LOCUS       NZ_CP026498            22601 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. CB01881 chromosome.
ACCESSION   NZ_CP026498
VERSION     NZ_CP026498.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CB01881
  ORGANISM  Streptomyces sp. CB01881
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     A 3-hydroxy-3-methylglutaryl-CoA synthase gene based probe for the
            discovery of the acyltransferase-less polyketide synthases
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2018) Xiangya International Academy of
            Translational Medicine, Tongzipo, Changsha, Hunan 410000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002953255.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 02:39:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,978
            CDSs (total)                      :: 7,904
            Genes (coding)                    :: 7,565
            CDSs (with protein)               :: 7,565
            Genes (RNA)                       :: 74
            rRNAs                             :: 5 (5S)
            complete rRNAs                    :: 5 (5S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 339
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 339
            Pseudo Genes (frameshifted)       :: 124 of 339
            Pseudo Genes (incomplete)         :: 251 of 339
            Pseudo Genes (internal stop)      :: 10 of 339
            Pseudo Genes (multiple problems)  :: 45 of 339
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:44:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 11193708
            Orig. end                         :: 11216309
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026498.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22601
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="45"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22601
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22601
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12601](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12601
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    51..68
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            complement(1056..1700)
                     /locus_tag="C2142_RS38295"
                     /old_locus_tag="C2142_38320"
     CDS             complement(1056..1700)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387254.1"
                     /locus_tag="C2142_RS38295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38320"
                     /product="DNA-binding protein"
                     /protein_id="WP_241003078.1"
                     /transl_table=11
                     /translation="MEVVGVFVTTGQAGTALGCSIPTVKKLMATGVVPGVREQGRQVFP
                     LAALQQLQARPAADLTVLGAPEVAVLRSDAPARVEEPDRDWIGFGAALDQAQLLAALSG
                     WWRCDPARVAAGGVLPVTVASFVVAVLTGLTEWEADGTAGTAGRFRFPKARLAGYLTDL
                     TAPANAADPADPEDVRLAGLLLGTRLASVSGGPIAYVTTTATTDQPATEGE"
     misc_feature    2178..2194
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.82"
                     /tool="antismash"
     gene            2264..2548
                     /locus_tag="C2142_RS38300"
                     /old_locus_tag="C2142_38325"
     CDS             2264..2548
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128105.1"
                     /locus_tag="C2142_RS38300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38325"
                     /product="hypothetical protein"
                     /protein_id="WP_148647374.1"
                     /transl_table=11
                     /translation="MYAAVRRYEGVTDPAEAGRRVAEGFVPILRQVPGFVAYYWVDAGD
                     GVMVSTSVFTEQTGAEESIQRAANFVRDNLASLLPNPPQITAGQVVAAG"
     gene            complement(3205..3414)
                     /locus_tag="C2142_RS38305"
                     /old_locus_tag="C2142_38335"
     CDS             complement(3205..3414)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS38305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_38335"
                     /product="ATP-binding protein"
                     /protein_id="WP_148647376.1"
                     /transl_table=11
                     /translation="MHDRRQLVGNAAKTGCQRKMTVTVEGITDQCVRISVRDGSRTLPC
                     LIDAGPAAESGRGLALVHHLTRGH"
     misc_feature    complement(3514..3529)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.17"
                     /tool="antismash"
     misc_feature    complement(3756..3771)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.89"
                     /tool="antismash"
     gene            4054..5019
                     /locus_tag="C2142_RS38310"
     CDS             4054..5019
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS38310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_153882861.1"
                     /transl_table=11
                     /translation="MHQLLRRSLPALAALGIAVGAPLLTAGTAQAQAEHGCGAVGVQFS
                     VDGGKGWISDGRMSQPHGVIQVRLVGDVVDGCDYRVSLASYDTEGPTWATSGKQTFLGW
                     ATTTLRSGNRQATLDVSAHLPKCYGQIDLYNGDKKFDGVANPAPRYPDGLFPDNLISAW
                     NGGKACVPTPTGTPTVPVPTSSASPTATATPHPTGTPTATTTPSATATATATATATATA
                     TATTSPSTTAKPSASATTGTPSSGTPSTAPAVPAPSAPADTTGPVGKPTANPVSTTPAS
                     TLASTGGNSSQMIVYGAGGAALLALGGGALVIARRRGARR"
     gene            5167..5307
                     /locus_tag="C2142_RS38315"
     CDS             5167..5307
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS38315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_153882862.1"
                     /transl_table=11
                     /translation="MLRTVPVGVAKLEGLEAEAPGADLWWSVADVEAGPGPWWEPTGTR
                     P"
     gene            complement(5394..5753)
                     /locus_tag="C2142_RS38320"
                     /old_locus_tag="C2142_38355"
     CDS             complement(5394..5753)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1164: transposase
                     IS3/IS911 family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /locus_tag="C2142_RS38320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38355"
                     /product="transposase"
                     /protein_id="WP_148647379.1"
