHQTKIYQGQKIGHIQVGGPYQATGGMGDTLAGM
                     IAGFVAQFHTDRFEVAAAAVFLHSYIADQLSKEAYVVLPTRISAEITRVMKEMSE"
     gene            complement(17837..18691)
                     /locus_tag="CO204_RS07565"
                     /old_locus_tag="CO204_07530"
     CDS             complement(17837..18691)
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263561.1"
                     /locus_tag="CO204_RS07565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07530"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_002264705.1"
                     /transl_table=11
                     /translation="MTEIIDGKALAQKLQLHLANKVEQMKEKHGLVPGLVVILVGDNPA
                     SQVYVRNKERSAIKAGFKSETIRLSDSISEEELIEIIEGYNQDPSFHGILVQLPLPAHI
                     NDKKIILAIDPHKDVDGFHPMNTGHLWSGRSMMVPCTPAGIMEMLSAYHVDLEGKHAVI
                     IGRSNIVGKPMAQLLLEKNATVTLTHSRTKHLSEVTRCADVLIVAIGQGNFVTEEFVKE
                     GAVVIDVGMNRDKNGKLIGDVNFDHVAQKASLITPVPGGVGPMTITMLLEQTYQAALRS
                     VTK"
     gene            complement(18812..18958)
                     /locus_tag="CO204_RS07570"
                     /old_locus_tag="CO204_07535"
     CDS             complement(18812..18958)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299875.1"
                     /locus_tag="CO204_RS07570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CO204_07535"
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="WP_002264704.1"
                     /transl_table=11
                     /translation="MSTFIIAILIAAGAFLGIRHYIKQKGSCGDCDCACPVKDEMKKSS
                     KTH"
ORIGIN
        1 aaaagattga aatctctctt agataaagga gttaatcatt caaatcagca agaaaaggaa
       61 aggcaattga gcttgcggtt gaccttatct agtgttacaa tagaaaaaat tcattatttt
      121 ggaggttcca tggtttcaac tcatacaaca attggctctt ttgactttga taattgtctc
      181 atgaatgctg caggggttta ttgcatgaca cgtgaagaat tagcagctat tgatcattcg
      241 gaagcaggtt cttttgttac caagactggt acgctagaag aacgtgcagg aaaccctcaa
      301 ccccgctatg ctgacacaaa attaggctct attaattcaa tgggcctgcc taatctaggt
      361 attagctatt atttagacta tgtcacagaa ttgcaaaaac agcccgatag caaaaatcac
      421 tttttatccc tagttggcat gtcgccagaa gaaacccata ccattcttaa gatggttgaa
      481 gccagcaaat atcaaggttt ggtggaactc aatctttcct gtccaaatgt tcccggtaaa
      541 ccacaaatcg cctatgattt tgaaacaacg gaccaaatcc tttcagaagt tttcacttac
      601 ttcactaaac cactaggtat caagttacca ccttactttg atattgtaca ctttgatcaa
      661 gcagctgctg ttttcaataa ataccctctg acatttgtta attgtattaa ttctattgga
      721 aacggcttag ttattgaaga tgaaacggtc gtcattaaac caaaaaatgg ctttggaggc
      781 attggtggcg attacgtcaa accaacagcg ctagccaatg ttcatgcttt ttacaagcgc
      841 ctcaaccctt ccatccaaat tatcggaacc ggcggtgtca aaacaggtcg cgatgctttc
      901 gaacatattc tctgtggcgc cagcatggtt caaatcggga cagctcttca tcaagaaggt
      961 cctcaaattt tcaaacgtat tactaaagag ttaaaagcca ttatgacgga aaaaggttat
     1021 gaaaccttgg aagattttcg tggcaagctg aatgctatgg cttaaagaaa tctttttatt
     1081 tctgtatacc aaaagacctg actgagaatc tcctcagtca ggtcttttta aaaatcaaaa
     1141 ccatcttttt gatcttcctt gcgatcatac tcctcaattt cttttggagt catcggcttt
     1201 ggcttcatta ttttacttac ccaaataata ctaatgattt taacaataga aaacactatt
     1261 aaaacaatga taataaattt catttaatga ctcacctcct atttcccata tgataagttt
     1321 tctctctaga taatcaataa gcaaattaat cggctttttt agttttcttg ctttgacagt
     1381 ctggacaaat accataaatc aaaagctgtg ctctcgtaat cacataattt gtctgcttat
     1441 atgcttcttg cttgatatga gaaatatcag tgtctacaaa atcagtaatc ttaccacaag
