LOCUS       NZ_CP026498            49501 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. CB01881 chromosome.
ACCESSION   NZ_CP026498
VERSION     NZ_CP026498.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CB01881
  ORGANISM  Streptomyces sp. CB01881
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     A 3-hydroxy-3-methylglutaryl-CoA synthase gene based probe for the
            discovery of the acyltransferase-less polyketide synthases
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2018) Xiangya International Academy of
            Translational Medicine, Tongzipo, Changsha, Hunan 410000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002953255.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 02:39:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,978
            CDSs (total)                      :: 7,904
            Genes (coding)                    :: 7,565
            CDSs (with protein)               :: 7,565
            Genes (RNA)                       :: 74
            rRNAs                             :: 5 (5S)
            complete rRNAs                    :: 5 (5S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 339
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 339
            Pseudo Genes (frameshifted)       :: 124 of 339
            Pseudo Genes (incomplete)         :: 251 of 339
            Pseudo Genes (internal stop)      :: 10 of 339
            Pseudo Genes (multiple problems)  :: 45 of 339
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:44:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7138197
            Orig. end                         :: 7187698
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026498.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..49501
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="25"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..49501
                     /SMILES="C([*])C(-O)NC(CCCN)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..49501
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:29501](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..29501
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..49501
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:29501](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      20001..29501
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     misc_feature    complement(399..412)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.39"
                     /tool="antismash"
     gene            443..904
                     /locus_tag="C2142_RS21075"
                     /old_locus_tag="C2142_21115"
     CDS             443..904
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023580.4"
                     /locus_tag="C2142_RS21075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21115"
                     /product="DUF3592 domain-containing protein"
                     /protein_id="WP_148644095.1"
                     /transl_table=11
                     /translation="METTTATVGGAVLALFGGVLLLWCAAEVRLRHGVRRRGIPAVATV
                     VAESDTHSELDSSPLLTFSAPAAIDGPGAARRAEVVLARPRGHTPLRRPPRFSPGTSVR
                     ISYDPRRPSRVVLAAAETGGVVVTDLLWTALGVGCLAAGAALLAAAATN"
     gene            1439..4306
                     /gene="topA"
                     /locus_tag="C2142_RS21080"
                     /old_locus_tag="C2142_21120"
     CDS             1439..4306
                     /EC_number="5.6.2.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="topA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019762455.1"
                     /locus_tag="C2142_RS21080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21120"
                     /product="type I DNA topoisomerase"
                     /protein_id="WP_148644096.1"
                     /transl_table=11
                     /translation="MSPSSETAHGQRLVIVESPAKAKTIKGYLGPGYIVEASVGHIRDL
                     PSTAAEVPDKYTGEVRRLGVDVDHDFAPIYVVNADKKSQVSKLKSLLAESDELFLATDE
                     DREGEAIAWHLQQVLKPKVPVHRMVFHEITKSAIQEAVANPRELNQRLVDAQETRRILD
                     RLYGFEVSPVLWKKVMPKLSAGRVQSVATRLVVERERERMAFRSASYWDLVGTFGTGRS
                     PADAANPETFGARLSAVDGKRIASGRDFGSDGRLKAGSTNTLHLDEQAARALAAALEQT
                     AFSVRSVESKPYRRSPYAPFRTTTLQQEASRKLGFGAKRTMQVAQKLYENGFITYMRTD
                     STTLSDTAIAAARAQVTQLYGADYLPDAPRTYASKVKNAQEAHEAVRPSGDRFRTPAET
                     GLSGDDFRLYELIWMRTVASQMKDAVGQSVTVKVGGRAADGRDAEFSASGKIITFHGFL
                     KAYVEGADDPNAELDDRERRLPQVAEGDPLAADQLTPEGHATKPPARYTEASLVKELED
                     REIGRPSTYASIIDTIIGRRYVFKKGTALVPSFLSFAVVNLLEKHFGRLVDYDFTAKME
                     DDLDRIAAGEAKSVPWLKRFYFGEGEGHATGGAAEAGNGDGDHLGGLKELVTDLGAIDA
                     REISSFRISDDITLRVGRYGPYVERASAVEGEPGQRADIPDDLPPDELTVELAEELLAR
                     PSGDFELGQDPVSGNQLVAKDGRYGPYVTEILPEGTPKTGKNAVKPRTASLLKTMSLDT
                     VTLEDALKLLSLPRVVGTDPEGVEITAQNGRYGPYLKKGTDSRSLTSEEQMFTVTLEEA
                     LAIYAQPKQRGRAAAAPPLKELGTDPVSERPVVVKDGRFGPYVTDGETNATLRKDDEVE
                     TITPERGYELLAEKRARGPVKKAAKKAPAKKAAAKKTATKTAAKKTATAKTATAKKTTT
                     ATTATAKKTAAKKTAASKTTATDEG"
     gene            4590..7955
                     /gene="tmk"
                     /locus_tag="C2142_RS21085"
                     /old_locus_tag="C2142_21125"
     CDS             4590..7955
                     /EC_number="2.7.4.9"
                     /GO_function="GO:0004798 - thymidylate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /gene="tmk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947789.1"
                     /locus_tag="C2142_RS21085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21125"
                     /product="dTMP kinase"
                     /protein_id="WP_148644097.1"
                     /transl_table=11
                     /translation="MTSEEQPTPSAAAAARAGTPDLPEVAPAGTPGERARALLRLRPYR
                     RLWTTQLIGGTADRLGLLVLLALTVIAAALGGQFGDLPRSLAFAVAAVFAVRLAATVLV
                     GAALLGPVHGLLSGKLDRRWTLFGADVLRVVLIGVAPWWIVWLGSGSGADARPSGAATY
                     LLLGTVFVTGAAERVWAIAKAAAVPALLPPANPYAPPAERRPSAANLDTVGTLDRRTGW
                     ATVPLAAVALVALTLVGNVFAAVASDWLRAHQTTFAALGAAALFAVSAVRVYQHELPGG
                     PASVVPHSPLRGLRAPTDATPGPALGKGRTGSAPYFTFAVAAAYASMAGVAALALLTAA
                     EHRAGPIGYGLLVLVAAGTPALGARLARVTLPALSRRRLLALALLAEGVALILAGLVLD
                     FVLVLLLTVLAGLAAGIVISAGRNLLAQEVEEARLPKVTEHLNAVLRAVVGAALIVVPL
                     IAAAYGNIEYGTVEPGSFTFIHGGAALAVATAGLLTLVLAAVVLLRTDDRRGTVPFGRD
                     LVDAVRGAAGPVPHRTTDTGFFIALEGGDGAGKSTQAQALAEWIRGKGHEVVLTREPGG
                     SPVGQRLRGLVLDVGNTGLSHRAEALIYAADRAEHVENVIRPALARGAVVITDRYMDSS
                     IAYQGAGRDLAATEVARISRWATGGLLPDLTVVLDVDPTRARERFTEALDRLESEPTEF
                     HQRVRSGFLALAAADPARYLVVDGSQQPASVTTAIRHRLDRELPLSEQEKAARAEQERL
                     AREEAERRAAEEARKKAEAEAAERKRQELLEQLRAEQAEKERLAKEEADRLAAEAARKA
                     EEEARRRAEEEARRRAEEEAKLRAAEEARLAAEAAERKRLADEAAAQAELQRQRELARE
                     EQRRRAEEALQRAEEARLAQAAALAAAAAAAESAADRVGRPVPGDAVTTELRMVKDVDD
                     ATQEISERDRRAAVRAAEEAGAGVSGVDATAKFPVVPAAAADETAKLPVVPAAAADETA
                     VLPRVPGTDRTEVLPRVGPAGPAPRAGQDQPVDGTRELPVVEEPEQAPEPRPRPSWAEE
                     TPMDDLPSLTDTLLGSRDEWARWEQPGPAGQGPQDPRLAYGGEAAGPAGPAEPEADAPD
                     DQGGKGKGRRWRRG"
     gene            8149..9360
                     /locus_tag="C2142_RS21090"
                     /old_locus_tag="C2142_21130"
     CDS             8149..9360
                     /EC_number="2.7.7.7"
                     /GO_component="GO:0009360 - DNA polymerase III complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018102166.1"
                     /locus_tag="C2142_RS21090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21130"
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="WP_148644098.1"
                     /transl_table=11
                     /translation="MAVWDDLVGQERVVEQLTAAARAAGATVAAGRGAAPEPGGNASLM
                     THAWLFTGPPGAGQTTAARAFAAALQCTSPDLALGGTPGCGFCDGCHTVLAGSHADVKY
                     VRTDGLSIGVGDMRDLVLRASSYPTGGRWSVILVDAAHRLTEAAANALLKGVEEPSPRT
                     VWMLCAPSVQDVLPTIRSRCRLLVLRQPAAEAVADMLVTRDGVDPETARLAALAGQGDI
                     ERSRRLAVDEEVRTRRAEVLRIPLEVADLGGCLAAAQRLVDTAKADAEALAETQDAKET
                     DDLKAVYGAAEGGKAPRGMAGAVKELEKRQKSRATRTRRETLGVALLDLLGFYRDVLAL
                     QLGSTGALANEDQRPALERVAQAGPPEGTLRRIEAVLACRQALDRNVDPLLAVEAMTVA
                     LRAG"
     gene            9620..10780
                     /locus_tag="C2142_RS21095"
                     /old_locus_tag="C2142_21135"
     CDS             9620..10780
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS21095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_21135"
                     /product="hypothetical protein"
                     /protein_id="WP_148644099.1"
                     /transl_table=11
                     /translation="MVRSLLVVPLLAAAGGGVWLARGALLRWRDLRAAETYELTGDQRP
                     MLLRAAGAMVCGVCVTALTLLTALGTFGVLGSSAPRSGSAEFGADSDAAAADGTDGEAA
                     ARQAAPPVAEAEAASATAVSATTPAAAPVASRFDSVGHPAGGELLQSAVLGPDGHPRNV
                     RVWLPAQYAKDPNARFPVVVMHAATPRKTADAEVPDVFEGLGSAVQTGKARPFILVAPE
                     APNGTAHPCELVAAAPQAIADDAALRTTIAATFRTLPPGPASWGTLGVEGGAPCAAAAA
                     LARPDLYGAAAAVSGRYDTAALALTGAEAPVGAAPKLLLAAAKADAAGLDAARKLQAAL
                     RAGTGAAARADVRISENVQDYTADRERLRLVRQAAQYLAETLAKVS"
     gene            10983..12632
                     /locus_tag="C2142_RS21100"
                     /old_locus_tag="C2142_21140"
     CDS             10983..12632
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (139-520). E-value:
                     3.3e-28. Score: 90.9. Matches aSDomain:
                     nrpspksdomains_C2142_RS21100_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491974.1"
                     /locus_tag="C2142_RS21100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21140"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_148644916.1"
                     /sec_met_domain="PF00561 (E-value: 4.8e-39, bitscore:
                     133.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAERGRRRPAVAAVLAAGLLVGGCSFSTSTPRASSSDTVAPGSP
                     SALGSPSATASAADARPGVTPLEPLPAAVPAALAPYYGQRLAWQPCDEGFECTTFTVPL
                     DYDHPAGGDLTLSAVRAPAVPAGSGTGAGSGRLGSLLLNPGGPGGSAVDYVEAVARTYD
                     GGVRARYDLVGVDPRGVGRSAPVTCLGGERMDAYSAADITPDDQAEIDALVAADKEFAE
                     GCRQRVGDRLGHLSTVETARDLDVLRALLGDEKLNYVGKSYGTFLGATYAGLFPTRTGR
                     IVLDGAMDPSLDAITGNRTQAGGFETAWAAFAQDCAKREDCPLGRTEQQAGEQLTALFK
                     AIDAQPLTTADGGRRLTEAQATTGVIQAMYADFLWPRLRTALADAKTGDGSGLLKLSDS
                     YYERGSDGSYPNLMFANMAVNCLDLPAPFTGPGDVQQAVADFERTSPRFGRDMAWMALT
                     CTYWPVKATGAAHTIRAAGAAPIVVVGTTRDPATPYAWAQSLAGQLESGRLLTYEGDGH
                     TAYGRHDACVDGAVNRYLLGGEPPEQGKRCGA"
     aSDomain        11400..12542
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS21100_Abhydrolase_1.1"
                     /evalue="3.30E-28"
                     /label="C2142_RS21100_Abhydrolase_1.1"
                     /locus_tag="C2142_RS21100"
                     /protein_end="520"
                     /protein_start="139"
                     /score="90.9"
                     /tool="antismash"
                     /translation="LLLNPGGPGGSAVDYVEAVARTYDGGVRARYDLVGVDPRGVGRSA
                     PVTCLGGERMDAYSAADITPDDQAEIDALVAADKEFAEGCRQRVGDRLGHLSTVETARD
                     LDVLRALLGDEKLNYVGKSYGTFLGATYAGLFPTRTGRIVLDGAMDPSLDAITGNRTQA
                     GGFETAWAAFAQDCAKREDCPLGRTEQQAGEQLTALFKAIDAQPLTTADGGRRLTEAQA
                     TTGVIQAMYADFLWPRLRTALADAKTGDGSGLLKLSDSYYERGSDGSYPNLMFANMAVN
                     CLDLPAPFTGPGDVQQAVADFERTSPRFGRDMAWMALTCTYWPVKATGAAHTIRAAGAA
                     PIVVVGTTRDPATPYAWAQSLAGQLESGRLLTYEGDGHTAY"
     tRNA            12775..12848
                     /anticodon=(pos:7151006..7151008,aa:Thr,seq:cgt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="C2142_RS21105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="C2142_21145"
                     /product="tRNA-Thr"
     gene            12775..12848
                     /locus_tag="C2142_RS21105"
                     /old_locus_tag="C2142_21145"
     misc_feature    12925..12941
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            13333..13620
                     /locus_tag="C2142_RS21110"
                     /old_locus_tag="C2142_21150"
     CDS             13333..13620
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153397.1"
                     /locus_tag="C2142_RS21110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21150"
                     /product="hypothetical protein"
                     /protein_id="WP_148644100.1"
                     /transl_table=11
                     /translation="MDANRVLEALEAGEFDGVSHTYQPYDGYGNQTHQVAMSVSGGTIE
                     VAKTTSGKFFDGKENTRYSKTSTDYLTGMDAVGFIAQRPYYFSQVRPDLF"
     assembly_gap    13731..15364
                     /estimated_length=1634
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <15365..15946
                     /locus_tag="C2142_RS21115"
                     /old_locus_tag="C2142_21155"
     CDS             <15365..15946
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612357.1"
                     /locus_tag="C2142_RS21115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21155"
                     /product="IS5 family transposase"
                     /protein_id="WP_148644917.1"
                     /transl_table=11
                     /translation="DGQDVSDDQEREERRRIRRRRKLRLKAALLGRSRGGQTSKIHCAG
                     DRKCRPLAFILTEGQAADSPQFIPVLKKVRVRVPVGRPRTRPDAVAGDKAYSSRGNRAH
                     LRNRRIKAVIPEKKDQAANRKKKGSKGGRPVGHDAELYKQRNTVERLINKLKAWRGIAT
                     RFDKTPESYLAGLNLRASMIWIDDLLPTID"
     gene            complement(16160..16570)
                     /locus_tag="C2142_RS21120"
                     /old_locus_tag="C2142_21160"
     CDS             complement(16160..16570)
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018556825.1"
                     /locus_tag="C2142_RS21120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21160"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_148644101.1"
                     /transl_table=11
                     /translation="MLPASDGRPGVAAAIVTREGRVLMVRRRVSEGQLSWQFPAGKIEP
                     GESPEEAAVRETAEEAGLNVAAIKILGERVHPETGRWMSYTVCKIVSGTAAVGDPRELD
                     ALAWVALAEIPEYVPYGVFEPVQAYLDTALKD"
     gene            complement(16574..17125)
                     /locus_tag="C2142_RS21125"
                     /old_locus_tag="C2142_21165"
     CDS             complement(16574..17125)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018099974.1"
                     /locus_tag="C2142_RS21125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21165"
                     /product="flavoprotein"
                     /protein_id="WP_148644102.1"
                     /sec_met_domain="Flavoprotein (E-value: 9.7e-10, bitscore:
                     37.3, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEHREPFLYVVVCASGIADGVGELITAAHVEGWGVGVIATPSGL
                     GFIDQEAIEAQTGYPIRSAWRTPSIPQPLPPADAIAVAPATFNTINKWAAGISDTLALG
                     ILCDAYGLGIPVAVQPYVNSAQAAHPAYAESLARLRSMGVLIGDYVPHKPKAGGGRDKY
                     NWTHVLDLLRPVAASAAERK"
     gene            complement(17122..>18158)
                     /locus_tag="C2142_RS21130"
                     /old_locus_tag="C2142_21170"
                     /pseudo=""
     CDS             complement(17122..>18158)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073837.1"
                     /locus_tag="C2142_RS21130"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="C2142_21170"
                     /product="transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="ADSRTDDMHRRNFLAASVAALATPTPRPRVGIELVQALLPGPVPA
                     EHAPQPQAALAARLSQARRLFYTCRYAELEGALPSLIADLRQAQDAVRGGDQVLSGLLA
                     TAYQTAVSLLLKLGDHGNAWLAVGRAMAEAERSADPVVTASSVRVQAHVLARDRHTAPA
                     VTLIRHTADQLSAATTGARPSTSPRWGSCSFAG"
     misc_feature    complement(18756..18771)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.45"
                     /tool="antismash"
     misc_feature    complement(18771..18785)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.69"
                     /tool="antismash"
     misc_feature    complement(18794..18810)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.2"
                     /tool="antismash"
     misc_feature    18794..18810
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.67"
                     /tool="antismash"
     misc_feature    18795..18809
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    18799..18812
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.36"
                     /tool="antismash"
     misc_feature    complement(18799..18813)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.93"
                     /tool="antismash"
     misc_feature    18800..18813
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.58"
                     /tool="antismash"
     misc_feature    18800..18814
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.9"
                     /tool="antismash"
     misc_feature    complement(18801..18814)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.58"
                     /tool="antismash"
     misc_feature    18801..18815
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.25"
                     /tool="antismash"
     gene            18899..19777
                     /locus_tag="C2142_RS21135"
                     /old_locus_tag="C2142_21175"
     CDS             18899..19777
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009068281.1"
                     /locus_tag="C2142_RS21135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21175"
                     /product="sterol desaturase family protein"
                     /protein_id="WP_241002703.1"
                     /transl_table=11
                     /translation="MSGKLRAVLRRVAYPTLLVTVVSISVAALRWRWDLGRTSLLFLLG
                     TIGCLTALEQLIPYEPEWQPTIGEWGWYGVYFVLTMIGGALAQLPVTAAVGWLAPPHPT
                     LPLWAEIPAALLLGSLANYLVHRWSHSNPWLWRLHGVHHVPGKVNVANNGVNHVVDVLV
                     TQGTVQLSLALAGFSAESVFVVGLFVVAQGYFVHANVDVRLGVLNHVFAGPEQHRLHHS
                     ADLAEAGHFGSDLSVWDHAFGSFTWRPGRRPAVVGLQHPSEFPRTAEVITSHLQPWRRP
                     VRPVRVDDSPV"
     gene            20001..29501
                     /locus_tag="C2142_RS21140"
                     /old_locus_tag="C2142_21180"
     CDS             20001..29501
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (51-478). E-value:
                     2.7e-174. Score: 572.0. Matches aSDomain:
                     nrpspksdomains_C2142_RS21140_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (594-891). E-value: 2.8e-99.
