LOCUS       NZ_CP026498            23039 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. CB01881 chromosome.
ACCESSION   NZ_CP026498
VERSION     NZ_CP026498.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CB01881
  ORGANISM  Streptomyces sp. CB01881
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     A 3-hydroxy-3-methylglutaryl-CoA synthase gene based probe for the
            discovery of the acyltransferase-less polyketide synthases
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2018) Xiangya International Academy of
            Translational Medicine, Tongzipo, Changsha, Hunan 410000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002953255.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 02:39:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,978
            CDSs (total)                      :: 7,904
            Genes (coding)                    :: 7,565
            CDSs (with protein)               :: 7,565
            Genes (RNA)                       :: 74
            rRNAs                             :: 5 (5S)
            complete rRNAs                    :: 5 (5S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 339
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 339
            Pseudo Genes (frameshifted)       :: 124 of 339
            Pseudo Genes (incomplete)         :: 251 of 339
            Pseudo Genes (internal stop)      :: 10 of 339
            Pseudo Genes (multiple problems)  :: 45 of 339
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:44:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8492131
            Orig. end                         :: 8515170
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026498.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23039
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="28"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..23039
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23039
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13039](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13039)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            complement(811..2187)
                     /locus_tag="C2142_RS27135"
                     /old_locus_tag="C2142_27155"
     CDS             complement(811..2187)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013594.4"
                     /locus_tag="C2142_RS27135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27155"
                     /product="M48 family metallopeptidase"
                     /protein_id="WP_148645369.1"
                     /transl_table=11
                     /translation="MPTPPVPTPAVPAPAAAPAAAQAPATAPQTCPRCAAALDADPRFT
                     AWCPHCDWNLTPGPERAAATRHEAAAAARTDRLYEDVAAGRTATAGRRDWLAASAIATV
                     VHLATASLFSWGLWLLVTGNTPLRCLGAIVLAVVVLLRPRLGRAPRGEGVLDRAQAPAL
                     YGLADRVAAEVGAGPVGVIRVDGEFNASVGAVGLRRRSVLTLGLPLWEALGEQERVALL
                     GHEFGHRVNGDHRRGLWLGSAIHAIAHWHELARPRTHAGGGVGLMHLLLHFTDLVTNAV
                     LGVVAWMLRRVFGLLDRLTVRAGQQAEYHADTLATRVASTGATRRMLRTLLLDGTVDTV
                     VTRVRAELQGRPRAPRRGADPAATGPAPRAAATEELWEKLRDHLAAVPPLEHERLLRRS
                     ALDRGAVDSTHPPTHLRLALLDRRPDLPAAVTTTPAEAAAISAELAPHRTRIARTLLAG
                     "
     gene            2359..3447
                     /locus_tag="C2142_RS27140"
                     /old_locus_tag="C2142_27160"
     CDS             2359..3447
                     /NRPS_PKS="Domain: PKS_ER (13-354). E-value: 2.2e-13.
                     Score: 42.0. Matches aSDomain:
                     nrpspksdomains_C2142_RS27140_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135539.1"
                     /locus_tag="C2142_RS27140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27160"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_148645370.1"
                     /sec_met_domain="ADH_N (E-value: 3.2e-27, bitscore: 93.4,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.5e-24, bitscore:
                     83.5, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAILHKTGQDTLDVRDDVVAVGFGPGKVRVRLRAASLCHSDLS
                     AMSGVLPQPAPFVPGHEGAGDVVEVGEGVTGVAAGDRVVLCWMAPCGRCAHCERGRGHL
                     CVSSLRRLGAPGFRFDGGGAPVDASGFYGTGAFAEEVVVERDAVIKVPADLPYELAALI
                     GCGVTTGIGAAVHTAQVEPGSSVAVIGAGGVGVATVQGARVCGAGRIAVVDPVVSRRER
                     ALAFGATDALAPEELKAVAKGLPGGGFDYVFEAVGRAATVRAGYDAARRGGAVVVIGAG
                     AQDDLAQFTMGELFFNEKRLLPSLYGGTSVPRTIALVVDLWRAGRIDLAGMITHRVGLA
                     DVNEAVAQMRGGEALRTVVTLD"
     aSDomain        2398..3420
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS27140_PKS_ER.1"
                     /evalue="2.20E-13"
                     /label="C2142_RS27140_PKS_ER.1"
                     /locus_tag="C2142_RS27140"
                     /protein_end="354"
                     /protein_start="13"
                     /score="42.0"
                     /tool="antismash"
                     /translation="LDVRDDVVAVGFGPGKVRVRLRAASLCHSDLSAMSGVLPQPAPFV
                     PGHEGAGDVVEVGEGVTGVAAGDRVVLCWMAPCGRCAHCERGRGHLCVSSLRRLGAPGF
                     RFDGGGAPVDASGFYGTGAFAEEVVVERDAVIKVPADLPYELAALIGCGVTTGIGAAVH
                     TAQVEPGSSVAVIGAGGVGVATVQGARVCGAGRIAVVDPVVSRRERALAFGATDALAPE
                     ELKAVAKGLPGGGFDYVFEAVGRAATVRAGYDAARRGGAVVVIGAGAQDDLAQFTMGEL
                     FFNEKRLLPSLYGGTSVPRTIALVVDLWRAGRIDLAGMITHRVGLADVNEAVAQMRGGE
                     A"
     gene            complement(3534..3713)
                     /locus_tag="C2142_RS27145"
                     /old_locus_tag="C2142_27165"
     CDS             complement(3534..3713)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007497991.1"
                     /locus_tag="C2142_RS27145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27165"
                     /product="hypothetical protein"
                     /protein_id="WP_148645371.1"
                     /transl_table=11
                     /translation="MSDTLTDTTGPAVNGTDADETTAEDTASHGRHRGRTAADDSPEAD
                     PHGRHRLGAGADQG"
     misc_feature    3711..3726
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.31"
                     /tool="antismash"
     gene            complement(3885..5840)
                     /locus_tag="C2142_RS27150"
                     /old_locus_tag="C2142_27170"
     CDS             complement(3885..5840)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946994.1"
                     /locus_tag="C2142_RS27150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27170"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_194235814.1"