     1501 actcacaaac aacatgcaaa tgctgatgcc ccataaaatc aaaataagct gtattatcat
     1561 tgcttagctt taattcaaca acaaagcctt catcaatcag gactttcaaa ttattataga
     1621 ccgttgctaa actcatactt ggatactgag gaagaagatc tttatgaatt tgttctgcac
     1681 tcggatgacg gcgggagtta atcatgtaag aaataacagc ttctcgtgtt ttagtaatac
     1741 gaatatgctt ttcttttaaa tgcgttaata catgatcata aacatcctta ttcggatcat
     1801 tattatgaga atgcagtccc atttttgact ccttcgttat tctttttttc tattatacac
     1861 tatttttaaa gatacagaaa aattagtgcc tagcatcatc aagtagcctt tacttttcct
     1921 aaatgataaa aaatatgcaa aaaactgtct atcaatttta tctctaaaaa tcattcaaac
     1981 aatctctagg ataattaata caaagatgtt taaaattgac aaaaaaaaga acctgctctt
     2041 attcatcgta aaaatatttc agatgctgct aacacactct ttatcagtaa aggtattact
     2101 gataaaacaa tggataatat tgctaaatta gctggatata gtaaagcaac tttatacgtt
     2161 tattttgaaa ataaagaaga aatctttttc tcattagttt ataaacatgc caaatggctt
     2221 tacgagacta ttgagaaaat tattcaaatt caaccaagca ctcaagaaga gtggcagaaa
     2281 aattatttaa aaatttgttt tgcattgcaa aaactatgtg aaaactatcc aatatatttt
     2341 gacggaatga ttggtcatat caatgttgat atgacctcta aagaaactcc tcaagtttat
     2401 agagatattt accaattagg gttagatata aatcagttaa ttaacaaact tattgaagat
     2461 ggtgttcact taaattatct tcagacagaa ttagacttta accgatcaac tctttttttc
     2521 tggagtgcac tatcgggtat cattcgtatg gcagaaaaca aaaaagaata ttatcactta
     2581 cttggtcttg ataacaaaac ctttttagaa gaagaatttc taactttatt agcatgttac
     2641 aagaaaggat aaaggaacat gaagaaaaaa gttattatta caacaatagc agccttttta
     2701 tttattcttt ttagtgtagg agccattatt tttactattg gaaaaaccgc taatacccaa
     2761 actaatattc aattagaaag aacttcatca gacatcgaac acgcgttata ctatgcttct
     2821 ttcgcagcta attctcataa tactcagagt tggaaagtta atttagatcc taagcaaaag
     2881 agattagggg tttttctaaa taataagcgt tctttaaatg tcgttgaccc aaataatcga
     2941 gaactttata tttcaattgg ttgttatatt caatctttaa aaaaatcatt cgaagcttat
     3001 ggatataatg ttagcatttc taatattgct ccttctaaag aaaacaaata tcaagttgta
     3061 ttgataaatt atcaaaaatt aaaaaataat aaaattaaca ataaacaatt ggatatcatc
     3121 caaaaacgtc atactgataa aagaaaattt cagaaaaaac caattaatag aacagtcgtt
     3181 tcaagtttaa ttaaaaaata taataatgtt tactactatg ctaaggggag taaaacattt
     3241 aaatatctac aaaaggggag tctcgcagct gctgctaaac agtataaaaa tcaagatttt
     3301 ttaaaagaac agggaaaatg gttgcgtttt tctaatcaag aagttgaaaa aaaacaagat
     3361 ggtatctcgg gtgatatgct agggttaaat cctataatta aaacccttta ttatctaaca
     3421 agtaatcata agaatgccac gagtaataat tttgttaaac agagtaagaa tactttaatt
     3481 aatcaagtag agaactgcgc aggttttttt gtaattacag gtgaacagaa tatttctaaa
     3541 tggattgctg ttggtgaaaa atcgcaagct ttctggtatg attgtgttag aaataacatt
     3601 gcagttcaac cgattagtgc catgattgaa attccctcct ataatcaaaa gttacagcag
     3661 aatttaggta aatcacaacc tgttcaatta attttacgag taggttatgt taacagttat
     3721 ggtaaaaatg ttggtcctcg tcgaaattta aaagattata ttactgtgaa aaaataatct
     3781 gctattatta taacttagct atatgacaca gctagaacag gaaataacaa acaagtatta
     3841 tggtagcact cactgtaaaa gaaaacatgc taatagaaca ttaaaaagac catagcaaac
     3901 tgacttgcac cctaaaagtt ggacagaaaa tctaacgata ggggtgtttt ttgatgaaat
     3961 taacgtatat gaaaagtctt tcaaatcgct cgacaaactt gagaaagcca tcactaacta
     4021 catttttgac tacaacaaga aacgaatcaa gacaaaacta aaaggactca gccctgtgca
     4081 atacaggact aaatcccttc aataatttct tgtccaactt tttggggtca gtacagaaac
     4141 gtttgtacac tctaaaatct aaagattaaa ttttagaaaa gtacatttgc caaaatctta
     4201 ttttacagcg tctttaagag ctttgccagc tttgaatgct ggaactttag aagctttgat
