LOCUS       NZ_CP026498            52345 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. CB01881 chromosome.
ACCESSION   NZ_CP026498
VERSION     NZ_CP026498.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CB01881
  ORGANISM  Streptomyces sp. CB01881
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     A 3-hydroxy-3-methylglutaryl-CoA synthase gene based probe for the
            discovery of the acyltransferase-less polyketide synthases
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2018) Xiangya International Academy of
            Translational Medicine, Tongzipo, Changsha, Hunan 410000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002953255.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 02:39:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,978
            CDSs (total)                      :: 7,904
            Genes (coding)                    :: 7,565
            CDSs (with protein)               :: 7,565
            Genes (RNA)                       :: 74
            rRNAs                             :: 5 (5S)
            complete rRNAs                    :: 5 (5S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 339
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 339
            Pseudo Genes (frameshifted)       :: 124 of 339
            Pseudo Genes (incomplete)         :: 251 of 339
            Pseudo Genes (internal stop)      :: 10 of 339
            Pseudo Genes (multiple problems)  :: 45 of 339
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:44:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10199792
            Orig. end                         :: 10252137
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026498.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..52345
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /candidate_cluster_numbers="4"
                     /candidate_cluster_numbers="5"
                     /candidate_cluster_numbers="6"
                     /contig_edge="False"
                     /product="NRPS"
                     /product="NRPS-like"
                     /product="terpene"
                     /product="butyrolactone"
                     /product="phosphonate"
                     /region_number="40"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /rules="AfsA"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..52345
                     /SMILES="NC(CC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /detection_rules="AfsA"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="NRPS-like"
                     /product="terpene"
                     /product="butyrolactone"
                     /product="phosphonate"
                     /protoclusters="1"
                     /protoclusters="2"
                     /protoclusters="3"
                     /protoclusters="4"
                     /protoclusters="5"
                     /tool="antismash"
     cand_cluster    1..>41647
                     /SMILES="NC(CC(=O)O)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>41647
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:>21647](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>21647
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(151..801)
                     /locus_tag="C2142_RS33890"
                     /old_locus_tag="C2142_33965"
     CDS             complement(151..801)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127453.1"
                     /locus_tag="C2142_RS33890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_33965"
                     /product="C39 family peptidase"
                     /protein_id="WP_241002933.1"
                     /transl_table=11
                     /translation="MEQGSGGDPAVVHEVPYYAQWESAGLVREIVAGAVSAADDPRWGE
                     SGAATPEEYEYWSWRLCGVACLRMALDHWWGVAPTAVQLAEECLAAGAYERDGERLRGL
                     IHTPFAAYVHQRWGLTAQARELTPAEVAAEVAEGRLVMLSVHPAIRHPDGPDPQRRGGH
                     LVLAVGTTATALVIHNPSGFAGESQAYAHVPWQRFERFYAGRGIVLGPPGVDG"
     gene            1072..2355
                     /locus_tag="C2142_RS33895"
                     /old_locus_tag="C2142_33975"
     CDS             1072..2355
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025791.4"
                     /locus_tag="C2142_RS33895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_33975"
                     /product="SUKH-4 family immunity protein"
                     /protein_id="WP_148646619.1"
                     /transl_table=11
                     /translation="MGIEQDWDGRLQLEPQQLPERLSHLPSREFLMQEGLPEAAAFLDF
                     SALDFSPLEPFAKDGGTGQHLFVLGETAYAAPRSHEGDAVVLDGVTGQVFLIGRRRGEL
                     RRDLLASGLSALVELMREVDVAALAAEEPEALGGERGPAIVAEVVRVVRERLRAMDPEL
                     FAHHRAAPPHWETALLVRSLAWGALPGGPARLAYEFGPELAEDLAAVTGNGQVRRFRPE
                     ELPGGLTHGPTRRLLTDVGLPLGGALLGVADDGPLVTMVEAYPEYFAPEYFAPGTGTGD
                     EHTPGGDPENDPDSDGDSDSDEWERDHQRHHIALAAWPHDLEIALDGATGRLELPAWND
                     PGIPEAYLNQDVSALLYTLWTCGRMRAEWRRWEHGAAGEAWALFDPQALLSGVVEGVLA
                     ALDPGAFATPDHSWQLLADDHSMGGLLH"
     cand_cluster    1724..>43082
                     /SMILES="NC(CC(=O)O)C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1724..>43082
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[21723:>23082](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      21724..>23082
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     gene            complement(2376..2918)
                     /locus_tag="C2142_RS33900"
                     /old_locus_tag="C2142_33980"
     CDS             complement(2376..2918)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004924945.1"
                     /locus_tag="C2142_RS33900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_33980"
                     /product="DUF4188 domain-containing protein"
                     /protein_id="WP_148646620.1"
                     /transl_table=11
                     /translation="MFAKPTPGYTTAAATGDTVVLLIGMRINRFWAVHHWGPVMMAMFR
                     MLSELAKAPERGLRGRVMLTASPRTYYIVQYWESKEKLYAYAAAPDAFHHKAWGMVNRK
                     VRGGKARQHVGLWHETYVVPEGSYESIYFDMPPFGLVAATGSLPLDRRGRRAADRFAFR
                     SKGEGVPEAAAAEEKAR"
     gene            complement(3016..3618)
                     /locus_tag="C2142_RS33905"
                     /old_locus_tag="C2142_33985"
     CDS             complement(3016..3618)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460689.1"
                     /locus_tag="C2142_RS33905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_33985"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_148646621.1"
                     /transl_table=11
                     /translation="MTERPARRGSYHHGALPEALVAAAFEVLDEQGLGAVSMREVARRA
                     GVSAGAPFRHFADRQALLTELADQVLADFERWQRAEIEGSEGSALRAIGLGFVRYAIRH
                     PHRFELVRARVFTPSRQPELQRRLSGIDEAFTGFIVADQEAGRLRPGDPALVGLAGQAL
                     VYGLSQMIIDGCLPPERAEELAAQVLDTFGQGVANPR"
     gene            complement(3680..5923)
                     /locus_tag="C2142_RS33910"
                     /old_locus_tag="C2142_33990"
     CDS             complement(3680..5923)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS33910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_33990"
                     /product="PE-PGRS family protein"
                     /protein_id="WP_153882842.1"
                     /transl_table=11
                     /translation="MTGGRSELDDVLDRAGLERVGSRGVPGARPVAAAWRAVRAGADHP
                     AVVVPADHPDLAAELNRQWHRLAVEHGVFERGVFERGGPSDGVGESSGHGASSGDESGS
                     SGVGGPPDDGSSDDGSSGVGGPFDGEGPSGEAGAFLIDVPDIPGAGCRCHRGWSRVRLS
                     DRWDLAGALGRQSGGPEFVTTSLDGERVLGCATEAGAVRLVVVRALSAWLEASARARAA
                     ADGGGDRSGDAGGDRSGDAGRRAVWEPVLARTTTSPQLRDKWRDGLAGNRAAPADVLIR
                     LLHGAPDERVPFGLHYRQLPDDVVDAWIAHPRPRVRRLLAERTSLTPAQRERLFREADA
                     RLRWILLVGLVDAGLELTDATYDLLAADASDQIRSELALHRDLPTRHLIAFAADQDASV
                     RRRVTPRAWPHLDDATRAALLADPDAPVRATARLRHHEAVPLAAADFDALPDSSDRGRA
                     AERCALTRELAEALAHGPDVGLRRAVARNAGLDADLVAVLGQDPDDSVRWRVSLRPELP
                     EEQRAGIRFDKDPAVRIPVLDWVREQQDDPAAMRRLAASRHFLVRRSVACAKNLPQDVA
                     DLLARDEDHAVRLLLAESCAQAPAELLSEMWRTWDGYSAARMPEHPNFPREHTLRHADH
                     PHPRMRELALDDPDSTEELVERLSRDPAYGVRWRALRDPRLSVASVIRLLDDPHDGIRS
                     TAAGDSRLPAHVLAGLLDDPATADSAAGNRALPAEVMRHLLELRPPAPAAVSA"
     misc_feature    5921..5936
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.02"
                     /tool="antismash"
     gene            complement(6002..6988)
                     /locus_tag="C2142_RS33915"
                     /old_locus_tag="C2142_33995"
     CDS             complement(6002..6988)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061481.1"
                     /locus_tag="C2142_RS33915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_33995"
                     /product="aldo/keto reductase"
                     /protein_id="WP_148646623.1"
                     /transl_table=11
                     /translation="MEFTHLGRTGLTVSRLCLGTMNFGPHTEESDAHLIMDTAHERGIN
                     FFDTANAYGRDNEGNLKGRTEEIIGRWFARGGGRRERTVLATKAYAPMGDWPNEGRLSA
                     LAIRRAVEDSLRRLNTDHIDLYQMHHIDRDTPWEEIWQAMEVLVTQGKIIYVGSSNFAG
                     WHLAQAQEAARARHFLGLVSEQSLYNLLDRTIELEVVPALQHYGLGLLPWSPLRSGLLG
                     GVLRKEREGTAVRGAMGHASEILAANRDRLQAYEDLAAELGTDPADLALAWLLSRPAVT
                     APIIGPRTPAHLEAAVGALDLKLAQKTLDRLDELFPGHKPAPEDYAW"
     gene            complement(7143..7928)
                     /locus_tag="C2142_RS33920"
                     /old_locus_tag="C2142_34000"
     CDS             complement(7143..7928)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014134519.1"
                     /locus_tag="C2142_RS33920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34000"
                     /product="ABC transporter permease"
                     /protein_id="WP_241002934.1"
                     /transl_table=11
                     /translation="MPGRLVSDTWSSMLRILLNYRHSPGLLAASLGVPVIMVVVFGYVF
                     GSAMQVPGGGNYREFLMPGLFAMVAVNGVMPTMVGAARDVGRGVTDRLRSMPVSRTGLL
                     LGQTLADFLVSIVVLALLAVVGLAAGWRIRGGTADAAEAFGLLLLLRFVMTWVGTFLGL
                     AVGKEEAAGQLAVAVFPLAMVTNAYVPTGGMPGWLRVVADWNPVSAAVQACRELFGNPS
                     APGGAWPMQHAVPATLLWCAALLAVCGPLAVRKFATHGR"
     gene            complement(7982..8935)
                     /locus_tag="C2142_RS33925"
                     /old_locus_tag="C2142_34005"
     CDS             complement(7982..8935)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014134520.1"
                     /locus_tag="C2142_RS33925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34005"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_206671083.1"
                     /transl_table=11
                     /translation="MTGVAKRFGARSGATEALRGLDLTVPAGTVCGLLGPNGAGKTTAV
                     RVLATLVAPDRGTARVAGYDVVREAEAVRRSVGLAGQHAAVDEGITGRENLDLLGRLHH
                     LGARAARARAGELLERFGLAEAGGRLVRTYSGGMRRRLDLVASLVTSPPVLFLDEPTTG
                     LDPRSRQEIWSTVKELAEGGTTVLLTTQYLEEADRLADDIVVIDHGAAIATGPPWRLKA
                     AIGTRIEVTLAEVGQLGRAAVVLAALAESGDVVVDHDQRTVAVVTRPGVEVLLPRLVRE
                     LDAAGVVAQDVGLRPPSLDDVFLALTADSNSLGRAA"
     gene            9069..9812
                     /locus_tag="C2142_RS33930"
                     /old_locus_tag="C2142_34010"
     CDS             9069..9812
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019066231.1"
                     /locus_tag="C2142_RS33930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34010"
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="WP_241002935.1"
                     /transl_table=11
                     /translation="MPSSKPPADSPPAPPEPPEAPELIWLRPERTGRGPKPAHSRASIA
                     AAAIAIADAEGLDAVSMRRVAAALGAGTMSLYNYVPKKEHLLDLMLDAVADEYDYDDLA
                     PAGDCRADLLRLGHAQLALMRRHPWLPALLIARPGIGPNALRYTDHFLAVTEPSGLDGG
                     TRMEAMALFNGFVCQYAQYERTGAAGAKWQAELVGYLTRAAMSGEYPHLSAAFATAGPP
                     ADPDTAFDRSLHRVITAALTPVERG"
     gene            complement(9963..11423)
                     /locus_tag="C2142_RS33935"
                     /old_locus_tag="C2142_34015"
     CDS             complement(9963..11423)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="C2142_RS33935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34015"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_148646626.1"
                     /sec_met_domain="Pkinase (E-value: 5.8e-52, bitscore:
                     175.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGVNGALIGGRYQLQELIGQGGMGRVWRGLDTTLGRDVAVKEVL
                     LPQGVTEAEREQLVQRVLREARAAARLNHPGIITVHDVVEHEGAPVIVMEYVSGLSLAA
                     AIARDGALPAARVAEIGVAMVKALQQAHAAGIVHRDLKPDNVLLMGDRVILTDFGIAHM
                     ADATTALTRTGAVIGTPAYMAPEQLEGKPAAPANDLWSLGATLYAAVEGEMPFSGDTFG
                     ALCVAVVTKEPRRPVRAGALTPLLGALLAKDPAQRPSAEQTLAALEAVARAAVPVAPVG
                     PVATPTAPDVAGGGGWYGPPQPLTAPQPPPGAPQPGSAGAWLPPQAGQAAPTPPLLPPA
                     SSGTSASSGATAPSAPAAPSAAGAILVRFIGCMGLIWAIGSALPWNYLGTIPDRFVPHA
                     LLVTAVLSLVHAVPRPRWHPAVVWAVTVTADLGLFFVTKAVVAQWLGTGQLGFGEEPGQ
                     MALNMLLLGTGVWLLWLLVPGSRRPARP"
     gene            11654..12814
                     /locus_tag="C2142_RS33940"
                     /old_locus_tag="C2142_34020"
     CDS             11654..12814
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010644348.1"
                     /locus_tag="C2142_RS33940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34020"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_148646627.1"
                     /transl_table=11
                     /translation="MQQYQGHADEGFGAVADAFARNYADFPELGSAVTVFAGGRKVVEL
                     WGGVADERTGRPWEAGTVVPVFSCAKGLVAVCAHLLAQQGRLDLDAPVSRYWPEFAQHG
                     KEDVTCRMVLGHRAGIPALDAVLGFEEIAAWAPVVRAIEEQKPLWEPGTTYEYHGHVLG
                     FLVGEVIRRITGLTPGAFFRQEIGDPLGLDAWIGLPAAELHRLARLVEAEGRRPMPGPE
                     HLLTRIVTMNGALVFPGLDVPHGWNDPELHAIELPGAGAVASASGLAGLYAAAVTGIEG
                     GRDGGRERLLSPAIVTDVVREVSSGAGFLGFDMGARWGSGVLLESPAFRPMLGARSFGN
                     DGAGGQFAFGDDEFGIGFAYVANRMIGHGDARANHLVDAVRTCLGA"
     gene            complement(12902..13279)
                     /locus_tag="C2142_RS33945"
                     /old_locus_tag="C2142_34025"
     CDS             complement(12902..13279)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS33945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_34025"
                     /product="hypothetical protein"
                     /protein_id="WP_148646628.1"
                     /transl_table=11
                     /translation="MLVRAGSWTVGPERWKGPREAIVVERELCDTSRHLIVRTEPEDGA
                     VATVTWGAVLRFALWGFGFMAVLSGILFAFVGVVQGSAVPGITAGLLVACAVYFAVAGH
                     RLGCAAKKALVTVFGWWEYVF"
     gene            13372..13824
                     /locus_tag="C2142_RS33950"
                     /old_locus_tag="C2142_34030"
     CDS             13372..13824
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298: putative carboxymuconolactone decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384460.1"
                     /locus_tag="C2142_RS33950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34030"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_174315799.1"
                     /transl_table=11
                     /translation="MTTVQIPQRMNFSVTAPKVFRAVLALDAAAREGLDPVLVELVQIR
                     ASQINRCAYCLDYHTTDARKAGETEDRVHQLSAWEESSLYTAKERAALALTEAVTVLPQ
                     GVPDAVYAQAAEHFEEKELAQLIALIFTVNTWNRMNVSTRKTPGTA"
     misc_feature    13977..13992
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.44"
                     /tool="antismash"
     gene            14178..15263
                     /locus_tag="C2142_RS33955"
                     /old_locus_tag="C2142_34035"
     CDS             14178..15263
                     /NRPS_PKS="Domain: TIGR01720 (202-329). E-value: 1.1e-31.
                     Score: 101.8. Matches aSDomain:
                     nrpspksdomains_C2142_RS33955_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="C2142_RS33955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34035"
                     /product="DUF6271 family protein"
                     /protein_id="WP_208693245.1"
                     /sec_met_domain="Condensation (E-value: 5.8e-24, bitscore:
                     83.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRICLALPTNRACAATISAVGEEAAYAAEQFGVEVHLALSGSPE
                     QPIVLPAKTTSFRDWARHLHDHAQTEEIGAQTEHWLETLRAGEESGVLLDLLPDDDETL
                     ESVNTRASACSVTVALEAEQTKLLLQEAPSAYQARIEELLLTATGLALTDALGERQVLV
                     ELEGHGREDLGPQLDLSRTVGWFTSAYPVLLDIAPGASVAGALRQVREQRRRVPGDGLG
                     YGLLRHLRTGDPLAAELAELPAAAVCFNYLGQLDQSFQPGGLWEPASENPGPGLDARAT
                     RSHLIEVNALVLGEELRFTWTYSDRLYREETIAGLAEHCLGTLRALIAGRPAAGDGNRG
                     ADSGSVPGPRELSELLGRFDA"
     CDS_motif       14709..14759
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33955_0001"
                     /evalue="1.20E-09"
                     /label="NRPS-E5"
                     /locus_tag="C2142_RS33955"
                     /protein_end="194"
                     /protein_start="177"
                     /score="30.0"
                     /tool="antismash"
                     /translation="DLSRTVGWFTSAYPVLL"
     aSDomain        14784..15164
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS33955_TIGR01720.1"
                     /evalue="1.10E-31"
                     /label="C2142_RS33955_TIGR01720.1"
                     /locus_tag="C2142_RS33955"
                     /protein_end="329"
                     /protein_start="202"
                     /score="101.8"
                     /tool="antismash"
                     /translation="AGALRQVREQRRRVPGDGLGYGLLRHLRTGDPLAAELAELPAAAV
                     CFNYLGQLDQSFQPGGLWEPASENPGPGLDARATRSHLIEVNALVLGEELRFTWTYSDR
                     LYREETIAGLAEHCLGTLRALIA"
     CDS_motif       14802..14864
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33955_0002"
                     /evalue="9.50E-11"
                     /label="NRPS-E6"
                     /locus_tag="C2142_RS33955"
                     /protein_end="229"
                     /protein_start="208"
                     /score="33.8"
                     /tool="antismash"
                     /translation="VREQRRRVPGDGLGYGLLRHL"
     gene            15325..>16586
                     /locus_tag="C2142_RS33960"
                     /old_locus_tag="C2142_34040"
     CDS             15325..>16586
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (3-29). E-value: 4.5e-13.
