LOCUS       NZ_CP026498            20933 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. CB01881 chromosome.
ACCESSION   NZ_CP026498
VERSION     NZ_CP026498.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CB01881
  ORGANISM  Streptomyces sp. CB01881
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     A 3-hydroxy-3-methylglutaryl-CoA synthase gene based probe for the
            discovery of the acyltransferase-less polyketide synthases
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2018) Xiangya International Academy of
            Translational Medicine, Tongzipo, Changsha, Hunan 410000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002953255.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 02:39:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,978
            CDSs (total)                      :: 7,904
            Genes (coding)                    :: 7,565
            CDSs (with protein)               :: 7,565
            Genes (RNA)                       :: 74
            rRNAs                             :: 5 (5S)
            complete rRNAs                    :: 5 (5S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 339
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 339
            Pseudo Genes (frameshifted)       :: 124 of 339
            Pseudo Genes (incomplete)         :: 251 of 339
            Pseudo Genes (internal stop)      :: 10 of 339
            Pseudo Genes (multiple problems)  :: 45 of 339
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:44:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10979354
            Orig. end                         :: 11000287
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026498.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20933
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="44"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20933
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20933
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10933](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10933
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     assembly_gap    81..90
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <91..1232
                     /locus_tag="C2142_RS37285"
                     /old_locus_tag="C2142_37330"
     CDS             <95..1232
                     /codon_start=3
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047646.1"
                     /locus_tag="C2142_RS37285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_37330"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_241003057.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.2e-06, bitscore:
                     28.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GLNPNGPAGPWAFPVPVFPEPSGDFAVGTRVVQWTDPRRPETFTA
                     DPNDRRTVVVQLWYPTQKSPAGAQRAQYLGRTEHEARTVSDALAREAGLPGFLVDGVPR
                     ARTRSVFDAPVDSTGGRFPVVLFSPGSGGVRTQNTAWAEELASHGYVVAALDHPYDSAA
                     VVLADGRTVNTETASSGDPDKDEELAAGWTAVRAADLGFVLTQLESLDRGEIADPLSGR
                     LDTARAAVAGHSMGGAAALQAARQDRRFDAVIDLDGYPHGPASPSLDQPTLALTQTITP
                     ATDPRYVPRLTEALKASTTTSYRLTIPGAAHLTFMDGPLYLPPVPSIVGSLGRTGSPRV
                     VAAASLAFLDAVLRAEPGDLAGVLPAYGNLSVYRPDNSR"
     gene            complement(1505..>2752)
                     /gene="kdpB"
                     /locus_tag="C2142_RS41270"
     CDS             complement(1505..>2752)
                     /EC_number="7.2.2.6"
                     /GO_component="GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA]"
                     /GO_function="GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="kdpB"
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962417.1"
                     /locus_tag="C2142_RS41270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="WP_241003058.1"
                     /transl_table=11
                     /translation="PPGLVQRNVVALSGRAVEAAGDVDVLLLDKTGTITHGNRRATALH
                     PLPGAAVEQLAEAARLASLADETPEGRSVIELTDRQYWVPPRAEGELGEQTTVPFTAQS
                     RMSGVDLAWPDGTTCLVRKGAANAVAHWVVRSGGRLPMEAKPLVDRISAAGGTPLLVAV
                     HDRHGARALGVIELKDVVKEGIADRFAELRRMGIRTVMVTGDNPLTARAIAAEAGVDDY
                     LAEATPEDKLAYLKREQAAGNMVAMTGDGTNDAPALAQADVGVAMNTGTPAAKEAGNMV
                     DLDSNPTKLIEIIRVGKQLLITRGALTTFSITNDVAKFFAIIPAMFVGSHPGLAHLNIM
                     GLHSPTSAIASAIIFNALIIVALIPLALRGVRYQPASATDLLRRNLRVYGLGGLILPFL
                     GIKAIDLLVQFVPGLG"
     assembly_gap    2753..2762
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<2763..3552)
                     /locus_tag="C2142_RS41275"
     CDS             complement(<2763..3552)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014136733.1"
                     /locus_tag="C2142_RS41275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="WP_241003344.1"
                     /transl_table=11
                     /translation="MAKNPVMLVVETGSALTTLTAVVHPGVFAWVISFWLWLTVLFANL
                     AEAVAESRGKAQADSLRQARTGTTARRLLHWRVGGHDHRHESIPAEHLLLHDIVLVPAG
                     EVIPRDGEVIEGVAAVDESAITGESAPVIRESGGDRTSVTGGTRVLSDRLVVRITARPG
                     QSFIDRMIALVEGANRQKTPNEIALNILLASLTIVFVLSVVSLQPMAIYAGSPQTTVVL
                     VALMVALIPTTIGALLSAIGIAGMDRLVQRNVVALSGRAVE"
     gene            4295..4849
                     /locus_tag="C2142_RS37295"
                     /old_locus_tag="C2142_37345"
     CDS             4295..4849
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571117.1"
                     /locus_tag="C2142_RS37295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_37345"
                     /product="universal stress protein"
                     /protein_id="WP_148647166.1"
                     /transl_table=11
                     /translation="MNGSHRNDERPRGRVVVGVSGSLGSLAALHRAVAEARRTGAEVIP
