LOCUS       NZ_JZOJ01000072        20900 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Escherichia coli strain HT2012031
            NODE_213_length_662666_cov_30.682009, whole genome shotgun sequence.
ACCESSION   NZ_JZOJ01000072
VERSION     NZ_JZOJ01000072.1
KEYWORDS    WGS; RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 662740)
  AUTHORS   Lu,S., Jin,D., Wu,S., Yang,J., Lan,R., Bai,X., Liu,S., Meng,Q.,
            Yuan,X., Zhou,J., Pu,J., Chen,Q., Dai,H., Hu,Y., Xiong,Y., Ye,C. and
            Xu,J.
  TITLE     Insights into the evolution of pathogenicity of Escherichia coli
            from genomic analysis of intestinal E. coli of Marmota himalayana in
            Qinghai-Tibet plateau of China
  JOURNAL   Emerg Microbes Infect 5 (12), e122 (2016)
   PUBMED   27924811
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662740)
  AUTHORS   Xu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAR-2015) New pathogen brach, National institute for
            communicable disease control and prevention, P.O. Box 5 Changping,
            Beijing, Beijing 102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. April 2014
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 40.0x
            Sequencing Technology             :: Illumina GAIIx
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002972405.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 01:49:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,368
            CDSs (total)                      :: 5,292
            Genes (coding)                    :: 4,983
            CDSs (with protein)               :: 4,983
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 309
            CDSs (without protein)            :: 309
            Pseudo Genes (ambiguous residues) :: 0 of 309
            Pseudo Genes (frameshifted)       :: 78 of 309
            Pseudo Genes (incomplete)         :: 257 of 309
            Pseudo Genes (internal stop)      :: 43 of 309
            Pseudo Genes (multiple problems)  :: 62 of 309
            Pseudo Genes (short protein)      :: 2 of 309
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:14:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 596429
            Orig. end                         :: 617329
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JZOJ01000072.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20900
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20900
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20900
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10900](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10900
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(383..397)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.75"
                     /tool="antismash"
     gene            384..2375
                     /gene="cyoB"
                     /locus_tag="VE62_RS16005"
     CDS             384..2375
                     /EC_number="7.1.1.-"
                     /GO_function="GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyoB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444673.1"
                     /locus_tag="VE62_RS16005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="WP_021520563.1"
                     /transl_table=11
                     /translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWAYLW
                     KEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFT
                     AHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVG
                     EFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTM
                     FKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWA
                     WGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGA
                     GANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGV
                     LLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFW
                     FWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMY
                     VSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWEMKEKGEAYKK
                     PDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVD
                     YYVPVAEIEKLENQHFDEITKAGLKNGN"
     gene            2365..2979
                     /gene="cyoC"
                     /locus_tag="VE62_RS16010"
     CDS             2365..2979
                     /EC_number="7.1.1.-"
                     /GO_function="GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0022904 - respiratory electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /gene="cyoC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414964.1"
                     /locus_tag="VE62_RS16010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="WP_000179819.1"
                     /transl_table=11
                     /translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILFA
                     TYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVISWLAL
                     TWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVLMVQ
                     IARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     gene            2979..3308
                     /gene="cyoD"
                     /locus_tag="VE62_RS16015"
     CDS             2979..3308
                     /EC_number="7.1.1.-"
                     /codon_start=1
                     /gene="cyoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308510.1"
                     /locus_tag="VE62_RS16015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="WP_000019796.1"
                     /transl_table=11
                     /translation="MSHSNASSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPAV
                     ILGTILAMAVVQILVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNLNY
                     NMMMH"
     gene            3320..4210
                     /gene="cyoE"
                     /locus_tag="VE62_RS16020"
     CDS             3320..4210
                     /EC_number="2.5.1.141"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008495 - protoheme IX farnesyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0048034 - heme O biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyoE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308509.1"
