LOCUS       NZ_PVZV01000007        24795 bp    DNA     linear   CON 13-DEC-2024
DEFINITION  Actinocorallia populi strain A251 contig7, whole genome shotgun
            sequence.
ACCESSION   NZ_PVZV01000007
VERSION     NZ_PVZV01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinocorallia populi
  ORGANISM  Actinocorallia populi
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Thermomonosporaceae; Actinocorallia.
REFERENCE   1  (bases 1 to 569948)
  AUTHORS   Li,X.
  TITLE     Actinocorallia populi sp. nov., an endophytic actinomycete isolated
            from a root of Populus adenopoda (Maxim.)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 569948)
  AUTHORS   Li,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) College of Light Industry, Textile and Food
            Engineering, Sichuan University, No. 24, First South Section First
            Ring Road, Chengdu, Sichuan 610065, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR MAR-2018
            Expected Final Version            :: yes
            Genome Coverage                   :: 221.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002995495.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 14:18:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,861
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,716
            CDSs (with protein)               :: 7,716
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 18 of 83
            Pseudo Genes (incomplete)         :: 70 of 83
            Pseudo Genes (internal stop)      :: 6 of 83
            Pseudo Genes (multiple problems)  :: 10 of 83
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:05:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 285918
            Orig. end                         :: 310713
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVZV01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24795
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..24795
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24795
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:14795](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14795
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            complement(10..384)
                     /locus_tag="C2865_RS28085"
     CDS             complement(10..384)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547500.1"
                     /locus_tag="C2865_RS28085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YchJ family protein"
                     /protein_id="WP_106401598.1"
                     /transl_table=11
                     /translation="MSSKCPCGLSEPYERCCGRFHAGESSAPTAEALMRSRYSAFSVGD
                     SDYLRRTWHPATRPAGTGVDRRTRWTGLEVLETARGGPFDTEGTVRFRAHYVERGRRGR
                     MEENSKFVRVEGDWVYVGTV"
     gene            complement(455..835)
                     /locus_tag="C2865_RS28090"
     CDS             complement(455..835)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019633618.1"
                     /locus_tag="C2865_RS28090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="signal peptidase I"
                     /protein_id="WP_106401599.1"
                     /transl_table=11
                     /translation="MTDDIYVGNANIDAPEERGWLLGHFMPEGDARHSTDVEIKWGVHP
                     PGDTRAAWVHGEHRTALLVLISGRFRMEFPGRDVVLSKQGDYVVWGRGVDHSWYAEEES
                     VVLTVRWPSIPGYKVEGAETGP"
     gene            complement(895..1611)
                     /locus_tag="C2865_RS28095"
     CDS             complement(895..1611)
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888782.1"
                     /locus_tag="C2865_RS28095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="WP_106401600.1"
                     /transl_table=11
                     /translation="MGTEKPGSLWERLERPAPAPRQTLSPERIASTAVALADAEGLEAV
                     TMRRLAAELGVAPMAPYRYLSGKDDLLDLMVDHVYAEPWTPDGLGWREALRDLAFRTRE
                     LTLAHPWLGRLPLRAKLALTPNRMAVAEQALAVLDGHDMDADTMMSVFRAVDAYVEGAT
                     GYETAVTELIDDEGLAGGDGLRSELAPTMVWLTGTGRYPAFEKYLRTATRKDDAEWRFA
                     HGLDCLLEGIAARLGI"
     gene            1700..2287
                     /locus_tag="C2865_RS28100"
     CDS             1700..2287
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888781.1"
                     /locus_tag="C2865_RS28100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="WP_106401601.1"
                     /transl_table=11
                     /translation="MHEMKIAILVGSTRDGRFAPSVAAWTESLIAERGDMRADVIDLVE
                     TPLPTVFPVLGQPPASAADRELLAAVSPRLAEADAFVIVTPEYNHSFPAALKNAIDWHN
                     TEWHAKPVAFVSYGAFSGGLRAIEQLRPVLAEVHAVAIRDAVSLQSPWEQFDGDGRAVD
                     PAVEAAGRLMLDRLAWWTHALRTARAATPYAA"
     misc_feature    1708..1723
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.96"
                     /tool="antismash"
     gene            2289..3833
                     /locus_tag="C2865_RS28105"
     CDS             2289..3833
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888780.1"
                     /locus_tag="C2865_RS28105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MDR family MFS transporter"
                     /protein_id="WP_106401602.1"
                     /transl_table=11
                     /translation="MDDLARTERRSLHAGVFGLLLGMFLAMLDGLVVGTALPTIAGDLG
                     GLDRLPWVVTAYMLAAAATTPVWGKLGDLFGRKAVFVTAIVLFLAGSVLCGLARDMAQL
                     IGFRAVQGLGAGGLMVGALAVIGVLVPPRDSGRIQSMIGVIMPIAYVGGPLLGGLLTDH
                     LSWRWTFYVNVPVGAVALLLIATRVHPPPAPRGRPRIDYAGAALLTASIVALTLLASWA
                     GTAYPWASPQILGLGAAGVLGVAWFVAVERRAAEPIIPPRLFADRDFTVVQVLGFLVGA
                     AMLTVTNYLPQYFQFVQGASPAAAGMLLLPLMFGMLGAQLLTGRLISADGRYRRYPILG
                     GALMTAGVLALLQLGTGTPAPAASALTFLIGAGIGLLMQSSTLITMNSADPRDMGAANG
                     TLMLFRTIGGSLGIALLGTLYAARMAADLTARLGPSTAAHLTEGGALTPALLPALPAET
                     VDAVRSAVTGGLHLILYGTLVLALLTFAASWLIREVPLRTALPPSTPEPHRSPADR"
     gene            complement(3961..5751)
                     /gene="glsA"
                     /locus_tag="C2865_RS28110"
     CDS             complement(3961..5751)
                     /EC_number="3.5.1.2"
                     /GO_function="GO:0004359 - glutaminase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glsA"
                     /inference="COORDINATES: protein motif:HMM:TIGR03814.1"
                     /locus_tag="C2865_RS28110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutaminase A"
                     /protein_id="WP_198653661.1"
                     /transl_table=11
                     /translation="MNAPFVSPIQDLLDDLHARLIEQRAGEVATYIPELGKADPEWFGL
                     AVATLDGTVYEAGDSRVPFTIQSVSKPFVYALALQDRGLPDVLKQVGVEPTGDAFNAVR
                     LEPYTGRPYNPMVNSGAIVTSTLVGGDTFEERRERILTGLSAFAGRELAVDRKVMDSEA
                     ATGDRNRALAYLMHGAGTLTCDVEESLRLYFEQCAALVTTSDLAVMTATLAGGGINPLT
                     GETVVSVEAAANALTVMATCGTYDYAGEWLVRAGLPAKSGVSGGLIAALPSQLGLGLFS
                     PRLDSRGNSVRGVAACEELSQRFGLHLMRPAERSGPVFHRTLRGDTAHSSRVRAHDERT
                     ALARLGGAIRVYVLRGDLAFSSAEAVVRTISEDTGSVRWVVLDLKRAGRVASVAETLME
                     GLAAKLKERGITTVVVDTEKGVTVPSAVISETRDAALEWCEDALLESAGASRMTVPLAE
                     QDLLRSLDPFLVTALEAYLEPREYAPGERLLEDVAALCFIISGGLARQIMVGTPPRPVR
                     ETSMGPGTAVGRLALIDDAEHTHRIVAECPTSCLVLTTRELARLERDSPRLADALRWSI
                     ANAIAARLRRTDAENHALIH"
     gene            complement(5774..6370)
                     /locus_tag="C2865_RS28115"
     CDS             complement(5774..6370)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657842.1"
                     /locus_tag="C2865_RS28115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_106401603.1"
                     /transl_table=11
                     /translation="MEIDTRARRAQILAAAAELFARRGYHGVSIGELGASVGLTGPALY
                     RHFAGKEALLAEILLDISARLHDEGFRRAAAAADPLGALLDWHISFALDHPALIVVHER
                     ELENVPEAPRREIRRLQRAYVEEWVRVTREQWPRPEDEARAAVHAVFGLLNSTPHSAGE
                     LDRAGMARLLRRMAEAALLAGTAACPDTDTGDLRE"
     misc_feature    6392..6405
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.77"
                     /tool="antismash"
     misc_feature    complement(6392..6407)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.07"
                     /tool="antismash"
     misc_feature    complement(6394..6407)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.77"
                     /tool="antismash"
     misc_feature    6395..6408
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.74"
                     /tool="antismash"
     misc_feature    6395..6410
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.97"
                     /tool="antismash"
     misc_feature    complement(6398..6413)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.62"
                     /tool="antismash"
     misc_feature    6403..6417
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.75"
                     /tool="antismash"
     gene            6430..8061
                     /locus_tag="C2865_RS28120"
     CDS             6430..8061
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017598003.1"
                     /locus_tag="C2865_RS28120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_106401604.1"
                     /transl_table=11
                     /translation="MGAAAARPRRPYRPDRAIRWRRDTLGVLPSRADAAGEPYKRNAEA
                     NAELAAQLRERLAATALGGSARARERHVSRGKLLPRERVDRLLDPGSPFLELSPLAAWG
                     LYDGQAPGAGMITGVGRVSGRECVVIANDATVKGGTYFPMTVKKHLRAQEVALHNRLPS
                     IALVDSGGAFLPMQDEVFPDREHFGRIFYNQANLSALGVAQLAAVMGSCTAGGAYVPAM
                     SDENVIVRNQGTIFLGGPPLVKAATGEVVTAEELGGGDVHSRVSGVTDHLAEDDADALR
                     ILREIVATLGPRPPRPWDVRPSAEPLYDPSELYGIVPADPRTPYDVREVVARVVDGSEF
                     TEFKKEYGPTLVTGFARIQGHPVGIIANNGILFAESAMKGAHFIELCDRRSIPLVFLQN
                     ITGFMVGRDYEHGGIAKHGAKMVTAVSCARVPKFTVIIGGSYGAGNYAMCGRAYSPRFL
                     WMWPNARISVMGGEQAASVLTTVGDADADAVREQYETQGEPYYSTARLWDDGVIDPVDT
                     RRVLGLALSAAANAPLADVGYGVFRM"
     gene            8067..10004
                     /locus_tag="C2865_RS28125"
     CDS             8067..10004
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852327.1"
                     /locus_tag="C2865_RS28125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="biotin carboxylase N-terminal domain-containing
                     protein"
                     /protein_id="WP_198653662.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2.2e-07, bitscore:
                     26.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.6e-10,
                     bitscore: 34.7, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 3e-09, bitscore: 31.7,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTTVLIANRGEIAVRVQRTLRRLGVRSVAVYAPDDAGSVHVREA
                     DEAVRIPSYLDGAAIIEAARATSAQAVHPGYGFLAENAAFARACAEAGVVFIGPPPSAI
                     DAMGDKIEAKLTVAAAGVPVVPGRDERGLSDEQIAEAALEIGLPVLLKPSAGGGGKGMR
                     LVRAEEELAGAIASARREARGAFGDDTLLAERFIDGPRHIEVQVFADAHGNVVHLGERE