                     Score: 40.2. Matches aSDomain:
                     nrpspksdomains_C2142_RS33960_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (8-308). E-value:
                     1.7e-118. Score: 387.0. Matches aSDomain:
                     nrpspksdomains_C2142_RS33960_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="C2142_RS33960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34040"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_241002936.1"
                     /sec_met_domain="Condensation (E-value: 7.8e-75, bitscore:
                     250.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDAMTIESVHPLAPMQEGMWFHALYTPEDDVYVEQVTCLIEGSL
                     DAAAFRRAWDEVVARHTALRTSFHAVDGKAPVQAVHRAVEVPWTREDWRDVPAEERQDR
                     LDAFLREDRARGFDPARPPLVRFALLRLDDAAHQFVWTHHHLLLDGWSVPLVLQEVAAC
                     YAAARDGRPAALPVPRPYQEYVGWLERQDEAAAEDFWRTGLRGFHEPTPLPLDRGPGEA
                     DTPPEHRVRRTGLPRSVTAELQTMARRYGITPNTVVQGAWALLLSRYSGGQDVLHGMTV
                     AGRPADLPGVEDMVGLFINTVPVRIQVQPHLPAGDWLRGLQAGLLDLRSHEHTPLARVQ
                     SWADVGSGVPLFESLVVFENYPVAPSEAQEAFAGLTISQNETEERTNFPVTLVAVPGSA
                     LGLQLIFDHHRLAPQDATTLL"
     aSDomain        15334..15411
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS33960_NRPS-COM_Nterm.1"
                     /evalue="4.50E-13"
                     /label="C2142_RS33960_NRPS-COM_Nterm.1"
                     /locus_tag="C2142_RS33960"
                     /protein_end="29"
                     /protein_start="3"
                     /score="40.2"
                     /tool="antismash"
                     /translation="AMTIESVHPLAPMQEGMWFHALYTPE"
     aSDomain        15349..16248
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS33960_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.70E-118"
                     /label="C2142_RS33960_Condensation_DCL.1"
                     /locus_tag="C2142_RS33960"
                     /protein_end="308"
                     /protein_start="8"
                     /score="387.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLLLDG"
                     /tool="antismash"
                     /translation="SVHPLAPMQEGMWFHALYTPEDDVYVEQVTCLIEGSLDAAAFRRA
                     WDEVVARHTALRTSFHAVDGKAPVQAVHRAVEVPWTREDWRDVPAEERQDRLDAFLRED
                     RARGFDPARPPLVRFALLRLDDAAHQFVWTHHHLLLDGWSVPLVLQEVAACYAAARDGR
                     PAALPVPRPYQEYVGWLERQDEAAAEDFWRTGLRGFHEPTPLPLDRGPGEADTPPEHRV
                     RRTGLPRSVTAELQTMARRYGITPNTVVQGAWALLLSRYSGGQDVLHGMTVAGRPADLP
                     GVEDMVGLFINTVPVRIQV"
     CDS_motif       15358..15393
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33960_0001"
                     /evalue="4.60E-05"
                     /label="C1_dual_004-017"
                     /locus_tag="C2142_RS33960"
                     /protein_end="23"
                     /protein_start="11"
                     /score="16.1"
                     /tool="antismash"
                     /translation="PLAPMQEGMWFH"
     CDS_motif       15415..15531
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33960_0002"
                     /evalue="6.40E-20"
                     /label="C2_DCL_024-062"
                     /locus_tag="C2142_RS33960"
                     /protein_end="69"
                     /protein_start="30"
                     /score="63.5"
                     /tool="antismash"
                     /translation="DVYVEQVTCLIEGSLDAAAFRRAWDEVVARHTALRTSFH"
     CDS_motif       15751..15816
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33960_0003"
                     /evalue="1.20E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="C2142_RS33960"
                     /protein_end="164"
                     /protein_start="142"
                     /score="37.0"
                     /tool="antismash"
                     /translation="HHHLLLDGWSVPLVLQEVAACY"
     CDS_motif       15862..15900
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33960_0004"
                     /evalue="2.60E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="C2142_RS33960"
                     /protein_end="192"
                     /protein_start="179"
                     /score="10.5"
                     /tool="antismash"
                     /translation="PYQEYVGWLERQD"
     CDS_motif       16144..16239
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33960_0005"
                     /evalue="2.60E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="C2142_RS33960"
                     /protein_end="305"
                     /protein_start="273"
                     /score="61.6"
                     /tool="antismash"
                     /translation="DVLHGMTVAGRPADLPGVEDMVGLFINTVPVR"
     CDS_motif       16291..16410
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33960_0006"
                     /evalue="9.30E-21"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="C2142_RS33960"
                     /protein_end="362"
                     /protein_start="322"
                     /score="66.3"
                     /tool="antismash"
                     /translation="AGLLDLRSHEHTPLARVQSWADVGSGVPLFESLVVFENYP"
     assembly_gap    16587..18126
                     /estimated_length=1540
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <18127..20004
                     /locus_tag="C2142_RS33965"
                     /old_locus_tag="C2142_34045"
     CDS             <18127..20004
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: PCP (51-119). E-value: 3.2e-27. Score:
                     86.5. Matches aSDomain: nrpspksdomains_C2142_RS33965_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (141-442). E-value:
                     3.5e-93. Score: 303.8. Matches aSDomain:
                     nrpspksdomains_C2142_RS33965_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="C2142_RS33965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34045"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_241002937.1"
                     /sec_met_domain="PP-binding (E-value: 5.5e-16, bitscore:
                     57.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.7e-66, bitscore:
                     222.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="HLPDHMIPTTYTLLDTLPLTPNGKTDYRALPTPEPAAESLGTSYR
                     APRSAVEAVLAAVWQDVLGVDRIGVDDDFFALGGHSLLAARVHNRLRAVFGVEVPLRLL
                     FSEPTVARLAAAVEAVRRAQTGAAAEALPPLLPGDRAEPAPLSFAQRRLWFLEGWEPGT
                     SLYHITAAVRLRGPFDVAAFRTAWQRLIDRHDVMRAHVDDGDPGEPRQVVRSGCPAAVP
                     LVDLSAVPEGDRGSAVTRLVNEVTDRPFELTTGPLWRVALLRLGPAEHVLAIGLHHLIA
                     DGHSLEVLLAELGAQYEAAEAGRKLELPALPVQFADYARWQRGWLEGDRLSEELGYWKK
                     QLGGLPAITLPTDRAREAARGVGAAIESVQLSASADARLQAISREAGVTPFMALLAVFA
                     VALGQNRDLDEVVVGTPIVGRSRAELEGLIGFFANTLVLRLDLAGDPTFRELLGRAREV
                     CLDAYAHQDVPFERVVQELRPERSDSHLPLFQTWFVVQEAPAVAEAFAGLGVEPVRHGE
                     QQARYDLRLDVQRIGDTLRAVFEYKTDLFESASVARLARRFGHLLEVAAVEPDARLSAL
                     TRQVGEADDRARRERRGSVSLASLKRLKNVRREITQEAGGSKPAEGGIA"
     cand_cluster    18223..41951
                     /candidate_cluster_number="4"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="3"
                     /tool="antismash"
     protocluster    18223..41951
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[28222:31951](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      28223..31951
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="3"
     aSDomain        18283..18486
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS33965_PCP.1"
                     /evalue="3.20E-27"
                     /label="C2142_RS33965_PCP.1"
                     /locus_tag="C2142_RS33965"
                     /protein_end="119"
                     /protein_start="51"
                     /score="86.5"
                     /tool="antismash"
                     /translation="EAVLAAVWQDVLGVDRIGVDDDFFALGGHSLLAARVHNRLRAVFG
                     VEVPLRLLFSEPTVARLAAAVEA"
     CDS_motif       18286..18321
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33965_0001"
                     /evalue="5.70E+00"
                     /label="Cy4"
                     /locus_tag="C2142_RS33965"
                     /protein_end="64"
                     /protein_start="52"
                     /score="0.4"
                     /tool="antismash"
                     /translation="AVLAAVWQDVLG"
     aSDomain        18553..19455
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS33965_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.50E-93"
                     /label="C2142_RS33965_Condensation_LCL.1"
                     /locus_tag="C2142_RS33965"
                     /protein_end="442"
                     /protein_start="141"
                     /score="303.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLIADG"
                     /tool="antismash"
                     /translation="EPAPLSFAQRRLWFLEGWEPGTSLYHITAAVRLRGPFDVAAFRTA
                     WQRLIDRHDVMRAHVDDGDPGEPRQVVRSGCPAAVPLVDLSAVPEGDRGSAVTRLVNEV
                     TDRPFELTTGPLWRVALLRLGPAEHVLAIGLHHLIADGHSLEVLLAELGAQYEAAEAGR
                     KLELPALPVQFADYARWQRGWLEGDRLSEELGYWKKQLGGLPAITLPTDRAREAARGVG
                     AAIESVQLSASADARLQAISREAGVTPFMALLAVFAVALGQNRDLDEVVVGTPIVGRSR
                     AELEGLIGFFANTLVLRLDL"
     CDS_motif       18568..18600
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33965_0002"
                     /evalue="1.80E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="C2142_RS33965"
                     /protein_end="157"
                     /protein_start="146"
                     /score="10.7"
                     /tool="antismash"
                     /translation="SFAQRRLWFLE"
     CDS_motif       18622..18729
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33965_0003"
                     /evalue="4.50E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="C2142_RS33965"
                     /protein_end="200"
                     /protein_start="164"
                     /score="51.2"
                     /tool="antismash"
                     /translation="LYHITAAVRLRGPFDVAAFRTAWQRLIDRHDVMRAH"
     CDS_motif       18955..19020
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33965_0004"
                     /evalue="5.10E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="C2142_RS33965"
                     /protein_end="297"
                     /protein_start="275"
                     /score="22.3"
                     /tool="antismash"
                     /translation="LHHLIADGHSLEVLLAELGAQY"
     CDS_motif       19069..19107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33965_0005"
                     /evalue="1.70E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="C2142_RS33965"
                     /protein_end="326"
                     /protein_start="313"
                     /score="17.3"
                     /tool="antismash"
                     /translation="QFADYARWQRGWL"
     CDS_motif       19288..19338
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33965_0006"
                     /evalue="2.50E-03"
                     /label="Cy4"
                     /locus_tag="C2142_RS33965"
                     /protein_end="403"
                     /protein_start="386"
                     /score="11.0"
                     /tool="antismash"
                     /translation="GVTPFMALLAVFAVALG"
     CDS_motif       19357..19446
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33965_0007"
                     /evalue="2.50E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="C2142_RS33965"
                     /protein_end="439"
                     /protein_start="409"
                     /score="52.0"
                     /tool="antismash"
                     /translation="EVVVGTPIVGRSRAELEGLIGFFANTLVLR"
     CDS_motif       19495..19611
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS33965_0008"
                     /evalue="1.70E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="C2142_RS33965"
                     /protein_end="494"
                     /protein_start="455"
                     /score="71.9"
                     /tool="antismash"
                     /translation="REVCLDAYAHQDVPFERVVQELRPERSDSHLPLFQTWFV"
     gene            20001..>21647
                     /locus_tag="C2142_RS41800"
                     /old_locus_tag="C2142_34050"
                     /pseudo=""
     CDS             20001..>21647
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Interface (7-435). E-value: 5.8e-94.
                     Score: 307.3. Matches aSDomain:
                     nrpspksdomains_C2142_RS41800_Interface.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="C2142_RS41800"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34050"
                     /product="condensation domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 5.9e-36, bitscore:
                     122.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1e-17, bitscore:
                     62.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSAIEGYRLSTQQRHIWGLLAAGRPESYAAWCAVRVQEPCDPRQ
                     LRAALERLAARHEILRTVFRRPAGVEVPLQVISDDRTEVGFETHDLRELPADEQRKRYA
                     ELREAWPARPVDLEHGPALSAALVLMTGKPGDTAQLLLRLPAVCADEASLRVLVGELAQ
                     DGEPDDEPDDGPLQYADFAQWQNDLLTAEEFGLEREYWLGQDPAGLVGPELPFSGHSAE
                     KALFRPAVLRRQLQAELRTGLRELAWQLGVEPSTVVLAVWRLLLERIATAADFAVGVRF
                     DNRGAEELRSAVGAFVKYLPSSTRSGSDESLAGFARRLQDELDRMGEVQEYFGWEQIES
                     RLPQTRSGALFTAAFDWSAVEPVPRARTFQLDEADAVTERFEVRVAARDDGGSLRLDLW
                     YDTGVLSPVDARLLSGQLLAVLRAAVADPGTSLRALAVVDAAPEDGRPADRVPATGGRG
                     TDAVHVQVAEQARRHPQREAVRVLDRTLSYAELDEGANRLAHHLRSLGADADRPIGLCL
                     DRSVDFVVGLLGIMKAGGAYLPLDPALPAARR"
     aSDomain        20022..21305
                     /aSDomain="Interface"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS41800_Interface.1"
                     /evalue="5.80E-94"
                     /label="C2142_RS41800_Interface.1"
                     /locus_tag="C2142_RS41800"
                     /protein_end="435"
                     /protein_start="7"
                     /score="307.3"
                     /tool="antismash"
                     /translation="YRLSTQQRHIWGLLAAGRPESYAAWCAVRVQEPCDPRQLRAALER
                     LAARHEILRTVFRRPAGVEVPLQVISDDRTEVGFETHDLRELPADEQRKRYAELREAWP
                     ARPVDLEHGPALSAALVLMTGKPGDTAQLLLRLPAVCADEASLRVLVGELAQDGEPDDE
                     PDDGPLQYADFAQWQNDLLTAEEFGLEREYWLGQDPAGLVGPELPFSGHSAEKALFRPA
                     VLRRQLQAELRTGLRELAWQLGVEPSTVVLAVWRLLLERIATAADFAVGVRFDNRGAEE
                     LRSAVGAFVKYLPSSTRSGSDESLAGFARRLQDELDRMGEVQEYFGWEQIESRLPQTRS
                     GALFTAAFDWSAVEPVPRARTFQLDEADAVTERFEVRVAARDDGGSLRLDLWYDTGVLS
                     PVDARLLSGQLLAVLRAAVADPGTSLRAL"
     CDS_motif       20100..20195
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS41800_0001"
                     /evalue="9.80E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="C2142_RS41800"
                     /protein_end="65"
                     /protein_start="33"
                     /score="30.9"
                     /tool="antismash"
                     /translation="AVRVQEPCDPRQLRAALERLAARHEILRTVFR"
     CDS_motif       20529..20567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS41800_0002"
                     /evalue="2.50E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="C2142_RS41800"
                     /protein_end="189"
                     /protein_start="176"
                     /score="16.8"
                     /tool="antismash"
                     /translation="QYADFAQWQNDLL"
     CDS_motif       21261..21290
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS41800_0003"
                     /evalue="8.50E+00"
                     /label="Cy2"
                     /locus_tag="C2142_RS41800"
                     /protein_end="430"
                     /protein_start="420"
                     /score="-0.4"
                     /tool="antismash"
                     /translation="LRAAVADPGT"
     CDS_motif       21582..21623
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS41800_0004"
                     /evalue="5.00E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="C2142_RS41800"
                     /protein_end="541"
                     /protein_start="527"
                     /score="19.5"
                     /tool="antismash"
                     /translation="LGIMKAGGAYLPLD"
     gene            21724..>23082
                     /locus_tag="C2142_RS41805"
                     /pseudo=""
     CDS             21724..>23082
                     /NRPS_PKS="Domain: AMP-binding (12-289). E-value: 2e-63.
                     Score: 206.3. Matches aSDomain:
                     nrpspksdomains_C2142_RS41805_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (395-453). E-value: 3.1e-21. Score:
                     67.4. Matches aSDomain: nrpspksdomains_C2142_RS41805_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="C2142_RS41805"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="AMP-binding protein"
                     /pseudo=""
                     /sec_met_domain="AMP-binding (E-value: 8.2e-78, bitscore:
                     260.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.4e-10, bitscore:
                     37.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRLDADHALIAAHSAEEPAGRVSDDQLAYAIFTSGSTGVPKAVG
                     VSHGSLAGYVAGVGARLGLPGGSRYAVVSTLAADLGHTVVFPALCSGGTLHVVPLDVAV
                     DPVALAGYFGRFPVDCLKVTPSHLRALLDGGGAAGVLPSGVLVLGGEVSDWELVGRVGG
                     LVPSCRVVNHYGPTETTVGALSFEVGGSVGGAGSVPIGSALGSARVYVLDEWLRPVPVW
                     ASGEVFVGGGGVARGYLGRAGLTAERFVADPFGGPGARMYRTGDRARRLADGSLVFLGR
                     VDDQVKVRGFRVEPGEVEGVLRRCAGVREVVVVARADGAGVVRLVAFGVWGAGVGEGEL
                     RAHCAGLLPEYMVPSVFVGLERLPLTGNGKVDRRALPEVVFGGASAVFEAARGPVEVAL
                     AGVWAGVLGVERVGRDDDFFALGGDSILSIQVVARAARAGLALTPKLMFRFPTI"
     aSDomain        21760..22590
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS41805_AMP-binding.1"
                     /evalue="2.00E-63"
                     /label="C2142_RS41805_AMP-binding.1"
                     /locus_tag="C2142_RS41805"
                     /protein_end="289"
                     /protein_start="12"
                     /score="206.3"
                     /specificity="substrate consensus: Asp"
                     /tool="antismash"
                     /translation="AHSAEEPAGRVSDDQLAYAIFTSGSTGVPKAVGVSHGSLAGYVAG
                     VGARLGLPGGSRYAVVSTLAADLGHTVVFPALCSGGTLHVVPLDVAVDPVALAGYFGRF
                     PVDCLKVTPSHLRALLDGGGAAGVLPSGVLVLGGEVSDWELVGRVGGLVPSCRVVNHYG
                     PTETTVGALSFEVGGSVGGAGSVPIGSALGSARVYVLDEWLRPVPVWASGEVFVGGGGV
                     ARGYLGRAGLTAERFVADPFGGPGARMYRTGDRARRLADGSLVFLGRVDDQVKVR"
     aSModule        21760..>23082
                     /complete
                     /domains="nrpspksdomains_C2142_RS41805_AMP-binding.1"
                     /domains="nrpspksdomains_C2142_RS41805_PCP.1"
                     /locus_tags="C2142_RS41805"
                     /monomer_pairings="Asp -> Asp"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       21808..21867
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS41805_0001"
                     /evalue="1.30E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="C2142_RS41805"
                     /protein_end="48"
                     /protein_start="28"
                     /score="27.0"
                     /tool="antismash"
                     /translation="AYAIFTSGSTGVPKAVGVSH"
     CDS_motif       22381..22470
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS41805_0002"
                     /evalue="7.40E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="C2142_RS41805"
                     /protein_end="249"
                     /protein_start="219"
                     /score="43.9"
                     /tool="antismash"
                     /translation="PVWASGEVFVGGGGVARGYLGRAGLTAERF"
     CDS_motif       22555..22620
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS41805_0003"