                     /locus_tag="VE62_RS16020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="heme o synthase"
                     /protein_id="WP_001682647.1"
                     /transl_table=11
                     /translation="MIFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLVG
                     VSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPVVSLVYATLLGIAGFMLLWFG
                     ANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDSGAA
                     ILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAVATLM
                     LSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALSVMMSV
                     DFMVPDSHTLLAAVW"
     misc_feature    complement(4281..4295)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.79"
                     /tool="antismash"
     misc_feature    complement(4282..4295)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            4359..>5428
                     /locus_tag="VE62_RS16025"
     CDS             4359..>5428
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414961.4"
                     /locus_tag="VE62_RS16025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_249922394.1"
                     /transl_table=11
                     /translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQGA
                     SEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIWGI
                     ILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITHKLG
                     LHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLNFGIM
                     CLHILLMSTFVALPGQMADAGLPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRKMKQVF
                     VFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAGYKGTAM
                     GVYSTSQFLGVAIGGSL"
     assembly_gap    5429..5507
                     /estimated_length=79
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <5508..5800
                     /locus_tag="VE62_RS29260"
                     /pseudo=""
     CDS             <5512..5800
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308508.2"
                     /locus_tag="VE62_RS29260"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="GWIDGMFDGQGVFLAGAMLAAVWLAVASTMKEPPYVSSLRIEIPA
                     NIAANEALKVRLLETEGIKEVLIAEEEHSAYVKIDSKVTNRFEVEQAIRQA"
     gene            complement(5928..6419)
                     /gene="yajQ"
                     /locus_tag="VE62_RS16030"
     CDS             complement(5928..6419)
                     /codon_start=1
                     /gene="yajQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414960.2"
                     /locus_tag="VE62_RS16030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotide binding protein YajQ"
                     /protein_id="WP_001138904.1"
                     /transl_table=11
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDAS
                     KTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGIES
                     ATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKNFRD
                     "
     gene            6587..7498
                     /gene="panE"
                     /locus_tag="VE62_RS16035"
     CDS             6587..7498
                     /EC_number="1.1.1.169"
                     /GO_function="GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414959.1"
                     /locus_tag="VE62_RS16035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="WP_021540802.1"
                     /transl_table=11
                     /translation="MKITVLGCGALGQLWLTALCKQGHDVQGWLRVPQPYCSVNLVETD
                     GSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGTIE
                     ELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVLPDV
                     AWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIEREGHHT
                     SAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVPENTRL
                     FETVKRKESEYERIGTGLPRPW"
     gene            7461..8051
                     /gene="yajL"
                     /locus_tag="VE62_RS16040"
     CDS             7461..8051
                     /EC_number="3.5.1.124"
                     /codon_start=1
                     /gene="yajL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308505.2"
                     /locus_tag="VE62_RS16040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="protein deglycase YajL"
                     /protein_id="WP_001276309.1"
                     /transl_table=11
                     /translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLAI
                     TCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIVAA
                     ICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWQDKRVVWDARVKLLTSQGPGTAID
                     FGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(8105..9553)
                     /gene="thiI"
                     /locus_tag="VE62_RS16045"
     CDS             complement(8105..9553)
                     /EC_number="2.8.1.4"
                     /GO_function="GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /locus_tag="VE62_RS16045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="WP_105484859.1"
                     /transl_table=11
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVR
                     HWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQLEG
                     KTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDDRLLLIK
                     GRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEISVRQ
                     VAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVAERYGV
                     QALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTM
                     PEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTEQEVVEVE
                     TVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQSKTWLLWCER
                     GVMSRLQALYLREQGFNNVKVYRP"
     misc_feature    complement(9684..9700)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.88"
                     /tool="antismash"
     gene            9759..10001
                     /gene="xseB"
                     /locus_tag="VE62_RS16050"
     CDS             9759..10001