                     /transl_table=11
                     /translation="MGRHSAGHGASQGTGRRDGHRDGHGHGHSAVLGTGHHTGGGYGHG
                     VPDAGDPGRRRPPGWALLGRQLATTRGALWRLLGWSGVEALPALTSGLMVSAAVDRGFL
                     AGRPGVGVAWLAGFGVVTAARAYAARAGFPYLAAVVEPLRDALVERVVRGALARPHADP
                     AEVARLTEQVESARQLTATLLRTLRGVGVTLAAALAGLALLAPAVLPLVLVPLLAAGLL
                     FARLLRPLVERRRAVVLAEERLAAEAGRALHGLRDIQATGSRDRTAEALAATAGNSAAA
                     SRALGRAAALRSLVVALGGRLPVLAVVAASPWLLGDGGLTPGELLGVATYLLQQLDPAV
                     RTLAGTVGGWLLSLAVVLDRLATTSGEPEPRPAPADPSSPAPPVPPAPPPPPPPTAVGL
                     RLTALRYAHGPAAEPVFSGLDVALAPGEHLAVVGPSGTGKSTLAALLAGLLAPLDGEVG
                     VGGVRPHLLPGPERSRLVALLPQEAYVFPGTVRANLCWPAPPAGARPSDAQLAHATALL
                     GADGLVARLGGPDAELADPGALSAGERQLLALVRTYLSPAPVVVLDEATCHLDATAEDR
                     VERAFAARPGILVVVAHRISSALRADRVLLLDGGRGVLARHGDLQVLSPLYRELVGHWL
                     GSAGQRGAASFVGRPT"
     gene            complement(5840..7498)
                     /locus_tag="C2142_RS27155"
                     /old_locus_tag="C2142_27175"
     CDS             complement(5840..7498)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998310.1"
                     /locus_tag="C2142_RS27155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27175"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_148645372.1"
                     /transl_table=11
                     /translation="MPRRPTGWTLALAVALPAEAATTLALPPALAGAVDAALDRDAGHC
                     ASALLALVVGTAAAANALAAAAGPACAAEATAGLRGRLVRHLLALGPGGRLWRDGPPPG
                     DLAARLVGSAADAGGRLPAVLGAATALLTSAGAIVGLGVLSPWLALAFFGGVVPGVVLI
                     RLFLREAGQVFVRYQEVQADLAARLTGALTGLRSIHAAGAQRSEEARVLEPLPALSAAG
                     HALWAAQRRTAWQATLLIAVVEVAVLATAGALVAAGTLAPGALAAAAGWAALGAGLFEQ
                     VEALVGVAHARAGQVRVDELLALAPATGGAAVLPEGGAGELAFRGVVVRDGDRVLLGPL
                     DLTVPGGCTVALVGRSGCGKSLLAALPGRLRDPDEGRVLVDGVPVGELAAPELRRAVGY
                     AFERPALTGRTVRDALDGAGPAAVAAARADGFLRRLPAGWDTPLDELRLSGGELQRLGL
                     ARLLARPARVLVLDDATSGLDLATEYQITEALDRATHGSTRLVVAHRESAAARADLVAW
                     LDVGRLRALAPHAELLADPDYRATLSGTALEAATA"
     gene            complement(7646..7789)
                     /locus_tag="C2142_RS27160"
     CDS             complement(7646..7789)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038147.1"
                     /locus_tag="C2142_RS27160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VenA family class IV lanthipeptide"
                     /protein_id="WP_153882823.1"
                     /transl_table=11
                     /translation="MENMVDFETDLAALQELPETESVELTGHGGGCQYTCLILTCLIFT
                     IS"
     gene            complement(7956..10004)
                     /locus_tag="C2142_RS27165"
                     /old_locus_tag="C2142_27180"
     CDS             complement(7956..10004)
                     /NRPS_PKS="Domain: Abhydrolase_1 (452-583). E-value:
                     2.3e-10. Score: 32.4. Matches aSDomain:
                     nrpspksdomains_C2142_RS27165_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012546.4"
                     /locus_tag="C2142_RS27165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27180"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_148645373.1"
                     /sec_met_domain="PF00561 (E-value: 1.9e-07, bitscore: 29.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.5e-19, bitscore:
                     69.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVATRSATHALRRLSFSFAADGSHAACLASAADGGWYAESWDLP
                     ASGPAVPTPLALPGNRSENLRSQLIALPDGSVLVCRHDGERHELVALDAAGPGCEPATT
                     ERRLAAFKRPGLRLLPLPASAAGSPAADGARTADGARVPVAVALGTDTRPATTVWLVHA
                     DGSEPRQVAEIPGLHGGGVWLDRAGALLALDRVGAGVVRTVVLDLRSGTVTPLLEIGER
                     SNDRLVLFDPDSRFAMVRSDAPGTDRLGWGLLGGGGPLRFPECLHVSGMLLRPVALRPA
                     PEGVRVVVQIDHGAGSALALWRPAAGRLDPLPVPPGRLGAAGHWSEAGLRMPYSSPDHP
                     TALATLDVDALLAHGPASAGPGPAPLPLQLAPLGTGLPGSGLPGPWRDVVLPWQPGGAR
                     TAPAAPAGWRLDGSTPPGDGGRWHPAQSIELAGPAGPLEAVVYGGDAWLSSPHLVLALH
                     GGPADAWRLEFDPALQRMAAEGLAVVAPNQRGSTGYGVAHAMAIRGAWGGPDLDDVLYL
                     LDGLAGQRAALGLEPPALFGVSYGAFLALLAAAHAPAEQVARCAVVAPFLSGARLLSEA
                     ASPVRALTTRLGGGEPIADARGPRDVLQLAHRLNAPLLVVHGDRDEVVPVSQSRSLRHE
                     LLRIGRSEGADFRYVEAAGAGHEVLAEDGAAVLHELLAAFLRTGRPG"
     aSDomain        complement(8256..8648)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS27165_Abhydrolase_1.1"
                     /evalue="2.30E-10"
                     /label="C2142_RS27165_Abhydrolase_1.1"
                     /locus_tag="C2142_RS27165"
                     /protein_end="583"
                     /protein_start="452"
                     /score="32.4"
                     /tool="antismash"
                     /translation="LVLALHGGPADAWRLEFDPALQRMAAEGLAVVAPNQRGSTGYGVA
                     HAMAIRGAWGGPDLDDVLYLLDGLAGQRAALGLEPPALFGVSYGAFLALLAAAHAPAEQ
                     VARCAVVAPFLSGARLLSEAASPVRAL"
     gene            complement(10001..13039)
                     /gene="lanL"
                     /locus_tag="C2142_RS27170"
                     /old_locus_tag="C2142_27185"
     CDS             complement(10001..13039)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="C2142_RS27170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27185"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_148645374.1"
                     /sec_met_domain="Pkinase (E-value: 2e-13, bitscore: 49.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5.6e-34, bitscore:
                     116.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTGTSLRTAGGRGSAGHGPAAAGSWPEVTRTALAGAGGRGGGGD
                     WEVTAEGFWCTARPSAGELAGEGWKIHVSAASAVGGAVLAAVTEVLADDPCAFKFAAGP
                     EQLHELNSRNSDRGSAGKFITVYPEGEEQFRRLAAALHRATDGLPGPVVLSDRPYRPGS
                     RVHYRYGAFAARAELGNDGGYRSMLRGPDGELVEDVRGATYRCPPWARDPLAEGRGAEG
                     RGAGADRRGPGAAKPAAARRGAGGVLLAGRYVITGAIRHSAKGGVFLGRDTDAGAEVVV
                     KQARAHIEVDRSGTDARAALRHEAALLARLEGLGLAPRPVELIEQDDSLFLVQERIAGQ
                     PLGGWVAARLRRDGSPDVDWAEAGPLVHALLDLVERVHELGLVLRDLSPGNVLVQPDGT
                     LRLVDLELAAEAGRRAGSAGTPGYRAPEQGPGRLALVDGAPSDGGPAEGGAGGAGGTGA
                     GGVCAAEPTADLYALGGLFFLLATGHDPLLPEDLPCARPVADRLGRWLALAARGGDTAR
                     RLAPLVLGLRAEDPEQRWRLHRVREALTGGPATTAGGSGDSGTDTAGGSGDSCTDTAGG
                     PQVSAVETRPTGSGGTIVDRVLHDGLRHLAATATPLRRDRLWPAVPAGERSDPCNVQHG