                     Score: 324.2. Matches aSDomain:
                     nrpspksdomains_C2142_RS21140_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (957-1119). E-value: 1.6e-31.
                     Score: 101.8. Matches aSDomain:
                     nrpspksdomains_C2142_RS21140_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1489-1682). E-value: 2e-55.
                     Score: 179.5. Matches aSDomain:
                     nrpspksdomains_C2142_RS21140_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1768-1852). E-value: 1.9e-15.
                     Score: 48.9. Matches aSDomain:
                     nrpspksdomains_C2142_RS21140_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1876-2172). E-value:
                     1.1e-86. Score: 282.5. Matches aSDomain:
                     nrpspksdomains_C2142_RS21140_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2341-2753). E-value:
                     2.5e-96. Score: 314.7. Matches aSDomain:
                     nrpspksdomains_C2142_RS21140_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (2865-2926). E-value:
                     1.8e-13. Score: 42.6. Matches aSDomain:
                     nrpspksdomains_C2142_RS21140_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311644.1"
                     /locus_tag="C2142_RS21140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21180"
                     /product="non-ribosomal peptide synthetase/type I
                     polyketide synthase"
                     /protein_id="WP_148644105.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 5.3e-80, bitscore:
                     267.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 3.6e-172, bitscore:
                     572.0, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.7e-97, bitscore: 324.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 6e-47, bitscore:
                     158.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.2e-11, bitscore:
                     41.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.3e-62, bitscore:
                     210.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-103, bitscore:
                     345.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 3e-23, bitscore:
                     82.0, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDSCLAAASGPSDSPAPSDTARPARPGRPASTARSAPAAPAAPA
                     ADGPERIAIIGIGCRLPGGANDHRSFWQNLVDGKDCITPTPRSRYDVATLGSRDKARPG
                     RLVGGRGGYIDGFDEFDPAFFGISGREADHMDPQQRKLLEVAWEALEDGGQKPAELAGR
                     EVGVYVGAFTLDYKIVQFSDLSFETLAAHTATGTMMTMVSNRISHCFDFRGPSVSLDTA
                     CSSSLVAVHLAAQSLLRGETDLALAGGTLLHIAPQYTIAETKGGFLSPEGRSRTFDASA
                     DGYVRAEGVAVVALKRLSDALRDGDPVHAVVIGSGVNQDGRTNGITVPNPDAQVTLIER
                     VCAEAGIAPGSLQYVEAHGTSTPVGDPIEANALARALAIGRRPGDACYVGSVKTNIGHT
                     ESASGLAGLIKSALALKHRLIPPHINLETLNPAIDAAALPYRIPTEPTPWPAHQGPARA
                     GVNSFGFGGTNAHVLLEAAPEPEPEPAPEPEPVPAGRRPPGYTVLPLTARDAAALPELA
                     AGIRGELAGVRGGVPARLADLGHTLAHRRQHLDARLSVVHDSRESLDEALSAYLRGEPH
                     PRVLTGRRREARHRRLAWVFTGTGPQWWAMGRQLFEAEPVYREAVEACAGHLAELTGWS
                     LVEELAADETHSRMAETWLAQPANFAVQVGLAALWRSRGVHPDAVVGHSTGEVAAFYEA
                     GVYDLADAVRVVVHRSRLQQKLAGTGGMLAVALPEAEAVRRLRPYGGAVSVAAVNSPAS
                     LTLAGDTTVLAELAAALTAEQVFARPLAVEVPYHSARMDLIKDELLESLADLRARPARV
                     PLYLTGREGIAHGTELDAAYWWRNVRDGVRFQQAVERLDDDGFSLFLEIGPHPVLGRAI
                     QETVAARPADADRPEVCTLASIRRQEDEQAAFATSLAALHNLGVELDWSVLQPAGRPVP
                     LPRYPFRRDRHWVEPRSVEQVRQGRLDHPLLGRRLAGAEPAWEARPDAEALPYLEDHRI
                     QGQVLFPAAGYLEMAVQAVRALTGGADAALAGIELRKALFLPDDESRAVRFTLSAENGA
                     FTVTTTGPGEGQERTVHAAGTVRPGQRRRRPGHRLDAGAVRDRAVRHLAGPDCYTALAG
                     LGYHYGPAFQGIHEVWIGPGEALAAVRPTAAIAGQGAGHQVHPVLMDAFFQTLLTPQLL
                     VEAQAGTGIRLPLAIDEVRLDAVGERPLWVHATVTRDGGDELVGDIAVYDEDGVPLGGI
                     TGFRAADVEKASTAVGLATIDGWLAEPVWTALPDGPDTSEPLSGHPDHWLLLADAQGVA
                     EELAARIAARGGDCTLVRPGSDYRPAGDGRPATVDPGSGEDLRRLLSDRRAAGAADPAV
                     VVHLWNLDRPALAGADHATVAGHTGAGAYSLIALAALLPAELPDARLHIVTRTAQATTP
                     GEPVEPLGAPAWGIGRVLRHQELPGHPGKLVDLGPAGDPAEEAAALLCEFGLADEDEIA
                     LRAGRRLTSRLRPAEGLTGPLPPSLRPDGAYLVTGAFGALGRLLCRTLVRRGARRLILV
                     GRSPLPPREQWRGLDPASPAGRNTAFLRELEALGAQPVPVPLDVTDEAALGAWLAGYRA
                     LESPPIRGVFHLAGQVRDTLVPDLGREVFDAVHGPKVLGAFALHRQLADEPLDHFVLFA
                     SIASLLTTAGQTNYAAGNAFLDALAHHRRALGLPALSLDWGPWATGMIEELGLIDHYRN
                     SRGMSSLAPEAGMAVLERVLGQDRAQLLVATVVDWPVFLSWYPAPPPLVAELAAAARAS
                     APAPQHGSLLEALRAAGEEERRALLTERFTALAAAVLRVPAEQVGPATGLSGLGLDSLL
                     AMELRARLNTELGTAPPVVALLSNAPVAELVDRLHAGLAELIEEDGTGAAGAGVVRYED
                     ESSHPLTQNQKALWFLKQLNPDGFAYNIGGAVEVRVELEPELMAAAFRAMVERHPSLRA
                     NFVLDGGRAVQRVAAAAEPDFGVFDVEGLDWPEVHDLIVREYREPYDLERDPLVRFRLF
                     RRGPARWVIMKAVHHIISDAISTFTFIEELLAVYEGLRRGRAPELPPVGARYLDFLNRQ
                     NAFLAGREAPRMLDYWRSHLPAEVPVLSLPTDKPRPAVQTHNGASEFFVLDEELSARVH
                     ALAREHNVTVFMVLLSAYYLLLHAYSGQDDIVVGSPVTGRTDEEFAGVYGYFVNPLPLH
                     VSLAGAPTVAELLAQVRTTVLGGLDNQEYPFVLLVEKLGLQHDPSRSAVFQAMFILLHH
                     KVATEKYGYRLEYIELPEEEGQFDLTLSAYEDEAERRFHCVLKYNTDLFLPETTARLAR
                     HYVNLLDGLTAAAADHPATGLELLGREERALVLRRWSGAERRVAHEEPVHELILRAAAE
                     DPSAPAVAAPAESGPTARMDYGELAGRSRRAAARLRALGAGPGSVVGLCLEKSPELITA
                     LLAVLRTGAAYLPLDPGHPADRLAYMVEHAGAGLLIGDPERLAGLPARVVAPSELDRPS
                     AGSEAFEAFEDAPADLDAPAYVIYTSGSTGRPKAVRVSHRNLASAYQAWRGEYRLETDA
                     RVHLQMAGTSFDVFTGDVVRALCSGATLVLVGRELLFDTARLYEVMRTERVDAAEFVPA
                     VVRTVVGHCERSGLRLDFMRLLVVGSDVWKVEEYQRLQALCGPRTRLVNSYGLTEATID
                     SAYFEGPADGLEPGRMVPIGRPFPNSAFYLLDEQGRPVPPGVPGELWIGGSGVALGYVG
                     DEEQTARRFVTLPVGGEDGTEPVRLYRTGDLARWDTGGGVHLLGRADSQIKVRGHRIEL
                     GEIETRLAEWPGVERAVVTVRPDGSGDSVLCAYCVPAPGEALDRRELRHHLAGHLPTFM
                     IPAHFTELPALPLTPNGKVDVAALPAPRADAAGQAAEPPVTLYEVRMAEHWRALLGIGE
                     PGLQHDFFECGGSSIKLIELIHGLQGEFNISIPVSQLFRVTTLHGMAKTLEHIITGRIE
                     GAQPYLWFNREQQQTLFCFPPAGGHGLVYRQFAAHLPEYRLVAFNYVAGDDKVGRYADL
                     IGTIQPDGPCALLGYSLGGNLAFEVAKELERRGRAVPNVVIMDSHRIPESFTLGDEHVR
                     AFEHELAEHLQRHTGSDILAQETREQARDYLRFCSRTPNLGVITALVSVISDDAKVALH
                     AAGQHGAWHGSSATGTAVFRGFGTHAEMLDHGYIERNAGLARDILAGGAVHAS"
     aSDomain        20154..21434
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS21140_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="2.70E-174"
                     /label="C2142_RS21140_PKS_KS.1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="478"
                     /protein_start="51"
                     /score="572.0"
                     /tool="antismash"
                     /translation="IAIIGIGCRLPGGANDHRSFWQNLVDGKDCITPTPRSRYDVATLG
                     SRDKARPGRLVGGRGGYIDGFDEFDPAFFGISGREADHMDPQQRKLLEVAWEALEDGGQ
                     KPAELAGREVGVYVGAFTLDYKIVQFSDLSFETLAAHTATGTMMTMVSNRISHCFDFRG
                     PSVSLDTACSSSLVAVHLAAQSLLRGETDLALAGGTLLHIAPQYTIAETKGGFLSPEGR
                     SRTFDASADGYVRAEGVAVVALKRLSDALRDGDPVHAVVIGSGVNQDGRTNGITVPNPD
                     AQVTLIERVCAEAGIAPGSLQYVEAHGTSTPVGDPIEANALARALAIGRRPGDACYVGS
                     VKTNIGHTESASGLAGLIKSALALKHRLIPPHINLETLNPAIDAAALPYRIPTEPTPWP
                     AHQGPARAGVNSFGFGGTNAHVLLEAAP"
     aSModule        20154..25556
                     /complete
                     /domains="nrpspksdomains_C2142_RS21140_PKS_KS.1"
                     /domains="nrpspksdomains_C2142_RS21140_PKS_AT.1"
                     /domains="nrpspksdomains_C2142_RS21140_PKS_DH.1"
                     /domains="nrpspksdomains_C2142_RS21140_PKS_KR.1"
                     /domains="nrpspksdomains_C2142_RS21140_PKS_PP.1"
                     /locus_tags="C2142_RS21140"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       20640..20687
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0001"
                     /evalue="6.90E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="C2142_RS21140"
                     /protein_end="229"
                     /protein_start="213"
                     /score="18.1"
                     /tool="antismash"
                     /translation="GPSVSLDTACSSSLVA"
     CDS_motif       20829..20867
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0002"
                     /evalue="2.70E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="C2142_RS21140"
                     /protein_end="289"
                     /protein_start="276"
                     /score="14.0"
                     /tool="antismash"
                     /translation="FDASADGYVRAEG"
     CDS_motif       21060..21107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0003"
                     /evalue="1.20E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="C2142_RS21140"
                     /protein_end="369"
                     /protein_start="353"
                     /score="11.4"
                     /tool="antismash"
                     /translation="YVEAHGTSTPVGDPIE"
     CDS_motif       21168..21212
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0004"
                     /evalue="1.10E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="C2142_RS21140"
                     /protein_end="404"
                     /protein_start="389"
                     /score="11.5"
                     /tool="antismash"
                     /translation="GSVKTNIGHTESASG"
     CDS_motif       21780..21830
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0005"
                     /evalue="4.10E-03"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="610"
                     /protein_start="593"
                     /score="10.1"
                     /tool="antismash"
                     /translation="WVFTGTGPQWWAMGRQL"
     aSDomain        21783..22673
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS21140_PKS_AT.1"
                     /evalue="2.80E-99"
                     /label="C2142_RS21140_PKS_AT.1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="891"
                     /protein_start="594"
                     /score="324.2"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGTGPQWWAMGRQLFEAEPVYREAVEACAGHLAELTGWSLVEE
                     LAADETHSRMAETWLAQPANFAVQVGLAALWRSRGVHPDAVVGHSTGEVAAFYEAGVYD
                     LADAVRVVVHRSRLQQKLAGTGGMLAVALPEAEAVRRLRPYGGAVSVAAVNSPASLTLA
                     GDTTVLAELAAALTAEQVFARPLAVEVPYHSARMDLIKDELLESLADLRARPARVPLYL
                     TGREGIAHGTELDAAYWWRNVRDGVRFQQAVERLDDDGFSLFLEIGPHPVLGRAIQETV
                     AARPADADRPEVCTLA"
     CDS_motif       21963..22016
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0006"
                     /evalue="7.50E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="C2142_RS21140"
                     /protein_end="672"
                     /protein_start="654"
                     /score="15.8"
                     /tool="antismash"
                     /translation="AQPANFAVQVGLAALWRS"
     CDS_motif       22020..22130
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0007"
                     /evalue="7.60E-14"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="C2142_RS21140"
                     /protein_end="710"
                     /protein_start="673"
                     /score="43.8"
                     /tool="antismash"
                     /translation="GVHPDAVVGHSTGEVAAFYEAGVYDLADAVRVVVHRS"
     CDS_motif       22482..22529
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0008"
                     /evalue="2.20E-03"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="C2142_RS21140"
                     /protein_end="843"
                     /protein_start="827"
                     /score="10.7"
                     /tool="antismash"
                     /translation="LDAAYWWRNVRDGVRF"
     aSDomain        22872..23357
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS21140_PKS_DH.1"
                     /evalue="1.60E-31"
                     /label="C2142_RS21140_PKS_DH.1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="1119"
                     /protein_start="957"
                     /score="101.8"
                     /tool="antismash"
                     /translation="HPLLGRRLAGAEPAWEARPDAEALPYLEDHRIQGQVLFPAAGYLE