                     /evalue="8.70E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="C2142_RS41805"
                     /protein_end="299"
                     /protein_start="277"
                     /score="40.1"
                     /tool="antismash"
                     /translation="FLGRVDDQVKVRGFRVEPGEVE"
     aSDomain        22909..>23082
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS41805_PCP.1"
                     /evalue="3.10E-21"
                     /label="C2142_RS41805_PCP.1"
                     /locus_tag="C2142_RS41805"
                     /protein_end="453"
                     /protein_start="395"
                     /score="67.4"
                     /tool="antismash"
                     /translation="EVALAGVWAGVLGVERVGRDDDFFALGGDSILSIQVVARAARAGL
                     ALTPKLMFRFPTI"
     CDS_motif       22972..23001
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS41805_0004"
                     /evalue="4.40E-03"
                     /label="PCP_mC"
                     /locus_tag="C2142_RS41805"
                     /protein_end="426"
                     /protein_start="416"
                     /score="10.4"
                     /tool="antismash"
                     /translation="DFFALGGDSI"
     gene            23062..24562
                     /locus_tag="C2142_RS40800"
                     /pseudo=""
     CDS             23062..24562
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Epimerization (29-194). E-value:
                     1.4e-69. Score: 226.6. Matches aSDomain:
                     nrpspksdomains_C2142_RS40800_Epimerization.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="C2142_RS40800"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 1.6e-35, bitscore:
                     121.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRFPTIAELAPQVRAASGAAVADQGVASGPVPLTPIQRWFLEAE
                     PSSPQHYNQAVLLGAPRPLDPRALEEALRVVVTHHDALRLRLLRDGDGGWSLENAGLEA
                     LDRPLSATVDLSEVADAERPAAIEALATRVQTAVDLTAGCVLRAVRFTFGGGQDRLLLV
                     VHHLAVDGVSWRILLDDLATAYEQAAGGLPPAGQDHRLPHLGRATGALRALGGAAGGTR
                     LLEGGVGRSGPCRPARRRRAVGQHPRQRRDGDHRARRRGDRGPAAPGRRRRGHAGHAAD
                     RPGPDDRGLDRRAAGGPGLGGPRP"
     aSDomain        23149..23643
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS40800_Epimerization.1"
                     /evalue="1.40E-69"
                     /label="C2142_RS40800_Epimerization.1"
                     /locus_tag="C2142_RS40800"
                     /protein_end="194"
                     /protein_start="29"
                     /score="226.6"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLAVDG"
                     /tool="antismash"
                     /translation="GPVPLTPIQRWFLEAEPSSPQHYNQAVLLGAPRPLDPRALEEALR
                     VVVTHHDALRLRLLRDGDGGWSLENAGLEALDRPLSATVDLSEVADAERPAAIEALATR
                     VQTAVDLTAGCVLRAVRFTFGGGQDRLLLVVHHLAVDGVSWRILLDDLATAYEQAAGGL
                     PP"
     CDS_motif       23161..23190
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS40800_0001"
                     /evalue="7.70E-05"
                     /label="NRPS-E1"
                     /locus_tag="C2142_RS40800"
                     /protein_end="43"
                     /protein_start="33"
                     /score="15.4"
                     /tool="antismash"
                     /translation="LTPIQRWFLE"
     CDS_motif       23212..23313
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS40800_0002"
                     /evalue="1.10E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="C2142_RS40800"
                     /protein_end="84"
                     /protein_start="50"
                     /score="24.1"
                     /tool="antismash"
                     /translation="HYNQAVLLGAPRPLDPRALEEALRVVVTHHDALR"
     CDS_motif       23296..23322
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS40800_0003"
                     /evalue="3.80E-02"
                     /label="NRPS-afterE1part2"
                     /locus_tag="C2142_RS40800"
                     /protein_end="87"
                     /protein_start="78"
                     /score="7.3"
                     /tool="antismash"
                     /translation="HHDALRLRL"
     CDS_motif       23539..23604
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS40800_0004"
                     /evalue="1.10E-11"
                     /label="NRPS-E2"
                     /locus_tag="C2142_RS40800"
                     /protein_end="181"
                     /protein_start="159"
                     /score="36.8"
                     /tool="antismash"
                     /translation="LLLVVHHLAVDGVSWRILLDDL"
     gene            complement(24616..25506)
                     /locus_tag="C2142_RS33990"
                     /old_locus_tag="C2142_34065"
     CDS             complement(24616..25506)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021509.4"
                     /locus_tag="C2142_RS33990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34065"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_148646718.1"
                     /transl_table=11
                     /translation="MPSTDHQETGGTEQRHTPGPEPLGAGSLMWDIAGEYRSLLIVPSA
                     LLLQVAHPMVGAAVGDHSAFRADAWGRALRTGNSMLKYIYGGPVALSEGRRLRELHRSY
                     HGVDEQGRAYHALNGPAYAWVNGSLFERYVTARRLFGRPLDLAQQRQLYAESRQLGRVL
                     LVPEREMPPTVEEFRRYFRDMVTHRLENTATARTLLTALRHPPRPPDLPARLAPAWPAL
                     RETLGRLARLVTVGTLTPELRELLGLRWTGTDQRRMNALAAGVRAGHAILPERYQYMRD
                     VARVRSGELRPGAPS"
     gene            25735..26469
                     /locus_tag="C2142_RS33995"
                     /old_locus_tag="C2142_34070"
     CDS             25735..26469
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014134803.1"
                     /locus_tag="C2142_RS33995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34070"
                     /product="polyprenol monophosphomannose synthase"
                     /protein_id="WP_148646719.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.2e-23,
                     bitscore: 81.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEVAPKVVVVVPTYNERDNLPVLAGRLTDLLPNLHLLVVDDNSP
                     DGTGEVADKLAAESPDRVGVLHRTEKNGLGRAYIAGMTRALAEGADVVIQMDADLSHPA
                     SVMPAMVETLLGTDAAVVLGSRYVAGGSTAAEWPWHRKALSAWANIYVNTLLRLGVRDA
                     TAGFKAWRAETLRAIDLPSIRSNGYSFQVEMNFRTVRRGMRILEVPIRFQERVEGASKM
                     SLAVQIESALTPWRLLAGPGRR"
     misc_feature    26786..26800
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.91"
                     /tool="antismash"
     gene            26908..28152
                     /locus_tag="C2142_RS34000"
                     /old_locus_tag="C2142_34075"
     CDS             26908..28152
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013739.4"
                     /locus_tag="C2142_RS34000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34075"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_162002624.1"
                     /sec_met_domain="DAO (E-value: 6.6e-08, bitscore: 31.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARQTVAVIGAGVSGMTAAHILQRSFDVTVFEAKARLGGNADTRM
                     AGPFPADLGFVGFNELAYPNLMRLFAELGVMSKEAVQSADLICRDCEFAHMDGDTLGAE
                     GLPRRPRDASDATWQKFTEDLVRFGTELAELAGGGDDELTLGRLLRERSYSDYFTRHHL
                     YPRIGPWFLLHARDLDRIPARFLAATMSPLARPEARAAWRVVDGGSRTYVERIAAGLSS
                     VRVATPVRSVSRREGGVEVRDGADRVHHFDKAVVAVHPAQALRLLDRPTSAERAVLGAF
                     EYAKVEMVLHTDSSILPSDKLSSALMMEVSCASPRPFFSDCHVDVTKSQHLDTDVRYLK
                     TFNPTDTIDPEKLVAYETYEVPVFTRESVAAQRRLPEITDDVIAWAGAYHGNGFHEAGC
                     HAGVMAAEALGVSWS"
     gene            28223..29293
                     /locus_tag="C2142_RS34005"
                     /old_locus_tag="C2142_34080"
     CDS             28223..29293
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004004186.1"
                     /locus_tag="C2142_RS34005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34080"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_148646721.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.5e-49, bitscore:
                     166.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLDVPPVLDPSGIRSAVDELLHTFLDEQDSTATGPELLLFTRT
                     LRDLLDAGGKRLRPVLCVTGWQAVSHEPPPPVVIRAAASLELFHVFALIHDDIMDNSAT
                     RRGRPTAHRVLAGLNRHHPRAEALGANAAILLGDLTLGWSYDLLYREGSAEDRAAIPWA
                     VLNAMRTETLVGQYLDLQATGHRVPDVDAVWRVIRYKTAKYTFERPLQLGAMIGGADDG
                     QLRALSDYALPVGEAFQLRDDLLGVFGNPDHTGKPALDDLREGKHTVLVTTAYELATPA
                     QAGRLDAHLGDPELSHEAAEEVRAVLVDTGAVGVIEQMIADRRRRAVDSLAAAPLHSSA
                     RAVLDSLAAAATTRIA"
     gene            29322..30758
                     /locus_tag="C2142_RS34010"
                     /old_locus_tag="C2142_34085"
     CDS             29322..30758
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="C2142_RS34010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34085"
                     /product="cytochrome P450"
                     /protein_id="WP_148646722.1"
                     /sec_met_domain="p450 (E-value: 7.4e-91, bitscore: 304.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQELEIKARAVPGGIPVLGHVLGFAVWPLKFLDEQRELADITAI
                     NLGPKQARIVNNPTLVRELLVSRTKDFIKAGPLYDISSAFVGNGLAISEGAFHRRQRRL
                     MQPAFQRSRMPAYHSGMREAAEQMTARWRSGQAVDVHKDLFQLAVSVIGNMLYEGRFTD
                     EMTDRIVWAVSTASKGIGWRSVVPAAWTHTLPTEEFRRFTRAQQALHGLGDHVVAEYRE
                     RDDTDPEHFLSMLLAARDENGDPLSDKELRDEVVTLFSAGSATVATSLAWALHLLSIHP
                     DVEERLFTEVTEVLAGRPVTVADLPRLEYLGRVVTEVLRLYPPAWLLPRITPADTELGG
                     HPIPKGTYVFFSPYSIHHDARLYPDPEHFDPDRWLPERSASRPREAYLPFGAGIHQCIG
                     NNFALTEATIALATIVAKWRLRRPPRAKVGTRSAALLEPVGLTLVAKRRAGRTPAVAAS
                     APAVESPGCPVTAARPAADA"
     gene            30845..31951
                     /locus_tag="C2142_RS34015"
                     /old_locus_tag="C2142_34090"
     CDS             30845..31951
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="C2142_RS34015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34090"
                     /product="terpene synthase family protein"
                     /protein_id="WP_148646723.1"
                     /sec_met_domain="T1TS (E-value: 5e-44, bitscore: 150.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEELNPCPGIGQDTRVQFPVLAQRFTCGLHPEYYEILRRHEAWV
                     REKLLPGNPEAADQILRDNLSAMFVCMSYYNLDTERVLDICNLTDWLFIHDADVARLRT
                     TPDSSDVARQSAVDGYIGKLRGMLEGGAAPDEPWAMDSINDLITRFSAKCSTAMFGRLV
                     EAFNYYSLETIRDEASDLLSQKITDLDSYMEMRAAGGSSATLFYHVVTEYVLGVDLDRE
                     VLDDPLVQQYWQSIMDHWYLPNDLLSFRAECARGDHNNAVCLLRRFEGLSLQEAVDKVA
                     ALIDDRQDQAVRQYAEICASPLADHPGLLPVLETFQAISAANQRWSYMAPRYHGEGFVW
                     NGVLSGEVRLTPDHTYFPAVPITGEPTR"
     cand_cluster    30945..41922
                     /candidate_cluster_number="5"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="4"
                     /tool="antismash"
     protocluster    30945..41922
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[35944:36922](-)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="4"
                     /tool="antismash"
     proto_core      complement(35945..36922)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="4"
     gene            31999..32841
                     /locus_tag="C2142_RS34020"
                     /old_locus_tag="C2142_34095"
     CDS             31999..32841
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (34-224). E-value: 6.8e-39. Score:
                     125.2. Matches aSDomain:
                     nrpspksdomains_C2142_RS34020_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014414.4"
                     /locus_tag="C2142_RS34020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34095"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_148646724.1"
                     /sec_met_domain="PCMT (E-value: 4.5e-09, bitscore: 35.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEGSIASFVPTKDDIAAFYDNSIPLINQLVGNNVHVGYWTSSED
                     RSSLQKATDRMTDIVIERLAVKPGARVLDVGCGLGAPAIRLAKAAGVHVVGIATSPKLI
                     DEAREAAQQAGLADQVTFEVVDAEEMDYPDESFDAVMAIESLVHMNDRPRAFGRIARVL
                     RPGGRLVLTDRVEIATPTEQQREVVEAYRRLSMNSPFLKLDEYIRFLIEARLLPVEYRD
                     ITPETMAHQLHLLEAIEQETAGSATSLDPAVLSAGKSVFTGLFEARLPTNMLIVAERG"
     aSDomain        32101..32670
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS34020_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="6.80E-39"
                     /label="C2142_RS34020_oMT.1"
                     /locus_tag="C2142_RS34020"
                     /protein_end="224"
                     /protein_start="34"
                     /score="125.2"
                     /tool="antismash"
                     /translation="VHVGYWTSSEDRSSLQKATDRMTDIVIERLAVKPGARVLDVGCGL
                     GAPAIRLAKAAGVHVVGIATSPKLIDEAREAAQQAGLADQVTFEVVDAEEMDYPDESFD
                     AVMAIESLVHMNDRPRAFGRIARVLRPGGRLVLTDRVEIATPTEQQREVVEAYRRLSMN
                     SPFLKLDEYIRFLIEARLLPVEYRDIT"
     gene            32925..33806
                     /locus_tag="C2142_RS34025"
                     /old_locus_tag="C2142_34100"
     CDS             32925..33806
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172811.1"
                     /locus_tag="C2142_RS34025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34100"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_148646725.1"
                     /transl_table=11
                     /translation="MDQATLDRQYSPSSRVPSLQAYLDEYAQLSETARRSHPVHTALAY
                     GPHPAETLDYFPAVAGRPGGRREPPPLQVFVHGGNWQALSRSESAFPGPALLRAGAAFA
                     VVNYGLAPATRLDDMVGMVRRSIGWLVRNADELGFAADRLHVSGHSAGAHLIAMALLPD
                     SSDGPFEGPDVSGRIAGAALLSGMYDLEPVRLSYVNDALSLDEAGAHRNSPLHRLPSRL
                     PPLIIARGGNETEEYACQQDRMAQALRPRTSLTEIVAAARDHFSIPYDLGAGGTALGDA
                     VLAQMGLGGTTA"
     gene            complement(33966..34748)
                     /locus_tag="C2142_RS34030"
                     /old_locus_tag="C2142_34105"
     CDS             complement(33966..34748)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966065.1"
                     /locus_tag="C2142_RS34030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34105"
                     /product="isoprenyl transferase"
                     /protein_id="WP_148646726.1"
                     /transl_table=11
                     /translation="MKLLPLFLRRQMEAVYERRLASTLEGLPRPKHVGIMLDGNRRWAR
                     QAGHEDVREGYRAGGAKAAEFLGWCTAAGIEHVTLFMLSDDNLGRPAEQLGPLIEIIEE
                     TVRNIAAEDCPWEVQVIGSLDLLPGDSARVLKEAAAATAGRGRLKVDVAVGYGGRREIV
                     DAVKSAFEQHIAAGGDPVDLIERFDVEDISRHLYSPTADRTDFIIRTSGEQRLSGFLLW
                     QSAYAEMHWVDCYWPAFRRVDFLRALRSYAGRERRFGK"
     misc_feature    complement(34821..34837)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.55"
                     /tool="antismash"
     misc_feature    34821..34838
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.84"
                     /tool="antismash"
     gene            complement(34914..35888)
                     /locus_tag="C2142_RS34035"
                     /old_locus_tag="C2142_34110"
     CDS             complement(34914..35888)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012554.4"
                     /locus_tag="C2142_RS34035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34110"
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="WP_148646727.1"
                     /transl_table=11
                     /translation="MVPIDFGTGRLGDEIPAWLSVQPMKRRFYGLDLYFREGWEDLAAA
                     GPAEVVRGWLDRHTVLLCKPDAVVGRELETVFEWLARHDARVVAAEITSGGRHVIRALW
                     EFQWNIATRDRRDVTELFMERTPMLLLVVRMPAGALPASVRMAGLKGSANATDRAPHQL
                     RSSLTTTNYILNGVHSPDEPADVVRELSVLLDERQRRRVIQAIRTGSEESPRAKAERLY
                     AQTPGEPALDLVSRRSRWLEAIGSAGRDGVVHADEDARLRGLLADVESGRRDWRDFVTA
                     MEDAGIPWDAWDTVVLGTALADAHVPDRLRILPGASPAEWSRG"
     gene            complement(35945..36922)
                     /locus_tag="C2142_RS34040"
                     /old_locus_tag="C2142_34115"
     CDS             complement(35945..36922)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015700.4"
                     /locus_tag="C2142_RS34040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34115"
                     /product="AfsA-related hotdog domain-containing protein"
                     /protein_id="WP_148646728.1"
                     /sec_met_domain="AfsA (E-value: 6.8e-15, bitscore: 53.7,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVQAIAHRQTIPRELVHKWSIDEVFITDFSVTSDREMLMGVQLP
                     RAHSFYCEYPLQNHQPDLALLVEVCRQACFVVAHSQFGIPVEGNDYQFLFQELDARLAD
                     EKPLDTTRPVNAVLESTVEREWRRGRVLSGLLWNFVIRVDGAKVADVRIRMTWIKRTTW
                     REMRNFMRKGRELPIQLVFPEPPTTTVSPQEVGRVNPENIVLADLALADDVSTATVRAD
                     IRHPVLFDHPIDHIFGMVQLEAARQLALATISRRTGTPAAELEMTACATSYTSVAEFDL
                     PTELRARVGTEDDPAKTYLGTPLTIDVVQGARPVSRFDLRVRAR"
     gene            complement(36961..37983)
                     /locus_tag="C2142_RS34045"
                     /old_locus_tag="C2142_34120"
     CDS             complement(36961..37983)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF000361.1"
                     /locus_tag="C2142_RS34045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34120"
                     /product="FomB family phosphonate monophosphate kinase"
                     /protein_id="WP_148646729.1"
                     /transl_table=11
                     /translation="MTAPFTGPPAAGPPPGPAIRSTSVVDLNLIRIRLCSNLESPPARS
                     YFTRFAADDAAADFEIRCYDLDRDKVDVEAVRHLVDSTVRAKRFTKGYYRGPYFGDPVY
                     LVTRGRTFHVYGRSLEKLVWPYFIKHILSVHAAENGLLDLKAAGFTLNGDGTLLFGQTG
                     GGKSVFLAQACLGGAQFLSNTHMLVRGVTAHGVPSAMRVRRDACFGELIDRHRLPRHIE
                     EGEYISSPEILFGKPATNSAPVRNIVIVNSRQDTPAGFHQVDPGTALPFLDQFGLGVTT
                     YGLKDDLIAHFGYDVQRYAKHYNTMQKTLAGLCENARCYVSNVDMMDPSARAAVLSDLQ
                     "
     misc_feature    complement(37989..38004)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.06"
                     /tool="antismash"
     gene            complement(37996..39837)
                     /gene="asnB"
                     /locus_tag="C2142_RS34050"
                     /old_locus_tag="C2142_34125"
     CDS             complement(37996..39837)
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143399.1"
                     /locus_tag="C2142_RS34050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34125"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_148646730.1"
                     /sec_met_domain="GATase_7 (E-value: 3.3e-44, bitscore:
                     148.6, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 3.9e-91, bitscore:
                     305.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGVTGWVDFGRDLSREYEILRAMTDTLACRGPDAEGTWLDRHAA
                     FGHRRLAVIDIEGGTQPMLGGTGAAGQIVLTFSGEIYNFRELRQELASFGHEFRTKSDT
                     EVVLRAYLQWGASFAERLNGMFGLGLWDPRSQELLLVRDRMGIKPLYYFPTRDGVLFGS
                     EPKAILANPLAPREVDADGLREVLDMVKTPEHAVFRGMYEVRPGHIVRVTRSGLTKHRY
                     WSLEARPHTDDLDTTVRTVRELLEDTVRRQMVSDVPLATLLSGGLDSSAVTALAAGTVG
                     PGRLRSFSVDFSAASDRFEPDAVRLEADAPFARELARHVKADHTEILLDSRELLDPAVR
                     SAVLRATDLPPAYWGDMWPSLYLLFQAVRQHSTVALSGESADELFGGYRWFHNPRAVKA
                     DTFPWLTSGSSRYFGGLRLLDSGLLEKLDLPGYREARYREALDEVPALPGEDGLERRMR
                     EITYLNLTRFVQTLLDRKDRMSMAVGLEVRVPFCDHRLVEYVANVPWSMKSFDGREKSL
                     LRAATADLLPASIVERNKTPYPTTQDPGYERGLRKETAAILADRSAPVHLLLDAGKART
                     ALDRPQGVVSRSYDRGSLELAVWLNRWLTEYNVTLTI"
     gene            complement(39914..40189)
                     /locus_tag="C2142_RS34055"
                     /old_locus_tag="C2142_34130"
     CDS             complement(39914..40189)
                     /NRPS_PKS="Domain: PP-binding (31-78). E-value: 1.5e-09.
