LOCUS       NZ_PVZV01000002        23182 bp    DNA     linear   CON 13-DEC-2024
DEFINITION  Actinocorallia populi strain A251 contig2, whole genome shotgun
            sequence.
ACCESSION   NZ_PVZV01000002
VERSION     NZ_PVZV01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinocorallia populi
  ORGANISM  Actinocorallia populi
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Thermomonosporaceae; Actinocorallia.
REFERENCE   1  (bases 1 to 1301122)
  AUTHORS   Li,X.
  TITLE     Actinocorallia populi sp. nov., an endophytic actinomycete isolated
            from a root of Populus adenopoda (Maxim.)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1301122)
  AUTHORS   Li,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2018) College of Light Industry, Textile and Food
            Engineering, Sichuan University, No. 24, First South Section First
            Ring Road, Chengdu, Sichuan 610065, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR MAR-2018
            Expected Final Version            :: yes
            Genome Coverage                   :: 221.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002995495.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 14:18:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,861
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,716
            CDSs (with protein)               :: 7,716
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 18 of 83
            Pseudo Genes (incomplete)         :: 70 of 83
            Pseudo Genes (internal stop)      :: 6 of 83
            Pseudo Genes (multiple problems)  :: 10 of 83
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:05:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 306841
            Orig. end                         :: 330023
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PVZV01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23182
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23182
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23182
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13182](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13182)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            91..615
                     /locus_tag="C2865_RS08385"
     CDS             91..615
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2865_RS08385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_106397791.1"
                     /transl_table=11
                     /translation="MARGGLALTGLALCGASGVLLGLNRFLGDRPVLGEGTSGFIARNP
                     WFWPAVAGLLTAVAVLGTCWLLIQGRTAALRRFSLLGGRRKALTNEAVAGLTREVLELP
                     GVHDVRVRFTGTRSRPRVMLQILCHESADLGLLLARISEDSLVRFREVIEMPDLHAVLR
                     FRLVYQETRIA"
     gene            879..1676
                     /locus_tag="C2865_RS08390"
     CDS             879..1676
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653883.1"
                     /locus_tag="C2865_RS08390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_106397792.1"
                     /transl_table=11
                     /translation="MGWESWWTGPLGFCAGLLIAVVTAPVGVSGAVFLLPVQLSVLGVP
                     SPAVTPTNLLFNVVAGPGALLRYRRSGQLAGPLARLLVAGTVPGVVAGAVIRVFALPGP
                     TVFRLLVAAFLLPLGSWLCLRTLRPSRRPAAPEPSRAALSALALGVGVVGGIYGVGGGS
                     LIGPILVGRGLPVAVVAPAALAATFITSIVGAATYALLSLLAPGDIAPVWSLGLLCGLG
                     GLIGGYLGARLQPRLPEKALRLLLGGLAVAVAGLYLVQGLGRG"
     regulatory      1824..1924
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            2121..3197
                     /gene="gcvT"
                     /locus_tag="C2865_RS08395"
     CDS             2121..3197
                     /EC_number="2.1.2.10"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004047 - aminomethyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /gene="gcvT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017610808.1"
                     /locus_tag="C2865_RS08395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="WP_232835459.1"
                     /transl_table=11
                     /translation="MKTTPLYELHQELGGNLVDFAGYLMPLRYRSETAEHQAVRTSAGI
                     FDVSHMGEIFVTGAQAAEALDHALVGKPSALEQGRARYTMLVDPEGGVLDDLIVYRLSR
                     HGFLVVANAANKGVVAAELTARAEGFEASVDDQSENYALIAVQGPRAQEILARLTDADL
                     AGLKYYSLVSGTVGGTVAFIGRTGYTGEDGFELFVDAGDAVGLWKKITEAGGDEITPCG
                     LSARDTLRLEAGMPLYGHELTAELTPYDAGLGRIVRLEKDFVGRDALAAVAESGPSRRL
                     VGLVARGRRVPRAGYAVIGDDGAPCGVVTSGAPSPTLGKPIAMAYVGTGAVPVAVDIRG
                     KHEPVDVVDLPFYRRTDK"
     gene            3194..3580
                     /gene="gcvH"
                     /locus_tag="C2865_RS08400"
     CDS             3194..3580
                     /GO_component="GO:0005960 - glycine cleavage complex
                     [Evidence IEA]"
                     /GO_process="GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /gene="gcvH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854160.1"
                     /locus_tag="C2865_RS08400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="WP_106397794.1"
                     /transl_table=11
                     /translation="MSVPEQLRYTEEHEWVSGLDGEDGVVTVGITDYAADALGDIVYVS
                     LPAEGDAVTAGEPCGEAESTKSVSDIYSPLSGEVVAVNQAVTEDPGTINADPYGEGWLY
                     RIRIGDDNPDLLDAEAYSKIIEEA"
     gene            3577..4836
                     /gene="glyA"
                     /locus_tag="C2865_RS08405"
     CDS             3577..4836
                     /EC_number="2.1.2.1"
                     /GO_function="GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0070905 - serine binding [Evidence IEA]"
                     /GO_process="GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (84-315). E-value:
                     1.4e-10. Score: 32.7. Matches aSDomain:
                     nrpspksdomains_C2865_RS08405_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="glyA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013151478.1"
                     /locus_tag="C2865_RS08405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine hydroxymethyltransferase"
                     /protein_id="WP_106397795.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.8e-09, bitscore:
                     32.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTLFQHLSEVDPEVHEAVRAELGRQQHTLEMIASENFAPVAVLE