                     MAVQAVRALTGGADAALAGIELRKALFLPDDESRAVRFTLSAENGAFTVTTTGPGEGQE
                     RTVHAAGTVRPGQRRRRPGHRLDAGAVRDRAVRHLAGPDCYTALAGLGYHYGPAFQGI"
     CDS_motif       22947..23024
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0009"
                     /evalue="2.30E-13"
                     /label="PKSI-DH_m2"
                     /locus_tag="C2142_RS21140"
                     /protein_end="1008"
                     /protein_start="982"
                     /score="42.4"
                     /tool="antismash"
                     /translation="YLEDHRIQGQVLFPAAGYLEMAVQAV"
     CDS_motif       23325..23357
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0010"
                     /evalue="7.20E-03"
                     /label="PKSI-DH_m3"
                     /locus_tag="C2142_RS21140"
                     /protein_end="1119"
                     /protein_start="1108"
                     /score="9.4"
                     /tool="antismash"
                     /translation="GYHYGPAFQGI"
     aSDomain        24468..25046
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS21140_PKS_KR.1"
                     /evalue="2.00E-55"
                     /label="C2142_RS21140_PKS_KR.1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="1682"
                     /protein_start="1489"
                     /score="179.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GAYLVTGAFGALGRLLCRTLVRRGARRLILVGRSPLPPREQWRGL
                     DPASPAGRNTAFLRELEALGAQPVPVPLDVTDEAALGAWLAGYRALESPPIRGVFHLAG
                     QVRDTLVPDLGREVFDAVHGPKVLGAFALHRQLADEPLDHFVLFASIASLLTTAGQTNY
                     AAGNAFLDALAHHRRALGLPALSLDWGPWA"
     CDS_motif       24471..24569
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0011"
                     /evalue="5.60E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="1523"
                     /protein_start="1490"
                     /score="41.4"
                     /tool="antismash"
                     /translation="AYLVTGAFGALGRLLCRTLVRRGARRLILVGRS"
     CDS_motif       24891..25001
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0012"
                     /evalue="6.20E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="C2142_RS21140"
                     /protein_end="1667"
                     /protein_start="1630"
                     /score="67.0"
                     /tool="antismash"
                     /translation="LDHFVLFASIASLLTTAGQTNYAAGNAFLDALAHHRR"
     aSDomain        25305..25556
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS21140_PKS_PP.1"
                     /evalue="1.90E-15"
                     /label="C2142_RS21140_PKS_PP.1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="1852"
                     /protein_start="1768"
                     /score="48.9"
                     /tool="antismash"
                     /translation="LRAAGEEERRALLTERFTALAAAVLRVPAEQVGPATGLSGLGLDS
                     LLAMELRARLNTELGTAPPVVALLSNAPVAELVDRLHAG"
     aSDomain        25629..26516
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS21140_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.10E-86"
                     /label="C2142_RS21140_Condensation_LCL.1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="2172"
                     /protein_start="1876"
                     /score="282.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDA"
                     /tool="antismash"
                     /translation="SHPLTQNQKALWFLKQLNPDGFAYNIGGAVEVRVELEPELMAAAF
                     RAMVERHPSLRANFVLDGGRAVQRVAAAAEPDFGVFDVEGLDWPEVHDLIVREYREPYD
                     LERDPLVRFRLFRRGPARWVIMKAVHHIISDAISTFTFIEELLAVYEGLRRGRAPELPP
                     VGARYLDFLNRQNAFLAGREAPRMLDYWRSHLPAEVPVLSLPTDKPRPAVQTHNGASEF
                     FVLDEELSARVHALAREHNVTVFMVLLSAYYLLLHAYSGQDDIVVGSPVTGRTDEEFAG
                     VYGYFVNPLPLHVSL"
     aSModule        25629..28778
                     /complete
                     /domains="nrpspksdomains_C2142_RS21140_Condensation_LCL.1"
                     /domains="nrpspksdomains_C2142_RS21140_AMP-binding.1"
                     /domains="nrpspksdomains_C2142_RS21140_PP-binding.1"
                     /locus_tags="C2142_RS21140"
                     /monomer_pairings="Orn -> Orn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       25695..25808
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0013"
                     /evalue="1.20E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="C2142_RS21140"
                     /protein_end="1936"
                     /protein_start="1898"
                     /score="37.0"
                     /tool="antismash"
                     /translation="AYNIGGAVEVRVELEPELMAAAFRAMVERHPSLRANFV"
     CDS_motif       26013..26078
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0014"
                     /evalue="7.00E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="C2142_RS21140"
                     /protein_end="2026"
                     /protein_start="2004"
                     /score="18.7"
                     /tool="antismash"
                     /translation="VHHIISDAISTFTFIEELLAVY"
     CDS_motif       26418..26504
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0015"
                     /evalue="8.60E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="C2142_RS21140"
                     /protein_end="2168"
                     /protein_start="2139"
                     /score="37.5"
                     /tool="antismash"
                     /translation="DIVVGSPVTGRTDEEFAGVYGYFVNPLPL"
     CDS_motif       26556..26675
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0016"
                     /evalue="2.00E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="C2142_RS21140"
                     /protein_end="2225"
                     /protein_start="2185"
                     /score="49.1"
                     /tool="antismash"
                     /translation="RTTVLGGLDNQEYPFVLLVEKLGLQHDPSRSAVFQAMFIL"
     aSDomain        27024..28259
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS21140_AMP-binding.1"
                     /evalue="2.50E-96"
                     /label="C2142_RS21140_AMP-binding.1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="2753"
                     /protein_start="2341"
                     /score="314.7"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="RAAAEDPSAPAVAAPAESGPTARMDYGELAGRSRRAAARLRALGA
                     GPGSVVGLCLEKSPELITALLAVLRTGAAYLPLDPGHPADRLAYMVEHAGAGLLIGDPE
                     RLAGLPARVVAPSELDRPSAGSEAFEAFEDAPADLDAPAYVIYTSGSTGRPKAVRVSHR
                     NLASAYQAWRGEYRLETDARVHLQMAGTSFDVFTGDVVRALCSGATLVLVGRELLFDTA
                     RLYEVMRTERVDAAEFVPAVVRTVVGHCERSGLRLDFMRLLVVGSDVWKVEEYQRLQAL
                     CGPRTRLVNSYGLTEATIDSAYFEGPADGLEPGRMVPIGRPFPNSAFYLLDEQGRPVPP
                     GVPGELWIGGSGVALGYVGDEEQTARRFVTLPVGGEDGTEPVRLYRTGDLARWDTGGGV
                     HLLGRADSQIKVR"
     CDS_motif       27219..27260
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0017"
                     /evalue="2.80E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="C2142_RS21140"
                     /protein_end="2420"
                     /protein_start="2406"
                     /score="14.3"
                     /tool="antismash"
                     /translation="LAVLRTGAAYLPLD"
     CDS_motif       27450..27509
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0018"
                     /evalue="3.90E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="C2142_RS21140"
                     /protein_end="2503"
                     /protein_start="2483"
                     /score="28.6"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKAVRVSH"
     CDS_motif       28038..28127
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0019"
                     /evalue="1.70E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="C2142_RS21140"
                     /protein_end="2709"
                     /protein_start="2679"
                     /score="45.9"
                     /tool="antismash"
                     /translation="PPGVPGELWIGGSGVALGYVGDEEQTARRF"
     CDS_motif       28227..28289
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0020"
                     /evalue="6.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="C2142_RS21140"
                     /protein_end="2763"
                     /protein_start="2742"
                     /score="34.3"
                     /tool="antismash"
                     /translation="LGRADSQIKVRGHRIELGEIE"
     aSDomain        28596..28778
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS21140_PP-binding.1"
                     /evalue="1.80E-13"
                     /label="C2142_RS21140_PP-binding.1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="2926"
                     /protein_start="2865"
                     /score="42.6"
                     /tool="antismash"
                     /translation="AEHWRALLGIGEPGLQHDFFECGGSSIKLIELIHGLQGEFNISIP
                     VSQLFRVTTLHGMAKT"
     CDS_motif       28851..28880
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0021"
                     /evalue="1.40E-02"
                     /label="NRPS-beforete1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="2960"
                     /protein_start="2950"
                     /score="8.6"
                     /tool="antismash"
                     /translation="TLFCFPPAGG"
     CDS_motif       28998..29072
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21140_0022"
                     /evalue="6.60E-12"
                     /label="NRPS-te1"
                     /locus_tag="C2142_RS21140"
                     /protein_end="3024"
                     /protein_start="2999"
                     /score="37.7"
                     /tool="antismash"
                     /translation="QPDGPCALLGYSLGGNLAFEVAKEL"
     gene            29491..30795
                     /locus_tag="C2142_RS21145"
                     /old_locus_tag="C2142_21185"
     CDS             29491..30795
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311650.1"
                     /locus_tag="C2142_RS21145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21185"
                     /product="cytochrome P450"
                     /protein_id="WP_346766389.1"
                     /sec_met_domain="p450 (E-value: 4.9e-23, bitscore: 80.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPETTDPRAAQAPAGRPEAAGTRLPPPGSPPREADLPMLRQHRP
                     LAYPFEPLGLELHPRYAELRDQPLARIRLPYGDGAWLVTRYEDVRTVLADPRFSLAEAM
                     GQDQPRMRPVARTGAGLFSTEPPEHTRLRSLVAREFSARRVERLRARAGELAGELVDAM
                     VAAGPPADLVEDFAIPMPTTIICEVLGIPAEDHRMLWHWAETVLSAVTPGEVLAEEGRA
                     FIAYMAGVLDLRGREPGEDLLTVLVRACREQGLITEEELLSIACDLLIAGFVSTTNQIG
                     NFFHQLLVNPEELHRLREKPELIPKAVEELMRYVPLLTGFSLPRYATADVELGGVVVRA
                     GDAVMIATAAANRDPDVFEEPERLVLDRPGNPHVGFGHGVHYCIGAHLARLELQVAIGT
                     VLDRLPGLRPAVPEDELNWKADAMVNGLQALPVAW"
     gene            30876..32582
                     /locus_tag="C2142_RS21150"
                     /old_locus_tag="C2142_21190"
     CDS             30876..32582
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010262586.1"
                     /locus_tag="C2142_RS21150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21190"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_148644919.1"
                     /transl_table=11
                     /translation="MIIVGGGLGGLSTGCYARMNGYRTQIFEMHEIPGGSCTGWDRSDF
                     TFDWCISWLLGNGPGNEMYQIWLELGALQGKEMRHFDAFNIVRGRDGRAVYFYSDPDRL
                     EAHLLGISPADAAPIREFCNGIRTFRKALAVYPFLKPVGLMGRVERWRMLASFLPYFST
                     IRKSITVLMTDYAQRFREPLLREAFNFILYEKHPAFPVLPFYFQLASHANRAAGVPEGG
                     SLALARSIEERYRRLGGEITYNAKAEEILVENDRAVGVRLSDGREYRADIVVSAADGHT
                     TVMKLLKGRYLNDTYRRLYTSLIDEPGQLSPGYVSLFLGLRRPFPEGDPCTTYLLGERE
                     TDGLTGIRCPSMNVQFRTRHYPELAPRESTVVFATYFSDIGPWRELREGPEQSSRVRRG
                     EELHTLPVKHGREYTAAKRKVRGTIVSFLDERFPGFKDAVAVADVSTPLTQVRYTGVYD
                     GTFPGWNPFVEGSETVEQEIKKNGPVLPGLENFYLSGVWATIGGLIRAAAAGRHVMQFI
                     CRDDGVEFHAEIDPSAPPPTHLILPVGRPPQQAGPVGEIPSTSTAPTGALA"
     gene            32579..33637
                     /locus_tag="C2142_RS21155"
                     /old_locus_tag="C2142_21195"
     CDS             32579..33637
                     /NRPS_PKS="Domain: PKS_ER (34-349). E-value: 5.9e-16.