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308503.1"
                     /locus_tag="VE62_RS16050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_001124935.1"
                     /transl_table=11
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQL
                     ARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     gene            10001..10900
                     /gene="ispA"
                     /locus_tag="VE62_RS16055"
     CDS             10001..10900
                     /EC_number="2.5.1.10"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414955.1"
                     /locus_tag="VE62_RS16055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="WP_000347220.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-67, bitscore:
                     222.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGGK
                     RLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCHVK
                     FGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQALDLD
                     AEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLAFQVQ
                     DDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQLTEQS
                     LDTSALEALADYIIQRNK"
     gene            10925..12787
                     /gene="dxs"
                     /locus_tag="VE62_RS16060"
     CDS             10925..12787
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308501.1"
                     /locus_tag="VE62_RS16060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_000006816.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 5.2e-119,
                     bitscore: 391.7, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.4e-06, bitscore:
                     22.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSR
                     SSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGL
                     HPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEA
                     MNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPI
                     KELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIM
                     TKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLM
                     AITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRA
                     YDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECR
                     QMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPE
                     AAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAH
                     RKPVPVLNIGLPDFFIPQGTQEEMRAELGLDATGMEAKIKAWLA"
     gene            12842..13816
                     /gene="yajO"
                     /locus_tag="VE62_RS16065"
     CDS             12842..13816
                     /EC_number="1.17.1.-"
                     /codon_start=1
                     /gene="yajO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414953.2"
                     /locus_tag="VE62_RS16065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-deoxyxylulose-5-phosphate synthase YajO"
                     /protein_id="WP_001199806.1"
                     /transl_table=11
                     /translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIK
                     RALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSRAQ
                     ILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQ
                     FAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRP
                     WGETTARLVSDEVGKNLYQESNENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAA
                     PIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPVTGFK"
     gene            complement(13870..14388)
                     /gene="pgpA"
                     /locus_tag="VE62_RS16070"
     CDS             complement(13870..14388)
                     /GO_function="GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414952.1"
                     /locus_tag="VE62_RS16070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="WP_000154049.1"
                     /transl_table=11
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLAA
                     IPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITLMA
                     LPTNDWQWVTAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILYFIG
                     HHWPLGILS"
     gene            complement(14366..15343)
                     /gene="thiL"
                     /locus_tag="VE62_RS16075"
     CDS             complement(14366..15343)
                     /EC_number="2.7.4.16"
                     /GO_function="GO:0009030 - thiamine-phosphate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414951.1"
                     /locus_tag="VE62_RS16075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiamine-phosphate kinase"
                     /protein_id="WP_000742109.1"
                     /transl_table=11
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAIS
                     TDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLESFS
                     DSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGTPGD
                     SAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLISDLG
                     HIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNRGALDV
                     ALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYDHFATP"
     gene            complement(15421..15840)
                     /gene="nusB"
                     /locus_tag="VE62_RS16080"
     CDS             complement(15421..15840)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308496.1"
                     /locus_tag="VE62_RS16080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_000801125.1"
                     /transl_table=11
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDV
                     LYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKVAI
                     NEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            complement(15860..16330)
                     /gene="ribE"
                     /locus_tag="VE62_RS16085"
     CDS             complement(15860..16330)
                     /EC_number="2.5.1.78"
                     /GO_component="GO:0009349 - riboflavin synthase complex