                     AQGSVLTNKYAEGYPGRRYYGGCEYVDVTEQLAIDRAKALFGAEHANVQPHSGAQANTA
                     VYFALLDHGDTILGLDLAHGGHLTHGMRLNYSGKFLNVVPYHVRESDGRVDMDEVAALA
                     AEHRPKMIVAGWSAYPRQLDFARFREIADSVGALLFVDMAHFAGLVAAGLHPSPVPYAD
                     IVTTTTHKTLGGPRGGLILAREELGKKINSAVFPGMQGGPLEHVIAAKAVALKVAASEE
                     FKDRQRRTLQGARAIAARLLQDDAAKAGVKVLTGGTDVHLVLVDLVDSDLTGRDAEDRL
                     HEIGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFAEEDFEEVADIIALALQPSFDA
                     PALSARVKALADRHPLYPDL"
     aSDomain        3829..4521
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2865_RS08405_Aminotran_1_2.1"
                     /evalue="1.40E-10"
                     /label="C2865_RS08405_Aminotran_1_2.1"
                     /locus_tag="C2865_RS08405"
                     /protein_end="315"
                     /protein_start="84"
                     /score="32.7"
                     /tool="antismash"
                     /translation="LFGAEHANVQPHSGAQANTAVYFALLDHGDTILGLDLAHGGHLTH
                     GMRLNYSGKFLNVVPYHVRESDGRVDMDEVAALAAEHRPKMIVAGWSAYPRQLDFARFR
                     EIADSVGALLFVDMAHFAGLVAAGLHPSPVPYADIVTTTTHKTLGGPRGGLILAREELG
                     KKINSAVFPGMQGGPLEHVIAAKAVALKVAASEEFKDRQRRTLQGARAIAARLLQDDAA
                     KAGVKVLTG"
     gene            5326..6738
                     /locus_tag="C2865_RS08410"
     CDS             5326..6738
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013086.5"
                     /locus_tag="C2865_RS08410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_106397796.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.3e-08, bitscore:
                     28.4, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 4.4e-10, bitscore: 35.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLIVVGAGPGGLACAIAAAGAGADVLLLEKAGRIGGALPYSGG
                     HLSAAGFSAQREKGIEDDVAAHWADIRRISRGTGREDLTLLSLAEQPAVLEWLLDAGYA
                     IDPATPRIVHGHEQYGTPRTVHAPEPPGGPEILRVLELLLEPHVKSGKVDVRCGVKVAE
                     LLVETVGGEQAVVGVAAEDGRVFRAPSVVLATGGFGYNPELFAELDGAPLTTSAAPTST
                     GDGIEMGRRIGAGVQGRGKYIPTFGGLPPQGDDLRVDWRHRPHLVAPERPPWEIYVDRN
                     GRRWVAEDDPSIDLKERMLTAVDRMTFWMVFDARALRESRPMVHGWTPEELDARCGARR
                     GLHKAATLAELAAKAGISSDGLVGTVARYNAAVAAGRDDDFAREHLPAPIVEAPFYAIE
                     NHPVTLITFAGLDVDAELRVRRGDGTVIPGLYAVGEVIGSAAVNGNSFCSGMCLTPAMA
                     FGRIVGRALSGA"
     gene            complement(6769..7587)
                     /locus_tag="C2865_RS08415"
     CDS             complement(6769..7587)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013530.5"
                     /locus_tag="C2865_RS08415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_157963626.1"
                     /transl_table=11
                     /translation="MHYVIIGCGNVGMELARRWTEAGHRVTGTTTTEGRVAELLEVCSD
                     AVVLRGSDRGAVEKATEGADAVVLTVSPRLSRSFDAESRIAEYADTLTASAVTAAAVHP
                     RVVFTSSISVYGAGRGELVDEATPPTDDGDASPRNFASGEAAVLATPRGAVVRIPDVHG
                     HPRDIDYPARVRMAHEMLGGSVPFSAEALLYRIDYRDAAAALDFVVGRELTGVYNAIPD
                     GTVPPTNAELFGEICAAEGLPPLTFRGEIKTPVMPVSSARLRAAGFSFAH"
     gene            complement(7995..8777)
                     /locus_tag="C2865_RS08420"
     CDS             complement(7995..8777)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019629871.1"
                     /locus_tag="C2865_RS08420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_106397798.1"
                     /transl_table=11
                     /translation="MAVKARGVLYPVEQSRYVELTHHAPSAPLEPYVEHYWHVRWAVDG
                     VFETKVLSHPNVHLGMEPEGVFVYGVHRGLFTRRLEGRDHTLGVKFRVGAFRAFCGAPV
                     SALADHRVPAAGYFGPEADALGRTVQATADPAEAAALAEAFLLPRVPARPDPDALRAAG
                     LVARFTTEPSLFRVSDAAASAGLSVRALQRLFSEYVGASPKWVLRRARLHEVAARADAA
                     EPIDWPALATELGYADQSHLIRDFTASVGHSPTRYTRP"
     misc_feature    8834..8849
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.17"
                     /tool="antismash"
     misc_feature    complement(8842..8858)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.69"
                     /tool="antismash"
     gene            8842..9423
                     /locus_tag="C2865_RS08425"
     CDS             8842..9423
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019629872.1"
                     /locus_tag="C2865_RS08425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_106397799.1"
                     /transl_table=11
                     /translation="MNETYKAMTECAAEAVRVAGKVRGELLDGPTTCAEFDLRALVNHW
                     VLYTSYGLERRALKQPLPEELVARDFTAEDGWAAAYAAQLDRALQAWADPAAWEGEIPL
                     GDGRTGAAPQIAALIVKEMAVHGWDVARSIGEDFAISDDSAAVVLHVVEENAELYRQYQ
                     GFAAPVEVPASAPLFTRALALSGRDPHQTV"
     gene            complement(10001..11008)
                     /locus_tag="C2865_RS08430"
     CDS             complement(10001..11008)
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630110.1"
                     /locus_tag="C2865_RS08430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_106397800.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.3e-61, bitscore:
                     202.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALHEVSRPAAEVLEWGRSLVEPALREAVGSLPDGVRLITGYHL
                     GWWDAEGNPTGSSGKALRPTLALLAARAVGGRAEDAVPAAVAVELIHDFSLLHDDVMDG
                     DETRRHRPAAWRVFGTNPAILTGDVLLTLAVETLAASGGPTRVLTTAVLDLLHGQNLDM
                     SFETRGDVLLSECISMAVGKTGALMRCACALGAGAGGGTPDQVAAFALFGEHLGLAFQH
                     MDDLLGIWGDPAETGKPVYSDLLNRKKSLPVVAALTSGTPEADALRALYRSPAPFDPAE
                     AAALIEAAGGRSWSHDRLTQLRNQALATLDPVSPAPHPLAELTALADLVITRAR"
     gene            complement(11005..13182)
                     /locus_tag="C2865_RS08435"
     CDS             complement(11005..13182)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012886878.1"
                     /locus_tag="C2865_RS08435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="terpene synthase family protein"
                     /protein_id="WP_106398630.1"
                     /sec_met_domain="T1TS (E-value: 4.8e-76, bitscore: 253.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPFQLPEFYLPYPARLNPAVESAREHARQWAYEMGVLGPGSVWT
                     EEEYAAHDYATLCAYTHPDSPGPVLDTVTDWYVWVFYFDDHFLELFKRTHDLAGAQRYL
                     DRLPLFMPADPAAGTPEPEHPVERGLADLWARTVPAMSPRWRERFAANTAALLDESLWE