                     Score: 50.4. Matches aSDomain:
                     nrpspksdomains_C2142_RS21155_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955587.1"
                     /locus_tag="C2142_RS21155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21195"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_148644106.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 3e-14, bitscore:
                     52.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIEKWVVREHLDGVPDVNRVYRKVVEDVTVGLRPDEMLFRTRYV
                     SVDPYQNGLALETPIGHHMGGDSVMEVLEAGPEAAFRVGDLVQGFGGWRSHVVHNGAEE
                     VWKTGTFPMVFPAYRRLDPAWYDEKLPLSTALGIMGAPGMTAWGTLTRFMTVRPGDTVV
                     ISGASGSVGTLVGQLARRAGAGRVVGTTASPGKAEYLKELGFDEVVLYDQADDAGKARE
                     ALLHAAPDGVDRYFDNLGGTVTDAVFTMLNVNSQVAVCWQWATTVNGELTGPRLLPYIM
                     FPRTTIRGIFAQEWFNEPELAEMHQDLGALVRSGEIRYHQTVHKGFDAIPQAYRSLYVD
                     REANRGKVLVEV"
     aSDomain        32681..33625
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS21155_PKS_ER.1"
                     /evalue="5.90E-16"
                     /label="C2142_RS21155_PKS_ER.1"
                     /locus_tag="C2142_RS21155"
                     /protein_end="349"
                     /protein_start="34"
                     /score="50.4"
                     /tool="antismash"
                     /translation="PDEMLFRTRYVSVDPYQNGLALETPIGHHMGGDSVMEVLEAGPEA
                     AFRVGDLVQGFGGWRSHVVHNGAEEVWKTGTFPMVFPAYRRLDPAWYDEKLPLSTALGI
                     MGAPGMTAWGTLTRFMTVRPGDTVVISGASGSVGTLVGQLARRAGAGRVVGTTASPGKA
                     EYLKELGFDEVVLYDQADDAGKAREALLHAAPDGVDRYFDNLGGTVTDAVFTMLNVNSQ
                     VAVCWQWATTVNGELTGPRLLPYIMFPRTTIRGIFAQEWFNEPELAEMHQDLGALVRSG
                     EIRYHQTVHKGFDAIPQAYRSLYVDREANRGKVL"
     gene            complement(33713..34288)
                     /locus_tag="C2142_RS21160"
                     /old_locus_tag="C2142_21200"
     CDS             complement(33713..34288)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962128.1"
                     /locus_tag="C2142_RS21160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21200"
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="WP_148644107.1"
                     /transl_table=11
                     /translation="MKQLRGTELKRLHRQWRRSNEFRLALILENLQSPFNVGSVVRTAA
                     AMGAEKLYLTGDTPSVRSSGAQKAAMGTDKYLKVEHFPTVAEAVASAKADGYKVVGLEL
                     ADEAVPMFAAELTPAVAFVLGHEDRGITPDALALCDQVVFVPQLGRVGSLNVSAAATVA
                     CYEARRQGYAISGTPDGSDAGGLDLDDE"
     gene            complement(34285..34929)
                     /locus_tag="C2142_RS21165"
                     /old_locus_tag="C2142_21205"
     CDS             complement(34285..34929)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003956140.1"
                     /locus_tag="C2142_RS21165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21205"
                     /product="methyltransferase"
                     /protein_id="WP_206670993.1"
                     /transl_table=11
                     /translation="MMSGSHYFTGAPEVASERRPITVTLPDLTLELTTDAGVFSRSRLD
                     PGTRVLLEHAPPPRVRGPILDVGCGYGPITLTWASRRKRLPVWGVDVNTRALELVRLNA
                     ESLGLGNVQAALPEDVPEDLRFAAIYSNPPIRVGKAALRRLLHQWLGRLTPDGSAFLVV
                     QKNLGSDSLQKWLNDQGYPTSRVTSVNGFRILEARPRPEGAGPESGRGTTS"
     misc_feature    34920..34934
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.95"
                     /tool="antismash"
     gene            35176..35370
                     /locus_tag="C2142_RS21170"
                     /old_locus_tag="C2142_21210"
     CDS             35176..35370
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522839.1"
                     /locus_tag="C2142_RS21170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21210"
                     /product="hypothetical protein"
                     /protein_id="WP_148644108.1"
                     /transl_table=11
                     /translation="MPQNHEDYLDEVSETVEPDDAAEEGDEYDELAERRALGADPATEV
                     ADVAEQSRIVQLDEDEYRE"
     gene            complement(35465..38176)
                     /locus_tag="C2142_RS21175"
                     /old_locus_tag="C2142_21215"
     CDS             complement(35465..38176)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015651.4"
                     /locus_tag="C2142_RS21175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21215"
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="WP_162002517.1"
                     /transl_table=11
                     /translation="MAVVTGRTDSDTGGARAGGISGQTDPGISPDIPDIPAPAEASGTE
                     DTAAPEHAEGTADARDPRGTEGTEGTADARGAAGTGRIRQPVALIRCLAGLAAIALCLL
                     LADYARATIGGIAADVAAAARLVPRPLAGIAGGLSTAALLLVPAYSAARRLLGSAPDRR
                     RTLQHLSDGLLAAVVAYGLSLALDLWVDGAAPASLLHALTQRLPGGGPAHTEPVYGYLA
                     PVLAFLTASGARERRMPRIVLTVSGLAGLAAGYATPTALLLGLLIGWTAAHGTRYAVGT
                     PDPRPRPALLLHSLREAGLRPVAAAPDGPDRYLVRQEADRPDLDVQLLDRQAVTAALVQ
                     RAWRRLRLRTAPHPRALRSLRTGLEHEALVSYAAVAAGVRTRRIAATVELGRDTALVAY
                     ERLPGRTLDQLADDELTDALLTDAWTQLSLLQRREISHRALVPSALLVDEAGAVHLVDL
                     ADGDIAASELVLQCDIAQLLTTLALRTGAERAVRSAVTVLGPDAVGAALPLLQPIALAR
                     TTRTALRRAAAAQRAAATPAAPPAGTPAGALAKASSKAKAARAAAPPPPPVELLDAIRA
                     EVLRTRPQAPVRAVKLERLRPRTLMAVCGGVAAGWLLLPQLFASEQNPVATIADADPLW
                     LVLALLAATASHFTAAMGFVGFVPERLDFRHAVLAQVAGAFVKLVSPGGVGGVALNTRF
                     LQRAGLPTAQALSSVGVGQLFSLVLHLLQLGAFVYLLGLEPGGSELDALPAVVGGLAGA
                     AVLLAGVSAVPPARRWLTARLRPLTSEVLPRLLELLRSPQRLAVGIAGQLLVSLCLVAC
                     LYCCARAVGREPAFASVAVVFLIGNAVGNAAPTPGGAGAVDSALVTLMEHTASMEEGGA
                     LASVALFRLLTLVLPVLPGWAAFTWLQRRGAL"
     gene            complement(38243..39004)
                     /locus_tag="C2142_RS21180"
                     /old_locus_tag="C2142_21220"
     CDS             complement(38243..39004)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (9-181). E-value: 3e-16. Score:
                     51.8. Matches aSDomain:
                     nrpspksdomains_C2142_RS21180_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016577197.1"
                     /locus_tag="C2142_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21220"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_148644110.1"
                     /sec_met_domain="adh_short (E-value: 1.4e-34, bitscore:
                     118.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYPALATRTAVVTGAASGMGEATARLLAAGGARVALLARRTGRL
                     DALAAEITAAGGRALAVTADITDQASVDAAAKAVHDAYGPVDLVVNNAGVMLPNPLADG
                     RVDEWTRMIDTNLTGALRIVRAFSPDLTAAAAEGRTADLVNVSSIASHVVFPDYAVYGA
                     TKAALTQLSAALRTELGPRDVRVSAIEPGLTDTELGGHIDNPVLREQLGGMFAAIPALT
                     ADDIADLIGYTVTRPRHVNLRHLVALPTRQA"
     aSDomain        complement(38462..38977)
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS21180_PKS_KR.1"
                     /evalue="3.00E-16"
                     /label="C2142_RS21180_PKS_KR.1"
                     /locus_tag="C2142_RS21180"
                     /protein_end="181"
                     /protein_start="9"
                     /score="51.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TAVVTGAASGMGEATARLLAAGGARVALLARRTGRLDALAAEITA
                     AGGRALAVTADITDQASVDAAAKAVHDAYGPVDLVVNNAGVMLPNPLADGRVDEWTRMI
                     DTNLTGALRIVRAFSPDLTAAAAEGRTADLVNVSSIASHVVFPDYAVYGATKAALTQLS
                     AALRTELGP"
     CDS_motif       complement(38882..38971)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C2142_RS21180_0001"
                     /evalue="3.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="C2142_RS21180"
                     /protein_end="41"
                     /protein_start="11"
                     /score="16.3"
                     /tool="antismash"
                     /translation="VVTGAASGMGEATARLLAAGGARVALLARR"
     gene            39181..40068
                     /locus_tag="C2142_RS21185"
                     /old_locus_tag="C2142_21225"
     CDS             39181..40068
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014177559.1"
                     /locus_tag="C2142_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21225"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_148644111.1"
                     /transl_table=11
                     /translation="MENTVGDFLRSRRARIRPEEVGLPSHGRRRVQGLRREEVAQLAGV
                     SVDYYIRLEQGRGGSASDAVLDAVARVLGLDDVEAAHLRSLTRPSRTAAVPRGRQQVRE
                     GTRLLLDLMPGVPAFVLGRRMDVLAWNALGDAVHGFSARPSGEANAARHAFLDPAAREF
                     YPQWEAVAAETVAYLRLDAGRHPDDARLAALVGELSVRSEEFRRLWADHQVRQKTHGVK
                     LIRHPLVGELDFGYETLAVNGSADQLLVVFTARPGSPTAQKLALLASWTAEGAPAESAP
                     AEGAPEREAPAAAD"
     gene            40141..40407
                     /locus_tag="C2142_RS21190"
                     /old_locus_tag="C2142_21230"
     CDS             40141..40407
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544440.1"
                     /locus_tag="C2142_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21230"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_148644112.1"
                     /transl_table=11
                     /translation="MSACEDLTAAPLDIEPLPPTDGCADCVAQGRRDWVHLRVCLDCGH
                     IGCCDFSPQRHATAHFHNSSHPVIRSYEPGEDWRWCYVHEVMG"
     gene            40557..40826
                     /locus_tag="C2142_RS21195"
                     /old_locus_tag="C2142_21235"
     CDS             40557..40826
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_21235"
                     /product="hypothetical protein"
                     /protein_id="WP_148644113.1"
                     /transl_table=11
                     /translation="MTKLMPSSTAKLRRGTQELLERRGMAMNPGPMPPRLRTNAPPAGG
                     AAAGGVTFRHGGRDADVAAMHSAPAMHAELKGHRHRGAEKHSAH"
     gene            41080..42321
                     /locus_tag="C2142_RS21200"
                     /old_locus_tag="C2142_21240"
     CDS             41080..42321
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014146339.1"
                     /locus_tag="C2142_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21240"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_148644114.1"
                     /transl_table=11
                     /translation="MNTTQRHRRWTTLAVSGALLAGVAAGAATPALAADRTAGSASSAD
                     AAARPAGPLDREAMAKTLAGLPDDGITGALVRVDGRGGRWAGTAGDVPADARFRIGSIS
                     KVFTATVVLQLAAERKLDLDGSVQQYLPGLLPASYPPVTVGQLLDHTSGLPGGGGLTSG
                     DGTESWFAAHKADSWTPAQVVADAVKQPMGFAPGTAQQYNGINTFVAGMVVEKVTGHTF
                     AREVQTRIARPLGLRDTVVPDRDDLTLTGPHAKVSVDVGGQAGPRQLVDVTEQSPWPWA
                     EGGMISSAADLDRFMTALFRGRLLPPAQQAELFDVPDVPNHRNKNCEIGPTAGHACFSK
                     GLMSATLPNGVVVWGKTGSRPGYTSGVFATKDLSRKVVYSINPTGISGAEFPRMWQIVT
                     TSFGSGQKYGDQPE"
     gene            42395..43372
                     /locus_tag="C2142_RS21205"
                     /old_locus_tag="C2142_21245"
     CDS             42395..43372
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548646.1"
                     /locus_tag="C2142_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21245"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_206670994.1"
                     /transl_table=11
                     /translation="MADLMTEEPVELQLERYRTELTGYCYRMLGSVFEAEDAVQETMIR
                     AWRGHRGFEGRAALRSWLYRIATNVCLDALNGRNGRARPMDLAGPSTVATATDARLPEV
                     TWIGPAPDGRVVSETGDPAEVAAQRESVRLAFVAALQRLAPRQRAVLILREVLGWKAAE