                     VLAWEPPGGELGYRRSPCPPLLAAVRDTAEQRLRDALDAAFAGADPGVPMHPLVVRGET
                     GPALVQTADRPGDLLVVGRSGGPLRRRLRRSVTDYCTRKAGCSVLAVARPELQQDLETL
                     HRRIHWHLPVGPAPELVRAKG"
     gene            4857..5264
                     /locus_tag="C2142_RS37300"
                     /old_locus_tag="C2142_37350"
     CDS             4857..5264
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS37300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_37350"
                     /product="hypothetical protein"
                     /protein_id="WP_148647167.1"
                     /transl_table=11
                     /translation="MRMYSARPGGHRYHPVLDRLPVAMSGTVALLAGGALALGLGRLGE
                     LHSGWFAYAAYAGLSALLGAFSRPSAAPVIGTAAWLCCNAFAEHRHAELGWAGAGAESG
                     HLVLFTAAALLLPLPAALPRRAVRVGRLPIV"
     CDS             complement(5457..>5725)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005475089.1"
                     /locus_tag="C2142_RS41280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_241003059.1"
                     /transl_table=11
                     /translation="NVKVVGSLDLVQTLLREKLFDRLDLWVHPIVLGVGKKVFDGGAVP
                     TNLTLLEPPVAGPNGTVYLRYGLADGTPRTGDMSAPDRGLGHDG"
     gene            complement(5457..>5727)
                     /locus_tag="C2142_RS41280"
     assembly_gap    5728..5737
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<5738..6102)
                     /locus_tag="C2142_RS41285"
                     /pseudo=""
     CDS             complement(<5738..6102)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005475089.1"
                     /locus_tag="C2142_RS41285"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="deaminase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGLIHIELFATLDLVGQAPGGPDEDPVGFPFGGWQAPLLDEVTGA
                     RVLAAYEGTDALLLGRRTYDLFASYWPHQKDGEIAELFNRVPKYVASRGTPDLPWAGST
                     QLGPDLAAAVREIRARE"
     gene            complement(6535..7242)
                     /gene="merB"
                     /locus_tag="C2142_RS37310"
                     /old_locus_tag="C2142_37360"
     CDS             complement(6535..7242)
                     /EC_number="4.99.1.2"
                     /GO_function="GO:0018836 - alkylmercury lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="merB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004946083.1"
                     /locus_tag="C2142_RS37310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_37360"
                     /product="organomercurial lyase"
                     /protein_id="WP_148647168.1"
                     /transl_table=11
                     /translation="MTGNISDTPKALHERERVRLAVYHGFARTGRAPSVPELAALTEVT
                     LGQVRQELRALHDRHDVVLDRQDNDRVVMAHPFASVPLGFSVMGAHTLWWGGCAWDSFA
                     MPHLLRDEPDVLVATRCPACDTPHAWVVGRDAPPWGGQVAHFLTPMRRAWDDVVHTCGN
                     QRLFCSTACVDTWLQRTGRERGYVMDLGTLWRLARDWYTGRLEPGYTRRDPASATAYIS
                     EVGLHGSFWGLPD"
     gene            7423..>7605
                     /locus_tag="C2142_RS41290"
                     /old_locus_tag="C2142_37365"
                     /pseudo=""
     CDS             7423..>7605
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014376.4"
                     /locus_tag="C2142_RS41290"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_37365"
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHAHDTYSFGVTDAGAQSFLRRGERHVSAAGLVMVFNPDEPHDGQ
                     SAVDHGYRYRMLHLGE"
     gene            complement(<7641..>7844)
                     /locus_tag="C2142_RS41295"
                     /pseudo=""
     CDS             complement(<7641..7844)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103693.1"
                     /locus_tag="C2142_RS41295"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRTRTAPAGSALGLRTVHRWTADADLLRLTITVAPEGDWTIPLPR
                     LGVRMGLPVAFGRARWFGGGPGE"
     gene            7896..8090
                     /locus_tag="C2142_RS37325"
                     /old_locus_tag="C2142_37375"
     CDS             7896..8090
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS37325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_37375"
                     /product="hypothetical protein"
                     /protein_id="WP_194235860.1"
                     /transl_table=11
                     /translation="MFIQTDDRFTLPLALLNYFQQQQFTGADFGALFAGVSISILPMVG
                     LYAWLGRRLTEGITRGAGK"
     gene            8600..8920
                     /locus_tag="C2142_RS37330"
                     /old_locus_tag="C2142_37380"
     CDS             8600..8920
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS37330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_37380"
                     /product="hypothetical protein"
                     /protein_id="WP_148647169.1"
                     /transl_table=11
                     /translation="MSTEPGLPTATQYRDLRGFVKNIERQAELERMNQGMEPTTYAVYS
                     AWMRMAVGYVALLGNDRTTPQATEAAARAWGTTLEMLEFWRNSPLLPESLRAPVAAASR
                     YR"
     gene            9215..9688
                     /locus_tag="C2142_RS37335"
                     /old_locus_tag="C2142_37385"
     CDS             9215..9688
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006348443.1"
                     /locus_tag="C2142_RS37335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_37385"
                     /product="hypothetical protein"
                     /protein_id="WP_241003060.1"
                     /transl_table=11
                     /translation="MSIWPSIVAVLGTLAGALTAGLLQHRSARTARTEERADSHRQDQL
                     GAVTEFAAALDAHRSAMFHRERLALAEAGTEHQLEAQTRSHDTRAAITAPHIRLQVLAP
                     ELAGPAQQAADATYALRKATDRTDLDARRHAAKEASAAFITAAATLLGPAAAN"