                     LVNIEAGRIANPIEYVEMRRRVGGAPWSSDLVEYATGCEVPDGIARSRPVNVLRDSFAD
                     AVHLRNDLFSYQREVQDEGELSNAVLVFQEFFGHDAQTAAELVNELLSSRLYQFDHTAV
                     TELPVLLEEHAVPPEGRLAVAGWVKGLQDWQAGGHEWHMRSSRYMNQGAPRYSPSGLGT
                     SAARLVPTPQNLGFGRLRAYRHVPFRRVGPSLLPEFDLPYRLRLSPHLDHARRENNAWA
                     HRMGFDTPGALWTERQLHGFDFPLCSAGLDPDATAHELVLSSGWLTWGTYIDDWFPRVH
                     GAARDAAGARAFARRLPAFMPVDLGPVPPPLNPVEAGLADLWARTAGPMSDRQRQGFHR
                     AIAVMIEGMAWEVAGAAQHRLPDPVDYVEMRRLTFGSDLTMFLSRIGYEKQIPEDVFAS
                     RTLQSINNAAADCGTFLNDLFSYQKEIEFEGELHNIVLILEHFLGVSKERAVEFTGRLM
                     NLRRRQFEHLIAVELPVLCDRLGLSAEARSALDAYLDELRDWMVAILNWHRDTSRYPEA
                     ELVRDLPSPHGLPALTGLGMAAARLFAERTS"
     gene            complement(13217..14626)
                     /locus_tag="C2865_RS08440"
     CDS             complement(13217..14626)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017619264.1"
                     /locus_tag="C2865_RS08440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_106397801.1"
                     /transl_table=11
                     /translation="MTETADRAQANGSSQAEQLSLGTAAARNLASTTKTPPQMQEITSR
                     WLLKMLPWVQVSGGGYRVNRRLTYTLGDGRIEFLSTGAQVQVIPEELAELPVLRDFDDP
                     EVLRTLANRCEQRELAPGEVLAEAGTPAEYVVLLAHGKLQKIGLSKYGEEVSLGLCADG
                     DFLGADALVGEHEWEYTLKAQTSCTVLTLSRADFRQVRGSSPVLQAQVAAYLASPVPEH
                     NRHGEKEIALAAGHAGEPVLPGTFVDYELEPREYELSVAQTVLRVHTRVADLFNEPMNQ
                     VEQQLRLTIEALRERQEHEMINNREFGLLHNADLRQRIQTHSGPPTPDDLDELLSRRRG
                     SKFFLAHPKAIAAFGRECNKRGLYPTPVDVGGHHIPAWRGVPIFPCNKIPVTGQQTSSI
                     LVMRTGEEDQGVVGLHQTGIPDEYQPSLSVRFMGITEQAVIQYLVSAYYSCAVLVPDAL
                     GVLENVEIGHF"
     misc_feature    complement(14676..14693)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.77"
                     /tool="antismash"
     gene            complement(14745..15647)
                     /locus_tag="C2865_RS39925"
     CDS             complement(14745..15647)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2865_RS39925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_198653094.1"
                     /transl_table=11
                     /translation="MMIKRFAALGGVLCALTALGPSVSAEPEPGVVICVGADLVLVQLD
                     VTIVIGAGQCATPPAPEPPAPEPPAPEPPAPEPPAPEPPAPEPPAPEPEPPAPEPEPPA
                     PEPEPPAPEPVPLPPAPPAPEPAPVPPAPEPVPVLPEPEPPAPEPEPVPVPPEPVPVPP
                     EPAPPAPAQPEPAPPAPPPAPVPPVAEPPAAVPPEAGPPVAAPPAVVPPVAVPAMPSAT
                     GATPRPRSAAPEAGPPSARPSPTPRRSVRPAGQEAVARPAVRRFRPLHEERNVFGGVLA
                     AAVVSVVVSAACGAIFRPR"
     gene            complement(15644..16369)
                     /locus_tag="C2865_RS08450"
     CDS             complement(15644..16369)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2865_RS08450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="DUF4239 domain-containing protein"
                     /protein_id="WP_106397802.1"
                     /transl_table=11
                     /translation="MFSRPKRRSDRSERPDRSPDTEPDGPTSSHAGAMFSALFLLVFAI
                     AIIVPWTVADSARQNTYAEAQALTEAYWNAGDLPADSAMATREALREYTRFVTEREWRL
                     LARGELAEAGWARLNSLRADLGMLEPRSKDEKDSLAAVEAQLEQVYAARRQRAVDAQAS
                     LPPGVLWLTVLTAGLVLAFPLLAGARPRGPVRFTYLLLAGSVAVGVYLVFAINHTFTGP
                     LGVDASAFESAWREFRQIP"
     gene            complement(16456..17778)
                     /locus_tag="C2865_RS08455"
     CDS             complement(16456..17778)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854156.1"
                     /locus_tag="C2865_RS08455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RIP metalloprotease"
                     /protein_id="WP_198653096.1"
                     /sec_met_domain="Peptidase_M50 (E-value: 5.2e-51, bitscore:
                     169.5, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METLIVLGGALLFFVLLMASIAFHELGHLSFAKRFGVRTPQYMVG
                     FGPTLKSWRRGETEYGIKWIPLGGYIRMIGMLPPRKGDPEGMVRASSTGRFQMLIDSAR
                     EGALEEVGPGDADRVFYSKKWWQKLLIMFAGPAANLLLAVVFFAVLIMGLGTLQSTPTI
                     SSVSKCVIPAEQAYLPDGSPRECTPEETARSTPAAKAGLRPGDTFVSFGGQRIEDYSQL
                     QGLIRDSANRTVPAVVRRDGKEVPVSLQITANQMQDLKDSDKVVTVGFLGISPLIDRVQ
                     GGPADVATQMGDMTTRTLEAFVQLPQKMVGVWHAAFSGEERDPEGPIGVVGASRLGGEI
                     LASENPGVEKLSWFLALLASINFAVGMFNLIPLLPLDGGHIAGALWEGVKRGVARLLRR
                     PDPGYVDVAKLLPLTYAMSLVLLVMGALLVYADIFNPVRLT"
     misc_feature    complement(17771..17786)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 24.05"
                     /tool="antismash"
     misc_feature    complement(17917..17933)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     misc_feature    complement(17918..17932)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            17946..19019
                     /locus_tag="C2865_RS08460"
     CDS             17946..19019
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630030.1"
                     /locus_tag="C2865_RS08460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="WP_106397803.1"
                     /sec_met_domain="PALP (E-value: 2e-50, bitscore: 168.1,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSTDRCEPAGRAWIAEAIRRVEADNNRSADTHLHVFPLPPEWGI
                     DLYLKDESVHPTGSLKHRLARSLFLYALSSGWITEGTTVIEASSGSTAVSEAYFARLLG
                     LPFVAVMPRSTSPEKIALIEFQGGRCHFVDDPASIYAEAGRLAERTGGHYLDQFTYAER
                     ATDWRANNNIAASIFEQLALEPHPEPAWIVVSAGTGGTAATIGRYVRYRRHQTRLAVVD
                     PEGSAFYDSWVSGDTALTAPGSRIEGIGRPRVEPSFLPSVIDRMYRVPDAASIACMRWT
                     SEVTGRSVGGSTGTNVWGALQVIGEMRERGEQGSVVTLICDGGERYTHTYLSDAWLAGQ
                     GLDLAPYLAELRALLNP"
     gene            19101..20390
                     /locus_tag="C2865_RS08465"
     CDS             19101..20390
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132763.1"
                     /locus_tag="C2865_RS08465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RIP metalloprotease"
                     /protein_id="WP_232835460.1"
                     /sec_met_domain="Peptidase_M50 (E-value: 2.7e-45, bitscore:
                     150.8, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLALGVVLFFLLLMASIALHELGHLLVAKRFGVRCPQYMVGFGPT
