LOCUS       NZ_PVZV01000002        25064 bp    DNA     linear   CON 13-DEC-2024
DEFINITION  Actinocorallia populi strain A251 contig2, whole genome shotgun
            sequence.
ACCESSION   NZ_PVZV01000002
VERSION     NZ_PVZV01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinocorallia populi
  ORGANISM  Actinocorallia populi
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Thermomonosporaceae; Actinocorallia.
REFERENCE   1  (bases 1 to 1301122)
  AUTHORS   Li,X.
  TITLE     Actinocorallia populi sp. nov., an endophytic actinomycete isolated
            from a root of Populus adenopoda (Maxim.)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1301122)
  AUTHORS   Li,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) College of Light Industry, Textile and Food
            Engineering, Sichuan University, No. 24, First South Section First
            Ring Road, Chengdu, Sichuan 610065, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR MAR-2018
            Expected Final Version            :: yes
            Genome Coverage                   :: 221.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002995495.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 14:18:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,861
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,716
            CDSs (with protein)               :: 7,716
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 18 of 83
            Pseudo Genes (incomplete)         :: 70 of 83
            Pseudo Genes (internal stop)      :: 6 of 83
            Pseudo Genes (multiple problems)  :: 10 of 83
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:05:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 623310
            Orig. end                         :: 648374
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVZV01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25064
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25064
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25064
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15064]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15064
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    36..50
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.83"
                     /tool="antismash"
     misc_feature    complement(37..51)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.26"
                     /tool="antismash"
     misc_feature    94..109
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.58"
                     /tool="antismash"
     misc_feature    complement(116..130)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     misc_feature    complement(182..197)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    470..485
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.61"
                     /tool="antismash"
     misc_feature    complement(677..692)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            738..1592
                     /locus_tag="C2865_RS09865"
     CDS             738..1592
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853716.1"
                     /locus_tag="C2865_RS09865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_232835484.1"
                     /transl_table=11
                     /translation="MRSRLTPYLMVLPGGLWLLAFFAVPLVLMVSFSLMTGNIIEGFEQ
                     VFRWQNYTEGLELYGDKFVRSLWYGLLATTACLLLAYPAAAWIAFRAGSRKSVYLLLLL
                     LPFFVSFILRTVSWKFVLADNGIVLGTLKGWGVLPDGFHVLGTTFAVIAGLTYNFLPFM
                     VLPIYVALERLDPRVVEAAQDLYASRTQTFLRVVLPLSLPGVFAGVVMTFVPVSADYVN
                     ADVLGGPDNVMIGNVIWTEYFVNNDYPTASALSFTMMAILLAGIFLYARALGTEDVLEA
                     AKR"
     gene            1589..2371
                     /locus_tag="C2865_RS09870"
     CDS             1589..2371
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017590277.1"
                     /locus_tag="C2865_RS09870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_106398053.1"
                     /transl_table=11
                     /translation="MSARRGRGLQVYTWILVGWLVLPIAVMILFGFNDTTTRQNFVWEG
                     FTLKWYARLFEKPDLTQALVNSLFIAVLSTAVTTVLGTLIGLALGRYRFRGKGLSNVVL
                     FAAISSPELVMGASLLSMFVTLNVPRGIGTVVAAHVMFSIAFVAVTVRARAAGLDPALE
                     EAAADLGATRWETFRLVTLPMIMPGVLAGALLAFALSIDDFVITNFTSGTTVTFPLWVW
                     GSTRTGTPPQVNVMGTLIFAIGVLIAIVNVVAARRRKT"
     gene            2462..3871
                     /locus_tag="C2865_RS09875"
     CDS             2462..3871
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853714.1"
                     /locus_tag="C2865_RS09875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_106398054.1"
                     /sec_met_domain="DAO (E-value: 1.4e-52, bitscore: 175.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALKALAEAEPTPFWLQDPARPEPCPSLVETTACDLAVIGGGYT
                     GLWTALLAKERDPALDVVLVDADLAGEAASGRNGGFCAASLTHGLWNGMERWPRQIRTL
                     ERLGKENLAGIAATVAQYGIDCDFEFTGELKVATERWQLPELAREGRYGTALGHDMRLL
                     DRDEMRAEVDSPTYLGGLWDVEGAAMLHPARLAWGLREACAALGVRIYERTPVTSMESE
                     RLGVLLRTPYGRIKARKVALGTGAFPPLLKRLKHYLVPVYDYALMTEPLSQAQLDELGW
                     RNRQGLSDAANQFHYYRLTADNRILWGGYDAIYHFRNGIRAELESRPETFARLSRHFFT
                     TYPQLEGVSFTHSWGGVIDTCSRFCAFYGKAMGGRLAYAVGYTGLGVGAARFGAQVMLD
                     HLGVGPVTREQAERLRLEMVTGRPLPFPPEPLRFGAIQLTRWSIARADANQGRRNLWLR
                     TLDRFGLGFDS"
     gene            complement(3918..5198)
                     /locus_tag="C2865_RS09880"
     CDS             complement(3918..5198)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621806.1"
                     /locus_tag="C2865_RS09880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_106398055.1"
                     /transl_table=11
                     /translation="MVLAHGIGGRQDLPIPLSFLLAGAALAVLVSFMAVGVLWRDSRFD
                     GGRGRPVPAGLQSFADAAATRFVLRLAGVVLAVLTAAAALFGAGGAANPAPWTVYVLFW
                     VGLVPLSLLFGPVWKLLNPLRAVHAGLSLISGGRPLAQLPPWLGYWPAAVGLFAFTWLE
                     LIPPDREEGWALLTWFAVYAVVMTVGSLVFGAEFFDKGDPFEVYSGLIGRLAPLGRRPD
                     GRLVLRNPFDGLAGLKAAPGLVAVVCVMLGSTAYDGFSRSPWWAGQVQSGPLPRVLMGT
                     LGLAALVALVALTYWLCTRMIGPDAPGALAPSLIPIAIGYLVAHYFTLLVFGGQQAMKL
                     WTDPFVTQADYLGTRDWVIDYELLGDTAQAVIRAGAVVIGHVLGVFAAHDRAVELLPRN
                     RALTGQLPLLLLMVFFTVGGLALLFAT"
     gene            complement(5198..5629)
                     /locus_tag="C2865_RS09885"
     CDS             complement(5198..5629)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2865_RS09885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_106398056.1"
                     /transl_table=11
                     /translation="MFRARALVPVVALSLFAAACGGEEKEAAPSAPSSAAPSATASETA