     4261 tttgatttct tcacctgttt gagggttgcg acctttgcgt gctgcacgtt cgcgaacttc
     4321 aaagttacca aaaccaataa gttgtacttt ttcacccttt gcaaggtaag atgatactgc
     4381 tgagaagaca gcgtctactg ctgcagctga atctttctta gtcaattcag tagcttctgc
     4441 tacttttgca atcaaatctt gtttgttagc catttaacaa atcctccaat atttttataa
     4501 gcctttatag gctttaacag gttctatctt acctaaaaaa cttagatagg tcaagtattt
     4561 aatgccattt taacgttttt tctttaaaat atcaaagttt atttcatcac taaccaaatt
     4621 tatagctgtt gactttaaat aaatgcctgc atcattgtct attttttgca aattgatatt
     4681 aacaacagac ttctctggaa taacatcaac aaaatttggc agtttgtaac ttgatttaat
     4741 ataactaaga acctctgatg ctggcagagg aagattgcct actgaaaagg aagtcacttt
     4801 aagctggaca gctccgcttt ttaactgata aggttcaaaa tagatataaa gaggtacgtt
     4861 ataacctaga agtttataag ttccttgaaa ttcaatgttt gttgaagtca gttgaacact
     4921 gtaggtcata cccttagact gataatcatt caaataactt gccaaggtct gattcaattg
     4981 ttctttagtt gtcgtaattg ttccaacctt aacaggattt tttactgttt gacttgttat
     5041 tgtattagaa tggtaaccgc tcaaaacacg actgataatc actccccaaa aagcaatatt
     5101 gagtgctaat aaaagcaaaa aagcccattt ccaccaattt tttttatttc cagttcttct
     5161 ttgtttcact gattttctcc attattgctt ttgacatgat ttgataacca acattattag
     5221 gatggaaacg atctccttca gaaagggcat cattggttac ttctcctgac tctgcctcac
     5281 tgtcagatgt tccaacagcc ttttgctctc cattaacacc tttataaagt aaatcgttta
     5341 tgggaacaaa ataaacgttt ctatactctg cgacaacctt ttgcgttccc ttattccaat
     5401 tgtcaataat atcctgcatt tgcgtcatat tagggaaatt taaataataa ggattgtaaa
     5461 taccaatgat ataaatggga agattcttat tccttcttct agccacctgg ataatttttc
     5521 gcaaatgctt ctgataagtt ttagctggct gcctaaaaga agatactttt aagtttgtta
     5581 atccctttcg aacaacagtc ataacatcat ttccaccaac tgttaaggtc attaaattag
     5641 ccttattcaa acttttttga atttttctct cttttcgcat ccgtatcaaa atttgctggc
     5701 ttgtattgcc tgaaacacca taattactgc ttaaaacatt atagtgataa tttgatttca
     5761 actcttgcga taaaagggga ataaagccgc cttgatcagt cgtatcaccg actccttgtg
     5821 tcaaagagtc accgatagca atatagtgaa aagatgtcgc tttggatttg tttaatgaag
     5881 atttctgatc gctattttta aaagataact tcgctgttgg aataaaaaaa taaaataata
     5941 agctaaaaat aagaagattt gcaagaaaga aagcaggtcc tttaggaatt tttttactca
     6001 taatgcacca ttactgcaaa agcaccttca cctgtatgag tctgaataat tgaccccgtt
     6061 tctaaaacag caatatcttt ctcaacataa gcctgtaact tgtctttaag accattagca
     6121 aaatctgaag tcccagcata ggaaatgccg atctcagcaa ttttgcgatc tttgatagtc
     6181 gcaatcaaat tatccagcca tttgttaaac gttttattac cgcgtccttt cgcaatagga
     6241 ttaagatcat ggtttttcag ttccataaca actctgatat tgagaagaga actgattaag
     6301 cctgtcacac ggccaattcg tccaccctta accagatttt ctaaggttga gacaccaata
     6361 aaaagttcgg ttttcttttt tacttcttca acccttgcca aaatttcttc tagactgcta
     6421 cccttttgag ctagtttagc agccgcaata acttgaaatt tcatggcttg atctgtaaag
     6481 gcagagtcta gtacagtgac atctgctcca gcaatattag ctccttgacg tgaggcctca
     6541 agtgttccag ataaggaatg ggtaatatga atagcaacaa tttgttccgc cccctcttta
     6601 ataagctttt cataagtttc tgcgaacaga ccaacaggtg gttggcttgt tttagggagt
     6661 gacttactgt ttcgcattaa agaaagaaat ttcccatctt tcttaagatc gttatcagaa
     6721 taaacaatgc cgtcaaccat aacggttaaa ggaacaacag tgatatccaa tgcttcaact
     6781 aaatcgggct cgattgtaat agaagaatca gttacaattt taattttact catttcttat
     6841 cctgcttcat ttcttttcta aatttatatt agtattgtta ttataccaaa taatcaagat
     6901 ttagggaaaa ttttaaaaga cagaaaggat taaaattact ttgctgttaa actttaagat
     6961 agtttaaaat agttctctac aagcaatagt ccaaatcaaa acaaaaagat tgaagtaaga