     assembly_gap    9849..9858
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            10001..10933
                     /locus_tag="C2142_RS37340"
                     /old_locus_tag="C2142_37390"
     CDS             10001..10933
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014133196.1"
                     /locus_tag="C2142_RS37340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_37390"
                     /product="terpene synthase family protein"
                     /protein_id="WP_241003061.1"
                     /sec_met_domain="T1TS (E-value: 1.7e-53, bitscore: 181.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWEWIDLRGLAATPKARARMLNTGADLSGAYVWPRAGLGMLSLGL
                     KWLALTFRIDDQLDEDDSDEQPGSRARCIEELCGILHDVPAPQSPVADALHELWKETRT
                     GRPASWQRVFVADFEAFLRSYALEAELKAAGRIPELPEYLGWRMYSVGMPWLWDLDELR
                     LPLHLPDSVRNCQTMSTLRRAGSLHIALVNDVFSVERESITGYPYNAVSLTMQAQGCSL
                     QEAVDQVADRVTEHAQAVSRMLERLPTELRHQQLPPDVRTAALDHSENIALNLRGQLAW
                     HASVRRYATTDITEQWAGNYPADLLRQAG"
     assembly_gap    11038..11047
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(11159..11440)
                     /locus_tag="C2142_RS37345"
                     /old_locus_tag="C2142_37395"
     CDS             complement(11159..11440)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS37345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_37395"
                     /product="hypothetical protein"
                     /protein_id="WP_148647171.1"
                     /transl_table=11
                     /translation="MSLIVLLEPELQRVDHLGSGGEEYVEGVRAVHAAEADPSVPGAPG
                     DHTLCGADTRRMQTVDYRPSAPGSPWYPPKWHGTGRVCRDCDRAVRSA"
     gene            complement(11640..11786)
                     /locus_tag="C2142_RS37350"
     CDS             complement(11640..11786)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS37350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_153882855.1"
                     /transl_table=11
                     /translation="MIDFGTLRRALDHHHDGEILGYARTVLDQPRPPSADRLKPPSAQP
                     SWR"
     gene            complement(11890..12216)
                     /locus_tag="C2142_RS37355"
                     /old_locus_tag="C2142_37400"
     CDS             complement(11890..12216)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139880.1"
                     /locus_tag="C2142_RS37355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_37400"
                     /product="MazG-like family protein"
                     /protein_id="WP_148647172.1"
                     /transl_table=11
                     /translation="MEEIWNVVNSLATKLDSHYDRSDEQRWAVQALKLQEEAGEVAEAV
                     IGALGANPRKGHSHDWDDVRKETCDVALSALVMLARMGGDPRRFFEEHLRSVATRDTKD
                     VTRT"
     gene            complement(12539..12988)
                     /locus_tag="C2142_RS37360"
                     /old_locus_tag="C2142_37405"
     CDS             complement(12539..12988)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS37360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_37405"
                     /product="hypothetical protein"
                     /protein_id="WP_148647173.1"
                     /transl_table=11
                     /translation="MSSVVEYELKLDWVRIDDVSEDSDDPVGEIYGKILLDDLTLWNPS
                     YENAFGNKRSDIAGMRAGEFFKLPADRSSRRHFDEDALNQSTAFRLQIRLMEQDDWNSD
                     DKIATVDEEIRPDLGELNGKTSLSAEKTASADGKITYRYTLTRIG"
     gene            complement(13597..>13872)
                     /locus_tag="C2142_RS41300"
                     /pseudo=""
     CDS             complement(13597..>13872)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139390.1"
                     /locus_tag="C2142_RS41300"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="purine permease"
                     /pseudo=""
                     /transl_table=11
                     /translation="TLGKADLSIGSNAIIVAVSLAFGIFPIAFPTFYQAFPEQIATVLN
                     SGISVGCLLAVTLNLLFNHLGRGREVPPAYVPEEQVEALGRVGDTA"
     assembly_gap    13873..13882
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<13883..15054)
                     /locus_tag="C2142_RS37365"
                     /old_locus_tag="C2142_37410"
     CDS             complement(<13883..15054)
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139390.1"
                     /locus_tag="C2142_RS37365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_37410"
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="WP_241003062.1"
                     /transl_table=11
                     /translation="MRRQTAPLEPGAPPHPVDEMLPPGRMATVALQHVASMYAGVAAPP
                     LIIGAAAGLTAARLTTLLAASLFIAGIATLLQTLGFWRIGSRLPFVNGVSFATVSPILA
                     VVESKKDAALPLIFGSTLVAGLFCFLLAPVFCRLVRFFPPVVSGTVITLIGISLLPVAG
                     NWAQGGNSRAPGYGSLANLGLAGLTLLAVLLFNRFLRGFLQRISILLGMLAGTLVAVPL
                     GKVDTAALGSLPVFELPHPFAFGAPQFEAAAIISMLVVMVVSMTESTADMIALGEVVER
                     PADDRTIAGGLRADGLATAFGGVFNGFICSAFAQNIGLVALTRIRSRFVVALAGVFLVV
                     MGLVPVVGGLVSLVPQPVLGGAGVVLFGSVAVAGIRTLGKADLSIGSNHRG"
     assembly_gap    15154..15163
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     misc_feature    complement(15221..15234)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.29"
                     /tool="antismash"
     misc_feature    complement(15761..15776)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     gene            16055..17191
                     /locus_tag="C2142_RS37370"
                     /old_locus_tag="C2142_37415"
     CDS             16055..17191
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="C2142_RS37370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_37415"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_148647175.1"