                     /transl_table=11
                     /translation="MPAPRKYPDELRERAVREVRSTGRPVAHVARDLGIHKEALRSWVR
                     QAEADAGERGDRLTTAERDELKELRKEVAELRRANDILKAASVFFAQEIDRPRSQSRRP
                     LDHTIADSMKPGAAH"
     gene            complement(6088..7245)
                     /locus_tag="C2142_RS38325"
                     /old_locus_tag="C2142_38360"
     CDS             complement(6088..7245)
                     /EC_number="6.3.2.2"
                     /GO_function="GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042398 - cellular modified amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1165: carboxylate-amine ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010468218.1"
                     /locus_tag="C2142_RS38325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38360"
                     /product="glutamate--cysteine ligase"
                     /protein_id="WP_148647380.1"
                     /transl_table=11
                     /translation="MGTGADTTGGDGRLTLDAGGRPTVGVEEEYLLLDPDSGLPLPYVD
                     AVQEAAGLHPAVHPTELQNELLQAQVEVATPVCRDLAEVGGHLLRLRHALAAAAETADC
                     RLAACGTAPYPPSTPPAIVDAPRYRSIRRNMSRLADEALINGMHVHVAVPDPQAGVEVL
                     NRLRPWLPVLTALSANSPLWYGSDTGYASWRTVVFSRWPISGIPPYFADAEDYERRIAH
                     LLEARLIRDRGQLYWQARLSAKFPTVELRAMDVQLRVDEAVMLAGLVRALVVTAMRQAA
                     AGRPAPERTPESLDGAGWHAARYGMDATLHDPATGLSRPAGELVGSMLAALAPVMDELG
                     DTRAVVPLVDRLLDVGNGAERQRRHLAEHGRSGLIAMIAAESAAA"
     misc_feature    complement(7245..7258)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            complement(<7416..7931)
                     /locus_tag="C2142_RS38330"
                     /old_locus_tag="C2142_38365"
                     /pseudo=""
     CDS             complement(<7416..7931)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010474601.1"
                     /locus_tag="C2142_RS38330"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38365"
                     /product="GNAT family N-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MADRSRSRSTSDEITVHPLAWPPAPIKTERLVLRESEARDRAALI
                     DLFASPEVGTYVGGARRRDELERAMPEVPGQRFGFFVVELDGTTIGMITLDRRDPERKG
                     HLRPEGGEPELGYMFLPQAWGRGYATEACAAALDWFADAHPGEPVALSTQTADESSRRV
                     AAKPGFTEV"
     misc_feature    8182..8191
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.63"
                     /tool="antismash"
     misc_feature    complement(8416..8430)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.11"
                     /tool="antismash"
     gene            8507..9163
                     /locus_tag="C2142_RS38335"
                     /old_locus_tag="C2142_38370"
     CDS             8507..9163
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028922.1"
                     /locus_tag="C2142_RS38335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38370"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_148647381.1"
                     /transl_table=11
                     /translation="MRVRKSAFAALAVTAALSLTACQDDGAGTAQGAPATAPTTSTGAS
                     PSGGPASGGPASGGPGKGSTPPTAAPAGSTGAGKGAKCRTADLTITAADRTITGDADNT
                     VVVELKNHSGKDCTLSGYAGVDLKTSAGTLSAKRSGEPVVAGVVTNGKSTYFGISYPAN
                     TSGGSGVKITGLVVTPPDETQSVTLPWPGTGSLPVTDAGGSPVKIGPMGSAGQGQ"
     gene            complement(<9399..>9771)
                     /locus_tag="C2142_RS41365"
                     /old_locus_tag="C2142_38375"
                     /pseudo=""
     CDS             complement(<9399..9771)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010987360.1"
                     /locus_tag="C2142_RS41365"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="C2142_38375"
                     /product="IS200/IS605 family accessory protein TnpB-related
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLGPPRRFDHHLGGSAGHRDAQLRHALTRLLHRAASTGVRAIASK
                     TSTSPSPGPVRNTVGREVPPAGLRYPHRTPARPSAGHVRRTRPRCDHRRSRLHQQMGSR
                     ASAEAPHRHHQEDHSPRRPG"
     gene            10001..12601
                     /gene="lanKC"
                     /locus_tag="C2142_RS38340"
                     /old_locus_tag="C2142_38380"
     CDS             10001..12601
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="C2142_RS38340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38380"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_148647382.1"
                     /sec_met_domain="micKC (E-value: 3.5e-134, bitscore: 447.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.4e-12, bitscore:
                     43.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDALSDVLADEQFYAPLGTMADPGRRFAPARVAAGWRGSDRDIW
                     TAWSGPGVRRVEQGWKIHVSARLERAQHVLDVVADTCFSEGAPFKHVSAHFFFLALHHK
                     HGARSQSGKFCAVYPPDTPAAERLLALLADALRGEEGAYVLTDRRYRDSRTVHYRYGAF
                     GRRIRLLPDGTAEPLLTDGHGHDVPDLRLPYFVLPEGVSDPFVAQEPAPHRGAIRIRDY
                     EVVKVLQPSNAGGAYQARDTRTGRLVLIKEARPHNGYTWDGVSARERLHREYDTLAAVH
                     AAARGVCPEPLERFTEWEHDFLVMEHVEGLPLVKWINRSSPVLLADRPAADFDRYHADC
                     RRILASLDAALGRLHALGLRFGDVSPGNVIVTPAGDARLVDFESVTGLDARPARMGTPG
                     FAPPPGLAAGHPADPLLADRYGMSALVLTLLAPFHNAPQLTPANFALLRRDLAARAPVP
                     RDLWQRATAFRRTGEDRASTLPGPGEVDADPLGCLTRLAERTASGLLALADTDRPDWAF
                     PPSPQAFHTNTVCVAYGTAGVVHALHRAGLPVPDEVRKRLRKDALAAADALPPGLAVGS
                     AGVGRALARTGHLDEAIDLLRAADGHPLTATTTTLAGGRAGVGLAWLALHRCTRDPRHL
                     ERAAAVGDAILRHGADLGPTLGAHDARGLFHGRSGLALFLHHLTRETGEQRYLAAGRGL
                     LHEELDRAVTLPDGSLSFADNAVNRRVMPYLATGSAGVGTVLLRYATTTADERFTTALP
                     RVVADARKVSAVQAGLHDGFAGLVYLLAEHADFTRDDADRQDALRLATGLLKYAVPHGD
                     DVRWLGTGSLRFSADVASGSAGILLALHRALHGPGDDWFTLDPAHPQESEGNRP"
     gene            12598..12714
                     /locus_tag="C2142_RS38345"
     CDS             12598..12714
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="C2142_RS38345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_194235875.1"
                     /transl_table=11
                     /translation="MTEILALQQLELQTEEAEEASAFPCFSIYASTITESWY"
     misc_feature    12743..12756