     7021 gcatatttat taaaatactt tctataccaa tctcttattt ttttaatagt tctttagctt
     7081 gctggcgcgc agcttgggtc acattatccc ctgccaacat cttagcgatt tcttcaattc
     7141 tttcctcttg atttaaaagg cgaaccgttg agacagttgt ggctttactg ctttgttttt
     7201 caataaagta ctgataatca ctgatggcaa tgacttgcgg gatatgggag atagctaaaa
     7261 cttgaccgtg attgcctatt ttgtaaattt tttgagcaat agcctgcgcg acacgtcctg
     7321 aaacacctgt atcaacttca tcaaaaacaa tgctagtctt atcttcacga cgtgaaaaag
     7381 ctgacttaat ggctaacatg agacgagaca gctctccacc agaagcgact ttgaccaaag
     7441 gcttaaagtc ttcgccagga ttagtcgaaa tatgaaaagc gactgtttca tttccctcgc
     7501 gattaaattt tcctttagta aaaacaactt taaaatcagc cttatccatg tagagatctt
     7561 ttagttcctg cttaatctcc tgagacaagg tttccgcaat agcatggcgt ttttgactca
     7621 attgagctgc tgcttctaat agtgagcgct ccaaaacttt tagttctctt tccatatcat
     7681 caaaagcgag gtcatttccc gtcaaatgat tgtattcctt actgatattg tcaaaataag
     7741 ccaaaacatc atcaactgaa ccaccatact tacgcgtgat ggtgttgata acatcaagac
     7801 gtgcttcaag tttaaccaaa gtattggcat caaaatccat atgatccagt atggtctcta
     7861 gacgtttgct aacatcttct aaaatatagt aagattcgct gagattattg gacaaatcct
     7921 tgtactcagc atcatattct tccaaactct gcaaatcatt catagctgaa cgaacattgg
     7981 tcaaactcga aaaatcttca ttatcaagta aaacataagc attggttaag gtctcaacaa
     8041 taagcttatg attcataagt ttatcacgtt gttttaagag cttggtatcc tcaccagatt
     8101 gtaagtctgc tgcttcaatc tctcctatct gatactccag catttcaata cgtgcttgat
     8161 gttcttgctc attcttacgt ttattcaaga cgtgcttacg taagtcccga tagcgatcaa
     8221 ataagtcctg ataatgctgc ttgcttacct gaaatacctc atcaccaaat tcatccaaca
     8281 actgaatatg cttttgcggc cgcatcagtt cttcttgatc atgctgtcca tgaatatcaa
     8341 ctaaatactg cccaacggca cgcagagttg ccagattaac catttgacca ttgatacgac
     8401 taatactgcg cccattttgt aaaatctcac ggcgaatgat tagctcatct gaaaaagcaa
     8461 ttccctgatc agccagtaac tgctctaaag aaggattttt atccacagag aaaaaaccct
     8521 caatctctgc tttaggactg ccatgacgaa tgacatctat gctggctcta ctgcctagca
     8581 tcatattcat ggcatcaatg acaatagact tccctgcacc tgtttcaccg gtcagaacag
     8641 tcattcccct ttcaaaattg agtgagattt cttcaataat agcaaaattt ttaatggcaa
     8701 tttctaaaag catacccact ccttatgatt taattggcca tccaagattt gatttcttga
     8761 cgaattctat cactatcttt agcattttta acaatcaaaa gcaaactgtc atcatctgcc
     8821 agcaagctaa aaataagtcc ttcaaatctc tctagtaaaa aacgtttcaa taaatagcta
     8881 tttccaggaa caacatcaat atgaatgaga tgctctaaac ctgccacctg atctgaaata
     8941 aacttaactg ctttttcagc tggttttggt gttgactctt cttttttgct tatttcctta
     9001 gaaaggccat aaatatagcg accatttgaa gctggtactt taatgatacc gacctcatta
     9061 atatcacggg aaattgtcgc ttgcgttgct tgtaagcctt cgttctctaa aagtttgacc
     9121 aattcttttt gtgtttcaat ttcattttct aaaacaattt ttttaattaa ttctaatcgt
     9181 tcacgtttct tcattctttt taaattcctt atgtgcttgt tcaacaatcg atttaatctt
     9241 agtcaagact tgattttggg cttgagctga tttttctaag taggctaaaa attcaatatt
     9301 gccatgaccg ccctgaatgg gagaaaaatc aagttcttta actgtgaatc cgtaatttgt
     9361 cgcaaaagtt gttactgtct ccaaaacagt ttcgtggact gacttgtcct taacaatacc
     9421 atgtttacca atctgttcac gacctgcctc aaattgcggt ttaattaaag caacaacttg
     9481 accaccatct gttaaaatct tagctaaggc tggtaatatt aaattaagtg aaataaaact
     9541 cacatcaatg gaagcaaaag ttggctgtcc tcgttcaaaa tcgctagact ctgcatagcg
     9601 gaaattgtac tgttccatgc tgcagacgcg ttcgtcttga cgtaatttcc acaccaactg
     9661 attggttcca acatcaacag catagactaa ttgagcacca ttttgcagca tgacgtctgt
     9721 aaaaccaccc gttgaagcgc caatgtccaa agttatctgt ccatctactg aaatggcaaa