                     /transl_table=11
                     /translation="MLNYSLARPDDVDALLLLYREVYGSAYALPLGTDPEVMASEISSP
                     QTTWLVAREPGCGRLVGSIVGTLDPAARLGKLQGLVIHPDARGLGAGHLAVQQLSEAML
                     GGERPADSLYSTARTNSTAPQRICLQAGFRALGVLPNLRKAARHETMVLLARHREGVLE
                     QRLPVARVPQALGGLMRALDAVPGPHPRPELTDEPLPAPATGPGAELELVDAPQFVARH
                     FARHLPDPGQCFYPFHTPNVLLTPADGGYELYAQLSPSDGYCTLIGAEPGLSAVGDDLD
                     TITQKLAAHGASYLETLVPLDSYENLRLLLANGFLPVAAYPAMRREEHGFRDYVVMART
                     LQPLDFRGLSIDTAFQPFAEQYIELWKHQNLNTNGIFR"
     gene            17188..18366
                     /locus_tag="C2142_RS37375"
                     /old_locus_tag="C2142_37420"
     CDS             17188..18366
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014626766.1"
                     /locus_tag="C2142_RS37375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_37420"
                     /product="acyl-protein synthase"
                     /protein_id="WP_148647176.1"
                     /transl_table=11
                     /translation="MNQYLRPVAVPDADALAHVQQLCDIAEPYQAGPATDRLFTAAMNE
                     SNAWHAARSPFFDRLLKAGPGGGRPLDGIEELDRLPFVHANFFKAHEILSLPREDVLLH
                     LTSSGTTGQRSQMFFDEFTLRNGQRMVARVFDHYGWIDEREPVNYLLSNYQPRPGLNLG
                     TSFTDEYLCHFAPVRSVEYALKHTGSTHEFDPFGCVRTLIRYAEEGAPVRILGFPAFLS
                     FTLDRMRDLGIGPLELSPRSLVVFGGGWKGHADQQVAKPELYRRIHDQLGIPDERIRDG
                     FGAAEHSVLHMECPNHRLHVPVWARMLVRSVRDLTPLPYGEPGYAQFVSPYITSVPAQS
                     VLMGDLVTQHAPEECGCALPTPWFTVHGRAGLSRNRSCAVAAAELLKTEKAS"
     gene            18363..>19119
                     /locus_tag="C2142_RS37380"
                     /old_locus_tag="C2142_37425"
     CDS             18363..>19119
                     /GO_function="GO:0003995 - acyl-CoA dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008218 - bioluminescence [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017686.4"
                     /locus_tag="C2142_RS37380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_37425"
                     /product="acyl-CoA reductase"
                     /protein_id="WP_241003063.1"
                     /transl_table=11
                     /translation="MTSPTTPDATTDRHYWQGSWVDDTEAGRRLAGLDTCATEALAVPL
                     SPLTVLAACDRLAGLLADPASEQHRRLARLLDESGVGTAERERTLHDLTEALGREALET
                     KVTRELGGIDPGRLARFDFRREIFEGWLPVGLLVHIAPGNAPAAGALSVVEGLLAGNLN
                     IVKTSGGSRFTHALLADLAALDPTGAIAARTVVLGFPSSRTDWLARLCGAADAVAAWGG
                     EEAVNAIAALTPPGCRLVDWGPKLSFAYLT"
     assembly_gap    19120..19129
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
ORIGIN
        1 gcccgctggt ggctggcgtt gccgggatcg gtggcctgcg tcggcctgat cgccacgggc
       61 ccggtggccg cctgggcctt nnnnnnnnnn ccggcctcaa ccccaacggc ccggccggcc
      121 cctgggcctt tcccgtcccc gtgttccccg aaccgtcggg cgacttcgcg gtcggcaccc
      181 gcgtggtcca gtggaccgac ccacgccgcc ccgagacctt caccgcggat ccgaacgacc
      241 ggcgcacggt cgtggtccag ctctggtacc ccacgcagaa gagccccgca ggcgcgcagc
      301 gggcccagta cctcgggcgc acggagcacg aggcgcgcac cgtctccgac gccctcgccc
      361 gcgaggccgg cctgccgggt ttcctggtcg acggtgttcc gcgtgcccgc acccgttcgg
      421 tcttcgacgc cccggtggac agcacggggg gacggttccc cgtcgtactg ttctctcccg
      481 ggtcgggcgg agtgcgcacc cagaacaccg cctgggcaga ggaactggcc agccacggct
      541 atgtggtcgc cgccctcgac cacccgtacg actccgccgc cgtcgtcctc gccgacggcc
      601 gaacggtcaa caccgagacc gcctccagcg gcgacccgga caaggacgag gaactggcgg
      661 ccggctggac agcggttcga gccgccgacc tcggcttcgt cctcacccag ctggaaagcc
      721 tggaccgagg cgagatcgcc gacccgctga gcggacgcct ggacaccgcc cgggccgcgg
      781 tggccggcca ctccatgggt ggtgccgccg ccctgcaggc agcccggcag gatcgccggt
      841 tcgacgccgt catcgatctg gacggctacc cccacggccc cgcctcgccc tccctcgacc
      901 agccgacgct cgcgctcacc cagaccatca ccccggcaac cgacccgcgc tacgtacccc
      961 gtctcaccga ggcgctcaag gccagcacca cgacgagcta ccggctcacc atccccggcg
     1021 ccgcacatct cacgttcatg gacggccccc tgtatctgcc gcccgtgccc tcgatagtcg
     1081 gctccctggg ccgcaccggg agcccgcgcg tcgtcgcggc agccagcctc gccttcctgg
     1141 acgccgttct gcgagccgaa cccggcgacc tggccggcgt cctgccggcc tacggcaacc
     1201 tcagcgtcta ccgcccggac aacagccgct gaccggctgc ttccggggca ggtgcgtccg
     1261 gccgggccgc ctcggtcacc gcgcggtgga gcgccgcgag gctgcccggt gatccgctga
     1321 gtccgacgat cactctggtg gtgccggtca tggctgctcg cctcgcctcg gtcacgtgac
     1381 acccgatggt gcactgcttt catggaacgc cgtggcgggg cggccggtcc ggccgatgac
     1441 ggcaccatga cggccggagc ccggttcttg acggggcctt gacgagctgc cggttctccc
     1501 ggcctcagcc gaggccgggg acgaactgga cgagcaggtc gatggccttg atgccgagga
     1561 aggggaggat cagcccgccg aggccgtaga cgcgcaggtt gcggcggagc aggtcggtgg
     1621 cggaggcggg ctggtagcgg acgccgcgca gggcgagcgg gatcagggcg acgatgatca
     1681 gggcgttgaa gatgatcgcg gaggcgatgg ccgaggtcgg gctgtgcagg cccatgatgt
     1741 tgaggtgggc gaggccgggg tgggaaccga cgaacatcgc ggggatgatc gcgaagaact
     1801 tggcgacgtc gttggtgatc gagaaggtgg tcaacgctcc tcgggtgatg aggagttgct
     1861 tgccgacgcg gatgatctcg atcagtttgg tggggttgga gtcgaggtcg accatgttgc
     1921 cggcctcctt ggcggccggg gtgccggtgt tcatggcgac gccgacgtcg gcctgggcga
     1981 gggcgggggc gtcgttggtg ccgtcgccgg tcatcgcgac catgttcccg gcggcctgtt
     2041 cccgtttgag gtaggcgagt ttgtcctcgg gggtggcctc ggcgaggtag tcgtcgacgc
     2101 cggcctcggc ggcgatcgcg cgggcggtga gcgggttgtc gccggtgacc atgacggtgc
     2161 ggatgcccat ccggcgcagc tcggcgaagc ggtcggcgat gccctccttg accacgtcct
     2221 tgagctcgat cacgcccagc gcgcgggcgc cgtgccggtc gtggacggcg accagcagcg
     2281 gggtgccgcc ggcggcggag atccggtcga cgagcggctt ggcctccatc ggcaggcggc
     2341 cgccggagcg caccacccag tgggcgacgg cgttcgcggc gcccttgcgg accaggcagg
     2401 tggtgccgtc gggccaggcg aggtcgacgc cgctcatccg gctctgcgcg gtgaacggga