                     Score: 30.1. Matches aSDomain:
                     nrpspksdomains_C2142_RS34055_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129: acyl carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018531585.1"
                     /locus_tag="C2142_RS34055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34130"
                     /product="acyl carrier protein"
                     /protein_id="WP_148646731.1"
                     /sec_met_domain="PP-binding (E-value: 1.1e-08, bitscore:
                     34.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEFSLDRLKQLLQECGEQDESVDIDLSGNIDDVAFDDLGIDSLA
                     LFNIFVMIEREYSVGLSYDVGIEAETPSQLVQVVGRAIAAAAHGKP"
     aSDomain        complement(39956..40096)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS34055_PP-binding.1"
                     /evalue="1.50E-09"
                     /label="C2142_RS34055_PP-binding.1"
                     /locus_tag="C2142_RS34055"
                     /protein_end="78"
                     /protein_start="31"
                     /score="30.1"
                     /tool="antismash"
                     /translation="DDVAFDDLGIDSLALFNIFVMIEREYSVGLSYDVGIEAETPSQLV
                     QV"
     cand_cluster    40343..52345
                     /candidate_cluster_number="6"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="5"
                     /tool="antismash"
     protocluster    40343..52345
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[45342:47345](-)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="5"
                     /tool="antismash"
     proto_core      complement(45343..47345)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="5"
     misc_feature    complement(40395..40410)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.91"
                     /tool="antismash"
     misc_feature    40438..40456
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.77"
                     /tool="antismash"
     gene            40446..41636
                     /gene="dxr"
                     /locus_tag="C2142_RS34060"
                     /old_locus_tag="C2142_34135"
     CDS             40446..41636
                     /EC_number="1.1.1.267"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dxr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010262070.1"
                     /locus_tag="C2142_RS34060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34135"
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="WP_148646732.1"
                     /transl_table=11
                     /translation="MKTVGILGSTGSVGTQAVDVVRRNTDKFKVLALAAGGGRVGLLAE
                     QVLDLSPVVVAVAGEGAADELPAALAAEASRRGLSATDWSVPKILSGPAGVEEVAAYPV
                     DVMLNGITGALGLTSTLATLRAGTTLALANKESLIVGGELVKREARPGQIVPVDSEHSA
                     LAQALRAGAREEVRRLVLTATGGPFRGRGRAELADVTVAEALAHPTWSMGPVISINSAT
                     LVNKGLEVIEAHLLFDVPYEDILVMVHPQSTIHSMVEFVDGSTIAQVSPPDMRLPIALG
                     LSWPERVPGAARAFDWTQNQSWELFPLDDEAFPSVGLARHVGSLGGSAPAVFNAANEVC
                     VDAFLAGRLPFLSIVDTVARVVSELGDPAADSLETILAADAWARARAQELNGAAHR"
     gene            complement(41802..42758)
                     /locus_tag="C2142_RS34065"
                     /old_locus_tag="C2142_34140"
     CDS             complement(41802..42758)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS34065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_34140"
                     /product="hypothetical protein"
                     /protein_id="WP_148646733.1"
                     /transl_table=11
                     /translation="MEIVEQDGLVVALVDQQEAASRTWTTCDRPVDIARLTGSEGLDGA
                     ALAELGFTARPRWVNWCAQVRDSEEEFESGLSRTERRNGRLARRFVQEQQLRAEVRQGL
                     AEDVLDAFLDVYDEQIAGMPRGKNFARRERERLLAAAPDHVSVCVYAGEAMVAGSLWRV
                     RRGESVLQMRFSAASADARSGRVMRAAYGEAFRFARDHGLEFASLGNDPSLFGHVVQPG
                     LFNFKSRLGFGVVPSQVLDPNLAGEFADRFLSLRSLSDPSLVVTWGGRRGEPLSWPAAA
                     SSPGHDLLLLSGKPEPGLLDAFNGDGFRERRLLVVSS"
     gene            complement(42745..43971)
                     /locus_tag="C2142_RS34070"
                     /old_locus_tag="C2142_34145"
     CDS             complement(42745..43971)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="C2142_RS34070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34145"
                     /product="MFS transporter"
                     /protein_id="WP_162002625.1"
                     /transl_table=11
                     /translation="MAEHAAPTPATDSRILRILIASSISSKVADWQLGIVVPLAVLKQT
                     DSVAMSLISFSLRGITYIWSPFLGALIDRFDRRAVFALAQVQQAVCLALLAVSLNSQVS
                     VALLVLLSGFGGVASNITGQFVLIPKLISAPARPAAVAKLNSAIEFSKVGGLLIGGAAF
                     SALGPASASLCIAALYSGAALLALLLPRVPASYQKMSIRRDVAMGFRWAVKPEIIWLVV
                     TMSMTNLAIGQLEPVLVTEFGQQGINAKVISGVMAIGLFAGAVASRMAPRILPAWSPER
                     RILACQVTALAGLVLVATPALPTKLTGYVFECLAVAVSNVASITYRQETIPVEVAGRAN
                     ATIRMFITGAVPLSGFLFAGASRLDGYLRWLPALGIWTVAVVIWAVYTRHSERLPAVDA
                     LEGAGVGDR"
     gene            complement(44057..45328)
                     /locus_tag="C2142_RS34075"
                     /old_locus_tag="C2142_34150"
     CDS             complement(44057..45328)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080: lysine/ornithine N-monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024826.4"
                     /locus_tag="C2142_RS34075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34150"
                     /product="SidA/IucD/PvdA family monooxygenase"
                     /protein_id="WP_162002626.1"
                     /transl_table=11
                     /translation="MQSFDAVGIGVGPFNLSLAALAQSAGGLTTRFFDVKPRFQWHPGL
                     MLPEADLQVSFLKDLVTLADPTSAYSYLNFLHHKGRIYSALIANGLNSSRMEFEQYYQW
                     VAEQLPSIRWDQSVKSVTLGDGCFEVTCESGETARTTTLALGSGKEPHLPDFAVGLRGG
                     QVLHSSDLMQVRPATSGRRVMVVGGGQSGAEVVNYLLSDDTSLPESLTWVSSRAGFLPM
                     DDSPFTNEWFAPSYVDHFRSLSAERRAVVLGSQRLASDGVSESLLRKIYRRLYQLDIAG
                     GPLRHRLVANHRVADLRREGEALVVDLHDADRNRQEHCTVDVVVFCTGYRSRFPDYLEP
                     LRERITVRADGFEVHEDYSLEWDGPSDLRIYVQSFAENSHGIADPNLSLSAWRSARILN
                     SILGREQFRVNGATSITSWALGQD"
     gene            complement(45343..46524)
                     /gene="aepY"
                     /locus_tag="C2142_RS34080"
                     /old_locus_tag="C2142_34155"
     CDS             complement(45343..46524)
                     /EC_number="4.1.1.82"
                     /GO_function="GO:0033980 - phosphonopyruvate decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aepY"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006345250.1"
                     /locus_tag="C2142_RS34080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34155"
                     /product="phosphonopyruvate decarboxylase"
                     /protein_id="WP_148646736.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.3e-11, bitscore:
                     43.2, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4e-18, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISNDNFCDTLQEHGVTFVAGVPCSYFSGPIERLTREGKYLPAAN
                     EGAALAAAAGASVAGRRSAVIAQNSGLGNLINPLTSLVQTYGIPVLVFMSLRGWPDPSE
                     DEPQHAVMGTATHKLLDAVGVPHITVPADATELGSALDRAEEHLAARRSVFVLAQKGAI
                     ESHRPEAHPVVTGVSRVEVLRAIEPLLGDAAVVSTTGYTSRELFGVTGSKNHFYMQGSM
                     GHAAAFALGVALQSTARPVVVLDGDGAAIMHLGTLSSVGACAPAGLVHLVFDNGTYEST
                     GGQATTSHSTDFAGVARSVGYVSAQECRSVDEVTAALAKALRSSGPHLIVAKVAGGGTS
                     TFSRATAAMTTDEIRDGFAARLETEHRSGEASLTNSHVDPSAPAVRPPGRDRP"
     gene            complement(46521..47345)
                     /locus_tag="C2142_RS34085"
                     /old_locus_tag="C2142_34160"
     CDS             complement(46521..47345)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135402.1"
                     /locus_tag="C2142_RS34085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34160"
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_148646737.1"
                     /sec_met_domain="phosphonates-like (E-value: 1.2e-110,
                     bitscore: 367.6, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.7e-61, bitscore:
                     206.0, seeds: 69, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.2e-93, bitscore:
                     312.2, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQGGLVRVAGAHDALGSTLAWQAGFQAVWASSFEISASRCLPDA
                     SVLTMTEYLAAATNMQKAVGIPVVADVDTGYGNNLNVAHMVREYEAGRITAVCIEDKVY
                     PKVNSFAATSHDLLPVSDFARRIGTAKAAQRGEDFYVIARTEALINGLGVEEALKRCYA
                     YAEAGADAVLIHSKKKDQQEIVEFLDGWDGRLPVVVVPTTYPQWSAAEAEKHGASVVIY
                     ANQGLRATVQALRETFRTICQDGTSLGVEDVIAPVSDIFALQKLDEWLALEA"
     misc_feature    complement(47878..47893)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.61"
                     /tool="antismash"
     misc_feature    complement(47942..47959)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    48193..48209
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 24.84"
                     /tool="antismash"
     misc_feature    complement(48226..48240)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.24"
                     /tool="antismash"
     misc_feature    48298..48307
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.59"
                     /tool="antismash"
     gene            48317..49594
                     /locus_tag="C2142_RS34090"
                     /old_locus_tag="C2142_34165"
     CDS             48317..49594
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS34090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_34165"
                     /product="hypothetical protein"
                     /protein_id="WP_148646738.1"
                     /transl_table=11
                     /translation="MAAQTIAGGTGSGAVVTRHLVVGDVSHQYSVTPDPVAPLLVAELT
                     TEPGGATRAMEFLRRPETASSTVSVIGAAGQAGTVTLGRVPVELWASFGVTPEFEAQLR
                     GALEAAGSQELSGVDLSALAPLMLLRTHRGAERPFTEVLMCGRVRSLGTLFVRVARFAH
                     AAESGIAELVSGALELSASLQDNVRIEGNAYTSYEKGIEIEQKVNVYDEVSIWSLTQSL
                     WSAVENGEFNGFITDPGYELTRWHFIQHNFEVTAPASEVGHIAFQETPSGTYQLKLKRF
                     AEDALRREEIVYKGIDIPGADFSGYLRREYPDIEFRRLPSLTRTRFDINVQSVITGNYF
                     GIETDEVLVLDPRGPKLRQVEMEYLETRWHEGMDPSTIDDDMNRLTELVEEHLAKRGIA
                     AERTFYSKLSFLKDCVRRSDQDVLGV"
     misc_feature    complement(49602..49611)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.19"
                     /tool="antismash"
     misc_feature    complement(49615..49631)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.17"
                     /tool="antismash"
     gene            49668..50894
                     /locus_tag="C2142_RS34095"
                     /old_locus_tag="C2142_34170"
     CDS             49668..50894
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1291: argininosuccinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006345246.1"
                     /locus_tag="C2142_RS34095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_34170"
                     /product="argininosuccinate synthase-related protein"
                     /protein_id="WP_241002939.1"
                     /sec_met_domain="Asn_synthase (E-value: 3.7e-09, bitscore:
                     35.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTSTRLVRSFRDITGGDTDLRRPVVTLFSGGLDSTYLLYRLARA
                     GATDVRAISVGLGGDEQAAQLQRIADKLGVQVQVTDAREEFVDEFVRPAIAAHAVYLDT
                     HPISSSLSRPLIARVAVGAAREHDAQMILHTANRSQNTLRRLNGALELLGFQGRFGSPY
                     DLNPVDREVKIKELQSVGLDEMAERSASGDSNLWCREFESGILDDPEDHVVPESYYRWS
                     ARRGVAPAPEHLEIGFRQGIPVAVNGEELPLAEIIERLNWTVGAHGIGRYTGLEHLPGG
                     VKVLEVREMPAARLLMASRRHLETAVLEAESLREKMHVEQVWVREALEGRWFGELRRAC
                     DSFIAELVASVTGTVRWRLSARGASTTSIVAASPRYVRNREDWEQASIQAEISHYEAAS
                     DGDIRGGKW"
     gene            50888..51346
                     /locus_tag="C2142_RS34100"
                     /old_locus_tag="C2142_34175"
     CDS             50888..51346
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS34100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_34175"
                     /product="hypothetical protein"
                     /protein_id="WP_148646740.1"
                     /transl_table=11
                     /translation="MVTNQKSNGSARQLVVIDADARAARAARTLGCRIVYVQQPGSPVH
                     ELVDDDSGYYSVDFTGPKFAGFVGEVLRPLLPTAAVSLTAQGLAAADVVNSLLGTAGTP
                     PGILQRLTGTGPESSDGLDLVRLALGWPLGLREADCTVPARTLEGDGQ"
     misc_feature    complement(52273..52284)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.05"
                     /tool="antismash"
ORIGIN
        1 cgcgctgccg ccgatcaacc cgatcggact gccggcggcg acggcctgac ggccggctcc
       61 acccgaccgg gtccgcccgc ccaaggccgc ccgaggccgc ccgagttcag cagagtccgc
      121 ccgagtccgc cgcagttcgc ccgcccgggg tcatccgtcc accccgggcg ggccgagcac
      181 gatgccccgc cccgcgtaga accgctcgaa ccgctgccac ggcacgtgcg cgtacgcctg
      241 cgactcgccc gcgaagccgg acgggttgtg gatcaccagc gccgtcgccg tggtgcccac
      301 cgccaggacc aggtggccac cgcgccgctg ggggtcgggc ccgtccgggt gccggatcgc
      361 ggggtggacg gacagcatga ccagccgccc ttcggccacc tccgcggcca cctccgccgg
      421 cgtcaactcc ctcgcctgcg cggtcagtcc ccaccgctgg tggacgtagg cggcgaacgg
      481 tgtgtggatc aggccgcgca gccgctcgcc gtcccgctcg tacgcgccgg ccgccaggca
      541 ctcctccgcc agctgcaccg ctgtcggcgc caccccccac cagtggtcca gcgccatccg
      601 caggcaggcc accccgcaca gtcgccacga ccagtactcg tactcctcgg gcgtggccgc
      661 ccccgactcg ccccagcgcg gatcgtccgc cgcgctcacc gcgccggcca cgatctctcg
      721 taccaggccc gccgactccc actgcgcgta gtacggcacc tcgtgcacca cggccgggtc
      781 gccgccgctt ccttgctcca ccgtccccat cccccgacgc tctcacgccg ggcgggcgat
      841 gccgccccgc gacactcacc ccggccccgc aaggccaacc ccgacgacgc cccgaacgac
      901 gcccccagca acgccgccac cgactccgcc taccgactcc gccaccgacg cgcacgccca
      961 cgccgccccc gctcgcgctc cgatgccgcc ccgccgccga gggctgtcag tagtgcccgc
     1021 tagggtcatc ccgatcattg ggatcatgga acaacgaggt gggggcgggt catgggcatc
     1081 gagcaggact gggacgggcg cctgcaactg gagccccagc agctcccgga gcgcctctcg
     1141 cacctgccga gccgggagtt cctgatgcag gagggcctgc ccgaggccgc ggccttcctc
     1201 gacttctcgg ccctggactt ctcgcccctg gagcccttcg ccaaggacgg gggcaccggg
     1261 cagcacctct tcgtcctcgg cgagaccgcc tacgccgccc cccggtccca cgagggcgac
     1321 gcggtggtgc tggacggggt gaccggtcag gtcttcctca tcggccgccg ccgcggggag
     1381 ctccgccgcg acctgctcgc ctccggcctg tccgccctgg tcgagctgat gcgcgaggtc
     1441 gacgtggcgg ccctggcggc ggaggagccc gaggcgctcg gcggcgagcg cgggccggcg
     1501 atcgtcgcgg aggtggtcag ggtcgtgcgc gagcggctgc gcgcgatgga cccggagctg
     1561 ttcgcgcacc accgcgccgc tcccccgcac tgggagaccg ccctgctggt gcgctcactc
     1621 gcctggggtg cgctccccgg cgggccggcg aggctcgcat acgagttcgg gccggagctg
     1681 gccgaggacc tcgccgccgt caccgggaac gggcaggtcc gccgcttccg cccggaggag
     1741 ctgcccggcg ggctcaccca cgggccgacc cgccggctgc tcaccgacgt cggcctgccg
     1801 ctcggcggcg ccctgctggg cgtggccgac gacgggccac tggtcacgat ggtggaggcg
     1861 taccccgagt acttcgcgcc cgagtacttc gcgccgggca ccggcaccgg cgacgagcac
     1921 accccgggcg gagaccccga gaacgacccc gacagcgacg gcgacagcga cagcgacgag
     1981 tgggagcgcg accaccagcg ccaccacatc gccctcgccg cctggccgca cgacctggag