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.51"
                     /tool="antismash"
     misc_feature    12743..12757
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 22.44"
                     /tool="antismash"
     gene            12757..12876
                     /locus_tag="C2142_RS38350"
     CDS             12757..12876
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS38350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="class III lanthipeptide"
                     /protein_id="WP_194235876.1"
                     /transl_table=11
                     /translation="MTEILALQQLELQTEEAEEASAFPCFSIYASSFIDTDTY"
     gene            complement(<13375..13494)
                     /locus_tag="C2142_RS41370"
                     /old_locus_tag="C2142_38385"
                     /pseudo=""
     CDS             complement(<13375..13494)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982162.1"
                     /locus_tag="C2142_RS41370"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38385"
                     /product="short-chain dehydrogenase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPRARGRAFLVTGANAGIGYFVVAEQLAGTGATVVLGSRD"
     gene            complement(13643..14500)
                     /locus_tag="C2142_RS38355"
                     /old_locus_tag="C2142_38390"
     CDS             complement(13643..14500)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS38355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_38390"
                     /product="hypothetical protein"
                     /protein_id="WP_148647383.1"
                     /transl_table=11
                     /translation="MPACKPVARLAQALCLGIACLGFSSSPAAAQTAVPCNTGLLAAAI
                     TAANATGDTLVLTSGCTYALNAPLPDITGNVVIDANGSTITRSTWSAFRILVVNPGGDL
                     NLRNAFITNGDGTGTFGGGIANAGTLTVTGSTISNSHADFAGAIGTTYGAHTTIVDSNI
                     VSNLATLNGGGLANDGSTTVIRSHVTGNVAGVQGGGIANTGVLRIQDSEINSNQANTAG
                     GIANFGGGSVDLHQSYVNANTAASAPGGITNVAGSVPLVATDVSGNSPTNCWGSPLFIA
                     GCTG"
     misc_feature    14455..14468
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     misc_feature    14741..14754
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.19"
                     /tool="antismash"
     misc_feature    14746..14759
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.77"
                     /tool="antismash"
     misc_feature    complement(14771..14784)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.05"
                     /tool="antismash"
     misc_feature    14777..14791
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.62"
                     /tool="antismash"
     gene            15559..16536
                     /locus_tag="C2142_RS38360"
                     /old_locus_tag="C2142_38400"
     CDS             15559..16536
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003956067.1"
                     /locus_tag="C2142_RS38360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38400"
                     /product="phosphotransferase"
                     /protein_id="WP_148647384.1"
                     /sec_met_domain="APH (E-value: 5.1e-31, bitscore: 107.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHTQIEVTAELVRHLLRDQHPDLADRPVRLGARGWDNQLWRLGD
                     DLAVRLPWATRSADALLRKEHAWLPALAPHLPLPVPVPQRLGEPSERFPRPWIVTTWVP
                     GEPADRAPATRAADAADALAAFLTALHRPSPAGAPAGRGRGGPLADHAEGFARALASAT
                     EAGLVPDPQAVRIVWEDAVAAPAWTGPPLWLHGDLHPANVLTADGTFCGVIDFGDLCAG
                     DPACDLAAPWILLPDDGVDRFHAAYRPTPDTAALRRARGWAVLRALGGILIGEAGVHGR
                     PGGKATWGPPARAALRRLVATIRRPGGHGQVVRPAHAGQVQPPG"
     gene            complement(16815..17213)
                     /locus_tag="C2142_RS38365"
                     /old_locus_tag="C2142_38405"
     CDS             complement(16815..17213)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004940212.1"
                     /locus_tag="C2142_RS38365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38405"
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_148647385.1"
                     /transl_table=11
                     /translation="MTRYRRLLQQVRNLGRYRSDEEAERVLHAVLSVLGSQLTGEERYD
                     LAQALPEGARAVVASQIPLPQPVAAPAFVEAVARALNTSLTGARWDVSSVLAALDDLAG
                     AHLTDRLLADLPRGYALLFGRADLAAAA"
     gene            complement(17269..17673)
                     /locus_tag="C2142_RS38370"
                     /old_locus_tag="C2142_38410"
     CDS             complement(17269..17673)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735723.1"
                     /locus_tag="C2142_RS38370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38410"
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_148647386.1"
                     /transl_table=11
                     /translation="MTLRWEAFLDKVQERGEYDTPQEAERAARVVLALLGAHLIGEVRA
                     ELAARLPETLALILLSPLQAAEPLTPERFVRATAAWIEGATETTALWDIGAVLSTVADA
                     AGDELTERVLLQLPPGYDLLFGWPQPGHRP"
     gene            complement(18142..18576)
                     /locus_tag="C2142_RS38375"
                     /old_locus_tag="C2142_38415"
     CDS             complement(18142..18576)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140455.1"
                     /locus_tag="C2142_RS38375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38415"
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="WP_148647387.1"
                     /transl_table=11
                     /translation="MLLRTDPFRELDRLTQQFFGTSGTWSRPTPMPLDAYRAGEEYVIC
                     FDLPGVDPEAIDVDVERNMVTVKAERRPRHQSEDVKWELSERPLGVFSRQVMLSDTLDP
                     EGITADYDAGVLTLKIPVAERAKPRKVAVGHNADRKQIQA"
     misc_feature    complement(18671..18691)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.0"
                     /tool="antismash"
     gene            18682..19395
                     /locus_tag="C2142_RS38380"
                     /old_locus_tag="C2142_38420"
     CDS             18682..19395
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090607.1"
                     /locus_tag="C2142_RS38380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38420"
                     /product="hypothetical protein"