     2461 cggtggtctg ctcgcccagt tcgccctcgg cgcgcggtgg tacccagtac tggcggtcgg
     2521 tcagctcgat gacggagcgg ccctcggggg tctcgtcggc gagcgaggcg agccgggcgg
     2581 cctcggcgag ctgttcgacg gcggcgccgg ggagcgggtg gagggcggtg gcgcggcggt
     2641 tgccgtgggt gatggtgccg gtcttgtcga ggagcaggac gtcgacgtcg ccggccgcct
     2701 cgaccgcgcg gccggagagc gcgaccacgt tgcgctggac caggccaggc ggnnnnnnnn
     2761 nncctcgacc gcgcggccgg agagcgcgac cacgttgcgc tggaccaggc ggtccatgcc
     2821 ggcgatgccg atcgcggaga gcagcgcgcc gatcgtggtc gggatgaggg ccaccatgag
     2881 tgccaccagg acgacggtgg tctgcgggga gcccgcgtag atcgccatcg gctggagcga
     2941 gacgacggag aggacgaaga cgatggtgag cgaggcgagc aggatgttga gcgcgatctc
     3001 gttcggcgtc ttctgccggt tcgcgccctc gaccagggcg atcatccggt cgatgaagct
     3061 ctggcccggc cgcgcggtga tccggacgac cagccggtcg gagaggaccc gggtgccgcc
     3121 ggtgacgctg gtgcggtcgc cgccggactc gcggatgacg ggtgcggact cgccggtgat
     3181 cgccgactcg tccacggccg cgacgccctc gatcacctca ccgtcgcggg ggatcacctc
     3241 gccggcgggg acgagcacga tgtcgtgcag gaggaggtgc tcggcgggga tggactcgtg
     3301 gcggtggtcg tggccgccga cccgccagtg cagcaggcgg cgggcggtgg tgccggtccg
     3361 ggcctgccgc agcgagtcgg cctgggcctt gccgcggctc tcggcgacgg cctcggcgag
     3421 gttggcgaag agcacggtga gccagagcca gaagctgatc acccaggcga acacgcccgg
     3481 gtggacgacg gcggtgagcg tggtgagggc ggagccggtc tcgaccacca gcatgacggg
     3541 gttcttggcc atggtgcggg ggtggagctt gcgtaccgcg gcggggaggg cttcgcggag
     3601 ctggcgcgcg gtgatcagcc ggcggcgtcc ggaccgcggt gcgccggggc ggtggcccgg
     3661 gtgcggcggg gccggctcgg caccgccggc cttcgggcgg cggaaccggt cgggcctcgg
     3721 tgcgggctgt tcggtggtgg tggccggtga ggtgagggcc gggcggcgca tcggttctgg
     3781 gaccttccgg agccgccccg ggggagcggg gcggattgcg acggcgacgg gggacgtcgc
     3841 acagcgaagc accggatctc cgtacgccgt ccgcgtcttg acgcccgctt ggcacgacac
     3901 cggacgtcct tgacacgacc ctgacgcgac gacctgacga cctgtcggcc agcaggggct
     3961 ggcgcggtgg cggcgaccga gcggacgccg gctcgggcga ggtcgaggcg gcggaaggcg
     4021 ggaccgtccg gtacggcgga ccgaacgacc cgtgaccggt ccttgacgtc cttgacggaa
     4081 gcctggcggt gatcggctcg gtgctgacac gacctcggcg cgatccggac gcggccgccc
     4141 gcgacacggc gtcaagaccg cgttcggatc atggccggcc gcgtcagggt cccgtcaaga
     4201 acgcgcggac cggcagcctc ctgcggcttg gctggaggtc gtcgacaaca gccgacgaca
     4261 ggcgcgtgaa ccgcagcggc gtgaggatca ggacatgaac ggcagccacc ggaacgacga
     4321 gcggccccgg ggccgcgtgg tggtcggcgt gagcggctcc ctgggcagtc tggccgccct
     4381 gcaccgcgcg gtcgccgagg cccgccgcac cggcgccgag gtgattccgg tgctggcctg
     4441 ggagccgccc ggcggcgagc tcggctaccg ccgctccccg tgcccgccgc tgctcgcggc
     4501 cgtccgggac accgccgagc agcgcctgcg cgacgccctg gacgcggcct tcgccggcgc
     4561 cgacccgggc gtgccgatgc atccgctggt ggtccgcggc gagaccggtc ctgctctggt
     4621 gcagaccgcc gaccggcccg gggacctcct ggtggtgggg cgcagcggcg gcccgctgcg
     4681 ccgccgactg cggcgctccg tgaccgacta ctgcacgcgg aaggccggct gctccgtcct
     4741 cgccgtcgcg cggccggagc tccagcagga cctggagaca ctgcaccggc gcatccactg
     4801 gcacctcccg gtcgggccgg cgcccgagct ggtccgcgcg aagggatagg cccaccgtgc
     4861 ggatgtactc ggcccgcccc ggcggccacc gctaccaccc cgtgctggac cggctgcccg
     4921 tcgcgatgtc gggcacggtg gcgctcctcg ccggcggggc cctggcgctc ggcctgggcc
     4981 ggctcggtga gctgcactcc ggctggttcg cctatgcggc ctacgccggg ctgagcgcgc
     5041 tgctcggcgc cttctcccgg ccctcggcgg cacccgtgat cggcacggcc gcctggctgt
     5101 gctgcaacgc cttcgcggag caccgccacg ccgagctcgg ctgggccggc gccggcgcgg
     5161 agagcggcca cctcgtgctg ttcaccgcgg ccgccctgct gctcccgctc cccgcggccc
     5221 tgccgcgccg ggcagtccgg gtcggccgac tgccgatcgt gtgatcgtcg cgtgccggtg
     5281 ccgcctgcgc ccgaggcggc accggcacac gcgatgtggg ggtttgcgtg acggcggcga
     5341 ccctctggcg aggcacttcg tcagggcgtc ggcacctcga accgtcgacg tcgtggcgga
     5401 cgccgacccg gcggattcac cgccgatgag gcggcccgcc tggcgcgagg cggctttcag
     5461 ccgtcatgtc cgaggccgcg gtcgggtgcg ctcatgtcgc ccgtccgggg ggtgccgtcg
     5521 gcgagcccgt agcgcaggta cacggtgccg ttcgggccgg ccaccggtgg ttcgaggagt
     5581 gtgaggttcg tgggcaccgc gccgccgtcg aacaccttct tcccgacgcc gagcacgatc
     5641 gggtggaccc agaggtcgag acggtcgaag agcttctccc gcaggagggt ctgcaccagg
     5701 tccaggctcc cgacgacctt cacgttcnnn nnnnnnncgt tctcgtgcac ggatctcgcg
     5761 caccgcggcg gccaggtccg ggccgagctg cgtggacccg gcccacggga ggtcgggcgt
     5821 gccgcgggag gccacgtact tggggacgcg gttgaacagc tcggcgatct cgccgtcctt
     5881 ctggtgaggc cagtaggagg cgaagaggtc gtacgtccgc cggccgagca ggagggcgtc
     5941 cgtgccctcg tacgcggcga ggacccgcgc cccggtgacc tcgtccagca ggggcgcctg
     6001 ccagccgccg aacgggaacc ccaccgggtc ctcgtcgggt ccgccgggtg cctgcccgac
     6061 gaggtcgagg gtcgcgaaca gttcgatgtg gatgaggccc atgccttact cccgatgagg
     6121 tggcgaggcc cggcggcagg gcccggcagg tatgccgagc gccttggtcc aggcccgcac
     6181 gtccgattcc tcgaacagca cagtccgacc gatcctgaag tacgcagcac gcaatgcgaa
     6241 gcacgcagca cggtgccccg ctcacgccac cggaccggga cgccgcacca gcactcccgc
     6301 tcagggtaga tcacaggccg cgtcccgacc gggtggccgg cctgcgtcca gcgtcatctc
     6361 aggccaccgg cgcgatccac ggccgtggca ctggccgtgt ggtcaccgat gacctgggca
     6421 cacagggccg tgatgacccg atggggtgaa gggttgtgcc ccgagggcat cggtgggtca
     6481 ctcggcgcag ctgatcaatc acccggcact ctcgggcagc atgagggccg aacctcagtc
     6541 gggcagtccc cagaaggagc cgtgcaggcc gacctccgag atgtaggcgg tggcggaggc
     6601 ggggtcgcgg cgggtgtagc ccggttccag gcggccggtg taccagtcgc gggcgaggcg
     6661 ccacagggtg cccaggtcca tgacgtaacc gcgttcccgg cccgtccgct gaagccaggt
     6721 gtcgacgcag gcggtggagc agaacaggcg ctggttgccg caggtgtgca cgacgtcgtc
     6781 ccaggcccgg cgcatggggg tgaggaaatg ggccacctgg ccgccccacg ggggtgcgtc
     6841 ccggccgacg acccaggcgt gcggggtgtc gcaggccgga cagcgggtgg cgaccaggac
     6901 gtcgggctcg tcgcggagca ggtggggcat ggcgaacgag tcccaggcgc agccgcccca
     6961 ccacagggtg tgtgccccca tgacggagaa gccgagcggc acggacgcga aggggtgggc
     7021 catcacgacg cggtcgttgt cctgccggtc caggaccacg tcatgacggt catgaagggc