     2041 atcgccctcg acggcgccac cggccggttg gagctgcccg cctggaacga ccccggcata
     2101 cccgaggcct acctcaacca ggacgtctcc gcgctcctct acaccctctg gacgtgcggg
     2161 cggatgcgcg ccgagtggcg gcgctgggag cacggggccg ccggcgaggc gtgggcgctc
     2221 ttcgatccgc aggcgctgct gagcggtgtc gtcgagggtg tgctcgccgc cctcgacccg
     2281 ggcgcgttcg ccacccccga ccactcctgg cagctcctcg ccgacgacca ctccatgggc
     2341 ggcctgctcc actgagccgc cctacggggc tcgccctacc gggccttctc ctctgccgcg
     2401 gcggcctccg gaacgccctc ccccttcgac cggaaggcga accggtccgc cgcccggcgc
     2461 ccgcggcggt ccaacggcag cgagccggtg gccgccacca gcccgaacgg gggcatgtcg
     2521 aagtagatcg actcgtagga cccctcgggc acgacgtacg tctcgtgcca gagccccacg
     2581 tgctgccggg ccttcccgcc ccgcaccttg cggttgacca tgccccacgc cttgtggtgg
     2641 aacgcgtccg gcgcggcggc gtacgcgtac agcttctcct tcgactccca gtactggacg
     2701 atgtagtacg tgcgtggcga ggccgtcagc atgacgcggc cgcgcagtcc gcgttcgggg
     2761 gccttggcga gctcggacag catccggaac atcgccatca tcacgggccc ccagtggtgg
     2821 acggcccaga agcggttgat gcgcattcct atcagcagca ccaccgtgtc tcccgtggcg
     2881 gccgcggtgg tgtatcccgg agtcggtttg gcgaacacgt ctgcctcctg ctgcccctgg
     2941 tcccatgtaa gcggtgatta catcagcggg cgacaacccg gtcaaggctt cgcgcaggac
     3001 ccaaatcccg tgcggtcagc ggggattggc cactccctgg ccgaacgtgt ccagcacctg
     3061 cgcggccagc tcctccgccc gctccggcgg caggcagccg tcgatgatca tctgtgagag
     3121 cccgtacacc agggcctgcc cggccagccc cacgagcgcc ggatcacccg ggcgcagccg
     3181 gccggcctcc tggtccgcga cgatgaaacc ggtgaacgcc tcgtcgatcc cggacagccg
     3241 ccgctgcaac tccggctgcc gcgacggcgt gaacacccgt gcccggacca gctcgaaccg
     3301 gtgcggatgc cggatcgcgt accggacgaa gcccagcccg atcgcccgca gcgccgaccc
     3361 ctcgctcccc tcgatctccg cccgctgcca ccgctcgaag tccgccagca cctggtccgc
     3421 caactccgtc aacaacgcct gccggtcggc gaagtggcgg aacggcgccc ccgccgaaac
     3481 ccccgcccgg cgcgccacct cccgcatgct gaccgcgccc agcccctgct cgtccaacac
     3541 ctcgaacgcc gccgccacca gcgcctccgg cagcgcccca tggtgataac tgccacgccg
     3601 ggcaggcctc tccgtcatgt cagcagtgct accacaggtc agcgcccgga agctcccggc
     3661 aacgccccac cgcgcgcgat caggccgaga ccgcagccgg ggcaggtggc cggagctcca
     3721 ggaggtggcg catcacctcc gccggcagcg ccctgttccc ggcggcggag tcggccgtcg
     3781 ccgggtcgtc caggagaccg gcgaggacgt gggccgggag gcgcgaatcg ccggcggccg
     3841 tgctgcggat gccgtcgtgc gggtcgtcca gcagccggat cacggacgcc acggagagac
     3901 gcgggtcccg cagggcgcgc cagcggacgc cgtacgcggg gtcgcggctg aggcgttcga
     3961 ccagctcctc ggtcgagtcc gggtcgtcca gggcgagttc gcgcatccgg gggtgcgggt
     4021 ggtcggcgtg gcggagggtg tgctcgcggg ggaagttggg gtgttcgggc atgcgggcgg
     4081 cggagtagcc gtcccaggtc cgccacatct ccgacagcag ctcggccggg gcctgggcgc
     4141 agctctccgc caggagcagc cggacggcgt ggtcctcgtc gcgggcgagg aggtcggcca
     4201 cgtcctgggg caggttcttc gcacaggcga cgctgcggcg caccaggaag tggcgggagg
     4261 cggcgaggcg gcgcatcgcc gcggggtcgt cctgctgctc ccggacccag tcgagcacgg
     4321 ggatgcggac ggccgggtcc ttgtcgaacc ggataccggc gcgctgctcc tccgggagtt
     4381 cgggccgcag ggagacccgc cagcggacgg aatcgtcggg gtcctgcccg aggacggcca
     4441 ccaggtccgc gtccaggccc gcgttccggg cgacggcgcg gcgcaggccc acatccgggc
     4501 cgtgggccag cgcttcggcc agctcgcggg tgagggcgca gcgctcggcg gcccgtccgc
     4561 ggtcggagct gtcgggcagc gcgtcgaagt cggcggcggc gagcggaacg gcctcgtggt
     4621 ggcgcagccg tgccgtagcg cgcaccgggg cgtccgggtc cgcgaggagg gccgcccggg
     4681 tggcgtcgtc caggtgcggc caggcgcgcg gcgtcaccct ccggcggacg gacgcgtcct
     4741 ggtcggcggc gaacgcgatc aggtgccgtg tgggaaggtc gcggtggagc gccagctcgg
     4801 accggatctg gtcgctcgcg tcggccgcca agaggtcgta ggtggcgtcg gtcaactcca
     4861 gcccggcgtc gaccagcccg accagcagga tccagcggag ccgggcgtcc gcctcccgga
     4921 agagccgctc gcgctgcgcg ggcgtgaggc tcgtccgctc ggcgaggagc ctgcggacgc
     4981 gcggacgggg gtgggcgatc cacgcgtcca cgacgtcgtc gggcagctgc cggtagtgca
     5041 gcccgaaggg cacccgctcg tccggggcgc cgtggaggag ccggatcagg acgtccgcgg
     5101 gcgctgcgcg gttgccggcc aggccgtcgc gccacttgtc acgcagctgt ggcgaggtgg
     5161 tggttcgcgc cagcaccggc tcccacacag cccggcggcc cgcgtccccg ctccggtccc
     5221 cgcccgcgtc cccgctccgg tccccgcccc cgtccgcggc ggcgcgggcc cgggccgacg
     5281 cctccagcca cgcgctgagc gcgcggacga ccaccagccg gaccgcgccg gcctcggtgg
     5341 cgcacccgag cacgcgctcc ccgtcgaggg aggtggtgac gaactccggc ccgcccgact
     5401 gccggccgag cgccccggcg aggtcccacc ggtcggagag ccggacccgg gaccatccgc
     5461 ggtggcaccg gcagcccgcg ccggggatgt cggggacgtc gatcaggaac gcgccggctt
     5521 caccggacgg cccctcaccg tcgaacggcc cgcccacgcc ggacgacccg tcgtcggacg
     5581 acccgtcgtc gggcggtccg cccacaccgg acgacccgct ctcgtcaccg gacgacgcac
     5641 catgaccgga cgactcgccc acgccgtcgg acggcccgcc tcgctcgaac accccacgct
     5701 cgaacacccc gtgctcgacg gcgagacggt gccactgccg gttgagttcg gcggcgaggt
     5761 ccgggtggtc ggccggcacg acgaccgcgg ggtggtcggc cccggcgcgg accgcgcgcc
     5821 aggccgccgc gaccggccgc gcccccggga cccctcggct cccgacccgc tccagcccgg
     5881 cccggtccag tacgtcgtcc agctcactgc gtccacccgt catgccgatc atcatcgcgc
     5941 acggatgtcc gcaggtcggg ggcggaggcc gtccgggccc cggcccccga cagaggcgcg
     6001 gctaccaggc gtagtcctcc ggggccggct tgtggccggg gaagagttcg tccagccggt
     6061 cgagcgtctt ctgggcgagt ttgaggtcga gcgcgcccac cgccgcttcg aggtgggcgg
     6121 gggtgcgcgg gccgatgatc ggggccgtga cggccgggcg gctgagcagc caggcgaggg
     6181 cgaggtcggc ggggtcggtg ccgagttcgg cggcgaggtc ctcgtaggcc tggaggcggt
     6241 cgcggttggc ggcgaggatc tcggaggcgt ggcccatggc gccgcggacg gcggtgccct
     6301 cgcgttcctt gcgcaggacg ccaccgagga ggccgctgcg gagcgggctc caggggagca
     6361 ggccgaggcc gtagtgctgg agggcgggga cgacctccag ctcgatggtg cggtcgagca
     6421 ggttgtagag ggactgctcg ctgaccaggc cgaggaagtg gcgggcgcgg gcggcctcct
     6481 gggcctgggc gaggtgccag ccggcgaagt tgctggagcc gacgtagatg atcttgccct
     6541 gggtgaccag gacctccatc gcctgccaga tctcctccca gggcgtgtcc cggtcgatgt
     6601 ggtgcatctg gtagaggtcg atgtggtcgg tgttgagccg gcgcaggctg tcctcgaccg
     6661 cgcggcggat ggcgagggcg gagaggcggc cctcgttggg ccagtcgccc atcggggcgt
     6721 aggccttggt ggcgagcacc gtccgctcgc ggcggccgcc gccccgggcg aaccatctgc
     6781 cgatgatctc ctcggtgcgg cccttcaggt tgccctcgtt gtcgcggccg taggcgttgg
     6841 cggtgtcgaa gaagttgatg ccccgctcgt gggcggtgtc catgatcagg tgggcgtccg
     6901 actcctcggt gtgcgggccg aagttcatgg tgcccaggca gaggcgggag acggtcaggc
     6961 cggtgcggcc gaggtgggtg aactccatgc cgcccaccat cggccgcacc ggcgccgctg
     7021 tccagcacat tccgcagagc gggccgaagc cggaccgaag atcgcccgaa acggccgtcg
     7081 cgcggcggga atgcgccggg agcacgccgg aagtcggcgc gaaggcaccc ggaggcggcg
     7141 cctcaccgac cgtgcgtggc gaacttccgc acggcgagcg gtccgcacac cgccagcagc
     7201 gccgcgcacc agagcagtgt cgcgggcacg gcgtgctgca tcggccaggc cccgccgggc
     7261 gccgacgggt tgccgaacag ttcacggcag gcctgcaccg cggcgctgac cgggttccag
     7321 tccgcgacca ccctgagcca gccgggcatg cccccggtgg gcacgtacgc gttggtgacc
     7381 atcgccaacg ggaagaccgc gaccgcgagt tggccggccg cctcctcctt gccgacggcc
     7441 agcccgagga aggtgccgac ccaggtcatc acgaagcgga gcagcagcaa caggccgaac
     7501 gcctctgcgg cgtccgcggt tccgccccgg atccgccagc cggccgccag gccgacgacg
     7561 gccagcagcg ccagcaccac gatgctgacc aggaagtcgg cgagggtctg gccgagcagc
     7621 aggccggtgc gcgagaccgg catcgagcgg agccggtcgg tgaccccgcg cccgacgtcg
     7681 cgggcggcgc cgaccatggt gggcatgacg ccgttgacgg ccaccatggc gaacagcccg
     7741 ggcatcagga actcgcggta gttcccgccg cccggcacct gcatggcgct gccgaagacg
     7801 tacccgaaga ccaccaccat gatcaccggc acacccagcg aggcggccag cagaccgggc
     7861 gagtggcggt agttgagcag gatccggagc atcgaggacc aggtgtcgga gaccagtcgg
     7921 cccggcacgg agatcatccg acccggcacg gggtgcacgg gcggagcagc ggacacggcc
     7981 atcaggcggc cctccccagg gagttggagt cggcggtgag cgcgagaaag acgtcgtcca
     8041 gcgacggcgg ccgcaggccg acgtcctggg cgaccacccc cgccgcgtcc aactcccgga
     8101 ccaggcgcgg cagcagcacc tccaccccgg gccgggtcac aacggcgacg gtccgctggt
     8161 cgtggtcgac cacgacgtcc ccgctctccg ccagtgcggc cagtaccact gcggcacggc
     8221 cgagttgacc gacctcggcg agggttacct cgatccgggt gccgatcgcg gccttgagcc
     8281 gccatggcgg gccggtcgcg atggcggcgc cgtggtcgat caccacgatg tcgtcggcga
     8341 gccggtcggc ctcctccagg tactgggtgg tgagcagcac ggtggtgccg ccctcggcca
     8401 gctccttgac ggtggaccag atctcctgcc ggctgcgtgg gtcgaggccg gtggtcggct
     8461 cgtccaggaa gagcaccggc gggctggtga ccaggctggc gacgaggtcg aggcggcggc
     8521 gcatgccgcc ggagtaggtg cggacgaggc ggccgccggc ctcggcgagg ccgaagcgtt
     8581 cgagcagctc gccggcgcgg gcccgggcgg cccgggcgcc gaggtggtgc agccggccga
     8641 gcaggtccag gttctcgcgg ccggtgatgc cttcgtccac ggccgcgtgc tgcccggcca
     8701 gcccgacgct gcgccggacc gcctcggcct cccgcaccac gtcgtagccg gcgacgcggg
     8761 ccgtgccgcg gtcgggggcg accagggtgg cgaggacgcg gacggcggtc gtcttgccgg
     8821 cgccgttggg gccgagcagg ccgcagaccg tgccggcggg gacggtgagg tcgaggccgc
     8881 gcagggcctc ggtggctccg gagcgggctc cgaatcgttt cgccacgccc gtcatctcga
     8941 cggccggccg actggtcttc gacatggctc tgcccttcag ctaggtacag cgtacgtaga
     9001 agcgcgcgcc cacgcatcgt actacgtacg ccgtacgtat ctaagatggg taaccgaggt
     9061 gatcttccgt gccgtccagc aagccccccg ccgactctcc gccggcgccc cccgaaccgc
     9121 ccgaggcccc cgaactgatc tggctgcgcc ccgaacgcac cggccgcggc cccaaacccg
     9181 cccacagccg ggcctccatc gccgccgcgg ccatcgcgat cgcggacgcc gaggggctgg
     9241 acgcggtctc catgcgccgg gtcgcggcgg cactcggagc ggggacgatg tcgctctaca
     9301 actacgtgcc gaagaaggag cacctgctgg acctgatgct cgacgcagtc gccgacgagt
     9361 acgactacga cgacctcgcc ccggccggtg actgccgcgc ggacctgctc cggctcggcc
     9421 acgcgcaact cgccctcatg cggcgccacc cctggctgcc cgccctgctg atcgcccgcc
     9481 ccggcatcgg cccgaacgcc ctgcgctaca ccgaccactt cctcgccgtc accgaaccga
     9541 gcggcctcga cggcggcacg cgcatggaag cgatggccct gttcaacggc ttcgtctgcc
     9601 agtacgccca gtacgagcgg accggcgcgg cgggtgccaa gtggcaggcc gagctggtcg
     9661 gttacctcac cagggccgcc atgagcggcg agtaccccca cctgtcggcg gccttcgcca
     9721 ccgcgggccc gccggccgac ccggacacgg cgttcgaccg gtcactgcac cgggtgatca
     9781 cggccgcact gacccccgtg gagcgcggct gaccgagcag tcccacgccg gaacggccgc
     9841 aggtcacagg ccggggcggg ggtgggggcc gcaggccgga ctacggtgac gggctacggg
     9901 ctacggacgg ctgtccaccg aggcggccgt ccgccggagc tccgtagggc cgtacgccgg
     9961 ggctacgggc gggcgggacg ccggctgccc gggaccagca gccagaggag ccagacgccc
    10021 gtgcccagga gcagcatgtt gagcgccatc tgccccggct cctcgccgaa gcccaactgg
    10081 cccgtgccca gccactgcgc gacgacggcc ttggtcacga agaacaggcc caggtccgcc
    10141 gtcacggtga ccgcccagac cacggccgga tgccagcggg gccggggcac ggcgtgcacg
    10201 agggagagca cggcggtcac gaggagggcg tgggggacga acctgtcggg gatggtgccc
    10261 aggtagttcc acggcagggc gctaccgatc gcccagatca gccccatgca gccgatgaac
    10321 cgcaccagga tcgccccggc cgcgctcggg gccgccggcg cggagggcgc agtggccccg
    10381 gaggatgcag aggtcccgga ggacgcgggc gggaggagcg gcggcgtcgg ggcggcctgc
    10441 ccggcctgcg gtggcagcca cgccccggcg gaccccggct ggggcgctcc gggcggcggc
    10501 tgcggggccg tcaacggctg cggcggcccg taccacccac cgccccccgc cacatcggga
    10561 gccgtcggcg tcgcgaccgg cccgaccggc gcgaccggca cggccgcccg cgccaccgcc
    10621 tccagagccg ccaacgtctg ctccgccgag ggtcgttgcg ccgggtcctt ggccagcagc
    10681 gcgcccagca gcggcgtcag cgcgcccgcc ctgaccggcc ggcgcggctc cttcgtcacg
    10741 acggccacgc acagcgcgcc gaaggtgtcc ccgctgaacg gcatctcgcc ctcgaccgcc
    10801 gcgtacagcg tcgccccgag cgaccacagg tcgttggcgg gcgccgcggg cttcccctcc
    10861 agctgttcgg gggccatgta ggcgggcgtg ccgatgaccg cgccggtgcg ggtgagggcg
    10921 gtggtggcgt cggccatgtg ggcgatgccg aagtcggtga ggatcacccg gtcacccatc
    10981 aacaggacgt tgtccggctt gagatcgcga tggacgatgc ccgccgcgtg ggcctgctgg
    11041 agcgccttga ccatcgccac gccgatctcg gcgacccgcg ccgccggcag cgcaccgtcg
    11101 cgggcgatgg cggcggccag cgagagcccg ctgacgtact ccatcacgat gaccggcgca
    11161 ccctcgtgct cgacgacgtc gtgcacggtg atgatcccgg ggtggttcag ccgcgccgcg
    11221 gcccgggcct cgcgcaggac gcgctggacg agctgctcgc gttcggcctc cgtgacgccc
    11281 tgggggagca ggacctcctt caccgcgacg tcgcggccca gggtggtgtc caacccgcgc
    11341 cagacccgtc ccatgccgcc ctgaccgatc agctcctgga gctggtaccg gcccccgatc
    11401 agtgccccgt tcacccctgt cacgtggctc accctagcgg cacggcaccg cggcgttggc
    11461 ggcacgtcgt caaatcgttt ccgctcgggg cccgtcagcc cgtacggtgg cccagccgac
    11521 gatcttggac gccggcggcg taccggcgac cacacaccga gaccgggcgc gtacccggcg
    11581 agttgcgcgt acgccgacga ccgggcgcgt tcccgacggc cggcctcgca cccggatgaa
    11641 caggacggac accatgcagc agtaccaggg ccacgccgac gagggcttcg gcgcggtcgc
    11701 cgacgcgttc gcgcgcaact atgcggactt ccccgaactc ggctccgccg tcacggtctt
    11761 cgccggcggc cggaaggtgg tcgagctgtg gggcggcgtc gcggacgaac gcaccgggcg
    11821 gccgtgggag gccggcaccg tcgtccccgt gttctcgtgc gccaagggcc tcgtcgccgt
    11881 ctgtgcccac ctcctcgccc agcagggccg cctcgacctc gacgccccgg tgagccggta
    11941 ctggcccgag ttcgcgcagc acggcaagga ggacgtcacc tgccggatgg tgctcggcca
    12001 ccgcgccggc atcccggccc tggacgccgt actgggcttc gaggagatcg ccgcctgggc
    12061 gccggtcgtc cgggcgatcg aggagcagaa gccgctctgg gagcccggga ccacctacga
    12121 gtaccacggc catgtgctcg gcttcctggt cggcgaggtg atccgccgga tcaccgggct
    12181 caccccgggg gcgttcttcc ggcaggagat cggcgacccg ctcggcctgg acgcctggat
    12241 cggcctgccc gccgccgaac tccaccgcct ggcacggctg gtggaggccg agggccgtcg
    12301 tccgatgccc ggcccggagc acctgctcac ccggatcgtg acgatgaacg gcgcgctggt
    12361 cttccccggc ctggacgtgc cgcacggctg gaacgacccc gagctgcacg cgatcgagct
    12421 gcccggcgcg ggcgccgtcg cctccgcgag cggcctggcc gggctgtacg ccgccgccgt
    12481 caccggcatc gagggcggtc gggacggagg gcgcgagcga ctcctctccc ccgccatcgt
    12541 gaccgacgtc gtgcgcgaag tctcctccgg cgcagggttc ctgggcttcg acatgggtgc
    12601 ccgctggggc tcgggcgtgc tgctggagtc gccggccttc cgcccgatgc tcggcgcccg
    12661 cagcttcggc aacgatggcg ccggcggcca gttcgccttc ggtgacgacg agttcggcat
    12721 cggcttcgcg tacgtcgcca accgcatgat cggccacggc gacgcccgcg ccaaccacct
    12781 ggtcgacgcc gtccgcacct gcctcggcgc ctgagcaccg acccgccccg ctctcgccgc
    12841 ccgatcggtc acgcccggca cccccgagac ctgtcgggcg gtgccggccg tgccgcgtca
    12901 ctcagaacac gtactcccac cagccgaaca ccgtcaccag cgccttcttc gccgcacacc
    12961 ccaaccggtg tccggccacg gcgaagtaca ccgcgcacgc caccagcaac ccggccgtga
    13021 tacccggcac cgccgaaccc tgcacgacgc cgacgaaggc gaagaggatc cccgacagca
    13081 cggccatgaa cccgaaaccc cagagggcga acctcagcac agccccccac gtcaccgtcg
    13141 ccaccgcgcc gtcctccggc tcggtccgga cgatcagatg ccgactggtg tcgcagagtt
    13201 ccctctccac cacgatcgcc tcccgcggtc ccttccagcg ctccggtccc actgtccacg
    13261 agccggcccg gaccagcatg ctccgccccc tccccgctcg gcaattgacc cacgaaacaa
    13321 ccccacaagt gcaccaatca gcgggccacc cacgcgccta ggctcgttcc catgacaacc
    13381 gttcagatcc cgcagcgcat gaacttctcc gtcaccgcac ccaaggtgtt ccgcgccgtc
    13441 ctcgccctgg acgccgccgc ccgcgagggc ctggacccgg tcctggtcga actggtgcag
    13501 atccgcgcct cccagatcaa ccgctgcgcc tactgcctcg actaccacac caccgacgcc
    13561 cggaaggcgg gcgagaccga ggaccgcgtc caccagctct ccgcctggga ggagtcgagc
    13621 ctctacaccg ccaaggagcg cgcggccctc gcgttgaccg aggccgtgac cgtgctgccg
    13681 cagggcgtcc cggacgcggt gtacgcgcag gcggcggagc acttcgagga gaaggagctg
    13741 gcccagctca tcgcgctgat cttcacggtc aacacctgga accggatgaa cgtctccacc
    13801 cgcaagacgc cgggcacggc gtgaccggac cggccccggg agggcggtga ccgcacccgg
    13861 cggccaccgc cctccgccgt tcggactccg atcccggacc ggaagcccca actgcccgat
    13921 cgggcaagcc cggccgcccc ctccggcact cggcaccgtt gtcgttgaca ctcaaagttg
    13981 gtctagtcca ccgtagggga aagcgaggcc accggggcga gacggcgacc gcgatccctc
    14041 gccggggccg actcaacccg ccggtccgga agacaagttg cccctcgtgc ccgcgcggcc
    14101 gtccaccggc cgccccctcc ggcacgcccc cgggccggcg aacgcacgtc ctgacgacga
    14161 ccgaacggag aaccggcatg agcagaatct gtctggccct gcccaccaac cgggcctgtg