                     AAPGTPSEPAFDGTLIKVDVNGNKVAPRPSTHKITKGDRVRIEVTSDKPDELHVHGYDN
                     TADLKAGETAVIEFTADQSGRFEVETHDSGLLLFNLEVS"
     gene            complement(5690..6220)
                     /locus_tag="C2865_RS09890"
     CDS             complement(5690..6220)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133762.1"
                     /locus_tag="C2865_RS09890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PH domain-containing protein"
                     /protein_id="WP_332873346.1"
                     /transl_table=11
                     /translation="MRFNQAMVIRERTRARVFRKYLMANEGNVIAVRRHPAVLLRYFCE
                     TLGGLIVAGALTGWLGGGAAAAVIWIAWLLVLGRLLWKLLTWTVEFFIVTDLRLMYIRG
                     LVARRVGMIPRGKVTDIKMERTVLGEILDYGTFIMESAGDDQAFREVTFMPYPEQLYYE
                     VSSAIFSAESIDD"
     gene            6329..6781
                     /locus_tag="C2865_RS09895"
     CDS             6329..6781
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012698.5"
                     /locus_tag="C2865_RS09895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_106398057.1"
                     /transl_table=11
                     /translation="MDSTTFAAKVEGLAPGEGRLLGVVPMEGTRTALVVVGHLVDLDTG
                     NGAPPLPLPPHDGDGLSVDPVARAVRADGRAVPLTYQEFELLAHLTASPGRVHSRGQLL
                     RAVWGHTDAGSLRTVDVHIHRLRSKLGGYRQRIVTVRRLGYMYTKR"
     gene            6896..9199
                     /locus_tag="C2865_RS09900"
     CDS             6896..9199
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019974.5"
                     /locus_tag="C2865_RS09900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_106398058.1"
                     /transl_table=11
                     /translation="MALLKPRMRSIRARIALLLIIPLLSLVGLWGFALSLTFPDARGKF
                     RIDTAYEGIGLSAASLMGTLQYERKLSAVHVASEQGTDGQLYQQLVMVRGEVDKHLNSY
                     REKALTEEMRDAVGERTSRLIDDFSTRLDGLTELRGNVDNRKIDAAAVAAAYTQSIGAS
                     LGVFESLVLADDVELYRKSDALISYTYAREFVMQEDTMVSAALAGDGRLTKDQFRTFAI
                     LVAGQQQMTRMSRENLGAEVAPLMAEVVNSPHYATLGQLERAVQGAADGDSGRLPASLA
                     QQWPGTVEQLLKLWETNVNKAGAILKGDAEPIGDRVIWRLSVAAGAGLLAVAVSIALSV
                     TLVRGLTREIGQLQNAARELAEQRLPWVVGRLRRGETVDVAREVPPLDIGARTTEVARV
                     ADAFNRVQNTAMQTAVGEAHLRKGISRVFLNLAWRSQSLLHRQLRMLDALERKAPDPDT
                     LNDLFQLDHLTTRMRRHAEGLIILSGSAPGRSWSKPVHMSDVLRGAVAEVEDYTRVEAV
                     SASPVALTGAAVTDVIHLLAELIENATAYSPPPTEVLVHGEVVGNGFAVEIVDRGVGLT
                     PAEFAELNERLAKAPEFDLADTDRLGLFVVSRLAARHGIKVTLQPSAYGGVSAVVVMPH
                     SLIVPESAIGDEQPSIEARRPTSTPAESGPWPVPPPSPAAPPKRSPAPVPTSLAPAGTA
                     SSVVPPREEGGLPRRVRQNSLAPQLRQGPLSAPPAEHPEPDDRDPEISRDLFSSLQAGW
                     QRARNENDEDGYGS"
     gene            9196..9615
                     /locus_tag="C2865_RS09905"
     CDS             9196..9615
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017614419.1"
                     /locus_tag="C2865_RS09905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_106398059.1"
                     /transl_table=11
                     /translation="MSNTRAATELSWLLDDLVNRVGEVRKAIVLSRDGLVMGSSQAVSR
                     EEGDHLAALASGLHSLAGGTRVHFGEGEVRQTIVELDTGLFFVAAAGSGSCLAVLSEAG
                     ANAGLVAYEMSMLVKRVRRLLSAAPRQPGAGDGQI"
     gene            9602..9976
                     /locus_tag="C2865_RS09910"
     CDS             9602..9976
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853133.1"
                     /locus_tag="C2865_RS09910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_106398060.1"
                     /transl_table=11
                     /translation="MGRFDERWVDDEAGPIVRSYAVVRGRTRPRGIALDLVTLLCATGR
                     EPPHDRRLSREESHLLALCWQPAAVADLASDLDLPLGVVKVLAGELCHLDLLEVRKPGR
                     RMVQADQALLQRVLEDLKAL"
     gene            complement(10001..11026)
                     /locus_tag="C2865_RS09915"
     CDS             complement(10001..11026)
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019993176.1"
                     /locus_tag="C2865_RS09915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_198653127.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.2e-58, bitscore:
                     193.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMPSALAPPDGVTGTLDETRRWMRPAMQEAVERLHPVPRLISGFT
                     LGWPTDGGRPRTGTGGKGVRPALAGLAAASAGGRAEDAAPGAAAVEFVHAFSLVHDDIM
                     DGDELRRHRQTAWKAYGIGPAVLAGDGLLALALDTLAQSGNTAALLRLTSVLVELVNGQ
                     AADTDFEGRPWSGPGAVTVEEYRAMAVGKTGSLLGCAASVGWLLGGGDREGAERMDRMG
                     RHLGLAFQAVDDLLGIWGEPEVTGKAVHNDLRRGKKSLPVVAALRSGDEELVRLLEARP
                     AKEDEALRAALLIERAGGRAYAEQTAERETAAALAIIEEIGGPRRDDLAALARYVVARR
                     V"
     misc_feature    complement(11137..11150)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.2"
                     /tool="antismash"
     misc_feature    complement(11147..11160)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.63"
                     /tool="antismash"
     misc_feature    11173..11190
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.48"
                     /tool="antismash"
     misc_feature    11203..11218
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.67"
                     /tool="antismash"
     misc_feature    complement(11248..11266)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.3"
                     /tool="antismash"
     gene            11361..12719
                     /locus_tag="C2865_RS09920"
     CDS             11361..12719
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="C2865_RS09920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_332873347.1"
                     /sec_met_domain="p450 (E-value: 1.9e-60, bitscore: 201.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALSTPARSAVKARSLPIYRDIPSLLRDPLNSFAEWGRQADGEIV
                     RLDAKVCRPYLITAPDHVQHILRGNQANYARGGIFYSPLKDLFGDGILGADDGQTWVHS
                     RRIMQPMFTARHIKLIQSRIAGFVKEGLDALEEPARTGTPVDVEDLMASIVTKAVVGLI
                     FGQRIGREQADELTAATNTLIPSMIPRVVTPFLPEWVPRPKDRVFAEAIRVFDKHMYEV
                     AAAEPQEGDDDLLTLFLGAPGPDGGPPSPKWLRDNFSGVYGAASESTVSAMVWLMPILA
                     RHPEVYAKLTAEIDEVIGADEMSPEHLPRLVYTKQVIDELLRYMPVGWLFSRVAVDEDV
                     IDGVRIPRGADILISPFISHRSEKYWDRPLEFDPERFAPGAPAPNRYSYFPFGAGGHLC
                     IGNHLFATEALLLLAGLFSRFRLVNVTPTEPTRVVGATIKPLEKVEMVVRPAR"
     gene            12744..13580
                     /locus_tag="C2865_RS39070"
     CDS             12744..13580
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654756.1"
                     /locus_tag="C2865_RS39070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="terpene synthase family protein"