                     AAGVLALLARAAVTGGLPAGVRDEARETTRTAVEWIERRCAAEPVVLPGLHFGRSGTAW
                     ALLDAAGSLGDHALAGRAAGLARGIAVKWPNPDVCHGAAGAGHLQLRFAAEDPGTGAAR
                     EFLARATACGHGLLAAARPSPYGTVWPVPEDFDSALAGITHLGFAHGVAGVGAFLLAAG
                     EATGDQALLAGAVEAGRTLARTVRRETVGGTRESAWWPQDAGDPEHVRLAHWCSGASGA
                     GTFLLRLWQVTGDATARELALAAGRAVLAGRWHCGVSACHGLAGNGEYLLDLAGFTGDA
                     EFRAGAEELAQLITARSALRNGLLVLPDETGTGCSAAYGTGTAGPLAFLLRLCHGGPRL
                     WVDPVPPVPSGELPPPAGETRAT"
     misc_feature    complement(13079..13095)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.18"
                     /tool="antismash"
     misc_feature    complement(13312..13328)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.12"
                     /tool="antismash"
     gene            13645..14481
                     /locus_tag="C2142_RS27175"
                     /old_locus_tag="C2142_27190"
     CDS             13645..14481
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0051540 - metal cluster binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010351913.1"
                     /locus_tag="C2142_RS27175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27190"
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="WP_148645375.1"
                     /transl_table=11
                     /translation="MPKLSEVIAALEEVYPPQWAESWDAVGLVCGDPQAEVGRVLFAVD
                     PVQAVVDEAVEWGADLVVTHHPLYLRGTTSVAATTFKGRVVHTLIQSGIALHVAHTNAD
                     HADPGVSDALAEAVGVRVTGPLVPDPTDPLGRRGAGRIGLLEPPLTLSVFAAQVARGLP
                     ATAAGVRVSGDPNRLISRVAVCGGSGDSMFAEVRAAGVDAYLTADLRHHPASEAAEAAP
                     VALVDAAHWATEWPWLALAERALHGAAEKRGWAVETKVSHKVTDPWTAHASMSFTA"
     gene            14505..15248
                     /locus_tag="C2142_RS27180"
                     /old_locus_tag="C2142_27195"
     CDS             14505..15248
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018839080.1"
                     /locus_tag="C2142_RS27180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27195"
                     /product="C4-type zinc ribbon domain-containing protein"
                     /protein_id="WP_174315754.1"
                     /transl_table=11
                     /translation="MNAAPADQIRLLDLQAIDSKLDQLAHRRRSLPEHAEIEKATADHT
                     ALKDLVVAAQAQQGDTTRELTKAEQDVEQVRARSARNQQRLDSGAITSPKDLENLQHEI
                     GSLAKRQGDLEEVVLEIMERLESAQTRVTELTARLEHSSVVLKEAEARRDAAFAEIDGE
                     ADRVRRERETVAVVIPADLLKLYTRLREQQGGVGAARLFQRRCEGCRVEFAVSDLNAIK
                     AEPKDAVVRCDNCGRILVRTAESGI"
     gene            15253..16410
                     /locus_tag="C2142_RS27185"
                     /old_locus_tag="C2142_27200"
     CDS             15253..16410
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135533.1"
                     /locus_tag="C2142_RS27185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27200"
                     /product="bifunctional RNase H/acid phosphatase"
                     /protein_id="WP_148645376.1"
                     /transl_table=11
                     /translation="MAGRRFIVEADGGSRGNPGPAGYGAVVRDGDTGQIIAEAAEFIGH
                     ATNNVAEYKGLIAGLKAAREIDPDASVDVRMDSKLVVEQMSGRWKIKHPDMQPLAAEAR
                     GVLPRGQVKYTWIPRERNKDADRLANEAMDAGKAGRQWEPKPLKAASPVVVEPAAEPPL
                     EKAVPKAGWAAAADLGTPTTFVLLRHGETHLTPEKRFSGSGGSDPELSEKGRWQAERAA
                     EALAARGSVQAVVSSPMRRTRETAEIVAARLGLEVRYEEGLREVDFGAWEGLTFAEVQQ
                     HYPDDLNAWLGSPRAKPTGSGESFTTLTHRAGVARDKILARHPGKTVLVVSHVSPIKTL
                     VRLALGAPPDSLYRMELSAASLCAVQYYADGNASVRLLNDTGHLR"
     gene            complement(16480..17265)
                     /gene="yaaA"
                     /locus_tag="C2142_RS27190"
                     /old_locus_tag="C2142_27205"
     CDS             complement(16480..17265)
                     /codon_start=1
                     /gene="yaaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009064698.1"
                     /locus_tag="C2142_RS27190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27205"
                     /product="peroxide stress protein YaaA"
                     /protein_id="WP_148645377.1"
                     /transl_table=11
                     /translation="MLVLLPPSEGKAASGDGVPVALDGLSLPGLTAAREQVLEALVGLC
                     RGDEDTAAEVLGLSPGLRGEIARNAALPTAGALPAGEVYTGVLFDNLGLATLDEAAYDR
                     AARSLLVFSGLWGAVRIGDRIPPYRCSMGVKLPGPGALGAYWRGATASVLPEVADGLVL
                     DLRSSAYAAAWKPAGEVVSRTATVQVLQERNGRRTVVSHFNKATKGRLVRDLLVAGAEP
                     KTPGELVDALLGLGHRVEVAAEGTARKPWQLDVVVTEIH"
     gene            complement(17365..17787)
                     /locus_tag="C2142_RS27195"
                     /old_locus_tag="C2142_27210"
     CDS             complement(17365..17787)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024559.4"
                     /locus_tag="C2142_RS27195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27210"
                     /product="DUF3995 domain-containing protein"
                     /protein_id="WP_162002553.1"
                     /transl_table=11
                     /translation="MAGVLAATGALHAVWAVTPWPLRTPEEFADTVVGTGDGVPPAAAC
                     VAVAGLLGSAAYLVGAEAGVLPKAGPAWVRRQGVRAVAGVMLARGAGGLAMFGGGLVAR
                     SERFRRLDTRYYSPLCLALGTGAAVVAVAGGARRGE"
     misc_feature    17970..17990
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.45"
                     /tool="antismash"
     gene            18001..18351
                     /locus_tag="C2142_RS27200"
                     /old_locus_tag="C2142_27215"
     CDS             18001..18351
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS27200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_27215"
                     /product="hypothetical protein"
                     /protein_id="WP_148645379.1"
                     /transl_table=11
                     /translation="MTLRPLDLVPGDDDAVEESLPVRLPAGLPAETRQALEFALEAAAQ
                     AVLAGRVRVTGAPDEDDRAELAFDVRQSELPDALAEPARAAAEPGRAERRAAMVARIRE
                     ANAETLERLKDL"
     gene            18348..18743
                     /locus_tag="C2142_RS27205"
                     /old_locus_tag="C2142_27220"
     CDS             18348..18743
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124908.1"
                     /locus_tag="C2142_RS27205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27220"
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="WP_148645380.1"
                     /transl_table=11