                     VRSWRRGETEYGFKWVPFGGYVRMIGMLPPRAGDPEGRLRRSSTGRFGQLIDSARKESL
                     EEVGPDDADRVFYAKKWWQKALISFAGPLMNFFLAFVLLGIALVGFGIKEPTMGVATVA
                     KCVVPAAQAARGCGPDDPPTPAARSGLRPGDEIVSFDGVPVTRYRQFQQLVRDSAGRQV
                     RLEVRRDGRELVLTPTLIANRVAALDGRSGTVTAGFLGITPVQEYVRQDPLDVLALMGD
                     MAGRTLEAFAVLPQKMAGVWDASFRGAERESDSPVGVVGASRIGGEVLAADTRAADKIV
                     LFLLVLGSLNFGLAAFNLIPLLPLDGGNIAGSLWEGLKRAFARVAGRPAPGPVDVAKAL
                     PLTYVVGALLLAMGLLIAYADLVNPIRLRG"
     gene            complement(20398..21906)
                     /locus_tag="C2865_RS08470"
     CDS             complement(20398..21906)
                     /EC_number="6.5.1.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003910 - DNA ligase (ATP) activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0071897 - DNA biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630031.1"
                     /locus_tag="C2865_RS08470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-dependent DNA ligase"
                     /protein_id="WP_106397804.1"
                     /transl_table=11
                     /translation="MLLAELAAAWRAVSETSARREKTALIAACLRDAGPEEAPLVVHYL
                     AGELPQRQIGIGPSALGDRPTASPSPGLSVSRVDAVFSEIKAASGPGSVAGKRRLLRAL
                     LAEATGPEQEFLVRLLAGDLRQGALEGVMTEAIAKAAGIPAAAVRRAVMLRGSLSAVAV
                     AALSGGAEALSAFTLRVGRPVRPMLASSAPSLEEALKGEMALEWKMDGIRAQLHVEGEQ
                     VRVFTRTLEEITSRVPEVVERVRALGLRSAILDGELIALREDGRPHPFQVTSARAATRS
                     GGIGGLSLFAFDVLHLDGVDLLDEPGSVRGEALVRALPEPLRMPRTVTAELPEAEAFLA
                     GALARGHEGVLLKSLGTPYTAGRRGAGWIKVKPRHTLDLVVLAVERGSGRRRGTLSNLH
                     LGARDPRTGGFVMLGKTFKGLTDRMLAWQTERFTGLKTADDGWTVTVRPVQVVEIAFDG
                     LQRSPRYPGGLALRFARVLRYRSDKTAEEADTIDTVRALAGFEP"
     gene            21965..22762
                     /locus_tag="C2865_RS08475"
     CDS             21965..22762
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2865_RS08475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157963627.1"
                     /transl_table=11
                     /translation="MRADFDRVYSPPEPPEPSHWRPRGWQVAFISFLLAAGGVFFAVPL
                     LLDDSPEDGAMPTLTAEHENATEPPPDSPPESAAPEPEPSRPAEPSPAPSAPAGEGPLT
                     ELPKKVCDSVSEATFLKLVPKGEPEEYGGSRAGSCGYTSDGADDFRYLRLETRLADVTG
                     DMDPITSAKWSFGQDYKMQEEDKITDTLLLEKVPGLGEEAFRRVYTEDGVANVTTARIA
                     VRVQNLIVTGTYSRAFEKKPQEQQDACLEGALEVVKEALRSYT"
     misc_feature    21978..21991
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(22769..22784)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     misc_feature    22860..22877
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.25"
                     /tool="antismash"
ORIGIN
        1 cccgctgcgc cgggcggtgc tcgcccggct ggaggagatc ggcccgcagc gccgccgcgc
       61 ggtcgccgtc cggctgggcc gggggggctg atggcgcgcg gaggactggc gctgacgggg
      121 ctggcgctgt gcggggcgag cggggtgctg ctggggctca accggttcct gggcgaccgg
      181 cccgtgctgg gcgagggcac ctccggtttc atcgcccgca acccctggtt ctggccggcg
      241 gtggcgggcc tgctgaccgc ggtggcggtg ctggggacgt gctggctgct gatccagggg
      301 cggacggcgg cgctgcgccg tttcagcctg ctgggagggc gccgcaaggc gctgacgaac
      361 gaggcggtgg ccgggctcac ccgcgaggtg ctggagctgc cgggcgtgca cgacgtgcgc
      421 gtgcgcttca ccggcacgcg ctcccggccg cgggtgatgc tgcagatcct ctgccacgag
      481 agcgccgacc tcgggctgct gctcgcccgg atcagcgagg actcgctggt gcgcttccgc
      541 gaggtgatcg agatgcccga cctgcacgcc gtcctgcggt tccggctggt ctaccaggag
      601 acgcgcatcg cttaaagagt gctctaccag tatttgtcgg ttctgatggc gagacgtccc
      661 gtccggcttc atacagttct aagcaagtcg actcctcgtc catgtgcagg gggtggatat
      721 cgatctgcag tggcaacggc atcatgttcc gcacccgggt aggggaaggg gtctacgagg
      781 gattgagaca acagagctag accttctgct cgagaccggc ggcgcccagg gcgccgccgg
      841 tctccatgtc cgcgggtatt ttatgcaatc ctggtctaat gggttgggaa tcgtggtgga
      901 ccgggccgct cgggttctgc gccgggctgc tgatcgcggt ggtgaccgcg cccgtgggcg
      961 tgtccggggc ggtgttcctc ctgccggtcc agctgagcgt gctcggcgtg cccagccccg
     1021 ccgtcacccc caccaacctg ctgttcaacg tggtggcggg ccccggcgcg ctgctcaggt
     1081 accgcaggag cgggcagctg gccggccccc tggcgcggct gctggtggcc ggtacggtcc
     1141 ccggcgtggt ggcaggcgcg gtgatcaggg tcttcgccct tccgggcccg acggtgttcc
     1201 ggctgctggt ggcggccttc ctgctcccgc tggggtcgtg gttgtgcctg cggacgctgc
     1261 gcccgtcccg ccgccccgcg gcgcccgaac cgtcccgcgc cgcgctgtcc gcgctggccc
     1321 tgggcgtcgg cgtcgtcggc gggatctacg gtgtcggcgg cggctccctg atcggcccga
     1381 tcctcgtggg ccgcggcctg cccgtcgcgg tggtggcgcc cgcggccctg gccgccacct
     1441 tcatcacctc gatcgtggga gcggccacct acgccctcct gtccctgctc gcccccggcg
     1501 acatcgcccc cgtctggagc ctgggcctcc tgtgcgggct gggcggcctg atcggcggct
     1561 acctgggcgc ccgcctccag ccccgcctcc cggagaaggc gctgcggctg ctgctcggcg
     1621 gcctggccgt cgccgtggcg ggcctctacc tcgtacaggg gctgggccgg ggatgagccg
     1681 ggacaccgca cgccctccca ggccccggcc ctcggaagcg gatgcggagc cgggcggagg
     1741 cctcccggcg gcgggggagg ggcgaagggc atcctggcgc ggccggggcg ggcggggagc
     1801 cctatagtgg tggcgacgcc gaatgatccc gtgcgggaga gcgtccggac cccggcgggt
     1861 ccgggccacc gaaggagcaa ttcctccccg gaacctctca ggtaaccagg accgcagggg
     1921 tgggcggcct ctggaaagag aaggccccga gccttccgcc gaaggtgaaa gcccgtacgg
     1981 gtgaagctct caggcagacg agacagaggg ggagggcccg actcggcagg tgtacggatg
     2041 ggacgatggg aaacgttctg ccgtgtgccg gtaacaagga gctcacccag gtgtccactg
     2101 cctccgaaaa gtctgcttcc gtgaagacga cgccgctgta cgagctgcac caggagctcg
     2161 gcggcaacct cgtcgacttc gccggatacc tcatgcccct gcgctaccgc tcggagaccg
     2221 ccgagcacca ggccgtgcgg acctccgccg ggatcttcga cgtctcgcac atgggtgaga
     2281 tcttcgttac aggcgcgcag gccgccgagg cgctggacca cgcgctggtc ggcaagccct
     2341 cggcgctgga gcaggggcgc gcccgctaca cgatgctcgt cgaccccgag ggcggggtgc
     2401 tggacgacct gatcgtctac cggctcagcc ggcacgggtt cctggtggtg gccaacgccg
     2461 ccaacaaggg cgtggtcgcg gccgagctga cggcgcgggc cgagggcttc gaggcgtcgg
     2521 tggacgacca gtccgagaac tacgcgctga tcgccgtcca ggggcccagg gcgcaggaga
     2581 tcctggcgcg gctgaccgac gccgacctgg ccgggctgaa gtactactcc ctggtcagcg
     2641 gcacggtggg cggcaccgtc gccttcatcg gccgcaccgg ctacaccggt gaggacggct
     2701 tcgagctgtt cgtcgacgcc ggggacgccg tcgggctctg gaagaagatc accgaggccg
     2761 gcggcgacga gatcaccccg tgcggcctgt cggcgcgcga caccctgcgc ctcgaggcgg
     2821 gcatgccgct gtacgggcat gagctgacgg ccgagctgac cccgtacgat gctggtctcg