                     CSLQRRHQKIVEEAPSPLLDAAQRAEIGAHAVNAARSIGYVGAGTVEFIVAGERPDERY
                     FMEMNTRLQVEHPVTELVTGLDLVELQLRVASGEPLPFTQDDVVLTGHAVEARVYAEDP
                     ARGFLPTGGRVLALAEPAQARVDSGIGAGDEIGSRYDPMIAKVVVHGRDRAEALRALDR
                     ALAEYSLLGVHTNVAFLRRLLARPEVVSGELDTGLVERVLPELNAGDATVPEWVLAAAA
                     LERMRADAPAGDGPWDAMDGWRVGEAAWTPHALVVDGGEPVEARTRGEEVAVGDGPPRH
                     AVLSGEALVLDGRRHPHRRATGHDGAVWIGADGRTWSVRERERLAAGGASAVAGGVLRS
                     PMPGTVLAVKVAEGDAVAEGQPVVIVEAMKMEHTVVAAVAGTVARLPVRVGDQVALDAV
                     LAEITSEEAE"
     gene            10001..10891
                     /locus_tag="C2865_RS28130"
     CDS             10001..10891
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009072755.1"
                     /locus_tag="C2865_RS28130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_106401606.1"
                     /sec_met_domain="HMGL-like (E-value: 8.6e-46, bitscore:
                     151.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLPEQVTIYEVGPRDGLQNEKTAIPVEVKAEFIGRLADAGLKTI
                     EATSFVHPKWVPQLADADELLKRMDRRPGVSYPVLVPNERGMGRALAAGVGEIAIFASA
                     TESFAQRNLNRSMDEQYAMFEPVVSRALAEGMRVRVYLSMAFGDPWEGDVPVPQVVAAG
                     KRLLEMGCYQLSLGDTIGVGTAGHVQELIAAFGDPAALAVHFHDTYGQALANTLAALQS
                     GVTTVDASAGGLGGCPYAESATGNLATEDLVWMLDGLGIRHGVSLDSLVETSTWMAGRL
                     GRPSPSRVVTARSNS"
     gene            10888..12030
                     /locus_tag="C2865_RS28135"
     CDS             10888..12030
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852325.1"
                     /locus_tag="C2865_RS28135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_106401607.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.6e-39, bitscore:
                     128.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.6e-22, bitscore:
                     72.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.9e-48, bitscore:
                     158.5, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDFTLTEEQEALRQSVEAFAREAVSPVIGGHYERGEFPYELVAG
                     MGKMGLFGLPFPEEYGGMGGDYFALCLALEELARVDSSVAITLEAGVGLGAMPIYRFGT
                     EEQKRRYLPKLLTGERLAGFGLTEPGGGSDVPGGMRTTARLEDGQWVVNGSKCFITNSG
                     TDITEFVTVTALTGENEISTIIVPNGTPGFTVGPEYSKVGWRASDTRELFFDDVRVPEE
                     NLVGPRGRGYAQFLRILDEGRIAIAALSVGLAQGCVDESLRYVKERQAFGRAIGEYQAI
                     QFKIADMEQRVWTARVAYYAAAARMLRGEPFKKEAAIAKLTASNAAMDNSRDATQIFGG
                     YGFMNEFPVGRFYRDAKILEIGEGTSEVQRMIISRQLGLA"
     gene            12027..12794
                     /locus_tag="C2865_RS28140"
     CDS             12027..12794
                     /NRPS_PKS="Domain: ECH (5-247). E-value: 7.7e-56. Score:
                     181.1. Matches aSDomain:
                     nrpspksdomains_C2865_RS28140_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981928.1"
                     /locus_tag="C2865_RS28140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_106401608.1"
                     /transl_table=11
                     /translation="MITLNRHGHVAEIVLDRPKAHNALSTEMAVRLASVCAEVADSDAR
                     AVVLSSSAEKSFCVGADLKERASMTDDDLMRQRPVFRRAFGAVLHLPQPVVAAVHGFAL
                     GGGTEFALSCDLVVADPTAVFGLPEVGVGLIPAGGGTQLLQRRVGTAKAADLIFTGRKV
                     GFDEAVALGLVDRPAPAGEDRAAALELAGTIAANSPVALRAAKRALRHGAPLDLAAALD
                     VEDAAWRTAALSGDRREGIAAFNEKRRPEWPGL"
     aSDomain        12042..12767
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2865_RS28140_ECH.1"
                     /evalue="7.70E-56"
                     /label="C2865_RS28140_ECH.1"
                     /locus_tag="C2865_RS28140"
                     /protein_end="247"
                     /protein_start="5"
                     /score="181.1"
                     /tool="antismash"
                     /translation="RHGHVAEIVLDRPKAHNALSTEMAVRLASVCAEVADSDARAVVLS
                     SSAEKSFCVGADLKERASMTDDDLMRQRPVFRRAFGAVLHLPQPVVAAVHGFALGGGTE
                     FALSCDLVVADPTAVFGLPEVGVGLIPAGGGTQLLQRRVGTAKAADLIFTGRKVGFDEA
                     VALGLVDRPAPAGEDRAAALELAGTIAANSPVALRAAKRALRHGAPLDLAAALDVEDAA
                     WRTAALSGDRREGIAAFNEK"
     gene            12861..14795
                     /locus_tag="C2865_RS28145"
     CDS             12861..14795
                     /EC_number="6.2.1.16"
                     /GO_function="GO:0030729 - acetoacetate-CoA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (93-518). E-value: 3e-59.
                     Score: 192.5. Matches aSDomain:
                     nrpspksdomains_C2865_RS28145_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009085960.1"
                     /locus_tag="C2865_RS28145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetoacetate--CoA ligase"
                     /protein_id="WP_106401609.1"
                     /sec_met_domain="AMP-binding (E-value: 5.6e-57, bitscore:
                     188.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQEGITLWEPSQETVERARITAFMRALPSRPRDYDELWRWSVADV
                     DGFWQTVWDHFQIVGDRGDGPVREGGPTPVDGLRWFPSARLNYAENMLRHAAERPDRTA
                     VVYRTDDGTTVELTWARLAEQVAGARAGLAALGVGRGDRVAGYLPNRPEALVVMLAAAS
                     LGAAWSSCSPDFGAPSVIDRFQQIEPKVLLAVDGYVYNGRVFDRRETLAEIRAALPTLA
                     ATVLIDVVPGEPVAGALPYDELARPAEPAFDRVPFDQPLWILYSSGTTGLPKPIVHGHG
                     GMVLEHVKSLALHQDLGPDDVFLWFTTTGWMMWNYLVSGLMLGATIVLFDGAPAGEVLW
                     RLAAETGTTHLGLGAPYIMASRKAGLTPGASLDLSALRLIGSTGSPLPPEGFSWVYEEV
                     KRDVLLGSLSGGTDVCSGFVGPVPLLPVRAGVIQCRALGAKIEAFDEAGRPVVDEVGEL
                     VLTEPMPCMPVGFWNDPGNVRYREAYFEDFPGVWRHGDWVKVLPDGGCVIYGRSDSTLN
                     RGGIRMGTSDFYRVVESFEEIADSLVIDTGGLGAEGELILYVQLAPGAELGEELLGRLR
                     AALRADLSPRHVPDRFVPVPGVPRTLSGKKLEVPVRKILQGVDPDKAVNRGSLADPSVL
                     DHYVPDASA"
     aSDomain        13140..14414
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2865_RS28145_AMP-binding.1"
                     /evalue="3.00E-59"
                     /label="C2865_RS28145_AMP-binding.1"
                     /locus_tag="C2865_RS28145"
                     /protein_end="518"
                     /protein_start="93"
                     /score="192.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RHAAERPDRTAVVYRTDDGTTVELTWARLAEQVAGARAGLAALGV
                     GRGDRVAGYLPNRPEALVVMLAAASLGAAWSSCSPDFGAPSVIDRFQQIEPKVLLAVDG
                     YVYNGRVFDRRETLAEIRAALPTLAATVLIDVVPGEPVAGALPYDELARPAEPAFDRVP
                     FDQPLWILYSSGTTGLPKPIVHGHGGMVLEHVKSLALHQDLGPDDVFLWFTTTGWMMWN
                     YLVSGLMLGATIVLFDGAPAGEVLWRLAAETGTTHLGLGAPYIMASRKAGLTPGASLDL
                     SALRLIGSTGSPLPPEGFSWVYEEVKRDVLLGSLSGGTDVCSGFVGPVPLLPVRAGVIQ
                     CRALGAKIEAFDEAGRPVVDEVGELVLTEPMPCMPVGFWNDPGNVRYREAYFEDFPGVW
                     RHGDWVKVLPDGGCVIYGRSDSTLNR"
     CDS_motif       13647..13700
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2865_RS28145_0001"
                     /evalue="7.00E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="C2865_RS28145"
                     /protein_end="280"
                     /protein_start="262"
                     /score="12.6"
                     /tool="antismash"
                     /translation="ILYSSGTTGLPKPIVHGH"
     gene            14844..17018
                     /locus_tag="C2865_RS28150"
     CDS             14844..17018
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014790.5"
                     /locus_tag="C2865_RS28150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_106401610.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.1e-22, bitscore:
                     76.0, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.1e-22, bitscore:
                     75.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 7.8e-17, bitscore:
                     56.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTERDSAEGLRELRNEVRSFVREWQEEGRFAPRCDSWLREHDTA
                     FSRALAGRGWIGLTWPREYGGAERSHLARLVVTEELLRAGAPVAAHWMADRQIGPAILR
                     HGSAGLKRRFLPGITRGEITFCVAMSETEAGSDLAAVRTTAARTGEGWLLNGRKVWTSH
                     AHRSTHAYVLARTDATGRKHEGLSEFLLDLATPGVTVRPLFDLSGEHHFNEVFFDDVLI
                     PHDRLLGVEGQGWKQVTEQLSFERGGAERVLSTYPLLAAFVADVDPGDSLAVQAAGELT
                     ARLSVLRAMAWRVAADMDEGRAPIREAALLKSLGTAFEKDVVETVRRVRGALPDPDGGG
                     LERLMAQAVPAVPGFSLRGGTTEILGTIVAKGLTSDAPSRPGRTPLGELAADVLAGRGQ
                     DPGLWEELRELGWAGAGLPEELGGEGGTLTELLTLLEAVGEHGAAVPLLETSLACRLLV
                     RAGRPLPARMTATVALPGPGLRTGETLDGTIERVPWASAADLVVVPLDGELVLLDGTVP
                     GWRVEPGRNLAGEPRDTVHLDGCRIPPGHRIACDVSREEVVERAALLQGAQLVGALRTA
                     LRLAADHARTREQFGRPLAAFQAVSLTLAGAAARVEGAETALARAAEAGTGAPVAALRL
                     WLAEAAGEVAAAAHQVHGAMGVTREHPLHHTTRRLWAWRDEWADARHWAGALARAAGPG
                     PGDDRLWGSTGVDVQVAVQADVQDDRGGRA"
     gene            17015..17782
                     /locus_tag="C2865_RS28155"
     CDS             17015..17782
                     /EC_number="4.2.1.17"
                     /NRPS_PKS="Domain: ECH (12-246). E-value: 5.4e-45. Score:
                     145.5. Matches aSDomain:
                     nrpspksdomains_C2865_RS28155_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852842.1"
                     /locus_tag="C2865_RS28155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_106401611.1"
                     /transl_table=11
                     /translation="MSRWKTLRLESRDGGVRVLTLDDPARHNAISFAMRDDLVDCAARL
                     RADHDARVLIVTGAGRSFCSGADLGELFGAEDLPVREIRDDAARMYDAFLAVRDLPIPT
                     IAAVQGHAIGAGLNLAMSCDVRLAAPQAKFSATFSRIGLHPGGGCTYFLVEALGRQRAL
                     AVLLEGGTLAGEQAVRHGLALELHDDPLAAALEMAGRFASVPPGLARDIKTAVGLAATQ
                     GFEATLAFEAWAQADSSTRPATRETLNRTFRRP"
     aSDomain        17051..17752
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2865_RS28155_ECH.1"
                     /evalue="5.40E-45"
                     /label="C2865_RS28155_ECH.1"
                     /locus_tag="C2865_RS28155"
                     /protein_end="246"
                     /protein_start="12"
                     /score="145.5"
                     /tool="antismash"
                     /translation="DGGVRVLTLDDPARHNAISFAMRDDLVDCAARLRADHDARVLIVT
                     GAGRSFCSGADLGELFGAEDLPVREIRDDAARMYDAFLAVRDLPIPTIAAVQGHAIGAG
                     LNLAMSCDVRLAAPQAKFSATFSRIGLHPGGGCTYFLVEALGRQRALAVLLEGGTLAGE
                     QAVRHGLALELHDDPLAAALEMAGRFASVPPGLARDIKTAVGLAATQGFEATLAFEAWA
                     QADSSTRPATRE"
     gene            17843..18928
                     /locus_tag="C2865_RS28160"
     CDS             17843..18928
                     /EC_number="1.1.1.306"
                     /GO_function="GO:0050607 - mycothiol-dependent formaldehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0010127 - mycothiol-dependent
                     detoxification [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (25-256). E-value: 1.8e-10.