                     [Evidence IEA]"
                     /GO_function="GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="ribE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /locus_tag="VE62_RS16085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="WP_001021161.1"
                     /transl_table=11
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVK
                     DENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHV
                     AQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            complement(16419..17522)
                     /gene="ribD"
                     /locus_tag="VE62_RS16090"
     CDS             complement(16419..17522)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="ribD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706302.1"
                     /locus_tag="VE62_RS16090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
                     RibD"
                     /protein_id="WP_001150440.1"
                     /transl_table=11
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQR
                     AGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVAAMQDPN
                     PQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGRTAM
                     ASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWSELDEQTQGLYPQQ
                     NLRQPVRIVIDSQNRVTPEHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHKGHLDL
                     VVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGNDARGLCTLPGLE
                     KLADAPQFKFKEIRHVGPDVCLHLVGA"
     gene            complement(17526..17975)
                     /gene="nrdR"
                     /locus_tag="VE62_RS16095"
     CDS             complement(17526..17975)
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /locus_tag="VE62_RS16095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_000543535.1"
                     /transl_table=11
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAE
                     LVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVP
                     SKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
     misc_feature    complement(17984..17999)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.49"
                     /tool="antismash"
     gene            18126..18665
                     /gene="yajI"
                     /locus_tag="VE62_RS16100"
     CDS             18126..18665
                     /codon_start=1
                     /gene="yajI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414946.4"
                     /locus_tag="VE62_RS16100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3251 domain-containing protein"
                     /protein_id="WP_001298536.1"
                     /transl_table=11
                     /translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLNK
                     ETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDTDGTTLTLRIQ
                     GESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKGMSV
                     DQLGFVRIHDIQPVMQ"
     misc_feature    complement(18674..18690)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.74"
                     /tool="antismash"
     misc_feature    18915..18930
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            18964..19848
                     /gene="tsx"
                     /locus_tag="VE62_RS16105"
     CDS             18964..19848
                     /codon_start=1
                     /gene="tsx"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308491.1"
                     /locus_tag="VE62_RS16105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="WP_001295827.1"
                     /transl_table=11
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGSY
                     HTRFGPQLRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEIEP
                     RFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMSLSM
                     NVYAKYQWQNYGAANENEWDGYRFKVKYFVPITDLWGGQLSYIGFTNFDWGSDLGDDSG
                     YANNGIKTRTNNSIASSHILALNYDHWHYSVVARYWHNGGQWNDDAELNFGNGNFNVRS
                     TGWGGYLVVGYNF"
     gene            complement(19886..20233)
                     /gene="yajD"
                     /locus_tag="VE62_RS16110"
     CDS             complement(19886..20233)
                     /codon_start=1
                     /gene="yajD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308490.1"
                     /locus_tag="VE62_RS16110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HNH nuclease YajD"
                     /protein_id="WP_000974813.1"
                     /transl_table=11
                     /translation="MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTVH
                     HIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYNPF
                     ADLKAMMNKKK"
ORIGIN
        1 tcgccaacga acccggtact tatgacggta tctccgccag ctacagcggc ccgggcttct
       61 caggcatgaa gttcaaagct attgcaacac cggatcgcgc cgcattcgac caatgggtcg
      121 caaaagcgaa acagtcgccg aacagcatgt ctgacatggc agcgttcgaa aaactggccg
      181 cgcctagcga atacaaccag gtggaatatt tctccaacgt gaaaccagac ttgtttgccg
      241 atgtgattaa caagtttatg gctcacggta agagcatgga catgacccag ccagaaggtg
      301 agcacagcgc acatgaaggt atggaaggca tggacatgag ccacgcggaa tccgcccatt
      361 aaaggggttg aggaagaata aagatgttcg gaaaattatc acttgatgca gtcccgttcc
      421 atgaacctat cgtcatggtt acgatcgctg gcattatttt gggaggtctg gcgctcgttg
      481 gcctgatcac ttacttcggt aagtgggcct acctgtggaa agagtggctg acctccgtcg
      541 accataaacg cctcggtatc atgtatatca tcgtggcgat tgtgatgttg ctgcgtggtt
      601 ttgctgacgc cattatgatg cgtagccagc aggcccttgc ctcggcgggc gaagcgggct
      661 tcctgccacc tcaccactac gatcagatct tcaccgcgca cggcgtgatt atgatcttct
      721 tcgtggcgat gcctttcgtt atcggtctga tgaacctggt ggttccgctg cagatcggcg
      781 cgcgtgacgt tgcgttcccg ttcctcaaca acttaagctt ctggtttacc gttgttggtg
      841 tgattctggt taacgtttct ctcggcgtgg gcgaatttgc gcagaccggc tggctggcct
      901 atccaccgct atcgggaata gagtacagtc cgggagtcgg tgtcgattac tggatatgga
      961 gtctccagct atccggtata ggtacgacgc ttaccggtat caacttcttc gttaccattc
     1021 tgaagatgcg cgcaccgggc atgaccatgt tcaagatgcc agtatttacc tgggcatcac