     2881 gccggatcgt acggctggag aaggacttcg tcggacgcga cgccctggcg gccgtcgccg
     2941 agagcggacc gtcccgcagg ctcgtcgggc tcgtcgcgcg cgggcggcgg gtgccgcgcg
     3001 cgggatacgc ggtcatcggc gacgacggcg cgccgtgcgg cgtcgtgacc agcggagcgc
     3061 cctccccgac cctgggcaag cccatcgcca tggcctacgt cgggaccggc gccgtgccgg
     3121 tcgccgtcga catccgcgga aagcacgaac cggtcgacgt ggtcgacctg cccttctaca
     3181 ggagaacaga caagtgagcg ttcctgagca gctccgctac accgaggagc acgaatgggt
     3241 gtcgggcctg gacggtgagg acggcgtcgt gaccgtcggc atcaccgact acgccgccga
     3301 cgccctcggc gacatcgtgt acgtctcgct gcccgcggag ggggacgcgg tgaccgcggg
     3361 cgagccctgc ggcgaggccg agtccaccaa gtcggtctcc gacatctact cgccgctgtc
     3421 cggcgaggtc gtggcggtca accaggcggt caccgaggac cccggcacga tcaacgccga
     3481 cccgtacggc gagggctggc tctaccggat ccggatcggc gacgacaacc cggacctgct
     3541 cgacgccgag gcctactcca agatcatcga ggaagcatga gcaccctttt ccagcacctt
     3601 tccgaggtcg accccgaagt ccacgaggcg gtccgcgccg agctggggcg ccagcagcac
     3661 accctggaga tgatcgcctc ggagaacttc gccccggtgg cggtgctcga ggcgcagggc
     3721 tcggtgctga ccaacaagta cgccgagggc tacccgggcc ggcgctacta cggcggctgc
     3781 gagtacgtgg acgtcaccga gcagctggcg atcgaccggg ccaaggcgct gttcggcgcc
     3841 gagcacgcca acgtccagcc gcactcgggc gcgcaggcca acaccgcggt gtacttcgcg
     3901 ctgctcgacc acggcgacac catcctcggc ctcgacctgg cgcacggcgg gcacctgacc
     3961 cacggcatgc ggctgaacta ctccggcaag ttcctgaacg tggtgcccta ccacgtccgg
     4021 gagtccgacg gccgggtgga catggacgag gtcgcggcac tggcggccga gcaccggccc
     4081 aagatgatcg tcgcgggctg gtcggcctac ccgcggcagc tggacttcgc gcggttccgc
     4141 gagatcgccg actcggtggg cgcgctgctc ttcgtggaca tggcgcactt cgcgggcctg
     4201 gtggccgccg ggctgcaccc gtcgccggtg ccctacgccg acatcgtcac gaccaccacg
     4261 cacaagacgc tgggcgggcc gcgcggcggc ctgatcctgg cccgcgagga gctcggcaag
     4321 aagatcaact ccgcggtctt ccccggcatg cagggcggcc cgctggagca cgtgatcgcg
     4381 gccaaggccg tggcgctcaa ggtggcggcg tccgaggagt tcaaggaccg ccagcggcgc
     4441 accctgcagg gcgcgcgggc catcgccgcc cgcctgctcc aggacgacgc cgccaaggcc
     4501 ggcgtgaagg tgctgaccgg cggcacggac gtgcacctgg tcctggtcga cctggtggac
     4561 tccgacctga ccggccggga cgccgaggac cgcctgcacg agatcggcat cacggtcaac
     4621 cgcaacgccg tccccaacga cccccgcccg ccgatggtca cctccggcct gcgcatcggc
     4681 accccggccc tggccacccg cgggttcgcc gaggaggact tcgaggaggt ggccgacatc
     4741 atcgccctcg ccctccagcc ctccttcgac gccccggccc tgtccgcccg cgtcaaggcg
     4801 ctggccgaca ggcacccgct ctacccggac ctgtgacggc cctccggacc ccggacccgg
     4861 caccctgatc cgcccgcgag gccccgcccg acttctccgg gcggggcctc gtgccgtccc
     4921 ggcgcaccgc cgccgcccgc ggcgtgcggt gggggctgtt tcggtgtgct gctgtttgtt
     4981 ctcttcggtt ctggtgggtc gccggttcgg agttagccgg tcgtgctgcg ggggctgttt
     5041 cagtgcgctg ccgtctgttc tcttcggctg cggcgggttg ccgggctcgg ggttggctgg
     5101 tcgtgctgtg ggggctgttt cggcgtgctg ccgcccgttc tctcgggctc cggcggatgc
     5161 ggctgcgggc ggggtttcac gctgcttcgg tgtgcggtct ctgtgcggcg ggagccgttc
     5221 cgtccggtcc ggcgggggtc acgggccggg ggtttcttga ccggggaggc cggtggggaa
     5281 acactgtatc cgctgaggga acgtgatggc gggtgcggag gcgcgatggt gaagctgatc
     5341 gtggtggggg cggggcccgg agggctggcg tgcgcgatcg ccgcggcggg ggcgggagcg
     5401 gacgtgctgc tgctggagaa ggccgggcgg atcggcgggg cgctgcccta ctccggcggg
     5461 cacctgtcgg ccgcggggtt ctcggcgcag cgggagaagg gcatcgagga cgacgtcgcc
     5521 gcgcactggg ccgacatccg gcgcatcagc cggggcaccg ggcgggagga cctcaccctg
     5581 ctgtcgctgg ccgaacagcc cgcggtgctg gagtggctgc tggacgccgg gtacgccatc
     5641 gacccggcca ccccgcggat cgtgcacgga cacgagcagt acggcacgcc ccgcacggtg
     5701 cacgcgcccg aaccgccggg cgggccggag atcctgcggg tgctggaact gctgctggaa
     5761 ccgcacgtga agtccgggaa agtggacgtc cgctgcgggg tcaaggtcgc ggaactgctc
     5821 gtcgagacgg tcggaggcga gcaggccgtc gtcggtgtgg cggccgagga cgggcgggtc
     5881 ttccgggcgc cctcggtggt gctggcgacc ggcgggttcg ggtacaaccc cgagctgttc
     5941 gccgaactgg acggggcgcc gctgacgacg tccgccgcgc cgacgtccac cggcgacggc
     6001 atcgagatgg ggcggcggat cggcgcgggc gtccaggggc gcggcaagta catccccacc
     6061 ttcggcgggc tgccgcccca gggcgacgac ctgcgcgtgg actggcggca ccggccgcac
     6121 ctggtggcac cggaacggcc gccgtgggag atctacgtcg accggaacgg gcggcgctgg
     6181 gtcgccgagg acgacccgag catcgacctg aaggagcgga tgctcaccgc cgtcgaccgg
     6241 atgaccttct ggatggtctt cgacgcccgc gcgctgcgcg agtcccggcc gatggtgcac
     6301 ggctggaccc ccgaggagct cgacgcccgg tgcggagcgc gccgcggcct ccacaaggcc
     6361 gcgaccctcg cggagctcgc cgcgaaggcg ggcatctcct ctgacggcct ggtcgggacc
     6421 gtggcgcgct acaacgcggc ggtggccgcc ggccgcgacg acgacttcgc ccgcgagcac
     6481 ctgcccgccc cgatcgtcga ggcccccttc tacgccatcg agaaccaccc cgtcaccctg
     6541 atcacctttg cggggctcga cgtggacgcc gagctccgcg tccgccgggg ggacggcacc
     6601 gtcatccccg gcctgtacgc cgtcggcgag gtcatcggct ccgcagccgt gaacggcaac
     6661 tcgttctgct ccggcatgtg cctcaccccc gccatggcct tcggccgcat cgtcggccgc
     6721 gccctgtccg gcgcctgagc accgccgggg cgccggactc ggcggtgctc agtgggcgaa
     6781 ggagaagccg gcggcgcgga gcctggccga ggagaccggc atgacgggcg tcttgatctc
     6841 gccgcggaag gtcagcgggg gcaggccctc ggcggcgcag atctcgccga acagctcggc
     6901 gttggtcggc gggacggtcc cgtcggggat ggcgttgtag acgccggtga gctcccggcc
     6961 gacgacgaag tccagcgcgg ccgcggcgtc gcggtagtcg atgcggtaca gcagcgcctc
     7021 ggccgagaac gggacgctgc cgcccagcat ctcgtgcgcc atccgcaccc gggccgggta
     7081 gtcgatgtcg cggggatgcc cgtgcacgtc cgggatgcgc acgacggcac cgcgcggcgt
     7141 ggccagcacg gccgcctctc ccgaggcgaa gttccggggc gaggcgtccc cgtcgtcggt
     7201 cggcggcgtc gcctcgtcca ccagctcgcc ccgccccgcc ccgtagacgg agatcgaact
     7261 ggtgaacacc acccgcgggt gcaccgcggc cgccgtgacc gcgctggccg tgagcgtgtc
     7321 ggcgtactcg gcgatccgcg actcggcgtc gaacgaccgc gagagccgcg gactcaccgt
     7381 caacacgacc gcgtccgccc cctccgtcgc cttctcgacg gcaccccggt cgctgccccg
     7441 cagcaccacg gcatcggagc agacctccag aagctccgcc acccgcccct cggtcgtggt
     7501 cgtcccggtc acccgatgcc ccgcctccgt ccagcgccgg gccagctcca tcccgacatt
     7561 gccgcaaccg atgatcacat aatgcacgcc gaagacctct ctttggaaac accgtttcca
     7621 tactgtccca tcccccaccc cctgccaaga ccactcgcac ccccacccgc cccgcccctc
     7681 cgcgaacgga cggacacgcc ccccgcctag gcggcacgaa cctccgcccg acgggcaccg
     7741 cgagcccccg cagccccgcc gtcccaacga ggcggcgaga gaggcggcac cgcccacggc
     7801 cccggtcggc ggccgagacc gcgccgtccg ctgctcccgg agcgcgagtt ccttacggtt
     7861 cgtcggcccg gccgggcgac gggaacgacg tcgtccgcgg tcggtcgggc agcggttgaa