                     /protein_id="WP_157963646.1"
                     /sec_met_domain="T1TS (E-value: 1e-12, bitscore: 44.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDLLNARSCGAAAAVGGQSQRRMRAWAQKYPGLYDKPEFDPALF
                     GTLAQAAAFSGPWYDADQLTAANKTCLWAFGLDWLVDYQAQSEEEVGALLARVASVADG
                     AEPEDELTAFLAELRDDLPPDPALRTIWREELQDMLDGMALEWRWKSRGPRPSLEEYLD
                     NADNLGFAFVFFAHWIANGASGEPAEVRKASRAVQQVIRLLNDLGTYERDLQWGDLNAL
                     LLGVDRPAVERKVAELSAEAVRLLEPLPPEHGGYMRRQMEFCSGFYGVTDYWGVEF"
     gene            13577..15064
                     /locus_tag="C2865_RS09925"
     CDS             13577..15064
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133479.1"
                     /locus_tag="C2865_RS09925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_198653128.1"
                     /sec_met_domain="T2TS (E-value: 1.8e-80, bitscore: 267.2,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRDVDRRAQELVDGLLAEPWGQVSPSVYETGRLVAFTPWLAGHA
                     ERVAFLLRTQRPDGGWGPDGEPGYLLVPSLSAIDALLAEGSAEAAAAAHRGLDRMRPLL
                     AAPPQLPDTPAIELISASLIRSIDSRLPGALPAPAALDDGTLDLVMAAAKQGGPLPQKM
                     WHALEIIGPAAAGLPGVPVENMGGVGAAPAATAAWLGGTEPPPSDPSRRFLETAARQHG
                     GPVACGLPITVFERSWVLTLLSRAGLAFDPHPELLLSLSAPLGPDGVATGPGLPPDADT
                     TSAVLYALTLLGRRVAPDPLTGYETETNFRTWPGGEQGRSVTTNAHVLEVFGQHARLEP
                     GAGHEATAAKVAAWLREVQRADGSWTDRWHASPYYATMATALALAEFGGEESADSVRAA
                     LRWVRDTQRPDGSWGVWGGTAEESAYALHVLLLAGDPEDAVEQVRAGAGFLAGAADDEP
                     PALWHDKDLYLPVAIVRAAVLAASHLAQVQLGGTLVT"
     misc_feature    15211..15228
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.53"
                     /tool="antismash"
     misc_feature    15222..15239
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.0"
                     /tool="antismash"
     gene            15308..17584
                     /locus_tag="C2865_RS09930"
     CDS             15308..17584
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133478.1"
                     /locus_tag="C2865_RS09930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_232835485.1"
                     /transl_table=11
                     /translation="MRTKITALLLSLTALWVFAAWVTLREGVNLLWVNQLDKGIAQPGD
                     VLIVDLQKERLLSMVLAGDRTQANADALRDQRTSTDRKRAAYLRDARSTMTKLAADDAL
                     EELLAQSFTALEDLDKARAWFDAPDGRSPDWARSLYTEAIGSMGLVYEGLATLDDDDFA
                     ARTRTLVELNQYNELFSQEDALVSGVLVAGRFTNASYADFHRLLGVQRHARAEVLERLA
                     EFAPETVERHEKSESLATVTALEDRLLAMMGNNHRKPIQTVSFAAWNNATTAWLAESQD
                     ITWDAGDQLVEAATPIATGVIIRLALAGGLGFLSVVASVILSVTTARHLVRQLERLKDA
                     AHELSDVRLPNVVERLGHGEQVDVEAEAPPLEFGDDDIGKVGQAFNAVQKTAIRTAVEQ
                     AELRRGIRDILLSLARRSQALVHRQLTLLDQMERREIDTEELEDLFRLDHLATRMRRNA
                     ENLIILSGATPARGWRRPVPMVDVVRSAVAEVEDYTRVTVMPIDEVHLVGRAVADIAHL
                     LAELIENAVSFSPPYTYAQISGHMVASGYALEIEDRGLGMSDENLAAINRKIADPPEFN
                     LSSSVQLGLYVVGKLAERYGVQVTLKRSPYKGTTAVVIIPRELLEEGESGAPSQQSLTV
                     VGATMPEVTDSTDPRSGERFTPVLVPSPPEETPTAPASAPLPVRENPSTAGPASEETEL
                     TPSGLPVRVPQASLAPPLRDEPVGEDEPAGEDPGRSPEEIRRIVGAFQSGTLRGRAASV
                     ESETE"
     gene            17584..17991
                     /locus_tag="C2865_RS09935"
     CDS             17584..17991
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019633192.1"
                     /locus_tag="C2865_RS09935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_198653129.1"
                     /transl_table=11
                     /translation="MQKTGAGADLAWLLDDLVKRVNEAEHAIVLSADGLLMAQSQGIGR
                     DDAEHLSAVAAGIQSLAKGAGERFGGGAVRQTIIEMRSAFLLVTVAGQGACLAVLSSED
                     ADVGLIAYEMAMMVTKLGHHLSTPARVTESA"
     gene            17988..18377
                     /locus_tag="C2865_RS09940"
     CDS             17988..18377
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019632364.1"
                     /locus_tag="C2865_RS09940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_232835486.1"
                     /transl_table=11
                     /translation="MTYPPQEPENERWLDESAGPLVRPYVMTSGRLQPVRGEFDLITLV
                     EATGPAPSVAIGLGPEHLAIIRLCQTLMSVAEITAHLDLPTGTVRVLLGDLLDKGLVTV
                     QEPQPEIDMQDLRMYQAVIDGLRAL"
     gene            18358..18948
                     /locus_tag="C2865_RS09945"
     CDS             18358..18948
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013130418.1"
                     /locus_tag="C2865_RS09945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_106398065.1"
                     /transl_table=11
                     /translation="MASAPSSAAGTRRRMPTAIKILVAGGFGAGKTTLVGAVSETEPLR
                     TEEVLTDRGVGVDDIEGVETKRTTTVAMDFGRITFGDEFVLYLFGTPGQERFWFMWDEV
                     ALGALGAVVLADTRRLADCFPAIDYFERRGTPFIVAVNCFEGAQRYEADEVKQALQIGP
                     GIPVLLCDARRKESSKEVLITLVQHAMKMRAAR"
     gene            complement(18955..19782)
                     /locus_tag="C2865_RS09950"
     CDS             complement(18955..19782)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017594412.1"
                     /locus_tag="C2865_RS09950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutamate ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_232835488.1"
                     /transl_table=11
                     /translation="MTTSMPGRLLSLLLATVLLLSLAVACGADRSPGVEGRKVLRIGVK
                     YDQPGIGLRSHGSFLGFDVDVASYVAERLGAERVEFVGLTSGQREEFLIGRKVDLVVAS
                     YSITPLRKTLVNFAGPYYVAHQDIMVRGGERDILGPRDLAGRKLCKSEGSNSWKRVVEE
                     LGIEAELVDAATYGECVQLLLDGGLDAVTTDDLILAGFALRRPGAFRMVNARFTDEKYG
                     IGLRKDDVSGCEAVNRAVTRMYQDGTAARLLAKWFGPTGLKTTTTVPQFEGCG"
     gene            complement(19779..21155)
                     /locus_tag="C2865_RS09955"
     CDS             complement(19779..21155)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018655244.1"
                     /locus_tag="C2865_RS09955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_232835489.1"
                     /transl_table=11
                     /translation="MISKVAGALRALRRTAGRSALPRTVPGHLRGWAAAALLAVIALVA
                     AVSTGLEDARQGLRLVGEDAGPQVVHTGHLYFALSDMDAQLAGLLLIGAEHDLGAGRDR
                     AQERYRARRGEAHRALLQAYEIAGTDRASRRTVRDVLNGLGRYEQLASRALLLNDQSGH
                     PAGPPPQNVLGVYRRATDLMRQDILPKAYNLTLENASVVRRAYVDERSHVLRSRVAVGV
                     TALVLLAVLAGLQVYLAYRFRRLLSPALAAATALTLVLGGWALLVLGSTSSHLRMAKEE
                     GFDPTLAFTRARAISNTAAADQTRFLLDPRRADTYAQVYFDTSQAIAYRESGNLADYYR
                     RLAEAPPELGFLGGVPQGSEVLIRYRAFQEQDERMRGLVRRGDEREAIALRTGLMTETF