     7081 gcgcagttcc tgacgcacct gaccgagggt gacctcggtg agagcggcga gttccggcac
     7141 gctcggtgca cggccggtgc gcgcgaatcc gtggtagacg gccaggcgga ccctctcccg
     7201 ctcgtgaagg gccttcgggg tgtctgagat gttcccggtc attcctgtga ttcctccgct
     7261 ggtcgaggcg atgggtccag ggtgcgccgc ggcgaggtcc gggggcttga acgctcgtgc
     7321 ggcacacttg ggacataacg tctgccggag aacgggccgc ctactggcgg gttcccgggc
     7381 ttgcgctgga ggtcatcccg cttcgagcgg tacgcctatc cgatgcacgc ccacgacacg
     7441 tactccttcg gagtcaccga cgccggcgcc cagtccttcc tgcgcagggg agagcggcac
     7501 gtcagcgcgg ccggactggt catggtgttc aatcccgacg agccgcacga cggacagtcg
     7561 gccgtcgacc acgggtaccg ctaccggatg ctgcacctcg gcgaggacct tctccgggac
     7621 gtcctcgccg acgcggctcc ctcgcccggc ccgccgccga accaccgcgc tcgcccgaag
     7681 gccaccggca gacccatccg gacacccagc cgggggagtg ggatcgtcca gtcgccctcg
     7741 ggtgcgaccg tgatggtcag ccgcagcagg tccgcgtcgg cggtccagcg gtggacggtc
     7801 cgcagaccca gcgcactgcc ggcgggcgcc gtcctggtgc gcacctccca ggtgtcggcc
     7861 gtcagctcgg ggccgccgtc cgcctgctgg cgctgatgtt catccagacc gacgaccgct
     7921 tcaccctgcc gctcgccctg ttgaactact tccagcaaca gcagttcacg ggcgcggact
     7981 tcggcgccct gttcgccggg gtgtcgatct cgatcctgcc gatggtcggt ctctacgcgt
     8041 ggctcggccg ccgcctcacc gaggggatca ccaggggagc cggcaaatga gcgaggcgct
     8101 cagcccggcc gacccgccgc cccgtacccg acccgggcgc cgcgtgcacc gttgcagcgg
     8161 agccggccac cgccaggact ctcagccctg gctgcttcgg gggtgccttc gggcaccccc
     8221 gaaggcaccc ccgaagcccg gaccgcgcgc cttccttggc cttcaggcat gcgtctccgc
     8281 caaaaatccc gacgctatgc cctcgaccat gtcgtcctgc cgcactgcac acaacgccac
     8341 gcactgcggg agcgagactg ctggtgggtc agacagcggt gaggatggcg cccgccgcat
     8401 ggggctgggg tcaggccact gtctgtcggc cgtcggcgac gaccaaggca cggtgcactg
     8461 gttcgcgccg gaggcggccg ctgccgagca tctccgcgcc cgccggcttc gtctgtgtac
     8521 tcccggaagg cctgtgccgg atcaccttgc cgacggcgat attctccgag gctgctgacg
     8581 gaatcaacgg ggagcaccca tgagcacaga accaggcctg cccacggcca cgcagtaccg
     8641 cgacctgcgg ggattcgtga agaacatcga gcgtcaggcg gagctcgaac ggatgaacca
     8701 ggggatggag ccaacgacct acgccgtcta cagcgcctgg atgcggatgg ccgtcggcta
     8761 cgtcgccttg ctcggcaacg atcgaacgac gccccaggcc accgaggctg ccgcccgcgc
     8821 ctggggtacc acgctggaaa tgctcgaatt ctggcggaac agccccctac tgccagaatc
     8881 actgcgcgct cccgtcgcgg ctgcctccag gtaccgctga cccggccccc gggccggtgc
     8941 tcagccggcc aagtcgtcga gcggaagggt gaccgacggg gtggaacccg ggttgatccg
     9001 caggtccagg ccacgtgtcg gctgggtgag ctgtcgcccc gtcaaccggc tgaacccggc
     9061 ccagtggatg ggcaggtaac actccggcgt acacccctca gggacaggcc cggagcgccg
     9121 cgggcgtaac cccgccaccg actgcgccgc cgcgtgcttt gctgttcgcc gacctcacca
     9181 ccgaaaccga ctacccgaga ggggccgaca cctgatgtcc atatggcctt cgatcgttgc
     9241 cgtactcggt accctcgccg gtgccctgac cgctggactc ctccagcacc gttcggcacg
     9301 caccgcacgc accgaggagc gcgccgacag ccaccgccag gaccagctcg gcgccgtcac
     9361 cgagttcgcg gccgccctgg acgcgcaccg ctcggcgatg ttccatcggg agcgtctggc
     9421 cctggccgag gcaggcaccg agcaccagct ggaggcccag acgaggtccc acgacacccg
     9481 ggcggcaatc accgcgcccc acatccgcct tcaggtcctg gcccctgagc tggccggccc
     9541 cgcccagcag gccgcagatg ccacgtacgc gctgcgcaag gccaccgacc ggaccgactt
     9601 ggacgccagg cggcatgcgg ccaaggaggc atccgccgcc ttcatcaccg cggccgccac
     9661 gctgctgggc ccagcagccg ccaactgaga cctgctcacc tcgcccccca tgacgcccgg
     9721 cccggggacc atcggtacct cgtggcgccg cagctcctcg gggtgacgca ctgtgttcgc
     9781 gtacccaccg tatgctggtg atcttgatga ggccggggag ccggcaggcc cccaggcacg
     9841 acacgagann nnnnnnnntg atcttgatcg gggagccggc aggcccccag gcacgacacg
     9901 agagacacag gggcgggccg tgacagaaat ccgtatgcca gaattccatg ctccattccc
     9961 actggaatgc aaccctcacc tgcgggaagc ttccaagatc atgtgggagt ggatcgatct
    10021 ccgcgggctg gcggcgacac ccaaggcccg cgcccgcatg ctcaataccg gggccgacct
    10081 gtcgggcgcc tacgtatggc cgcgagccgg actcggcatg ctgtcactgg ggctgaagtg
    10141 gctggccctg acgttccgca tcgatgacca gctcgacgaa gacgactcgg acgagcagcc
    10201 cgggtcccgt gcgaggtgca tcgaggagct gtgcgggatc ctgcacgacg ttcccgcgcc
    10261 gcagtccccg gtcgccgacg ccctgcacga actgtggaag gagacgcgca cgggccggcc
    10321 ggcgagctgg cagcgcgtct tcgtcgccga cttcgaggcg ttcctgcgct cctacgccct
    10381 ggaggcagag ctcaaggccg ccggccgaat accggaactc cccgagtacc tcgggtggcg
    10441 gatgtactcg gtcggcatgc cgtggctgtg ggacctcgac gaactgcgcc tgccgctcca
    10501 cctccccgac agcgtgcgca actgccagac gatgagcact ctgcgccggg caggatcact
    10561 gcacatcgcc ctggtcaacg acgtgttctc cgtcgagagg gaaagcatca ccggttaccc
    10621 ctacaacgcc gtctccctca ccatgcaggc acagggctgc tccttgcagg aagcagtgga
    10681 ccaggtcgcc gaccgggtca ccgaacacgc ccaagcggtc agccgcatgc tcgaacgcct
    10741 tcccacagaa ctccggcacc agcagttgcc ccccgacgtc cgcacagccg ccctcgacca
    10801 ctccgagaac atcgccctga acctacgcgg acaacttgct tggcacgctt cagtgcgccg
    10861 ctacgccacc accgacatca ccgagcaatg ggcagggaac taccccgccg atctgctgcg
    10921 ccaggcaggc tgaccgggtc ggccccacgg catcgacggc gtcgtccgcc ttccccgcac
    10981 gggacataag aggccggtcc cgcccggctg ctggcgccgg ggagcggacg gcgccttnnn
    11041 nnnnnnnggc gtcgtccccc cgcacgggac ataagaggcc ggtcccgccc ggctgctggc
    11101 gccggggagc ggacggcgcc tttcgggcag cgttcgtacg gtgatcgagc agcgtgggtc
    11161 aggcagagcg gacggcacgg tcgcagtccc ggcagactct cccggtcccg tgccacttcg
    11221 gcgggtacca gggggaaccg ggggcggacg gccggtagtc cacggtctgc atccgccgag
    11281 tgtccgcacc gcacagagtg tggtcgccag gggcgccggg cacggacggg tcggcctcgg
    11341 ccgcgtgcac ggcacgcacg ccctcgacgt actcctcgcc gccgctgccg aggtggtcca
    11401 cccgttgaag ctcgggttcc agaagcacga tcagactcat caccccaccc tcggtgggaa
    11461 cgcaccgcgg cgcatccggg atcaggccgt cggggcgagc cgcgcgagga cccgtacgcg
    11521 caggacgacg gccgcgattg ccgctccagc tgttcgccgc gtagtggatc gtcgcgaccc
    11581 ggccgtgagc ccggtcgtgg gcgatcacgg ccacggcctg gcgaagtctc tccacagtgc
    11641 tacctccaag acggctgagc ggatgggggc ttcaggcggt cggcgctcgg tgggcgcggc