                     VAELLGVTVASVNSALQRARSVLSTDAAAVRPASALDEDHQALLSRYVSAFEAYDMDGL
                     AALLHEDVTLNMPPFELWLTGHADIREWMLGPGHGCRGSRLVPVEANGSPAFGQYRPSP
                     AGGHEPWALIVLEVSEGRITGLTNFLDTDVLFPLFGLPPRLDAE"
     gene            complement(43280..43648)
                     /locus_tag="C2142_RS21210"
                     /old_locus_tag="C2142_21250"
     CDS             complement(43280..43648)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.4"
                     /locus_tag="C2142_RS21210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21250"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_148644115.1"
                     /transl_table=11
                     /translation="MSHTRRSGPTSVNTNLETPLTLSQDQRLTCDLAALPGADLAVVDA
                     LARLRLAAARHGVRVELKNVSGPLRELLAFSGLAGVLPPVAQDGLPDLLGVQPRRKAEE
                     REEHVGVEEVGEPGDPAL"
     gene            43849..44415
                     /locus_tag="C2142_RS21215"
                     /old_locus_tag="C2142_21255"
     CDS             43849..44415
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.4"
                     /locus_tag="C2142_RS21215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21255"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_148644116.1"
                     /transl_table=11
                     /translation="MSAEPSKPEPSKPESLKSEPLKSEPSGPEPLKSREEWLASLPRVY
                     AAAGCVLRDASGRILIVKAGYREHWQFPGGTIDLGEGPAECAARELTEETGLVRPAGDL
                     LAVSWTHPSAELDHPAGHFLFDFGTVPDGTPVTVPAGELDDYRWAGDEEALELLGPARS
                     LRLRAAMEAAADGRVRIVTTHVSGF"
     gene            complement(44459..45208)
                     /locus_tag="C2142_RS21220"
                     /old_locus_tag="C2142_21260"
     CDS             complement(44459..45208)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035726.1"
                     /locus_tag="C2142_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21260"
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_148644117.1"
                     /transl_table=11
                     /translation="MENPVVPKTTPLRLDDLIDAIKKVHSDALDQLSDAVIAADHLGEL
                     ADHLIGHFVDQARRSGASWTDIGRSMGVSKQAAQKRFVPKDPGTPADLDPSQGFSRFTP
                     RARHVVMESQEEARRAGNAEIGTGHILLGLLAEPEGLAVKALAAQGITPEAVREAVTAT
                     LPAAADETPGLIPYDAEGKKVLELTFREALKLGHNYVGTEHILLALLEQANGAGPLTDL
                     GVDKAEAETFTAEAVAAYIAARADTQE"
     gene            complement(45309..45755)
                     /locus_tag="C2142_RS21225"
                     /old_locus_tag="C2142_21265"
     CDS             complement(45309..45755)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104637.1"
                     /locus_tag="C2142_RS21225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21265"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_148644118.1"
                     /transl_table=11
                     /translation="MIFRTATRQDLPAVIALLADEDRVTDPATVRVDEAYARAFADVDA
                     DSRNELMVLDEGDGTVLGCLQLTYIPGLGRHGEERALIEAVRVRADRRGAGLGRELLTR
                     AVGRARDRGCTLVQLTSNKRRTEAHRFYASLGFARSHDGFKLTI"
     gene            45828..46400
                     /locus_tag="C2142_RS21230"
                     /old_locus_tag="C2142_21270"
     CDS             45828..46400
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540659.1"
                     /locus_tag="C2142_RS21230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21270"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_148644119.1"
                     /transl_table=11
                     /translation="MRILTAPEAEVPGELKLQVAALQDQAWPGPPVPSTALVHDPALRP
                     VSMLLLDGDRVVAALDVLSKELDHAGRTFAASGLSAVVTDRARRGRGYGRRLVAAARAA
                     VVQGGADLGLFTCDRGLRGFYEGAGWELLPGAVLVGGTAEEPFPSDQDGFDKVTMAGFF
                     TDRAARHRPDFEGRRIALHPGDIDRLW"
     gene            complement(46560..47297)
                     /locus_tag="C2142_RS21235"
                     /old_locus_tag="C2142_21275"
     CDS             complement(46560..47297)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837107.1"
                     /locus_tag="C2142_RS21235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21275"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_148644120.1"
                     /transl_table=11
                     /translation="MSRTHALTTTDDRTLVWDGCLNVRDLGGIRTTDGGRTAHRAIVRA
                     DNLDRLTAEGWDTLLDHGIRTVVDLRNIEEYKPLLPLPEGVELIRVPLDELAGPAWWET
                     YGRLDGTPLALRPYLDHCAHAAAELVTTIAGARPGGLVVHCGAGRDRTGLAALLLLALA
                     GAEPSEIVADYLLSAPNVRPLYGMLGLPDQHLRIDAVLSEAGTTAEAALYATLDGFDPA
                     GYLLAAGVDPADLAAVRARLLDA"
     gene            complement(47413..48183)
                     /locus_tag="C2142_RS21240"
                     /old_locus_tag="C2142_21280"
     CDS             complement(47413..48183)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954336.1"
                     /locus_tag="C2142_RS21240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_21280"
                     /product="VC0807 family protein"
                     /protein_id="WP_148644121.1"
                     /transl_table=11
                     /translation="MSQTLSAPATVTATVAVAVAVAKSTDGTATDDTATAKARNPLAAG
                     LRPLALDVAAPLAGYYLLHSAFGMSEFAALAWSGAIPAVRTVAGLLRERRLNLWASMML
                     GVNVVGLALTTVTGDARLMLAKDGALSGSLALAILVSALIGRPLMSPMVMPFLTRGDRA
                     RSAAWQRLAEGRAARSASFRRYERLLSGIWGVALLAECTARVVGAFTLPVSTMAWLSTV
                     LLVGAIVVGSVLGQTAAEPMEKLVRAEAAEPTVC"
     misc_feature    49067..49082
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.93"
                     /tool="antismash"
ORIGIN
        1 gccatcgcgc agctgctcgg cgaggaccgg gtggtgctgc gggaccgggt gccggagtcg
       61 ctgcggctgc tcaccgagca ggggttcatc cagcccgccg gctgagcacc cggccccgcg
      121 ccggccggcc ccgccgggcc gaaggtccgg agcaccgaag cactaaaggg ccgaggagcc
      181 ggggccggac gagcggggtc gaagagccag ggtccaaggg caagggccga agcgccggag
      241 cccgacgccg gaaccaccgg ctccggccgc ccggccagcc cgaccggctc cggccgtccc
      301 gacccggccc gttcgggacg cgggcccggt tcatctctct gtagtccctg gttcgcccgt
      361 cggtcgccga acagctgccc ctcgttggcc cccgactgtg aggctctgtc cacaggccgt
      421 ggacagagct gggggcccag gagtggagac gacgaccgcg acggtgggcg gcgcggtgct
      481 cgcgctgttc ggcggcgtgc tgctgctctg gtgcgccgcc gaagtacgcc ttcgccacgg
      541 tgtgcgccgc cggggcatac cggcggtggc caccgtggtc gcggagtcgg acacccacag
      601 cgaactcgac agctcgccgc tgctgacctt ctccgcgccg gccgcgatcg acggtcccgg
      661 tgcggcgcgc cgggccgagg tggtgctcgc ccggccgcgc ggccataccc cgctgcgccg
      721 cccgccgcgc ttctcgcccg gcacgtccgt ccgcatctcc tacgacccgc gtcggccgag
      781 ccgggtggtg ctggcggcgg cggagaccgg cggtgtcgtc gtgacggacc tgctgtggac
      841 ggcgctgggc gtcggctgcc tggccgcggg cgccgccctg ctggccgccg ccgccaccaa
      901 ctgaggcgtc ggccgacccc ggggcccggc gtcccgaacc ggccatgacg tcggattccg
      961 gccacccggt ccggcggtgg tccggtcgcg gtcctgcggc cgttcggccg gggtcgagcc
     1021 ccggtccggt ggcggtctgc cgaggtccgg cccggtcggg tccggtccga cccgggcgct
     1081 cccccgggct gctcccgaag cgctcccggc accccctacc accagcccgg tcgccgggcg
     1141 ccgattttcc gttgacagat tttgaaatcc gtcattccat ccttcggaac ccgccgaagc
     1201 ccccctccac ggggcgcgat cctccatcat cgggttaccg ttcgagtggc gtcggtcggc
     1261 cttgccggtg aaaaagcagg atccgtccgt ttgacaaggg tggccggggt acggtcacac
     1321 tccgctggtg gggtcgtcgt acagcggctg ccccgggacg gtggaggggt cgggcggagc
     1381 gcagcccgtg ctgccggcgc cgaccagccc acataacgac cgggagagaa gagcgaaggt
     1441 gtccccgagc agcgagaccg cgcacggaca gcgactcgtc attgtcgagt cgccggccaa
     1501 ggcgaagacg atcaagggct acctgggccc cggctacatc gtcgaggcga gcgtcgggca
     1561 catccgcgac ctgcccagca cggcggccga ggtgccggac aagtacaccg gcgaggtgcg
     1621 ccgcctcggc gtggacgtcg accacgactt cgcccccatc tacgtggtca acgcggacaa
     1681 gaagtcccag gtcagcaagt tgaagtcgct gctcgcggag tccgacgagc tcttcctcgc
     1741 caccgatgag gaccgcgagg gcgaggccat cgcgtggcac ctccagcagg tgctcaagcc
     1801 caaggtgccg gtgcaccgga tggtgttcca cgagatcacc aagtcggcga tccaggaggc
     1861 cgtggccaac ccgcgcgagc tgaaccagcg cctggtcgac gcccaggaga cccgccgcat
     1921 cctcgaccgc ctctacggct tcgaggtctc gccggtgctg tggaagaagg tcatgccgaa
     1981 gctctcggcg ggccgcgtgc agtccgtcgc gacccggctg gtggtcgagc gcgagcgcga
     2041 gcggatggcg ttccgcagcg cctcgtactg ggacctggtc ggtaccttcg gcaccggccg
     2101 cagcccggcc gacgccgcca acccggagac cttcggcgca cggctgtccg ccgtcgacgg
     2161 caagcggatc gccagcggcc gcgacttcgg ctcggacggc cggctcaagg ccggcagcac
     2221 caataccctg cacctggacg agcaggccgc ccgcgcgctg gccgccgccc tggagcagac
     2281 cgcgttcagc gtccgcagcg tcgagtccaa gccctaccgc cgctcgccgt acgcgccgtt
     2341 ccgcaccacc acgctccagc aggaggccag ccgcaagctg ggcttcggcg ccaagcggac
     2401 catgcaggtg gcccagaagc tgtacgagaa cggcttcatc acctacatgc gcaccgactc
     2461 gacgacgctc tcggacaccg cgatcgcggc cgcccgcgcg caggtcaccc agctctacgg
     2521 cgccgactac ctgccggacg cgccgcgcac ctacgccagc aaggtcaaga acgcccagga
     2581 ggcgcacgag gccgtccgcc cgtccggcga ccgcttccgc acccccgccg agaccggtct
     2641 gagcggcgac gacttccggc tgtacgagct gatctggatg cgcaccgtcg cctcccagat
     2701 gaaggacgcg gtcggccagt cggtcaccgt caaggtcggc gggcgtgccg cggacggccg
     2761 ggacgccgag ttctccgcct ccggcaagat catcaccttc cacggcttcc tgaaggccta
     2821 cgtcgagggt gccgacgacc cgaacgccga gctggacgac cgcgagcgcc ggctgccgca
     2881 ggtggccgag ggcgacccgc tggccgccga tcagctcacc cccgagggcc acgccaccaa
     2941 gccgccggcc cgctacaccg aggcctcgct ggtcaaggag ctggaggacc gggagatcgg
     3001 gcgcccctcc acctacgcct cgatcatcga caccatcatc ggccgccgct acgtcttcaa
     3061 gaaggggacg gcgctggtgc cgtcgttcct ctccttcgcc gtggtcaacc tgctggagaa
     3121 gcacttcggc cggctggtcg actacgactt cacggcgaag atggaggacg acctcgaccg
     3181 gatcgcggcc ggcgaggcca agtccgtgcc gtggctgaag cgcttctact tcggtgaggg
     3241 cgagggccac gcgaccggcg gggcagccga ggccggcaac ggcgacggcg accacctggg
     3301 cggtctcaag gagctggtca ccgacctcgg cgcgatcgac gcccgggaga tcagctcgtt
     3361 ccggatcagc gacgacatca ccctgcgggt cggccgctac ggcccgtacg tcgagcgtgc
     3421 gtccgccgtc gagggcgagc ccggccagcg cgccgacatc cccgacgacc tgccgccgga
     3481 cgagctcacc gtcgagctgg ccgaggagtt gctggccagg ccgagcggcg acttcgagct
     3541 aggccaggac ccggtcagcg gcaaccagct ggtcgccaag gacggccggt acggcccgta
     3601 cgtcaccgag atcctgcccg agggcacgcc gaagaccggc aagaacgccg tcaagccgcg
     3661 gaccgcctcg ctgctcaaga cgatgtcgct ggacaccgtc acgctcgagg acgcgctgaa
     3721 gctgctgtcg ctgccgcgcg tggtcgggac ggacccggag ggcgtggaga tcaccgcgca
     3781 gaacggccgc tacggcccgt acctcaagaa gggcaccgac tcgcgctcgc tcaccagcga
     3841 ggagcagatg ttcacggtca ccctggagga ggccctggcc atctacgccc agccgaagca
     3901 gcgtggccgg gccgccgccg cgccgccgct caaggagctg ggcaccgacc cggtcagcga
     3961 gcgtccggtg gtggtgaagg acggtcgctt cgggccgtac gtcaccgacg gcgagaccaa
     4021 cgcgaccctg cgcaaggacg acgaggtcga gaccatcact ccggaacgcg gctacgagct
     4081 gctggcggag aagcgggcgc gcgggccggt gaagaaggcg gcgaagaagg ccccggcgaa
     4141 gaaggccgcc gccaagaaga cggcgaccaa gaccgcggcg aagaagaccg ccacggccaa
     4201 gaccgcgacc gccaagaaga cgaccacggc cacgaccgcg accgccaaga agacggcggc
     4261 caagaagacg gccgcgagca agaccaccgc caccgacgag ggctgacccc cgtccggcgg
     4321 caccgggccc gcacctcccc ttccggaggt gcgggcccgt ggtgtcggga ggcgcggccc
     4381 gccgtcgtcg caggtgcggg cccggcgtcc tcgggggagt ggacccgccg tcgtcgcagg
     4441 tgcgggcccg gcgccctcga aggagtgagc gcggcgtcct cggaggagtg gtcagggagc
     4501 tgtgcggggt gcgtcacaac cctgcaatga cggcgaaccg gagggccgct cacccgtttg
     4561 tggcaaccgt cgaccgctac gctgaccgta tgacgagcga ggagcagccc acccccagcg
     4621 ccgccgcggc cgccagagcc ggcacgcccg acctgcccga ggtcgcgccc gcgggaaccc
     4681 ccggcgagcg ggcccgcgca ctgctgcggc tgcgcccgta ccgccggctc tggaccaccc
     4741 agctgatcgg cggcaccgcc gaccggctcg gcctgctggt gctgctcgcg ctcaccgtga