    14221 ccgccacgat ttcggcggtc ggagaggagg cggcgtacgc ggccgagcag ttcggcgtcg
    14281 aggtccacct ggcgctgtcc ggcagcccgg agcagccgat cgtcctgccg gccaagacca
    14341 cgtcgttccg cgactgggcc cgccacctcc acgaccacgc ccagaccgag gagatcggcg
    14401 cgcagacgga gcactggctg gagacgctcc gcgcgggcga ggagtcgggc gtgctgctcg
    14461 acctgctgcc ggacgacgac gagacgctcg agtccgtcaa cacgcgcgcc agtgcctgct
    14521 cggtcaccgt cgcactggag gccgagcaga ccaagctgct gctccaggaa gcgccgtcgg
    14581 cgtaccaggc acggatcgag gagctcctgc tcacggccac cggcctggct ctgaccgacg
    14641 ccctggggga acggcaggtg ctggtcgagc tggagggaca cggccgcgag gacctcggcc
    14701 cgcagctcga cctctcccgc acggtcggtt ggttcaccag cgcctacccg gtcctgctgg
    14761 acatcgcccc gggagcatcg gtcgccggag ccctgcgcca ggtgcgtgag cagcgccggc
    14821 gggtccccgg ggacgggctg ggctacggcc tgctgcgcca cctgcgcacc ggcgatccgt
    14881 tggccgcgga gctggccgag ctgccggcgg cggcggtctg cttcaactac ctcgggcagt
    14941 tggaccagag cttccagccg ggcggactgt gggaaccggc atcggagaac cccgggcccg
    15001 gcctggacgc gcgggccacg cgctcccacc tgatcgaggt caacgccctg gtactggggg
    15061 aggagctgag gttcacctgg acctacagcg accgcctgta ccgcgaagag acgatcgccg
    15121 ggctcgcgga acactgcctg ggcaccctgc gagcgctgat cgccggccgg cccgccgccg
    15181 gggacggcaa ccggggcgcc gactccggct ccgtccccgg cccgcgcgaa ctgagcgagc
    15241 tgctggggcg gttcgatgcc tgatcagccc accccggcgg gtggccggga atcccgcacg
    15301 acggagaccg agaagacgag agacatgtcc gacgccatga ccatcgaaag tgtccacccg
    15361 ctcgcgccca tgcaggaggg catgtggttc cacgccctgt acacgcctga ggacgacgtg
    15421 tacgtggaac aggtcacctg cctgatcgag gggtcgttgg acgcggcggc cttccgccgc
    15481 gcctgggacg aggtcgtggc ccggcacacc gcgctgcgca cgtcgttcca cgcggtggac
    15541 gggaaggcgc cggtccaggc ggtccaccgc gccgtcgagg tgccgtggac ccgggaggac
    15601 tggcgggacg tgccggccga ggagcggcag gaccggctgg acgccttcct gcgggaggac
    15661 cgggcgcgtg gcttcgaccc ggcccgtcct ccgctggtgc ggttcgcgct gctgcggctg
    15721 gacgacgcgg cacatcagtt cgtgtggacc caccaccacc tgctgctcga cggctggtcg
    15781 gtgccactgg tgctgcagga ggtggcggcg tgctacgcgg ccgcccggga cggccgaccg
    15841 gccgcgctgc ccgtgccacg cccctaccag gagtacgtcg gctggctgga gcgccaggac
    15901 gaggcagcgg ccgaggactt ctggcggacc gggctgaggg ggttccacga gccgaccccc
    15961 ctcccgctcg accgcggccc gggcgaggcc gacacacctc cggagcaccg cgtgcgccgg
    16021 accgggcttc cccggtcggt gaccgcggag ctgcagacga tggcccggcg gtacgggatc
    16081 accccgaaca cggtcgtcca gggcgcgtgg gcgctgctgc tgagccggta cagcggcggg
    16141 caggacgtgc tccacggcat gaccgtggcc ggccgtccgg ccgacctgcc cggggtcgag
    16201 gacatggtcg gcctgttcat caacacggtt ccggtccgga tccaggtcca gccgcacctg
    16261 ccggcgggcg actggctgcg cggtctacag gccgggctgc tggatctgcg cagccacgag
    16321 cacacaccgc tggcccgggt gcagagctgg gccgacgtgg ggtccggcgt cccgctcttc
    16381 gagagtctgg tggtcttcga gaactacccg gtggcgccct ccgaggcgca ggaggctttc
    16441 gccggtctga cgataagtca gaacgagacg gaggaacgca ccaactttcc ggtgacgctg
    16501 gtggcggtgc cgggctccgc actcggcctg caactgatct tcgatcacca ccggctcgca
    16561 ccccaggacg ccaccaccct cctgtannnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18121 nnnnnncacc tccccgacca catgatcccc accacctaca ccctcctcga caccctcccc
    18181 ctcaccccca acggcaagac cgactaccgc gccctcccca caccagaacc cgccgcggag
    18241 agcctcggca cgtcgtaccg cgctccgcgg agcgccgtcg aggcggtgct cgccgccgtc
    18301 tggcaggacg ttctcggggt ggaccggatc ggcgtcgacg acgacttctt cgccctcggc
    18361 ggccactcac tgctggccgc gcgagtgcac aaccgcctgc gggcggtctt cggtgtggag
    18421 gtgccgctga ggctgctgtt cagtgagccg accgtggccc ggctggccgc ggccgtcgag
    18481 gcggtccgcc gcgcccagac cggggcggcg gccgaggccc tgccgccgct gctgccgggg
    18541 gaccgcgccg agcccgcccc gctctcgttc gcccagcgcc ggctctggtt ccttgagggc
    18601 tgggagcccg gcacctcgct gtatcacatc accgccgcgg tgcggctgag gggccccttc
    18661 gacgtggccg cgttccggac cgcctggcag cggctgatcg accggcacga cgtgatgcgc
    18721 gctcatgtcg atgacggcga tcccggcgag ccgcgccagg tggtgcggtc cggctgtccg
    18781 gccgcggtgc cgctggtcga tctgagcgcc gtgcccgagg gggaccgggg gagtgccgtc
    18841 acccggctgg tcaacgaggt caccgaccgg ccgttcgaac tgaccaccgg tccgttgtgg
    18901 cgagtggcgc tgctgcgcct gggccccgcc gagcacgtgc tggcgatcgg cctgcaccac
    18961 ctgatcgccg acgggcactc gctggaagtg ctgctggccg agctgggcgc gcagtacgag
    19021 gctgccgaag ccggtcggaa gctcgaactg ccggcgcttc cggtgcagtt cgccgactac
    19081 gcgcgctggc agcgtgggtg gctcgaaggt gaccggctct ccgaagaact cggctactgg
    19141 aaaaagcagt tgggcggact cccggcgatc acactgccca ctgaccgggc tcgcgaggct
    19201 gcgcggggcg tcggggcggc catcgagagc gtccagctgt cggcatcggc cgacgcgagg
    19261 ctccaggcga tcagccggga ggcgggcgtc accccgttca tggcgctgct cgcggtgttc
    19321 gccgtggcac tgggccagaa ccgcgacctg gacgaggtcg tggtcggtac gccgatcgtg
    19381 ggccggagcc gtgcggagtt ggagggcctg atcggcttct tcgccaacac gctcgtgctc
    19441 cggctggacc tggcgggcga ccccaccttc cgcgaactcc tcggccgggc ccgcgaggtc
    19501 tgtctggacg cctacgcgca ccaggacgtg cccttcgagc gggtggtgca ggaactgcgc
    19561 ccggagcgca gcgacagcca tctgccgctc ttccaaacct ggttcgtggt gcaggaggcc
    19621 ccggcggtgg ccgaggcttt cgccggcctg ggggtagagc cggtccgcca cggtgagcag
    19681 caggcccgct acgacctgcg cctggacgtc cagcgcatcg gtgacacgct gcgtgccgtc
    19741 ttcgagtaca agacggacct gttcgagagt gcgtcggtcg ccaggctcgc ccgccgcttc
    19801 ggtcacctgc tggaggtcgc ggccgtcgaa ccggacgccc ggctgtccgc gctgacccgc
    19861 caggtcggcg aggccgacga ccgggcccgg cgcgaacgcc gcggctccgt cagcctggcc
    19921 agcctgaagc gcctgaagaa cgtccgtcgg gaaatcacgc aagaggcagg cggttccaag
    19981 cctgccgaag gaggaatcgc atgacctcgg ccatcgaggg ctaccggctg tcgacccagc
    20041 agcgccacat ctggggtctg ctcgcggcgg gacgcccgga gagctacgcg gcctggtgcg
    20101 ccgtccgggt gcaggagccc tgcgaccccc gacagctgcg cgccgccctg gagcggctgg
    20161 cggcgcgcca cgagatcctg cggaccgtgt tccgccgtcc ggcgggtgtc gaggtgccgc
    20221 ttcaggtcat ctccgacgac cggaccgagg tcggcttcga gacccacgac ctgcgcgaac
    20281 tgcccgccga cgagcagcgg aagcggtacg ccgaactgcg cgaggcgtgg cctgccaggc
    20341 ccgtcgacct ggagcacggc ccggcgctgt cggccgccct ggtgctgatg accggcaagc
    20401 cgggcgacac ggcgcaactg ctgctgcggt tgccggccgt ctgcgcggac gaggcctcgt
    20461 tgcgcgttct ggtgggcgag ctcgcccagg acggcgagcc ggacgacgag ccggacgacg
    20521 ggccgctcca gtacgccgac ttcgcccagt ggcagaacga ccttctcacc gccgaggaat
    20581 tcgggctgga gcgcgagtac tggctcggcc aggacccggc cgggctggtc gggccggagc
    20641 tgccgttctc cgggcacagt gccgagaagg cgctgtttcg gccggccgtc ctgcgccgac
    20701 agctgcaggc cgagctccgc accggcctgc gcgagctggc ctggcagctc ggtgtggaac
    20761 cgtccaccgt cgtgctggcc gtgtggcgcc tgctgctgga gcggatagcc acggcggcgg
    20821 acttcgccgt cggggtgcgg ttcgacaacc ggggggccga ggaactgcgg tcggccgtcg
    20881 gtgcgttcgt caagtacctg ccctccagta cgcggtcggg gtcggacgag tcgctggccg
    20941 gcttcgcccg gcggttgcag gacgagctgg accggatggg cgaggtccag gagtacttcg
    21001 gctgggagca gatcgagtca cggctgccgc agacccgttc gggcgccctg ttcaccgccg
    21061 ccttcgactg gtccgctgtt gaaccggtgc cgcgggcccg gacgttccag ctcgatgagg
    21121 ccgacgcggt gaccgagcgg ttcgaggtca gggtcgccgc ccgcgacgac ggcggttccc
    21181 tgcggctcga cctctggtac gacaccgggg tgctgtcgcc ggtggacgcc cgtctgctgt
    21241 ccggccagct gctcgcggtg ctgcgcgcgg ccgtggcgga cccgggcacc tcgctgcgcg
    21301 cgctggccgt ggtggacgcc gcaccggagg acggcaggcc ggcggaccgg gtgcccgcca
    21361 caggcggccg gggtacggac gcggtccacg tccaggtggc ggagcaggcc cggcggcacc
    21421 cgcagcggga ggcggtccgg gtcctggacc ggacgctcag ctacgcggag ctcgacgaag
    21481 gggccaaccg gctggcgcac cacctgcgga gcctcggggc cgacgcggat cgcccgatcg
    21541 ggctctgcct ggaccgctcg gtcgatttcg tggtcggcct gctggggatc atgaaggccg
    21601 gtggtgccta tctgccgctg gatcccgccc tgccggcggc gcgccgttcc gagttgctgg
    21661 gccggcgccc ggatcgtggt cacctcggcg gagcacgccg ggccggctgc gccggaccgg
    21721 gtcgtggtcc ggctggacgc cgaccatgcg ctgatcgctg cgcacagtgc cgaggagccc
    21781 gccggccggg tctccgacga ccagctcgcg tatgcgatct tcacgtcggg ttctaccggg
    21841 gtgccgaagg cggtgggggt gtcccatggc agtttggcgg ggtatgtggc gggggttggt
    21901 gcgcggttgg ggttgccggg tggttcgcgg tatgcggtgg tgtcgacgct tgcggcggat
    21961 ttgggtcata cggtggtgtt cccggcgttg tgttcggggg ggacgttgca tgtggtgccg
    22021 ttggatgtgg cggttgatcc ggtggcgttg gcgggttatt tcgggcggtt cccggtggat
    22081 tgtctgaagg tgacgccgtc gcatttgcgg gcgttgttgg acgggggtgg ggcggcgggg
    22141 gtgttgccgt cgggtgtgtt ggtgctgggt ggtgaggtgt cggactggga gttggtgggg
    22201 cgggtcgggg ggttggtgcc gtcgtgtcgg gtggtgaatc actatgggcc gacggagacg
    22261 acggtggggg cgttgtcgtt cgaggtgggg ggttcggtcg ggggtgcggg ttcggtgccg
    22321 atcgggtcgg cgttgggttc ggcgcgggtg tatgtgttgg acgagtggtt gcgtccggtg
    22381 ccggtgtggg cgtcgggtga ggtgtttgtc gggggtgggg gtgtggctcg ggggtatttg
    22441 ggtcgggcgg ggttgacggc ggagcgtttt gtggcggatc cgtttggtgg gccgggtgcg
    22501 cggatgtatc ggacggggga tcgggcgcgt cggttggctg atggttcgct ggtgttcttg
    22561 gggcgtgtgg atgatcaggt gaaggtgcgg gggttccggg tggagcctgg tgaggtggag
    22621 ggggttctgc gtcgttgtgc gggggtgcgc gaggtggtgg tggtggctcg tgcggatggt
    22681 gcgggtgtgg tgcggttggt ggcgttcggg gtgtggggtg cgggtgtggg ggagggggag
    22741 ttgagggcgc attgtgcggg gttgttgccg gagtacatgg tgccgtcggt gttcgtgggg
    22801 ttggagcggt tgccgttgac gggcaatggc aaggtggacc ggcgggcttt gccggaggtg
    22861 gtgttcgggg gggcgtcggc ggtgttcgag gctgcgcggg ggccggtgga ggtggctctg
    22921 gccggggtgt gggccggggt gctgggggtg gagcgggttg gccgggatga tgatttcttt
    22981 gcgttgggcg gggattcgat cctgagtatt caggtggtgg cgcgggcggc gcgggcgggt
    23041 cttgcgttga ctcccaagct gatgttccgg ttcccgacca tcgccgagct ggcaccgcag
    23101 gtccgggccg cctcaggtgc ggccgtggcg gaccagggcg tggcgagcgg ccccgtgccg
    23161 ctgaccccga tccagcgctg gttcctggag gcggagccgt cctctccgca gcactacaac
    23221 caggcggtgc ttctcggggc cccgaggccg ctggatccgc gggcgctgga ggaggccctg
    23281 cgcgtggtgg tcacccacca cgacgcgctg cggcttcgtc tgctgcgcga cggtgacggc
    23341 ggctggtcgc tggagaacgc gggcctggag gctctggacc gcccgttgtc ggcgaccgtg
    23401 gacctttccg aggtggccga cgcggagcgg cctgcggcga tcgaggcact ggcgacgcgg
    23461 gtgcagacgg ccgtcgatct gaccgcaggc tgcgtgctgc gcgcggtccg gttcaccttc
    23521 ggcggcggcc aggaccgact gcttctggtg gtccaccacc tcgcggtgga cggcgtctcc
    23581 tggcggattc tgctcgacga cctcgccacc gcctacgagc aggcggccgg cggactgccg
    23641 cctgccggcc aagaccaccg ccttccgcac ctgggccgag cgactggagc tctacgcgca
    23701 ctcggaggag ccgctggcgg aactcggcta ctggaaggag gcgttgggcg gagcgggcct
    23761 tgccgtcccg cgcgacgacg ccgggccgtc ggccaacacc cacggcagcg ccgcgacggt
    23821 gaccaccgtg ctcggcgccg aggagaccga ggccctgctg cgcccggccg ccgccggcgt
    23881 gggcacgctg gacacgctgc tgaccgccct gggccggacg atcgcggact ggaccggcga
    23941 gcggcgggtg gtcctggact tggagggcca cggccgtgag tcccactggg acgacgtgga
    24001 cgtctcccgg acggtcggct ggttcaccag tcagtacccg ttcgctctgg acgttccggt
    24061 gggggaggac ccgggggcca cccgccgcag ggtgcacgac cggctcgcga acgtacccgg
    24121 cggcggcctc ggctacgggc tgctgcgcta cgggcggtcg gacgaggcgg tggaggcaat
    24181 acgcgcgctc ccggatccgc aggtccgctt caactacctc ggccaggtca cgaccgccca
    24241 ggacgccgac ggcccgttca ccacggcgtc ggagagcacc ggcccctccg ccgacccggc
    24301 aggtacccgg cgccacctgc tggacgtcac cgcggtcgtg gtgggcgggc ggctgcaggt
    24361 gagctggacc cactgcccgc agacccaccg gcaggcgacg gtccaggccc tgtccgcggc
    24421 cttcctggcg gagctcgacc agctgcgcgc gggggagcgg gcggcggagg cgtccggccc
    24481 gcggccggag gacttcccgc tggcccagct cgaccaggcc cagctcgacg cgatcgcggc
    24541 catgctcggc gaccagggct gaccaggccg acgggccggg ccggcgggac tcgtcggccc
    24601 ggcccgtccc cgggatcagg acggcgcccc cggccgcagc tcaccgctgc gtacccgggc
    24661 gacgtcgcgc atgtactggt accgctccgg gaggatcgcg tggccggccc gcacaccggc
    24721 cgccaacgcg ttcatccgtc gctggtcggt tccggtccaa cgcagcccca gcagctcccg
    24781 cagctccggc gtcagggtgc ccacggtgac cagccgggca agccgcccca gcgtctcacg
    24841 cagcgccggc caggccgggg cgagccgggc gggcaggtcc gggggccgcg gcgggtggcg
    24901 tagggcggtc agcagcgtcc gggcggtggc ggtgttctcc agccggtggg tgaccatgtc
    24961 ccggaagtac ctccggaact cctcgacggt gggcggcatt tcccgctcgg ggacgagcag
    25021 cacccggccg agttggcgcg actccgcgta gagctgccgt tgctgggcga ggtcgagcgg
    25081 gcgcccgaac agccgacggg cggtgacata ccgttcgaag aggctgccgt tgacccaggc
    25141 gtaggccggg ccgttgaggg cgtggtaagc gcgcccctgc tcgtcgacgc cgtggtagga
    25201 gcggtgcagt tcccgcaacc ggcgcccctc ggagagcgcc acgggaccgc cgtagatgta
    25261 cttgagcatc gagttgcccg tgcgcagggc gcgtccccag gcgtcggcgc ggaaggccga
    25321 gtggtcgccg acggccgcgc cgaccatcgg atgggccact tgcaggagga gtgccgacgg
    25381 gacgatcagc agcgaccggt actcaccggc gatgtcccac atcagcgagc cggcgccgag
    25441 cggctccggc ccgggagtgt gccgctgctc ggtgccaccc gtctcctgat ggtccgtcga
    25501 cggcatgtcc gggctctccc gtccgtaggg tttcagggga ttctcacgaa acctgatggc
    25561 aggtcaactt gtctatcacg cggggcttcg gagctgatcc gtcctgtcgg catccggggc
    25621 cgggcgcgcg atgtcccgcg agctcaacta cagtttgtcg cagcacaagg acagtttgtg
    25681 gtgttgcgtg ggcgtcgtcc cccgcgcacc tccggaaggt cacgaggttg gatcatggta
    25741 gaggtcgcgc ccaaggttgt cgtcgtcgtt cccacttaca atgagcggga taacctgccc
    25801 gtcctcgccg gccggctcac cgacctgctg ccgaacctgc atctgctggt ggtggacgac
    25861 aattcgcccg acggtacggg cgaggttgcg gacaagctcg cggcggagtc gccggaccgc
    25921 gtgggcgtgc tgcaccgcac cgagaagaac gggctcgggc gcgcctacat cgccgggatg
    25981 acccgggcgt tggccgaggg ggcggacgtg gtgatccaga tggacgcgga tctctcgcac
    26041 ccggcgtcgg tgatgccggc catggtggag accctgctgg gcacggacgc cgccgtggta
    26101 ctcggctccc gttacgtcgc cgggggctcg acggcggcgg agtggccctg gcaccgcaag
    26161 gcgctgtcgg cgtgggcgaa catctacgtc aacacgctgt tgcgactggg ggtccgggac
    26221 gcgaccgcgg ggttcaaggc ctggcgggcg gagacgctgc gggcgatcga cctgccgtcg
    26281 atccgcagca acgggtactc cttccaggtc gagatgaact tccgcaccgt caggcgcggg
    26341 atgaggatcc ttgaggtgcc gatccggttc caggagcgcg tcgagggcgc ctccaagatg
    26401 agcctggccg tgcagatcga gtcggcgttg acgccgtgga ggctgctcgc gggccccggg
    26461 aggcgctgac accccgcccc ttgacccggg gcccgccgtc ggactcctgc ctgccttcgg
    26521 gtggccgggg gaggccgacg gcgggccctt cgcggtttca tccctcgtga ggccggaccc
    26581 cgcccccgct gtctctgggc gatattcagc cagttgatca aggcgtgacg ccaggtgtgg
    26641 tccgccacct gtgacgtaca tatgacggct gaccagcttg aagcagcgcc actcgagttg
    26701 gccgaaagtc atctactcgc tcattgtgcc gaagttcgag tgtttactcg aatgcgcgtg
    26761 ggtgtaaaca ctgatgcggc ggggcccact acatgtggcg aggccggtcg aggaccattc
    26821 gcgcagctcg ccccagcggc ggcctgttca ggaccacgtc cgccggccgg gccccgaggt
    26881 agcaggacat gcgaaaacgg gggaatcatg gcaaggcaga ccgtcgccgt catcggcgcg
    26941 ggagtatccg gtatgacggc ggctcacatc ctgcagagga gcttcgacgt caccgtcttc
    27001 gaggccaaag cgcggctggg tggaaacgcc gacacccgca tggcgggccc gttcccggcg
    27061 gacctggggt tcgtcggctt caacgagctg gcctacccga acctgatgcg gctcttcgcg
    27121 gagctcggcg tcatgagcaa ggaggccgtg cagtcggccg atctgatctg ccgggactgc
    27181 gagttcgccc acatggacgg cgacaccctg ggtgcggagg ggctgccccg ccggccgcgg
    27241 gacgccagcg acgccacctg gcagaagttc accgaggacc tggtgcgctt cggcaccgag
    27301 ctggccgaac tcgcgggcgg aggcgacgac gagctcaccc tcgggcggct gctgcgcgag
    27361 aggtcctact ccgactactt cacccggcac cacctctacc cgaggatcgg gccgtggttc
    27421 ctgctgcacg cacgggacct cgaccgcatt ccggcccgct tcctcgccgc gaccatgagc
    27481 ccgctcgccc gtcccgaggc ccgcgcggcc tggcgggtgg tcgacggggg gagccggacg
    27541 tacgtcgagc ggatcgccgc cggcctgtcc tccgtccggg tggcgacacc ggtgcggtcg
    27601 gtcagccgcc gcgagggcgg ggtcgaggtg cgcgacggag ccgaccgggt gcaccacttc
    27661 gacaaggccg ttgtcgcggt ccacccggcg caggcactgc ggctgctcga ccggccgacg
    27721 tcggccgaac gagccgtcct cggggccttc gagtacgcga aggtcgagat ggtgctgcac
    27781 accgacagca gcatcctgcc gtccgacaag ctgtcaagcg cactgatgat ggaggtttcc
    27841 tgcgcctctc cgcgcccgtt cttctccgac tgccatgtcg acgtgaccaa gtcgcagcac
    27901 ctcgatacgg atgtccgcta cctgaagacc ttcaacccca ccgacacgat cgacccggag