                     /translation="MNATGGTNDVEYLDLEDVTYLAGGPENIRDLGALLSALGRPQASL
                     FGGDAYPDLWTKAAALGQSLARNHPLIDRNKRTAFEAMLLFLDYNDEPYGDPHPDDAVA
                     FMLRLATGGYDESVALAAKDLRSLLGR"
     gene            18828..20297
                     /locus_tag="C2142_RS27210"
                     /old_locus_tag="C2142_27225"
     CDS             18828..20297
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983872.1"
                     /locus_tag="C2142_RS27210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27225"
                     /product="RNB domain-containing ribonuclease"
                     /protein_id="WP_148645381.1"
                     /transl_table=11
                     /translation="MPRRKLRVKAADSARINAELTELRARLEIHTEWPDPVLAEAEEAA
                     RTPRLPEYDATGLPLLTVDPPGSRDLDQAMHLAHRPGGGYRVHYAIADVAAFVRPGGLI
                     DAEARRRVQTLYFPDHRVPLHPARLSEDAASLLPGETRPALLWQLDLDADGAVVLADLR
                     RALVRSHRRLDYAAVQRAVDAGGADEQPALLATVGRLREEQERARGGISLPVPEQEIEE
                     TLHGYVLGYRAPAPADGWNAQISLLTGMAAAELMLDAGVGLLRTLPAAPPEAYQRLRRT
                     ARALDVDWPDGLPYPELVRSLDPDVPLNAAFLNECTGLLRGAGYHAFDTAQGLPVPADP
                     AHAALAAPYAHCTAPLRRLGDRFAQEVCAAVAAGESVPDWAREALPAVPSLMAGGDRRS
                     AEVERACVDLVEAELLAGREGEDFPALVIDVDEQRPARGTVQLREPAVRARCERPDDAS
                     GAGRGLPLGGEVLARLTVADPATRTVRFTAV"
     misc_feature    complement(20326..20340)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.37"
                     /tool="antismash"
     gene            20430..21872
                     /locus_tag="C2142_RS27215"
                     /old_locus_tag="C2142_27230"
     CDS             20430..21872
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0009410 - response to xenobiotic stimulus
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009314131.1"
                     /locus_tag="C2142_RS27215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27230"
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="WP_148645947.1"
                     /transl_table=11
                     /translation="MLVLAICCLSLFIVGLDNTVVNIALPAIQKDLDAPASGLQWIIDA
                     YTLVLASLLMLFGSVADRFGRRRVFQTGLLLFVLGSLLCSLAPSLEWLVVFRAVQAVGG
                     SMLNPVAMSIITNTFTEPRERARAIGVWGGVVGISMALGPLLGGFLVDGAGWPSIFLIN
                     VPVGLLACVLTARYVPESRAPRARRLDPVGQLLMVALLGCGTAAIIEGPEHGWTSPLIL
                     ALAATALAALTAFPFWERRVAEPLVDPRFFRSAPFTGATVTAVCAFAALGGFLFLNTLY
                     LQNVRHYSPVEAGLWTLPMAGMMLVCAPVSGRIVGSRGPRGPLVAAGLGLTASGLLLTR
                     LAADSPAALLLAAYALFGFGFGMVNAPITNAAVSGMPRAQAGVAAAVASTSRQVGQSLG
                     VAVIGTVVTSAVVGPLVTGFAPASHAGWWIVTGLGVAILLLGLVTTTAWATGTAARVAA
                     RLGGEAPVVRPAVREAPPERLP"
     ncRNA           21886..22284
                     /db_xref="RFAM:RF00010"
                     /gene="rnpB"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="C2142_RS27220"
                     /ncRNA_class="RNase_P_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="C2142_27235"
                     /product="RNase P RNA component class A"
     gene            21886..22284
                     /gene="rnpB"
                     /locus_tag="C2142_RS27220"
                     /old_locus_tag="C2142_27235"
     gene            complement(22373..22630)
                     /locus_tag="C2142_RS27225"
                     /old_locus_tag="C2142_27240"
     CDS             complement(22373..22630)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139226.1"
                     /locus_tag="C2142_RS27225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_27240"
                     /product="Prokaryotic metallothionein"
                     /protein_id="WP_148645382.1"
                     /transl_table=11
                     /translation="MAICVTCGNDYWLAFEIKTITGDVYTFDSFECAMEKLAPRCEQCQ
                     VRIVGHGVEVAGRFFCCANCARVNGGLGEQIRDAVGAHPA"
ORIGIN
        1 tcgaacccct cggcgagcgc gcgcaggtac acccggtagg gagcctgccc gccgtccgcc
       61 gggtcgggga agacgtcgtg caccaccagc aggccctcgg gcgccaggtg cggcgcccag
      121 ccctcgtagt caccggtggc gtgctcgtcg gtgtggccgc cgtcgatgaa gaccaggccg
      181 aggcggccgc cccagagtgc ggcgatctgc ggcgaacggc cgaccagcgc caccacgtgc
      241 tcctccagcc cggccgcgtg cagcgtgcgg cggaagcgcg ggagcgtgtc catccggccg
      301 acctccgggt ccaccagcgt cgggtcgtgg tactcccagc cgggctgctg ctcctccgac
      361 ccgcggtggt ggtcgacggt gagagccacc gtcccggcct cccgggccgc cgccgccagc
      421 aggatcgccg agcgcccgca gtaggtgccg atctccagca ccggaagccc cgtccgccgg
      481 gcggcggtca ccgccgccgc gtacagcgcc agcccctcgt ccaccggcat gaacccggtc
      541 gcggcctcga acgccgccag cacctcggcc ccgggtcgcg tgttctccag gaggtcggac
      601 atgctgcagc tccttgccgg ggggtggggg tggtcggtac tccgtgctcg ccgtcggacc
      661 ctactcgacg gtacgccccg tcgtcccgcc cgccccgacc ggcggggagc ggcgcggagc
      721 ggcgggcccg gcgccgtcgg cctcccgcgc cgggtgtcgg cagcgggggc cgccggccgc
      781 tccctcagcg ggctccgccg gccggtcccg tcagccggcg aggagcgtac gggcgatgcg
      841 ggtgcggtgg ggagccagct cggcgctgat ggcggcggcc tcggcgggag tcgtggtgac
      901 ggcggccggg aggtccggcc tccggtcgag gagggccagc cgcaggtggg tcggcgggtg
      961 ggtggagtcc acggcacccc ggtccagggc ggagcggcgc agcaggcgtt cgtgctccag
     1021 cggcgggacg gcggcgaggt ggtcgcgcag cttctcccag agctcctcgg tggccgcggc
     1081 ccggggggca ggccctgtcg ccgcggggtc cgcgccgcgg cggggcgcac gggggcggcc
     1141 ctgcagctcc gcgcgcacgc gggtcaccac ggtgtcgacg gtcccgtcga gcagcagcgt
     1201 ccgcagcatg cggcgggtcg ccccggtgga cgcgacccgg gtggccagcg tgtccgcgtg
     1261 gtactcggcc tgctgtccgg cccgcacggt gagccggtcg agcagcccga acacccgccg
     1321 cagcatccag gcgacgacgc cgagcacggc gttggtgacg aggtcggtga agtggagcag
     1381 caggtgcatc aggcccaccc cgccgccggc gtgggtgcgc ggccgggcga gctcgtgcca
     1441 gtgtgcgatc gcgtggatcg ccgagccgag ccagaggccc cgccggtggt cgccgttgac
     1501 ccggtggccg aactcgtggc cgagcagggc cacccgctcc tgctcgccga gcgcctccca
     1561 gagcggcagg ccgagggtga gcacgctccg ccggcgcagc ccgaccgccc ccacactcgc
     1621 gttgaactcg ccgtcgaccc ggatcacccc gaccggcccg gcccccacct cggcggcgac
     1681 ccggtccgcc agcccgtaca gggcgggtgc ctgggcccgg tccagcacgc cctcaccgcg
     1741 cggggcgcgg ccgagccgcg gccgcagcag gaccacgacc gcgagcacga tcgcgccgag
     1801 gcagcgcagc ggggtgttgc cggtgacgag cagccagaga ccccaggaga acagggaggc
     1861 ggtggcgagg tggacgacgg tggcgatggc ggacgcggcc agccagtccc gccgcccggc
     1921 ggtggccgta cggccggccg cgacgtcctc gtagagccgg tcggtccggg cggctgcggc
     1981 cgcctcatgc cgggtggccg cggcgcgttc cggtcccggg gtgaggttcc agtcgcagtg
     2041 cgggcaccag gcggtgaacc gcgggtcggc gtccagcgcg gcggcgcagc gcgggcaggt