                     TAYDQELSRLVAHRNADFEREVAAGAAALDGWNRGLPAAGIVLAALIVLGVWPRLAEYR
                     "
     gene            complement(21152..22372)
                     /locus_tag="C2865_RS40640"
     CDS             complement(21152..22372)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012708.5"
                     /locus_tag="C2865_RS40640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FHA domain-containing protein"
                     /protein_id="WP_232835490.1"
                     /transl_table=11
                     /translation="MTIRTPFTVSVDQNRYLPDGGTDLHAIISVTGTGDPFEPAEDVRL
                     RVAVPRGVVLRSLKQVLPAEEDLSARAVEDAPRSFDHSTGRWGRRETREYHLRLRVPVQ
                     DVGQRMRAARLTVLLGGEALGAADVFAEWTDDRTRCTRIDARVAHYTGQSELAARIQAG
                     LAAQQAGDAGTAAAELESAVQLARAQGNVPLATMLSRVIEGDETTCTFRLRRGAAPAPP
                     PVPASSPARSGPCPECALPGEGRFCEGCGHDFATGVPGPRPAAPEDFRSRWYVVISTDP
                     EYHRRILAESGPDAGRLPAPQGRPGLSSPLTGGRVLLGRRSTLRGTVPDIDLAVPTRDP
                     AVSRTHAVLISRDGRWCLVDPGSANGTRLNAGSAPVAVGAEIPLHEGDRIHVGAWTTLE
                     LRRESLS"
     gene            complement(22369..23295)
                     /locus_tag="C2865_RS09965"
     CDS             complement(22369..23295)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634867.1"
                     /locus_tag="C2865_RS09965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="protein phosphatase 2C domain-containing protein"
                     /protein_id="WP_106398066.1"
                     /transl_table=11
                     /translation="MPCPSCSAPVFAGDLFCEACGHRLSPAARPAAETVHHREIDLGDD
                     AAAVSDRGLRHSTNQDGMALSPIPGGLAAVLSDGVSASPRPEEASGTAVETGISVLTRE
                     LEAGADPRDATRTAALAAAKAVAGLAADPSSAPACTYVSAVTGELDGRPVITIGWIGDS
                     RAYWIGATGDELLTEDDSWAEHVIAHGMMSREEAYADRRAHMLVGWMGADAREIDVHVR
                     VYAPEVPGVLVVCTDGLWNYMASPLALAAALADPLADPVSGPLTGRRGRRTPLSVAREL
                     VRTALSGGGHDNITVAIIPVEGDGLEL"
     misc_feature    23346..23360
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.21"
                     /tool="antismash"
     misc_feature    24306..24320
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
ORIGIN
        1 gaccccgcct tcgacccggg caacaccttt acggtcccct acatgtcggg catcacgggc
       61 atcgcgtaca acaccaagta cgtcaaggag cccatcacca gctggtccga cctgctgaac
      121 ccgaagtaca agggcaagat cggcatgatg ggcgacagcc aggagctggg cagcgcaggg
      181 ctgttcctca tcggcgtcga cccggagaag tccacgcccg cggactggga gaaggccgcc
      241 gccaagctgc gcgagcagcg cccgctggtg cgcaagtact actaccagga ctacatcgag
      301 gccgtcacca agggcgacgt gtgggtgacg atggcctggt ccggcgacgc ctacagcctg
      361 gccggacccg aggtcgagtt cgtgatcccc gaggagggcg gcacgatctg gaccgacaac
      421 ctgtgcatcc ccaggaccgc cgagaacccg gtgtccgcgc tgaagatgat cgactacctg
      481 tgcgacccgg cggtcaacgc gccgctgacg gagttcatca cctacatcac gcccgtcccc
      541 ggcaccaagg acgtcctgag gcgcaaggca gacgccgcca ccggtgaggc gaaggaggag
      601 ctggaggagt tcctgagcag cccgctggtc taccccggtg aggcggacct ggccaagctg
      661 cgccgctacc ggaccctcga ccaggcggag aaggagcagt accagaagat cttcacgccg
      721 atcgtgcagg gctcgtagtg cgcagcaggc tcacccccta cctcatggtc ctgcccggcg
      781 ggttgtggct gctggcgttc ttcgccgttc cgctggtgct gatggtgtcg ttctccctga
      841 tgacagggaa catcatcgag ggcttcgagc aggtgttccg ctggcagaac tacaccgaag
      901 ggctggagct gtacggcgac aagttcgtcc ggtcgctctg gtacggcctg ctggcgacca
      961 ccgcctgcct gctgctggcc tacccggccg cggcctggat cgcgttccgc gcgggcagcc
     1021 gcaagtcggt gtacctgctg ctgttgctgc tgccgttctt cgtgtcgttc atcctgcgga
     1081 cggtgtcctg gaagttcgtg ctcgccgaca acgggatcgt gctcggcacg ctgaagggat
     1141 ggggggtgct gccggacggc ttccacgtcc tgggcaccac cttcgcggtg atcgcaggcc
     1201 tgacgtacaa cttcctgccg ttcatggtgc tgcccatcta cgtggcgctg gagcgcctcg
     1261 acccccgggt ggtcgaggcg gcgcaggacc tctacgcctc ccggacgcag acgttcctgc
     1321 gggtggtcct gccgctgtcg ctgccggggg tgttcgccgg ggtggtcatg acgttcgtgc
     1381 cggtctccgc cgactacgtc aacgccgacg tgctgggcgg cccggacaac gtgatgatcg
     1441 gcaacgtcat ctggacggag tacttcgtca acaacgacta cccgacggcc tcggcgctgt
     1501 cgttcacgat gatggcgatc ctgctcgcag gcatcttcct gtacgccagg gctctgggca
     1561 ccgaggacgt gctcgaggcg gcgaagcgat gagcgcgcgg cgcggcaggg gcctgcaggt
     1621 ctacacctgg atcctggtcg gctggctggt cctgccgatc gcggtgatga tcctgttcgg
     1681 cttcaacgac acgaccacca ggcagaactt cgtctgggag ggcttcacgc tcaagtggta
     1741 cgcccgcctg ttcgagaagc ccgacctcac ccaggcgctg gtcaactcgc tgttcatcgc
     1801 ggtgctgagc accgccgtca ccacggtcct gggcacgctg atcggcctgg cgctgggccg
     1861 ctaccgcttc cggggcaagg gtctgtcgaa cgtcgtgctg ttcgccgcga tctcctctcc
     1921 ggagctggtg atgggcgcgt cgctgctgtc gatgttcgtc accctgaacg tcccgcgcgg
     1981 catcgggacc gtggtggccg cgcacgtgat gttctccatc gcgttcgtgg cggtgacggt
     2041 gcgggccagg gcggcgggcc tcgatccggc cctggaggag gcggccgccg acctcggcgc
     2101 gacgcgctgg gagaccttcc gcctggtcac cctgccgatg atcatgccgg gggtgctcgc
     2161 cggcgcgctg ctggccttcg ccctgtccat cgacgacttc gtcatcacca acttcaccag
     2221 cgggaccacc gtgacgttcc cgctgtgggt gtgggggtcc acccgcaccg gaaccccgcc
     2281 ccaggtcaac gtgatgggca cgttgatctt cgccatcggc gtcctgatcg cgatcgtcaa
     2341 cgtggtcgca gcacgccgca ggaagacctg acacgtggcc ctagtcccgt ccggggaagg
     2401 atccgtcgca accgtggcac ggaccccggg cggggcccag gggacacaga agaaggaaat
     2461 agtgaacgcg ctcaaggctc tcgccgaggc ggagccgaca ccgttctggc tgcaagatcc
     2521 ggctcgtccc gagccctgtc cctcgctggt ggagacgacc gcctgcgacc tggccgtcat
     2581 cgggggcggc tacaccggtc tgtggaccgc gctgctggcc aaggaacgcg acccggcact
     2641 ggacgtggtg ctggtcgacg cggacctagc gggggaggcg gcctccggcc gcaacggcgg
     2701 cttctgcgcc gcctccctca cccacggtct gtggaacggg atggaacgct ggccgcgcca
     2761 gatcaggacg ctggagcggc tcggcaagga gaacctggcg gggatcgccg ccaccgtcgc
     2821 gcagtacgga atcgactgcg acttcgagtt caccggcgag ctgaaggtcg ccaccgagcg
     2881 gtggcagctg cccgaactgg cgcgggaggg ccggtacggc accgcgttgg gccacgacat
     2941 gcggctgctc gaccgggacg agatgcgcgc ggaggtggac tcgcccacct acctgggcgg
     3001 gctctgggac gtggagggtg ccgccatgct ccacccggcc cggctcgcgt ggggcctgcg
     3061 ggaggcctgc gccgcgctgg gcgtccggat ctacgagcgc acccccgtca cctcgatgga
     3121 gagcgagcgc ctgggggtcc tcctgcggac accctacggt cgcatcaagg cacgcaaggt
     3181 cgcgctgggc accggggcct tcccgccgct tcttaagcgg ctcaagcact acctggtacc
     3241 cgtctacgac tacgccctca tgaccgagcc cctgtcgcag gcccagctgg acgaactggg
     3301 ctggcgcaac aggcagggcc tgtcggacgc ggccaaccag ttccactact accggctgac
     3361 ggccgacaac cgcatcctgt ggggcggcta cgacgcgatc taccacttcc gcaacgggat
     3421 ccgcgcggag ctggagtccc gcccggagac gttcgcgcgc ctgtcgaggc acttcttcac
     3481 cacctatccg cagctcgaag gcgtgtcctt cacccacagc tggggcgggg tgatcgacac
     3541 ctgcagcagg ttctgcgcct tctacggaaa ggcgatgggc ggccggctcg cctacgccgt