     7921 gcgagcggtt cgcaggctcg gcggggtggt ggggagcggc gtggttcgtc ggcgtggcgg
     7981 gaggcgggtg ggggtcaggg gcgggtgtag cgggtggggg agtggcctac ggaggcggtg
     8041 aagtcgcgga tgaggtggga ctggtcggcg tagccgagtt cggtggcgag ggcgggccag
     8101 tcgatgggct cggcggcgtc ggcgcgggcg gcgacctcgt ggaggcgggc ccggcggagg
     8161 acccacttgg gagaggcgcc gacgtattcg gagaagaggc gctggagggc gcggacggac
     8221 aggccggcgg aggcggcggc gtcggagacg cggaagaggg acggctcggt ggtgaagcgg
     8281 gcgacgaggc cggcggcgcg cagggcgtcc gggtcggggc gcgcggggac gcgggggagg
     8341 aggaaggcct cggcgagggc cgccgcctcg gcggggtcgg cggtggcctg gaccgtgcgg
     8401 cccagggcgt cggcctcggg gccgaagtac ccggcggcgg ggacgcggtg gtcggcgagc
     8461 gcggagacgg gggcgccgca gaaggcgcgg aacgccccga cgcggaactt cacgcccaag
     8521 gtgtggtcgc ggccctccag cctgcgggtg aacaggccgc ggtggacgcc gtagacgaac
     8581 acgccctcgg gctccatgcc caggtgcacg ttcgggtggc tgaggacctt ggtctcgaag
     8641 accccgtcga ccgcccagcg gacgtgccag tagtgctcga cgtacggctc gaggggagcg
     8701 ctgggcgcgt ggtgcgtcag ctcgacgtaa cgggactgtt cgacggggta cagcacgccc
     8761 cgggccttca ccgccatccc cgcatcgtag ccgtcgcgtt tcttcaagac cccgcccgcg
     8821 cgggagacta ccttcgaaag tatgaacgaa acgtacaagg ccatgaccga gtgcgccgcc
     8881 gaggcggtgc gcgtcgcggg gaaggtgcgc ggagagctgc tcgacggccc gacgacctgc
     8941 gcggagttcg atctgcgggc cctggtgaac cactgggtgc tgtacacctc ctacgggctg
     9001 gagcgccggg cgctgaagca gccgctcccc gaggaactcg tcgcccgcga cttcaccgcc
     9061 gaggacggct gggccgccgc ctacgccgcc cagctcgacc gggccctgca ggcctgggcc
     9121 gaccccgccg cctgggaggg cgagatcccc ctcggcgacg gccgcaccgg cgccgccccc
     9181 cagatcgccg cactgatcgt caaggagatg gccgtgcacg gctgggacgt cgcccgctcc
     9241 atcggcgagg acttcgccat cagcgacgac tccgccgccg tcgtcctgca cgtcgtcgag
     9301 gagaacgccg agctctaccg ccagtaccag ggcttcgccg cccccgtcga agtccccgcc
     9361 tccgcccccc tcttcacccg cgccctggcc ctctccggcc gcgaccccca ccagaccgtc
     9421 tgacccccgg ccccccaccg ggcacctcgg tccccggtcc gccccccatc aggccgcccg
     9481 gtccccggtc cgcccgcatc agaccgttcg gtcccggtcc gctctcatcg gccgttcggt
     9541 cttcgaccgg cacccactgg gccgtctggt cctcggtccg ttctcaccaa accgttcggt
     9601 gctcggtctg atctcacggg gctgttcggt tctcggctcg tccccatcgg gccgtctggt
     9661 cctcggtctg ttctcaccag gccatttggt actcggtccg cccccatcgg gccgttcggt
     9721 cttcgaccga cacccgccgg gccgttcggt cctcggatcg ttttaccggg tggtctggtg
     9781 cttggcctgc tctcaccgga ccgtctgacc ccggcccacc cccatcgggc tgttcgtgct
     9841 cggcctgatc tcacggggct attcggttct cggctcgccc ccatcgggcc gctcggtcct
     9901 cggcctgatc tcatcgggct gttcggtcct ggcctgccgg gccgtttgca tccgggtctg
     9961 tcttcatcag gtcgtctggc cctcggtggg ggtgggaggg tcagcgggct cgggtgatga
    10021 cgaggtcggc gagggcggtg agttcggcga gggggtgggg ggcgggggag acggggtcca
    10081 gggtggcgag ggcctggttg cggagttggg tgaggcggtc gtggctccag gagcggccgc
    10141 cggcggcttc gatgagggcg gcggcctcgg cggggtcgaa gggggcgggg gagcggtaca
    10201 gggcgcgcag ggcgtcggcc tcgggggtgc ccgaggtgag ggcggcgacg acggggaggg
    10261 acttcttgcg gttgagcaga tcggagtaga cgggttttcc cgtctcggcg gggtcgcccc
    10321 agatgccgag caggtcgtcc atgtgctgga aggcgaggcc gaggtgctcg ccgaagagcg
    10381 cgaacgccgc gacctggtcg ggggtgccgc cgcccgcgcc cgcgcccagg gcgcaggcgc
    10441 agcgcatcag ggcgccggtc ttgccgacgg ccatgctgat gcactccgac agcagcacgt
    10501 cgccgcgcgt ctcgaaggac atgtcgaggt tctggccgtg caggaggtcg aggacggcgg
    10561 tggtgagcac ccgggtgggg ccgccggagg ccgccagcgt ctccacggcc agcgtcagca
    10621 gcacgtcccc ggtgaggatc gccgggttgg tgccgaagac ccgccaggcg gccggccggt
    10681 gccgccgggt ctcgtcgccg tccatcacgt cgtcgtgcag cagcgagaag tcgtggatca
    10741 gctccaccgc cacggcggcg ggcaccgcgt cctcggcccg cccgccgacg gcgcgggcag
    10801 ccagcagcgc cagggtgggg cgcagcgcct tgccggagga gccggtgggg ttgccctcgg
    10861 cgtcccacca gcccaggtgg tagccggtga tcagccggac gccgtcgggc agcgagccga
    10921 ccgcctcgcg caacgcgggt tcgaccaggg agcggcccca ttccagtacc tccgcggccg
    10981 gacgggatac ctcgtgcaag gcggtcatga agtcctctct gcgaagagtc gggcggcggc
    11041 catgcccagc ccggtgaggg cgggcaggcc gtgcggggac ggcaggtccc ggacgagctc
    11101 ggcctcgggg tagcgggagg tgtcgcggtg ccagttgagg atcgccacca tccagtcgcg
    11161 gagctcgtcc agataggcgt ccagggctga ccgcgcctcc gccgagaggc cgagccggtc
    11221 gcacaggacg ggcagctcga cggcgatgag gtgctcgaac tggcggcggc gcaggttcat
    11281 cagccgtccg gtgaactcga cggcccgttc cttggagaca cccaggaagt gctccaggat
    11341 caggacgatg ttgtgcagct cgccctcgaa ctcgatctcc ttctggtagg agaacaggtc
    11401 gttgaggaag gtcccgcagt cggctgccgc gttgttgatg gactgtaggg tgcggctggc
    11461 gaagacgtcc tccggtatct gcttttcgta gccgatccgc gacaggaaca tggtcaggtc
    11521 cgagccgaag gtgagcctgc gcatctccac gtagtccacc gggtcgggca gccggtgctg
    11581 cgccgcgccc gcgacctccc aggccatgcc ctcgatcatc accgcgatcg cccggtggaa
    11641 gccctggcgc tggcggtcgg acatggggcc cgcggtgcgc gcccacaggt cggccaggcc
    11701 cgcctcgacc gggttgagcg ggggcggcac cgggccgagg tccaccggca tgaacgccgg
    11761 gagccggcgg gcgaaggccc tggcccccgc cgcgtcccgc gccgcgccgt gcacccgggg
    11821 gaaccagtcg tcgatgtagg tgccccaggt cagccagccc gacgacagca ccagctcgtg
    11881 cgcggtggcg tccgggtcga gcccggccga gcacagcggg aagtcgaagc cgtgcagctg
    11941 ccgctcggtc cacagcgcgc cgggcgtgtc gaagcccatc cggtgggccc aggcgttgtt
    12001 ctcgcggcgc gcgtggtcga ggtgggggct gagccgcagc cggtagggca ggtcgaactc
    12061 cggcagcagg ctcggcccca cccgccggaa cgggacgtgg cggtaggcgc ggaggcggcc
    12121 gaacccgagg ttctgcgggg tgggcaccag cctggccgcg gaggtgccca ggccggaggg
    12181 ggagtaccgc ggcgccccct ggttcatgta ccggctggag cgcatgtgcc attcgtggcc
    12241 gcccgcctgc cagtcctgca gccccttgac ccagcccgcg acggcgagcc gcccctcggg
    12301 cgggacggcg tgctcctcca gcagcaccgg cagctcggtg accgcggtgt ggtcgaactg
    12361 gtagagccgc gagctgagca gctcgttgac gagttcggcc gcggtctggg cgtcgtggcc
    12421 gaagaactcc tggaagacca ggacggcgtt ggacagctcg ccttcgtcct gcacctcgcg
    12481 ctggtaggag aacaggtcgt tgcgcaggtg caccgcgtcg gcgaaggagt cacgcaggac
    12541 gttcaccggc cggctgcgcg cgatgccgtc gggaacctcg cagccggtgg cgtactccac
    12601 caggtccgac gaccagggcg cgccgccgac ccgccgccgc atctcgacgt actcgatggg
    12661 gttggcgatc cgcccggcct cgatgttgac cagctcccac agggactcgt ccagcagggc
    12721 cgcggtgttg gccgcgaacc gctcgcgcca gcgcggcgac atcgccggga cggtgcgcgc
    12781 ccacaggtcc gccaggccgc gttcgaccgg gtgctccggc tcgggcgtcc cggcggccgg
    12841 gtcggcgggc atgaacagcg gcagccggtc caggtaccgc tgggcgcccg ccaggtcgtg
    12901 cgtgcgcttg aacagttcca ggaagtggtc gtcgaagtag aagacccaga cgtaccagtc
    12961 ggtgacggtg tccaggaccg gtccggggga gtccggatgg gtgtaggcgc acagtgtcgc