                     /protein_id="WP_148647388.1"
                     /transl_table=11
                     /translation="MTTCEKHPKPATKPQTPVGPASFLAAAAALAAIDDAVRTAQAPGA
                     ASPGPSAPPHGPQETDPGQALAALVLLRELRTQLAGWEAGLVENARNAGAAWADLAYPM
                     GVASRQAAENRYLRLRPAGTTHQSAGTGAERVKAVRDRRAADRTVTAWARDNAAELRVL
                     AAQITAVTDLAAEARPAQAALTAALGATDPADLIEPLTAIRPHLGPGQGDLAPRLDALT
                     HRTHQLRDDSNRRRA"
     gene            19370..19501
                     /locus_tag="C2142_RS41885"
     CDS             19370..19501
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS41885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_277347311.1"
                     /transl_table=11
                     /translation="MTATDAGPDRLAAEKRRQELPERLHDLEARVAATTSAAPETAA"
     gene            20170..20493
                     /locus_tag="C2142_RS38385"
                     /old_locus_tag="C2142_38425"
     CDS             20170..20493
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020551507.1"
                     /locus_tag="C2142_RS38385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38425"
                     /product="plasmid stabilization protein"
                     /protein_id="WP_148647389.1"
                     /transl_table=11
                     /translation="MPAGSNKKRERQYEHIKESALDRGENRKRAKEIAARTVNKERARH
                     GESKTASRSSTQDTSSSERGGRRSHSGSEGATYDQLYNEAKKRHVHGRSSMNKKQLADA
                     LGH"
     gene            20561..>20824
                     /locus_tag="C2142_RS38390"
                     /old_locus_tag="C2142_38430"
     CDS             20561..>20824
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.4"
                     /locus_tag="C2142_RS38390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_38430"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_148647517.1"
                     /transl_table=11
                     /translation="MSDPPVVPPERPPLQVTSREATMTTVVCRVEGEADHDTRHLLDAA
                     LAKAVADAPAMLIIDLAPLTFCDSTCLNSLLQAHHDAEAAGVW"
     assembly_gap    20825..21068
                     /estimated_length=244
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(21371..21631)
                     /locus_tag="C2142_RS38395"
                     /old_locus_tag="C2142_38435"
     CDS             complement(21371..21631)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS38395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_38435"
                     /product="hypothetical protein"
                     /protein_id="WP_148647390.1"
                     /transl_table=11
                     /translation="MVSRARGKRRVKPDAGQDEAAGDRSYGDRAAGTGAAQERPDPAAQ
                     DPAVRERYDATADAAQTVRDADEASADGAASGGPEEPPDQP"
     misc_feature    complement(21841..21856)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
ORIGIN
        1 ggaacgcgtc ccggcaggtg gtgacgtcgg cgccgtccgc atcgaaccac tcccccatgg
       61 agcggatctc cgtgaccggg ccgtccgggg cggcggcggg ggcgtagcag ccgaccagct
      121 ggcgctggtg gacgaagtgc ccggccagcc tgtcccggcc cgtgccgacg gcggtggtcc
      181 accgctcgga cggcgtgttc agccaggcgg cgacggcgtc cttgagcgtg ctgtagcgct
      241 cggcgccgtc gtgccacggg gcgccggcgg tgatgtagac ccgctccgcg cccggggccg
      301 tggtgaggac ggcgtccagg atctcccccg gggtgcgggc gccgaggtcg acccggacga
      361 cctggtcgcg gaccgtaagc atcccggccg ccgcgtccag gaacaccgtg gagcgggcct
      421 gctggacgaa gttcgggcgc ttggacacca ggcccgtcgt cacggcctcg aaccgggcac
      481 cgcccgggcc ctccgggaga gacggcagct cgcgcggacc ggcctcgacc accggacccg
      541 gcgcagcaac aaccggagcg gccggggctg gctgctcggc gacggcctgg tcctcgacct
      601 cggccggggc cggggctggc tgctcggcga cggcctggtc ctcgacctcg gccggggccg
      661 gggctggctg cccgggtacg gcggcgggac gggtcagggc cggggcgacc gcggcggcgg
      721 gctcggtgac cggcgcggcc acgggcgcca gagcgggcgc ggcggcagcg gcccggtcgt
      781 cggtcttggc ggcgcggacg gcggccgggg tcgggtccag cagcggggcg atccgcacga
      841 cgtcaccgac cgacagaccc gaggccttcg cgatggcgtc ggccttcgcg ccctcgtacc
      901 ccgccagccc ggccacccgg cgcgagcgct ggacggtgag cttgtccagc tccctctgcg
      961 cggccgcgac cgtcttctcg gcggccgtga tctcggtgcg cagctcgcgc agaccggcga
     1021 gctcggcggt gtacgcctta cggtccatca gcgggtcact ccccctcggt ggcgggctgg
     1081 tcggtggtgg ccgtggtggt gacgtaggcg atcgggccac cggacaccga tgccaggcgg
     1141 gtgccgagca gcaggcccgc cagtcgcacg tcctccgggt cggccgggtc ggcggcgttc
     1201 gcgggggcgg tgagatcggt caggtagccg gccagcctgg ccttcgggaa gcggaaccgg
     1261 cccgcggtgc cggcggtgcc gtcggcttcc cactcggtca ggccggtcag caccgcgacc
     1321 acgaaggagg ccaccgtcac cggcagcacc ccgccggccg cgacccgggc cgggtcgcac
     1381 cgccaccagc cggacaacgc ggccagcagc tgcgcctggt ccagcgcggc gccgaagccg
     1441 atccagtcgc ggtccggctc ctcgacccgg gccggggcgt ccgagcgcag caccgccacc
     1501 tcgggcgcgc cgagcacggt caggtcggcg gcgggccggg cctgcaactg ctggagagcg
     1561 gccagcggga acacctgccg gccctgctcg cgcacgccgg ggaccacgcc ggtggccatc
     1621 agcttcttca ccgtcgggat cgaacacccc agcgccgtcc cggcttgacc ggtcgtcacg
     1681 aacacaccca caacctccat gcctattcac ctaacttgaa atgctatggc gaccctacgc
     1741 ctccccaccg acaccgtcca tgccttttta gtaagtcgta caagcatgcc ttggtcgttg
     1801 tccgtcggaa gcggccagat ccgccaacct gccgctccga cctcctaccg cccgtacggt
     1861 caccacgagt gcggccccaa ccgcacaccc gcagaacagc gagagggaga gtgcgcgtac
     1921 catccccagc caccaacagc cagcagaggg gcctgatcgc gcggttcaag cggtcggagt
     1981 agcgaacggt ctcgaagccg gtcgtcaccc tccacgacgg cgcggcgatg atccttggct
     2041 ccaacaaccg ccttgccgcg gctgatgagg ctcgttgaaa tggctccggc cggagttccg
     2101 tgaagcctcg gttcgtcccg ggcctggagc cggccacagg agctggccgt ggacgccagt
     2161 gcggccatcc gggtgccttc cggatacctc gcaagcggga ggcgcccagt gaggggtatg
     2221 tcgtctcgca cgagatgacc ttgggacctg cgaggagacc agcgtgtacg cagcagtacg
     2281 acggtacgaa ggggtgaccg atcctgcgga ggcaggccgc cgagtggccg agggcttcgt
     2341 gcccatcctt cgccaggttc ccggattcgt ggcctattac tgggttgacg ccggggacgg
     2401 agtgatggtt tccaccagcg tctttacaga gcaaaccggg gccgaagagt cgatccagag
     2461 ggcggcgaac ttcgtgcggg acaacctcgc gtccctgctc cccaaccctc cccagatcac
     2521 ggccggccag gttgtggctg ctgggtagcg acctccgcaa gggccatcac ggaactgcgg
     2581 tcagaaccgt tttcgcagac cctcatcacg gccttcaggc agccggacca taccgggttg