    11701 tggtccagga cggtgcgggc gtagccgagg atctccccgt cgtggtggtg gtcgagcgcc
    11761 cggcgcaggg tgccgaagtc gatcactgga agagctcctc ggtccgtggg caacacgggg
    11821 tcagccagcg gccggctgcc gcgggtcggt ccaccgctcg acctgcttcg tccttcggcg
    11881 gccggcaggt caggtacggg tgacgtcctt cgtgtcgcgg gtggcgaccg agcggaggtg
    11941 ctcctcgaag aacctgcggg ggtctccgcc catccgggcg agcatcacca gggcggacag
    12001 ggccacgtcg caggtctcct tgcgcacgtc gtcccagtcg tgggagtggc ctttccgggg
    12061 gttggcgccg agcgccccga tgacggcctc ggcgacctct ccggcctcct cctggagctt
    12121 gagggcctgt acggcccagc gctgctcgtc gctgcggtcg tagtgcgaat cgagctttgt
    12181 ggcaagggag ttgacgacat tccagatctc ttccatgggg gagatcctgc cgctgttcga
    12241 atgggtcgat caagccgggc ggttcccggc gagcctgggt cttttcgatt tcctgccggg
    12301 gcgggcaggt gcctctgcgc aggcgatggc cacctcttcg gcgatgccgg gccggcgtgg
    12361 gatcgtgtgt cctgcgggcg ttgggggtga tgacgggcgt gcgtggcgga ggcgaaggca
    12421 cagcgcgtgc cgtcaggagg gtgtccggct cttcggttct cacaacccga tgctggacac
    12481 cctccctaca ggtccggcgc agacaacggt gatcccagcc ggcctcggta ctactcgatc
    12541 agccgatccg cgtgagtgtg taccggtagg tgatcttgcc gtcggccgag gcggtcttct
    12601 ccgcgctcag gctcgtcttg ccgttgagct cgcccaggtc gggacggatc tcctcgtcga
    12661 ccgtggcgat cttgtcgtcc gagttccagt cgtcctgctc catcaaccgg atctgcaggc
    12721 ggaaggcggt ggactgattc agagcgtcct cgtcgaagtg cctccgcgag gaccggtccg
    12781 cgggaagttt gaagaactcg cccgcccgca tgcccgcaat gtccgagcgc ttgtttccga
    12841 aggcgttctc gtaggaaggg ttccacaggg tcaggtcgtc cagcaggatc ttgccgtaga
    12901 tctcgcccac ggggtcgtcg gagtcctcac tgacgtcgtc gatccgcacc cagtcgagct
    12961 tcagctcgta ttccactacg ctactcatgt tccctccagg aaacaggggt tcagagacag
    13021 agtggtccgc gcgtcgacgg cgcggacccg gacgggccac cccgctgcgg cctcggcctg
    13081 aggtgcccgc gctcacgcta gggtcgactg actcgctcgt ctgccgtgtc cgcgccgtga
    13141 tcgcccgttc agcggagtac gaccacctga gcgcagtgcg tcccggacgt tgcgagtggt
    13201 tcaaggagac agacctccgg ccgggggctc ccgaggtccg tccgtcagct gatcgagtcc
    13261 gccaacggta cccgcaacgg tcggttcggc ctcgaacagc acggtggtcc caccattgag
    13321 ggcgtcgccg cccggagcgg ccggtgacgg ccggccatga cgtgcgcgat ctggcacaac
    13381 cgcatcaccg gccgacccgt cacccgctca ctgaccgcct gccaccactg accgcctgcc
    13441 accactgacc gacttcggga ccacttgggc ccgccccacc ccgaccggcc tgtccaggag
    13501 acccgaatga tgcccccgct gcgccgccat ccgtgaggtc ggccgggtgg ccggcggacg
    13561 ggccgggcgg caggtgcgcc cggtccgtcg gaggggtcag gcggtgtccc ccacccgtcc
    13621 gagggcctcg acctgctcct ccggcacgta cgcgggcggg acctcgcgcc cccggcccag
    13681 gtggttgaag agcaggttca gggtgaccgc cagcaggcag cccaccgaga tgcccgagtt
    13741 cagcacggtc gcgatctgtt ccgggaaggc ctggtagaag gtggggaagg cgatcgggaa
    13801 gatgccgaac gcaaggctga ccgccacgat gatcgcgttc gacccgatgc tcaggtccgc
    13861 cttgcccagc gtnnnnnnnn nnccacgatg attcgacccg atgctcaggt ccgccttgcc
    13921 cagcgtgcgg atgcccgcca ccgccaccga cccgaagagc accacgcccg cgccgccgag
    13981 caccggctgc ggcaccagcg agaccagtcc gccgaccacc ggcaccaggc ccatcaccac
    14041 gaggaagacc ccggccagcg ccaccacgaa gcggctgcgg atccgcgtca gtgccaccag
    14101 cccgatgttc tgcgcgaacg ccgagcagat gaagccgttg aacacgccgc cgaacgccgt
    14161 cgcaagaccg tccgcccgca ggccgccggc gatcgtacgg tcgtccgccg ggcgctccac
    14221 cacctcgccg agcgcgatca tgtccgcggt ggactcggtc atcgagacca ccatcaccac
    14281 cagcatcgag atgatcgccg cggcctcgaa ctgcggcgcg ccgaaggcga acggatgcgg
    14341 cagctcgaag accggcaggc tgccgagcgc agcggtgtcc accttgccga gcgggaccgc
    14401 caccaaggtg cccgccagca tcccgagcag gatggagatc cgctgcagga agccgcgcag
    14461 aaagcggttg aagagcagga ccgcgagcag ggtcagcccc gccagtccca ggttggcgag
    14521 cgaaccgtag cccggcgcac gggagttgcc gccctgtgcc cagttcccgg ccaccggcag
    14581 cagtgagatg ccgatcagtg tgatcaccgt gccgctgacg accggcggga agaagcggac
    14641 gagccggcag aagaccggcg ccagcaggaa acagaacagg cccgccacca gggtcgaacc
    14701 gaagatcaac ggcagtgccg cgtccttctt cgactcgacc acggcgagga tcggcgagac
    14761 ggtggcgaag gagacaccgt tgacgaaggg cagccgcgag ccgattcgcc agaatcccag
    14821 ggtctgcagc agggtggcga tgccggcgat gaacaggctg gcggcgagca gggtggtgag
    14881 ccgggcggcg gtgagaccgg ctgcggcgcc gatgatcagc ggcggagcgg cgaccccggc
    14941 gtacatgctg gccacgtgct gaagcgcgac ggtcgccatc cggccgggcg gcagcatctc
    15001 gtcgacgggg tgtggtggtg ctccgggctc caggggtgct gtctggcgtc gcatgcgctg
    15061 ttccctccac gtccaaggtg gtttcgggcc cgggaacggc ggccggaacg ggacacggcg
    15121 acgttgggac gaccctggcg gacggcggtg ccgnnnnnnn nnngccgtcg ctgccgaacc
    15181 tgcggcgaac aggcccgacc catgagtgga tccacgatgc ggaacgttgg ttccgcgatt
    15241 cggtttccac aaaatgtaga aagctcggcc gggttggtca ataggtctcg ttcgattgcc
    15301 tctcggcact gccggatctg tgacttcctc caaccgcagc ccggcctggc agccgtacca
    15361 ggccgcgcaa cccggtgccg ggctgcgggg ccggccccga cgagaggggc gtgcgggcga
    15421 gctcggccat ctgcggagat ctcgaccatc cgagggggcg agaggcgagg gggcgggcgg
    15481 ggtcgagcgg ggcgtacacg attccgggcg ggggccgctt cgatgcgacg gcccggccgg
    15541 tgcccaccgc tcgtccgcga ggtccgacgg caacccgact ccaccaccgc tcgcaaaggg
    15601 ctcggcggcc acttcggccc caggatgcga cagctctccg atctggtccc ggaatcgccg
    15661 cctgcgggcg gtcggaccaa ttcgttcgtt gaaatccgta catatttgac gatccatcag
    15721 aggagttttg gcgaaccatc accgctgctt ctgaatggcc tgtgatcctc gtcgcaccgc
    15781 atcgggtgaa ccccttgtcc cgcctgccga tgcagcgtcg acctcccgcg aaggggtcat
    15841 cgtgacgccg aggtcgggtt agtgtgatgg gcagtcaact tacagtgact gcactccttc
    15901 gttcgtgccc gacgcggctc ttgcggacct gtccggtccg ccgcacggcg ctgcccgaaa
    15961 tccgggcctt cgccatcggg cgtgaattcg tttcttccat gtcgcgtccg cgccgatccg
    16021 tggacgtacc gccttcgtgg ggggaggcaa cccggtgctc aactattccc tggcgcgtcc
    16081 ggatgatgtc gacgcgctgc tcctgctgta ccgagaggtc tacggaagtg cgtacgcact
    16141 cccgctcggg accgatcccg aggtgatggc gagcgagatc agctctccgc agaccacctg
    16201 gctggtcgcc cgtgagccag gctgcggccg gctcgtcggc tcgatcgtcg gcaccctcga
    16261 ccctgccgcc cgcctcggca agctccaggg cctggtgatc cacccggacg cccggggcct