    13021 gtagtcgtgc gcggcgtact cctcctcggt ccacaccgat ccggggccga ggacgcccat
    13081 ctcgtaggcc cattgcctgg cgtgctccct ggcggactcc acggcggggt tgagccgcgc
    13141 ggggtacggc agatagaact cgggcagctg gaaaggctgc atccggactc ccttctccat
    13201 gagcggcggc tccggctcag aagtggccga tctccacgtt ctccagcacg cccagggcgt
    13261 cgggcaccag caccgcgcac gagtagtagg cgctcaccag gtactggatg acggcctgct
    13321 cggtgatgcc catgaaccgc accgacaggg acggctggta ctcgtcgggg atgccggtct
    13381 ggtgcaggcc gaccacgccc tggtcctcct caccggtccg catcaccagg atcgagctgg
    13441 tctgctggcc ggtgaccggg atcttgttgc aggggaagat cggcacgccg cgccaggcgg
    13501 ggatgtggtg gccgccgacg tccaccggcg tggggtacag gccgcgcttg ttgcactccc
    13561 ggccgaaggc ggcgatcgcc ttggggtggg ccaggaagaa cttcgagccg cgccgccggg
    13621 agagcagctc gtccaggtcg tcgggggtgg gcgggccgct gtgggtctgg atgcgctggc
    13681 ggaggtcggc gttgtgcagc agcccgaact cccggttgtt gatcatctcg tgctcctgcc
    13741 gctcgcgcag ggcctcgatg gtcagccgga gctgctgctc gacctggttc atcggctcgt
    13801 tgaagaggtc ggcgacccgg gtgtgcaccc gcagcacggt ctgggcgacc gacagctcgt
    13861 actcgcgcgg ctcgagctcg tagtcgacga aggtgccggg cagcaccggc tcgcccgcgt
    13921 ggccggcggc gagcgcgatc tccttctcgc cgtggcggtt gtgctcgggc accgggctgg
    13981 ccaggtaggc ggcgacctgc gcctgcagga cgggggagga gccgcggacc tgccggaagt
    14041 cggcgcggct gagggtcagc acggtgcagg aggtctgcgc cttgagggtg tactcccact
    14101 cgtgctcgcc caccagggcg tccgcaccga ggaagtcgcc gtcggcgcac aggcccagcg
    14161 agacctcctc gccgtacttg gagaggccga tcttctggag cttgccgtgg gcgagcagga
    14221 cgacgtactc ggccggggtg ccggcttcgg cgagcacctc gccgggggcc agctcgcgct
    14281 gctcgcagcg gttggccagg gtgcgcagca cctccggatc gtcgaagtcg cgcagcacgg
    14341 gcagttcggc gagctcctcg gggatcacct ggacctgggc gccggtggag aggaactcga
    14401 tgcggccgtc cccgagggtg taggtcaggc gccggttgac ccggtacccg ccgccggaga
    14461 cctggaccca cggcagcatc ttcagcagcc agcgggaggt gatctcctgc atctggggcg
    14521 gggtcttggt ggtggaggcc aggttgcggg ccgccgcggt gccgaggctg agctgctcgg
    14581 cctgcgagga gccgttggcc tgggcgcggt ccgctgtctc ggtcatgcca taccgccttc
    14641 acgtcgggga gcttgcctgc cgaaagttac tgtcagtgac accatgatca caacaagtat
    14701 tttgctgtcc cttgagtaac acccttcaca cgctcaggcc accctcaccg cggccggaag
    14761 atcgcgccgc aggccgcgga caccaccacc gacaccacgg ccgccgccag caccccgccg
    14821 aagacgttcc gctcctcgtg cagcggccgg aaccgccgca cggcgggccg cgcgaccgcc
    14881 tcctgcccgg cgggccgcac cgagcggcgg ggggtcggcg agggccgggc ggacggcggg
    14941 cccgcctccg gcgcggccga ccgcggccgc ggagtcgccc ccgtcgcgga cggcatcgcc
    15001 ggaacggcga cgggcggcac caccgcgggc ggcgcggcca ccggaggccc ggcctcgggg
    15061 ggcacggccg caggaggttc cgccacggga ggcaccggcg ccggaggcgg cgcgggcggc
    15121 gcgggctccg gctgcgccgg ggccggcggt gcgggctcgg gagggaccgg gacgggttcc
    15181 ggcggcacgg gcacgggttc gggttcgggc gccggaggct cgggttcggg aaggaccggg
    15241 acgggttccg gcgccggggg cacgggcgcg ggctcggggg cgggaggcgc cgggggcaaa
    15301 ggcacgggct cgggtgccgg aggctcgggt tcgggcgccg ggggttcggg ttcgggtgcg
    15361 ggaggttcgg gctcgggcgc cggaggctcg ggagcagggg gctccggtgc gggaggttcg
    15421 ggcgcgggag gctcgggcgc aggaggttcg ggcgccgggg gctcgggtgc cggaggcgtc
    15481 gcgcactgcc cggccccgat gacgatggtg acgtccagct ggacgagcac caggtcggcg
    15541 ccgacgcaga tcaccactcc gggctcgggt tcggccgaga cggagggccc cagggccgtc
    15601 agcgcgcaca ggacgccgcc cagcgcggcg aagcgcttga tcatcatggg atctggcgga
    15661 attcccgcca ggcgctctcg aacgccgagg cgtcgacgcc gagcggcccg gtgaaggtgt
    15721 ggttgatggc gaagacgagg tagaccccca ccgccacgct cccggccagc agcaggtagg
    15781 tgaaccgcac cgggccgcgg ggccgggccc cggccagcag cgggaaggcc agcaccagcc
    15841 cggccgtcag gacggtcagc cacaacaccc cgggcggcag gctggcctgg gcgtccacgg
    15901 cccgctgcct gcgggcggcg tagacctgct ccagctgggc ctcgaccgcg gccagcgagt
    15961 ccttctcgtc cttgctgcgc ggctccagca tgccgaggtc ggcgcgcagg gagttcagcc
    16021 gcgcccagcc cgcctcggcg agctcgcccc tggccagcag ccgccactcg cgttcggtga
    16081 cgaagcgggt gtactcccgc agcgcctcgc gggtggccat ggcgctgtcg gcgggcaggt
    16141 cgccggcgtt ccagtaggcc tcggtcagcg cctgcgcctc ggcgtaggtg ttctgccggg
    16201 ccgagtccgc caccgtccac ggcacgatga tcgcgatggc gaacaccagc aggaagagcg
    16261 ccgagaacat ggcgcccgcg tgggaggacg tcggcccgtc gggttcggtg tcgggggagc
    16321 ggtcgggacg ttcggagcgg tcggagcggc gcttggggcg cgagaacatc gggcctccgg
    16381 ggggcggcta cgttatgtag ccaccctaga cctcagtgtc ctgcacgggc gctgaaagta
    16441 accggatcgt ctctctcagg tcaacctgac agggttgaag atgtccgcat aaaccagcag
    16501 cgcgcccatg accagaagga cgaggctcat cgcgtaggtg agcggcagca gcttggccac
    16561 gtccacgtag ccggggtcgg gccggcgcag cagccgcgcg acgccccgct tgacgccctc
    16621 ccacagggcg cccgcgatgt ggccgccgtc cagcggcagc agcgggatga ggttgaacat
    16681 gccgaccgcg aagttgatgg aggccagcag cgccaggaac caggagagct tctcgacccc
    16741 ggggttctcc gaggccagga tctcgccgcc caggcggctg gcgccgacca cgccgatcgg
    16801 cccctcgggg tcgcgctcct cgccgctgaa ggccgcgtgc cagacgccga ccatcttctg
    16861 cggcagctgg acgaacgcct ccagggtgcg ggtggtcatg tcgcccatct gcgtggccac
    16921 gtccgcgggg ccgccctgca cccggtcgat cagcgggctg atccccagga acccgacggt
    16981 gaccaccttg tcggagtcct tcaggtcctg catctggttg gcggtgatct gcaggctgac
    17041 cgggacctcc ttgccgtccc gccgcaccac ggcagggacg gtcctgttcg ccgagtcccg
    17101 gatcaacccc tggagctggg agtagtcctc gatccgctgc ccgccgaagg acacgaaggt
    17161 gtcaccgggc cgcagcccgg ccttggcggc gggggtggag cgcgcggtct cctcgggcgt
    17221 gcactcgcgc gggctgccgt cgggcaggta ggcctgctcg gcggggatga cgcacttgga
    17281 gacgctggag atcgtcgggg tggactgcag ggtgcccagg cccatgatca gcacggcgaa
    17341 gaacaccacg gccagcagca ggttggcggc gggcccggcg aacatgatga ggagcttctg
    17401 ccaccacttc ttgctgtaga agacgcggtc ggcgtcgccc gggccgacct cctccagcgc
    17461 gccctcgcgc gcggagtcga tgagcatctg gaagcggccg gtggaggagg cgcggaccat
    17521 gccctccggg tcgcccttgc ggggcggcag catgccgatc atccggatgt agccgccgag
    17581 cgggatccac ttgatcccgt actcggtctc cccgcgccgc cacgacttca gcgtggggcc
    17641 gaagcccacc atgtactggg gggtgcggac gccgaaccgc ttggcgaacg acaggtgccc
    17701 cagttcgtga aaggcgatcg aggccatcag cagcacgaag aacagcaacg cgccgccgag
    17761 cacgatcagt gtttccatgt gtcaacgacc ccagtccgcc ctccgtggag ggctgtttcc
    17821 gcccgttacc ccgtgccagg gtaagcgatt ccggcgattc cggctcgcct tccccgcccg
    17881 aacgacgggc tctacggtca ttcgccaggg cgtagcctga agcggaattc caagggggga
    17941 gcggcatgga cagtacagac cggtgtgaac cggccggccg cgcctggatc gccgaggcga
    18001 tccgcagggt cgaggccgac aacaaccgga gcgcggacac ccacctccac gtcttccccc
    18061 tgccccccga gtggggcatc gacctctacc tgaaggacga gtcggtgcac cccaccggct