     2641 aagcttgtcc cggttgcagt cggtgccctg ctggcggaac ccgtcctgcg agtgcgccac
     2701 cggaccacgg gagacgatga gagcccggcc tggaccacgt ggaccgcgcc cgtcgtcggg
     2761 tggctggcct actccaacgc gggcaccttg ccactgctcg cagtcggagc ggtcgagtca
     2821 acagcctgga gcctgatcca ccacgacggc gctgccactc gccgtccagg gcgtagacgt
     2881 cctcggagag ccggacgggc ttgccgcacc ggcagcacag gatgcggaac gcgggcacgg
     2941 gcggactcca cctcgacggc gcggggacgg gcggccgggc cgtgtacggg cccggccgcc
     3001 cggggcttca ccgtgcggcg ccccggccgt gggggtgtac gtgccgggcg atgtggagca
     3061 ggcgcagccg cgcgccctgg tctgggcgct cggcggttcc aacgagcgag cgcccggttg
     3121 ggcaacggga agtcagccgg ctgcgatgga gccggtgcgc agatcggcgt ggacggtctt
     3181 gccgtaggtc tccggctcgg cgcctcagtg gccgcgggtg aggtggtgga ccagggccag
     3241 gccgcggccg gactcggcgg cggggcctgc gtcgatcagg cagggcaggg tgcgcgagcc
     3301 gtcgcggacg ctgatccgca cgcactggtc ggtgatgcct tcgacggtga ccgtcatctt
     3361 ccgctggcag ccggtcttcg cggcgttgcc gaccagctgt cggcggtcgt gcaagtcccc
     3421 gcgaaccgcg ctttcgtgtc ggcgcaattc cccacccccg cggtcacgag tccccgtggg
     3481 gacggtgacc atagcccgca tgctcggaca tgatcgaacg cgcatgcgat tagcccccca
     3541 gctgggatgg gccgcgtcag ccgggccgcg agcccgcggg gaaggaaatg caggtgccgg
     3601 cctcgggccg cgcaggcaag atctcggacc ttccgcgcgg ttgcgaccag attcgacaag
     3661 cgcggctacg tccacctcgg cactgtcacc acagccgcgc tcgtcatccg gctccgcact
     3721 ctgccgcctg ttcggcatga agggtgaact cgccccggga caagcattcg aacagttcga
     3781 agccgcccaa cgcaccgacc gacccgcgtg aaccacccag cggggggaac tgcgaggtgc
     3841 atgacgcaaa ctcagctcct tgaactggtc cggctgcagg agagtgcggc tgacttgctg
     3901 ccatgttcac gccctggggt ccggggcttc cgggccatcg ggtacggtca cggtttcacg
     3961 gccgctcagt tccggtgacg gtctgtccgg atcgccacca ggggagcggt gagtcccacc
     4021 cgaaccgtgt acaaccccta gggagcttct ctcgtgcacc aactcctgcg ccggagcctt
     4081 ccggccctcg ccgccctcgg catagccgtc ggcgctccgc tgctcaccgc cggcaccgcc
     4141 caggcccagg ccgagcacgg gtgcggcgcc gtcggcgtcc agttctccgt cgacggcggc
     4201 aagggctgga tctccgacgg ccggatgtcc cagccgcacg gcgtcatcca ggtccgcctg
     4261 gtcggtgacg tcgtggacgg ctgcgactac cgggtctcgc tggcctccta cgacaccgag
     4321 gggccgacct gggccacctc cggcaagcag accttcctcg gctgggcgac cacgacgctg
     4381 cgcagcggga accgccaggc gaccctggac gtctccgccc acctgccgaa gtgctacggc
     4441 cagatcgacc tgtacaacgg cgacaagaag ttcgacggcg tcgccaaccc cgccccgagg
     4501 tacccggacg gcctcttccc ggacaacctg atctcggcct ggaacggcgg caaggcctgc
     4561 gtgccgaccc cgaccggcac gccgaccgtc ccggtgccga cctcctcggc gtcgcccacg
     4621 gccaccgcga ccccgcaccc gaccgggacg cccaccgcca cgacgacgcc ttcggccacc
     4681 gccaccgcga cggccaccgc gacggccacc gccaccgcga cggccaccac ctcgccctcc
     4741 accaccgcca agccgtcggc gtcggccacc accgggacgc cgtccagcgg caccccgtcg
     4801 accgccccgg ccgtgccggc gccgtccgcc ccggcggaca cgaccggccc ggtcggcaag
     4861 ccgaccgcca atccggtctc gaccacgccg gccagcaccc tggccagcac gggcggcaac
     4921 agcagccaga tgatcgtcta cggcgccggt ggggccgcgc tgctcgccct cggtgggggc
     4981 gcgctggtga tcgcccgccg tcggggcgcc cgccgctgag gcacgcagga cgcccgcagt
     5041 ccccggaccg cgggcgtccg tcgtccgttc acccccggac ggtccggaac cggcaccggc
     5101 caggccggct tcgccaaccg cgccgacgac ctcgagcgca ccgcccgcac cccgtacgtc
     5161 gccaagatgc tgcgcaccgt cccggtcggc gtcgcgaagc tggagggcct ggaggccgaa
     5221 gctccgggcg ccgacctctg gtggtcggtc gccgacgtcg aggccggacc gggcccctgg
     5281 tgggagccga ccggcaccag gccctgacca gcaccaccat ccataccttg atgcccgtcc
     5341 ctggctgccg gggcggacgt caagataccc ggaccgggcc ggccgccggg ccatcaatga
     5401 gctgccccgg gtttcatgga gtccgcgatc gtgtgatcaa gcggtctgcg ggactggctc
     5461 cggggacggt cgatctcctg ggcaaaaaac accgaagcgg ccttgaggat gtcgttggcc
     5521 cgcctcaact cggcgacttc cttgcggagt tccttcagct cgtcgcgttc ggcggtggtc
     5581 aggcggtcgc cgcgttctcc ggcgtcggcc tcggcctgac gcacccagga ccgcagggct
     5641 tccttgtgga taccgagatc gcgggcgacg tgggccacgg ggcggccggt cgagcggacc
     5701 tcgcgcacgg cgcgctcacg gagttcatcg gggtatttgc gtggtgctgg cactgctcgt
     5761 ggttctcctt acgcctggat cgtaacaaac ccagacatca gggactccgc gaaagccggg
     5821 acagctcacc ctgaccacca ccacccgcac cttgatgccc gccccggagc ggggcgggcg
     5881 tcaaggtgac cggcgcccct ctcaccaacg ctttgacctg gggcgttatc cggccgcgac
     5941 ttggccgcca aagtatcgga cggatacctt ggcggcccgt caaggcacgg aagggcccgg
     6001 cgcagagacc gtcagggtgg ccggcgaccg gtcagcgcgg agccgcacgg tccacgccgt
     6061 cgggccaccc cgtccaggcc accccgctca ggccgccgcg ctctccgccg cgatcatcgc
     6121 gatcagtccg gagcgcccgt gttccgccag gtgccgacgc tggcgctcgg ctccgttgcc
     6181 cacgtccagc aggcggtcga ccagcgggac caccgcgcgg gtgtcaccca gttcgtccat
     6241 gaccggagcg agcgcggcca gcatggagcc gacgagctcg ccggccggcc gggacagccc
     6301 cgtcgccgga tcgtgcaggg tggcgtccat gccgtaccgg gcggcgtgcc accccgcgcc
     6361 gtccaggctc tccggcgtcc gctccggcgc gggacgtccg gcggccgcct ggcgcatcgc
     6421 cgtgacgacc agcgcgcgca ccagcccggc cagcatcacc gcctcgtcga cgcgcagctg
     6481 gacgtccatc gcgcgcagct cgacggtcgg gaacttcgcc gagagccggg cctgccagta
     6541 cagctgtccg cggtcgcgga tcagtcgggc ctccagcagg tgggcgatgc ggcgctcgta
     6601 gtcctccgcg tccgcgaagt acggcgggat cccgctgatc ggccagcggc tgaagaccac
     6661 cgtgcgccaa ctcgcgtagc cggtgtcgga gccgtaccac agcggcgagt tggccgacag
     6721 cgctgtcagc accggcagcc agggccgtag gcggttcagc acctcgacgc ccgcctgcgg
     6781 gtcgggcacg gccacgtgca cgtgcatgcc gttgatgagc gcctcgtcgg ccagccgcga
     6841 catgttccgc ctgatggagc ggtaacgcgg ggcgtcgacg atcgccgggg gcgtggaggg
     6901 ggggtacggg gcggtgccgc aggcggcgag ccggcagtcg gcggtctcgg cggcggccgc
     6961 gagcgcgtgc cgcaggcgca gcagatggcc gccgacctcg gcgaggtccc ggcagaccgg
     7021 ggtggccacc tccacctgcg cctggagcaa ctcgttctgc agctcggtgg ggtgcacggc
     7081 ggggtgcagc ccggccgcct cctgcaccgc gtcgacatac ggcagcggca gaccgctgtc
     7141 cgggtcgagc agcaggtact cctcctcgac gccgaccgtc ggacggccgc ccgcatccag
     7201 ggtgagccgg ccgtcaccgc ctgtcgtgtc ggcgccagtg cccataactc agggttaccc
     7261 gcccatctgg tggccaaccg gggcaccggc ggtacccgac cgtgccggac gggccggccc
     7321 gggaccaggc cgtggaagca ggcacttttg gcccggaaac gggctgcacg ggcaggttcg
     7381 gccgcccggg tcgtagctgc ctcgcagtcg gcgtgcacct cggtgaaccc cggcttcgcc
     7441 gcgacgcgcc tcgaggactc gtcggcggtc tgggtggaga gcgccaccgg ctcaccggga
     7501 tgcgcgtcgg cgaaccagtc gagcgccgcc gcgcatgcct cggtggcgta cccgcgtccc
     7561 cacgcctgcg gcaggaacat gtagccgagc tcgggctcgc cgccttccgg acggaggtgg