                     Score: 32.4. Matches aSDomain:
                     nrpspksdomains_C2865_RS28160_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017586196.1"
                     /locus_tag="C2865_RS28160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S-(hydroxymethyl)mycothiol dehydrogenase"
                     /protein_id="WP_106401612.1"
                     /sec_met_domain="ADH_N (E-value: 3.8e-28, bitscore: 92.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 9.7e-31, bitscore:
                     101.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQRVRGVVAPGRNEPVRVETIIIPDPGPGEAVVKVQACGVCHTD
                     LHYKQGGINDEFPFLLGHEAAGIVESVGDGVTEVAPGDFVVLNWRAVCGQCRACLRGRP
                     WYCFNTHNAKQKMTLEDGTELSPALGIGAFADKTLVAAGQCTKVDPAAKPEVAGLLGCG
                     VMAGIGAAINTGGVTRGDSVAVIGCGGVGGASIMGARLAGARRIIAVDIDQRKLDKALE
                     LGATHTVNSKETDAVEAIRELTGGFGADVVVEAVGRPETYEQAFYARDLAGTVVLVGVP
                     TPEMRLELPLLEVFGRGGALKSSWYGDCLPSRDFPMLIDLYLQGRLDLGAFVTETIGID
                     GIEAAFAKMHHGDVLRSVVIL"
     aSDomain        17918..18610
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2865_RS28160_PKS_ER.1"
                     /evalue="1.80E-10"
                     /label="C2865_RS28160_PKS_ER.1"
                     /locus_tag="C2865_RS28160"
                     /protein_end="256"
                     /protein_start="25"
                     /score="32.4"
                     /tool="antismash"
                     /translation="DPGPGEAVVKVQACGVCHTDLHYKQGGINDEFPFLLGHEAAGIVE
                     SVGDGVTEVAPGDFVVLNWRAVCGQCRACLRGRPWYCFNTHNAKQKMTLEDGTELSPAL
                     GIGAFADKTLVAAGQCTKVDPAAKPEVAGLLGCGVMAGIGAAINTGGVTRGDSVAVIGC
                     GGVGGASIMGARLAGARRIIAVDIDQRKLDKALELGATHTVNSKETDAVEAIRELTGGF
                     GADVVVEAV"
     CDS_motif       18023..18061
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2865_RS28160_0001"
                     /evalue="3.10E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="C2865_RS28160"
                     /protein_end="73"
                     /protein_start="60"
                     /score="10.6"
                     /tool="antismash"
                     /translation="LGHEAAGIVESVG"
     CDS_motif       18647..18679
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2865_RS28160_0002"
                     /evalue="1.00E+00"
                     /label="PKSI-ER_m2"
                     /locus_tag="C2865_RS28160"
                     /protein_end="279"
                     /protein_start="268"
                     /score="3.0"
                     /tool="antismash"
                     /translation="RDLAGTVVLVG"
     gene            18925..19554
                     /locus_tag="C2865_RS28165"
     CDS             18925..19554
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018656608.1"
                     /locus_tag="C2865_RS28165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_106401613.1"
                     /transl_table=11
                     /translation="MTAAISHLVTSGTFSLDGGIWDVDNNVWIIGDEHEAIVIDAAHDA
                     AAIRDALGGRTLKAIVSTHAHNDHIDAAPVLADATNAPILLHPADLPLWEMTHPDRRPD
                     GELADGQALTVGGIELKVLHTPGHAPGAVCLYAPELGTVFTGDTLFQGGPGATGRSFSD
                     FPTIIGSIREKLLTLPGDTKVYTGHGDSTRIGDEAPHLQEWLDRGH"
     gene            19617..20309
                     /locus_tag="C2865_RS28170"
     CDS             19617..20309
                     /EC_number="1.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013077.5"
                     /locus_tag="C2865_RS28170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitroreductase family protein"
                     /protein_id="WP_106401614.1"
                     /sec_met_domain="PF00881 (E-value: 9.3e-29, bitscore: 95.7,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELLEALRGTAAIREFTEEPVSDAVVHRILDTARFAPSGGNKQGW
                     RVVVVKDPEVRAKMRDLYLPGWRDYRALGEAGLRAWSPLADREAEAAALDREPAEDHRA
                     DFALNMDKVPVMLAVFADLNELAAVDRDHDRYTFAGGASVYPFVWNLLLAAREEGLGGV
                     MTTIHIRQEEGVRELLGAPDGVALASVVFLGHPVRRPTRLRRAAVSEFATFDSFDGSPV
                     TPPDVTDQ"
     gene            20321..20734
                     /locus_tag="C2865_RS28175"
     CDS             20321..20734
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653983.1"
                     /locus_tag="C2865_RS28175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioesterase family protein"
                     /protein_id="WP_106401615.1"
                     /sec_met_domain="4HBT_2 (E-value: 1.8e-14, bitscore: 49.3,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYLYWESVPTRWNDNDCYGHMNNVIHYEMMDTVANTWLIREAGF
                     DPFHGDTIGMCVASRCEYKAEARFPEVIRVGLRIGRLGTSSVRYEIGLHRADGETLIAH
                     GDFTHVFVDRETRRPVPITGRMREAMEKLVVAS"
     gene            20731..21846
                     /locus_tag="C2865_RS28180"
     CDS             20731..21846
                     /NRPS_PKS="Domain: PKS_ER (23-289). E-value: 8.5e-11.