     1081 tgtgcgcgaa cgtactgatt attgcttcct tcccaattct gacggttacc gtcgcgttgt
     1141 tgaccctgga tcgctatctg ggcacccatt tctttaccaa cgatatgggt ggcaacatga
     1201 tgatgtatat caacctgatt tgggcctggg gccacccgga agtttacatc ttgatcctgc
     1261 ctgtattcgg tgtgttctcc gaaattgcgg caaccttctc gcgtaaacgt ctgtttggtt
     1321 atacctcgct ggtatgggca accgtctgta tcaccgtgct gtcgttcatc gtctggctgc
     1381 accacttctt tacgatgggt gcgggcgcga acgtaaacgc cttctttggt atcaccacga
     1441 tgattatcgc catcccgacc ggggtgaaga tcttcaactg gctgttcacc atgtatcagg
     1501 gccgcatcgt gttccattct gcgatgctgt ggaccatcgg ttttatcgtc accttctcgg
     1561 tgggcgggat gactggcgtg ctgctggcag taccgggcgc ggacttcgtt ctgcataaca
     1621 gcctgttcct gattgcgcac ttccataacg tgatcatcgg cggcgtggtc ttcggctgct
     1681 tcgcagggat gacctactgg tggcctaaag cgttcggttt caaactgaac gaaacctggg
     1741 gtaaacgtgc gttctggttc tggatcatcg gcttcttcgt tgcctttatg ccactgtatg
     1801 cgctgggctt catgggcatg acccgtcgtt tgagccagca gattgacccg cagttccaca
     1861 ccatgctgat gattgcagcc agcggtgcgg tactgattgc gctgggtatt ctctgcctcg
     1921 ttattcagat gtacgtttct attcgtgacc gcgaccagaa ccgtgacctg actggcgacc
     1981 cgtggggtgg ccgtacgctg gagtgggcaa cctcttcccc gcctccgttc tataactttg
     2041 ccgttgtgcc gcacgttcac gaacgtgatg cattctggga aatgaaagag aaaggcgaag
     2101 cgtacaaaaa gcctgaccac tatgaagaaa ttcatatgcc gaaaaacagc ggtgccggta
     2161 tcgtcattgc ggctttctcc accatcttcg gtttcgccat gatctggcat atctggtggc
     2221 tggcgattgt tggcttcgca ggcatgatca tcacctggat cgtgaaaagc ttcgacgagg
     2281 acgtggatta ctacgtgccg gtggcagaaa tcgaaaaact ggaaaaccag catttcgatg
     2341 agattactaa ggcagggctg aaaaatggca actgatactt tgacgcacgc gactgcccac
     2401 gcgcacgaac acgggcacca cgatgcaggc ggaaccaaaa tcttcggatt ttggatctac
     2461 ctgatgagcg actgcattct gttctctatc ttgtttgcta cctatgccgt tctggtgaac
     2521 ggcaccgcag gtgggccgac aggtaaggac attttcgaac tgccgttcgt tctggttgaa
     2581 actttcttgc tgttgttcag ctccatcacc tacggcatgg cggctatcgc catgtacaaa
     2641 aacaacaaaa gccaggtgat ctcctggctg gcgttgacat ggttgtttgg tgccggattt
     2701 atcgggatgg aaatctatga attccatcac ctgattgtta acggcatggg tccggatcgc
     2761 agcggcttcc tgtcagcatt ctttgcgctg gtcggcacgc acggtctgca cgtcacttcc
     2821 ggtcttatct ggatggcggt gctgatggtg caaatcgccc gtcgcggcct gaccagcact
     2881 aaccgtaccc gcatcatgtg cctgagcctg ttctggcact tcctggatgt ggtttggatc
     2941 tgtgtgttca ctgttgttta tctgatgggg gcgatgtaat gagtcattct aacgcaagca
     3001 gcggcgcatc ccatggcagc gtaaagacct acatgacagg ctttatcctg tcgataatcc
     3061 tgacggtaat tccgttctgg atggtgatga caggggctgc ctctccggcc gtaattctgg
     3121 gaacaatcct ggcaatggca gtggtacaga ttctggtgca tctggtgtgc ttcctgcaca
     3181 tgaataccaa atcagatgaa ggctggaata tgacggcatt tgtcttcacc gtgctaatca
     3241 tcgccatcct ggttgtgggc tccatttgga ttatgtggaa cctcaactac aacatgatga
     3301 tgcactaaga gcggcggtta tgatatttaa gcaatacctg caagtaacga aaccaggcat
     3361 catctttggc aacctgatct cggtgattgg gggattcctg ttggcctcaa agggcagcat
     3421 tgattatccc ctgtttatct acacgctggt tggggtgtca ctggttgtgg cgtcgggttg
     3481 tgtgtttaac aactacatcg acagggatat cgaccgaaag atggaaagga cgaagaatcg
     3541 ggtgctggtg aaaggcctga tctctcctgt tgtctcgctg gtgtacgcca ccttgctggg
     3601 tattgctggc tttatgctgc tgtggtttgg cgcgaatccg ctggcctgct ggctgggggt
     3661 gatgggcttt gtggtttatg tcggcgttta tagcctgtac atgaaacgtc attctgtcta
     3721 cggcacattg attggttcgc tctccggcgc tgcgcctccg gtgatcggtt actgtgcggt
     3781 aaccggcgag ttcgatagcg gcgcagcgat cctgctggct atcttcagcc tgtggcagat
     3841 gcctcactct tatgccatag ccattttccg ctttaaggat tatcaggcgg caaacattcc
     3901 ggtactgccg gtggtgaaag gcatttcggt ggcgaagaat cacatcacgc tgtatatcat
     3961 cgcctttgcc gttgccacgc tgatgctctc tcttggcggc tacgctgggt ataaatatct
     4021 ggtggtcgcc gctgcggtga gcgtctggtg gttaggcatg gctctgcgcg gctataaagt
     4081 tgctgatgac agaatctggg cgcgcaagct gttcggtttc tctatcatcg ccatcactgc
     4141 cctctcggtg atgatgtccg ttgattttat ggtgccggac tcgcatacgc tgctggctgc
     4201 tgtgtggtaa cacaacctct cagttaaaaa ggtgctacgg cacctttttt cttagcatta
     4261 gaatcatatc cctctcgaaa tatttactaa aaaatccgca tgtttacccc attcgtttgc
     4321 cgctttacac tagtcgcgaa tttaaaacag aggtggtaat gaacgattat aaaatgacgc
     4381 caggtgagcg gcgcgcgacc tggggtttag ggaccgtatt ttcattacgc atgctgggca
     4441 tgttcatggt tctgccggtt ctgaccacgt acggcatggc tctgcaaggt gccagcgaag
     4501 cattaatcgg tattgccatt ggtatttatg gtctgactca ggccgttttt cagattccgt
     4561 ttggcctgct ttcagaccgc attggtcgca aaccattaat tgtcggtggg ctggcggtgt
     4621 ttgccgccgg tagcgttatc gctgcgctct ctgactccat ctggggaatt attctgggcc
     4681 gggcgctaca aggctccggt gcgattgccg ctgccgttat ggcgctgctt tccgatctca
     4741 cgcgcgaaca aaaccgcacc aaagcgatgg cgtttatcgg cgtgagcttt ggcattacct
     4801 ttgccattgc gatggtgctt ggcccgatca tcactcacaa acttgggctg cacgcgctgt
     4861 tctggatgat cgctattctg gcaacaaccg gcattgcgtt gaccatttgg gttgtgccca
     4921 acagtagcac tcacgtactt aatcgtgagt ccggaatggt gaaaggcagt ttcagtaaag
     4981 tgctggcgga accgcggctg ctgaaactca actttggcat tatgtgtctg catattttgc
     5041 tgatgtcgac ctttgttgcc ctgcccggac agatggctga tgcggggtta ccggcggctg
     5101 aacactggaa ggtctacctg gcaacgatgt taatcgcctt tggctcggtc gtgcctttca
     5161 ttatctacgc tgaagttaag cgcaaaatga agcaagtctt tgtcttctgc gtcgggttga
     5221 tcgtggtcgc ggaaattgtg ttgtggaacg cacaaacgca gttctggcaa ctggtggtcg
     5281 gcgtgcagct tttctttgtg gcgtttaatt tgatggaagc ccttctgcct tcacttatca
     5341 gtaaagaatc gccagcaggt tacaaaggta cggcgatggg tgtttactcc accagccagt
     5401 ttcttggcgt ggcgattggc ggttcactnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnngcg gctggattga
     5521 cggcatgttt gacggtcagg gcgtatttct cgctggcgca atgctggccg cagtgtggct
     5581 ggcagtcgcc agtaccatga aagaaccgcc gtatgtcagc agcttgcgca ttgaaatccc
     5641 ggcgaacatt gccgcaaacg aggcgttaaa agtgcgtttg ctggaaactg aaggcatcaa
     5701 agaagtgttg attgcagaag aagaacattc agcttatgtg aaaatcgaca gcaaagtgac
     5761 gaatcgcttt gaggttgaac aggcaattcg ccaggcataa aagcgaggcg aaattgcctg
     5821 ctgcgctacg cttatcaggc ctactaagtt cctgagttac aaacctttgt aggccgaatc
     5881 aggcgttcat gccgcatctg acatgaacaa agcgcaggtt gtcgcgatta atcgcggaag
     5941 tttttgaact ggaacggctg accgagatcg ccaccacgta ccatcgccat gacagcctgt
     6001 aaatcatcac gagatttacc cgttacgcgg atctcatcgc cctgaatttg cgcctgcact