    18121 cgctcaagca ccggctggcc cgctccctgt tcctctatgc gctctccagc ggctggatca
    18181 ccgagggcac cacggtcatc gaggcctcca gcggctcgac cgcggtgagc gaggcctact
    18241 tcgcccggct gctggggctg ccgttcgtcg cggtgatgcc caggagcacc agcccggaga
    18301 agatcgcgct gatcgagttc cagggcggcc gctgccattt cgtcgacgac ccggcgtcga
    18361 tctacgccga ggcggggcgg ctggccgagc gcaccggcgg ccactacctg gaccagttca
    18421 cctacgccga gcgcgccacc gactggcggg ccaacaacaa catcgccgcc tcgatcttcg
    18481 agcagctcgc gctggagccg caccccgagc cggcctggat cgtggtcagc gccggcaccg
    18541 ggggcaccgc ggcgaccatc ggccggtacg tgcgctaccg caggcaccag acgcgcctgg
    18601 cggtcgtgga cccggagggc tcggcgttct acgactcctg ggtgagcggc gacacggcgc
    18661 tgaccgcccc cggctcccgg atcgagggca tcgggcgccc ccgcgtggag ccgtcgttcc
    18721 tgccgtcggt catcgaccgc atgtaccggg tgcccgacgc cgcctcgatc gcctgcatgc
    18781 gctggacgtc ggaggtcacc ggccgcagtg tcggcggctc caccggcacc aacgtctggg
    18841 gcgccctgca ggtcatcggg gagatgcgcg agcgcggcga gcagggcagc gtcgtcaccc
    18901 tgatctgcga cggcggcgag cgctacaccc acacctacct gtccgacgcc tggctcgccg
    18961 ggcagggact ggacctcgcc ccctacttgg cggaactgcg cgccctcctg aacccctgac
    19021 ccccgccaac gcccggcccc ggaacgttca agatccgccc ggggcggctt ggcgccccgc
    19081 cgcccgggta ggagagcggc gtgctggcac tgggtgtggt gctgttcttc ctgctgctca
    19141 tggcgtcgat cgcgctgcac gagctggggc acctgctggt ggccaagcgg ttcggagtgc
    19201 gctgccccca gtacatggtg ggcttcgggc cgacggtcag gtcgtggcgg cgcggggaga
    19261 ccgagtacgg gttcaagtgg gtccccttcg gggggtacgt gcggatgatc ggcatgctgc
    19321 cgccgcgcgc gggggatccc gaggggaggc tgcggcgctc ctcgaccggc cggttcgggc
    19381 agctgatcga ctcggcgcgc aaggagtcgc tggaggaggt cggcccggac gacgccgacc
    19441 gcgtcttcta cgccaagaag tggtggcaga aggcgctgat ctccttcgcc gggccgctga
    19501 tgaacttctt cctggcgttc gtgctgctgg ggatcgccct cgtgggcttc gggatcaagg
    19561 aaccgaccat gggggtcgcg acggtcgcga agtgcgtcgt ccccgccgcc caggccgccc
    19621 gcggatgcgg gccggatgat ccgccgacgc ccgccgcgcg gtccgggctg cggccggggg
    19681 acgagatcgt ctccttcgac ggcgtgccgg tcacccgcta ccggcagttc cagcagttgg
    19741 tgcgcgactc cgccggacgg caggtgcggc tggaggtccg ccgcgacggc cgggaactcg
    19801 tgctcacccc caccctgatc gccaaccggg tcgccgcgct ggacgggcgc tccgggacgg
    19861 tcaccgcggg cttcctcggc atcacgcccg tccaggagta cgtacggcag gacccgctgg
    19921 acgtgctggc gctcatgggg gacatggccg gccgcaccct ggaggcgttt gcggtcctgc
    19981 cgcagaagat ggcaggggtc tgggacgcct ccttccgcgg tgcggagcgc gagtccgaca
    20041 gccccgtggg cgtcgtgggg gcgagccgga tcggcggcga ggtcctggcc gccgacaccc
    20101 gtgccgccga caagatcgtc ctgttcctgc tggtgctcgg ctcgctgaac ttcggcctcg
    20161 ccgccttcaa cctcatcccg ctgctgccgc tggacggcgg caacatcgcg ggctccctgt
    20221 gggagggcct caagcgggcc ttcgcgaggg tggcgggcag gccggcgccc ggcccggtgg
    20281 acgtcgccaa ggcactccct ttgacctacg tggtgggcgc gctgctgctg gccatgggcc
    20341 tgctcatcgc ctacgccgac ctggtcaacc ccatccggct gcgcggctga gaccggatca
    20401 gggctcgaat cccgccagcg cccgcacggt gtcgatggtg tcggcctcct cggcggtctt
    20461 gtcggagcgg tagcgcagca ccctggcgaa ccgcagggcc aggccgcccg ggtagcgggg
    20521 gctgcgctgc agcccgtcga aggcgatctc cacgacctgg accggccgga cggtcaccgt
    20581 ccagccgtcg tcggcggtct tcaggccggt gaaccgctcg gtctgccatg ccagcatgcg
    20641 gtcggtcagg cccttgaacg tcttgccgag catgacgaat ccgccggtgc gcgggtcgcg
    20701 ggcgcccagg tggagattgg acagcgtgcc ccggcggcgt ccgctgcccc gttcgacggc
    20761 caggaccacc aggtcgaggg tgtggcgggg cttcaccttg atccagccgg cgcccctgcg
    20821 gcccgccgtg tagggggtgc ccagcgactt cagcagcacg ccctcgtggc cgcgggcgag
    20881 cgcgccggcg aggaacgcct cggcctccgg cagttcggcg gtgaccgtcc tgggcatgcg
    20941 caggggttcg ggcagcgccc gcacgagcgc ctcgccgcgg acggagcccg gctcgtccag
    21001 gagatccacg ccgtcgaggt gcaggacgtc gaaggcgaac agcgacaggc cgccgatccc
    21061 gccggagcgg gtggccgcgc gggcggaggt gacctggaag gggtggggcc tcccgtcctc
    21121 gcgcaacgcg atcagctcgc cgtccaggat cgccgaccgg aggcccaggg cgcgcaccct
    21181 ttcgacgacc tcggggaccc gggaggtgat ctcctccagg gtgcgggtga agacccggac
    21241 ctgctcgccc tccacgtgca actgggcgcg gatcccgtcc atcttccact cgagggccat
    21301 ctcgcccttg agcgcctcct ccagggaggg cgcggaggag gcgagcatcg gccggacggg
    21361 ccgccccacg cgcagcgtga acgccgagag cgcctccgcc ccgcccgaca gcgcggcgac
    21421 ggcgacggcg gagagcgagc cgcgcagcat gacggcccgc cggacggccg ccgcgggaat
    21481 tccggccgcc ttggcgatcg cctcggtcat gactccttcg agcgcgccct ggcggaggtc
    21541 tccggcgagc agccggacga ggaactcctg ttccggaccg gtcgcctcgg ccagcagggc
    21601 acgcagcagg cgtcgttttc cggccacgga gccggggccg gaggcggcct tgatctcgct
    21661 gaagaccgcg tcgacccggc tgacggacag gcccggcgag ggagaggcgg tcggacggtc
    21721 gccgagggcg gaggggccga tgccgatctg gcgttgcggc agctcaccgg cgaggtagtg
    21781 caccaccagg ggtgcctcct cgggtccggc gtcgcgcagg caggcggcga tgagcgcggt
    21841 cttctcccgg cgcgcggagg tctcggacac ggcccgccag gcggcggcca actcggcgag
    21901 caacatggat ccatcctctc cggaggtaat gacaaagccc ttacgggtcc gtactttcga
    21961 gagcgtgcgc gctgatttcg accgggtcta ttcgcctccc gaaccgcccg agccgagcca
    22021 ctggcggccc cggggctggc aggtggcgtt catctccttc ctcctggcgg cgggaggggt
    22081 gttcttcgcg gtcccgctgc tcctggacga ttccccggaa gacggcgcca tgcccacttt
    22141 gaccgccgag cacgagaacg ccacggagcc acctccggac tccccgccgg aatccgcggc
    22201 tccggagccg gagccgagcc ggccggccga gccttcgccc gccccctccg ccccggcggg
    22261 cgagggcccg ctgacggagt tgccgaagaa ggtctgcgac agcgtctcgg aggccacctt
    22321 cctcaaattg gtgccgaaag gagaaccgga ggaatacggg ggctcccgcg cgggatcatg
    22381 cggatacacc agtgacggcg cggacgattt ccgttatctg cggctggaga cgaggctggc
    22441 ggacgtgacc ggcgacatgg atccgatcac ctcggccaaa tggtcgttcg gtcaggacta
    22501 caagatgcag gaagaagaca agatcaccga cacgctgctt ctggaaaagg tgccgggcct
    22561 cggtgaggag gcctttaggc gggtgtacac cgaggacggt gtggcgaacg tgacgactgc
    22621 tcgcatagcg gtgcgggtgc agaatctgat cgtcaccggg acttacagcc gggccttcga
    22681 aaagaagccg caggaacagc aggacgcgtg tctcgaaggc gctctcgaag tggtgaagga
    22741 agcgctgcgt tcttacacct gacgctcggt tgaccagtgt tacttattgg tagggaagca
    22801 accggcccgg ttggtcggtt ttgcgggtag tatcggacct ccgcccgtcc cgtattgcct
    22861 ggtaatcgcg gtgttatagg tgtcggccac gcaatgcatg ggtttggtta cgcaagatgc
    22921 tggttagtag gtcatgacca gtaagtaaga ggaggcgaag gacatggccg tcaatgaggc
    22981 cggagtgtcc tgggcttagg cgcaggggtc ggaactgaat tcggcggcgg ccggtgagaa
    23041 atcaccggcc gccgccgttt cgtcacccga tgcctcaagc cgggtcgatc cggtggatct
    23101 ggccgttcag gctgagcacg tagagctcgc ccgaggcgtc ctggccgaag gccgagacgt
    23161 tgctgaggtt ctccagggac gt
//