     9781 aacttttaat gctttttcca atttcaaacc gccgcgactg acatatttta atttatctcc
     9841 ctttaacttt aactcagtcg cttcatcaat tttctcgccg ggtttatcat aacgttctcc
     9901 attgatgaca ttgacaacca aacctgccat aacacctcgc ttggcttgtt ctcttgtgtt
     9961 aaacagtcct tgtttatagg ctagaacatc cactctttcc ttaggcatgg agacgcaacc
    10021 tttctattat tgtttcaatt ccagtagcat taaattgttc ctctaaagct aatttttgga
    10081 aaatagcttg cgcttgattg agagaatctt ccaaaatggc ataggacttg tccaagccca
    10141 aaagactggg ataggttgat ttatcagctt cgatatcctt ttgtggggtc ttaccaagtt
    10201 ctgaaaaact agctgtcaca tctaaaatat catcacgtac ttgaaaagcc aaaccaacta
    10261 attcacccac ttgacggagc cgagcaaggg ctttttctga taattctgct attattcctg
    10321 cggctacaaa aggaaaagtc aagagttttc ctgtcttatt ggcatgaatt tgagctagtt
    10381 ggtctaaatt gagttgaaca tgttcaccct taatatccaa catttgccca ccgaccatac
    10441 catagcttcc tgcagcatct gacaattctg ctactaactt tatcttgata tcagccctta
    10501 agtccgcctt ggctagcaaa ccaaaagggt ctagaaaaag actgtcacct gccaagatgg
    10561 ctgtcgcttc accaaatttc ttatgattgg tcagctgtcc ccgcctataa tcatcattat
    10621 ccatagcagg caggtcatca tgaacgaggc tgccggtatg aatcatctct agacttgctg
    10681 ccacctgata gtgagcttct gtaagtacca aaccaaagcc ttgcaagatt tccaatagta
    10741 agagaggacg aatccgttta ccgcctgcag caacagaata caagaccgct tcaaccaaat
    10801 cctgagacac atgagtttgc gcataataat gcttaatagc ctgattaatg gatttaatct
    10861 tatctttcac aattcgtcca tttctgcttc actgccatca gcctgcatga ctttgaccaa
    10921 ggtcttttca gcagactcca aggttttctg caaatcttta gaaagcgcca ttcctttttg
    10981 gaattgagta atagcttctt caagaggaat ttcaccggtt tctaactggt tcacaatttc
    11041 ttctaaatcc tgtaaatttt cttcaaatgt tttcttcttg tttgacattt tctacctcca
    11101 cttggacctg cccatctttc atttcaagat gcaagcgatc tccttttttg atctgttggg
    11161 ttgattgaat aatgtgatta tctttttgaa caatagcata gccacgcgcc acaatccgtg
    11221 tcgtatccag tgacaaaagc gcatcttgtg ctttttcaaa acgggctaat ttactatcat
    11281 attggctgct catgtggctt aacaataaac gctgatcttg ttttaattgt gcttgatagc
    11341 gctgaataca ccctgataaa ttaagggaca acaatctttg tctcagcaaa tgttccttgc
    11401 tatcataaac atcataaacc tgccgcacct tggtcaacaa atgtgttctt aaatgatcca
    11461 atttttgaac ataagcatca tagagtcttt caggctgtct gaaaataact gatctttgca
    11521 gtttcttaac ttgttcatcc ttttgtctaa tcagacgcat aacagcctga taagatctca
    11581 tctgtctttc tttaagaaaa gctaataaat cagccttggt cacaggtgtt gccaattcag
    11641 ctgctgctgt tggcgttgct gctctgcgat ctgccgcaaa atcagccaag gttgtatccg
    11701 tctcatgtcc aacgctggaa ataatgggca gatgcgattc aaaaatggcc tgcactacaa
    11761 tctcctcatt aaaagcccag agatcttcaa tagaaccccc accacgacca acaatgagca
    11821 ggtctaaatc agtacgttca ttagccaaac gaatgttgtc agccacttcc tgtgctgctc
    11881 cttcaccttg aactttggtt ggaaaaagta aaatatctac accgggaaaa cgacgcgaga
    11941 ctgttgtgat aatatctcta ataaccgctc cactaggact ggtgacaaca ccaatctttt
    12001 taacaaactg cgacagtctt tgtttatgcc tatcgtcaaa ataaccagcc tcagccagtt
    12061 ttttcttaag ttgttcaaac tgaacagcca gtgcaccgat accatctggc tctgcctttt
    12121 caatgatgat ggaataagaa ccactaggtt catacagttg cacacgacca ataacattga
    12181 ttttcatgcc ttcttcgagc tcaaagccca atttcctata aataccgctc cacatggtcg
    12241 cctgaatgac agctttctca tctttaaggg agaaatactg atgattggga cgtcttctga
    12301 aattagaaac ctgacctgtc agataaactc gttccaaata aggatcgcga tcaaatttta
    12361 attttaaata tttggttaaa gaggatactg ataaataatc tgacataaat ctcatctaaa
    12421 gaccaaagac aaaggaaaaa ggtattcttg gaatcctgtt ccaaagtcta aaacaaatga
    12481 ccgtttttct tgatctttcg cctgtcttta tcttggctcc ttttccgtta atatagctgt
    12541 tattattata ccaaaaaatg aaaatttata cttccttttg aaatagaaaa atgagagcag