     4801 tcgcggccgc gctcggcggg cagttcggcg acctgccgcg cagcctcgcc ttcgcggtcg
     4861 ccgccgtctt cgccgtccgg ctggccgcca cggtgctggt cggcgcggcc ctgctcggcc
     4921 cggtgcacgg gctgctcagc gggaagctcg accgccgctg gacgctgttc ggcgccgacg
     4981 tgctgcgggt cgtgctgatc ggcgtcgcgc cgtggtggat cgtctggctg ggctccggct
     5041 ccggtgcgga cgccaggccc tccggggccg ccacctacct gctgctcggc accgtcttcg
     5101 tgaccggcgc cgccgagcgg gtctgggcga tcgccaaggc cgccgccgtc cccgccctgc
     5161 tgccgccggc caacccctac gccccgcccg ccgagcggcg cccgtccgcc gccaacctgg
     5221 acaccgtcgg gacgctggac cggcgcaccg gctgggccac cgtgccgctc gcggcggtcg
     5281 cgctggtcgc gctcacgctg gtcggcaacg tcttcgcggc ggtggcctcg gactggctgc
     5341 gcgcccacca gaccaccttc gccgccctcg gggcggccgc cctgttcgcc gtctcggccg
     5401 tccgggtcta ccagcacgag ctgcccggcg gcccggcctc cgtggtcccg cactccccgc
     5461 tgcggggcct gcgcgccccg accgacgcga cccccgggcc cgcgctgggc aagggccgca
     5521 ccggctccgc cccgtacttc accttcgcgg tcgccgccgc ctacgcatcg atggcgggcg
     5581 tcgccgcgct cgcgctgctg accgccgccg agcaccgggc cgggccgatc ggctacggcc
     5641 tgctggtcct cgtcgcggcc ggcacgcccg cgctcggcgc ccggctcgcc cgggtcaccc
     5701 tgcccgcgct ctcccgccgt cggctgctcg cgctcgccct gctggccgag ggcgtcgcgc
     5761 tgatcctggc aggcctggtg ctggacttcg tcctggtcct gctgctcacg gtgctggccg
     5821 ggctggccgc cggcatcgtg atctcggccg gtcgcaacct gctcgcccag gaggtcgagg
     5881 aggcccggct cccgaaggtc accgagcacc tgaacgcggt gctgcgggcc gtcgtgggcg
     5941 ccgcactgat cgtcgtgccg ctgatcgccg ccgcctacgg gaacatcgag tacggcaccg
     6001 tcgagcccgg ctcgttcacc ttcatccacg gcggcgcggc cctcgcggtc gccaccgccg
     6061 gcctgctgac cctggtgctc gccgccgtgg tgctgctcag gaccgacgac cggcgcggca
     6121 ccgtcccgtt cggccgcgac ctggtggacg ccgtccgcgg tgcggccggt ccggtcccgc
     6181 accgcaccac cgacaccggc ttcttcatcg ccctggaggg cggcgacggc gccggcaagt
     6241 ccacccaggc ccaggcgctc gccgagtgga tccggggcaa gggccacgag gtggtgctca
     6301 cccgcgagcc cggcggcagc ccggtcggcc agcggctgcg cggtctcgtc ctggacgtcg
     6361 gcaacaccgg actgtcgcac cgcgccgagg cgctgatcta cgccgccgac cgcgccgagc
     6421 acgtcgagaa cgtcatccgc ccggcgctgg cccgcggcgc cgtggtgatc accgaccggt
     6481 acatggactc ctcgatcgcc taccagggcg ccggccggga cctcgccgcc accgaggtgg
     6541 cccggatctc gcgctgggcg accggtggtc tgctgcccga cctgaccgtc gtcctggacg
     6601 tcgacccgac cagggcccgg gagcggttca ccgaggcgct ggaccgcctg gagtccgagc
     6661 ccaccgagtt ccaccagcgg gtccgctccg gcttcctcgc cctggcggcc gccgacccgg
     6721 cgcgctacct ggtcgtcgat ggcagccagc agcccgcttc cgtcaccacc gcgatccgcc
     6781 accggctcga ccgcgagctg ccgctctccg agcaggagaa ggccgcccgc gccgagcagg
     6841 agcggctcgc ccgcgaggag gccgagcgcc gcgcggccga ggaagcgcgg aagaaggccg
     6901 aggcggaggc cgccgagcgc aagcggcagg aactgctgga gcagctccgg gccgagcagg
     6961 cggagaagga gcgcctcgcc aaggaggagg ccgaccgcct cgccgcggag gcggcgcgca
     7021 aagcggagga ggaggcccgc cgcagggcgg aggaggaagc ccgccggcgt gccgaggagg
     7081 aggccaagct gcgcgcggcc gaggaggccc ggctcgccgc cgaggccgcc gagcgcaagc
     7141 ggctcgccga cgaggcggcc gcccaggcgg agctgcagcg gcagcgtgag ctggcgcgcg
     7201 aggagcagcg ccggcgtgcg gaggaggcgc tccagcgggc cgaggaggcc cggctggcgc
     7261 aggccgcggc gctcgctgcg gcggctgccg cggcggagag cgcggccgac cgggtcgggc
     7321 ggccggtgcc gggggacgcg gtgaccaccg agctgcggat ggtcaaggac gtcgacgacg
     7381 ccacccagga gatctccgag cgggaccgcc gggcggcggt ccgggcggcg gaggaggccg
     7441 gcgcgggcgt ctccggcgtc gacgcgacgg cgaagttccc ggtcgttccc gccgccgcgg
     7501 cggacgagac ggcgaagctt ccggtcgtcc ccgctgccgc ggcggacgag acggccgtgc
     7561 tgccccgggt gcccgggacg gatcggaccg aggtgctgcc gcgggtcggg ccggccgggc
     7621 cggccccgcg cgccgggcag gaccagccgg tcgacggcac ccgggaactg ccggtggtcg
     7681 aggagccgga gcaggccccc gagccgcgtc cccggccgtc ctgggccgag gagaccccga
     7741 tggacgacct gccgagcctg accgacaccc tgctcggctc gcgcgacgag tgggcccgct
     7801 gggagcagcc cggcccggcc gggcagggcc cgcaggaccc gcgcctcgcg tacggcggcg
     7861 aggcggccgg accggccgga ccggccgagc cggaggccga cgccccggac gaccagggcg
     7921 gcaagggcaa gggccggcgc tggcgccggg gctgaccccg ggataggtag gacagcaggg
     7981 cagcaggacg gcaggacggc gggcggtgtg gccggggcgg tgctccggcg gcgccgcccg
     8041 ccgtcgtacc gggcacgtat gctcgaccgc ggggagcgga gaccgggccg ggcgtaggac
     8101 accggggcgg tccgcacgag gcagtccgta ccgagcttgg gagcagcagt ggccgtctgg
     8161 gacgacctgg tgggccagga gcgggtggtc gagcagttga ccgccgccgc ccgggcggcc
     8221 ggggcgacgg tcgccgccgg ccgcggggcc gcacccgagc cgggcggcaa cgcctcgctg
     8281 atgacgcacg cctggctgtt caccggtccg cccggcgcgg gccagaccac ggccgcccgc
     8341 gccttcgccg ccgccctcca gtgcaccagc ccggacctcg cgctcggcgg gacgcccggc
     8401 tgcgggttct gcgacggctg ccacactgtg ctggcgggca gccacgcgga cgtgaagtac
     8461 gtgcgcaccg acggcctgtc gatcggcgtc ggcgacatgc gcgacctggt gctgcgcgcg
     8521 tccagctacc cgaccggcgg ccgctggtcg gtgatcctgg tggacgccgc ccaccggctc
     8581 accgaggccg ccgccaacgc cctgctcaag ggggtcgagg agccctcgcc gcgcaccgtc
     8641 tggatgctct gcgcgccctc cgtccaggac gtcctgccca ccatccgctc gcgctgccgc
     8701 ctgctcgtcc tgcgccagcc cgccgccgag gccgtcgccg acatgctggt gacccgcgac
     8761 ggcgtcgacc cggagacggc ccggctggcc gcgctcgcgg gccaggggga catcgagcgc
     8821 tcccgccggc tggccgtcga cgaggaggtc aggacccgcc gggccgaggt gctgcggatc
     8881 ccgctggagg tcgccgacct cggcggctgc ctggccgccg cccagcgact ggtcgacacc
     8941 gccaaggccg acgccgaggc gctcgccgag acccaggacg ccaaggagac cgacgacctc
     9001 aaggccgtgt acggggcggc cgagggcggc aaggccccgc gcggcatggc cggggcggtc
     9061 aaggagctgg agaagcggca gaagagccgc gccacccgca cccgccggga gacgctcggt
     9121 gtcgccctgc tcgacctcct gggcttctac cgggacgtgc tcgccctcca gctcggctcg
     9181 accggtgcgc tggccaacga ggaccagcgg ccggccctgg agcgggtcgc gcaggccggt
     9241 ccgccggagg gcacgctgcg ccggatcgag gcggtgctcg cctgccggca ggcgctggac
     9301 cgcaacgtcg acccgctgct cgccgtcgag gcgatgacgg tcgcgctgcg ggcggggtag
     9361 ggcgcgtcct cgaacgcttc cgtccgcggg ggcggggcac gtcctcgaac gctcccaccc
     9421 gagggggtag ggcttcccgc gctaggcgcg tgtcccacct tcgagtgaac gggccgtacg
     9481 cgccgggcac acccacgtgt gaccgccggg tcgtcttgca cgctggggcc gactgcgccc
     9541 cgacgccggg gccgtcgcgt cccgtccggc accggccccc caccggtggt ccggccctcc
     9601 tcccgaggcg gtgcgtccca tggtccgttc gctcctcgtc gttcccctgc tggccgccgc
     9661 cgggggaggt gtctggctcg cgcgcggtgc cctgctgcgc tggcgcgacc tgcgggccgc
     9721 cgagacctac gagctcaccg gtgaccagcg gccgatgctg ctgcgcgcgg ccggggcgat
     9781 ggtctgcggc gtctgcgtca cggcgctgac gctgctcacg gccctgggga cgttcggcgt
     9841 cctggggtcc tcggcgccgc ggtccggctc cgccgagttc ggcgccgact ccgacgccgc
     9901 ggcggcggac ggcacggacg gtgaggccgc cgcacggcag gctgccccgc cggtggccga
     9961 ggccgaggcc gcgtccgcca ccgccgtgtc cgcgaccacg ccggccgccg cgccggtggc
    10021 cagccggttc gacagcgtcg gccaccccgc cggcggcgag ctgctgcagt ccgccgtgct
    10081 cggcccggac gggcacccgc gcaacgtccg ggtctggctg cccgcccagt acgccaagga
    10141 cccgaacgcc cggttcccgg tggtcgtgat gcacgccgcc accccgcgca agaccgccga
    10201 cgccgaagtc cccgacgtct tcgagggcct cggctccgcc gtccagaccg gcaaggcccg
    10261 cccgttcatc ctggtcgccc cggaggcgcc gaacggcacc gcgcacccct gcgagctggt
    10321 cgccgccgcc ccgcaggcca tcgccgacga cgcggcgctg cgcaccacca tcgccgcgac
    10381 cttccgcacc ctgccgcccg gcccggcgtc ctggggcacg ctcggcgtcg agggcggcgc
    10441 gccctgcgcc gcggccgccg ccctggcccg gcccgacctg tacggcgcgg ccgcggcggt
    10501 ctccggccgg tacgacaccg ccgcgctggc cctgacgggg gcggaggcac ccgtcggcgc
    10561 cgcgcccaag ctgctgctgg ccgcggccaa ggccgacgcc gccgggctgg acgcggcccg
    10621 caagctccag gccgcgctgc gcgccggcac cggcgcggcg gcccgcgccg acgtgcggat
    10681 ctccgagaac gtgcaggact acacggcgga ccgggagcgg ctgcggctgg tccggcaggc
    10741 ggcgcagtac ctggccgaga cgctggccaa ggtgtcctga gcaggcctcg gcagcggctg
    10801 agaagcaagt gctgagcagc cctgagcagc cctgagcagg ccggatgcgg gcacccggcg
    10861 ggcgttacgc tcgccgtacc cgggcaccgg cggcggccgc gccgtggaac ccgaggtcag
    10921 agggggagca gatgcaggcg gaacgggaac gggaacggga gcgggagcgg gagcgggagc
    10981 ggatgagggc ggagcggggc cgacgccggc cggcggtggc ggcggtgctg gccgccgggc
    11041 tgctggtcgg cgggtgcagc ttcagcacct ccacgccgcg cgcttcctcc tccgacaccg
    11101 tcgcgccggg ctccccgtcc gcgctgggct ccccgtccgc gacggcctcc gcggccgacg
    11161 cccggccggg ggtcacgccg ctggagccgc tcccggcggc cgtccccgcc gccctggcgc
    11221 cgtactacgg gcagcggctc gcctggcagc cctgcgacga gggcttcgag tgcaccacct
    11281 tcacggtgcc gctggactac gaccacccgg cgggcgggga cctcaccctg tcggcggtcc
    11341 gcgcccccgc cgtcccggcc ggctccggta cgggcgccgg atccggccgg ctcggctcgc
    11401 tgctgctcaa ccccggcggc cccggcggct cggcggtcga ctacgtggag gccgtcgccc
    11461 ggacgtacga cggtggtgtg cgggcccggt acgacctggt cggcgtcgac ccgcgcggcg
    11521 tcggccgcag cgccccggtg acctgcctcg gcggcgagcg gatggacgcc tacagcgccg
    11581 ccgacatcac ccctgacgac caggccgaga tcgacgccct ggtcgccgcc gacaaggagt
    11641 tcgcggaggg ctgccgccag cgggtcggcg accggctcgg ccacctgagc accgtcgaga
    11701 ccgcccgcga cctcgacgtg ctgcgcgcgc tgctcggcga cgagaagctc aactacgtcg
    11761 gcaagtcgta cggcaccttc ctcggcgcca cctacgccgg gctcttcccg acccgcaccg
    11821 gccggatcgt gctggacggt gccatggacc cgtccctgga cgcgatcacc ggcaaccgca
    11881 cccaggccgg cggcttcgag accgcctggg cggccttcgc ccaggactgc gccaagcgcg
    11941 aggactgccc gctcggccgg accgagcagc aggccggcga gcagctcacc gccctgttca
    12001 aggcgatcga cgcccagccg ctgaccaccg ccgacggcgg ccgccggctc accgaggccc
    12061 aggccaccac cggcgtcatc caggccatgt acgccgactt cctctggccc aggctgcgca
    12121 ccgcgctcgc cgacgccaag accggcgacg gcagcggcct gctcaagctc tcggactcgt
    12181 actacgaacg cggctcggac ggctcgtacc ccaacctgat gttcgccaac atggcggtga
    12241 actgcctgga cctgcccgcg ccgttcaccg gccccggcga cgtccagcag gcggtggcgg
    12301 acttcgagcg gacctcgccg cggttcggcc gcgacatggc gtggatggca ctgacctgca
    12361 cctactggcc ggtgaaggcc accggagcgg cacacaccat ccgggcggcc ggcgccgcgc
    12421 cgatcgtggt cgtcggcacc acccgcgacc cggccacccc gtacgcgtgg gcgcagtcgc
    12481 tggccgggca gctggagtcc ggccggctgc tgacctacga gggcgacggg cacaccgcgt
    12541 acggccggca cgacgcctgc gtcgacggcg cggtcaaccg ctacctgctc ggcggcgagc
    12601 cgccggagca ggggaagcgc tgcggcgcgt aggctcccgg ccccccgcca gcccctgtcc
    12661 ggcccccgct ccgcgcccgc ccggcccccg ctccgcgccc gcccgggaac ccgttacgga
    12721 tcacccgcga acctgtgtag actggcccgc gttgcaaccg cgtgttgcag cggtgccgcc
    12781 ttagctcagt tggccagagc aacgcactcg taatgcgtag gtcgcgggtt cgaatcccgc
    12841 aggcggctca gtgaaggccc aggtcaggta gcccatgacc tgggcctttt gccgttcctt
    12901 gatgtgtaag caggtatcag tgacgcgcta caagatcgct tgcgtgagcg atgcgtgagc
    12961 gcgggtgttg atgggtgcgt ttctcttgag gtgacaggcg tgtccgtggt tgttgttggt
    13021 tcgttgccgt agcggagttg atcgttctgc tcggtgaggg ggctggtggg ctgcgaagcg
    13081 gtggagcgtg accaggatga gcaggtggtc gagcaggtcc acttcgacga ggccgctctc
    13141 gaggagctct tgtggggagc ggcctcgagg gacgggggcc agttgggagt gaacctgctg
    13201 aagcacacat gcagtcgacg agccggttct aggctggagc cctcaccttt caacgcgggg
    13261 tctcagagaa ggcccgacca ccccggtggt cggggcgtct ccaactcttc ggccaacctg
    13321 gaggcgctga tcatggatgc aaaccgagtc ctcgaagcgc tcgaggcggg cgagttcgac
    13381 ggcgtcagcc acacctatca gccctatgac ggctacggga accagaccca tcaggttgcg
    13441 atgagcgtct ccggtggcac catcgaggtc gccaagacca ccagcgggaa gttcttcgac
    13501 gggaaggaga acacccgcta ctccaagacc agcactgact atctgaccgg catggatgcg
    13561 gtgggcttca tcgcccagcg gccgtactac ttctcgcagg ttcgccccga cctcttctag
    13621 tactgcaatc acagttatgg ggtgtgacct cggcgtttgt agtggctgag gcgggctcgg
    13681 gtctggctga ggcgtcgcca ccatgaccag tgcagatgat gcgtcgggtc nnnnnnnnnn
    13741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15361 nnnngacggg caggacgtct ctgacgacca ggaacgggaa gagcggcgac gaatccggcg
    15421 ccggcgcaag ctccggctga aagccgccct gctcggacgc tccagaggcg gacagaccag
    15481 caagatccat tgtgccggcg accggaagtg ccgcccgctg gcgttcatcc tgaccgaggg
    15541 acaagccgcc gacagcccgc agttcatccc cgtgctgaag aaggtccggg ttcgggtgcc
    15601 ggtcgggcgt ccccgcaccc ggcccgacgc tgtcgccggc gacaaggcct actcgtcccg