    16321 cggcgcgggc cacctggccg tccagcagct cagcgaggca atgctcggcg gcgagcggcc
    16381 ggccgattcg ctctactcga ccgcccgtac caactccacg gcgccgcaac ggatctgcct
    16441 gcaggccggg ttccgggcgc tcggcgtcct gccgaacctg cgcaaggccg cacggcacga
    16501 gaccatggtg ctgctggcac gccaccgcga gggcgtgctc gaacagcgcc ttccggtggc
    16561 gcgcgtcccg caggccctgg gcggtctgat gcgggccctg gacgccgtcc cgggcccgca
    16621 cccgaggccg gagctcaccg acgagccgct gccggccccg gcgacgggcc ccggcgcgga
    16681 gctcgaactc gtcgacgccc cgcagttcgt ggcccgccac ttcgcccggc acctgcccga
    16741 ccccgggcag tgcttctacc ccttccatac ccccaacgtc ctgctcaccc ccgctgacgg
    16801 cggctacgag ctgtacgcgc agctcagccc gtccgacggg tactgcacgc tgatcggcgc
    16861 cgaacccgga ctctccgcgg tcggcgacga tctggacacc atcacccaga agctcgccgc
    16921 ccacggcgcc agttacctcg aaaccctggt gccgctggac agttacgaga acctgcggct
    16981 gctgctcgcg aacggcttcc tgccggtggc cgcctacccg gcgatgcgcc gcgaggagca
    17041 cggcttccgc gactacgtgg tgatggcccg cactcttcag ccgctcgact tccgcggcct
    17101 gtccatcgac accgccttcc agccgttcgc cgagcagtac atcgaactgt ggaagcacca
    17161 gaacctcaac accaacggga tattccgatg aaccagtacc tgcgcccggt cgcggtaccc
    17221 gacgccgatg cgctggccca cgtacagcag ctctgcgaca tcgccgagcc gtaccaggcc
    17281 ggccccgcca cggaccgcct cttcaccgcg gccatgaatg agtccaacgc ctggcacgcg
    17341 gccaggtccc cgttcttcga ccggctgctc aaggccggcc cggggggcgg acgcccgctc
    17401 gacggcatcg aggaactcga ccggctcccc ttcgtccacg ccaacttctt caaggcccac
    17461 gagatcctct cgctgccccg cgaggacgtc ctgctgcacc tcacctcctc cggtaccacc
    17521 ggccagaggt cgcagatgtt cttcgacgag ttcaccctgc gcaacggcca gcgcatggtg
    17581 gcccgggtct tcgaccacta cggctggatc gacgagcggg agccggtcaa ctacctgctc
    17641 tccaactacc agccgcggcc cggcctcaac ctcggcacct cgttcaccga cgagtacctg
    17701 tgccacttcg ccccggtccg ctcggtcgag tacgccctca agcacaccgg cagcacccac
    17761 gagttcgacc ccttcggctg cgtccgcacc ctgatccgct acgccgagga gggcgccccg
    17821 gtgcggatcc tcgggttccc cgccttcctc tccttcaccc tggaccggat gcgcgacctg
    17881 ggcatcggcc cgctggaact ctccccgcgc tcgctggtcg tcttcggcgg cggctggaag
    17941 ggccacgcgg accagcaggt cgccaagccc gagctctacc gccggatcca cgatcagctg
    18001 ggcatcccgg acgagcggat ccgcgacggc ttcggcgccg ccgaacactc cgtcctgcac
    18061 atggagtgcc ccaaccatcg cctgcacgtg ccggtctggg cccggatgct ggtccgctcg
    18121 gtgcgcgacc tcacaccgct gccgtacggc gagccgggct acgcgcagtt cgtctcgccg
    18181 tacatcacct cggtgcccgc ccagtccgtc ctcatgggcg acctggtcac ccagcacgcg
    18241 cccgaggagt gtggctgcgc actgcccacc ccctggttca ccgtgcacgg ccgggccggc
    18301 ctcagccgca accgcagttg cgccgtcgcc gccgccgaac tcctcaagac cgagaaggcc
    18361 tcatgaccag ccccacgact cccgacgcga ccaccgaccg gcactactgg cagggcagct
    18421 gggtcgacga caccgaagcc gggcgacgcc tcgccgggct cgacacctgc gccaccgagg
    18481 ccctcgccgt cccgctcagc ccgctgaccg tgctcgccgc ctgcgaccgg ctcgccggcc
    18541 tcctggccga ccccgcgagc gagcagcacc gccggctcgc ccggctgctc gacgagtcgg
    18601 gcgtcggcac cgcggagcgc gagcgcaccc tgcacgacct caccgaggcg ctcggccgcg
    18661 aggccctgga gaccaaggtc acccgcgagc tcggcgggat cgaccccgga cggctggccc
    18721 gcttcgactt ccgccgggag atcttcgagg gctggctgcc ggtcggcctg ctggtgcaca
    18781 tcgccccggg caacgccccc gccgccgggg cgctcagcgt ggtcgagggc ctgctcgcgg
    18841 gcaacctcaa catcgtcaag accagtggcg ggagccgctt cacccacgcc ctgctcgccg
    18901 acctggccgc gctcgacccg accggcgcca tcgcggcgcg caccgtggtg ctgggcttcc
    18961 cctcgtcccg caccgactgg ctggcccggc tctgcggcgc cgccgacgcg gtcgccgcct
    19021 ggggcgggga ggaggcggtg aacgccatcg ccgccctcac cccgcccggc tgccggctgg
    19081 tcgactgggg ccccaagctc tccttcgcct acctcaccgn nnnnnnnnna cctggccgca
    19141 cccgaccggc gccatcgcgg cgcgcaccgt ggtgctgggc ttcccctcgt cccgcaccga
    19201 ctggctggcc cggctctgcg gcgccgccga cgcggtcgcc gcctggggcg gggaggaggc
    19261 ggtgaacgcc atcgccgccc tcaccccgcc cggctgccgg ctggtcgact ggggccccaa
    19321 gctctccttc gcctacctca ccgccgacgc ctggtccgat tccgaggtgc tcgcgggcat
    19381 cgcgcaggac atctgccgcc tggagcagca ggcctgcgcc agcccccagg tgatctacct
    19441 ggacaccgag gaccacgagc ggctcttcgc cttcgccgag cgcttcgccg ccgtcctcgc
    19501 cgcgcagccg cccactgcgg ccgagccgga gctgctggag agcgccgaga tcaccaacac
    19561 cgtgttggtg gcccgactgg aggaacacct gggcctcacc aaggtgcacg ccgaccccgc
    19621 cgcccgctgg cacgtcctgg ccgacacccg cgtcgccctg cgggcctccc cgctgcaccg
    19681 gaccgtctgg gtcaagccac tgccgcgcaa gcggatcggc gaggtgctgc gcccgatgcg
    19741 ccgctacctg cagaccgccg gtatcggcgc ctcccgccgc gacaccgccg agctggccgg
    19801 tgccgtcctg gccgccgggg tccagcgggt caccgtcccc gggcggatgc tggacagcta
    19861 cgacggcgag ccgcacgacg gtgtgtacgc gctgcagcgc tacagccgcc gggtggacgt
    19921 ccagctggac gcccgcttcg cctccgatgc ctgcctcgac gacctggtcg gcgcccgcga
    19981 gctgccgccc ccgccggtgc cggtgaccgc gaagaccgag ttcgagcagc tgcagggcga
    20041 cctcggccgg gccgaggtgt tcttccgcag cgggggcagc tccggcgcgc ccaagctgtc
    20101 ggccttcagc tgggacgact accacgagca catgcggcac ggggccgagg gtgtgctggc
    20161 ggcgggcttc gacccgcgca ccgaccgggc gatgaacctc ttcttcggag gccagctcta
    20221 cggcggcttc ctgagcttct actcggtcct ggagaacctg cgcgcggtgc agttcccgat
    20281 ggccgcccag gacgaccacg cggccgtcgc ccgctcgatc gtcgagcacc gggtggacac
    20341 cctcttcggc atgccgaact atctgctgcg ggtcttcacc gagggcgcgg acgtgctccg
    20401 cgggtaccgc ggggtgcgca agctcttcta cggcggagag cacttccccg agcgccggcg
    20461 cacgtggctg cgggaggagt tcggcgtcga gctgatccgc tcggccgcgt acggaagtgt
    20521 cgacgcgggc ccgctgggct accagtgccc ggacgccggg ggccgggtgc accacctgtt
    20581 cagcggactc cagacgctgg agatcctcga cctggaggag gaccgcccgg ccgatccggg
    20641 ccaggccgga aggctggtct tcaccgcgca cagccggcgc ggccagcgcc tggaccgcta
    20701 cgagatcggt gacctcggcc gctgggtgga cggcgcctgc ccctgcgggc ggcgcacccc
    20761 gcggttcgaa ctcctcggcc gcttcggcga catcttccgc agcggcagcc acttcctcaa
    20821 ctaccgtcgc ttcgtgctgg cggccgagga gcggctggac caccacgggg ccctccagct
    20881 gctcctcgac gaggacgagc acagcgcccg ggagacgctg accgtccgtc tgg
//