     3601 cggctacacc gggctgggcg tgggcgccgc ccggttcggc gcccaggtca tgctcgacca
     3661 cctgggggtg gggccggtga cccgggagca ggccgagcgg ctgcggctgg agatggtgac
     3721 cggcaggccg ctgcctttcc cgcccgagcc gctgcgcttc ggggcgatcc agctgacccg
     3781 ctggtccatc gcacgggccg acgccaacca gggcaggcgc aacctgtggt tgcgcaccct
     3841 ggaccggttc gggctgggtt tcgacagctg agacgggaga cgggcgccgg gcgggggccg
     3901 cccggcgccg tccggtctca ggtggcgaac agcagggcca agccgccgac ggtgaagaag
     3961 accatcagca gcagcagggg aagctgcccg gtcagggccc ggttcctggg cagcagctcg
     4021 acggcgcggt cgtgcgcggc gaacacgccc aggacgtgcc cgatcaccac ggctccggcc
     4081 cggatgacgg cctgggcggt gtcgccgagg agttcgtagt cgatcaccca gtcgcgggtg
     4141 ccgaggtagt cggcctgggt gacgaacggg tcggtccaca acttcatcgc ctgctggccg
     4201 ccgaagacca ggagcgtgaa gtagtgcgct accaggtacc cgatcgcgat ggggatcagc
     4261 gacggcgcca gcgcgcccgg ggcgtccggg ccgatcatcc gggtgcacag ccagtaggtg
     4321 agcgccacca gcgccaccag cgcggccagc cccagcgtgc ccatcagcac gcgcggcagc
     4381 ggacccgact gcacctgccc ggcccaccag ggggagcggg agaacccgtc gtaggcggtg
     4441 gagccgagca tcacgcacac gaccgcgacc agtcccggcg cggccttcag accggccagc
     4501 ccgtcgaacg ggttgcgcag caccaggcgg ccgtcggggc ggcggcccag cggcgcgagc
     4561 cggccgatga gcccggagta gacctcgaac gggtcgccct tgtcgaagaa ctccgcgccg
     4621 aagaccagcg agccgacggt catgacgacc gcgtacaccg cgaaccaggt gagcagcgcc
     4681 cacccctcct cgcggtcggg cgggatgagc tccagccagg tgaaggcgaa caggccgacg
     4741 gcggcgggcc agtagcccag ccagggcggc agctgcgcca gcggcctgcc cccgctgatc
     4801 agggagaggc ccgcgtgcac ggcccgcagc gggttcagca gcttccagac cgggccgaac
     4861 agcagcgaca gcggcaccag gccgacccag aacaggacgt agaccgtcca gggggcgggg
     4921 ttggccgcgc cccccgcgcc gaacagcgcg gcggcggcgg tcaggacggc caggaccacg
     4981 ccggccagcc gcaggacgaa ccgggtggcc gccgcgtcgg cgaaggactg cagcccggcg
     5041 gggacgggcc gccccctccc gccgtcgaag cgggagtcgc gccacagcac gcccaccgcc
     5101 atgaaggaga ccagcacggc cagcgccgcc ccggccagca ggaacgacag ggggatcggc
     5161 aggtcctggc ggccgccgat cccgtgggcg aggaccatca ggagacctcg aggttgaaca
     5221 gcagcagccc ggagtcgtgg gtctccacct cgaaccggcc gctctggtcg gcggtgaact
     5281 cgatcaccgc ggtctcgccg gccttcaggt cggcggtgtt gtcgtagccg tggacatgga
     5341 gttcgtcggg cttgtcactg gtgacctcga tgcggaccct gtcacccttg gtgatcttgt
     5401 gggtggacgg gcggggcgcg accttgttcc cgttgacgtc caccttgatc agcgtcccgt
     5461 cgaaggcggg ctcgctcggg gtcccggggg ccgcggcggt ctcggacgcc gtcgccgacg
     5521 gggcggccga ggacggggcc gacggggcgg cctccttctc ctcgccgccg caggctgcgg
     5581 cgaacaggga caacgcgacg acggggacga gggcgcgggc gcggaacacg ggggactcct
     5641 gagctcgggg gaggctgacc ccggccagtc tagggacccc cggaggcggt cagtcgtcga
     5701 tgctctcggc ggagaagatc gcggaggaga cctcgtagta gagctgctcg gggtagggca
     5761 tgaaggtcac ctcccggaac gcctggtcgt ctccggcgct ctccatgatg aaggtgccgt
     5821 agtccaggat ctcgccgagc acggtgcgct ccatcttgat gtcggtgacc ttgccgcgcg
     5881 ggatcatgcc gacgcggcgg gcgacgagcc cgcggatgta catcaggcgg aggtcggtga
     5941 cgatgaagaa ctccaccgtc caggtgagca gtttccacag cagccggccc agtacgagga
     6001 gccaggcgat ccagatgacg gcggccgcgg cgccgccgcc gagccagccg gtgagggcgc
     6061 cggcgacgat gaggccgccg agcgtctcgc agaagtagcg cagcagcacg gccggatggc
     6121 ggcgcaccgc gatgacgttg ccttcgttcg ccatgaggta cttgcggaac acgcgggccc
     6181 tggttcgttc ccggatgacc atcgcctggt tgaagcgcac gcctttcagc atcgcacacg
     6241 agcggcccgc cgcccccgtc ccgcggcgcc gggttcggcc gcgcattaaa tctataaact
     6301 cgaccaacta ggtgggtaat atggcgtcat ggattccacc acattcgccg ccaaggtcga
     6361 gggcctcgcc ccgggcgagg ggcggctgct cggcgtcgtc cccatggaag gcacccgcac
     6421 cgcgctggtc gtcgtcggtc atctcgtgga cctggacacc gggaacgggg cgcccccgct
     6481 gccgctgccg ccgcacgacg gcgacggcct gtccgtcgac ccggtggccc gcgccgtgcg
     6541 ggcggacggg cgcgcggtcc cgctcaccta ccaggagttc gaactgctgg cccacctgac
     6601 ggccagtcct ggccgggtcc actccagggg ccagctcctg cgcgccgtgt gggggcacac
     6661 cgacgcgggt tcgctgcgga cggtggatgt gcacatccac cggcttcgga gcaagctggg
     6721 aggataccgc cagaggatcg tcacagtccg gcggttgggt tacatgtaca ccaaacgttg
     6781 acttctgctg acgggtttgt tgagtttgag gcaggttgac ctgcgatgcg cctgaagtgc
     6841 aacatgagct ttccgaacga cgggtgacgg ctataacagg attgcgcagg ttgccatggc
     6901 tctgctcaag ccccggatgc gcagcatccg ggcccggatc gccctgctgc tgatcatccc
     6961 gctgctctcg ctcgtgggcc tgtggggttt cgcgctctcc ctcaccttcc ccgacgcccg
     7021 gggcaagttc cggatcgaca ccgcgtacga gggtatcggc ctgtccgcgg cgtccctgat
     7081 ggggacactg cagtacgagc ggaagctgag cgccgtccac gtcgcgagcg agcagggcac
     7141 cgacggccag ctctaccagc agctcgtcat ggtgcgcggc gaggtggaca agcacctgaa
     7201 ctcctaccgc gagaaggcgc tcaccgagga gatgcgcgac gcggtcggcg agcggacctc
     7261 gaggctcatc gacgacttca gcacccggct cgacggcctc accgagctgc gcgggaacgt
     7321 cgacaaccgg aagatcgacg ccgccgcggt cgccgccgcc tacacccagt cgatcggcgc
     7381 ctcgctcggc gtcttcgaat cgctggtcct ggccgacgac gtcgagctct accgcaagag
     7441 cgacgcgctc atctcctaca cctacgcccg cgagttcgtc atgcaggagg acaccatggt
     7501 cagcgccgcc ctcgcgggcg acggacggct gaccaaggac cagttccgga ccttcgccat
     7561 cctcgtggcc gggcagcagc agatgacccg gatgtcgcgg gagaacctgg gggcggaggt
     7621 ggcgcccctc atggccgagg tcgtcaactc cccccactac gcgaccctcg gccagctgga
     7681 gagggcggtc cagggggcgg ccgacggcga ctccggacgg ctgcccgcct cgctcgcgca
     7741 gcagtggccg ggcacggtcg agcagctcct caagctgtgg gagaccaacg tcaacaaggc
     7801 cggcgcgatc ctcaagggcg acgccgagcc gatcggcgac cgggtcatct ggcggctgtc
     7861 cgtcgcggcc ggcgccgggc tcctggcggt cgccgtgtcc atcgcgctgt ccgtgacgct
     7921 cgtccgcggc ctcaccaggg agatcgggca gctgcagaac gccgcgcggg agctggccga
     7981 gcagcggctg ccctgggtcg tcggcaggct gcggcgcggc gagaccgtcg acgtggccag
     8041 ggaggtgccg ccgctggaca tcggcgcccg caccaccgag gtcgcccggg tggccgacgc
     8101 gttcaaccgg gtgcagaaca ccgccatgca gaccgcggtc ggcgaggcgc acctgcgcaa
     8161 gggcatcagc cgcgtcttcc tcaacctggc ctggcgcagc cagtcgctgc tgcaccggca
     8221 gctgcgcatg ctggacgcgc tggagcgcaa ggcgcccgac cccgacaccc tcaacgacct
     8281 gttccagctc gaccacctca ccacccgcat gcggcggcac gccgagggcc tcatcatcct
     8341 gtcgggctcc gcgcccggcc gctcctggag caagccggtg cacatgtcgg acgtgctgcg
     8401 cggcgcggtc gccgaggtcg aggactacac gcgggtcgag gcggtgtcgg cctccccggt
     8461 ggcgctcacc ggagccgccg tcaccgacgt catccacctg ctggccgagc tcatcgagaa
     8521 cgccaccgcc tactccccgc cgcccaccga ggtgctggtg cacggcgagg tcgtgggcaa
     8581 cgggttcgcc gtggagatcg tcgaccgcgg cgtgggcctc accccggcgg agttcgccga
     8641 gctcaacgag cgcctggcca aggcgcccga gttcgacctg gccgacaccg accggctcgg
     8701 cctgttcgtg gtctcgcggc tggcggcacg gcacggcatc aaggtgacgc tgcagccgtc
     8761 ggcgtacgga ggggtcagcg cggtcgtggt gatgccgcac tcgctgatcg tgccggagtc
     8821 ggcgatcggg gacgagcagc cctcgatcga ggcgcgccgc cccacgtcga cgccggcgga
     8881 atccggtccc tggccggtgc cgccgccctc tcccgccgcg cccccgaagc ggtcccccgc