     6061 ttcagtttgc tgtctttgat cattttgacg attttcttct gagtcgcgct ctcaatgccc
     6121 tgtttcagtt tcgcttccac aaaccaggtt ttaccgctat gaacgatatt ttccggtaca
     6181 tccagtgaac tgccttcaat gccgcgcttc agcaacttgg cacgcagaat atccagcaac
     6241 tgattgacct ggaagtcgga ctcgctcaac actttgatgg ttttgctggc gtcattcagc
     6301 tcaaatgagg cttcaacgtt acggaagtca aaacgggact ccacttcgcg gctcgcgtta
     6361 tcgaccgcgt tacgtgcttc ctgaagatca acttcagaga caatatcgaa agatggcatc
     6421 ttttcctctc ccttcatttt tgatgcgaag cataatacct gcaaagttaa ataaccaaca
     6481 gtcctgcacc aggacgtatc ccttaattgt gcatagtcgc aacagcatgc acaattaagg
     6541 gatagcctta ttgaacaccc ggagtggttg cgggtgagga ggaacaatga aaattaccgt
     6601 attgggatgc ggtgccttag ggcaattatg gcttacagca ctttgtaaac agggtcacga
     6661 cgttcagggc tggctgcgcg taccgcaacc ttattgtagt gtgaatctgg ttgagacaga
     6721 tggttcgata tttaacgaat cgctgaccgc caacgatccc gattttctcg ccaccagcga
     6781 tctgctcctg gtgacgctga aagcatggca ggtttccgat gccgtcaaaa gcctcgcgtc
     6841 cacactgcct gtaaccacgc caatactgtt aattcacaac ggcatgggca ccatcgaaga
     6901 gttgcaaaac attcagcagc cattactgat gggcaccacc acccatgcag ctcgccgcga
     6961 cggcaatgtc attattcatg tggcaaacgg tatcacgcat attggtccgg cacggcaaca
     7021 ggacggcgat tacagttatc tggcggatat tttgcaaacc gtgttacctg acgtcgcgtg
     7081 gcataacaat attcgcgctg agttgtggcg caagctggca gtcaactgtg tgattaatcc
     7141 actgaccgcc atctggaatt gcccgaatgg tgaattacgt catcatccgc aagaaattat
     7201 gcagatatgc gaagaagtcg cggcagtgat cgaacgcgaa gggcatcata cttcagcaga
     7261 agatttgcgt gattacgtga tgcaggtgat tgatgcaaca gcggaaaata tctcgtcgat
     7321 gttgcaggat atccgcgcgc tgcgccacac cgaaatcgac tatatcaatg gttttctctt
     7381 acgccgcgcc cgcgcgcatg ggattgccgt accggaaaac acccgcctgt ttgaaacggt
     7441 aaaaagaaag gagagtgaat atgagcgcat cggcactggt ttgcctcgcc cctggtagtg
     7501 aagagactga agccgtcacc actatcgacc tcttggttcg cggcggtatc aaagtcacca
     7561 ctgccagcgt cgccagcgat ggtaacctgg cgattacctg ctcgcgcggc gtgaagctgc
     7621 tggcggatgc gccgctggtt gaagtggctg atggcgaata tgacgtgatt gtgctgcctg
     7681 gtggcatcaa aggcgcagag tgttttcgcg atagcaccct gctggttgaa accgttaaac
     7741 agttccaccg ttccgggcgt atcgtcgcgg ctatttgcgc cgcgccagcc accgtgctgg
     7801 tcccgcacga tatcttcccg attggcaata tgaccggctt cccgacgctg aaagacaaaa
     7861 tacccgccga acaatggcag gacaagcgcg tcgtctggga tgcacgggta aaattgctga
     7921 ccagccaggg gccaggtaca gctatcgact ttggtctgaa aattatcgac ctgctggttg
     7981 ggcgcgagaa agcccatgaa gtggcatcac aactggtgat ggcggcaggg atttataatt
     8041 attacgagta gtgtcggatg cggtaaacgt cgcatctgac cagatgcgac gttacaacca
     8101 catattacgg gcgatacacc ttcacattgt taaagccctg ctcgcgcaga tagagcgcct
     8161 gcaggcggct catcaccccg cgctcacacc acaacagcca ggttttgctc tggtcgagat
     8221 cgccaaattt ggtgctcagt ttatagaacg gcagagaaac cacatcaatc ccttcgactt
     8281 tcagtggctt atcttcctgt tcatcgatag aacggatatc gaggatcacg tcgttcgggc
     8341 cgaagccatt gacggtttcc acttccacca cttcctgctc ggtctgctgg gcgatttcgc
     8401 ggatatcaac gttattcgct tcctccacca ctttatcgag aatgctgaag tcgaacttct
     8461 cttcttccgc ttcaatcttc gatttaaccg ctttcaccgt cgggcttttg gaaatcacgc
     8521 cgcaatattc cggcatcgtg cgggcaaagt cttcggtgcc aatctggcga gccaggttga
     8581 tgatgtgctc tttgtcgtaa gagatcagcg gacgcaggat cagcgtgtcg gagacgttat
     8641 caatcaggcg taggttggtc agcgtctggc tggacacctg gccgagcgct tcaccggtaa
     8701 ccagcgcctg tacgccgtaa cgttctgcca ctttggacgc ggcacgcacc atcatacgtt
     8761 tgaggataac gcccatctga ccgtcgtcga ttttctcgag aatttccccg acgaccggtt
     8821 cgaaattaat agcgacaaaa cgcacgcggt gggagctgcc aaagcggttc cacagataat
     8881 gcgccacctg acgtacgcta atttcatgcg ccgcgccgcc gaggttaaag aagcagtaat
     8941 gcacgcggca gccgcgacgc atcaacatat aactggaaac accggagtcg aaaccaccgg
     9001 aaatgagcga caacacatct tcctgggtgc cgatcgggaa accgccaata ccttcgtagc
     9061 ggcctttaat cagcagcaga cgatcgtctt ccacttccag atggacagtc acttccggat
     9121 tggtcagctt cacgcgcgcg gattcaatat gctgatttaa accgccgccg acgtaacgtt
     9181 ccacatcaat cgagctaaaa tcatgtttgc cgcggcgctt cacgcgtacg caaaaggttt
     9241 tgccttccag ctgatcgcga tattgaacca acgctttctc gaaaatatcg tgcatgtcgg
     9301 taaacggcac gtcttcgact tcgagaatat ggtggatacc cggaatacgg gtcagggcgt
     9361 cgcgaatagc cagacgctgg ttttcatctt ttgcgcgaac ttcgatgtta tcccagtggc
     9421 ggacgacagc gagcgtctca tcatagtgct ttaaaacgtt acgaatgttc ccggtaagga
     9481 tttttataaa gcgcaagcgc acagattggc ttttgatggt gatttccggg aacaatttaa
     9541 tgataaactt catggcggca atggttcgtt ggcaagcctt aagcgacttg tatagggaaa
     9601 aatacagcag cccacacctg cggctgcatc caggcgcgga agtataccac taacatcgct
     9661 ttgctgcgca catcacctta ccattgcgcg ttatttgcta tttgccctga gtccgttacc
     9721 atgacggggc gaaaaatatt gagagtcaga cattcattat gccgaagaaa aatgaggctc
     9781 ccgccagctt tgaaaaggcg ctgagcgagc tggaacagat tgtaacccgt ctggaaagtg
     9841 gcgacctgcc gctggaagag gcgctgaacg aattcgaacg cggcgtgcag ctggcacgtc
     9901 aggggcaggc caaattacaa caagccgaac agcgcgtaca aattctgctg tctgacaatg
     9961 aagacgcctc tctaacccct tttacaccgg acaatgagta atggactttc cgcagcaact
    10021 cgaagcctgc gttaagcagg ccaaccaggc gctgagccgt tttatcgccc cactgccctt
    10081 tcagaacact cccgtggtcg aaaccatgca gtatggcgca ttattaggtg gtaagcgcct
    10141 gcgacctttc ctggtttatg ccactggtca tatgttcggc gttagcacaa acacactgga
    10201 cgcacccgct gccgccgtag agtgtatcca cgcttactca ttaattcatg atgatttacc
    10261 ggcgatggat gatgacgatc tgcgtcgcgg tttgccgacc tgccatgtga agtttggcga
    10321 agcaaacgcg attctcgctg gtgacgcttt acaaacgctg gcgttctcga ttctaagcga
    10381 tgccgatatg ccggaagtgt cagatcgcga cagaatttcg atgatttctg agctggcgag
    10441 cgccagcggt attgccggaa tgtgcggtgg tcaggcatta gatttagacg ctgaaggcaa
    10501 acacgtacct ctggacgcgc ttgagcgtat tcatcgtcat aaaaccggcg cattgattcg
    10561 cgccgccgtt cgccttggtg cattaagcgc cggagataaa ggacgtcgtg ctctgccagt
    10621 actcgacaag tacgcagaga gcatcggcct tgccttccag gttcaggatg acatcctgga
    10681 tgtggtggga gatactgcaa cgttgggaaa acgccagggt gccgaccagc aacttggtaa
    10741 aagtacctac cctgcacttc tgggtcttga gcaagcccgg aagaaagccc gggatctgat
    10801 cgacgatgcc cgtcagtcgc tgaaacaact gactgaacag tcactcgata cctcggcact
    10861 ggaagcgcta gcggactaca tcatccagcg taataaataa acaataagta ttaataggcc
    10921 cctgatgagt tttgatattg ccaaataccc gaccctggca ctggtcgact ccacccagga
    10981 gttacgactg ttgccgaaag agagtttacc gaaactctgc gacgaactgc gccgctattt