                     Score: 33.5. Matches aSDomain:
                     nrpspksdomains_C2865_RS28180_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653982.1"
                     /locus_tag="C2865_RS28180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_106401616.1"
                     /sec_met_domain="ADH_N (E-value: 7.6e-26, bitscore: 85.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.2e-29, bitscore:
                     98.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTRVSVLTELGREAPYAASRPLEVTEVTLDPPGPGELLVRIGA
                     AGLCHSDLSVINGSRVRPLPMALGHEAAGEVVEAGEGAEFAVGDRVVLAFVPACGRCPR
                     CRSGRPALCVPGAAANGAGTLLGGGRRIDGGRINHHLGVSAFSDYAVVSQQSAVKVDSD
                     LPFEIAALFGCAVLTGAGAALHSAQVAPADSVAVFGLGGVGLSALLAAKALGAETIVAI
                     DVVPAKLELARELGATHTVAGGPDAVAELKEITGGGADKVIETAGVVPVLRQAYDAAAP
                     GGTTVTVGLPAPGRELALPALSLVAEEKTLRGSYLGSCAPRRDVPRFIEMYREGVLPVD
                     RLLTGTLPLEEVNAGFDRLHTGEAVRQVVLF"
     aSDomain        20800..21597
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2865_RS28180_PKS_ER.1"
                     /evalue="8.50E-11"
                     /label="C2865_RS28180_PKS_ER.1"
                     /locus_tag="C2865_RS28180"
                     /protein_end="289"
                     /protein_start="23"
                     /score="33.5"
                     /tool="antismash"
                     /translation="LEVTEVTLDPPGPGELLVRIGAAGLCHSDLSVINGSRVRPLPMAL
                     GHEAAGEVVEAGEGAEFAVGDRVVLAFVPACGRCPRCRSGRPALCVPGAAANGAGTLLG
                     GGRRIDGGRINHHLGVSAFSDYAVVSQQSAVKVDSDLPFEIAALFGCAVLTGAGAALHS
                     AQVAPADSVAVFGLGGVGLSALLAAKALGAETIVAIDVVPAKLELARELGATHTVAGGP
                     DAVAELKEITGGGADKVIETAGVVPVLRQAYDAAAPGGTTVTVG"
     gene            complement(21860..22465)
                     /locus_tag="C2865_RS28185"
     CDS             complement(21860..22465)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF036525.5"
                     /locus_tag="C2865_RS28185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_106401617.1"
                     /transl_table=11
                     /translation="MAAETVQEAWADLPPTAQRLLMAALDAFGEQGYHGTSTRQVALRA
                     GMSPAAMYMHFATKEALLYEIARTGHEVNSEQVRRACEEHPDPVERVRAIVEVMVSFHA
                     EHHTLARVVQYEHTSLSPARQRELIVIRRRTEAFLREAIDEGVAAGLFEAAAAPMATTA
                     IMSLAIDVARWYPSQRSRGADQITAAYADLALRMLASR"
     gene            complement(22522..23283)
                     /locus_tag="C2865_RS28190"
     CDS             complement(22522..23283)
                     /NRPS_PKS="Domain: PKS_KR (9-186). E-value: 1.5e-13. Score:
                     43.0. Matches aSDomain:
                     nrpspksdomains_C2865_RS28190_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018656505.1"
                     /locus_tag="C2865_RS28190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_106401618.1"
                     /sec_met_domain="adh_short (E-value: 1e-35, bitscore:
                     118.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.5e-30, bitscore:
                     100.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLFRLDGKTALVTGGTRGIGLMIARGLLEAGAARVVISSRKAAA
                     VDEAVAELSKVGGGEVVGVPADLSTEEECLRLAGTVEGPLHILVNNAGATWGAPLEEFP
                     SSAWDKVIDLNLKSPFYLTKALVPRLREAATADDPARIINIGSIDGIMTPGQRYSYTSS
                     KAAVHQLTRVLAKELGPQAITVNAIAPGPFESKMMAATLDAFGEAIAEAVPLKRIGRPD
                     DMAGAAVFLASRAGSYVNGAVIPVDGGLTVA"
     aSDomain        complement(22726..23256)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2865_RS28190_PKS_KR.1"
                     /evalue="1.50E-13"
                     /label="C2865_RS28190_PKS_KR.1"
                     /locus_tag="C2865_RS28190"
                     /protein_end="186"
                     /protein_start="9"
                     /score="43.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGGTRGIGLMIARGLLEAGAARVVISSRKAAAVDEAVAELS
                     KVGGGEVVGVPADLSTEEECLRLAGTVEGPLHILVNNAGATWGAPLEEFPSSAWDKVID
                     LNLKSPFYLTKALVPRLREAATADDPARIINIGSIDGIMTPGQRYSYTSSKAAVHQLTR
                     VLAKELGPQAITVN"
     CDS_motif       complement(23161..23250)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2865_RS28190_0001"
                     /evalue="6.10E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="C2865_RS28190"
                     /protein_end="41"
                     /protein_start="11"
                     /score="34.9"
                     /tool="antismash"
                     /translation="LVTGGTRGIGLMIARGLLEAGAARVVISSR"
     gene            complement(23350..23952)
                     /locus_tag="C2865_RS28195"
     CDS             complement(23350..23952)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016207.5"
                     /locus_tag="C2865_RS28195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FMN-binding negative transcriptional regulator"
                     /protein_id="WP_106401619.1"
                     /transl_table=11
                     /translation="MTYVPERMPQPSRARAAEFAKGIGFGSVFVEASRLAVAHVPIQVV
                     LDEGTGLPAEVVFHFSVKNELVGLLAGSARALLVFRGPDGYISPRWYDQESFPTWDYAF
                     VHMTGLAGPVAEARLRRHIKDLVERFDPGLAFGEEFIDRYIGGIRGFSMSFPEVEPLFK
                     LSQDKNEASVNGVLRGLRRRGESLDGRLADAIEAVRR"
     misc_feature    complement(23939..23952)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.4"
                     /tool="antismash"
     gene            complement(24023..24508)
                     /locus_tag="C2865_RS28200"
     CDS             complement(24023..24508)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2865_RS28200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_106401620.1"
                     /transl_table=11
                     /translation="MKPSTAAWAGAASLLPYVVMKTYWAFGGTAGKPPGDLAAQFRENG
                     APEALVWMEQHGLDFTVLGAFAGMLLLAALVLPWGRRLPRWSLLFPGWACALLLTPYGL
                     ATMVAAPFGLTVGDAGGWSPWVGVIGGLAFAGLGASLAVCALPHRRSAGRTPVPENS"
ORIGIN
        1 gctcgccgcc tagacggtgc ccacgtagac ccagtccccc tcgacgcgga cgaacttgct
       61 gttctcctcc atccgccccc gccgtccccg ttccacgtag tgggcgcgga accgcacggt
      121 gccctcggtg tcgaaggggc cgcccctggc ggtctccagc acctccaggc ccgtccatct
      181 ggtccgccgg tcgacccccg tgccggcggg ccgggtggcg gggtgccacg tgcgccgcag
      241 gtagtccgag tcgcccacgc tgaaagcgct gtaccgcgaa cgcatcagcg cctcggccgt
      301 gggcgcgctg ctctcccctg cgtggaaccg accgcaacac cgctcgtagg gctcggaaag
      361 cccgcacgga cacttcgaag acattccctc attctccctt ctcccggccg ccgcgccatc
      421 ggggcccggt ggcggccgtg ccgcgccctt cccgtcaggg tccggtctcg gctccctcga
      481 ccttgtagcc gggaatggac ggccagcgga cggtgaggac gaccgactcc tcctccgcgt
      541 accaggagtg gtcgacgccc cggccccaga cgacgtagtc gccctgcttg ctcagcacca
      601 cgtcgcggcc ggggaactcc atgcggaacc ggccgctgat gaggaccagg agggcggtgc
      661 ggtgttcgcc gtgcacccat gcggcgcgcg tgtcgccggg cgggtgcacg ccccacttga
      721 tctcgacgtc ggtgctgtgc cgggcgtctc cctcgggcat gaagtgcccc aggagccagc
      781 cgcgctcctc gggcgcgtcg atgttggcgt tgcccacgta gatgtcgtct gtcacggcca
      841 gcgagactaa ccgagatcgc cggtggaccg ttcgacggcg acgggcgccg ccggtcagat
      901 gccgaggcgg gcggcgatgc cctccagcag gcagtcgagg ccgtgggcga agcgccattc
      961 ggcgtcgtcc ttgcgcgtgg ccgtcctgag gtacttctcg aaggcggggt agcggccggt
     1021 gcccgtgagc cagaccatcg tcggggcgag ctcggagcgc agcccgtcgc caccggccag
     1081 cccctcgtcg tcgatcagct cggtgacggc ggtctcgtag cccgtcgcgc cctccacata