     2101 ctgcggggcg gtggccgggg cctgggccgc ggcaggggcc gcggcggggg cgggcacggc
     2161 aggagtgggc acggggggag tgggcacggc ggacgatcat gccagcgggg gcccttcgcc
     2221 ggtaccccga ttcccggcgg gcccgttccg tcctcgtccg ggccgggccc caccggtgaa
     2281 acgtgttcta ctccgggcgg gcgaggcgtg ccagaatcgg cccgaccacc gatccgaggg
     2341 gaatccggga gcagccccat gcgcgcagcc atcctgcaca agaccggcca ggacacgctc
     2401 gacgtccgcg acgacgtggt ggcggtcggc ttcggccccg gcaaggtgag agtccgcctg
     2461 cgggcggcca gcctctgtca ctccgacctc tcggcgatga gcggcgtcct gccgcagccc
     2521 gcgccgttcg tccccggcca cgagggagcc ggtgacgtgg tggaggtcgg cgagggcgtg
     2581 accggcgtcg cggcgggcga ccgggtggtg ctctgctgga tggcgccctg cggtcgctgc
     2641 gcccactgcg agcggggccg cgggcacctc tgcgtctcca gcctgcgccg gctcggcgcc
     2701 ccgggcttcc ggttcgacgg cggcggtgcc ccggtcgacg cctccggctt ctacggcacc
     2761 ggtgcgttcg ccgaggaggt ggtggtcgag cgcgacgccg tgatcaaggt cccggccgac
     2821 ctgccgtacg agctggccgc cctgatcggc tgcggggtga ccaccggcat cggtgccgcc
     2881 gtccacaccg cgcaggtcga gccgggctcc tccgtcgcgg tcatcggcgc gggcggggtg
     2941 ggcgtcgcga ccgtgcaggg ggcccgggtc tgtggcgcgg gccggatcgc cgtggtcgac
     3001 ccggtcgtgt cgaggcggga gcgggcgctg gccttcgggg ccaccgacgc gctcgccccg
     3061 gaggagctga aggccgtcgc gaagggcctg ccgggcggcg gcttcgacta cgtcttcgag
     3121 gcggtcggcc gcgcggccac cgtccgggcc gggtacgacg cggcgaggcg cgggggcgcg
     3181 gtggtggtga tcggcgccgg ggcgcaggac gacctcgcgc agttcaccat gggcgagctg
     3241 ttcttcaacg agaagcgcct gctgccctcg ctgtacggcg ggacgtcggt gccccgcacc
     3301 atcgcgctgg tggtggacct ctggcgggcc gggcggatcg acctcgcggg gatgatcacg
     3361 caccgggtcg ggctggcgga cgtcaacgag gccgtcgcgc agatgcgggg cggcgaggcg
     3421 ctgcggacgg tcgtgacgct ggactgagct ccggccgccg gaacgcggca gggcccgccg
     3481 gtcgcacgat gtgtctcgac cggcgggccc tgccgcgcac tgcgggagcg ggctcagccc
     3541 tggtcggccc cggcaccgag ccggtgccgg ccgtgcgggt cggcctcggg gctgtcgtcg
     3601 gcggcggtgc ggccgcggtg gcggccgtgc gacgcggtgt cctcggccgt ggtctcgtcg
     3661 gcgtcggtcc cgttgaccgc gggtccggtg gtgtcggtga gggtgtcgga catcagaatc
     3721 gtcttccgtg cgagggtgca ggtgtgtcgg cgcccgtcgg gcgccgcggg cggcgggcgg
     3781 acgtgtggcc ggcatgaccg ggcgcgcgaa cagcgccgga gccggtgatc acggcccgcg
     3841 ccccggccac cataacggcc ggaacgggcg agatcctatc gagatcacgt cgggcggccc
     3901 acgaacgacg cggcgccgcg ctgcccggcc gatcccaacc agtggcccac cagttcgcgg
     3961 tagagcggcg acagcacctg gagatcgccg tgccgtgcga gcacgccgcg gccgccgtcc
     4021 agcagcagga cgcggtcggc ccggagcgcc gaactgatcc ggtgcgccac cacgaccagg
     4081 atcccggggc gggcggcgaa ggcgcgctcg acccggtcct cggcggtggc gtccaggtgg
     4141 caggtcgcct cgtccagcac cacgacgggc gcgggggaga ggtaggtcct caccagtgcc
     4201 aggagttggc gctcaccggc cgagagcgcg cccgggtcgg cgagctcggc atcggggccg
     4261 ccgagccggg cgaccagacc gtccgcaccc aggagggctg tggcgtgggc gagttgggca
     4321 tcggagggtc gggctccggc gggtggggcg ggccagcaga ggttggcgcg caccgtaccc
     4381 gggaacacgt acgcctcctg cgggagcagc gccaccaggc gggaccgttc ggggccgggg
     4441 aggaggtgcg ggcggacgcc gcccacgccg acctcgccgt cgagcggggc gagcaggccg
     4501 gcgagcagcg cggcgagggt ggacttcccc gttccgctcg ggccgaccac ggccaggtgc
     4561 tcgcccgggg ccaacgccac gtcgaggccg gagaagaccg gttcggcggc cgggccgtgg
     4621 gcgtagcgga gggcggtgag acggaggccg acggccgtgg gcgggggcgg gggcgggggt
     4681 gccgggggta ccgggggcgc cggggaggag gggtcagcgg gtgcggggcg gggttccggc
     4741 tcgccggacg tggtggcgag ccggtcgagg acgacggcca ggctcagcag ccacccgccg
     4801 accgttccgg ccagggtcct caccgcgggg tcgagttgct ggagcagata ggtggccacg
     4861 ccgagcagtt cgccgggcgt gaggccgccg tcgccgagca gccagggcga tgccgcgacc
     4921 accgccagca ccggcaggcg gccgccgagc gcgaccacca gcgaacggag cgccgcggcc
     4981 cggccgagcg cgcgggacgc tgcggcgctg ttcccggcgg tggcggcgag ggcctcggcc
     5041 gtcctgtcgc gggagccggt ggcctggatg tcgcgcaggc cgtggagggc gcgtccggcc
     5101 tcggcggcca ggcgctcctc ggcgagcacc acggcgcgtc ggcgctccac cagcggacgg
     5161 agcagccggg cgaacagcag gccggcggcg agcagcggga cgagcaccag cggcagaacg
     5221 gccggcgcga gcagggcgag gcccgccagg gcggcggcca gggtcacccc gaccccacgc
     5281 agcgtgcgga gcagggtggc ggtcaactgc cgcgcggact ccacctgttc ggtcagccgg
     5341 gcgacctcgg ccggatcggc gtgcggccgg gcgagcgcac cccggacgac ccgctccacc
     5401 agggcgtcgc gcaacggctc gaccacggcc gcgaggtacg ggaacccggc ccgtgccgcg
     5461 tacgcacggg cggcggtcac caccccgaag ccggccagcc aggccacccc gacccccggc
     5521 cgcccggcca ggaacccccg gtccacggcg gccgacacca tcagccccga ggtcagcgcg
     5581 ggcagtgcct ccaccccgga ccacccgagc agccgccaca gcgccccgcg ggtggtcgcg
     5641 agctgccggc cgagcagcgc ccagccgggt gggcgtcgcc gccccggatc tcccgcgtcc
     5701 ggtacgccgt ggccgtagcc gccgccggtg tggtggccgg tgcccaggac ggcgctgtgg
     5761 ccgtggccgt ggccgtcgcg atggccgtcg cggcggccgg tgccctggga cgcgccgtgg
     5821 ccggcactgt gacggcccat caggcggtgg ccgcttcgag ggcggtgccg gagagggtgg
     5881 cccggtagtc ggggtcggcg aggagctcgg cgtgcggggc gagggcgcgg agccggccga
     5941 cgtcgagcca ggcgaccagg tccgcgcggg cggcggccga ctcgcggtgt gcgaccacca
     6001 gccgggtgct cccgtgggtg gcccggtcca gggcctcggt gatctggtac tcggtggcga
     6061 ggtcgagccc cgaggtggcg tcgtccagca ccagaacccg ggccggccgg gccagcagcc
     6121 ttgccagtcc gaggcgttgc aactcgccgc cggagagccg gagctcgtcc agcggggtgt
     6181 cccagccggc gggcagccgc cgcaggaagc cgtccgcccg ggccgcggcc acagccgcgg
     6241 ggccggcgcc gtccagcgcg tcgcggaccg tccggccggt cagcgcaggg cgttcgaagg
     6301 cgtagccgac ggcacgccgc agttcggggg cggccaactc cccgacgggg acgccgtcga
     6361 cgagaacccg cccctcgtcg gggtcgcgca gccggccggg cagggcggcc agcagggact
     6421 tgccgcagcc ggaacggccg accagggcga cggtgcaccc gcccgggacg gtcaggtcga
     6481 gcggcccgag cagcacccgg tcgccgtcgc gcaccaccac gccccggaag gcgagttcgc
     6541 ccgcgccgcc ctccggcagg acggccgcgc cgccggtggc cggtgcgagc gccagcagtt
     6601 cgtccacccg gacctgcccg gcccgtgcgt gcgccacccc gaccaacgcc tcgacctgct
     6661 cgaacagtcc ggccccgagc gccgcccagc cggccgccgc cgcgagggcg ccgggcgcca
     6721 gcgtgcccgc cgccaccagg gcgccggccg tggcaagcac cgccacctcg accacggcga
     6781 tcagcagcgt cgcctgccac gccgtccgcc gctgcgccgc ccagagcgcg tgcccggccg
     6841 ccgagagcgc gggcagcggc tccagcacgc gcgcctcctc gctccgctgg gccccggccg
     6901 cgtggatgct gcgcagcccc gtgagcgctc cggtcagccg ggcggcgagg tcggcctgca
     6961 cctcctggta gcggacgaag acctgcccgg cctcccgcag gaagagccgg atcagcacca
     7021 ccccgggcac cacgccgccg aagaaggcga gcgccagcca cggcgagagc accccgagcc
     7081 cgacgatcgc gccggccgag gtgagcagtg cggtggcggc gccgagcacg gcgggcagcc
     7141 ggccgccggc gtcggccgcg gagccgacca gccgggcggc caggtcgccg ggcggcgggc
     7201 cgtcgcgcca caggcggccg ccggggccga gggcgagcag gtggcggacc agccgcccgc
     7261 gcaggccggc ggtggcctcg gccgcgcagg cggggccggc cgcggcggcg agcgcgttgg