    12601 cagttcattt atctcctcat aagaatggag aatgacagaa aaatataaat tgatgatata
    12661 tacaacctaa ccttttcatg gcaatctaac cagtaacttt taaaaataag caagcttgaa
    12721 aatctaaaat aaaacgttta caatagaaaa ctagaaacag acgtcatcaa aaaagtattt
    12781 cgaaaaagag ttttttttgc taataagtaa ctgtccgtat tagatttcaa taataggaga
    12841 agcgcaatat gttaatgata ttattatttc agagacttgg tattatcatg attctggcat
    12901 ttttactagt caataacagc tattttcgac agttgattga agaacgttct aagcgtgaaa
    12961 agctggttct tattatcatt tttggtattt tcgtcatcat ttccaatatg acaggaattg
    13021 aaatcactag cgataaaagt ttggtggaac gtcctattct aacgactatt tctcattcag
    13081 attctctagc taatacgaga actttggtta tcacaacggc tagcttagtc ggcggtcctt
    13141 tagttggaac tgttgtgggt ttcattggtg gtgtccatcg tttctttcaa gggaattttt
    13201 ctggtgcttt ttacattgtc agttctgctt tggtaggata tattagtggt cgactgggtg
    13261 atcaattaaa aactaataac ctttatccat ctacttcgca ggtcattgtt atcagcatta
    13321 ttgctgaaag tattcaaatg ctctttgtcg gtttctttac tggctgggat ttggttaaac
    13381 tgattttcat tcctatgatg ttgcttaaca gtctaggttc gaccttattt ctagctattc
    13441 tcaagaccta cttatccaat gaaagacagc tgagagctgt tcagactcgg gatgttttag
    13501 atttgacgca gcaaaccctg ccttatttaa gacagggact gagtcagcaa tcagctacta
    13561 aagtgtgtaa tatcattaag cagcatacta attttgatgc cgttggtctg actgatcgaa
    13621 ccaatgtcct agctcatatc ggcgttggtc aagatcatca tattgccgga caagcggtca
    13681 aaacagatct ctcaaaaagt gttattttaa acggtcagcc acaaattgcc ttagataaaa
    13741 cagccattgc ctgtccagac caaagctgtc tcctcaattc agccatcgtc gttccgctca
    13801 agatcaataa tgagacagtt ggggccttaa aaatgtactt ttctggtgat aagaagatga
    13861 ccgaagtcga agaaaatctt gccctaggtc tcgcacaaat tttttctgga caattggcca
    13921 tcggtattgc cgaggaacaa aataagttgg ctaatattgc agaaatcaag gccttgcagt
    13981 cccagattaa tccccatttt ttcttcaatg ccataaacac catcagtgct ttgattcgtc
    14041 ttgatgccaa caaagctcga tatgctctca tgcaattaag tacttttttc cgaaccagtt
    14101 tacaaggcgg acaagataga gaaatcactt tagaacagga aaaagcgcac gttgatgctt
    14161 atatgaatct tgaaaagctg cgctttcctg ataaatatca actggattat catattactg
    14221 tttcaactaa aatgaccctg cctccttttg gtttgcaggt tttggttgaa aatgcggtgc
    14281 gtcatgcttt taaagaacgc aagaaagaca atcatatttg catttccata acagatcagg
    14341 gagagtttta caaggtggcc gttagcgata atggtcaggg tatttctcct aatatgattg
    14401 acaaattagg acaggaaact gtatctgaaa gcaagggaac aggaacagcc cttgttaatt
    14461 taaacaatcg cctaaattta ctttatggca gtgctagtca gttacacttt gacagtacag
    14521 atcaaggaac aaccgtctgg tatgagattc cttatcaaaa aggagataaa gatgaacatt
    14581 ttaattcttg acgatgaaat gttggcaaga caagagttaa cttttttaat tcagcagagt
    14641 aaggaacttg atcatcctga tatttttgaa gctgaagata ttagcagtgc tgaaaaaatt
    14701 ctctttcgcc agcagattga tttaattttt cttgatattt cactcagcga ggaaaatggt
    14761 tttaccttgg ccaatcaatt agagcaattg gcacatcctc cacttgtcgt ctttgcgaca
    14821 gcctatgatc attatgccgt taaagctttt gaaagcaatg ctgctgacta tattttgaag
    14881 cctttcgagc aggatcgtgt ggataaagct ttggctaaag ttaagaaaat acaacactta
    14941 tctacaatag atgagacagc cacgacagaa aagaaaggta tggaactgtt aacactgact
    15001 ttagcagata gaagcattgt ccttaagatg ccagacattg tggccgctag cattgaagat
    15061 ggggaactga ctgtcagtac caaaaacact agttatacca tcaagaaaac attaaattgg
    15121 tttaaaactc gcgccaagac caattatttt ctgcagattc accgcaatac ggttgttaat
    15181 ctggaaatga ttcaggaaat tcagccttgg tttaaccata cgctcttact ggtgatggtc
    15241 aacggtgaaa aattcccagt cgggcgttcc tatatgaaag aattgaatgc tcatttgacc
    15301 ttataaatga actagtttca ttaactcctc aaaattttca tttgacaatt ttacattggc