     1141 ggcgtcgacg gccctgaaca cgctcatcat cgtgtcggcg tccatgtcgt ggccgtccag
     1201 cacggcgagc gcctgctcgg cgacggccat ccggttcggc gtgagcgcca gcttggcccg
     1261 caggggcagc cggccgagcc aggggtgcgc cagcgtcagc tcccgggtgc ggaaggccag
     1321 gtcccggagc gcctcgcgcc agccgagacc gtccggcgtc cacggctcgg cgtagacgtg
     1381 atcgaccatc aggtccagga ggtcgtcctt gccggacagg tagcggtagg gcgccatggg
     1441 ggcgacaccc agctcggcgg ccagccggcg catggtgacg gcctccagcc cctccgcgtc
     1501 ggcgagcgcg accgcggtcg aggcgatgcg ctcgggggac agcgtctgac gcggcgcggg
     1561 cgcgggacgc tccagccgct cccacagtga ccccggtttc tccgtaccca tgagtacaac
     1621 gtatcccaag tagacaacgt acatagcgat gtgtacgttg tatctcgatc aatacgacgt
     1681 acacacccag gggacggcca tgcacgaaat gaagatcgcg atcctcgtcg gcagcaccag
     1741 ggacggccgc ttcgcccctt ccgtcgccgc gtggacggag agcctgatcg ccgagcgcgg
     1801 ggacatgcgg gccgacgtca tcgacctggt cgagaccccg ctgccgaccg tcttccccgt
     1861 cctcggccag ccgcccgcgt ccgccgcgga ccgggaactg ctggccgcgg tgtcgccccg
     1921 cctggccgag gccgacgcct tcgtcatcgt gacgcccgag tacaaccaca gctttcccgc
     1981 ggcgctgaag aacgcgatcg actggcacaa caccgaatgg cacgccaagc cggtcgcctt
     2041 cgtctcctat ggcgccttct cgggcggcct gcgggcgatc gagcagctgc gcccggtcct
     2101 cgccgaagtg cacgcggtgg cgatccgcga cgccgtctcc ctccagagcc cgtgggagca
     2161 gttcgacggc gacggccgtg cagtggaccc ggccgtcgaa gccgccggca ggctcatgct
     2221 cgaccgcctc gcctggtgga cgcacgcgct gcgcaccgcc cgcgccgcca ccccctacgc
     2281 cgcctgacat ggacgacctc gcccgaaccg agcgccggtc cctccacgcc ggtgtgttcg
     2341 gcctgctgct cggcatgttc ctggcgatgc tcgacgggct ggtcgtgggc accgcgctgc
     2401 ccacgatcgc cggggacctc ggcgggctgg accggctgcc ctgggtggtg accgcgtaca
     2461 tgctcgccgc cgcggccacc acccccgtct ggggcaagct cggcgacctg ttcggccgca
     2521 aggcggtctt cgtcaccgcg atcgtgctct tcctggccgg gtccgtcctg tgcggcctgg
     2581 cacgggacat ggcccagctc atcggtttcc gcgccgtgca ggggctgggc gcgggcgggc
     2641 tcatggtcgg ggcgctcgcc gtcatcggcg tgctggtccc gccccgcgac agcggccgga
     2701 tccagtcgat gatcggcgtc atcatgccga tcgcctacgt cggcggcccg ctgctcggcg
     2761 gcctgctcac cgaccatctg agctggcgct ggacgttcta cgtgaacgtg cccgtcggcg
     2821 cggtggccct cctgctcatc gcgacccgcg tccacccgcc gcccgccccg cgcgggcggc
     2881 cccgcatcga ctacgcgggc gccgccctgc tgacggcctc catcgtggcg ctgaccctgc
     2941 tcgcgagctg ggccgggacc gcctacccgt gggcctcgcc gcagatcctc ggcctgggcg
     3001 cggccggcgt cctcggcgtc gcctggttcg tcgccgtcga gcgtcgggcg gccgagccga
     3061 tcatcccgcc gcggctgttc gccgaccgcg acttcaccgt cgtgcaggtt ctcgggttcc
     3121 tcgtcggcgc cgcgatgctg accgtgacca actacctgcc gcagtacttc cagttcgtgc
     3181 agggcgcgtc tccggccgcc gccggcatgc tcctgctccc gctgatgttc ggcatgctcg
     3241 gcgcccagct gctcaccggc cgcctcatca gcgccgacgg ccgctaccgg cgctacccga
     3301 tcctcggcgg cgccctcatg accgcgggcg tcctcgccct gctccagctc ggcacgggca
     3361 cccccgcgcc cgccgcctcg gccctcacgt tcctcatcgg ggccggaatc ggcctgctga
     3421 tgcagagcag cacgctcatc accatgaaca gcgccgaccc gcgcgacatg ggcgccgcca
     3481 acggcaccct catgctgttc cgcaccatcg gcggctcgct gggcatcgcc ctcctgggca
     3541 ccctctacgc cgcccgcatg gccgccgacc tgaccgcccg cctgggaccg tccacggccg
     3601 cgcacctcac cgaaggcggc gccctcaccc ccgccctcct ccccgccctg ccggcggaga
     3661 ccgtcgatgc cgtccgctcc gccgtcaccg gcggtctcca cctcatcctc tacggcaccc
     3721 tcgtcctggc cctcctcacc ttcgccgcct cctggctcat ccgtgaggtc cccctccgca
     3781 ccgccctccc cccgtccacc cccgaaccgc accggtcacc ggccgaccga tgaggacgag
     3841 cccgccagcg cgtgtacagc cacgggcagg acgccgccag acggacgtcc gtcagtggaa
     3901 cgtccaacgc gcgccagcgc gtgtacagcc acgggcagga cgccgccagg cggacgtccg
     3961 tcagtggatg agggcgtggt tctcggcgtc ggtgcggcgg aggcgggcgg cgatggcgtt
     4021 ggcgatggac cagcgcagcg cgtcggccag gcgcggggag tcgcgttcca gccgggccag
     4081 ttcccgggtg gtgagcacca ggcaggaggt ggggcattcg gcgacgatgc ggtgggtgtg
     4141 ctcggcgtcg tcgatcaggg ccaggcggcc cacggcggtg ccggggccca tggaggtctc
     4201 gcggacgggg cgaggcgggg tgcccaccat gatctgccgg gccaggccgc cggagatgat
     4261 gaagcacagt gcggcgacgt cctccaggag gcgctcgccg ggggcgtact cgcgcggctc
     4321 caggtaggcc tccagggcgg tgaccaggaa cgggtcgagg ctgcgcagca ggtcctgttc
     4381 ggccagcgga acggtcatgc gggaggcgcc cgcggactcc agcagggcgt cctcgcacca
     4441 ctccagcgcg gcgtccctgg tctcggagat gaccgcggag gggacggtga cgcccttctc
     4501 cgtgtcgacg acgaccgtgg tgatgccgcg ttccttcagt ttggcggcca ggccctccat
     4561 gagggtctcg gcgaccgagg cgacccgccc ggcgcgtttg aggtccagga cgacccagcg
     4621 gacggagccg gtgtcctcgc tgatggtgcg cacgaccgcc tcggcgctgc tgaacgccag
     4681 gtcgccgcgg agcacgtaga cgcggatggc gccgccgagg cgggccaggg cggtgcgttc
     4741 gtcgtgggcg cggacccggg aggagtgcgc ggtgtcgccg cgcagggtgc ggtggaagac
     4801 cggtccggaa cgttcggcgg ggcgcatcag gtgcagcccg aaccgctggg acagctcctc
     4861 gcaggccgcg acgccgcgca cgctgttgcc gcgtgagtcc aggcgggggc tgaagaggcc
     4921 gagcccgagc tgggagggca gcgcggcgat gagcccgccg gacacgccgc tcttggcggg
     4981 cagcccggcg cggaccagcc actcgcccgc gtagtcgtag gtgccgcagg tggccatgac
     5041 ggtcagcgcg ttggccgccg cctccaccga cacgacggtc tcgccggtca gcgggttgat
     5101 gccgcctccg gcgagggtgg cggtcatgac ggcgaggtcg ctggtggtca ccagcgccgc
     5161 gcactgctcg aagtacagcc gcagcgactc ctcgacgtcg caggtgaggg tgcccgcgcc
     5221 gtgcatgagg taggccaggg cgcggttgcg gtcgccggtg gccgcctcgg agtccatcac
     5281 cttgcggtcg acggccagtt cgcgtccggc gaaggccgac aggcccgtca ggatgcgctc
     5341 ccggcgctcc tcgaaggtgt cgccgccgac gagggtggag gtgacgatgg cgccggagtt
     5401 gaccatgggg ttgtagggac ggccggtgta gggctcgagg cggacggcgt tgaaggcgtc
     5461 tccggtgggc tcgacgccga cctgcttgag cacgtcgggc aggccgcggt cctgcagggc
     5521 cagggcgtag acgaacggct tggacaccga ctggatcgtg aacggcaccc ggctgtcgcc
     5581 cgcctcgtag acggtcccgt cgagggtggc gacggcgagc ccgaaccatt cggggtcggc
     5641 cttgcccagc tccgggatgt aggtggcgac ctcaccggcg cgctgctcga tgagacgggc
     5701 gtgcaggtcg tccaggaggt cctggatcgg gctgacaaat ggcgcgttca ctcccacagg
     5761 gtaacgagaa ggctcactcc cggagatcac cggtatccgt atccggacac gccgccgtcc
     5821 cggccaggag cgccgcctcg gccatgcggc gcagcaggcg cgccatgccc gcgcggtcca
     5881 gctccccggc gctgtgcggg gtggagttga gcagcccgaa caccgcgtgg acggcggcgc
     5941 gggcctcgtc ctccgggcgg ggccactgct cgcgcgtcac ccgtacccat tcctcgacgt
     6001 aggcgcgctg caggcggcgg atctcccgcc gcggggcctc ggggacgttc tccagttcgc
     6061 gctcgtgcac gacgatgagc gccgggtggt ccagcgcgaa ggagatgtgc cagtccagca
     6121 gggcgccgag cgggtcggcg gcggccgcgg cgcgccggaa cccctcgtcg tgcagccggg
     6181 cgctgatgtc cagcaggatc tcggccagca gcgcctcctt gccggcgaag tgccggtaca
     6241 gcgcgggccc ggtgaggccg acggaggcgc cgagctcgcc gatggacacc ccgtggtagc
     6301 cgcgccgggc gaacagctcg gcggccgcgg ccaggatctg cgcccgcctg gcccgggtat
     6361 cgatctccat gcccccagtg tagacgacgc agttaatgat gattaacatc gttgttagtg
     6421 accattaaca tgggtgccgc cgccgcgcgg ccccgccggc cgtatcgacc ggatcgagcg
     6481 attcgatgga ggagggacac gttgggagtg ctgccgagcc gggcggacgc cgcgggcgag
     6541 ccctacaagc gcaacgccga ggcgaacgcc gaactcgccg cccagctgcg ggaacggctg
     6601 gcggccaccg ccctgggcgg gtccgcccgc gcccgcgagc ggcacgtgtc ccggggcaag
     6661 ctgctgcccc gcgaacgggt cgaccggctg ctggacccgg gttcgccctt cctggagctg
     6721 tccccgctgg ccgcctgggg cctgtacgac ggccaggcgc ccggagccgg gatgatcacc
     6781 ggcgtgggcc gggtctccgg gcgcgagtgc gtggtcatcg ccaacgacgc gacggtcaag
     6841 gggggtacgt acttcccgat gaccgtcaag aagcacctgc gggcgcagga ggtggcgctg
     6901 cacaaccggc tgccgtccat cgccctggtc gactccggcg gcgcgttcct gccgatgcag
     6961 gacgaggtct tccccgaccg cgagcacttc ggccggatct tctacaacca ggccaacctc