    15661 cggcaaccgc gcacacctgc ggaatcggcg aatcaaggcg gtcatcccgg agaagaagga
    15721 ccaggctgcc aaccggaaga agaagggcag caagggcggt cggcccgtcg gccacgacgc
    15781 cgagctctac aagcaacgga acaccgtcga gcgcctgata aacaagctga aggcctggcg
    15841 cggcatcgcc acccggttcg acaagacccc cgagagctac ctcgccggcc tcaaccttcg
    15901 agcctcgatg atctggatcg acgatctcct gccgaccatt gactgatcac gacatcacac
    15961 aggccctaag agtggctaac acattacttg gacgcgcctg taggtgatca cgcagcaggc
    16021 gagcgcctcc aggccgcata cgatcaggcc gccgccgacc agctcgcgtt cctcgcccaa
    16081 cgccagccca agcagcaagc ccgtaacacc tgcacgctgc gggcggccac cagttggtgg
    16141 tcgcccgcag cgtgttctct cagtccttga gcgcggtgtc caggtatgcc tgcactggct
    16201 cgaagacccc gtacgggacg tattcaggga tctctgcaag cgccacccac gccagtgcgt
    16261 ccagctctcg tgggtcaccg acagcagcgg tgccgctgac gatcttgcag accgtgtacg
    16321 acatccaccg gccagtctcc gggtggacgc gctcgccgag gatcttgatg gcggccacgt
    16381 tcagccccgc ctcctccgcg gtctcgcgga cagccgcttc ctcgggagac tcgccgggct
    16441 cgatcttgcc tgccgggaac tgccacgaga gctggccctc gctgacccgg cgccggacca
    16501 tcagcacccg accctctcgg gtcacgatcg cggcagcgac acctggccgt ccgtctgaag
    16561 ccgggagcat cggctacttt ctctccgccg ctgaggccgc cacggggcgg agcaggtcga
    16621 ggacgtgagt ccagttgtac ttgtcgcggc ccccgccggc cttgggcttg tgggggacgt
    16681 agtcaccgat caagacgccc atcgaccgga gccgggccag gctctccgcg tacgcggggt
    16741 gggcggcctg ggcggagttg acgtagggct ggacggccac ggggatgccg agaccgtagg
    16801 cgtcgcaaag gatgccgagt gcgagggtgt cggagatgcc ggcggcccac ttgttgatgg
    16861 tgttgaacgt agccggggcg accgcgatgg cgtcggccgg cggcagcggt tgggggatgc
    16921 tgggggtgcg ccaggcggag cggatcgggt agccggtctg ggcttcgatg gcttcctgat
    16981 ctatgaatcc gagcccgctc ggggtcgcga tcacgccgac tccccagccc tcgacatggg
    17041 cagcggtgat cagctcgccc actccgtcgg cgatgcccga cgcgcagacg acgacgtaga
    17101 ggaacggctc gcggtgctcg gtcaaacctg gactcccaac tcctggcaga aacggcgaag
    17161 ttccgggacg gcgccgcgcc ggtcgcgagc agccatgtca ccggccagct caagcacgct
    17221 gggccgtcgg cggatgtcct ccgaggcaca gctctccgcg atcctgagcg ctttgtatcc
    17281 ctcggccagt ctgccctgct ggctgtaggc ccgtgcagcc tccacccaca gtgccgcccg
    17341 gcgctcgggg accgggatac gcctgcgcat cagcggctgg gcggcttcta acgccgctcc
    17401 ggcgtcgccc agaacgaccg aggcgctcac cgagtggagc gcgacgttgg tcggactgaa
    17461 gtttgcccag gcttcggggc tgtcgaggtc gacgtagcgc gcgacctcct gggcctcggt
    17521 gaggaactcg gcggtcgtgg cgcggtcgcc gccggcgctt gcggccgtca ccccgcgaag
    17581 gagcatgagc cccagcgcgg cgaggtactc gggcgggcgc cggtcgtagc tgcggagagc
    17641 tggtcggcgg tgtgccggat gagggttacg gcgggcgcgg tgtgccggtc gcgcgcgagg
    17701 acgtgcgcct ggacgcggac gctggaggcc gtcacgacgg ggtcggcgct ccgttcggcc
    17761 tcggccatgg cacggccgac cgccagccag gcgttgccgt ggtcgccgag cttgagcagc
    17821 aggctcaccg cggtctggta ggccgtcgcg aggaggccgg acaggacctg gtcgccgcca
    17881 cggacggcgt cctgagcctg gcgaaggtcg gcgatcaacg acggcagcgc gccttcgagt
    17941 tcggcgtacc ggcaggtgta gaagagcctc cgggcctggg agagccgggc cgcgagtgcg
    18001 gcctggggtt gtggcgcgtg ctcggctgga acaggtccag gcagcagcgc ctggaccagc
    18061 tctatcccca cgcggggacg gggcgtcggg gtcgcgagcg cggcgacgct cgcggccagg
    18121 aagttgcgac ggtgcatgtc gtccgtcctg ctgtccgcac tggccaggcg gtcggcgccg
    18181 acgaggtggt ccatgccctc cgatcagaag gccgccatcg tcctgtccat tccggcgggc
    18241 gagatcaccg ctgccgaggc cgccaggtcc gcgggagtca ccgggcaggc catcagcaac
    18301 tggaagcgcc gcttcatcga ggccggttgc ggcggacttg aggcgacctc ggacccgcag
    18361 gccagtcgag aggccgaact ccgtgaggag atcgcccggt tgaagggtgc tctgggcgac
    18421 tcctacctgc agctgcaggc catccgccag tcgatgcgcc tgcggccggg cccgcccgcg
    18481 cccccctcgg cgggcgcggc aggggcgagg cgcacgcgct cggccaggcg cgtctcaacg
    18541 gcgtggtgcc ggcgcagcgt tccgcctccg gggcctgacg gcccggtccc ggcgctccgg
    18601 tgcccccgat gcggcgccgg agcggtggcg tttccggccc gcgcgtccgg ggttgcgccc
    18661 gaggtgggtc ctggcgggtc ctggcgagtc ctggccgacc gggttgctca tccgatcatc
    18721 aaaggtatct gctcggattc cgcgccattc tggccgatat ttttcctctt tattatccga
    18781 caaaccttga cgcttgtgaa tcttttccaa aattcctcgc ttcgccttcc aggcgccgtt
    18841 agtatcggaa cgattgcttt cggtgaccgt tcggtaccgg accgcgaagg gggtagccgt
    18901 gagtgggaag ctgcgtgccg tgctgcgtcg tgtcgcctac ccgaccctgc tggtcaccgt
    18961 cgtgtcgata tcggtcgccg ccctgcgctg gcgctgggac ctcgggcgga ccagcctgct
    19021 cttcctgctc ggcaccatcg gctgtctgac ggccctggaa cagttgattc cgtacgaacc
    19081 tgagtggcag ccgaccatcg gcgaatgggg ctggtacggc gtctacttcg tcctgacgat
    19141 gatcggcggg gcgctggcgc agctgccggt gacggccgct gtcgggtggt tggcgccgcc
    19201 gcatccgacg ctgccgctct gggcggagat cccggcggcg ctgctgctgg gctcgctggc
    19261 caactacctg gtgcaccgct ggagccactc caacccgtgg ctctggcggc tgcacggggt
    19321 gcaccacgtg cccgggaagg tcaacgtcgc caacaacggc gtcaaccacg tcgtcgacgt
    19381 gctggtcacc cagggaacgg tccaactctc cctcgcgctg gcgggtttct cggcggagtc
    19441 ggtgttcgtg gtcggtctct tcgtggtcgc ccagggctat ttcgtgcacg ccaacgtcga
    19501 cgtccggctc ggcgtgctca accatgtctt cgccggcccg gagcagcacc ggctccacca
    19561 cagcgccgac ctggcggagg ccggccactt cggctccgac ctctccgtct gggaccacgc
    19621 cttcggcagc ttcacctggc ggcccggccg ccggccggcc gtggtggggc tgcagcaccc
    19681 gtccgagttc ccgcggacgg ccgaggtgat caccagtcat ctccagccct ggcggcgacc
    19741 ggtgcgcccg gtccgggtcg acgactcccc ggtctgacgg cccgccggtc ctccccgccg
    19801 gtcctccccg ttgtgccggc ccgggcgggc tgccccgccg aagtccatcc gtccgtgctc
    19861 tccccgttcc ctcggcctgc ccgccccggc ccgccctccc cggcctgccc ggagccgggc
    19921 cacggccgcc gtccccatgc ccgcgcggcc ctccctcgcc cgtgccgcgc gcgcgaacgc
    19981 agcgacacaa ggactcgacc atgacggatt catgcctcgc cgcagcctcc ggcccttctg
    20041 attccccggc cccctccgac accgcccgtc ccgcccgccc cggccgaccc gcttccaccg
    20101 cccggagtgc cccggccgcc cccgccgccc cggccgccga cggccccgag cggatcgcga
    20161 tcatcggcat cggctgccgg ctgccgggcg gggccaacga ccaccggtcc ttctggcaga
    20221 acctggtcga cggcaaggac tgcatcaccc cgaccccacg cagccggtac gacgtggcca
    20281 ccctgggcag ccgggacaag gccaggccgg gccggctggt cggcggccgg ggcggctaca
    20341 tcgacggctt cgacgagttc gacccggcgt tcttcgggat cagcggccgc gaggccgacc
    20401 acatggaccc gcagcagcgc aagctgctgg aggtggcctg ggaggcgctg gaggacggcg
    20461 ggcagaagcc ggccgagctg gcgggccgcg aggtcggcgt ctacgtcggc gcgttcacgc
    20521 tggactacaa gatcgtgcag ttctcggacc tctccttcga gaccctggcc gcgcacaccg
    20581 ccaccggcac gatgatgacg atggtgtcga accggatctc gcactgcttc gacttccgcg
    20641 gccccagcgt ctccctcgac accgcgtgca gctcctccct ggtcgccgtc cacctggccg
    20701 cccagagcct gctgcgcggc gagaccgacc tcgcgctggc cggcggcacc ctgttgcaca
    20761 tcgcgccgca gtacacgatc gccgagacca agggcggctt cctctccccg gagggccgct
    20821 cacgcacctt cgacgcctcg gccgacggct acgtccgcgc cgagggcgtc gccgtggtgg
    20881 cgctcaagcg gctctccgac gccctgcgcg acggtgaccc ggtccatgcc gtcgtcatcg
    20941 ggagcggggt caaccaggac ggccggacca acggcatcac cgtgcccaac ccggacgccc
    21001 aggtcactct gatcgagcgg gtctgcgccg aggccgggat cgcacccggc agcctccagt
    21061 acgtcgaggc gcacggcacc tccaccccgg tcggcgaccc gatcgaggcg aacgccctgg
    21121 cccgggcgct ggcgatcggc cgccgccccg gcgacgcctg ctacgtcgga tcggtcaaga
    21181 ccaacatcgg gcacaccgag tccgcctccg gcctggccgg gctgatcaag tccgcgctgg
    21241 cgctcaagca ccggctgatc ccgccgcaca tcaacctgga gacgctcaac ccggcgatcg
    21301 acgcggccgc gctgccgtac cggatcccga ccgagccgac cccgtggccc gcgcaccagg
    21361 gcccggccag ggcgggcgtg aactccttcg gcttcggcgg caccaacgcc cacgtgctgc
    21421 tggaggccgc ccccgagccc gagcccgagc ccgcgcccga gccggagccc gtcccggcgg
    21481 ggcgtcggcc gcccgggtac accgtgctgc cgctcaccgc ccgggacgcc gccgccctgc
    21541 ccgagctggc cgccggcatc cggggcgagc tggccggtgt ccgcggcggc gtcccggccc
    21601 ggctggccga cctcggccac accctggccc accgccgcca gcacctcgac gcccggctct
    21661 ccgtggtgca cgactcccgc gagtcgctgg acgaggcgct ctccgcctac ctgcgcggcg
    21721 agccgcaccc ccgggtgctg accggccggc gccgcgaggc ccggcaccgc cggctggcct
    21781 gggtcttcac cggcacgggc ccgcagtggt gggcgatggg ccggcagctg ttcgaggccg
    21841 agccggtcta ccgggaggcc gtcgaggcct gcgccgggca cctcgccgag ctgaccggct
    21901 ggtccctcgt cgaggagctg gccgccgacg agacacactc ccggatggcc gagacctggc
    21961 tcgcccagcc cgccaacttc gccgtccagg tcggcctggc ggcgctctgg cgcagccgcg
    22021 gcgtccaccc ggacgcggtc gtcggccact ccaccggcga ggtcgccgcc ttctacgagg
    22081 cgggcgtcta cgacctggcc gacgcggtca gggtggtggt gcaccggagc cgcctccagc
    22141 agaagctggc gggcaccggc ggcatgctgg ccgtcgcgct ccccgaggcc gaggcggtcc
    22201 gccggctccg cccgtacggc ggcgcggtct cggtggccgc ggtcaacagc cccgcctcgc
    22261 tcaccctcgc cggggatacg acggtgctcg cggagctggc cgcggcgctc accgccgagc
    22321 aggtcttcgc ccgcccgctg gccgtcgaag tgccgtacca cagcgcccgg atggatctga
    22381 tcaaggacga gctgctggag tcgctggccg acctcagggc ccgccccgcc cgggtgccgc
    22441 tctacctgac cggccgggag ggcatcgcac acggcaccga gctggacgcc gcctactggt
    22501 ggcgcaacgt gcgcgacggc gtccgcttcc agcaggcggt ggagcggctc gacgacgacg
    22561 ggttcagcct cttcctggag atcgggccgc acccggtgct ggggcgcgcg atccaggaga
    22621 cggtggcggc ccggcccgcc gacgccgacc gccccgaggt ctgcacgctg gcctcgatcc
    22681 gccgccagga ggacgagcag gcggccttcg ccacctcgct ggccgccctg cacaacctcg
    22741 gggtcgagct cgactggtcg gtgctccagc ccgccgggcg gcccgtcccg ctgccgcgct
    22801 acccgttcag gcgggaccgg cactgggtcg aaccccggtc ggtcgagcag gtccggcagg
    22861 gccggctgga ccacccgctg ctcggccgcc gcctcgccgg tgccgagccg gcctgggagg
    22921 cccgcccgga cgccgaggca ctgccctacc tggaggacca ccgcatccag ggccaggtgc
    22981 tcttccctgc cgccggctac ctggagatgg ccgtccaggc ggtccgcgcg ctgaccggcg
    23041 gcgccgatgc cgcgctggcc ggcatcgagc tgcgcaaggc gctgttcctg ccggacgacg
    23101 agagccgtgc cgtccggttc acgctctccg ccgagaacgg cgccttcacc gtcaccacca
    23161 ccggccccgg cgaggggcag gagcgcaccg tccacgccgc cggcaccgtc cgccccggcc
    23221 agcgccggcg ccgccccggc caccggctgg acgccggcgc cgtccgcgac cgtgccgtcc
    23281 ggcacctggc cggccccgac tgctacaccg cgctggccgg gctcggctac cactacggcc
    23341 cggccttcca gggcatccac gaggtctgga tcggcccggg cgaggcgctg gcggccgtcc
    23401 ggccgacggc ggcgatcgcc gggcagggcg ccggccacca ggtgcacccg gtgctgatgg
    23461 acgccttctt ccagaccctg ctgacacccc agctgctggt ggaggcccag gccggcaccg
    23521 ggatcaggct gccgttggcc atcgacgagg tccggctgga cgccgtgggc gagcgcccgc
    23581 tctgggtgca cgccaccgtc acccgcgacg gcggggacga gctggtcggc gacatcgcgg
    23641 tctacgacga ggacggcgtg ccgctcggcg ggatcaccgg tttccgggcc gccgacgtgg
    23701 agaaggcctc caccgccgtc ggcctcgcca ccatcgacgg ctggctcgcc gagcccgtct
    23761 ggacggcgct gccggacggg ccggacacct ccgagccgct gtccggacac cccgaccact
    23821 ggctgctcct cgccgacgcc cagggcgtcg ccgaggagct cgccgcccgg atcgcggccc
    23881 gcggcggcga ctgcaccctc gtccgcccgg gcagcgacta ccggcccgcc ggcgacggac
    23941 ggccggccac cgtcgacccc ggctccggtg aggacctccg ccggctgctg tccgaccggc
    24001 gggccgcggg cgccgccgac ccggccgtcg tcgtccacct ctggaacctc gaccggcccg
    24061 cgctggccgg ggcggaccac gccaccgtgg ccgggcacac cggcgccggc gcgtacagcc
    24121 tgatcgcgct ggccgccctg ctgcccgccg aactgcccga cgcccggctg cacatcgtca
    24181 cccgcaccgc ccaggccacc acgcccggcg agccggtcga gccgctcggc gcccccgcct
    24241 ggggcatcgg ccgggtactg cgccaccagg agctgcccgg ccaccccggc aagctggtcg
    24301 acctcggccc ggccggcgac cccgccgagg aggcggccgc gctgctgtgc gagttcgggc
    24361 tcgccgacga ggacgagatc gccctgcggg ccggtcgacg gctgaccagc cggctgcgcc
    24421 ccgccgaggg cctgaccggg ccgctgccgc ccagcctgcg cccggacggc gcctacctgg
    24481 tgacgggcgc cttcggggcg ctcggccggc tgctctgccg caccctcgtc cgccggggcg
    24541 cccgccggct gatcctggtc ggccgcagcc cgctgccgcc gcgcgagcag tggcgcggcc
    24601 tcgacccggc gagcccggcc ggccgcaaca ccgccttcct gcgcgaactg gaggcgctcg
    24661 gcgcccagcc cgtcccggtg ccgctggacg tcaccgacga ggcggcgctg ggcgcctggc
    24721 tcgccgggta ccgggcgctg gagtcgccgc cgatccgggg cgtcttccac ctggccgggc
    24781 aggtccgcga caccctggtg ccggacctgg gccgcgaggt gttcgacgcc gtccacggac
    24841 ccaaggtgct gggcgccttc gccctgcacc ggcagctcgc cgacgagccg ctcgaccact
    24901 tcgtgctgtt cgcctcgatc gcctcgctgc tgaccaccgc cggccagacc aactacgcgg