    27961 aagctggtcg cgtacgagac ctacgaagtc ccggtcttca cccgggagag cgtcgccgcg
    28021 cagcggaggc tgccggagat caccgatgac gtcatcgcat gggccggtgc ctaccacggc
    28081 aacggttttc acgaggcggg ctgccacgcc ggcgtgatgg cggcggaggc cctcggggtg
    28141 tcctggagct gagcccgcgc tccagacggg aatcgcgttc ctgtcgaaag atccagacca
    28201 gcctgaaacg gactaattcg acgtgacaac tctggatgtc ccccccgttc tcgatccgtc
    28261 cggtattcgt tctgcggtcg acgagctcct ccacacattc ctcgacgagc aggacagcac
    28321 tgccaccggt cccgaactcc tcctgttcac ccgaacgttg cgcgacctgc tggatgccgg
    28381 cggcaagcgg ttgaggcccg tcctgtgcgt gaccggatgg caggcggtca gccatgagcc
    28441 tccgccgccg gtggtgatcc gggcggcggc ttcgctggag ctcttccacg tgttcgcgct
    28501 gatacacgac gacatcatgg acaactccgc cacccgccgc ggccgcccca ccgctcaccg
    28561 cgtcctcgcc ggcctgaacc ggcaccatcc gcgagcggag gccctgggtg ccaacgccgc
    28621 aatcctgctc ggcgacctca ccctcgggtg gtcgtacgac ctgctgtacc gggagggctc
    28681 cgcggaggac cgggccgcca tcccctgggc cgtgctcaac gcgatgcgca ccgagaccct
    28741 ggtcggccag tacctcgacc tgcaggccac cggacaccgg gtcccggatg tcgacgccgt
    28801 gtggagggtc atccgctaca agaccgccaa gtacaccttc gagcgtccgc tgcagctcgg
    28861 tgcgatgatc ggcggcgccg acgacggcca gcttcgggcc ctgtccgact acgccctgcc
    28921 ggtcggcgaa gccttccagc tccgggacga cctgctcggt gtcttcggga accccgacca
    28981 caccggcaag ccggccttgg acgacctgcg cgagggcaag cacaccgtcc tggtcaccac
    29041 cgcctacgag ctggcgactc ccgctcaggc cggccgcctg gacgcgcacc tcggtgaccc
    29101 ggagctgagc cacgaggccg ccgaggaggt cagggccgtc ctcgtcgaca cgggcgccgt
    29161 gggcgtgatc gagcagatga tcgccgaccg gcgtcggcga gcggtggaca gcctcgccgc
    29221 ggccccgctg cactcctccg cgagggccgt cctggacagc ctcgcggccg ccgccaccac
    29281 ccgcatcgcc tgagaacaac cgagttcgag gaaccgtgat catgtcgcaa gagctggaaa
    29341 tcaaggcccg ggcagtgccg gggggcatcc cggtgctcgg ccacgtgctc ggcttcgcag
    29401 tctggccgtt gaagttcctc gacgagcagc gggaactcgc cgatatcacc gcgatcaacc
    29461 tcggccccaa gcaggcccgg atcgtcaaca atccgacgct ggtgcgcgag ctcctggtct
    29521 cccgcaccaa ggacttcatc aaggccggtc cgctgtacga catctccagt gccttcgtcg
    29581 gcaacgggct cgccatcagc gagggagcct tccaccgccg gcagcggcgc ctgatgcagc
    29641 cggccttcca gcgctcgcgg atgcccgcgt accactccgg catgcgggag gcggcggagc
    29701 agatgacggc ccgctggcgc agcggccagg ccgtcgacgt gcacaaggac ctcttccagc
    29761 tcgccgtctc ggtcatcggc aacatgctgt acgaggggcg cttcaccgac gagatgacgg
    29821 accggatcgt ctgggccgtg tccaccgcgt ccaaggggat cggatggcgc agcgtcgtcc
    29881 ccgcggcctg gacccacacc ctcccgaccg aggagttccg ccgcttcacc cgcgcccagc
    29941 aggccctgca cggcctcggc gaccatgtgg tggccgagta ccgcgagcgt gacgacacgg
    30001 acccggagca cttcctgtcg atgctcctgg ccgcccggga cgagaacggg gatccgctga
    30061 gcgacaagga actgcgcgac gaggtcgtca cgctcttctc ggccggcagc gcgaccgtcg
    30121 ccacttcgct ggcctgggcg ctgcacctgc tcagcatcca cccggacgtg gaggaacggc
    30181 tcttcacgga ggtcaccgag gtgctggccg gccggccggt caccgtcgcc gacctgcccc
    30241 ggctggagta cctgggccgc gtggtcaccg aggtcctgcg gctctacccg ccggcctggc
    30301 tgctgccgcg catcaccccg gccgacaccg agctcggggg ccatcccatc ccgaagggca
    30361 cctacgtctt cttcagtccc tactcgatcc atcacgacgc gcggctctac ccggaccctg
    30421 agcacttcga cccggaccgc tggctgccgg agcgctcggc atcccggccc cgtgaggcct
    30481 acctgccgtt cggcgccggc atccaccagt gcatcggcaa caacttcgcg ctcaccgagg
    30541 ccaccatcgc cctcgccacc atcgtcgcga agtggcggct gcgccggccg ccgcgggcca
    30601 aggtcggtac ccgcagcgcc gctctgctcg aaccggtcgg gctcaccctg gtcgccaagc
    30661 ggcgggcggg gcgcacgccg gcggtcgccg cgagcgcccc ggcagtcgag tcgcccggct
    30721 gccccgtcac cgccgcccgg ccggcggccg acgcctgagc gccggccccc agaacccccg
    30781 cgcccgcatc ccgggcgggc cgccgtcgaa gtcgttccac cacacatgcc aaggagtacc
    30841 acccatgccc gaagagctga acccctgtcc cgggatcggt caggacaccc gggtccaatt
    30901 cccggtcctt gcccagcgct tcacctgcgg cctccacccc gagtactatg agatcctccg
    30961 ccgtcacgag gcctgggtcc gtgagaagct cctgccgggc aacccggagg cggccgacca
    31021 gatcctgcgc gacaatctga gcgcgatgtt cgtctgcatg tcctactaca atctggacac
    31081 cgaacgtgtg ctggacatct gcaacctgac ggactggctg ttcatccacg acgccgacgt
    31141 cgcccgcctg cggaccacgc cggacagttc ggacgtggcg aggcagtccg cggtggacgg
    31201 ctacatcggc aagctcaggg gcatgctgga gggcggcgcg gctccggacg agccctgggc
    31261 catggacagc atcaacgacc tgatcacccg cttcagcgcc aagtgctcga ccgcgatgtt
    31321 cggccggctg gtggaggcgt tcaactacta cagcctggag acgatccggg acgaggccag
    31381 cgacctgctc agccagaaga tcaccgacct cgacagctac atggagatgc gcgccgccgg
    31441 cgggagctcc gccacgctct tctaccacgt ggtcaccgag tacgtgctcg gcgtcgacct
    31501 ggaccgcgag gtcctcgacg acccgctggt ccagcagtac tggcagagca tcatggacca
    31561 ctggtacctt ccgaacgacc tgctgtcgtt ccgtgccgag tgcgcccgcg gtgatcacaa
    31621 caacgcggtc tgcctgctgc ggcgcttcga aggactgagc ctccaggagg ccgtcgacaa
    31681 ggtggcggca ctgatcgacg accggcagga ccaggccgtg cggcagtacg cggagatctg
    31741 cgcctcgccg ctggccgacc accccggcct gctgcccgtg ctggagacct tccaggccat
    31801 cagcgccgcc aaccagcgct ggtcctacat ggccccccgc taccacggcg agggcttcgt
    31861 ctggaacggc gtcctcagcg gcgaggtccg gctcacgccc gaccacacct acttccccgc
    31921 cgtccccatc accggtgaac cgacccggtg accagtgttt ccgacaccac ttctgtacgc
    31981 tccgaaaggc acctaccgat gaccgaaggc tcgatcgcgt cattcgttcc gaccaaggac
    32041 gacatcgcgg cgttctacga caactcgatc ccgctgatca atcagctggt cggcaacaac
    32101 gtgcacgtgg ggtactggac gtcctcggag gaccggagtt cgctgcagaa ggcgaccgac
    32161 cggatgaccg acatcgtgat cgagcgtctc gccgtcaagc cgggcgcgcg ggtgctcgac
    32221 gtcggctgcg ggctcggtgc cccggcgatc cgcctggcga aggccgccgg cgtccacgtg
    32281 gtcggcatcg cgaccagtcc gaagctcatc gacgaggcgc gcgaggcagc ccagcaggcg
    32341 ggcctggccg accaggtgac cttcgaggtg gtcgacgccg aggagatgga ctaccccgac
    32401 gagtcgttcg acgccgtcat ggcgatcgag tccctcgtgc acatgaacga ccggccgcgc
    32461 gccttcgggc gcatcgcccg ggtgctgcgg ccgggcggcc ggctggtact gaccgaccgg
    32521 gtggagatcg ccacgccgac cgagcagcag cgggaggtcg tcgaggccta ccggaggctc
    32581 tcgatgaaca gccccttcct gaagctggac gagtacatcc ggttcctcat cgaggcccgg
    32641 ctgctcccgg tcgagtacag ggacatcacc cccgagacca tggcacacca gctccacctg
    32701 ctggaggcca tcgagcagga gaccgcgggc tccgccacgt cgctcgaccc ggcagtcctg
    32761 tcggccggca agtccgtctt caccggcctg ttcgaggcgc gcctgcccac caacatgctg
    32821 atagtcgccg agcgcgggtg accaggcgtc ctccagcgcc ggctacggac ggctcccggc
    32881 ccgcacgggc cgggagcacg tcccccggcg ccgtctaccg ggggatggac caggccacgc
    32941 tggaccggca gtactcgccg agctcccgcg tgccgagcct gcaggcctat ctcgacgagt
    33001 acgcgcagct gagcgagacc gcgcgccggt cccacccggt ccacaccgcc ctggcgtacg
    33061 gacctcaccc cgcggagacg ctggactact tcccggccgt ggccggccgc cccggcgggc
    33121 gccgggaacc gccgccgttg caggtgttcg tccacggcgg gaactggcag gcgctgagcc
    33181 ggtcggaatc ggcatttccc ggtccggcgc tcctccgggc cggcgcagcg ttcgccgtcg
    33241 tcaactatgg cctggcgccg gccacccggt tggacgacat ggtcggcatg gtgcgccgca
    33301 gcatcgggtg gctggtgcgg aacgcggatg agctcgggtt cgccgcggac cggctccatg
    33361 tcagcgggca ttcggcgggc gcccacctga tagcgatggc gttgttaccc gactcctccg
    33421 acggtccctt cgaaggaccg gacgtctccg gccggatcgc cggcgccgcc ttgctgagcg
    33481 ggatgtacga cctggaaccg gtacggctgt cctacgtcaa cgacgcgctg agtctggacg
    33541 aggccggagc gcaccgcaac agcccgctgc accggctacc gtcacggctg ccgccgctga
    33601 tcatcgcccg tggcggcaac gagaccgagg agtacgcctg ccagcaggac cggatggcgc
    33661 aggccctgcg cccacgcacc tcgctcaccg agatcgtcgc cgccgcgcgg gaccacttca
    33721 gcatcccgta cgatctcggc gccggcggca ccgcgctcgg ggacgccgtc ctcgcccaga
    33781 tgggactggg agggacgacg gcgtgacgtc ggggctgccg ctccgggcga gccgggcaac
    33841 gcccgaccgg acaccacgct gtcggcgaac ggtatgagcg ggttgtgact tcgcccccgc
    33901 cggatgtgat ccggcggggg cgaatgccgt cgaggtcttc caccggtccg gccggtgatg
    33961 tcgggctact tgccgaaccg ccgctcgcga ccggcgtacg agcgcagcgc gcgaagaaag
    34021 tcgacgcggc ggaacgccgg ccagtagcag tccacccagt gcatctcggc gtaggccgac
    34081 tgccagagca gaaatccgga aaggcgctgc tcgccggagg tgcggatgat gaagtcggtg
    34141 cggtcggcgg tcggcgagta caggtgccgg gagatgtcct cgacgtcgaa ccgctcgatc
    34201 aggtcgaccg ggtcgccgcc ggccgcgatg tgctgctcga aggcgctctt gacggcgtcg
    34261 acgatctccc ggcggccgcc gtagccgacc gcgacgtcca ccttgagccg accgcgcccg
    34321 gcggtcgccg cggcggcctc cttgagcacc cgggcgctgt cgccgggcag caggtcgagc
    34381 gagccgatca cctggacctc ccaggggcag tcctcggccg cgatgttcct gacggtttcc
    34441 tcgatgatct cgatcagcgg cccgagctgc tccgcgggcc gcccgaggtt gtcgtcggag
    34501 agcatgaaga gggtgacgtg ctcgattccg gcggccgtgc accagccgag gaactcggcg
    34561 gccttggcgc caccggcgcg gtacccctcc cggacgtcct cgtgccccgc ctgccgggcc
    34621 cagcggcggt tgccgtcgag catgatcccg acgtgtttcg ggcggggcag gccctccagg
    34681 gtgctggcca gccgacgctc gtacaccgcc tccatctgcc ggcggaggaa cagcgggagc
    34741 agcttcatga accctctcca acgggtcgta cgtatctcca gcagacggta tcaacgcccg
    34801 tggggcccct ccgccacagc ttgtaacaat cctgctacag agaccacttg accgggcggc
    34861 gaaaggcgat tcgacgcgtc ccggcgggac gtccggctgc tcggggccgt tcgtcagccg
    34921 cgggaccact ccgccggtga ggcaccgggg agaattcgga ggcggtccgg aacgtgggcg
    34981 tcggcgaggg cggtgccgag tacgacggtg tcccacgcgt cccacgggat tccggcgtcc
    35041 tccatcgccg tgacgaagtc gcgccagtcg cgtcggccgg actcgacgtc ggcgaggagt
    35101 ccgcgcagcc gtgcgtcctc gtccgcgtgg accacgccgt cccgcccggc ggatccgatg
    35161 gcctccagcc agcgggatcg gcggctcacg aggtcgaggg caggctcgcc cggtgtctgc
    35221 gcgtagagcc gctcggcctt ggcccggggg gattcctccg agccggtccg gatggcctgg
    35281 atgacccgtc gccgctgtcg ttcatcgagg aggacggaga gctcgcgaac gacgtcggcc
    35341 ggttcgtccg gcgagtgcac gccgttgagg atgtagttcg tggtggtcag cgaggaccgc
    35401 agctggtgcg gcgcgcggtc cgtggcattg gccgacccct tgagtcccgc catcctcact
    35461 gaggccggca gtgcgcccgc gggcatccgc accaccagca gcagcatggg cgtccgctcc
    35521 atgaacagct ccgtgacatc gcggcggtca cgggtggcga tgttccactg gaactcccac
    35581 aacgcgcgga tgacatgccg gccgccgctg gtgatctccg ccgcgacgac cctggcgtcg
    35641 tgccgcgcca gccattcgaa gactgtttcc agctcgcggc cgaccacggc gtccggcttg
    35701 cacaggagca ccgtgtggcg gtccagccat ccacggacca cctcggccgg cccggccgcg
    35761 gcgaggtcct cccatccttc acggaagtac agatcgaggc cgtagaacct ccgcttcatc
    35821 ggttggaccg atagccaggc cggaatctcg tcgccgagtc gaccggtgcc gaagtcgatg
    35881 gggaccatga cgggtgttgc ctccgaagtt cttccgaaat gcctgccgcg ggcgggggga
    35941 cgggtcagcg cgcccggacg cggaggtcga agcgggacac gggccgggcc ccttggacga
    36001 catcgatggt gaggggcgtt cccaggtacg tcttggcggg atcgtcctcg gtgccgaccc
    36061 gcgcccgcag ttcggtcggc aggtcgaact ccgcgaccga ggtgtagctc gtggcgcagg
    36121 cagtcatctc cagctctgcg gccggagtgc cggtgcgccg ggagatggtg gcgagtgcca
    36181 gctgtcgtgc cgcctccaac tgcaccatgc cgaagatgtg gtcgatcggg tggtcgaaga
    36241 ggaccggatg gcggatgtcg gcccgcacgg tggctgtgga cacgtcgtcg gccagggcga
    36301 gatctgccag gacgatgttc tcggggttca cccgccccac ttcctgcggg ctcaccgtcg
    36361 tcgtgggcgg ctccggaaac accagctgga tcggcagctc gcggcccttg cgcatgaagt
    36421 tgcgcatttc ccgccacgtg gtccgtttga tccacgtcat gcggatgcgg acgtcggcga
    36481 ccttcgcccc gtccacccgg atcacgaagt tccacagcag gcccgacagc acgcgcccgc
    36541 gcctccactc gcgctcgacc gtgctctcca ggaccgcgtt caccggtcgt gtggtgtcca
    36601 gcggcttctc gtcggccagc cgggcgtcga gctcctggaa caggaactgg tagtcgttgc
    36661 cctccacggg gatgccgaac tggctgtgtg ccacgacgaa gcacgcctgt cggcacacct
    36721 cgacgagcag cgcgaggtcg ggctggtggt tctgcagcgg gtactcgcag tagaagctgt
    36781 gcgcgcgggg cagctgtacg cccatcagca tttcgcgatc tgacgtgacc gagaaatcag
    36841 tgatgaagac ctcgtcgatc gaccacttgt gcaccagctc cctcggtatg gtctgccggt
    36901 gtgcgatcgc ctgtactccc atgggaaatc ctttcctgat gccgacgtgc gaaggacctg
    36961 ctactgaagg tcggagagga ccgcggcccg ggcggacggg tccatcatgt cgacgttcga
    37021 gacgtagcac cgggcgttct cgcagagacc ggcaagcgtc ttctgcatgg tgttgtagtg
    37081 ctttgcgtag cgctggacgt cgtaaccgaa atgtgcgatc agatcgtcct tcaacccgta
    37141 cgtggtcacg ccgaggccga actggtccag gaaggggagt gccgttcccg gatccacctg
    37201 gtgaaatccg gccggagtgt cctggcgtga gttgacgatc acgatgttgc ggaccggggc
    37261 ggaattcgtc gctggtttcc cgaagaggat ctccggactg gagatgtact cgccctcctc
    37321 gatgtgccgg ggcagccggt gtcggtcgat gagctctccg aaacacgcgt cccgccggac
    37381 ccgcatggcc gacgggacac cgtgtgccgt gaccccccgc accagcatgt gggtgttgga
    37441 gaggaactgt gcgccgccca ggcaggcctg ggcgaggaag acgctcttcc cgccgccggt
    37501 ctgcccgaac aggagtgtgc cgtcgccgtt aagggtgaac ccggctgcct tgaggtccag
    37561 caggccgttc tcggcggcgt ggacactcag gatgtgcttg atgaagtacg gccagaccag
    37621 cttctccagc gagcgcccgt agacgtggaa cgtccggcca cgggtgacga ggtagaccgg
    37681 gtcaccgaaa taggggccgc ggtagtagcc cttggtgaag cgcttggccc gcacggtgga
    37741 gtccaccagg tgccggacgg cctcgacgtc caccttgtcg cggtcgaggt cgtaacagcg
    37801 gatctcgaag tcggccgcgg catcgtcggc cgcgaaacgc gtgaagtacg accgcgcggg
    37861 agggctctcc agattgctgc acagccggat gcggatcagg ttgaggtcga cgacggacgt
    37921 cgacctgatt gccgggccgg gcggcggccc tgcggccggt gggcccgtga agggggcagt
    37981 catcactgtg ttcgctcaga tcgtgagggt gacgttgtat tcggtcagcc accggttgag
    38041 ccagaccgcg agttccaggc ttccccggtc gtaggagcgg ctgaccacgc cctgcggccg
    38101 atcgagcgcc gtccgggcct tcccggcgtc gagcaggagg tggacgggcg cactccggtc
    38161 ggcgaggatc gccgccgtct ccttgcgcag gccccgctca tagccggggt cctgggtggt
    38221 cgggtagggc gtcttgttcc gttcgacgat cgaggccggc agcaggtcgg cggtggcggc
    38281 gcggagcagg ctcttttccc ggccgtcgaa cgacttcatg ctccacggca cgttcgcgac
    38341 gtactcgacg aggcggtgat cacagaacgg cacgcgcacc tccaggccga ccgccatgct
    38401 catccggtcc ttccggtcga gcagggtctg gacgaagcga gtgaggttga gatacgtgat
    38461 ctcccgcatc cggcgctcca ggccgtcctc accgggaaga gcgggtacct cgtcgagtgc
    38521 ctcgcgataa cgggcctcgc ggtagccggg gaggtcgagc ttctcgagca gaccggagtc
    38581 gagcagccgc aggccgccga agtagcggga ggacccggag gtcagccacg ggaaggtgtc
    38641 cgccttgacg gcgcgcgggt tgtggaacca ccggtagccg ccgaagagct cgtctgccga
    38701 ctcgccggag agcgccacgg tggaatgctg ccggacggcc tggaacagca ggtagaggga
    38761 gggccacatg tcgccccagt acgcgggcgg cagatccgtg gcacgcagca cggccgagcg
    38821 gacggccggg tcgagcagct cgcggctgtc gagcaggatc tcggtgtggt ccgccttcac
    38881 gtgccgggcg agctcacggg cgaagggcgc gtcggcttcg agtcgcaccg cgtccggctc
    38941 gaaccggtcg gaggccgccg agaagtcgac ggagaacgag cggagcctcc cggggccgac
    39001 ggtgccggcc gccagcgcgg tgacggcgga ggagtcgagg cccccggaca gcagcgtggc
    39061 cagcgggacg tccgacacca tctgccgccg gacggtgtcc tccagaagtt cgcgcaccgt
    39121 cctgacagtg gtgtcgaggt cgtcggtgtg cggcctggcc tcgagcgacc agtagcggtg
    39181 cttggtcaga ccggagcggg tgacccgcac gatgtgcccc ggccgtacct cgtacatccc
    39241 gcggaagacg gcgtgctccg gcgtcttcac catgtcgagc acttcgcgca ggccgtcggc
    39301 gtcgacctcc ctcggcgcca acgggttggc gaggatggcc ttgggctccg agccgaacag
    39361 gacaccgtcg cgggtcggga agtagtagag cggcttgatg cccatcctgt cgcggaccag
    39421 cagcagctcc tggcttcggg gatcccacag acccaacccg aacattccgt tgagccgctc
    39481 ggcgaacgaa gcaccccatt ggagataggc ccgtaggacc acctcggtgt cgctcttcgt
    39541 ccggaattcg tggccgaacg aggccaactc ctgccgcagt tcacggaagt tgtagatctc
    39601 gccgctgaag gtgaggacga tctggcccgc ggcgccggta ccgcccaaca tcggctgcgt
    39661 tccgccctcg atgtcgatga cggccagccg gcggtgcccg aaggccgcgt gccgatccag
    39721 ccaggtgccc tccgcgtccg ggccgcgaca ggccagcgtg tccgtcatcg cacgcaatat
    39781 ctcgtattcc cgcgacaggt cgcgaccgaa gtcgacccac cccgttacgc cgcacatcga
    39841 aatgtcacct ctccactacg caggacctga gtcccggtct gcatcggact gctggaatcg
    39901 cggagcgcct ctgctagggc ttgccgtggg ctgccgcggc gatcgcccgg cccaccacct
    39961 ggaccagctg ggagggcgtt tccgcctcga tgccgacgtc gtacgagagc ccgacggagt
    40021 actcccgctc gatcatcacg aatatgttga agagcgccag cgagtcgatt ccgagatcat
    40081 caaaagcgac gtcgtcgata ttgccggaga ggtcgatgtc gacggattca tcctgctccc