     7321 cggcggcggc cgtgccgacg acgagggcga gcagggcgga cgcgcagtgc ccggcgtccc
     7381 ggtcgagcgc ggcgtcgacg gccccggcga gggccggggg cagggcgagc gtggtggcgg
     7441 cctcggcggg cagggcgacg gccagcgcga gggtccagcc ggtggggcgg cggggcatgg
     7501 gcggactccc gtcggggcgg gtggaggaag aagggggaag cgggtggagg aagggggaaa
     7561 gggacggcgc cgctcccgcc tgtccggaca ggcgggagcg gcgcccgtgg gccaccgcgt
     7621 cagagggtgg ccgaccgccg tacgactagc tgatcgtgaa gatcaggcag gtcaggatga
     7681 gacaggtgta ctggcagccg ccgccgtggc cggtcagctc gacggactcg gtctcgggca
     7741 gctcctgcag ggccgcgagg tcggtctcga agtccaccat gttctccatg atctgggtcc
     7801 tcccctggtg tttccgcccg tcgcgatctg cggtgcgggc gatcggtggt gctcccgcgg
     7861 tggcctccat ccaccgccgc gggtaccaac ccgggccatc ggggcccggg agtctgtgag
     7921 gccggccggg gcgtcgggcc cggccggccg gccggtcacc ccggacggcc ggtccgcagg
     7981 aaggcggcca gcagctcgtg cagcacggcg gcaccgtcct ccgccagcac ctcgtgcccg
     8041 gcgccggccg cctccacgta ccggaagtcg gcgccctcgg agcggccgat ccgcagcagt
     8101 tcgtgccgca gtgaacggga ctggctcacc gggacgacct cgtcccggtc gccgtgcacg
     8161 accaggagcg gcgcgttgag ccggtgcgcc agctggagca cgtcgcgcgg gccgcgggcg
     8221 tccgcgatcg gctcgccgcc gcccagccgg gtcgtcaacg ccctcaccgg ggaagccgct
     8281 tcggacagca gacgggcacc ggacaggaac ggcgcgacca ccgcgcagcg tgcgacctgt
     8341 tcggcgggcg cgtgcgccgc ggccagcagg gccaggaacg cgccgtagct gacgccgaac
     8401 agggcgggcg gctccaggcc gagcgcggcg cgctggcccg cgaggccgtc cagcaggtac
     8461 aggacgtcgt cgaggtcggg gccgccccag gcgccccgga tggccatcgc gtgcgccacc
     8521 ccgtaaccgg tggaaccgcg ttggttgggg gcgacgacgg cgagcccctc ggccgccatc
     8581 cgctgcaggg cggggtcgaa ctccagccgc caggcgtccg ccgggccgcc gtgcagggcg
     8641 agcaccaggt gcgggctgct cagccaggcg tcgccgccgt acaccacggc ctccagcggc
     8701 cctgccggac cggcgagttc gatgctctgg gccgggtgcc agcggccgcc gtcgccgggc
     8761 ggcgtggagc cgtccagccg ccaaccggcg ggcgcggcag gggcggtgcg tgctccgccg
     8821 ggctgccagg gcaggacgac gtcccgccac ggcccgggga ggccggagcc cggcaggccg
     8881 gtgccgagcg gtgccaactg caggggcagc ggcgccggtc cgggcccggc ggaggccggg
     8941 ccgtgggcca gcagcgcgtc gacgtccagg gtggccagcg ccgtcggatg gtcgggggag
     9001 gagtacggca tccgcagccc cgcctccgac cagtggccgg ccgcgccgag ccgcccgggc
     9061 ggcaccggca gcgggtccag tcgtccggcg gcgggccgcc acagggccag cgccgagccc
     9121 gcgccgtggt cgatctggac caccacccgg accccctccg gcgcgggccg cagcgccacc
     9181 ggccgcagga gcatgccgga cacgtgcagg cactccggga accgcagggg cccgccgccg
     9241 cccagcaggc cccagccgag ccggtcggtg ccgggtgcgt cgctgcgcac catcgcgaag
     9301 cggctgtccg ggtcgaacag caccagccgg tcgttgctgc gttcgccgat ctccagcagt
     9361 ggggtgacgg tgccgctgcg caggtccagg acgacggtgc ggacgacgcc cgcgccgacc
     9421 cggtcgagtg ccagcagggc gccggcccgg tcgagccaga cgccgccgcc gtgcagcccg
     9481 gggatctcgg cgacctggcg gggctcgctc ccgtccgcgt gcaccagcca gacggtggtg
     9541 gccggccggg tgtcggtgcc cagcgccacg gcgaccggga cgcgtgcgcc gtccgctgtg
     9601 cgtgcgccgt ccgctgcggg tgagcccgcg gcggacgccg gaagcggcag caggcgcagg
     9661 ccgggccgtt tgaaggcggc cagccggcgt tcggtggtgg ccggttcaca gcccggcccg
     9721 gcggcgtcga gcgccaccag ttcgtgccgc tcaccgtcgt gccggcagac caggacggag
     9781 ccgtccggca acgcgatcag ctgcgagcgc aggttctcgg accggttgcc gggcagcgcg
     9841 agcggggtcg gtacggccgg gccggacgcc ggcaggtccc aactctccgc gtaccagccg
     9901 ccgtcggcgg cggacgcgag gcaggcggca tggctgccgt cggcggcgaa ggagaagctg
     9961 aggcggcgca gggcgtgcgt cgcgctcctg gtggccacgg tcatgtcgcc ctcgtttcgc
    10021 ctgcgggggg cggcagttcc ccggacggga ccggaggcac cgggtccacc cagagccggg
    10081 ggccgccgtg gcacagccgc agcaggaagg cgagcgggcc cgccgtcccg gtgccgtacg
    10141 cggcggaaca gccggtgccg gtctcgtcgg gaaggaccag tagtccgttg cgcagggcgg
    10201 acctggcggt gatcagctgc gccaactcct cggcgcccgc gcggaattcg gcgtctccgg
    10261 tgaacccggc caggtcgagc aggtattcgc cgttcccggc cagtccgtgg caggcgctga
    10321 cgccgcagtg ccagcgcccg gccagcacgg cccgtcccgc ggcgagggcg agttcacgcg
    10381 cggtggcatc gccggtgacc tgccagagcc ggagcaggaa ggtgcccgcg cccgaggcgc
    10441 cgctgcacca gtgggcgagc ctgacgtgct cggggtcgcc ggcgtcctgc ggccaccagg
    10501 cgctctcccg cgtgccgccg acggtctccc gccgcacggt gcgcgcgagt gtacgcccgg
    10561 cctcgacggc gccggcgagc agtgcctggt ccccggtggc ctcgccggcg gccagcagga
    10621 acgcgccgac gcccgccacc ccgtgggcga acccgaggtg ggtgatcccg gcgagcgccg
    10681 agtcgaagtc ctccggtacc ggccagaccg tgccgtacgg cgagggccgt gcggcggcca
    10741 gcaggccgtg cccgcaggcg gtggcccggg cgaggaactc ccgggcggcg cccgttcccg
    10801 ggtcctcggc cgcgaagcgc agctggaggt ggccggcgcc ggcggcgccg tggcagacgt
    10861 cggggttggg ccacttgacg gctatcccgc gggccagtcc ggcggcgcgt ccggcgaggg
    10921 cgtggtcgcc cagcgatccg gcggcgtcca gcagggccca ggcggtgccc gagcggccga
    10981 agtgcagccc cggcaggacg accggctcgg cggcgcaccg gcgctcgatc cactccaccg
    11041 cggtccgcgt cgtctcacgg gcctcgtccc gcactccggc cggcagcccg ccggtcacgg
    11101 ccgcccgggc gagcagtgcc agcaccccgg cggcgccgtg ctggacgttg caggggtcgg
    11161 accgctcccc ggccgggacg gcgggccaga gccggtcgcg ccgcagcggg gtggcggtgg
    11221 cggcgaggtg tcgcaggccg tcgtgcagca cccggtcgac gatcgtcccg ccgctccccg
    11281 tgggccgggt ttccacggcg ctcacctgcg gcccgccggc cgtgtccgtg cagctgtcgc
    11341 ccgatccgcc ggccgtgtcc gtgccgctgt cgcccgatcc gccggccgtc gtcgcgggcc
    11401 cgcccgtcag ggcctcccgt acgcggtgaa gccgccaccg ctgctccggg tcctccgcgc
    11461 gcagccccag taccaggggt gcgagccgcc gggccgtgtc gccgccgcgg gcggcgagcg
    11521 cgagccagcg gccgaggcgg tcggcgaccg ggcgggcgca cggcaggtcc tcgggcagca
    11581 gcgggtcgtg gccggtcgcg agcaggaaga agaggccgcc gagcgcatag aggtctgcgg
    11641 tcggctcggc tgcgcagacg ccgcccgcgc ccgtgccgcc cgcgccgccc gcgccgccct
    11701 cggccgggcc gccgtccgac ggcgcgccgt cgaccagggc gagccgcccc ggcccctgct
    11761 cgggggcacg gtagcccggg gtgccggccg agccggcgcg gcggcctgcc tcggcggcca
    11821 gctccaggtc caccagccgc agggtgccgt cgggctgcac caggacgttg ccgggggaga
    11881 ggtcgcggag caccaggccc agctcgtgca cccgctcgac caggtcgagc agggcgtgca
    11941 ccagcggtcc ggcctcggcc cagtcgacgt cggggctgcc gtcgcggcgc agccgggccg
    12001 cgacccagcc gcccagcggc tgcccggcga ttcgttcctg cacgaggaac agcgagtcgt
    12061 cctgctcgat cagttcgacc ggtcgcggtg ccagccccag gccctccagc cgggccagca
    12121 gtgcggcctc gtgccgcagc gcggcccggg cgtcggtgcc ggagcggtcc acctcgatgt
    12181 gcgcgcgggc ctgcttgacc acgacctccg cgccggcgtc ggtgtcccgg ccgaggaaga
    12241 cgccgccctt ggcgctgtgc cggatcgcgc cggtgatcac gtaccgcccg gccagcagca
    12301 cgccgccggc cccgcgccgg gccgcggccg gcttggccgc cccgggcccg cggcggtcgg
    12361 cgccggctcc ccggccctcg gccccccgcc cttccgccag cgggtcgcgc gcccacggcg
    12421 ggcaccggta cgtcgccccg cgcacgtcct cgaccagctc gccgtccggc ccgcgcagca
    12481 tcgaccggta gccgccgtcg ttgcccagct cggcacgggc cgcgaaggcg ccgtaccggt
    12541 agtggacgcg gctgccgggc cggtacggcc ggtcggagag cacgaccggg ccgggcaggc