     8941 ccccgtcccc acgagcctcg ccccggcggg cacggcgtcg agcgtcgtcc cgccgcgcga
     9001 ggaaggcggg ctgccccggc gcgtcaggca gaacagcctg gccccgcagc tgcgccaagg
     9061 ccccttgtcg gcgcctccgg ccgagcaccc cgagccggac gatcgcgacc ccgagatcag
     9121 ccgtgacctg ttcagttcgc tgcaggcggg ctggcagcgg gcccggaacg agaacgacga
     9181 ggacggatac ggatcatgag caacacccgt gcggcaaccg aactgagctg gctgctggac
     9241 gacctggtca accgggtcgg cgaagtgcgc aaggccatcg tcctgtcccg ggacgggctg
     9301 gtgatgggca gctcccaggc ggtgagccgg gaggagggcg accacctggc ggccctggcc
     9361 tccgggctgc acagcctggc cggggggacc cgggtgcact tcggcgaggg cgaggtccgg
     9421 cagacgatcg tcgagctgga caccggcctg ttcttcgtgg ccgcggccgg cagcgggagc
     9481 tgcctggcgg tgctgagcga ggccggcgcg aacgcgggac tggtcgcata cgagatgtcg
     9541 atgctggtca agcgggtgcg caggctgctc tcggcggcgc cgaggcagcc gggagccggc
     9601 gatgggcaga tttgacgagc gctgggtcga tgacgaggcg ggaccgatag tccggtccta
     9661 cgcggtggtc cggggccgta cccggccccg gggcatcgcg ctcgatctgg tgacgctgct
     9721 gtgcgcgacc gggagggagc cgccgcacga caggcggctc tcccgggagg agtcgcacct
     9781 gctggccctg tgctggcagc cggcggcggt cgcggacctg gcgtcggacc tcgacctgcc
     9841 gctgggcgtg gtgaaggtgc tcgccggaga gctctgccat ctggacctgc tggaggtgcg
     9901 caagcccggc cgccgcatgg tgcaggccga ccaggcgctc ctccagcggg tcctggagga
     9961 cctcaaggcg ctctgaggcc ctccgtccct ttcggacgcg ctagacgcgc cgcgcgacca
    10021 cgtaccgggc cagtgccgcc agatcgtcgc ggcggggccc gccgatctcc tcgatgatcg
    10081 ccagcgccgc cgccgtctcc cgctcggccg tctgctcggc gtacgccctg cccccggccc
    10141 gttcgatcag cagtgccgcc ctgagcgcct cgtcctcctt cgccggacgc gcctccagca
    10201 gccgcaccag ctcctcgtcc cccgaccgca gcgccgcgac gaccggcagg ctcttcttcc
    10261 cccggcgcag gtcgttgtgg acggccttgc cggtgacctc gggctcgccc cagatgccca
    10321 gcagatcgtc caccgcctgg aacgccagcc ccagatggcg gcccatccgg tccatcctct
    10381 ccgcgccctc gcggtcgccg ccgcccagca gccacccgac cgacgccgcg catcccagca
    10441 gcgacccggt cttgccgacg gccatcgcgc ggtactcctc cacggtcacc gcgccgggac
    10501 cgctccaggg ccggccctcg aaatcggtgt cggccgcctg cccgttgacg agctccacca
    10561 gcacggacgt cagccggagc aacgcggcgg tgttgccgct ttgggcgagg gtgtccagag
    10621 ccagggccag cagcccgtcc ccggccagga ccgcgggccc gatgccgtag gccttccacg
    10681 cggtctgccg gtgccgacgc agctcgtcgc cgtccatgat gtcgtcgtgc accagcgaga
    10741 aggcgtggac gaactccacg gccgccgcgc ccggtgcggc gtcctcggcg cgaccgccgg
    10801 cggaggcggc cgccagtccg gccagcgcgg gccggacgcc cttgcccccg gtgcccgtcc
    10861 gggggcggcc gccgtccgtc ggccagccga gggtgaatcc ggagatcagc cggggaacgg
    10921 gatgcagccg ctccacggcc tcctgcatgg ccggacgcat ccaccgcctc gtctcgtcca
    10981 gcgtccccgt gaccccgtcc ggcggggcga gcgcactcgg catcatcggc agccctttcc
    11041 actacaacag atcttcgcgt caactctggc aaagaaatac cgcggggtag gccattcatg
    11101 tttcattcgc gtaagcatcc tccgatgacc ggccgatcac ggagggttat ttcgagaaag
    11161 gtttgtcgca gatagttatg cgtttattac ccagcgtatc catgtgccat gcgtcacaat
    11221 ggcttgtctg ttgtgtcggc ttcgtacact cttgatctgt aaagtggatc atggaagact
    11281 tgcaagttgt cggatttgtc tgatctgatc caggttcggg tgttccctgg atgaaactgg
    11341 tgagaagagg cgtcggaccg atggccctga gtactcccgc gaggtcggct gtaaaggcgc
    11401 gcagtctgcc tatttaccga gacattccga gccttcttcg agacccgttg aactcattcg
    11461 cggaatgggg ccgccaggcg gacggcgaga tcgtccgcct tgacgcaaag gtctgcaggc
    11521 cgtatctgat caccgcgccg gaccatgtcc agcacatcct gcggggcaac caggccaact
    11581 acgcccgcgg cggcatcttc tactctccgc tgaaggacct gttcggtgac ggcatcctcg
    11641 gcgcggacga cggccagacc tgggtccaca gccgccggat catgcagccg atgttcacgg
    11701 cgcggcacat caagctcatc cagtcgcgga tcgcgggctt cgtcaaagag gggctggacg
    11761 cgctggagga gccggcccgc acgggcaccc cggtggacgt cgaggacctg atggcctcca
    11821 tcgtgaccaa ggccgtcgtc ggcctcatct tcggccagcg gatcggtcgc gagcaggcgg
    11881 acgaactgac cgcggcgacc aacaccctca tcccgtccat gatcccccgg gtggtcaccc
    11941 cgttcctgcc cgaatgggtc ccccggccca aggaccgcgt gttcgccgag gccatcaggg
    12001 tcttcgacaa gcacatgtac gaggtggcgg cggccgagcc gcaggagggc gacgacgacc
    12061 tgctcaccct gttcctggga gcccccggcc cggacggcgg cccgccctcg cccaagtggc
    12121 tgcgtgacaa cttctccggg gtctacggcg cggcgagcga gagcacggtc tcggcgatgg
    12181 tctggctgat gccgatcctg gcccggcacc cggaggtcta cgcgaagctg accgccgaga
    12241 tcgacgaggt catcggggcc gacgagatga gccccgagca ccttccccgc ctggtctaca
    12301 ccaagcaggt catcgacgag ctcctgcgct acatgccggt gggctggctg ttcagccggg
    12361 tcgcggtgga cgaggacgtg atcgacgggg tgcgcatccc ccggggcgcc gacatcctga
    12421 tcagcccgtt catcagccac cggagcgaga agtactggga ccggcccctg gagttcgacc
    12481 ccgagcggtt cgccccgggc gcgccggccc cgaaccggta ctcctacttc cccttcgggg
    12541 ccggcggcca cctgtgcatc ggcaaccacc tcttcgcgac ggaggcgctg ctgctgctgg
    12601 cggggctgtt cagcaggttc cgcctggtga acgtgacgcc gaccgaaccc acgcgggtgg
    12661 tgggggccac catcaagccg ctggagaagg tcgagatggt cgtgcggccc gcccgctgag
    12721 cccgaacgac acgaggacat gtggtgaacg acctgctcaa cgcccggagc tgcggagcgg
    12781 cggcggccgt cggaggccag tcgcaacgcc ggatgcgcgc ctgggcgcag aagtaccccg
    12841 gcctctacga caagccggag ttcgacccgg cgctgttcgg cacgctggcc caggcggctg
    12901 ccttcagcgg cccctggtac gacgccgacc agctcaccgc ggccaacaag acctgcctgt
    12961 gggcgttcgg gctggactgg ctcgtggact accaggcgca gagcgaggag gaggtcggcg
    13021 cgctgctggc ccgggtggcc tcggtggccg acggggcgga gccggaggac gagctcaccg
    13081 ccttcctcgc cgaactccgc gacgaccttc cgccggatcc cgccctgcgc acgatctggc
    13141 gggaggagct ccaggacatg ctcgacggga tggcgctgga gtggcgctgg aagagccgcg
    13201 ggccgcgccc ctccctcgag gagtacctgg acaacgccga caacctcgga ttcgccttcg
    13261 tcttcttcgc gcactggatc gccaacggcg cgtccggtga gcccgcggag gtccgcaagg
    13321 ccagccgggc cgtccagcag gtgatccggc tgctcaacga tctgggcacc tacgagcgcg
    13381 acctgcagtg gggcgacctc aacgcgctgc tgctgggggt ggaccggccg gccgtcgagc
    13441 ggaaggtcgc cgagctgtcc gcggaggcgg tgcggctgct ggagccgctc ccgccggagc
    13501 acggcggcta catgcgccgg cagatggagt tctgcagcgg tttctacggt gtcaccgact
    13561 actggggtgt cgaattttga tccgcgatgt cgaccgccgg gcccaggaac tggtggacgg
    13621 gctgctcgcc gagccctggg gccaggtctc gccgtcggta tacgagaccg ggcggctggt
    13681 ggccttcacc ccctggctgg ccgggcacgc cgaacgggtc gccttcctgc tgcgcacgca
    13741 gcggcccgac ggaggctggg gaccggacgg tgaaccgggc tacctcctgg tgccctcgct
    13801 cagcgcgatc gacgcgctgc tggccgaggg atcggccgag gcggcggccg ccgcccaccg
    13861 cggcctggac cggatgcgcc cgctgctggc cgcgccgccg cagctcccgg acaccccggc
    13921 gatcgaactg atatcggcct cgctgatccg ttcgatcgac tcccgtctgc ccggggcgct
    13981 gccggcgccc gcggcgctcg acgacggcac cctggacctg gtcatggccg ccgcgaagca
    14041 gggcgggccg ctgccgcaga agatgtggca cgcgctcgag atcatcggtc ccgccgcggc
    14101 cgggctgccc ggggtcccgg tggagaacat gggcggggtg ggcgcggcgc ccgccgcgac
    14161 cgccgcctgg ctgggcggga cggagccccc gccgtccgat ccctcccggc gcttcctgga
    14221 gaccgccgcc cgccagcacg gcggtccggt ggcctgcgga ctgccgatca ccgtcttcga
    14281 acggtcctgg gtgctgaccc tgctgagcag ggcggggctg gccttcgacc cccacccgga