     7021 tcggcgctgg gcgtggcgca gctggccgcc gtcatgggct cgtgcaccgc gggcggtgcc
     7081 tacgtgccgg cgatgagcga cgagaacgtc atcgtccgga accagggaac gatcttcctg
     7141 ggcggcccgc cgctggtgaa ggccgccacc ggcgaggtcg tcaccgccga ggagctgggc
     7201 ggcggcgacg tgcactcccg ggtctccggg gtcaccgacc acctggccga ggacgacgcc
     7261 gacgccctgc gcatcctgcg ggagatcgtc gcgacgctcg gcccgcgccc gccccgcccg
     7321 tgggacgtcc ggccgtccgc cgagcccctc tacgacccgt ccgagctgta cgggatcgtc
     7381 ccggcggacc cgcgcacgcc ctatgacgtg cgggaggtcg tcgcccgcgt ggtggacggc
     7441 agcgagttca ccgagttcaa gaaggagtac gggccgacgc tcgtgaccgg cttcgcccga
     7501 atccagggcc acccggtggg gatcatcgcc aacaacggca tcctgttcgc cgagtcggcg
     7561 atgaagggcg cgcacttcat cgagctgtgc gaccgccgct cgatcccgct ggtgttcctg
     7621 cagaacatca ccggcttcat ggtcggccgc gactacgagc acggcggcat cgccaagcac
     7681 ggcgccaaga tggtcaccgc cgtctcctgc gcccgggtgc cgaagttcac cgtgatcatc
     7741 ggcggctcct acggcgccgg caactacgcc atgtgcggcc gcgcgtactc gccccggttc
     7801 ctgtggatgt ggcccaacgc ccggatctcg gtgatgggcg gcgagcaggc cgcctcggtg
     7861 ctgaccaccg tcggcgacgc cgacgccgac gccgtccggg agcagtacga gacgcagggc
     7921 gagccgtact actccaccgc ccgcctgtgg gacgacggcg tgatcgaccc cgtcgacacc
     7981 cgccgggtcc tcggcctggc cctgtccgcg gccgccaacg cccccctcgc cgacgtcggc
     8041 tacggcgtct tccggatgtg aggcccatgt tcaccaccgt cctcatcgcc aaccgcggcg
     8101 agatcgccgt ccgcgtccag cgcaccctgc gccgcctggg cgtgcgctcc gtcgccgtgt
     8161 acgcgcccga cgacgccggc tccgtccatg tacgggaggc cgacgaggcc gtgcggatcc
     8221 cgtcctacct ggacggcgcg gcgatcatcg aggccgcgcg ggccaccagc gcccaggccg
     8281 tccatcccgg ttacgggttc ctggccgaga acgccgcctt cgcccgtgcc tgcgccgagg
     8341 cgggggtcgt cttcatcggc cctccgcctt cggccatcga cgccatgggc gacaagatcg
     8401 aggccaagct gaccgtcgcc gccgcggggg tgccggtcgt gccgggccgc gacgagcggg
     8461 ggctgagcga cgagcagatc gccgaggccg ccctggagat cggcctgccg gtgctgctca
     8521 agccgtcggc gggcggcggc ggcaagggca tgcgcctggt gcgcgccgaa gaggagctgg
     8581 ccggggcgat cgcctcggcg cggcgcgagg cgcgcggcgc gttcggcgac gacaccctgc
     8641 tggccgagcg gttcatcgac gggccccgcc acatcgaggt gcaggtcttc gccgacgcgc
     8701 acggcaacgt cgtgcacctg ggcgagcggg agtgcagcct gcagcgccgc caccagaaga
     8761 tcgtggagga ggcgccctct cccctgctgg acgccgcgca gcgggccgag atcggcgcgc
     8821 acgcggtgaa cgcggcacgc tccatcggct acgtcggcgc gggcaccgtg gagttcatcg
     8881 tggcgggcga acggcccgac gagcgctact tcatggagat gaacacccgc cttcaggtcg
     8941 agcacccggt gacggaactg gtcaccggcc tggacctggt cgagctgcag ctgcgggtgg
     9001 cctccggcga gcccctgccg ttcacccagg acgacgtcgt gctcaccggg cacgccgtcg
     9061 aggcccgcgt ctacgccgag gacccggcgc ggggcttcct gccgaccggc ggccgcgtcc
     9121 tggcgctcgc cgagcccgcg caggcccggg tggactccgg catcggcgcg ggcgacgaga
     9181 tcggcagccg gtacgacccg atgatcgcca aggtggtcgt gcacgggagg gaccgggccg
     9241 aggcgctgcg ggcgctggac cgcgccctgg ccgagtactc gctgctgggc gtgcacacca
     9301 acgtcgcctt cctgcgcagg ctgctggccc ggcccgaggt cgtctcgggc gagctggaca
     9361 ccggcctggt cgagcgggtc ctgccggagc tgaacgccgg cgacgccacc gttcccgagt
     9421 gggtgctcgc cgccgccgcg ctggagcgga tgcgcgcgga cgcccctgcc ggggacggcc
     9481 cgtgggacgc catggacggc tggcgggtcg gcgaggccgc gtggaccccg cacgcgctgg
     9541 tcgtcgacgg cggcgagccg gtcgaggcgc ggaccagggg cgaggaggtc gccgtcgggg
     9601 acgggcctcc ccggcacgcg gtcctgtccg gggaggccct ggtgctcgac gggcgccgcc
     9661 acccgcaccg ccgcgccacc ggtcacgacg gcgcggtctg gatcggcgcg gacgggcgga
     9721 cctggtcggt ccgcgagcgg gagcggctgg cggccggcgg cgcgtcggcc gtggccgggg
     9781 gcgtgctgcg cagtccgatg cccggcaccg tcctggccgt gaaggtcgcc gagggcgacg
     9841 ccgtcgccga gggccagccg gtcgtgatcg tcgaggcgat gaagatggag cacacggtcg
     9901 tggccgccgt cgccgggacc gtcgcccggc tgccggtccg cgtcggcgac caggtggcgc
     9961 tcgacgccgt cctggccgag atcacgtccg aggaggcgga atgaacctgc ccgaacaggt
    10021 caccatctac gaggtcggtc cccgcgacgg cctgcagaac gagaagaccg ccattcccgt
    10081 ggaggtgaag gccgagttca tcggccggct cgccgacgcc gggttgaaga ccatcgaggc
    10141 gaccagcttc gtgcatccca agtgggtgcc gcagctggcc gacgcggacg agctgctgaa
    10201 gcggatggac cgccggcccg gggtgtccta cccggtgctg gtgcccaacg agcgcggcat
    10261 gggccgcgcg ctggccgccg gggtcggcga gatcgcgatc ttcgccagcg ccaccgagtc
    10321 cttcgcccag cgcaacctca accgctccat ggacgagcag tacgccatgt tcgagccggt
    10381 cgtctcccgg gcgctggccg agggcatgcg ggtgcgggtg tacctgtcga tggccttcgg
    10441 cgacccgtgg gagggcgacg tgccggtccc gcaggtcgtc gccgccggga agcggctgct
    10501 ggagatgggc tgctaccagc tcagcctcgg cgacaccatc ggcgtcggca ccgccgggca
    10561 cgtccaggag ctcatcgcgg ccttcggcga ccccgccgca ctggccgtgc acttccacga
    10621 cacctacggg caggcgctcg ccaacacgct ggccgccctg cagtcgggcg tcaccaccgt
    10681 cgacgcctcc gccggaggac tcggcggctg cccgtacgcc gagagcgcca cagggaacct
    10741 cgccaccgag gacctggtct ggatgctcga cggcctgggg atccggcacg gcgtgtccct
    10801 ggactccctg gtcgagacca gcacctggat ggccgggagg ctcggccgtc cctccccttc
    10861 ccgcgtcgtc accgcaagga gcaactcatg atcgacttca ccctcaccga ggagcaggag
    10921 gcgctgcggc agagcgtcga ggcgttcgcc cgcgaggcgg tctcccccgt catcggcggc
    10981 cactacgagc ggggcgagtt cccctacgag ctggtcgccg gcatggggaa gatgggcctg
    11041 ttcgggctgc cgttccccga ggagtacggc ggcatgggcg gagactactt cgcgttgtgc
    11101 ctggcgctgg aggagctggc gcgggtggac tcctcggtcg ccatcaccct ggaggccggc
    11161 gtcggcctgg gcgcgatgcc gatctaccgg ttcggcaccg aggagcagaa gcgcaggtac
    11221 ctgccgaagc tgctcaccgg tgagcggctg gccgggttcg ggctgaccga gccgggcggc
    11281 ggctcggacg tgccgggcgg catgcgcacc acggcccggc tggaggacgg ccagtgggtg
    11341 gtcaacggct cgaagtgctt catcaccaac tccggcaccg acatcaccga gttcgtcacg
    11401 gtcaccgcgc tgaccggcga gaacgagatc tccacgatca tcgtccccaa cggcacgccc
    11461 ggcttcaccg tggggccgga gtactccaag gtcggctggc gcgcctcgga cacccgcgag
    11521 ctgttcttcg acgacgtgcg cgtcccggag gagaacctgg tgggcccgcg cggccgcggc
    11581 tacgcccagt tcctgcgcat cctggacgag ggccgcatcg cgatcgccgc gctgtcggtc
    11641 ggcctggcgc agggctgcgt cgacgagtcc ctgcgctacg tcaaggagcg gcaggcgttc
    11701 ggccgggcga tcggcgagta ccaggcgatc cagttcaaga tcgccgacat ggagcagcgg
    11761 gtgtggaccg cccgcgtggc ctactatgcg gcggcggcga ggatgctgcg cggcgagccg
    11821 ttcaagaagg aggccgcgat cgccaagctg accgcctcca acgccgcgat ggacaactcc
    11881 cgcgacgcca cgcagatctt cggcggctac ggcttcatga acgagttccc ggtgggccgc
    11941 ttctaccggg acgccaagat cctggagatc ggcgagggca cctccgaggt ccagcgcatg
    12001 atcatctctc gccagctggg gcttgcatga tcacgctgaa ccggcacggg cacgtcgccg
    12061 agatcgtcct ggaccgtccg aaggcgcaca acgcgctgtc caccgagatg gccgtccggc
    12121 tcgcctccgt gtgcgcggag gtcgcggatt ccgacgcgcg cgccgtcgtc ctgtcgtcct
    12181 ccgccgagaa gtccttctgc gtgggcgcgg acctgaagga acgcgcctcg atgactgacg
    12241 acgacctgat gcgccagcgt ccggtcttcc gcagagcctt cggcgccgtc ctgcacctgc
    12301 cgcagcccgt cgtggcggcc gtccacggct tcgccctggg cggcggcacg gagttcgcgc
    12361 tctcctgcga cctcgtcgtc gccgacccga cggccgtctt cgggctgccc gaggtcggcg
    12421 tcgggctgat cccggcaggc ggcggcaccc agctgctgca gcgccgggtg ggcacggcca
    12481 aggccgccga cctcatcttc accggccgca aggtcggctt cgacgaggcc gtcgccctgg
    12541 gcctggtgga ccgcccggcg cccgcgggcg aggaccgcgc ggccgcgctg gagctggccg
    12601 ggaccatcgc ggccaactcc ccggtggcgc tgcgcgcggc caagcgggcg ctgcgccacg
    12661 gcgccccgct ggacctggcc gcggccctgg acgtcgagga cgccgcctgg cgcaccgccg
    12721 cgctgtccgg cgaccgccgc gagggcatcg ccgcgttcaa cgagaagcgc cgcccggagt
    12781 ggccgggact gtgaaccggc gcgcctgatt aaatctatta cgtctgggaa acgccgtttc
    12841 aaaatagccg ggaggccgcc gtgcaggagg gcatcaccct gtgggagccg tcgcaggaga
    12901 ccgtcgaacg ggcgaggatc accgcgttca tgcgggcgct gccgtcgcgg cctcgtgact