    12601 cgtcggtggc ccggtgcagg gcggcggcga gccgccggaa ctgctcctcg ccctccgggt
    12661 agacggtgat gaacttccct gccgaacccc ggtcgctgtt gcgcgagttg agctcgtgca
    12721 gctgctccgg cccggcggcg aacttgaacg cgcacggatc gtcggccagc acctcggtga
    12781 cggcggcgag caccgcgccc cccacggcgg acgccgcgct gacgtggatc ttccagccct
    12841 ccccggccag ttctcccgcg gacggcctgg ccgtgcacca gaagccctcg gcggtgacct
    12901 cccagtcgcc gccgcctccc cggcccccgg cgccggccag cgccgtccgt gtgacctccg
    12961 gccacgagcc ggccgcagcc ggcccgtggc ccgccgatcc ccttcccccg gccgtgcgaa
    13021 gcgaggtgcc cgtccccatc cgctctcaca tcccttcgtc tcggccggcg cccgccggtg
    13081 cccactgctc cggcacccgg gcacacggcc acggcctgat cggtttctcg gaggtaacgg
    13141 gagtgccgcc ccggtcgcgt ccgccgcggc cctcggccgg ggtccggtcc ggaccccttc
    13201 ccgaggtgcg gtccgaaccc ctcccggggc cggtgcggac cccgcctgac cagggcccga
    13261 gctccggcgg agcaccttcc cgacccacac ggtcggggca actcccgttc gcagaagtga
    13321 agttactttc ggtttcgggg cggactcaac gcgtagcgag tcacttcact cgtaagggtg
    13381 atctgagcac tgtttcgaat tcgtgcgagc cgccccctgt gagcggcgag ccccgcgtgc
    13441 cccggcggac ggggcgcccg aacggcccgt acgccgtctc cgcccgcgcc ccgggcgccg
    13501 tccgaacgcg ctgaaccgca ggttgacgcg cacctgtgcg ccccgtcccc gcaccggaca
    13561 ccggccgtcc cccgagccgg gcaccccgcc ttcccggcgg gccgggcggc ccgggcgccc
    13621 ccgcgcgcac ggtagtctcg acaggtgccg aaactgtccg aggtcattgc cgcgctcgaa
    13681 gaggtctacc cgccccagtg ggcggagtcc tgggacgccg tcggcctggt ctgcggggac
    13741 cctcaggccg aggtcggacg cgtgctcttc gccgtcgacc ccgtgcaggc ggtcgtcgac
    13801 gaggccgtcg agtggggtgc cgacctggtg gtcacccacc accccctcta tctgcgcggc
    13861 accaccagcg tcgccgcgac caccttcaag ggccgggtcg tgcacacgct gatccagagc
    13921 ggcatcgccc tgcacgtggc gcacaccaac gccgaccacg ccgacccggg cgtctccgac
    13981 gcgctggccg aggcggtcgg cgtccgcgtg accggtccgc tggtgccgga cccgaccgac
    14041 ccgctgggcc ggcgcggcgc cggccggatc ggcctgctgg agcccccgct cacgctctcc
    14101 gtcttcgccg cccaggtcgc caggggcctg ccggccaccg ccgccggcgt ccgggtctcc
    14161 ggcgacccga accggctgat cagccgcgtc gcggtgtgcg gcggttcggg cgacagcatg
    14221 ttcgccgagg tgcgggcggc cggcgtcgac gcctacctca ccgccgacct gcgccaccac
    14281 ccggcgtccg aggccgccga ggcggcgccg gtcgcgctgg tcgacgcggc gcactgggcc
    14341 accgagtggc cctggctcgc cctggccgag cgggcgctgc acggtgccgc cgagaagcgg
    14401 ggctgggccg tggagaccaa ggtctcccac aaggtcaccg acccgtggac cgcgcacgcc
    14461 tccatgtcct tcaccgcctg acccgattca caggagctct ccgcttgaac gccgcgcccg
    14521 ccgaccagat ccgcctgctc gacctccagg ccatcgactc gaagctcgac cagctggccc
    14581 accggcgtcg cagcctgccc gagcacgccg agatcgagaa ggccaccgcc gaccacaccg
    14641 cgctgaagga cctggtcgtc gccgcccagg cccagcaggg cgacaccacc cgcgagctga
    14701 ccaaggccga gcaggacgtc gagcaggtcc gcgcccgctc cgcccgcaac cagcagcgcc
    14761 tggactccgg cgcgatcacc tcgccgaagg acctggagaa cctccagcac gagatcggct
    14821 cgctcgccaa gcgccagggc gacctcgagg aggtcgtgct ggagatcatg gagcggctgg
    14881 agtcggccca gacccgggtc accgagctga ccgcgcgtct ggagcactcc tcggtcgtgc
    14941 tcaaggaggc cgaggcccgc cgcgacgccg ccttcgccga gatcgacggc gaggccgacc
    15001 gggtccgccg cgagcgcgag accgtcgccg tcgtcatccc ggccgacctg ctgaagctct
    15061 acacccgtct gcgcgagcag cagggcggcg tcggcgcggc ccgcctgttc cagcgccgct
    15121 gcgagggctg ccgggtcgag ttcgcagtct ccgacctgaa cgccatcaag gccgagccca
    15181 aggacgcggt cgtccgctgc gacaactgcg gccgcatcct ggtgcgcacc gcggaatcgg
    15241 gcatctgagc cggtggcggg gcgcaggttc atcgtcgagg cggacggcgg ctcccggggc
    15301 aacccggggc cggccggcta cggtgcggtg gtccgggacg gcgacaccgg tcagatcatc
    15361 gccgaggccg ccgagttcat cggccacgcc accaacaacg tggccgagta caagggcctg
    15421 atcgccggcc tgaaggcggc ccgggagatc gacccggacg cctcggtgga cgtccggatg
    15481 gactccaagc tggtggtcga gcagatgtcc gggcgctgga agatcaagca ccccgacatg
    15541 cagccgctcg ccgccgaggc ccgtggcgtc ctcccgcgcg gccaggtcaa gtacacctgg
    15601 atcccgcgcg agcggaacaa ggacgccgac cggctcgcca acgaggcgat ggacgcgggc
    15661 aaggccggcc gccagtggga gcccaagccg ctgaaggccg cgtcgcccgt cgtcgtggag
    15721 ccggccgccg agccgccgct ggagaaggcg gtgccgaagg ccggctgggc ggccgccgcc
    15781 gacctcggga cgccgaccac cttcgtgctg ctgcgccacg gcgagaccca cctcaccccg
    15841 gagaagcgct tctccggcag cggcggcagc gacccggagc tctccgagaa gggccgctgg
    15901 caggccgagc gggccgccga ggcgctggcc gcgcgcggct ccgtccaggc cgtggtcagc
    15961 tcgccgatgc gccgcacccg ggagaccgcg gagatcgtcg ccgcccgcct gggactggag
    16021 gtccggtacg aggaggggct gcgcgaggtc gacttcggcg cctgggaggg cctcaccttc
    16081 gccgaggtcc agcagcacta cccggacgac ctcaacgcct ggctcggctc gcccagggcc
    16141 aagccgaccg gcagcggcga gagcttcacc accctcaccc accgggccgg ggtcgcccgc
    16201 gacaagatcc tcgcccgcca cccggggaag accgtgctgg tcgtctcgca cgtcagcccg
    16261 atcaagacgc tggtccggct cgccctcggc gccccgccgg actcgctcta ccggatggag
    16321 ctgtccgccg cctcgctctg cgccgtccag tactacgcgg acggcaacgc ctcggtgcgg
    16381 ctgctcaacg acaccgggca cctgcgctga ccctgccgac gcaacggcgg cgggctcccc
    16441 acggagcccg ccgccgttcg cacaccggaa ccccgccggt cagtggatct cggtgaccac
    16501 cacgtccagc tgccacggct tgcgcgcggt gccctcggcc gcgacctcca cccggtggcc
    16561 cagcccgagc agcgcgtcca ccagctcacc gggcgtcttc ggctcggcgc ccgccaccag
    16621 caggtcgcgc accagccggc ccttggtcgc cttgttgaag tggctcacca ccgtgcgcct
    16681 gccgttccgc tcctggagca cctgcacggt cgccgtccgg gacaccacct cgccggccgg
    16741 cttccacgcc gccgcgtacg ccgagctgcg caggtccagg accagcccgt ccgccacctc
    16801 cggcagcacg gacgccgtcg cgccccgcca gtacgcgccg agcgcccccg gcccggggag
    16861 tttcacgccc atcgagcagc ggtagggcgg aatccggtcg ccgatccgca ccgcacccca
    16921 gagccccgag aagaccagca gcgaacgcgc ggcccggtcg tacgccgcct cgtccagcgt
    16981 ggccagcccg aggttgtcga acagcacccc ggtgtacacc tcaccggccg gcagcgcgcc
    17041 cgccgtcggc agcgcggcgt tgcgcgcgat ctcgccgcgc aggccggggc tcagcccgag
    17101 cacctcggcg gccgtgtcct cgtccccccg gcagagcccg accagcgcct ccaggacctg
    17161 ctcccgcgcc gccgtcagcc cgggcagcga cagcccgtcc agtgccaccg gcaccccgtc
    17221 cccggacgcg gccttgccct ccgagggcgg caacagcacc agcacagcgg actcctcaac
    17281 agtttgtggc ggacgatccc cgccacccta cgcaaaacca ccccgccccc ggagacccgg
    17341 tccggccggt gaacggccgg gggcctactc cccgcgccga gccccgccgg ccaccgcgac
    17401 cacggcggcc ccggtgccga gagccaggca gagcggcgag tagtaccggg tgtccagtcg
    17461 ccggaaccgc tccgagcgcg ccaccaagcc cccgccgaac atcgccagcc cgcccgcgcc
    17521 ccgtgccagc atcaccccgg cgaccgcccg gaccccctgt cgccgcaccc atgccggccc
    17581 ggccttgggc agcacgccgg cctccgcgcc caccaggtac gccgccgaac cgagcagccc
    17641 cgccaccgcc acgcacgcgg ccgccggcgg caccccgtca ccggtgccga ccaccgtgtc
    17701 cgcgaactcc tccggcgtcc gcaacggcca cggcgtcacc gcccacaccg cgtgcagcgc
    17761 ccccgtcgcc gccagcaccc cggccaccgc cgccccgcga ccttcaccgc gcccatcgcc