    15361 gttaagaagt tggatattgc aattcagctt cttttttttg caatcgggga cagttttgaa
    15421 aacgttttac acaaaatgag ctacaataac attgtcaaga aaggaaggag tcgttcgtat
    15481 tatgaaacac actagtaaag taacacaatc aaaatcagca cctatgttta ttcaaatgtc
    15541 tatctatgct gctattctgc tcgtttctca gcttatttca gaattattgc ctaaagcctt
    15601 accgattcca accaccgtta ttggtttaat tctcatgtat gtcctcttgt gcagccatat
    15661 tatcaaaatt gaatgggttg attccttggg ttccttatta attagtatga ttggctttat
    15721 gtttgtccca tcaggtattt ccctagcagc caatttaaat attctcaaag ctgaaggatt
    15781 gcagttggtc gctgttatta gcctatcgac cattctcatg ctagtcattg tcacctatat
    15841 cacttctatc attctgtcca tcaaaaaggt gaatgtggca agtctgtggg aaaaatggac
    15901 tgctcatagc tttgaaaaga aatttagcaa gaaagtagag ggaaaataag atggcactgt
    15961 taaaatcacc tatttttggt atttgttttt cattaatcct ttatacgatc gggcaagatt
    16021 tattcaaaaa gagtaaaggc ttctttctct tacaacccct tttctttgct atggttgcag
    16081 gcattatcgt acttgtttta ttggcaaaag gattgggaac tgatgttaaa accttatata
    16141 ctcaagctta taaacccggc ggagatttga ttttctggtt ccttaatccc gcaaccattg
    16201 cctttgccgt tccactttat aagaaaaatg acgctgtcaa aaaatattgg aaggaaatca
    16261 tcagcagttt gattatcggt atggtcgttt ccttagtcat cattgttgct atttcaaaag
    16321 ctattggttt aagccaagct agcactgctt ctatgctgcc gcaggcagca acaacagcca
    16381 ttgccctccc tattgctcac gctatcggcg gcaatactgc catcactgcc atggcttgta
    16441 tcctaaacgc cgttatcatc tatgctttag gcaaaaaatt agttgctttc ttccacctca
    16501 ataagagtga aatcggtgtt ggcttaggtt taggaacatc tggtcataca gttggtgcag
    16561 cctttgctct agaattagga gaactacaag gtgccatggc tgccatcgca gttgttgtca
    16621 tcggcctcgt cgttgacttg gttattccta tctttagcta catgatagga ttagtgcact
    16681 aaaaattaaa actgctatcg ataagacaaa agcctctcac ggatggttcc gcgaaaggct
    16741 ttttaaaagt aggggtatga aaggaaaaca aaaaaattca tttaattaat aaaattctac
    16801 ctcacataat tgtcaattaa gcttataaat cgtattcagc aaagacctct ttagcatcta
    16861 tcatattacc atctaaaata tcttgatatc ctttgtctaa tttagctttt aagcttgata
    16921 gattacttct tgttctgaag atttaatagg tgaggaaagg caattcatca aatttaaaaa
    16981 tatcgtttaa tactattttc gtcatatcac tcactcatct ccttcatcac tcttgttatc
    17041 tccgcactga ttctggttgg taggacgacg taggcctctt tgctcaattg gtctgctatg
    17101 taggagtgga ggaaaacagc ggctgcggca acctcaaagc ggtctgtgtg aaattgagca
    17161 acaaagcctg caatcattcc agccaaggta tctcccatac cgccagtcgc ttgataggga
    17221 ccgccaactt ggatatgtcc gattttttgt ccttgataaa tcttggtctg atgggatttt
    17281 gcgactagga tggtttcttt tggaaaatga gctagtgctg tttgtgttgc tgcttctatc
    17341 tgttctggaa tagtcagtcc agacaatctt tcccattctt tttgatgagg tgttaggatt
    17401 atttgcttgg ttggccaaat agctggtttt cttttggcta atagatttat agcagagcca
    17461 tcaataatca ggatctgttt tggtttgata gcctgccaaa ccacatcaaa ggttgtttga
    17521 gccaagtcat cttctgccaa gcccggtccc ataagaacca catctgctgc tgttatttgc
    17581 tctgacaaac gatctttttc aaccatatca aaagccatag cttcgggtaa atggctgtgc
    17641 agagctgtga tattgtcctt atgggtcgca accgtcacca aaccagctcc gctattgaca
    17701 caagcaaggg cagccatgat gatagcacca ccgtaagggt agttgccgcc aatcaaaagg
    17761 acacggccaa aagtcccctt gtgactgtta agaggacgtg gtttaattat ttttttcgtt
    17821 aaaagatcat caataatcat ttggtcacac ttcttaaagc tgcttgatag gtttgttcca
    17881 aaagcatggt gatggtcata ggaccgacac cacccggaac aggagtaatg aggctggctt
    17941 tttgagcgac gtggtcaaag ttaacatcgc cgataagttt tccatttttg tcacggttca
    18001 tgccaacatc aatgacaaca gcaccttctt tgacaaattc ctcagtgaca aaatttcctt
    18061 gaccaatagc aacaataagc acatccgcac agcgtgtgac ttctgataaa tgtttcgttc