    12961 acgacgagct gtggcgctgg tcggtggcgg acgtcgacgg gttctggcag acggtctggg
    13021 accacttcca gatcgtcggg gaccgcggtg acgggccggt gcgcgagggc gggcccaccc
    13081 cggtggacgg gctgcgctgg ttcccctcgg cgcggttgaa ctatgccgag aacatgttgc
    13141 ggcacgccgc cgagcggccc gaccgcacgg ccgtcgtcta ccgcaccgac gacggcacca
    13201 cggtggagct cacctgggcc cggctggccg agcaggtggc cggggcgcgg gcgggcctgg
    13261 ccgcgctcgg cgtcggccgc ggcgaccggg tcgcgggcta cctgccgaac cggccggagg
    13321 cattggtcgt catgctggcg gcggcctcgc tgggcgcggc ctggtcgtcg tgctccccgg
    13381 acttcggggc gccgagcgtc atcgaccggt tccagcagat cgagccgaag gtcctgctcg
    13441 cggtggacgg ctacgtctac aacggcaggg tcttcgaccg gcgcgagacc ctcgcggaga
    13501 tccgcgcggc cctgccgacg ctggccgcca ccgtgctgat cgacgtcgtc cccggcgagc
    13561 cggtggcggg cgcgctcccc tacgacgagc tcgcacggcc cgccgagccc gccttcgacc
    13621 gggtgccgtt cgaccagccg ctgtggatcc tgtactcgtc cgggacgacc gggctgccca
    13681 agccgatcgt ccacgggcac ggcgggatgg tgctggagca cgtcaagtcc ctcgccctgc
    13741 accaggacct cggcccggac gacgtgttcc tgtggttcac caccaccggc tggatgatgt
    13801 ggaactacct ggtcagcggc ctgatgctgg gcgcgaccat cgtcctgttc gacggagcgc
    13861 ccgccgggga ggtgttgtgg cggctggccg ccgagaccgg caccacccat ctgggcctgg
    13921 gcgccccgta catcatggcc tcccgcaagg cggggctcac gccgggcgcg agcctggacc
    13981 tgtcggcgct gcggctgatc ggctcgaccg gctcgccgct gccgcccgag gggttctcct
    14041 gggtgtacga ggaggtcaag cgggacgtgc tgctgggctc gctgtcgggc ggcacggacg
    14101 tgtgctcggg gttcgtggga ccggtgccgc tgctgccggt gcgcgccggg gtgatccagt
    14161 gccgcgcgct cggcgcgaag atcgaggcgt tcgacgaggc gggccgcccg gtcgtggacg
    14221 aggtcggcga gctggtgctg accgagccga tgccgtgcat gcccgtcggg ttctggaacg
    14281 acccggggaa cgtgcgctac cgggaggcgt actttgagga cttccccggc gtatggcggc
    14341 acggcgactg ggtgaaggtg ctccccgacg gcggctgcgt catctacggg cggtcggact
    14401 ccaccctcaa ccggggcggt atccgcatgg gcaccagcga cttctaccgg gtggtggagt
    14461 cgttcgagga gatcgccgac agcctggtca tcgacaccgg cgggctcggc gcggagggcg
    14521 agctgatcct gtacgtgcag ctcgccccgg gcgcggagct gggcgaggag ctgctgggcc
    14581 ggttgcgggc ggcgctgcgc gccgacctct cgccccggca cgtgcccgac cgcttcgtgc
    14641 cggtccccgg ggtgcctcgc acgttgtcgg gcaagaagct cgaggtcccc gtccgcaaga
    14701 tcctccaggg cgtcgacccg gacaaggcgg tcaaccgcgg ctccctcgcc gacccgtcgg
    14761 tcctcgacca ctacgtgccg gacgcctccg catgaccggc ccgcactcga ccggccgcca
    14821 caggagacgg cagactgccg cccatgagaa cagaacgtga ttcggccgag ggtctgcggg
    14881 agctgaggaa cgaggtcaga tcgttcgtcc gggagtggca ggaggagggc cgcttcgccc
    14941 cccgctgcga ctcctggctg cgcgagcacg acaccgcctt ctcccgcgcc cttgccgggc
    15001 gcggctggat cgggctcacc tggccccgcg agtacggcgg ggccgagcgc tcccacctcg
    15061 cccggctcgt cgtcaccgag gagctgctgc gggcgggcgc cccggtggcc gcgcactgga
    15121 tggccgaccg gcagatcggg cccgcgatcc tgcggcacgg ctcggccgga ctgaagcggc
    15181 ggttcctgcc cggcatcacc cgcggcgaga tcaccttctg cgtcgcgatg agcgagaccg
    15241 aggccggcag cgacctggcg gccgtgcgca ccaccgccgc ccgcaccggc gaagggtggc
    15301 tgctcaacgg gcgcaaggtc tggacgagcc acgcccaccg ctccacccac gcctacgtcc
    15361 tggcgcgcac cgacgcgacc ggccgcaagc acgaggggct cagcgagttc ctgctggacc
    15421 tggcgacgcc cggtgtgacc gtccggcccc tcttcgacct ctccggggag caccacttca
    15481 acgaggtgtt cttcgacgac gtgctcatcc cccatgaccg gttgctgggc gtcgagggcc
    15541 agggctggaa gcaggtcacc gagcagctgt cgttcgaacg cggcggcgcg gaacgggtgc
    15601 tcagcaccta tcccctgctc gcggcgttcg tcgccgacgt cgaccccggc gactccctgg
    15661 ccgtccaggc cgccggggag ctgaccgccc ggctgtccgt gctgcgggcg atggcctggc
    15721 gggtggccgc cgacatggac gaggggcgcg cacccatcag ggaggccgcc ctgctgaagt
    15781 cgctgggcac cgccttcgag aaggacgtcg tcgagaccgt ccggcgggtc cgcggcgccc
    15841 tgcccgaccc ggacggcggc gggctggaac ggctgatggc ccaggccgtg cccgccgttc
    15901 ccggtttcag cctgcgcggc ggcaccacgg agatcctcgg cacgatcgtc gccaagggcc
    15961 tcacctcgga cgcgccctcc cggccgggcc ggacgccgct cggcgagctg gcggcggacg
    16021 tcctggccgg gcgcgggcag gaccccggcc tgtgggagga gctgcgcgag ctgggctggg
    16081 cgggcgcggg cctgccggag gagctcggcg gtgagggcgg caccctgacg gaactgctga
    16141 ccctgctgga ggcggtcggc gaacacggtg ccgccgtccc gctcctggag acctccctgg
    16201 cctgccggct gctcgtccgg gccggccggc ccctccccgc ccggatgacc gccacggtcg
    16261 cactgcccgg acccgggctg cggacgggcg agacgctcga cgggacgatc gaacgcgtgc
    16321 cctgggcgtc cgccgccgac ctggtcgtcg tgccgctcga cggggagctg gtgctgctgg
    16381 acggcaccgt ccccggctgg cgggtcgaac ccgggcggaa cctggccggc gagccccgcg
    16441 acacggtcca cctggacggg tgccggatcc cgcccggcca ccggatcgcc tgcgacgtct
    16501 cccgcgagga ggtcgtggaa cgggccgccc tcctgcaggg ggcccagctc gtcggggccc
    16561 tgcgcaccgc gctgcggctc gccgccgacc acgcccgcac ccgcgagcag ttcggccgcc
    16621 ccctcgcggc gttccaggcg gtctccctga cgctggccgg agccgccgcc cgcgtcgagg
    16681 gcgccgagac cgcgctggca cgggcggccg aggccgggac gggcgccccg gtggcggcgc
    16741 tgcgcctgtg gctggccgag gccgcgggag aggtcgccgc cgccgcccac caggtgcacg
    16801 gcgcgatggg cgtcacccgc gaacaccccc tgcaccacac gacccgcaga ctgtgggcgt
    16861 ggcgggacga atgggccgac gcccggcact gggccggggc actcgcccgc gccgccgggc
    16921 cggggcccgg cgacgaccgg ttgtggggat cgaccggcgt ggacgtacaa gtggccgtac
    16981 aggcagacgt acaggacgat cgaggaggac gggcatgagc cggtggaaga cgctgcggct
    17041 ggagagccgc gacggcgggg tgcgggtgct gacgctggac gacccggcgc ggcacaacgc
    17101 catcagcttc gcgatgcgcg acgacctcgt cgactgcgcc gcccggctgc gggccgacca
    17161 tgacgcgcgg gtcctgatcg tcacgggagc gggccggtcg ttctgctccg gcgcggacct
    17221 gggcgagctc ttcggtgccg aggacctgcc ggtgcgggag atccgcgacg acgccgcccg
    17281 catgtacgac gccttcctgg ccgtacggga cctgcccatc ccgacgatcg ccgcggtgca
    17341 gggccacgcg atcggcgcgg gcctgaacct ggcgatgtcc tgcgacgtgc ggctggccgc
    17401 gccgcaggcg aagttcagcg cgacgttcag ccggatcggc ctgcatcccg gcggcggctg
    17461 cacctacttc ctggtcgagg cactgggccg ccagcgcgcc ctggccgtcc tcctggaggg
    17521 cggcaccctc gcgggcgagc aggccgtccg gcacggcctg gccctggaac tgcacgacga
    17581 ccccctggcc gccgccctgg agatggccgg caggttcgcc tccgtgccgc cggggctggc
    17641 ccgcgacatc aagaccgccg tcgggctggc cgccacccag ggcttcgagg ccaccctcgc
    17701 cttcgaggcc tgggcgcagg cggactcctc cacccggccc gccacccgcg aaaccctgaa
    17761 ccgcaccttc cgcaggccct gacaccgggg aacgttctga gaggatggtc tctgaccggc
    17821 gaaaaaggga ggcacgaggc acatggcgca gcgggtacgc ggggtcgtcg caccgggcag
    17881 gaacgaaccc gtacgggtgg agacgatcat cattccggac ccggggccgg gcgaggccgt
    17941 ggtgaaggtc caggcgtgcg gggtgtgcca cacggacctg cactacaagc agggcgggat
    18001 caacgacgag ttcccgttcc tgctgggcca cgaggcggcg gggatcgtgg agtccgtggg
    18061 cgacggggtc accgaggtcg cgcccggtga cttcgtggtc ctcaactggc gggccgtctg
    18121 cggccagtgc cgcgcctgcc tgcgcgggcg tccgtggtac tgcttcaaca cccacaacgc
    18181 caagcagaag atgaccctgg aggacggcac cgagctgtcg cccgcgctgg ggatcggggc
    18241 cttcgccgac aagaccctgg tggccgccgg gcagtgcacc aaggtcgacc ccgcggccaa
    18301 gccggaggtc gcgggtctcc tcggctgcgg ggtgatggcc gggatcggcg ccgccatcaa
    18361 caccggcggc gtcacccggg gcgactcggt cgcggtcatc gggtgcggcg gcgtcggcgg
    18421 ggcctcgatc atgggggcgc ggctggccgg agcgcggcgg atcatcgccg tggacatcga
    18481 ccagcgcaag ctcgacaagg cgctcgagct gggcgcgacc cacaccgtca actccaagga
    18541 gaccgacgcg gtcgaggcga tccgggagct gaccggcggg ttcggcgcgg acgtcgtggt
    18601 tgaggccgtg ggccgtcccg agacgtatga gcaggcgttc tacgcccgtg acctggccgg
    18661 gaccgtcgtc ctggtcgggg tgccgacccc ggagatgagg ctggagctgc cgctgctgga
    18721 ggtcttcggc cgcggcgggg cgctgaagtc ctcctggtac ggcgactgcc tgccctcgcg
    18781 ggacttcccc atgctcatcg acctgtacct gcagggccgc ctcgacctcg gggcgttcgt
    18841 caccgagacc atcggcatcg atggcatcga ggccgcgttc gccaagatgc accacggcga