    14341 gctgctgctg agcctgtccg cgccgctggg cccggacggc gtggccaccg gtcccggact
    14401 gcccccggac gccgacacca cctccgcggt cctctacgcc ctgacgctgc tgggcaggcg
    14461 cgtggcgccc gacccgctca ccgggtacga gacggagacc aacttccgca cgtggcccgg
    14521 tggcgagcag gggcgttcgg tgaccaccaa cgcccacgtg ctggaggtgt tcggccagca
    14581 cgcgcggctg gagcccggtg ccgggcacga ggccaccgcg gccaaggtcg cggcctggct
    14641 gcgggaggtg cagcgggccg acggctcctg gacggaccgc tggcacgcct cgccctacta
    14701 cgcgacgatg gcgacggccc tggccctggc ggagttcggg ggcgaggagt cggcggactc
    14761 ggtccgtgcg gccctgcgct gggtgcgcga cacccagcgc cctgacggct cctggggcgt
    14821 gtggggcgga accgcggagg agagcgccta cgccctgcac gtcctgctgc tcgccggcga
    14881 tccggaggac gcggtcgagc aggtgcgggc gggagccggc ttcctggcgg gcgccgcgga
    14941 cgacgagccg ccggcgctct ggcacgacaa ggacctgtac ctccccgtcg cgatcgtccg
    15001 ggccgctgtg ctggccgcct cccacctcgc tcaggtgcag ctcggcggca cactggtcac
    15061 ttaggattat ccttatactc cggaacgcat tgtttttgcg gaggctgggg agatgtagga
    15121 atcttgccgg tattttggtg ggttgttcgc taggttgcta tcgttctccc gtctgttgac
    15181 ggcggttctg ccagagatgt ccggaaccgc ttgatacggc actgttaacg gcacgttgct
    15241 agagttcaac ggccttcttg tctattgatg cgatggagcg gctgtaatgc gcctccgcaa
    15301 ttccagtgtg cggaccaaaa tcacggccct gctgctctcg ctgaccgcgt tgtgggtttt
    15361 cgccgcctgg gtcacgctcc gcgagggtgt gaacctccta tgggtcaacc agctcgacaa
    15421 ggggatcgcc cagccgggag acgtcctcat cgtcgacctc cagaaggagc gcctgctgtc
    15481 catggtgctc gccggcgacc ggacgcaggc gaacgccgac gccctgcgcg accagcggac
    15541 gagcaccgac cgcaagaggg cggcctacct gcgggacgcc cgttcgacca tgacgaagct
    15601 ggccgcggac gacgccctgg aggagctgct cgcgcagtcc ttcacggcgc tcgaggacct
    15661 ggacaaggcc cgcgcctggt tcgacgcccc cgacggcagg tcgcccgact gggcccgttc
    15721 gctctacacc gaggcgatcg gctcgatggg cctggtgtac gagggcctgg cgaccctcga
    15781 cgacgacgac ttcgccgcca ggacccggac cctggtcgag ctcaaccagt acaacgagct
    15841 gttctcccag gaggacgcgc tggtctccgg agtgctggtc gcagggcgct tcaccaacgc
    15901 ctcctacgcc gacttccacc ggttgctcgg cgtccagcgc cacgcgaggg ccgaagtgct
    15961 cgagaggctc gccgagttcg ccccggaaac ggtcgagagg cacgagaaga gcgagtccct
    16021 ggccacggtg acggccctgg aggaccgcct gctggcgatg atgggcaaca accatcgcaa
    16081 gcccatccag acggtctcct tcgccgcttg gaacaacgcc accaccgcct ggctggcgga
    16141 gtcgcaggac atcacgtggg acgccggcga ccagctcgtc gaggccgcca ccccgatcgc
    16201 gacgggagtc atcatccggc tggcgctggc cggcggtctg ggcttcctct ccgtcgtcgc
    16261 ctcggtgatc ctgtccgtca ccaccgcccg ccacctggtg cggcagctgg aacgcttgaa
    16321 ggacgccgcg cacgagctgt cggacgtgcg gctgccgaac gtcgtggagc ggctcggcca
    16381 cggcgagcag gtggacgtcg aggccgaggc gccgccgctg gagttcggcg acgacgacat
    16441 cggcaaggtg ggccaggcgt tcaacgcggt gcagaagacc gcgatccgca ccgcggtcga
    16501 gcaggccgag ctgcggcgcg gcatccgcga catcctgctg agcctcgcgc ggcgctccca
    16561 ggcgctggtg caccggcagc tgacgctgct ggaccagatg gagcgccggg agatcgacac
    16621 cgaggagctg gaggacctgt tccggctcga ccacctggcg acccggatgc ggcgcaacgc
    16681 cgagaacctc atcatcctct ccggcgcgac cccggcccgc ggctggcgcc ggcccgtccc
    16741 catggtcgac gtggtccgct cggccgtcgc cgaggtcgag gactacaccc gggtgaccgt
    16801 catgccgatc gacgaggtcc acctcgtcgg ccgtgccgtc gccgacatcg cccacctcct
    16861 ggcggagctg atcgagaacg cggtgtcgtt ctcgccgccg tacacctacg cgcagatctc
    16921 cggccacatg gtggcctccg gctacgccct ggagatcgag gaccgcggcc tgggcatgtc
    16981 ggacgagaac ctcgccgcca tcaacaggaa gatcgccgac ccgccggagt tcaacctctc
    17041 cagctcggtg cagctcggcc tctacgtggt cggcaagctc gccgagcggt acggcgtgca
    17101 ggtgacgctc aagcgttcgc cctacaaggg aacgaccgcg gtggtcatca tcccgcggga
    17161 actgctggag gaaggagagt ccggcgcgcc gtcgcagcag tctctgacgg tcgtcggggc
    17221 gaccatgccg gaagtcaccg actcgacgga cccccggagc ggggagcgct tcacgcccgt
    17281 cctggtcccg tcaccacccg aagaaacgcc gaccgccccg gcctccgcgc cgctgccggt
    17341 gcgggagaac ccgtccacgg ccggaccggc ctccgaggag accgagctca cgccctcggg
    17401 cctgccggtc cgcgttcccc aggccagcct cgccccgccg ctgcgggacg agccggtcgg
    17461 cgaggacgag ccggccggtg aggatcccgg ccgttcgccc gaggagatcc gcaggatcgt
    17521 gggagccttc cagagcggca ccctgcgcgg cagggcagcc tccgtcgaga gtgagaccga
    17581 gtgatgcaga agacaggagc aggcgccgac ctggcgtggt tgctcgatga cctggtcaag
    17641 cgggtcaacg aggcggaaca cgcgatcgtg ctgtccgcgg acggtctgct gatggcgcag
    17701 tcgcagggca tcggcaggga cgacgccgag cacctctcgg cggtcgccgc gggcatccag
    17761 agcctcgcca agggcgcggg cgagcggttc ggcggcggcg ccgtccgcca gaccatcatc
    17821 gagatgcggt cggccttcct gctggtcacc gtcgccgggc agggcgcctg cctggcggtg
    17881 ctcagcagcg aggacgccga cgtcggcctc atcgcctacg agatggccat gatggtcacc
    17941 aagctgggcc accatctctc caccccggca cgggtgacgg agtcggcgtg acctacccgc
    18001 ctcaggaacc tgagaacgag cgctggctgg acgagagcgc cggcccgttg gtcaggccgt
    18061 acgtgatgac gagcggccgg ctccagccgg tccgcggcga gttcgacctg atcaccctgg
    18121 tggaggcgac gggcccggct ccgtcggtgg cgatcggcct gggccccgag cacctggcga
    18181 tcatccgcct ctgccagacg ctgatgtcgg tggccgagat caccgcgcat ctggacctgc
    18241 cgaccggcac ggtgcgggtg ctgctgggag acctgctcga caagggcctc gtcaccgtcc
    18301 aggaacccca accggagatc gacatgcagg acctcaggat gtaccaggcg gtgatcgatg
    18361 gcctccgcgc cctctagcgc cgccgggacg cgccgccgga tgcccaccgc gatcaagatc
    18421 ctggtggcgg gcgggttcgg cgcgggcaag acgaccctgg tcggggcggt ctcggagacc
    18481 gagccgctgc gcaccgagga ggtgctcacc gaccgggggg tgggcgtcga cgacatcgag
    18541 ggcgtggaga ccaagcggac caccacggtg gcgatggact tcggccggat caccttcggc
    18601 gacgagttcg tcctctacct gttcggcacc cccggccagg agcgcttctg gttcatgtgg
    18661 gacgaggtgg cgctcggcgc gctcggcgcg gtggtgctgg ccgacacccg gcggctggcc
    18721 gactgcttcc cggcgatcga ctacttcgag cgccgcggca ccccgttcat cgtggcggtc
    18781 aactgcttcg agggggcgca gcggtacgag gcggacgagg tcaagcaggc gctgcagatc
    18841 ggtccgggca tcccggtgct gctgtgcgac gcccgcagga aggagtcctc caaggaggtg
    18901 ctcatcaccc tggtgcagca cgccatgaag atgagggcgg cccgctaggg ccgatcagcc
    18961 gcagccctcg aactgcggga cggtggtggt ggtcttcagc ccggtcggcc cgaaccactt
    19021 ggcgagcagc cgcgccgccg tcccgtcctg gtacatccgg gtgacggcgc ggttgaccgc
    19081 ctcgcacccg ctgacgtcgt ccttgcgcag gccgatgccg tacttctcgt cggtgaacct
    19141 ggcgttgacc atccggaagg cgccgggccg ccgcagggcg aagcccgcca ggatcaggtc
    19201 gtcggtggtg acggcgtcga gcccgccgtc gaggaggagc tggacgcact cgccgtacgt
    19261 cgccgcgtcg acgagttcgg cctcgatgcc cagctcctcc acgacccgct tccaggagtt
    19321 ggagccctcg ctcttgcaca gtttgcggcc cgccaggtcc cgcgggccga ggatgtccct
    19381 ttcgcccccg cggaccatga tgtcctggtg ggcgacgtag tagggcccgg cgaagttgac
    19441 cagggtcttg cgcagcgggg tgatggagta gctggccacc accaggtcga ccttccgccc
    19501 gatcaggaac tcctcgcgct gcccggaggt gagcccgacg aactccacgc gctcggcgcc
    19561 gagacgctcg gcgacgtagg aggcgacgtc cacgtcgaag cccaggaagg agccgtggga
    19621 ccgcaacccg atgcccggct ggtcgtactt caccccgatc cggagcacct tcctgccctc