    11041 actcgacagc gtgagccgtt ccagcgggca cttcgcctcc gggctgggca cggtcgaact
    11101 gaccgtggcg ctgcactatg tctacaatac cccgtttgac cagttaatct gggatgtggg
    11161 gcatcaggct tatccgcata aaattttgac cgggcgccgc gacaaaatcg gcaccatccg
    11221 tcagaaaggt ggcctgcacc cgttcccgtg gcgcggcgaa agcgaatatg acgtattaag
    11281 cgtcgggcat tcatcaacct ccatcagtgc cggaattggg atcgcagttg ctgccgagaa
    11341 agaaggcaaa aatcgccgca ccgtctgtgt cattggcgat ggcgcgatta ctgctggcat
    11401 ggcgtttgaa gcgatgaatc acgcgggcga tatccgtcct gatatgctgg tggttctcaa
    11461 cgacaatgaa atgtcgattt ccgaaaatgt tggcgcgctc aacaaccatc tggcgcagct
    11521 gctttccggt aagctttact cttcactgcg cgaaggcgga aaaaaagttt tctctggcgt
    11581 gccacccatt aaagagctgc tcaaacgtac cgaagaacat attaaaggca tggtagtgcc
    11641 tggcacgttg tttgaagagc tgggctttaa ctacatcggc ccggtggacg gtcacgatgt
    11701 gctggggctt atcaccacgc ttaagaacat gcgcgacctg aaaggcccgc agttcctgca
    11761 tatcatgacc aaaaaaggtc gtggttatga accggcagaa aaagacccaa tcaccttcca
    11821 cgccgtgcct aaatttgatc cctccagcgg ttgtctgccg aaaagtagcg gcggtttgcc
    11881 aagctattca aaaatctttg gcgactggtt gtgcgaaacc gcagcgaaag ataacaagct
    11941 gatggcgatt actccggcga tgcgtgaagg ttccggcatg gtcgagtttt cacgtaaatt
    12001 cccggatcgc tacttcgacg tggcaattgc cgagcaacac gcagtgacct ttgctgcggg
    12061 tctggcgatt ggaggctaca aacccattgt tgcgatctac tccaccttcc tgcaacgcgc
    12121 ctatgatcag gtgctgcatg acgtggcgat tcaaaagctt ccggtcctgt tcgccatcga
    12181 ccgtgcgggc attgttggtg ctgacggtca aacccaccag ggcgcttttg atctctctta
    12241 cctgcgctgc ataccggaaa tggtcattat gaccccgagc gatgaaaacg aatgtcgcca
    12301 gatgctctat accggctatc actataacga tggcccgtcc gcggtgcgct acccgcgcgg
    12361 caacgcagtt ggcgtggaac tgacgccact ggaaaaactg ccaattggca aaggcattgt
    12421 gaagcgtcgt ggtgagaaac tggcgatcct taactttggt acgctgatgc cagaagcggc
    12481 gaaagtcgct gaatcgctga acgctacgct ggtcgatatg cgtttcgtga aaccgcttga
    12541 tgaagcgtta attctggaaa tggccgccag ccatgaagcg ctggttaccg tagaagaaaa
    12601 cgccattatg ggtggtgcag gcagcggcgt gaacgaagtg ctgatggccc atcgtaaacc
    12661 agtacccgtg ctgaacattg gtctgccgga cttctttatt ccacaaggaa ctcaggaaga
    12721 aatgcgcgcc gaactcggcc tcgatgccac cggtatggaa gccaaaatca aagcctggct
    12781 ggcataatcc ctactctact cctgctatgc ttaagaaatt attcatggca ggagtggcag
    12841 catgcaatac aaccccttag gaaaaaccga ccttcgtgtt tcccgacttt gcctcggctg
    12901 tatgaccttt ggcgagccag atcgcggtaa tcacgcatgg acactgccgg aagagagcag
    12961 ccgtcccatc attaaacgtg cgctggaagg cggcataaat ttctttgata ccgccaatag
    13021 ctattccgat ggcagcagcg aagagatcgt cggtcgcgca ctgcgggatt tcgcccgtcg
    13081 tgaagacgtg gtcgttgcga ccaaagtgtt ccatcgcgtt ggtgatttac cggaaggatt
    13141 atcccgtgca caaattttgc gctctatcga cgacagcctg cgccgtctcg gcatggatta
    13201 tgtcgatatc ctgcaaattc atcgctggga ttacaacacg ccgatcgaag agacgctgga
    13261 agccctcaac gacgtggtaa aagccgggaa agcgcgttat atcggcgcgt catccatgca
    13321 cgcttcgcag tttgctcagg cactggaact acaaaaacag cacggctggg cgcagtttgt
    13381 cagtatgcag gatcactaca atctgattta tcgtgaagaa gagcgcgaga tgctgccgct
    13441 gtgttatcag gaaggcgtgg cggtgattcc atggagcccg ctggcgcggg gccgtctgac
    13501 gcgtccttgg ggagaaacca ccgcacggct ggtgtcggat gaagtgggga aaaatctcta
    13561 ccaagaaagc aatgaaaatg acgcacaaat tgcagaacgc ttaacgggcg tcagtgaaga
    13621 acttggtgca acgcgagcac aagttgcgct ggcctggttg ttgagtaaac cgggcattgc
    13681 cgcaccgatt atcggaactt ctcgggagga acagcttgat gaactgctaa acgcggtgga
    13741 tatcaccttg aagccggaac agatcgccga gctggaaacg ccgtataaac cgcatccggt
    13801 cacaggattt aaataggtat gcaggcctga tgagacgtga caagcgtcac atcaggcatc
    13861 ggtgcacaac tacgacagaa tacccagcgg ccagtgatga ccgataaaat acaggatgcc
    13921 agcggagatc accccggcga caatatcgtc aatcatgatc cccatgccgc catgtacatt
    13981 gcgatcaaac cagcggatcg gccacggctt ccacatatcc agaatacgga aaatcacaaa
    14041 tccggcggta acccactgcc agtcattggt cggcagcgcc atgagcgtaa tccacatacc
    14101 aataaattcg tcccagacaa tactgccgtg atcgtgcacg cccatgtctt tcgccgtttg
    14161 atgacaaaga tagacgccga tacagatccc cagcattacc accagcgaat agagctgcca
    14221 gggcaaaaaa gtcatcagat accagaaggg aatcgccgcc agcgacccca tcgtgccagg
    14281 aacgatcggg cttaatccac ttccgaatcc gacagcaagc agatgccacg gattactcat
    14341 tttcaggcga cttttcgcga catctttatg gcgtggcaaa atggtcatat cctttccagt
    14401 ctaacgtgac aggttcgccg tcacgaataa aacaaagccc ttcgatatcg gcggtcattt
    14461 gcccgataca ggtaaacggt acgcccaggt gtccgagagc cacatccagc gcgccacggt
    14521 tcagttccgg caccgtgaaa cacaactcgt aatcttcacc gccagagagc gcccagcgca
    14581 gcgcctgttc cggttcaaca tggcgagaaa gcgcatcaga aaacggcagc aatgccaggt
    14641 caatacgtgc gccgcagtcg ctggctttca cgatatgccc gagatcggaa atcagaccgt
    14701 cagagagatc gatagctgaa tttgccagat cgcgcagtgc ctgcccctgt aaaatacgcg
    14761 gcgacggacg gagatgacgt ttgatcaagt agtccgcatc tttagcatcg gcaacctgca
    14821 aacggttttg caaaatcgcc agcccggcag cgctatcgcc cggtgtaccg gtcacataga
    14881 tccagtcacc cggtttcgcc ccagagcgcg ttaaggctcg tcccatcgga acaaagccgt
    14941 ggatacccaa cgtcattgat aatggcccac gcgtggtatc gccgccaatg agttgcatat
    15001 cgtaataatt gagaagatca aacaagctgt cgctgaagga ctcaagccac gcttcgtcta
    15061 cgtccggtaa ggttaatgcc agcgtcagcc aggccggatc ggcccccatc gctgccagat
    15121 cgcttaggtt caccgccagt gctttataag ccagatcagc aggatcgata tcagggagga
    15181 agtggttgcc cgccaccagc gtatcagtgc tgatcgccag ggtctgtttc tcagggatat
    15241 tgagaagagc gcaatcgtcg ccgatgccca gttcgacatc aagacgagaa cttcttacac
    15301 ggtcaaaata acgggcaatc agggagaact cgccacatgc catacgttat gcctcagcag
    15361 gtaaaaaaga aaaggccggc gatcatggaa cggtcttccg tgaatctacc ggcctggata
    15421 ttactttttg ttagggcgaa tcacaggtgc tgctttatcg agtacgccgt tgacgaactt
    15481 atggctgtct tctgcgccga acgatttcgc cagttcgatc gcttcgttaa tggccacttt
    15541 gtatggcaca tcgctacgtt tagacagctc gtacagcgca atgcgcagta ctgctttttc
    15601 tacctggccc agttcttcca gcagacggga caggtacggc ttcatcagtc cgtcgaggta
    15661 tgcggtgtta gtcgccaccc cggccagcag ctcacggaag tacaggacgt caacgtcttt
    15721 tacatcctgt tcagccagga actggtattc aacatcagcg atgtcgttct gggacaactg
    15781 ccaggagtag agcgcctgga cggcacactc acgagcgcgg cgacgagcag caggtttcac
    15841 ggatttcccc ttactaattt caggccttga tggctttcaa tacattaatc atttcaagcg
    15901 cggtcagtgc agcttctgca cctttgttgc cagctttggt gccagcacgt tcgatcgctt