    18901 cgtgctgcgc tcggtggtga tcctgtgacc gccgccatca gccacctggt cacctccggc
    18961 accttctccc tggacggcgg catctgggac gtcgacaaca acgtctggat catcggcgac
    19021 gagcacgagg ccatcgtcat cgacgccgcc cacgacgccg ccgccatccg cgacgcgctg
    19081 ggcggacgca ccctgaaggc catcgtctcc acccatgccc acaacgacca catcgacgcg
    19141 gcccccgtcc tcgccgacgc cacgaacgcg ccgatcctgc tgcacccggc cgacctgccg
    19201 ctgtgggaga tgacgcaccc ggaccggcgg cccgacgggg agctggccga cgggcaggcc
    19261 ctgaccgtcg gcgggatcga gctgaaggtc ctgcacaccc cgggccacgc gcccggcgcc
    19321 gtctgcctgt acgcgccgga gctgggcacg gtcttcaccg gcgacaccct cttccagggc
    19381 ggtccgggcg cgaccgggcg ctcgttctcg gacttcccga ccatcatcgg ctccatccgg
    19441 gagaagctgc tgaccctgcc cggcgacacg aaggtgtaca ccgggcacgg cgactccacc
    19501 aggatcgggg acgaggcccc gcatctgcag gagtggctcg accggggcca ctgagcctcc
    19561 ggtgatacgg gggcgggccg cggtcggcgg tccgcccggc atgacacgat gcggtcatgg
    19621 aactgctcga ggctctgcgc ggcaccgccg ccatcaggga gttcacggag gaacccgtct
    19681 ccgacgccgt cgtccaccgc atcctggaca ccgcccggtt cgcgcccagc ggcggcaaca
    19741 agcagggatg gcgggtcgtc gtcgtcaagg accccgaggt ccgcgcgaag atgcgcgacc
    19801 tgtacctgcc gggctggcgg gactaccggg cgctgggcga ggcggggctg cgggcgtggt
    19861 cgccgctggc cgaccgggag gccgaggccg cggcgctgga ccgggagccc gccgaggacc
    19921 accgtgccga cttcgcgctc aacatggaca aggtgccggt gatgctcgcc gtgttcgccg
    19981 acctgaacga gctggcggcc gtcgaccgcg accacgaccg ctacacgttc gcgggcggcg
    20041 cgtcggtcta cccgttcgtg tggaacctgc tcctcgcggc gcgcgaggag ggcctgggcg
    20101 gggtgatgac gacgatccac atccgccagg aggagggtgt gcgcgaactg ctgggggctc
    20161 cggacggcgt cgcgctggcg tcggtggtgt tcctgggcca tccggtgcgc aggccgacac
    20221 ggctgcggcg tgcggcggtg tcggagttcg ccactttcga ctccttcgat gggagccccg
    20281 tcacaccacc cgatgttact gaccagtagg atagtttccc gtgagctacc tgtactggga
    20341 gagcgtcccg acccgctgga acgacaacga ctgctacggc cacatgaaca acgtcatcca
    20401 ctacgagatg atggacaccg tggccaacac ctggctcatc cgcgaggcgg gcttcgaccc
    20461 gttccacggt gacaccatcg gcatgtgcgt ggcatcccgc tgcgagtata aggccgaggc
    20521 ccgcttcccc gaggtcatca gggtggggtt gcgcatcggc aggctcggca cctccagcgt
    20581 caggtacgag atcggcctgc accgcgccga cggcgagacc ctcatcgccc acggcgactt
    20641 cacccacgtc ttcgtcgacc gcgagacccg ccgtcccgtg ccgatcaccg ggcggatgcg
    20701 cgaggccatg gagaagctgg tggtggcgtc atgaccagga cccgggtgtc ggtgctgacc
    20761 gaactcggca gggaggcgcc ctacgcggcc tcccggccgc tggaggtcac cgaggtgacg
    20821 ctcgacccgc cggggccggg cgagctgctg gtgcggatcg gcgcggcggg actgtgccac
    20881 tccgacctgt cggtgatcaa cgggtcgcgg gtgcggccgc tgccgatggc gctggggcac
    20941 gaggccgccg gcgaggtcgt cgaggccggt gagggagcgg agttcgccgt cggcgaccgt
    21001 gtcgtgctgg cgttcgtgcc ggcctgcggg cggtgccccc gctgccggtc cgggcggccc
    21061 gccctgtgcg tgccgggcgc ggcggccaac ggcgcgggca ccctgctggg cggcgggcgc
    21121 cgcatcgacg gcgggcggat caaccaccat ctgggcgtct cggcgttctc cgactacgcg
    21181 gtggtctccc agcagtcggc ggtcaaagtc gactccgacc tgccgttcga gatcgcggcg
    21241 ctgttcggct gcgcggtgct gaccggcgcg ggcgccgccc tgcacagcgc gcaggtcgcc
    21301 cccgccgaca gcgtcgccgt cttcgggctc ggcggcgtcg gcctgtcggc gctgctggcg
    21361 gccaaggccc tgggcgcgga gacgatcgtc gcgatcgacg tcgtgcccgc caagctggaa
    21421 ctcgcccgcg aactcggcgc cacccacacc gtggcgggcg gcccggacgc cgtcgcggag
    21481 ctcaaggaga tcaccggcgg cggcgcggac aaggtcatcg agaccgcggg cgtcgtgccg
    21541 gtgctgcgcc aggcctacga cgcggcggcc ccgggcggca ccaccgtcac cgtggggctg
    21601 cccgctcccg gcagggagct ggcgctgccc gcgctcagcc tcgtcgccga ggagaagacc
    21661 ctgcgcggca gctacctggg ctcctgcgcg ccccggcggg acgtcccccg cttcatcgag
    21721 atgtaccgcg agggcgtcct cccggtggac cggctgctga cgggcaccct gccgctggag
    21781 gaggtcaacg cgggcttcga ccggctgcac accggcgagg ccgtccggca ggtcgtgctc
    21841 ttctgacggt cccgtcccgc tagcgggacg ccagcatgcg cagcgccagg tcggcgtagg
    21901 ccgcggtgat ctggtccgcg ccgcggctgc gctggctggg gtaccagcgg gccacgtcga
    21961 tcgccaggga catgatcgcc gtggtggcca tgggcgccgc cgcggcctcg aacagcccgg
    22021 ccgcgacgcc ctcgtcgatc gcctcgcgca ggaaggcctc ggtccgccgc cggatcacga
    22081 tcagctcccg ctggcgggcc ggggacaacg aggtgtgctc gtactgcacc acccgcgcca
    22141 gggtgtggtg ctcggcgtgg aaggagacca tcacctcgac gatggcgcgc acccgctcca
    22201 ccggatccgg atgctcttcg caggcccggc ggacctgctc ggagttcact tcgtgcccgg
    22261 tgcgcgcgat ctcgtacagc agcgcttctt tggtggcgaa gtgcatgtac atcgcggccg
    22321 ggctcatccc cgcacgcaac gccacctggc gggtcgaagt cccgtggtaa ccctgctcgc
    22381 cgaaggcgtc cagcgcggcc atcagcagcc tctgcgccgt gggcggcagg tccgcccaag
    22441 cctcctggac ggtctcagcc gccatgcgcc gccactcctg tactcgcccg gatcccggca
    22501 cgggccggga gtcaccagag actaggcgac cgtcaggccg ccgtccacgg gaatcaccgc
    22561 accgttcacg tacgacccgg cgcggctggc gaggaacacg gcggcgcccg ccatgtcgtc
    22621 ggggcggccg atgcgcttga gcggcaccgc ctcggcgatg gcttcgccga acgcgtcgag
    22681 cgtcgcggcc atcatcttgg actcgaacgg gccgggcgcg atcgcgttga cggtgatcgc
    22741 ctgcggtccg agctccttgg ccagcacccg ggtgagctgg tggaccgcgg ccttgctgga
    22801 ggtgtaggag tagcgctggc ccggcgtcat gatgccgtcg atcgagccga tgttgatgat
    22861 ccgcgccggg tcgtcggcgg tggcggcctc gcgcaggcgc ggcaccagcg ccttggtgag
    22921 gtagaagggg gacttcaggt tgaggtcgat gaccttgtcc caggccgagg aggggaactc
    22981 ctccagcggg gctccccagg tggcgccggc gttgttgacc aggatgtgca gcggcccctc
    23041 gacggtcccg gccagccgca ggcactcctc ctcggtggac aggtcggccg gcaccccgac
    23101 gacctccccg ccgccgacct tggagagctc ggcgacggcc tcgtccaccg cggcggcctt
    23161 gcgggagctg atgacgaccc tggccgcccc ggcctccagc aggccccggg cgatcatcag
    23221 cccgatgccc cgggtccccc cggtgaccag cgcggtcttg ccgtccagcc ggaacaggtc
    23281 catgagtcac tcccggtatg ccatgagagg tccgatacga gacccgcagt ctatcgagcg
    23341 gcagccggtc taccgccgca ccgcctcgat ggcgtccgcg agccgcccgt cgaggctctc
    23401 cccgcgtcgc cggagcccgc ggagcacgcc gttcaccgac gcctcgttct tgtcctggct
    23461 gagtttgaac aatggctcga cctcgggaaa ggacatcgag aatccgcgga taccgcctat
    23521 gtaccggtcg atgaattcct caccgaaggc caatccggga tcgaaacgct ccacgaggtc
    23581 cttgatatgg cggcgaagcc tggcctcggc gacgggcccg gcgaggcccg tcatgtgcac
    23641 gaaggcgtag tcccaggtgg ggaagctctc ctggtcgtac cagcgcgggg agatgtaccc
    23701 gtccggcccg cggaagacca ggagcgcccg cgccgacccc gccaggagcc cgaccagctc
    23761 gttcttgacg gagaagtgga agacgacctc ggcgggaagc cccgtgccct cgtcgaggac
    23821 cacctggatc ggcacgtgcg ccaccgcgag acgggacgcc tcgacgaaca ccgaaccgaa
    23881 tccgatgccc ttcgcgaatt ccgctgcccg tgccctgctc ggctgcggca tcctctcggg
    23941 aacgtatgtc atttcgacac tttcccatgc gccggcgcac ggcgacaaat acgcgggcca
    24001 ttcatcggca aataacggag atttatgaat tctccggcac gggtgtccta cctgcggagc
    24061 gccggtgggg cagggcgcac acggcgaggg acgcgcccag cccggcgaac gccaggccgc
    24121 cgatgacgcc cacccagggg gaccagcccc cggcgtcgcc cacggtgagg ccgaaggggg
    24181 cggcgaccat ggtggccagg ccgtacgggg tcagcaggag ggcgcaggcc cagccgggga
    24241 acaggagcga ccagcggggc agcctcctcc cccagggaag gaccagggcg gccaggagca
    24301 gcattccggc gaacgcgccc aggacggtga agtcgaggcc gtgctgctcc atccacacca
    24361 gcgcctcggg agcgccgttc tcccggaact gcgcggccag gtcgcccggc ggcttgccgg
    24421 ccgttccgcc gaacgcccaa taggtcttca tcactacgta ggggagcagg gacgcggctc
    24481 cggcccaggc ggccgtcgag ggcttcatgt cacagatcgt ggcagcgccc cgcggaaccc
    24541 gcttcccgcc ggagagccaa cccgctcccc cggcggggtg atccacctcc cgattcgggc
    24601 gtaggccctc cggatgaggg cgccgtccag gccgacgccc ccgtggaggg ctacaggggg
    24661 cgggcggcca gggcgcggtc caggcgttcg cgggcgcggg cggcctggcg ggctcggtag
    24721 gcgatcggca tgtagcgcag gcgctcgggc aggagggggg tggagcgggc gatggcctgg
    24781 cccgccacgt gcagg
//