    19681 cacccccggg gagcggtcgg cgccgcacgc gacggccagg gacagcagga ggacggtggc
    19741 caggaggagg gacaggaggc gtccgggcat gctggtggtc aacggtactc cgcgagtctg
    19801 ggccacacgc ccaggacgat gagcgcggcc aggacgatcc ccgccgcggg caggccccgg
    19861 ttccagccgt cgagggcggc ggcgccggcc gcgacctccc gttcgaagtc ggcgttgcgg
    19921 tgcgcgacga gccggctcag ctcctggtcg taggcggtga aggtctcggt catcaggccg
    19981 gtgcgcaggg cgatggcctc ccgctcgtcg ccgcggcgca ccaggccgcg catccgctcg
    20041 tcctgctcct ggaaggcccg gtagcggatg agcacctcgg acccctgcgg gacgccgccg
    20101 aggaacccca gctcgggcgg ggcctcggcg agccgccggt agtagtcggc gaggttgccg
    20161 gactcccggt aggcgatggc ctgggaggtg tcgaagtaga cctgggcgta ggtgtcggcg
    20221 cgccgcgggt cgagcaggaa gcgggtctgg tcggcggcgg cggtgttgct gatcgcgcgg
    20281 gcgcgggtga aggcgagggt ggggtcgaag ccctcctcct tggccatgcg caggtgcgag
    20341 gaggtgctgc ccagcacgag cagcgcccag ccccccagca ccagcgtgag cgcggtggcc
    20401 gcggccagcg ccgggctgag caggcgccgg aaccggtagg cgaggtagac ctggagcccg
    20461 gccagcaccg ccagcagcac cagcgcggtg acgccgacgg cgacgcggga gcgcaggacg
    20521 tgcgagcgct cgtcgacgta ggcgcgccgc acgacgctgg cgttctccag ggtgaggttg
    20581 taggccttgg gcaggatgtc ctggcgcatc aggtcggtgg cccgccggta gacccccagc
    20641 acgttctgcg gcggcggccc ggccggatgc ccggactggt cgttgaggag gagggcgcgg
    20701 gaggcgagct gctcgtacct gccgaggccg ttcagcacat cccggacggt gcggcggctc
    20761 gcccggtccg tcccggcgat ctcgtaggcc tgcagcagcg cccggtgggc ctcgccccgc
    20821 ctggcccggt accgctcctg ggcgcggtcg cggccggcgc cgaggtcgtg ctcggcgccg
    20881 atgagcagca gcccggcgag ctgggcgtcc atgtcgctga gcgcgaagta caggtggccg
    20941 gtgtgcacca cctgcggccc ggcgtcctcg ccgaccagcc gcaggccctg gcgggcgtcc
    21001 tccaggccgg tggagaccgc cgcgaccagg gcgatgacgg ccagcagcgc cgcggcggcc
    21061 cagccgcgca ggtggccggg caccgtccgg ggcagcgcgg agcgcccggc cgtccgccgg
    21121 agcgcccgga gcgccccggc caccttgctg atcacgacag ggactctctg cgcagctcga
    21181 gggtggtcca ggcgccgacg tggatgcggt cgccctcgtg gagcgggatc tcggcgccca
    21241 cggcgaccgg ggcgctgccg gcgttcagcc gggtgccgtt ggccgagccg gggtcgacca
    21301 ggcaccagcg gccgtcgcgg gagatcagga cggcgtgggt gcgcgagacc gcggggtcgc
    21361 gggtgggcac ggccaggtcg atgtcgggga cggtgccgcg cagcgtgctg cgccgcccca
    21421 gcagcacgcg gccgccggtg agggggctgc tgagccccgg cctgccctgc ggggccggca
    21481 gccggcccgc gtcgggtccg ctctcggcca ggatccgccg gtggtactcc ggatcggtgc
    21541 tgatcaccac gtaccagcgg gagcggaagt cctccggagc cgcgggcctg gggccgggca
    21601 cgccggtggc gaagtcgtgg ccgcagccct cgcagaagcg gccttcgccc ggcagcgcgc
    21661 actcggggca gggcccggag cgcgcggggg aggacgcggg cacgggaggc ggggcggggg
    21721 ccgcgccgcg gcgcagccgg aaggtgcagg tggtctcgtc gccctcgatg acgcggctga
    21781 gcatcgtggc cagcgggacg ttgccctggg cgcgggcgag ctggacggcg ctctccagct
    21841 cggcggcggc ggtgccggcg tccccggcct gctgggcggc caggcccgcc tggatgcgcg
    21901 cggccagttc gctctgcccg gtgtagtggg cgacgcgggc gtcgatccgg gtgcaccggg
    21961 tgcggtcgtc ggtccactcg gcgaacacgt cggcggcgcc cagcgcctcc ccgccgagca
    22021 ggaccgtgag ccgtgccgcg cgcatccgct ggccgacgtc ctggacgggc acccgcaggc
    22081 gcaggtggta ctcgcgggtc tcgcggcggc cccagcggcc ggtggagtgg tcgaaggagc
    22141 gcggggcgtc ctcgacggcg cgcgcggaga ggtcctcctc ggccggcagg acttgcttga
    22201 gggagcgcag gacgaccccg cgcggcaccg cgacccgcag gcgcacgtcc tcggcgggct
    22261 cgaaggggtc gcccgtcccg gtgacggaga tgatcgcgtg gaggtccgtc ccgccgtcgg
    22321 gcaggtagcg gttctggtcc acggacacgg tgaacggggt cctgatggtc atagttcgag
    22381 tccgtcccct tcgaccggga tgatcgcgac ggtgatgttg tcgtggccgc cgcccgacag
    22441 cgcggtgcgc accagctcgc gggcgaccga cagcggggtg cgccggccgc ggcgcccggt
    22501 gagcggcccg gagaccgggt cggccagcgg gtcggccagc gcggcggcca gcgccagcgg
    22561 cgaggccatg tagttccaca gcccgtcggt gcacaccacc agcacaccgg ggacctcggg
    22621 cgcgtagacc cgcacgtgca cgtcgatctc gcgggcgtcc gcgcccatcc agccgaccag
    22681 catgtgggcc ctgcggtcgg cgtaggcctc ctcccggctc atcatgccgt gcgcgatgac
    22741 gtgctcggcc caggagtcgt cctcggtgag cagctcgtca ccggtggcgc cgatccagta
    22801 ggcgcggctg tccccgatcc agccgatggt gatgacgggg cggccgtcca gctcgccggt
    22861 gaccgccgag acgtaggtgc aggcgggcgc cgaggagggg tcggcggcca ggcccgccac
    22921 ggccttggcg gcggccagcg cggcggtgcg ggtggcgtcg cgcgggtcgg cgccggcctc
    22981 cagctcccgg gtcaggacgg agatgccggt ctccaccgcg gtgccggagg cctcctcggg
    23041 ccggggggag gccgagacgc cgtcggagag caccgcggcc aggccgccgg ggatcgggga
    23101 cagcgccatg ccgtcctggt tggtgctgtg ccgcagcccc cggtcgctca ccgcggcggc
    23161 gtcgtcgccc aggtcgatct cccggtggtg gaccgtctcg gccgccggcc gcgccgcagg
    23221 gctcagccgg tggccgcagg cctcgcagaa caggtcgccg gcgaagaccg gggcggagca
    23281 ggaggggcag ggcatcggag tccgttcgct tcgggggttg gaacgtcaga acagggttct
    23341 gggacggatg gcgttggcca gggtgaccag ggcgtggcgc tcgccgggat cgtcggcgag
    23401 ccgggccagg gtgcggtagg cgcgttcgag accgcggcgg agctcctcct cgtcgagcgg
    23461 gacgcccagg acccgggcgt cggacgtacg gccggccagc acccagtcca gcgccgagcg
    23521 caggacctcg acggacagcc gggcgtggcg ttcggcgtcg aggcccagtc ggctgagacg
    23581 tctgctggca tcaatcagtt cacgttcaga cagatcccca ggttcccggc cgacggcgat
    23641 cgcgtggacc gcggcgacgc gggcgccggg gaagtggctg gaggacggcg ggacggagtc
    23701 gagcgcggcg atggcgccgg cccggtcccc ggccgccagg cgcacccggg acaggccgaa
    23761 ggcggcgctc acgtacgtct ggtcggtgcg ccacacggtc tggtagtggt gctcggcgtc
    23821 gggcaggcgg ccgagcagct cgtggcagaa gccgagggcg agcttgggcg cggcctcgcc
    23881 gggggcgagg tcgtacaggt cgtcgaaccg gtggcgcgcc tcgcgcagct ccccggcgcc
    23941 cagcgcggac accgcccggt accactcggc ccgccagtcc tcgcgtatcc cggccaggac
    24001 gcggcgggcc gccgcgtggt cgtcgagctc caggtgggcc agcgcccggt gcagccgcac
    24061 gtcgggggag tcggcggggg cggaggccag cgcggtgagc agggcgtgcg ggtcgccgac
    24121 ggtcagcgac gccaggaacc cggccgaggc gtccgaggcg cggggctgcg ggatgggcag
    24181 tgccagcagg gcgtcccggg gggtgagccg ttcggtgggg acgcgccggc cgggcccgaa
    24241 cagcgccgag ggcgcggggc gcggcctgcc gtcctgcgcg gagagcacct cgcgcagcac
    24301 cccggtgagc tgctcggcca tctcctgggc gtcctggaag cgggcgtagg ggtcgcgggc
    24361 ggtggcgcgg cgcaggaacc ggtcgtagga ctcgtgctcg cgcagcaccg ggacctgctc
    24421 gcggggcggc aggctcgcca cgtacttgcc ggtgtggccg tggaagggga agctgagcac
    24481 ggccagggcg cggccgacgg tgtacaggtc ggaggcgacg gaggggccca tcccgccgat
    24541 ctcgggcgcc tggtagccga ccgtcccgta gatcgcggac tcggtgtcgt ccatgcgccg
    24601 cacgccgccg aggtcgatga gcttgagctg ctcctcggac tggatggcgt tgtcgggctt
    24661 gaagtcgcag tacagcaggc ccaggccgtg caggtagccc atggcccgca gtacctccag
    24721 ggcgtaggcg atggcctggc cgagcggcag ggcggcgtcc tggccgtgct cgcgccggtg
    24781 ctcggccagg acgtccttga gcggatggcc gccgacgtac tccatgacga tgtagccgtg
    24841 gttgcgcagg gtgcgcgggt cggggtgctg gacgaagttg tagatccgca cgatgttggg
    24901 gtgctcgacc tcggccagga aggccttctc ggcggcggcg accgcgcccg cctcggggtc
    24961 ctcgctgtcc agcaggccct tgagcaccac ccagcggtcg ctgacgttgc ggtcgcgggc
    25021 caggtagatc cagccgaggc cgccgtgggt caggcagccg agca
//