     7621 cccttgcgct ccgggtcgcg ccgatcgagc gtgatcatgc cgatcgtcgt tccgtcgagc
     7681 tcgaccacga agaagccgaa gcgctgcccg ggcacctcgg gcatcgcgcg ctcgagctcg
     7741 tcacgccgcc gagcgccgcc gacgtaggtg cccacctctg gtgaggcgaa caggtcgatc
     7801 agcgccgcac ggtcccgggc ctcggactcg cggagcacga gccgctcggt cttgatcggg
     7861 gcaggtggcc aggcgagggg gtgcaccgtg atctcatccg acgtggaacg gctcctactc
     7921 ctatcggcca tgcgcggttc ggccccgtac ggccgttggg ggcagcgacg tctgacgtcg
     7981 ccgcacatcg agacgcgctc cgacgagatg ccagttgcgt gcgcccggaa agatccgccg
     8041 ggcaggagcc tcagacgacc gacagcggca gcggcggcag cagcggcttc tgacccgtcg
     8101 gcccgatctg gaggtccgtc tgcatcagcc cacccatcag atccgtgacc acggcccgtt
     8161 gtcccccttc ggtgacaacg cttttttgtg acgctcccgc tggggctggg cacgtcacac
     8221 tgtcgtggtc gcggtctggg gtcaaggtcg tccaggtcac gggtctgtac cggcggtcgg
     8281 cgccggcggt gcgcgggggc gcggtggacc ggcgtccggg caggtcggcg gcagggtgcg
     8341 gcagggcacg gcgggcgagg gcgcgggtgg ttcgcggccg tacatgtcac agcactgtcc
     8401 tgggagcggc ccgggcgcaa cggttcgtcc gggagggcgg tcccggtctt cggaaacccg
     8461 ctcgcaccga gcaccaggca ccgccgcccc ctccggagga aacaccgtgc gcgtccgcaa
     8521 gtccgccttc gccgccctgg ccgtcaccgc cgccctctcg ctcaccgcct gccaggacga
     8581 cggggcgggc accgcacagg gcgccccggc caccgccccg acgacgtcca ccggcgcctc
     8641 ccccagcggc ggtccggcct ccggcggacc ggcttccggc ggtccgggga agggcagcac
     8701 gccgcccacc gccgcaccgg ccggctccac cggggccggg aagggcgcca agtgccggac
     8761 cgcggacctg accatcaccg ccgcggaccg caccatcacc ggcgacgccg acaacaccgt
     8821 cgtggtcgag ctgaagaacc acagcggcaa ggactgcacg ctctccgggt acgcgggcgt
     8881 cgacctgaag acctccgcgg gcacgctgtc cgcgaagcgc tccggcgagc cggtcgtcgc
     8941 gggcgtcgtg acgaacggca agtcgaccta cttcggcatc agttacccgg ccaacacctc
     9001 gggcggctcc ggcgtcaaga tcaccggcct ggtggtgacc ccgccggacg agacccagtc
     9061 ggtcaccctg ccctggccgg gcaccggctc gctgcccgtc acggacgccg gcggatcccc
     9121 ggtgaagatc ggcccgatgg gatctgccgg ccagggccag tgacccgacg ccccttccga
     9181 gcccccagcg gcctccgggg cgacgggtcc actggcggct gcctggaggc cgtactccca
     9241 ggtgctctcc accctgggga cgctgccgca gtcggcgcag gccaggctcc gcgtcagctc
     9301 gcggtgggcc tggcgggcct tcttctcccg ctccttctgg cgctggtcgt aggcggcgcg
     9361 gttgttcggg tcgtccagcg cctcgaccag ggagtgccgg ccggggcggc gtggcgagtg
     9421 gtcttcctgg tggtgtcggt gaggggcttc tgccgatgct cggctcccca tctgctggtg
     9481 caggcgggat cgacggtgat cacagcgagg tcgtgttcgg cgcacatggc cagcagacgg
     9541 gcgcgcaggc gtccggtggg ggtaccggag accagccggc ggaacttctc ttccgaccgt
     9601 gtttctcacg gggcctggag acggcgaagt cgaggtcttc gacgcgatgg ccctcacgcc
     9661 cgtgctggcg gcccggtgga ggagccgggt gagggcgtgg cgcagctgcg cgtcccggtg
     9721 gccggccgag ccgccgaggt ggtggtcgaa acgcctgggt gggccgagag gcggtgccgg
     9781 ctggacaggc gctcccatac cgcggctgaa ccgttgtcga acccgccgcg cctaacgtcc
     9841 tgtccgtcgg ggcgagggcc gttccggaga gcgggacgag gcgggcccgg cggtccgccg
     9901 gctctccggc acgccgttgc ccgcgtcgtg cccgagggac ggccacgccc gtcggcggcc
     9961 ggtcccgggc ggacgaacga ccacgtggag gagacccccc ttgttcgacg cactgtccga
    10021 tgtcctcgcc gacgagcagt tctacgcgcc gctcggcacg atggccgacc ccggtcggcg
    10081 cttcgcgccc gcccgggtcg cggccggctg gcgcggaagc gaccgggaca tctggacggc
    10141 gtggagcggc cccggggtcc gccgtgtcga gcagggctgg aagatccacg tgtcggcacg
    10201 gttggagcgg gcccagcacg tgctcgacgt ggtggcggac acgtgcttct ccgagggagc
    10261 accgttcaag cacgtgtcgg cgcacttctt cttcctcgcc ctccaccaca agcacggcgc
    10321 ccggtcccag tcgggcaagt tctgcgccgt gtacccgccg gacaccccgg ccgccgaacg
    10381 gctcctcgcc ctcctcgccg acgccctgcg cggcgaggag ggcgcctacg tcctcaccga
    10441 ccgccgctac cgggactccc ggacggtcca ctaccgctac ggcgcgttcg gccgccgcat
    10501 ccggctgctg cccgacggca ccgcggagcc gctgctgacg gacggccacg ggcacgacgt
    10561 gccggacctg cggctgccgt acttcgtcct gcccgagggc gtcagcgacc ccttcgtggc
    10621 ccaggagccg gccccgcacc ggggcgcgat ccgcatccgc gactacgagg tcgtcaaggt
    10681 gctgcagccg agcaacgccg gcggcgccta ccaggcccgc gacacccgca ccgggcgcct
    10741 cgtcctcatc aaggaggcac gcccgcacaa cggctacacc tgggacggcg tgagcgcccg
    10801 ggagcggctg caccgggagt acgacaccct ggccgccgta cacgcggcgg cccggggcgt
    10861 gtgccccgaa ccgctggagc ggttcaccga gtgggagcac gacttcctcg tcatggagca
    10921 cgtcgaggga ctcccgctgg tgaagtggat caaccgctcg tcgcccgtcc tgctggccga
    10981 ccggcccgcc gcggacttcg accggtacca cgccgactgc cgccgcatcc tcgcctcact
    11041 ggacgcggcc ctgggccgac tccacgcgct gggactgcgg ttcggcgacg tcagccccgg
    11101 aaacgtcatc gtcacccccg ccggggacgc caggctcgtc gacttcgagt ccgtgaccgg
    11161 gctggacgcc cgccccgccc ggatgggcac cccgggcttc gcaccgcccc cgggcctggc
    11221 cgccgggcac cccgccgacc cgctcctcgc cgaccgctac ggcatgtcgg ccctcgtgct
    11281 caccctgctg gcgcccttcc acaacgcgcc ccagctgacg ccggccaact tcgccctgct
    11341 gcggcgcgat ctggcggcga gggcgccggt gccgcgcgac ctgtggcaac gggccaccgc
    11401 cttccgacga accggcgagg accgggcgtc gacgctgccc ggccccgggg aggtggacgc
    11461 cgatccgctg ggctgcctga cccggctcgc cgagcgaacg gcctcgggac tgctcgccct
    11521 ggcggacacc gaccggcccg actgggcctt ccccccgtcg ccccaggcgt tccacaccaa
    11581 cacggtgtgc gtggcgtacg gaacggcggg cgtggtgcac gccctgcacc gggccggcct
    11641 ccccgtcccc gacgaggtcc gcaagcggct gcgcaaggac gcgctcgccg cagcggacgc
    11701 gctgcccccc ggactggccg tcggctcggc cggcgtcggg cgggcgctgg cccggaccgg
    11761 gcacctcgac gaggcgatcg acctgctgcg cgcagccgac ggccatccgc tgacggccac
    11821 cacgaccacg ctggccggcg gacgggccgg ggtgggcctg gcctggctcg ccctgcaccg
    11881 gtgcacccgc gacccccgtc acctggagcg ggcggccgcc gtcggcgacg cgatcctgcg
    11941 gcacggcgcg gacctggggc cgaccctcgg cgcccacgac gcccgcggcc tgttccacgg
    12001 ccgctccggg ctggcgctct tcctccacca cctcacccgc gagacggggg aacagcgcta
    12061 cctggcggcg ggtcgcggac tgctccacga ggagctggac cgcgcggtga cgctgcccga
    12121 cggctccctc tccttcgccg acaacgccgt gaaccggcgc gtcatgccct acctggccac
    12181 cgggtccgcc ggtgtcggaa ccgtcctgct gcgctacgcc accaccaccg cggacgagcg
    12241 cttcaccacg gccctgcccc gcgtcgtcgc cgacgcccgc aaggtcagcg cggtgcaggc
    12301 cggcctgcac gacggcttcg ccggactggt ctacctgctc gccgaacacg ccgacttcac
    12361 ccgggacgac gccgaccgcc aggacgcgct ccggctcgcg accgggctcc tcaagtacgc
    12421 cgtcccgcac ggcgacgacg tccgctggct cggcacgggc tcgctccggt tcagcgccga
    12481 tgtggccagc ggcagcgccg ggatcctgct ggcgctgcac cgagccctcc atggcccggg