    15961 gttcaatgct ttcagtggtc agaacaccaa aagcaaccgg aatttcgctg tcctgggcaa
    16021 catgcgccag gccgttgctt gcaccaccag cgacatattc aaagtgggca gtgccaccac
    16081 gaataaccgt acccagcgca atcaccgcgt cgtatttacc ggttttagcc agtgcacccg
    16141 ccgccagcgg cagctcatag gcacctggca cccaaacaac ggtaatgttt tcatctttta
    16201 cctgaccgat acgtttcagt gcgtcaattg caccttccag caggctgtca ttgataaagt
    16261 tgttgaaacg cgcgatggtg atggcgacgc gagcgtccgg ggtagcaacg ttagcttcaa
    16321 taatgttcat tttcttcctt cgggttcgag tatggccccg caggggggcg gattttagca
    16381 taatatttcg tgcgctgctt ccctttcgag ccgggagatc atgcacccac taaatgcagg
    16441 caaacatccg ggcctacatg acgtatctct ttgaatttaa attggggagc gtcggctaat
    16501 ttctcaagcc ctggcagcgt gcataatcca cgggcgtcgt tgcctaatag tttaggtgcg
    16561 atatagacaa tcagctcatc gactaaaccc gcctgtagca atgcgccagc gagcgttggc
    16621 cccgcttcca cccagatgct gttaatctgc tgtttaccca gttgcatcat tagtacaacc
    16681 agatccaggt gacctttatg ctctggaatc agcaaggtac gcaccgtttc cggccactca
    16741 cgagaatctt cctgcgtacg cgcgaaccag gtttcgccgg gctgctgcac aatgcgatgt
    16801 tccggcgtca cgcgattttg gctatcaatc acaatacgta ccggctggcg gagattttgt
    16861 tgcgggtaga gcccctgagt ttgttcatcc agttcagacc aacgcactgt taaggctgga
    16921 tcatccgcca gcaccgtggc gctgctggtt aaaatggcat gactttgcgc gcgcagtcgt
    16981 tgtacgtcgc gcctcgcctg aggtgaagtg atccactggc tttcgccact cgccatcgcc
    17041 gtgcgaccat caagcgatgc gccaagtttt aactgaatat aaggaaagcc ggtgcgcatc
    17101 cgtttgagaa agcctttatt caattgctca gcttcactca tcatcagccc gtggctgacg
    17161 tcaatgccag cctgttgcag acggtaaagt ccacgtccag cgacctgcgg attggggtct
    17221 tgcattgcag caaccacgcg cgccacgccc gcagcaatta atgcatcaca acacggtggc
    17281 gtacgaccat gatggctaca gggttcgagt gtgacatacg ccgttgcgcc tttggctttt
    17341 tcgccggcca tgcgcaacgc gtgtacctcg gcatgcggct cacccgctcg ttgatggtaa
    17401 ccttcaccga caatttcgcc atctttgaca atgacgcacc cgacattcgg gttgggatgc
    17461 gtggtaaaac gtcctcgttg cgccagcttt agcgcccgcg ccatgtaata ctcgtcctgc
    17521 acggcttagt cctccaggcg cgcgatctct tcgccaaatt ctttgatatc ttcgaaactg
    17581 cggtagacag aggcaaaacg gatataggcg actttatcga gctttttcaa ttgctccatc
    17641 accagattgc caatcatctt gctcggcact tcgcgctcac cggtggcgcg cagctgcgat
    17701 tttatatgat tgattgccat ttcgacgtca tcggaactca ccggacgttt ttccagcgcc
    17761 cgcagcattc cgctacgtaa tttctcttca ttaaacggtt cacgcacgtc gttgcttttt
    17821 acaacacgcg gcataaccag ctccgccact tcaaaggtgg tgaaacgttc attacacacc
    17881 agacactgcc gacggcggcg tacggatgaa ccctcgccca cgagacgaga gtcaattacc
    17941 ttagtgtcca cggcgaaaca gaatgggcaa tgcatacggc gtcctgacca ggtggttaac
    18001 agaaatctat tttaacctga actgacgata caacaaaggc gcaacgcttt tgagataaag
    18061 gatcgatgct ttcactgctt ttaccctcta ccattaggct aattgcgacg agaaagggac
    18121 gacctatgaa tactaacgtt tttcgactgc tcctgctggg aagcctgttc agccttagcg
    18181 cctgtgtgca gcaaagtgaa gtgcgacaga tgaaacacag cgtcagcacg ctgaaccagg
    18241 agatgacgca gctcaataaa gaaacggtca aaatcactca gcaaaacagg ctgaatgcaa
    18301 aatccagcag tggggtttac cttctgcctg gagcaaaaac accagcaaga ctggaaagcc
    18361 agatcggtac tttacgtatg tcgctggtga atattacgcc tgatacagat ggcaccaccc
    18421 tgacgctacg tattcagggc gaatccaatg accctttacc cgcattcagc ggaaccgttg
    18481 aatatgggca aattcaggga acaatagaca actttcagga aatcaatgtg cagaatcaat
    18541 tgattaacgc acctgccagc gtcctcgccc ccagcgatgt tgatattccg ttacagttaa
    18601 agggtatgtc tgtggatcag ttaggctttg tacgtatcca cgacattcaa cctgttatgc
    18661 agtaaacgta ttgcggggcg atattgtgcg tcccgcaaca tctttctccg tcattttgtt
    18721 actccgctta catcacctgg attgatagta aaagtttgca acaagggtga aagtcagtac
    18781 aatccccgcc cgaatgtgtg taaacgtgaa cgcaatcgat tacgtaaatg atagaactgt
    18841 gaaacgaaac atatttttgt gagcaatgat ttttataata ggctcctctg tatacgaaat
    18901 atttagaaac gcaatttgcg cctttttcac tcccgcaagg gattttcaaa cagtggcata
    18961 catatgaaaa aaacattact ggcagccggt gcggtactgg cgctctcttc gtcttttact
    19021 gtcaacgcag ctgaaaacga caaaccgcag tatctttccg actggtggca ccagagcgtt
    19081 aacgttgtcg gaagctatca cacccgtttc ggaccgcagc tccgcaacga tacctacctt
    19141 gagtacgaag cattcgctaa aaaagactgg ttcgacttct atggttatgc ggatgcgccg
    19201 gtattcttcg gcggtaactc cgatgcaaaa ggtatctgga accacggttc tccgctgttt
    19261 atggaaatcg aaccgcgttt ctccatcgac aagctgacca atactgacct tagctttggt
    19321 ccgttcaaag agtggtactt cgcgaacaac tacatttacg acatgggtcg taataaagat
    19381 ggccgccaga gcacctggta catgggtctg ggtaccgaca tcgatactgg tctgccgatg
    19441 agcctgtcca tgaacgtcta tgcgaaatac cagtggcaga actacggcgc agcgaacgaa
    19501 aacgagtggg acggttaccg tttcaaagtg aagtactttg tgccgattac cgatctgtgg
    19561 ggcggccagc tgagctacat cggcttcacc aacttcgact ggggttccga cctgggcgat
    19621 gacagcggtt atgcgaacaa cggtattaaa acacgtacca ataactctat tgcgtccagc
    19681 catattctgg cgctgaatta cgatcactgg cactactctg tcgttgcccg ttactggcat
    19741 aacggtggtc agtggaatga cgatgcagaa ctgaacttcg gcaacggcaa cttcaacgtt
    19801 cgctctaccg gctggggtgg ttatctggta gtaggttaca acttctaatt gtgagaatgc
    19861 cggatttcat atccggcatt ttttatcact tcttcttgtt catcatcgct ttcaaatcag
    19921 cgaatgggtt gtacttcgct tcaccgacat ctttctgcgc atcttcccct gcgataacgg
    19981 tcgtaccata ctgatccgct tcggtgtatt tcgaatgctc atgatcgtgg caatagagac
    20041 aaagtaattc ccagttactg ccatcttccg ggttattagt atggtcgtga tcaatgtggt
    20101 gaacggtaag ttcacgcagg ttggaataaa caaactcgcg ggaacagcga ccgcagaccc
    20161 acggatagat ttttaatgct ttttcgcgat agccgctttc taaccgcgca tagttttttg
    20221 ggatgatagc catgaaaaag ttacctggat gaaatgtagg gttacgcgca gtttcccaag
    20281 atgcggggat tttcgcaatc accttacatc aaaaaaaatc ccgatcttct gaccgggatt
    20341 ttcaacatca gctgaaactt gattaaggca gaattgacgg ctgatccgcc ccttcttttt
    20401 ccactttctg ctgcaacatg tgttcgcgct tcatacccag tttcagagcc agcgcagatg
    20461 ccacatagat ggaagatgca gtaccgatgg aaacaccgat aagcatggtc agcgagaagc
    20521 cttccagtac cggaccaccg aagaggtaca gcatcaggat aaccatcaag gtagtaccgg
    20581 atgtgatcaa ggtacggtgc agcgtctggg tcaaggacac gttaaagatt tcgtaaggcg
    20641 taccgcgacg gatcttgcgg aagttttcac gaatacggtc cgataccacg atactgtcgt
    20701 taagcgagta accgataacc gacatcaacg atgccacaat ggtcaggtca atctcgatat
    20761 ggaataacga caaaataccc agcgtaatga taacgtcgtg cgccagcgca ataacaaccc
    20821 ctgccgccag tcgccactca aagcggaaac ctacgtacac gaggatagac agcagcgccg
    20881 ccatcaacgc catcgcaccg
//