    40141 cgcactcttg gagaagctgc ttcagacggt cgagagagaa ctcgttcacc agtattcctt
    40201 ccggtggttc cagggcgtcc gccgggccgt tttccgacgt ggttatcagg gcgggcgggt
    40261 atttgggtga agccttgcaa ggtcgcccga aagcgtcaag cacttatctg acgaaggaaa
    40321 gtgacgatcg atcagaaccc gatcggcgtc gggtggtctg ctacgatgac gccggtccgg
    40381 gccccggcgg acaacttgat gaacctcaca ttttgacgag ttatgactga agtcgggaga
    40441 tgtatatgaa aacggtcgga attctgggat ccaccgggtc ggtcggtacc caggccgtgg
    40501 atgtggtccg gcgcaacacg gacaagttca aggtgctcgc cctggcggcg ggcgggggac
    40561 gtgtcgggct gctcgcggag caggtcctcg acctgagccc cgtggtggtg gcggtcgccg
    40621 gtgagggcgc ggccgacgag ctgcccgcag ccctcgcggc cgaggcgagc cggcgcggcc
    40681 tctccgcgac cgactggtcg gtgccgaaga ttctctccgg tcccgccggc gttgaggagg
    40741 tggcggccta cccggtggac gtcatgctca acggcatcac cggagcgctg ggcctcacgt
    40801 ccacgctcgc gaccctgcgc gcggggacga cgctcgctct cgccaacaag gaatcgctga
    40861 tcgtcggcgg tgaactggtg aagcgggagg cgcggcccgg gcagatcgtc ccggtcgact
    40921 ccgagcactc cgcactggcg caggccctgc gcgccggcgc ccgtgaggag gtccgcaggc
    40981 tggtgctgac cgccaccggg ggccccttca gggggcgggg ccgtgccgaa ctggcggacg
    41041 tgaccgtggc cgaggcactc gcccacccca cctggtccat ggggccggtg atctcgatca
    41101 actccgcgac gctggtgaac aaggggcttg aggtcatcga ggcgcatctg ctgttcgacg
    41161 tcccctacga ggacatcctc gtcatggtcc acccccagtc gacgatccac tcgatggtgg
    41221 agttcgtcga cggttcgacc atcgcccagg tgagtccgcc cgacatgcgg ctgccgatcg
    41281 cgctggggct gtcctggccc gagcgggtgc ctggagccgc gagggcgttc gactggacgc
    41341 agaaccaatc ctgggagctg ttccccctgg acgatgaggc gtttccgtcc gtcggtctgg
    41401 cacggcacgt cggcagcctg ggcggcagtg cgccggcagt cttcaacgcg gccaacgagg
    41461 tgtgcgtcga cgccttcctg gccggccgac tgccgttcct gtccatcgtg gacacggtcg
    41521 ccagggtggt ctccgagctc ggtgaccccg ccgcggacag tctggagacg attctggcgg
    41581 ccgatgcctg ggcgcgggca cgcgcccagg aactcaacgg cgctgcgcac cggtagctcc
    41641 gcgacgactc cgccgccaga ccgcggtccc ggcaaccggc tcaccgtctg cctcgggtcc
    41701 tcaaccgcgg tccctgatct cgcgttgatg acggagcgtc cttccttgcg tcggccgtgc
    41761 gtgtccggtg ggcggcgttc tcatcgcggt gccttgcgtt cctacgagga gaccaccagg
    41821 agccgccgct cgcggaagcc atcaccgttg aatgcgtcga ggagtcccgg ctccggcttg
    41881 ccggagagga gcagcaggtc gtggccgggg ctcgatgcgg ctgccggcca cgacagcggc
    41941 tcaccacgac ggccgcccca ggtgaccacc agcgaggggt ccgacaggga ccgcaggctg
    42001 aggaacctgt cggcgaactc acccgcgagg ttgggatcga gaacctggga ggggacgacg
    42061 ccgaacccca gacggctctt gaagttgaac aggccgggtt gaacgacatg cccgaagagc
    42121 gaggggtcgt tgcccaacga cgcgaactcc agcccgtggt cacgggcgaa ccggaaggcc
    42181 tcgccgtagg cggcccgcat cacccggccg gaacgcgcgt cggcggacgc cgcggagaac
    42241 cgcatctgca gcaccgactc tccccggcgt acccgccaga gggagccggc caccatggcc
    42301 tcaccggcgt agacgcagac actgacgtgg tcgggggcgg ctgcgagcag acgctcacgc
    42361 tcgcggcgcg cgaagttctt gccgcgtggc atccccgcga tctgctcgtc gtacacgtcg
    42421 aggaaggcgt cgagaacgtc ctcggccagg ccttgccgga cctccgcgcg gagctgctgt
    42481 tcctggacga accggcgcgc cagccgtccg ttcctccgct cggtacggga gagcccggac
    42541 tcgaactcct cctctgaatc cctcacctgg gcgcaccagt tcacccacct cggccgggcg
    42601 gtgaagccga gttccgccag agcggcgccg tcgagacctt cggagccggt cagcctggcg
    42661 atgtcgacgg gccggtcgca cgtcgtccac gtccggctcg ccgcttcctg ctggtcgacc
    42721 agcgcgacga cgaggccgtc ctgctcaacg atctccaact ccggctcctt ccagggcatc
    42781 gaccgccggg aggcgttcgc tgtggcgggt gtagacggcc cagatgacga ctgccacggt
    42841 ccagatgccc agggccggca gccaccgcag atagccgtcg agacggctcg ctccggcgaa
    42901 gaggaagccg gacagcggca cggccccggt gatgaacatc cggatggtcg cgttcgcgcg
    42961 gcccgcgacc tccaccggga tcgtctcctg ccggtaggtg atggaggcga cgttgctcac
    43021 ggcgaccgcc aggcactcga agacgtagcc ggtgagcttc gtcggaaggg ccggggtcgc
    43081 gacgagcacg agaccggcga gtgcggtcac ctgacaggcc aggatccggc gctcggggct
    43141 ccaggccgga aggatccgcg gggccatccg gctggccacc gcaccggcga acaggccgat
    43201 cgccatcacc ccggagatca ccttggcatt gatgccctgc tgtccgaact ccgtgaccag
    43261 caccggctcc agctggccga tggcgaggtt ggtcatcgac atcgtcacca ccaaccagat
    43321 gatctcgggc ttgacggccc agcggaatcc catcgcgaca tcgcggcgga tggacatctt
    43381 ctggtagctg gccggcaccc tgggcagcag cagcgccagc agggccgcac cgctgtacag
    43441 agcggcgatg cacagtgaag cggaggccgg tcccaatgcc gagaacgccg caccgccgat
    43501 gaggaggccg ccgaccttgg agaactcgat cgccgagttg agctttgcca ccgcggccgg
    43561 gcgggcaggc gcactgatca gtttcgggat gaggacgaac tgcccggtga tgttgctcgc
    43621 gacaccgccg aacccggaca ggagaacgag aagcgcgacc gacacctggc tgttcagcga
    43681 gaccgccagc agggcgaggc agacggcctg ctgcacctgg gccagcgcga acaccgcacg
    43741 ccggtcgaag cggtcgatga gcgccccgag gaacggcgac cagatgtagg tgatcccgcg
    43801 cagcgagaac gagatcaggg acatcgcgac ggagtccgtc tgcttgagga ccgccagcgg
    43861 aaccacgatc ccgagctgcc agtccgccac cttcgaagaa atcgacgatg cgatgaggat
    43921 ccgcaggatg cgcgagtccg tcgccggtgt cggtgcggcg tgctcagcca ctgcaggtgg
    43981 ccttgcgcgg tcagttggca tagaacgtac tccgtggcgg tcggtggggg agagagtgag
    44041 agggcatggg gaggtgtcag tcctgaccca gggcccagga cgtgatactc gtggccccgt
    44101 tgacgcggaa ctgctcccgg ccgaggatcg agttcaggat ccgtgcgctg cgccatgcgg
    44161 acaggctcag gttgggatcg gcgatgccgt gggagttctc cgcgaagctc tggacgtaga
    44221 tccggaggtc cgaagggccg tcccattcca gggagtagtc ctcatgcacc tcgaacccgt
    44281 ccgcccgcac ggtgatccgc tcccggaggg gttcgagata gtcggggaac ctgctgcggt
    44341 agccggtgca gaacacgacc acgtccaccg tgcagtgctc ctggcgattc cggtccgcgt
    44401 cgtgaaggtc cacgacgagc gcctcgccct cgcggcggag gtccgccacc cggtggttgg
    44461 ccaccagccg gtggcggagc gggcccccgg cgatgtccaa ctggtacagc cgtcggtaga
    44521 tcttccgcag caaggactcc gacacaccgt cgctggccag acgctggctt ccgagcacga
    44581 cggcgcggcg ctctgcggag agcgatcgga agtggtccac gtacgacggc gcgaaccact
    44641 cgttcgtgaa cggggagtcg tccatgggca ggaacccggc gcggctggag acccaggtga
    44701 gcgactcggg aagggaagtg tcgtcggaga gaaggtagtt gacgacctct gcgccgctct
    44761 gtccgccgcc cacgaccatg acgcgccggc cgctcgtggc cgggcggacc tgcatgaggt
    44821 cactgctgtg gagtacctgg ccgcctcgca ggccgacggc gaagtccggg aggtgcggct
    44881 ccttccccga acccagggcc agggtggtgg tcctggcggt ctcaccgctc tcgcacgtga
    44941 cctcgaagca gccgtcgccc agcgtcaccg acttcaccga ctgatcccag cggatcgacg
    45001 gcagctgctc ggcgacccac tggtagtact gctcgaactc catgcgggag gaattgagtc
    45061 cgttggcgat cagggcactg tagatgcgac ccttgtggtg aaggaagttc aggtaggagt
    45121 aggcgctcgt cggatcggcg agcgtgacca ggtccttgag aaacgagacc tggaggtcgg
    45181 cctcggggag catgagtccc ggatgccact gaaagcgcgg cttgacgtcg aagaagcgcg
    45241 tcgtgagtcc gccggcggac tgtgcgaggg cggcgagact caggttgaag ggacccaccc
    45301 cgatcccgac ggcatcgaag ctctgcaccg tagactcctc tctcacggcc tgtcccggcc
    45361 cggtgggcgg acggccggcg cgctcggatc gacatgactg ttggtcagag acgcttcccc
    45421 cgagcggtgt tcggtttcaa ggcgggccgc gaagccgtcc cggatctcgt cggtggtcat
    45481 cgcggccgtg gcgcgggaga aggtcgacgt ccctccaccc gccaccttcg cgacgatgag
    45541 gtggggaccg ctcgacctga gggccttcgc gagtgcggcg gtcacctcgt cgacggaccg
    45601 gcactcctgc gccgacacgt agccgacgga ccgggccact ccggcgaagt ccgtcgagtg
    45661 ggaggtggtc gcctgcccgc cggtcgactc gtacgtcccg ttgtcgaaca cgaggtggac
    45721 gaggccggcc ggtgcgcagg ctcccactga ggagagcgtg cccaggtgca tgatggccgc
    45781 gccgtcgccg tcgagcacga ccaccggccg cgccgtcgac tgcagggcga cacccagggc
    45841 gaacgcggcc gcgtggccca tcgacccctg catgtagaag tggttcttgg agccggtgac
    45901 accgaacagt tcacgggagg tgtagccggt cgtcgacacg acggcggcgt cgccgagcag
    45961 gggctcgatc gcgcggagta cctcgacgcg gctgacaccc gtcacaaccg ggtgggcctc
    46021 cggccggtga ctctcaatgg cccccttctg ggccaggacg aacacgctcc tccgggcggc
    46081 caggtgctcc tcggcccggt cgagcgcgga accgagctcc gtggcgtcgg ccggcacagt
    46141 gatgtgaggc acgcccacgg cgtccagcag cttgtgggtg gccgtaccca tgaccgcgtg
    46201 ctggggttcg tcctccgacg gatcgggcca gccgcgcagg ctcatgaaga ccaggacggg
    46261 gattccgtac gtctggacga gcgaggtcag cggattgatg aggttgccga ggccggagtt
    46321 ctgggcgatg accgccgatc gccggccggc gacgctcgca ccggcggccg ccgcgagcgc
    46381 ggcgccctcg ttggcggccg gtaggtactt cccctcgcgg gtcagtcgct cgatcggccc
    46441 ggagaagtac gagcacggca cgcccgcgac gaaggtgaca ccgtgttcct gcagcgtgtc
    46501 acagaagttg tcgttggaga tcatgcttcg agtgccagcc actcgtcgag cttctgcagc
    46561 gcgaagatgt cggagaccgg cgcgatgacg tcctcgacgc cgagtgacgt gccgtcctgg
    46621 cagatggtgc ggaaggtctc gcgaagcgcc tggacggtgg cgcgcagacc ctggttggcg
    46681 tagatcacca cggaggcccc gtgcttctcc gcctccgccg cggaccactg ggggtaggtg
    46741 gtcggcacga cgacgaccgg cagccggccg tcccagccgt cgaggaactc gacgatctcc
    46801 tgctggtcct tcttcttcga gtggatcagt accgcgtccg cccccgcctc ggcgtaggcg
    46861 tagcagcgct tcaacgcctc ctcgacgccg aggccgttga tcagtgcctc ggtccgggcg
    46921 atgacgtaga agtcctcacc tcgttgagcg gccttggccg tcccgatcct gcgcgcgaag
    46981 tcggacacgg gcagcaggtc gtgggaggtt gccgcgaagc tgttgacctt cgggtagacc
    47041 ttgtcctcga tgcacacggc ggtgatgcgg ccggcctcgt actcgcggac catgtgcgcc
    47101 acgttgaggt tgttgccgta ccccgtgtcg acgtcggcga ccaccgggat gcccaccgcc
    47161 ttctgcatgt tcgtggcggc ggcgaggtat tccgtcatgg tcaggacgct ggcgtcggga
    47221 aggcaccgag aggcggagat ctcgaagctc gatgcccaga ccgcctggaa cccggcttgc
    47281 caggccagag tcgagccgag cgcgtcatgg gcgccggcga ccctcaccaa gcctccttgg
    47341 gccatgagtt gacggaaggt caaatcttgt aaaagcacgt ctctccttgt gggggagtgt
    47401 ccaggtcgaa gcgcggtcgg cgcagacaag tggggaggcg ggtggccgcg cagcagcatg
    47461 ggcgtacggg ggcggtgccg agggcctcgg gggctccagg gcgacgcacg acgcttcaat
    47521 ggggtggacg atggtcctgg ccggcgccgg gaaggcgtgg tgacgggctt cggtgccgcc
    47581 gggcgggtgt tgccgagagg agcccgccgc gcgtcgcggt gagcggggcc gatccggcgg
    47641 tggtgccgcg gggcggcagc gcgggcgtcc ctgttcggga gggagtccgt cagttgtgaa
    47701 agaagtggtc agattttgcg caggccgggc tgcggacgat tacatgacct ctgacagaag
    47761 tcgggtcatt cgttcccgcc cgatgcgagg gcgggccgtc aatctgtgtg cgttgcagag
    47821 cggcggcgcg ccgaatggct gcggccgacg cgcggcgccg tccgccgctg ttcccccgtg
    47881 cacttgtgta atcccccgtc tggccgagat cgagttgaca agcgttgaac cttgatcacc
    47941 gtagccggtg aacgtgatat gtcaagtcgt gttcactgca tcctccaaag gcgcacccgg
    48001 ggcggggtgg aatgtctgtt tatttgcatg tttgcccctc tatcgagtgg ctgtcgcgca
    48061 ttcggtcgcc attacgccgg atcggcctcc ggataagctg ttgacgcatg gcgcgacgcc
    48121 tgcctagtct gccgtcggta tttagggttc catgtcggca accgccggcc tctcgctgtc
    48181 cccccaggtc gccgcacaat ttccgggcag gctggtcctg ggaggtggac atgaattcct
    48241 cgagtgcact ccgccctcct ccgctggagc tggcgaggaa tttggcattc gatcacctct
    48301 ttttttagga gtctccatgg ctgcgcagac aatcgcgggt ggtaccgggt ccggtgcggt
    48361 ggtgacgagg cacctcgttg tcggtgacgt ctcccaccag tactcggtga cgccggaccc
    48421 ggtcgccccg ctgctggtgg ccgagctgac caccgagccg ggcggggcca cgcgggcgat
    48481 ggagttcctc cgtcggccgg agaccgcctc ctccacggtg tcggtcatcg gggccgccgg
    48541 gcaggccggg accgtgacgc tcgggcgggt gcccgtcgaa ctctgggcct cgttcggggt
    48601 gaccccggag ttcgaggcgc agctccgtgg cgcgctcgag gccgccggca gccaggagct
    48661 ctccggagtc gacctgagcg cgctcgcgcc gctgatgctt ctacgaaccc accggggggc
    48721 ggagcggccc tttaccgagg tgctcatgtg cgggcgcgtc cggtctctcg gcacgctttt
    48781 cgtgcgggtc gcgaggtttg cgcacgccgc ggagtccgga attgccgagc tggtctccgg
    48841 ggcgctcgaa ctgtcggcct cccttcagga caacgtccgt atcgagggaa acgcctacac
    48901 gtcctacgaa aagggcatcg agatcgagca gaaggtgaac gtgtacgacg aggtctccat
    48961 ctggtcgctc acccagagcc tctggtcggc ggtggagaac ggtgaattca atgggttcat
    49021 taccgacccg gggtacgaac tcaccaggtg gcatttcatt cagcacaact tcgaggtgac
    49081 cgctccggcc tcggaggtcg gtcacattgc cttccaggaa accccgagcg gcacctatca
    49141 gctcaagctg aagaggtttg ccgaggatgc gctgcgccgt gaggagatcg tctacaaggg
    49201 gatcgatatt cccggcgcgg acttttccgg atatctgcgg cgggagtacc cggacatcga
    49261 gttcaggcgg ctgcccagcc tcacgcgcac gcgcttcgac atcaacgtcc agtcggtgat
    49321 caccggaaac tacttcggca tcgagacgga cgaggtcctg gtcctcgatc cgcggggtcc
    49381 gaagctgcgg caggtcgaga tggagtacct ggagacccgc tggcacgagg ggatggatcc
    49441 ctcgaccatc gacgatgaca tgaaccggct gaccgagttg gtggaggagc acctggcaaa
    49501 gcgcgggatc gccgccgagc gcactttcta ttccaagctc tccttcctca aggactgcgt
    49561 ccgcaggtcg gaccaggatg tcctcggtgt ctgacggatc ttcaaaaacc ggccatgcag
    49621 gaaagttcca gccggcggag accgacggga ccgcagggag gtgtgaagtg aagaccagta
    49681 ccaggcttgt ccgctcgttc cgggacatca ccggtggcga caccgatttg cggcgcccgg
    49741 tggtgacgct gttcagcggc ggccttgaca gcacttacct gctctaccga ctggcccggg
    49801 caggggccac ggatgtgcgg gccatcagcg tcggcctggg tggtgacgag caggcggcac
    49861 agctgcagcg gattgcggac aagcttggtg tgcaggtcca agtgacggac gcccgggagg
    49921 agttcgtgga tgaattcgtc cggccggcga ttgccgccca cgcggtctac ctcgacaccc
    49981 atcccatcag ttcgtcgctg agccgcccgc tgatcgcccg cgtcgcggtc ggagcggcgc
    50041 gcgagcacga cgcgcagatg attctgcaca ctgcgaaccg ctcgcagaac acgctccgca
    50101 ggcttaacgg agcactcgaa cttctcggct tccagggccg cttcggaagt ccctacgacc
    50161 tgaacccggt ggaccgggag gtgaagatca aggagctcca gtccgtcggc ctcgatgaga
    50221 tggccgagcg gtcggccagc ggagactcca acctctggtg cagggagttc gagtccggca
    50281 tcctggacga ccccgaggac cacgtcgttc ccgagtccta ctatcggtgg agcgcccggc
    50341 ggggggtggc cccggcgccc gagcatctgg agatcggttt ccgtcagggg attcccgtcg
    50401 cggtgaacgg cgaggagctc cccctcgccg agatcatcga gcggctcaac tggactgtcg
    50461 gagctcacgg gatcggccgc tacaccggcc tggagcacct tcccggcggg gtcaaggttc
    50521 tcgaagtgcg ggagatgccg gcggcccggc tcctgatggc atcgcgccgg caccttgaga
    50581 cggcggttct tgaggccgag tccctccgcg agaagatgca cgtggagcag gtgtgggtcc
    50641 gtgaggcgct cgaaggccgc tggttcggcg aactccgccg ggcctgcgac tcgttcattg
    50701 ccgagctcgt cgcgtcggtc accggcacgg tgcgctggcg gctctccgcg cggggcgcct
    50761 cgaccacctc catcgtcgcg gcgagccccc ggtacgtgcg caatcgggag gactgggaac
    50821 aggcctccat ccaggcggag atctcccact acgaagcggc ttcggacggc gacatcaggg
    50881 gcgggaaatg gtgaccaacc agaaatcgaa cggctctgcg cggcagctgg tggtgatcga
    50941 tgccgatgcg cgggccgcgc gggccgcgcg caccctcggc tgccgcatcg tgtacgtgca
    51001 gcaacccggt tcacccgtcc acgagttggt cgacgacgac tcgggctact actcggtgga
    51061 cttcaccggt ccgaagttcg ccggattcgt cggggaggtg cttcgtccat tgctgccgac
    51121 ggcggccgtc tccctcaccg cccaggggct ggcggcggcc gacgtggtga actcgctgct
    51181 cgggacggcc ggcacaccgc ccgggatcct gcagcggctg accggaacgg ggcccgagtc
    51241 gtcggacggc ctggacctgg tgcgactggc cctcggctgg ccgctcgggc tgcgcgaagc
    51301 cgactgcacg gtacccgccc gcactctgga aggggacgga cagtgaagcc cgccgcgttg
    51361 ttcatcaaca accacccgta ctcgcacttc gcccggggcg ggaagtacat cctgccgacc
    51421 tccgagatcg acatccacct cgtgacgcgc aaccggcggt acggaggggt cagcggattc
    51481 gcggaccacc cgctggacca cgtctcgctg tgcggcatcg acgacgagga cgactggcgc
    51541 gccgtctgcg aatggacgct gcgcaaccac ccgatcaccc gtgtcatcgc cgtccacgag
    51601 cgtgccgtgc tgttggcggc ggagatgcgc tccaagttcg gcctgcccgg catgcagtac
    51661 gagaccgcgg tgcggttccg cgacaaggtg cggatgaagg aggccgtgcg cgcggccaac
    51721 gcggcgacgg tgccggggtt ctccgcactc gacagcggtg acgacctggc gaacgtcgac
    51781 tggagcaccg ggcggaaggt catcaagagc cgtctcgggc tcgccgccaa ggacctgtac
    51841 atggtcgaca cgctcgaaca ggcgcggcgg gtcgtcgcgg ggctcgatct ctccggctcg
    51901 cactacgaga tcgaggagtt cgtgaagggc tggatctacc actgcgactc cgtggtccag
    51961 ggcggccgta tcagattcag cagcgtgggc aagtacctcg ccgacccggc gagctaccgt
    52021 cctggaggga tcttcggtac ggtcctgctc accgacggcg agttggtgaa gcgcatcacc
    52081 gagctcaacg agcgcgtgct cgccgggctg ggaatcgagg acggcacgac gcacctcgag
    52141 ctgttccaca ccgcagacga cgaactcgtc ttctgtgagg tcgccgggcg gcctcctggg
    52201 ggcatcatcc ccccggtgat cgagcagcag tacgggttcg acatcgtcga gacgcaaatc
    52261 cgtatcgatg cgggaatcga tttctcgctg ggcagcgtcc ctgagtcgcg acacggaggg
    52321 gcgtccggct tcatcgcgtt ctacc
//