    12541 tgacgactgg ttcaccctgg atcccgccca cccacaggaa agcgaaggca accgtccatg
    12601 accgagatcc tcgccctcca gcagttggaa ctccagaccg aggaggcgga ggaggcgtcc
    12661 gccttcccct gcttcagcat ctacgccagc accatcaccg agtcctggta ctgatcgcca
    12721 ccgtccgccg accccgtccc aaggaagaag cgttccatga ccgagatcct cgccctccag
    12781 cagttggaac tccagaccga ggaggcggag gaggcgtccg ccttcccctg cttcagcatc
    12841 tacgccagct cgttcatcga caccgacacg tactgacccc ggccgggaag ggaacggccc
    12901 cgtgaccggg atcctcgccc tccagcggct ggaggccgac cccgacgcga actacccgtg
    12961 cctcagcatc ttcgccagcc actactacga aacgctgtag aacccggctg accgaccact
    13021 cccccgccac ggaccggcgg gccggcaggc catcgcaaac cgcctgccgc cgagcagggc
    13081 cgacaccgtg gcccgcggtc accggtggtc ttcgttcgtc gacacgactc acgaagacca
    13141 ccggtggccg ccccgcgaac agaccggccc agcacgccgt ccgcgacacc ttcacccccc
    13201 acccgcacca cacctcgccc gcacgggccc ggtcgaccaa ctgcccgatc aactgggcgt
    13261 ccagcagatc cgccgacagc tcgaccggcc ggacctcttc aaccgcctcg gcagagacag
    13321 tcatgtcgct cctcaggtgc tgcttccgtg atcggaagtc accccgatcg cccggtcgcg
    13381 gctgccgaga acgaccgtgg ccccggtgcc ggccagctgc tcggcgacga cgaagtaccc
    13441 gatgcccgcg ttggcgccgg tgaccaggaa ggcccttccc cgggcacgag gcagccggtg
    13501 aacctcccgt tgcgggggct ggggcgggct cccggaagct cggcgtggtc tcgaggggag
    13561 cgggcccgcc ccttcacagc cggccgggcc cggtccctac ggtcccgggg ccactcgaca
    13621 tgaccgtccc cgggcttccg cgtcagccgg tgcagccggc gatgaaaagc ggactgcccc
    13681 agcagttggt aggcgagttg ccactgacat cggtggcgac cagggggacg ctgccggcga
    13741 cgttcgtgat gccgccggga gcgctcgccg cggtgttcgc attgacgtag gactggtgga
    13801 ggtcgacgga tccgccgccg aagttggcga ttccgccagc ggtgttcgcc tggttgctgt
    13861 tgatctcgct gtcctggatc cgcaggacgc cggtgttggc gatcccgcct ccctgcacgc
    13921 cggccacgtt gccggtgacg tggctgcgga tgacagtcgt gctgccgtcg ttggccagac
    13981 ccccgccgtt cagcgtcgcc aggttgctca cgatgttgct gtcgacgatg gtggtgtgcg
    14041 ccccgtaggt ggtgccgatg gcgcccgcga agtcggcgtg gctgttgctg atcgtgctgc
    14101 ccgtgacagt gagagtcccc gcgttggcga ttccgccgcc gaaggtgccg gtgccatcgc
    14161 cattggtgat gaacgcgttc cgcaggttga gatccccacc cggattgacg acgagaatac
    14221 ggaacgccga ccaggtcgac cgggtgatcg tgctgccgtt ggcgtcgatg acgacgttcc
    14281 cggtgatgtc cggcaacggt gcgttcaggg cgtaggtgca gcccgaggtg aggacgagag
    14341 tgtcgcccgt ggcattggcg gcggtgatcg ccgccgcgag gagacccgtg ttgcacggga
    14401 cggccgtctg tgcggcagcc ggggaactgg agaagccaag gcacgcgatg ccgaggcaca
    14461 gagcttgcgc cagacgcgct acgggcttgc aagcaggcat atctgctcct tcggaaggcg
    14521 agcgggggct cgctgttcgt cccggtcatg ggcatgcggg gatgacgccc tgtccgagag
    14581 gaccgggcga ggcattcctc tgcccctggg gagagcgagc cactgctggc gcacgtcttc
    14641 gcccgcgttg ccgcgctcac gcatccacag cagcacaaag ccgcctactc ggggaagcag
    14701 atcttcggaa gtgaccgtaa ctcggggcga agaaaccgag attcgccaac aaaagttcgc
    14761 caactaacac ttttagtacg caatatgagg tcgcgccacg aagccgcccc ggcctgacgg
    14821 acgccgatgg gcttgcgagc catgtggccg cgcagagcac tctatgtggt gcttcgggcg
    14881 cggcaccgct cgaacccgac cgggccaagc accaggaaac aggtcgatcg tctctgccac
    14941 gaggcggggc aggcgaccga cggacagcgc gaggaaccgt tcaaccccga cggcatgact
    15001 acggcggccg acgccgatgc gccaccccca cccggccggc ctgtccgtgc aagacatcgg
    15061 agatcactgc gcctcccccg gccatcggga catcgggcag caaccgtccg acggaaaaag
    15121 cggagagtcg gtgtacggct cgacaaaagt ccactgcacc aactccattg acgcctgcgc
    15181 cattaaagcc cgcggtacgg accggtcccg cccgcacccg cttcgaggag gaaggcccgg
    15241 tggtccggcg ggacacggac gccttgggtg cgacgggccg tcaggagccg ctgcggaccc
    15301 cggggagggc gcccgggtca cccgtagagg gtgtacatgc tcccgtcctc gacggcctgg
    15361 aaccaccacc actcccgccc ctgctccgcc gccgggcccg caccgcctac cccgaagggg
    15421 gttaccggcc cgtgccgtag cggagcccgt cgaggagcag gtcgaggagg cggtcggccc
    15481 gctggcgctg ggcgggagtg ctggtgacca gtgcgacgcc gctgagaacg aaccgctgcc
    15541 cgactaccgt tgctctgcat gacccacacc cagatcgagg tcacagcgga gttggtccgc
    15601 cacctgttgc gtgaccagca tcccgacctg gccgatcgcc cggtgaggct cggggcgcgt
    15661 ggttgggaca accagctgtg gcggcttggt gacgacctcg ccgtccggtt gccctgggcg
    15721 acgcggtccg cggacgcgct gcttcgcaag gagcacgcct ggctgcccgc ccttgccccg
    15781 cacctgccgc tgccggtccc cgtcccgcag cgcctcggcg agccctccga gcggtttccg
    15841 cggccttgga tcgtcaccac gtgggtgccg ggcgagcccg ccgaccgcgc ccccgccacg
    15901 cgcgctgcgg atgcggccga cgctttggct gccttcctga cggctcttca ccgcccctct
    15961 cccgccgggg cgcccgccgg ccgtggccgc ggggggccgc tggccgacca cgccgagggg
    16021 ttcgccaggg cgctcgcctc ggccaccgag gcggggctgg tccccgatcc gcaggccgtc
    16081 cgcatcgtct gggaggacgc cgtcgccgca cccgcgtgga cgggcccgcc cctgtggctc
    16141 cacggtgacc tgcacccggc caacgtcctc accgccgacg gcaccttctg cggcgtgatc
    16201 gacttcggcg acctctgcgc cggcgatccg gcctgcgacc tcgccgcgcc gtggatactg
    16261 ctgccggacg acggcgtcga ccgcttccac gcggcctacc ggccgacccc ggacaccgcg
    16321 gccctgcgcc gcgcccgcgg ctgggcggtg ctgcgcgccc tcggcggcat cctcatcggg
    16381 gaagcaggcg tccacggccg ccccggcggc aaggccacct ggggcccacc cgcccgcgcc
    16441 gcgttgcgac gactcgtcgc aacgatccgc cgacccggtg ggcacggcca ggtggtcagg
    16501 cccgcgcacg ccgggcaagt ccagccaccc ggctgagcgc cccgatcccc ggcacacagg
    16561 accaacgcca cgaagcccac gccggcaatc gcgacggcac taccggatgc cgccggtgac
    16621 cagacgaccg ggcgtcgcga gtgcgggtcg acgacggggc cgggtgcccc cctgagccgc
    16681 cgaaggcagg tgcgtgctgt cgccgaccca ccggacatcg ggcccggtcg cggtgaagtc
    16741 gcgtccgatc aggtccggta ccggggcgtt cctgtcctgg gcggtggttc gccccggtga
    16801 gcgcccgcgc cgggtcatgc cgcggcggcc aggtcggcgc ggccgaacag gagcgcgtag
    16861 ccgcggggca ggtcggcgag gaggcggtcg gtgaggtggg cgccggcgag gtcgtcgagg
    16921 gcggccagga cggaggagac gtcccagcgg gcgccggtga ggctggtgtt cagggcgcgg
    16981 gcgacggctt cgacgaaggc gggtgcggcg accggctggg gcagcgggat ctgcgaggcg
    17041 acgacggcgc gggccccctc cggcagggct tgggcgaggt cgtagcgctc ctcgccggtg
    17101 agctggctgc cgaggacgga aaggaccgcg tggaggacgc gttcggcttc ctcgtcactg
    17161 cggtagcggc cgaggttgcg gacctgctgg aggaggcggc ggtaccgggt catggcgggg
    17221 gccttccggg gcgggccggc cggtcggcgc ggcggcagtg ggcggttttc aggggcggtg
    17281 gccgggctgg ggccagccga acaggaggtc gtagccgggc gggagctgga gcaggacgcg
    17341 ctcggtgagc tcgtctccgg cggcatcggc gacggtggac aggacggcgc cgatgtccca
    17401 cagggccgtg gtctcggtgg ctccctcgat ccaggccgcg gtcgcgcgca cgaaccgctc