    17821 gaaccccctc cgcagaacac cggttcatgt cccgaccacg ctacggcccc cttacgcgtc
    17881 ccggcccacc gccgtggccg tcggcgtcgc cgcgcccgcc gcgcccgccg tgtccccgaa
    17941 aaagcgctgg tcaccgcggt ccggtacctc taccgtcgac gtgacgagga gtgtgacgcg
    18001 atgaccctgc gacccctgga cctggtcccc ggcgacgacg acgccgtgga ggagtccctg
    18061 cccgtccgcc tgcccgccgg ccttccggcc gagaccaggc aggcgctgga gttcgcactg
    18121 gaggcggccg cgcaggcggt gctggccggc cgggtgcggg tcaccggggc accggacgag
    18181 gacgaccgcg ccgagctggc cttcgacgtg cgccagtccg agctccccga cgccctggcc
    18241 gagcccgccc gggccgccgc cgagcccggc cgcgccgagc gccgcgccgc catggtggcc
    18301 cggatccgcg aggccaacgc ggagacgctg gagaggctga aggacctgtg aacgcgacgg
    18361 ggggaacgaa cgacgtcgag tacctcgacc tggaggacgt cacctacctc gccggcggcc
    18421 cggagaacat acgcgacctc ggcgcgctgc tctccgcgct gggccgcccg caggcgagcc
    18481 tgttcggcgg ggacgcctac cctgacctct ggaccaaggc cgccgcgctc ggccagagcc
    18541 tcgcccgcaa ccacccgctg atcgaccgga acaagcgcac cgccttcgag gcgatgctgc
    18601 tcttcctcga ctacaacgac gagccctacg gcgacccgca cccggacgat gcggtcgcct
    18661 tcatgctccg cctggccacc ggcggctacg acgagtccgt cgccctcgcg gccaaggacc
    18721 tcaggtccct cctgggccgc tgagcactcc cggagcgcgg cccggccacc ggcgcgcccg
    18781 gtggccgggt ccgtctgcaa tcacccgatt cgccctacgc tgcctccatg ccacgccgaa
    18841 aactgcgcgt caaggccgcc gactccgccc ggatcaacgc cgaactgacc gagctgcgcg
    18901 cccgcctgga gatccacacc gagtggcccg acccggtcct cgcggaggcg gaggaggccg
    18961 cccgcacgcc ccggctgccg gagtacgacg cgaccgggct gccgctcctc accgtcgacc
    19021 cgcccggctc ccgggacctc gaccaggcca tgcacctggc ccaccgcccg ggcggcggct
    19081 accgggtgca ctacgcgatc gccgacgtcg ccgccttcgt ccggcccggc gggctgatcg
    19141 acgccgaggc ccggcgccgc gtccagaccc tctacttccc ggaccaccgc gtcccgctgc
    19201 acccggcccg gctctccgag gacgcggcca gcctgctgcc gggcgagacc cgccccgccc
    19261 tgctctggca gctcgacctg gacgcggacg gcgccgtcgt cctcgccgac ctgcggcgtg
    19321 ccctcgtccg ctcgcaccgc cggctcgact acgccgccgt ccagcgcgcc gtcgacgcgg
    19381 gcggcgccga cgagcagccc gccctcctcg ccaccgtcgg ccggctgcgc gaggaacagg
    19441 aacgggcccg aggcgggatc agcctgcccg tccccgagca ggagatcgag gagaccctgc
    19501 acggctacgt cctcggctac cgcgcacccg cccccgccga cggctggaac gcccagatct
    19561 cgctgctcac cggcatggcc gcagccgagc tgatgctgga cgccggcgtc ggactgctgc
    19621 gcaccctgcc cgccgccccg ccggaggcgt accagcgact gcgccgcacc gcccgcgcgc
    19681 tggacgtcga ctggcccgac ggcctgccgt acccggagct ggtccgctcg ctggacccgg
    19741 acgtcccgct gaacgcggcg ttcctcaacg agtgcaccgg tttgctgcgc ggcgccgggt
    19801 accacgcctt cgacacggcg cagggcctgc ccgtcccggc ggatccggcg cacgccgcgc
    19861 tggccgcacc gtacgcgcac tgcaccgcgc cgctgcgccg gctgggcgac cgcttcgccc
    19921 aggaggtctg cgcggccgtc gccgccggcg agtcggtgcc cgactgggcc cgggaggcgc
    19981 tgcccgccgt gccgtccctg atggcgggcg gggaccgccg ctcggccgag gtcgagcggg
    20041 cctgcgtgga cctggtggag gccgagctgc tggcgggccg ggagggggag gacttcccgg
    20101 cgctggtgat cgacgtggac gagcagcggc ccgcccgcgg caccgtccaa ctgcgcgagc
    20161 cggccgtccg ggcccgctgc gaacgccccg acgacgcgtc gggggccggc cgcggcctgc
    20221 cgctcggcgg ggaggtcctc gcgcggctga cggtcgccga cccggccacc cggacggtcc
    20281 gcttcaccgc cgtctgaccc cgcccccggt gggaggatcg tcccgtggcc gaaccgaacc
    20341 cccgcaggac gcccccgggc gagcaccccg gcacgccgtc cgccccgccg tccgccccgc
    20401 cgtccgcccc gcccggccgg cgccgccggc tgctggtcct ggcgatctgc tgcctgagcc
    20461 tgttcatcgt cgggctcgac aacacggtgg tgaacatcgc cctcccggcg atccagaagg
    20521 acctcgacgc ccccgcctcc ggactgcagt ggatcatcga cgcctacacc ctggtgctgg
    20581 cctcgctgct gatgctgttc ggctcggtgg ccgaccgctt cggccggcgc cgggtgttcc
    20641 agaccggcct gctgctcttc gtgctcggct cgctgctctg cagcctggca cccagcctgg
    20701 agtggctggt ggtgttccgc gcggtgcagg cggtcggcgg ctcgatgctc aacccggtgg
    20761 cgatgtcgat catcaccaac accttcaccg agccgaggga acgggcccgg gcgatcggtg
    20821 tctggggcgg cgtggtcggc atctcgatgg cgctgggccc gctgctcggc ggcttcctgg
    20881 tggacggcgc cggctggccg tcgatcttcc tgatcaacgt cccggtcggc ctgctcgcct
    20941 gcgtgctgac cgcccggtac gtccccgagt cccgcgcgcc gcgggcccgc cggctggacc
    21001 cggtgggcca gctgctgatg gtggcactgc tcggctgcgg caccgccgcg atcatcgagg
    21061 gccccgaaca cggctggacg tccccgctga tcctggccct cgccgcgacc gcgctcgccg
    21121 cgctgacggc cttcccgttc tgggagcgca gggtcgccga accgctggtc gacccgcggt
    21181 tcttccgcag cgccccgttc accggtgcca ccgtgacggc ggtctgcgcc ttcgcggcgc
    21241 tcggcggctt cctcttcctc aacacgctct acctccagaa cgtccgccac tacagcccgg
    21301 tggaggcggg cctgtggacg ctgccgatgg ccgggatgat gctggtctgc gcgccggtct
    21361 ccggccggat cgtcggcagc cggggcccgc gcggcccgct ggtcgcggcc gggctcggcc
    21421 tcaccgccag cggcctgctg ctcacccggc tggccgcgga ctccccggcg gccctgctgc
    21481 tggccgccta cgcgctgttc ggcttcggct tcggcatggt gaacgcgccg atcaccaacg
    21541 ccgccgtctc gggcatgccg cgggcccagg ccggcgtggc ggcggcggtc gcctcgacca
    21601 gccgccaggt cgggcagtcg ctcggtgtcg cggtgatcgg caccgtggtc acctcggcgg
    21661 tggtcggccc gctcgtcacc ggcttcgccc cggccagcca cgccggctgg tggatcgtga
    21721 ccggcctcgg cgtcgccatc ctcctcctcg gcctggtcac cacgaccgcc tgggccaccg
    21781 gcaccgccgc ccgggtcgcc gcccgcctcg gcggcgaggc acccgtcgtc aggcccgccg
    21841 tacgggaggc cccgcccgag cggctaccat gaccactacg gcggaagagt cggccgggcg
    21901 gtcgcgacgg gtcctcaggg cccgccgagg aacgtccggg ctccacagag cagggtggtg
    21961 ggtaacgccc acccggggtg acccgcggga cagtgccaca gaaaacagac cgcccgcggc
    22021 ttcggcagcg ggtaagggtg aaacggtggt gtaagagacc accagcgacc ggggtgaccc
    22081 ggccggctag gtaaacccca cctggagcaa ggtcaagatc ggtgccctcg ggcgccgtgc
    22141 gcggatgacc gagggctgct cgcccgagtc cgcgggtaga ccgcacgagg ctgtcggcaa
    22201 cggcagccct agatggatgg ccgcctcccc gggccgcgca agcaccccgg gagacagaac
    22261 ccggcgtaca ggccgactct tccgtcctca ggcgtggtga aggcccgtcg gaccgctcag
    22321 cggtccggcg ggcctttcgc cgtccgtcct ccgacggggc actgcccgcg gctcaggccg
    22381 ggtgggcgcc gaccgcgtcg cggatctgtt cgccgaggcc gccgttgacg cgggcgcagt
    22441 tggcgcagca gaagaaccgg cccgccacct ccacgccgtg gcccacgatc cggacctggc
    22501 actgttcgca gcgcggcgcg agcttctcca tcgcgcactc gaagctgtcg aaggtgtaca
    22561 cgtcgccggt gatggtcttg atctcgaagg cgagccagta gtcgttgccg caggtgacac
    22621 agatggccat ggtggccgtc tcccttccgg tgggggctga acggccggtc gggcgctcag
    22681 cccttcccag tgtcggagcg gcccccggca ccggccactc ggccgcaccc gcccggaagc
    22741 atcgggggtc cggacggacc gggaggcccg tacgcaccgg ggagccggaa gcaccggcgg
    22801 ctcagccgga ccgggacgac agctcctcca gtgcccggac cgcccggtcg gcctcttcgg
    22861 cgccgacgaa caggtggtcg tggtggaagc cggccaccac gttgcagctg atcccctcct
    22921 cggccagccg gcccgccacg gcggcggtca ggccgacggc ctccagcgcc gagtggatct
    22981 tcagcgtgat ccaggccgcc acgtactcgt agcgcaggcc gagtgcgtcc gcctcctcc
//