    18121 tagaatgggt cagggtaact gttgcatttt tttcgagcaa taactgcgcc attggcttcc
    18181 caacgatatt ggaacgacca ataataactg catgcttccc ttcaagatca acgtgatagg
    18241 cactcagcat ttccataata ccagcggggg tacaaggtac catcatggaa cgaccgctcc
    18301 acaaatgacc agtattcata ggatgaaagc catctacatc cttatgagga tcaatggcta
    18361 aaatgatttt cttatcatta atgtgagccg gcagcggcaa ttgaaccaga ataccatgga
    18421 aggaaggatc ttgattataa ccttcaataa tctcaattaa ttcttcttca ctaatagagt
    18481 cagataggcg tatggtttca cttttaaatc ccgccttgat agctgagcgc tctttattac
    18541 gcacatagac ttgactggca ggattatcac ctactaaaat caccacaaga ccgggaacaa
    18601 gcccatgttt ttctttcatc tgttcaactt tattggctaa atgcaactgc agcttttgtg
    18661 ccaaggcttt accatcaata atttctgtca ttctcatctc ctgaaaaaat actgctttta
    18721 ttataccaaa aaaggcgagc agataacacg ctgctacacc tttttttcta tatttaaata
    18781 ttataatcag ttcaaaatat gaagctttgt cttaatgtgt cttgcttgat tttttcatct
    18841 catctttaac agggcaggca cagtcacaat cgccacaaga acctttctgc ttaatataat
    18901 gacggattcc taagaaagct ccagctgcaa ttaagatagc aataataaag gttgacatag
    18961 tcattcttcc tttctattag ttatgactta aacttaaatt atctaaggta atcacttttt
    19021 ctttgacctg acgtggtttt ctagcaataa agtaaagcat cacaagcaat aaaacaagag
    19081 ctaaacctgt ccaaagcgtc actggcttgc cataaaaagc gactaaacca agctggtaaa
    19141 taattaagct aacaagataa gccagacccg tttgataagc aatagccact aaagtccact
    19201 tcagatttcc catttcgcgt ttgatagctc cgattgaggc aaaacaaggc gcacaaagca
    19261 aattgaaggt caaaaatgaa taggctgcca aagctgtata atccccctga aggctaaccc
    19321 atagtgaatg cgttgtttct gttgcatcgg gattattgta gagaattcca aaagttgcaa
    19381 ctactgtttc cttagctgca agaccggtta gagcagcaac agtcgccttc caatttccaa
    19441 aaccaagcgg tgtaaagatc caagccaaga gacgaccaag actagccaaa atactgtttt
    19501 ccgtatcaac tgaatgcaaa gtaaaattat aggaactcat aaaccagatt aaaacggtta
    19561 aactaaagat aatcgttcca gcacgcttaa caaaactcat agccttacca aaagcatagc
    19621 gcaaaacagc atcaaccttt ggtagatgat aacttggtaa ttccatgata aaaggactcg
    19681 tataaccgcc taaaaaacta gttttcttaa gggcaatacc tgataaaata atagcaatca
    19741 ttcccatgaa ataagcactt ggagctatcc aaggattatg agggaaaaag gctcccgcaa
    19801 ttaaggcaat gacggacagc ttagctgaac aaggcataaa agtcgttgtc ataatggtaa
    19861 tacggcgatc acgttcattc tcaatggttc gactggccat aattcccgga acaccacacc
    19921 ccgttgaaat aagcatagga ataaaggatt ttcctgaaag tccgaaacgt ctgaaaatcc
    19981 gatccataac aaaagcaatt cgactcatat aaccaatatc ttctagaatt cccagacaga
    20041 taaagaggac aaaaatttgc ggtaaaaagc caagaactgt cccaacacca gcaacaaccc
    20101 catcaataat caacgattgt agccaagcct gcactttcaa tgcctctaaa acacctgtga
    20161 caaattcagg tacgtattta ccaaaaagaa tatcattaac ccaatccgtc cccattgttc
    20221 ccaccgtttg aatggacaag taataaacta agaacataac gaccgcaaaa atgggcagag
    20281 ccaaaacgcg attagtcaca attttatcaa ttttatcaga agcagacatc ttaaaatcat
    20341 tatcttgact ttgtgccatt tggctcacac gttcaatgaa agcataacgc tgattaatca
    20401 cgatggactc tgaatcttct gtgaagactt cctcggtgat ttgaatgatg tctttaattt
    20461 ccttcttttg aaagggagat aaatctaatt cctcttcaac caaacggtcg cgctcaaata
    20521 atttgatggc ataaaaacgg ctagaacgtt ctggtactgt ctgaccgaga acctcaataa
    20581 tttgggcaat cgctgcttca aatttggcat cgtaagttgg gtattgaata ctatcaacac
    20641 tgcccttagt tgtttgactg gcttttttaa cagccttgtc aacgcctgta tttttcaaag
    20701 cactggtcgc aacaactggc actcccatct gataagccaa tttatcacta ttaatagatt
    20761 ttccttgatt ttttaacaca tcgctcatat taagcgcaat cgttacagga attcctgtct
    20821 caattaactg cgtcgttagg taaaggttgc gttccagatt cgtggcatca
//