    17461 gggggtgagc ggttcggcgg cctgcagcgg gctgagcagg atcagggcaa gggtctcggg
    17521 caggcgggcg gccagctcgg cgcgcacctc gccgatcagg tgtgcgccga gcagggccag
    17581 cacgacgcgc gccgcccgct cggcctcctg gggtgtgtcg tactcgccgc gttcctgaac
    17641 cttgtccagg aacgcctccc atcgaagagt caccgtggtt tctcctccgc ggcatgggtc
    17701 ggcacgaacg ccgccggtgc cggtcaggac tccgcggcca ggcgccggtg cagaccggtg
    17761 agcttgagta gccgaacccc acagcggccg gccccgtgca ggaccaggcg cgccgccccg
    17821 gtcggccagg tcgcgggcat ggacgggggg tgcccttgcc cgcgcggccc gtggacgtca
    17881 cctccgacgg gtcgagcacc acctcgcggt actcggccgg cgcgggtccg gcttccgcgg
    17941 caggcgcggg gcggtggcga ggccgatccc gccacgcgcc cgtaccggga acgcaaccgg
    18001 tcctggcctg gcacggggct gcccgcggtc cggccggccc gcgcgcggcg ggcgggctcg
    18061 gggagcgagg gcggcggtgg tgtcccgcgc cgccccgtcg gggggatttt cggggcggtg
    18121 cgggacggct tcgggggcgg gtcaggcctg gatctgcttg cggtctgcat tgtgaccgac
    18181 ggcgaccttg cggggcttgg ccctctccgc gaccgggatc ttgagggtca gcacgcccgc
    18241 gtcgtagtcg gcggtgatgc cctcggggtc gagggtgtcg gagagcatga cctggcgcga
    18301 gaagacgccg agcgggcgct cggacagctc ccacttcacg tcctcgctct ggtggcgcgg
    18361 acggcgctcg gccttgacgg tcaccatgtt ccgctcgacg tcgacgtcga tcgcctccgg
    18421 gtccaccccg ggcaggtcga agcagatcac gtactcctca cccgcgcggt acgcgtccag
    18481 cggcatcggc gtgggacgcg accacgtgcc gctcgtgccg aagaactgct gggtcagccg
    18541 gtccagctcg cggaacgggt cggtgcgcaa cagcatcgcg aaacacctcc aagtgggatc
    18601 aaagggtgcc agtgcgcttt cacctgacac cgttctaaca cgtcatccat ccgatgacaa
    18661 acccagccag tcatcgttag agtgacgaca tgtgagaagc accccaagcc cgccaccaag
    18721 ccgcagacgc ccgtcggccc ggcctccttc ctcgccgccg ccgcggccct ggccgccatc
    18781 gacgacgccg tccgcaccgc ccaggccccc ggggccgcct ccccgggccc gagcgccccg
    18841 ccccacggcc cccaggagac cgaccccgga caggccctgg ccgccctggt cctgctgcgc
    18901 gaactgcgca cccagctcgc cggctgggag gcgggcctgg tcgagaacgc ccgcaacgcc
    18961 ggcgccgcct gggccgacct cgcctacccc atgggcgtcg ccagccgcca ggccgccgag
    19021 aaccgctacc tgcgcctgcg ccccgccggg accacccacc agagcgccgg gaccggagcc
    19081 gaacgcgtca aggccgtccg cgaccgccgc gccgcggacc gcaccgtgac cgcctgggcc
    19141 cgcgacaacg ccgccgaact gcgcgtcctc gccgcccaga tcaccgccgt gaccgatctg
    19201 gcagccgagg cccgccccgc ccaggccgcc ctcaccgccg ccctcggtgc caccgacccc
    19261 gccgacctca tagagcccct caccgccatc cgcccccacc tcggccccgg ccagggcgac
    19321 ctcgcccccc gcctcgacgc cctcacccac cgcacccacc agctccgcga tgacagcaac
    19381 cgacgccggg cctgaccgcc tcgccgccga gaagcgccgg caggagctcc cggagcgcct
    19441 ccacgacctc gaagcacgag tggccgccac cacgagcgcc gcgccggaaa cggcggcctg
    19501 agccggcccg aggcgcagcc cgccgggtcc cgggggacgc caggggcgtg gtccgcgggg
    19561 cgggcggccg gcaacgccga gccgcggcgc tgctgctctg cccggggccc gggggtgctg
    19621 gggcggggcc gccggggcgg aacgccagac ccgccgatcg gcggtcgcca ggggttgggc
    19681 ctgcggtctt tcgacgccgg ccgccggctg cgcaacaagc tcccgcacgg cgagccgacc
    19741 ggctccgcca tgcctgcggg gtgggccgtg gacctggtgc gtgccgcgtt cgacgccgcc
    19801 gggccgccgt acccggcgcc cgccggtcca gcgcccgatg tggcggggcc ggggcgtttc
    19861 gacgctgcgg ctcgtacgga tggcttgccg aggcacggga ccgcccgcac cgggaggcaa
    19921 cgaccgcggt gcgggcgagg cctgaatggc tccgactggc acaccgggcg gctgtaccgc
    19981 ccggtctctc cagcgtacgt ccgcggcccg gggccagggc cggtcgtcgt ggtggccgcc
    20041 ggacctgcac gtcagcgggg gttgaccggc ccacaggagg gtgcggtgcg ccgttccgcc
    20101 gtccgtgtct tgggaaggcc gtgccgggta agcgccgccg tgaggtacga gaacgtccga
    20161 ggaggagcca tgcctgccgg ctcgaacaag aaacgcgaac gccagtacga gcacatcaag
    20221 gagagcgccc tcgaccgcgg ggagaaccgg aagcgggcga aggagatcgc cgcccgcacg
    20281 gtgaacaagg aacgcgcccg gcacggcgag tcgaagaccg ccagccgctc ctccacccag
    20341 gacacgtcct cctccgagcg cggcggccgc cgctcccact cgggctccga aggcgccacc
    20401 tacgaccagc tgtacaacga ggccaagaag cgccacgtcc acggccgctc ctcgatgaac
    20461 aagaagcagc tcgccgacgc gctcggccac tgacgacagc cgcaggacca cgagagggac
    20521 gagcgaagag ggtcagccac cccgacgaag ggagccgcgc atgtccgatc ccccggttgt
    20581 gccgcccgag cggccaccgc tgcaggtcac cagccgcgag gccacgatga ccacggtggt
    20641 ctgccgcgtc gagggagagg ccgaccacga cacccgacac ctgctcgacg cggccctcgc
    20701 caaggccgtc gccgacgccc cggcgatgct gatcatcgac ctcgcaccgc tcaccttctg
    20761 cgactccacc tgcctgaatt ccctcctcca agcccaccac gacgccgaag ccgcaggagt
    20821 ctggnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21061 nnnnnnnntt ccctcctccc accacgacgc cgaagccgca ggagtctggc tcgtcctcgt
    21121 cggcgccagc ccccagctcc tccacctcat ggcgctcacc ggcaccgacg agatcttcac
    21181 cctccgcccc cacctgcgtg ccacgcggcc gccccgctcc ccatgaacca cccgatgaaa
    21241 ccgccggccc gctacgcggt caccccggcg ggcaccgcgg atcacacgca ccacccgagg
    21301 tcgccgtcgc ccgcttcacc ggccgccgca cccccgacgg cccaccgctc cacgccgacg
    21361 gcgccggccc tcagggctgg tcgggcggct cctcgggacc gccggaagcg gcgccgtccg
    21421 ccgacgcctc gtcggcgtcg cggacggtct gggcggcgtc ggcggtggcg tcgtaccgtt
    21481 cgcgcaccgc tgggtcctgt gccgcaggat cgggacgctc ctgcgccgct ccggtgccgg
    21541 ccgcacggtc cccgtacgac cggtcccccg cggcctcgtc ctggccggcg tccggcttca
    21601 cccggcgctt gcccctcgct ctggagacca cctgttcctc cccgataccc ggtccacggt
    21661 gttggcaggg ccctcgcatc acacggtacg aggccggtcg gcggcgacgg tccaggcacg
    21721 cggcgcgccg ggctcgcgac gacacgtccg gcggtgcacg tcgtaccgcc gcactcgcgg
    21781 cccccgacga ggcacgggtc cgcaggttcc cgtgccccgt cgacgggtag ccgccggagg
    21841 tgctcaccat cggcgtcgag gaggaatacc tcctcatcga ctcggtgacc ggtatgcccg
    21901 tcacccgcgc ggcccgggtc cgcagcgccg ccgggctcca gccggctctg ggagacgacg
    21961 aggtccagcg ggagctgagc caggcccagc tggaggttgc caccccggtc tgccggaccc
    22021 tggatgaggt cggcggtcac ctgctgcgcc tgcgccacac cctggcgcag gcggccgagg
    22081 actgcgggtg ccggctggcc gccaccggat ccgccccctt caccgaccgc ctggcggttc
    22141 ccatcacacc gaccccgcgc taccggcgga tgcgccgaca ggccgccgca gtcgccgacg
    22201 aacagctcat caacggcatg cacgtccacg tcggcgtccc cgaccgggac gcgggcgtca
    22261 ccgtcctcga cgcgctccgc ccctggcttc ccctgttgat cgcgctgtcc gcgaactccc
    22321 cgctgtggca aggacgcgac accggcttcg ccagctggcg caccgtcgtc ttcgaccgct
    22381 ggcccgtgtc cgggctgccg ccccacttcg ccggcgccgc cgactacgac cggcgtaccc
    22441 gccgcttgct cgccgccggc ctgatcgacg acaccggcca ggtgtactgg caggcccgcc
    22501 tgtccgaacg gtatccaacc atcgaggtac gggccatgga cgtccagctc cgcgtcgacg
    22561 aggccgtcct gatcgccggc ctcgtccgtg ccctcgccgt c
//