    24961 cggggaacgc cttcctggac gcgctggcgc accaccgccg ggccctgggc ctgcccgcgc
    25021 tcagccttga ctggggcccg tgggccaccg ggatgatcga ggagctcggc ctgatcgacc
    25081 actaccgcaa cagccgcggc atgagctcgc tcgcgcccga ggccgggatg gccgtgctgg
    25141 agcgggtgct cggccaggac cgcgcgcagc tgctggtcgc caccgtggtc gactggccgg
    25201 tcttcctctc ctggtacccg gccccgccgc cgctggtcgc cgagctggcg gccgcggccc
    25261 gggcgagcgc cccggcgccg cagcacggca gcctgctgga ggcgctgcgg gcggccgggg
    25321 aggaggagcg ccgggcgctg ctcaccgagc ggttcaccgc actggccgcc gccgtgctgc
    25381 gggtgcccgc cgagcaggtc ggaccggcca ccggcctgag cggcctcggc ctggactcgc
    25441 tgctcgcgat ggagctgcgg gcccggctca acaccgagct cggcaccgcc ccgccggtgg
    25501 tggcgctgct ctccaacgcg ccggtcgccg agctggtcga ccggctgcac gcgggcctcg
    25561 ccgagctgat cgaggaggac ggcacgggcg ccgccggcgc cggggtcgtc cggtacgagg
    25621 acgagtcgag ccatccgctg acgcagaacc agaaggcgct ctggttcctc aagcagctca
    25681 acccggacgg cttcgcctac aacatcggcg gggcggtcga ggtccgggtg gagctggagc
    25741 cggagctgat ggccgccgcc ttccgggcga tggtcgagcg ccaccccagc ctgcgggcca
    25801 acttcgtgct cgacggcggc cgggccgtcc agcgggtcgc cgccgcggcc gagccggact
    25861 tcggggtttt cgacgtcgag ggactggact ggccggaggt ccacgacctg atcgtccgcg
    25921 agtaccgcga gccgtacgac ctggagcggg acccgctggt gcggttccgg ctgttccggc
    25981 gcggcccggc ccgctgggtg atcatgaagg ccgtccacca catcatctcg gacgcgatct
    26041 ccaccttcac cttcatcgag gagctgctcg ccgtctacga ggggctgcgg cggggccggg
    26101 cgcccgagct gcccccggtc ggcgcccgct acctcgactt cctcaaccgg cagaacgcgt
    26161 tcctggccgg ccgcgaggcg ccgcggatgc tcgactactg gcgctcgcac ctgcccgccg
    26221 aggtgccggt cctcagcctg cccaccgaca agccgcgccc ggcggtgcag acgcacaacg
    26281 gcgcctccga gttcttcgtc ctggacgagg agctgagcgc ccgggtgcac gcgctggccc
    26341 gcgagcacaa cgtcaccgtc ttcatggtgc tgctcagcgc ctactacctc ctgctgcacg
    26401 cctactcggg ccaggacgac atcgtcgtcg gcagcccggt gaccggccgc accgacgagg
    26461 agttcgccgg cgtctacggc tacttcgtca acccgctgcc gctgcacgtc tcgctggccg
    26521 gcgcgccgac ggtggccgag ctgctcgcgc aggtccgcac caccgtgctg ggcggcctgg
    26581 acaaccagga gtacccgttc gtgctgctgg tggagaagct cgggctccag cacgacccga
    26641 gccgttccgc ggtcttccag gcgatgttca tcctgctcca ccacaaggtg gccaccgaga
    26701 agtacggata ccgcctggag tacatcgaac tcccggagga ggaagggcag ttcgacctca
    26761 cgctgtccgc ctacgaggac gaggccgagc gccgcttcca ctgcgtcctc aagtacaaca
    26821 ccgacctctt cctgccggag accacggccc gcctcgcccg gcactacgtc aacctgctgg
    26881 acggcctgac ggcggccgcc gccgaccacc cggccaccgg gctggagctg ctcggccggg
    26941 aggagcgcgc cctggtgctc cggcggtgga gcggggccga acggcgggtc gcgcacgagg
    27001 agccggtgca cgagctgatc ctgcgggccg ccgccgagga cccgtccgca cccgcggtcg
    27061 ccgccccggc cgagtccggg ccgaccgcgc ggatggacta cggcgagctg gccgggcgct
    27121 cccggcgggc ggccgcccgg ctgcgggcgc tcggggcggg gccgggctcg gtggtggggc
    27181 tctgcctgga gaagtcgccg gagctgatca ccgccctgct ggccgtgctc cgcaccggtg
    27241 cggcctacct gccgctcgac ccgggccacc ccgccgaccg gctggcctac atggtggagc
    27301 acgccggggc cgggctgctg atcggcgacc cggagcggct cgccgggctg cccgcgcggg
    27361 tcgtcgcacc ctccgaactc gaccggccgt ccgcggggtc cgaggcgttc gaggcgttcg
    27421 aggacgcgcc ggccgacctc gacgcccccg cgtacgtcat ctacacctcc ggctccaccg
    27481 gccgccccaa ggcggtgcgg gtctcccacc gcaacctcgc ctcggcctac caggcctggc
    27541 gcggcgagta ccggctggag accgacgccc gggtccacct ccagatggcc ggcacctcct
    27601 tcgacgtctt caccggggac gtggtccgtg cgctctgctc gggcgccacc ctggtgctgg
    27661 tcggccggga gctgctgttc gacaccgccc gcctgtacga ggtgatgcgc accgagcggg
    27721 tggacgccgc ggagttcgtc ccggcggtgg tccgcacggt cgtcggccac tgcgagcggt
    27781 ccggcctgcg gctggacttc atgcggctgc tggtcgtcgg ctcggacgtc tggaaggtcg
    27841 aggagtacca gcggctgcag gcgctctgcg gcccgcggac caggctggtc aactcctacg
    27901 gcctgaccga ggccaccatc gacagcgcct acttcgaggg cccggccgac gggctggagc
    27961 ccggccggat ggtcccgatc gggcggccgt tccccaacag cgccttctac ctgctggacg
    28021 agcagggccg gcccgtcccg cccggcgtgc cgggggagct gtggatcggc ggctccgggg
    28081 tggcgctcgg ctacgtcggc gacgaggagc agaccgcccg gcgcttcgtc accctgccgg
    28141 tcggcgggga ggacggcacc gagccggtcc ggctctaccg caccggggac ctcgcccgct
    28201 gggacaccgg gggcggggtg cacctgctcg gccgggcgga ctcccagatc aaggtgcgcg
    28261 gccaccggat cgagctcggc gagatcgaga cccggctcgc cgaatggccc ggggtggagc
    28321 gggcggtggt caccgtccgg ccggacggga gcggcgacag cgtgctctgc gcctactgcg
    28381 tgccggcccc cggcgaggcg ctggaccgcc gggagctccg ccaccacctg gccggccacc
    28441 tgccgacctt catgatcccc gcccacttca ccgagctgcc cgcgctgccg ctcaccccca
    28501 acggcaaggt ggacgtcgcc gcgctccccg ccccccgggc ggacgccgcc gggcaggccg
    28561 ccgaaccgcc ggtcaccctc tacgaggtcc ggatggccga gcactggcgg gcgctgctgg
    28621 ggatcgggga gcccggcctc cagcacgact tcttcgagtg cggcggcagc tcgatcaagc
    28681 tgatcgagct gatccacggg ctgcagggag agttcaacat cagcatcccg gtgagccaac
    28741 tgttcagggt gaccaccctg cacgggatgg cgaagacgct ggagcacatc atcaccggcc
    28801 ggatcgaggg cgcccagccg tacctctggt tcaaccgtga gcagcagcag accctcttct
    28861 gcttcccgcc ggccggcggc cacggcctgg tctaccggca gttcgcggcc cacctgccgg
    28921 agtaccggct ggtcgccttc aactacgtcg cgggcgacga caaggtcggc cgctacgccg
    28981 acctgatcgg gaccatccag ccggacgggc cctgtgccct gctcggctac tcgctcggcg
    29041 gcaacctcgc cttcgaggtg gccaaggagc tggagcggcg cggccgggcg gtgcccaacg
    29101 tcgtgatcat ggactcgcac cggatcccgg agtccttcac cctcggcgac gagcacgtcc
    29161 gggccttcga gcacgagctc gccgagcacc tccagcggca caccggctcg gacatcctcg
    29221 cccaggagac ccgcgaacag gcccgggact acctgcggtt ctgcagccgg acgcccaacc
    29281 tcggggtgat caccgcgctg gtcagcgtga tctccgacga cgccaaggtg gccctccacg
    29341 cggccgggca gcacggcgcc tggcacggca gctcggccac cgggacggcg gtgttccggg
    29401 gcttcggcac ccatgccgag atgctcgacc acgggtacat cgagcgcaac gccgggctgg
    29461 ccagggacat cctcgccggg ggtgccgtcc atgcgtcctg aaaccacgga cccccgggcc
    29521 gcgcaggccc cggccggccg tcccgaggcc gccggcaccc ggctgccgcc ccccggcagc
    29581 cccccacgag aggcggacct ccccatgctc cggcagcacc ggccgctggc ctaccccttc
    29641 gagccactcg gcctcgaact ccacccccgg tacgccgagt tgcgtgatca gccgctggcc
    29701 aggatccggc tgccctacgg cgacggcgcc tggctggtca cccggtacga ggacgtccgc
    29761 acggtgctcg ccgacccgcg cttcagcctc gccgaggcga tgggccagga ccagccccgg
    29821 atgcggccgg tcgcccgcac cggcgccggc ctcttctcca ccgagccgcc cgagcacacc
    29881 cggctgcgct cgctggtggc gcgggagttc agcgcccgcc gggtcgagcg gctgcgcgcc
    29941 cgggccgggg agctggccgg ggagctggtc gacgccatgg tcgcggccgg tccgccggcc
    30001 gacctggtcg aggacttcgc catcccgatg ccgaccacca tcatctgcga ggtgctcggc
    30061 atccccgccg aggaccaccg gatgctctgg cactgggccg agacggtgct ctccgccgtc
    30121 acccccggcg aggtgctcgc cgaggagggc cgggcgttca tcgcgtacat ggccggggtg
    30181 ctggacctgc gcggccgcga gcccggcgag gacctgctga cggtgctcgt ccgggcctgc
    30241 cgcgagcagg gcctgatcac ggaggaggaa ctgctctcga tcgcctgcga cctgctgatc
    30301 gccggcttcg tctccaccac caaccagatc ggcaacttct tccaccaact cctggtcaac
    30361 cccgaggagt tgcaccgcct ccgggagaag cccgagctga tcccgaaggc cgtcgaggag
    30421 ctgatgcggt acgtcccgct gctcaccggc ttcagcctgc cccggtacgc cacggccgac
    30481 gtcgagctgg gcggggtcgt cgtccgggcc ggtgacgcgg tgatgatcgc caccgccgcg
    30541 gccaaccgcg acccggacgt cttcgaggag ccggagcgcc tcgtgctgga ccggccgggc
    30601 aacccgcacg tcggcttcgg ccacggcgtg cactactgca tcggcgccca cctggcccgg
    30661 ctggagctcc aggtggccat cgggacggtg ctggaccggc tgcccggcct gcggccggcc
    30721 gtccccgagg acgaactgaa ctggaaggcg gacgccatgg tcaacggcct gcaggcgctc
    30781 ccggtggcgt ggtgacggac cgtcaggaaa tgccaaggac gacgaggaag gccagggaat
    30841 tggcacggga aacaccgaag gggcgccggg agtcgatgat catcgtcggc ggcggcctcg
    30901 gcggcctctc caccggctgc tacgcccgga tgaacgggta ccgcacccag atcttcgaga
    30961 tgcacgagat ccccgggggc tcctgcaccg gctgggaccg cagcgacttc accttcgact
    31021 ggtgcatcag ctggctgctc ggcaacggcc cgggcaacga gatgtaccag atctggctgg
    31081 agctcggagc cctccagggc aaggagatgc ggcacttcga cgcgttcaac atcgtccgcg
    31141 gccgggacgg cagggcggtc tacttctact ccgaccccga ccggctggag gcccacctgc
    31201 tgggcatctc cccggccgac gcggccccga tccgggagtt ctgcaacggc atccgcacct
    31261 tccgcaaggc gctggccgtc tacccgttcc tcaagccggt cgggctgatg ggccgggtcg
    31321 agcgctggcg gatgctggcc tcgttcctcc cgtacttcag caccatccgc aagtcgatca
    31381 ccgtgctgat gaccgactac gcgcagcggt tccgggagcc gctgctgcgc gaggcgttca
    31441 acttcatcct ctacgagaag cacccggcct tcccggtgct gccgttctac ttccagctcg
    31501 cctcgcacgc caaccgggcg gccggggtgc ccgaaggggg ctcgctcgcc ctggcccggt
    31561 cgatcgagga gcgctaccgc aggctcggcg gtgagatcac ctacaacgcc aaggccgagg
    31621 agatcctggt cgagaacgac cgggcggtgg gcgtgcggct cagcgacggc cgggagtacc
    31681 gcgccgacat cgtggtctcc gccgccgacg gccacaccac ggtgatgaag ctgctcaagg
    31741 gccgctacct gaacgacacc taccgcaggc tgtacacctc gctgatcgac gagccgggcc
    31801 agctgtcgcc cgggtacgtc tccctcttcc tgggcctgcg ccggcccttc ccggaggggg
    31861 acccgtgcac cacctacctg ctgggcgagc gggagacgga cgggctgacc ggcatccgct
    31921 gccccagcat gaacgtgcag ttccgcaccc ggcactaccc ggagctcgcg ccccgggagt
    31981 ccaccgtggt gttcgccacc tacttctccg acatcggccc ctggcgggag ctgcgcgagg
    32041 gccccgagca gtcctcccgg gtgcggcgcg gcgaggaact gcacaccctg ccggtcaagc
    32101 acggccggga gtacaccgcg gccaagcgga aggtccgggg caccatcgtc tccttcctgg
    32161 acgagcgttt ccccggcttc aaggacgcgg tggccgtggc ggacgtctcc accccgctca
    32221 cccaggtccg ctacaccggc gtctacgacg gcaccttccc gggctggaac ccgttcgtgg
    32281 agggcagcga gaccgtcgag caggagatca agaagaacgg cccggtgctg cccgggctgg
    32341 agaacttcta cctctcaggg gtctgggcca ccatcggcgg cctgatccgg gcggccgccg
    32401 caggccggca cgtcatgcag ttcatctgcc gggacgacgg cgtggagttc cacgcggaga
    32461 tcgacccgag cgcgccgccg cccacccacc tgatcctccc ggtcggccgg ccgccgcagc
    32521 aggccggccc ggtcggggag atcccgtcca ccagcaccgc accgacaggg gccctggcat
    32581 gaagatcgag aaatgggtgg tccgcgagca cctcgacggg gtgccggacg tcaaccgggt
    32641 ctaccggaag gtggtcgagg acgtcacggt cggcctgcga ccggacgaga tgctcttccg
    32701 gaccaggtac gtctcggtcg acccgtacca gaacggcctc gcgctggaga cgccgatcgg
    32761 ccaccacatg ggcggcgact cggtcatgga ggtcctggag gccgggcccg aggccgcctt
    32821 ccgggtcggc gacctcgtcc agggcttcgg cggctggcgc agccacgtcg tccacaacgg
    32881 cgccgaggag gtgtggaaga ccggtacctt cccgatggtc ttcccggcct accggcggct
    32941 cgacccggcc tggtacgacg agaagctgcc gctctccacg gcgctcggca tcatgggcgc
    33001 cccggggatg acggcctggg gcacgctgac caggttcatg accgtccgcc ccggcgacac
    33061 cgtggtgatc agcggtgcct ccggctcggt cggcaccctg gtgggccagc tggccaggcg
    33121 tgcgggcgcc ggccgggtgg tcggcaccac cgcctcaccc ggcaaggccg agtacctcaa
    33181 ggagctcggc ttcgacgagg tggtgctgta cgaccaggcg gacgacgccg ggaaggcccg
    33241 cgaggcgctg ctgcacgccg cccccgacgg cgtcgaccgc tacttcgaca acctgggcgg
    33301 gacggtcacc gacgcggtgt tcaccatgct caacgtgaac agccaggtcg ccgtctgctg
    33361 gcagtgggcg acgacggtga acggcgagct gaccgggccc aggctgctgc cgtacatcat
    33421 gttcccgcgc accacgatcc gcgggatctt cgcccaggag tggttcaacg agccggagct
    33481 ggccgagatg caccaggacc tcggcgcact ggtccgcagc ggcgagatcc gctaccacca
    33541 gaccgtgcac aagggcttcg acgcgatccc gcaggcctac cgcagcctct acgtggaccg
    33601 ggaggcgaac cggggcaagg tgctggtcga ggtctgaacc cggaaacgaa acgtgggagg
    33661 ggcccgcagg cccctcccac cttcacgtac ccggccggac cgccccgcag ggctactcgt
    33721 cgtcgaggtc caggccgccg gcgtcgctgc cgtccggggt accgctgatc gcgtacccct
    33781 ggcggcgcgc ctcgtagcag gccaccgtcg cggcggccga gacgttcagc gagccgaccc
    33841 ggccgagctg cggcacgaag accacctggt cgcagagggc cagcgcgtcg ggggtgatcc
    33901 cgcggtcctc gtggcccagc acgaaggcga ccgccggggt cagctcggcg gcgaacatcg
    33961 gcaccgcctc gtcggccagc tccaggccga ccaccttgta gccgtccgcc ttcgcggagg
    34021 ccaccgcctc ggcgacggtg gggaagtgct ccaccttgag gtacttgtcg gtgcccatcg
    34081 cggccttctg cgcaccggac gagcgcaccg acggggtgtc gccggtcagg tacagcttct
    34141 cggcgcccat cgcggcggcg gtccggacca ccgagccgac gttgaacggc gactggaggt
    34201 tctccaggat cagcgcgagc cggaactcgt tgctgcgccg ccactggcgg tgcagccgct
    34261 tcagttcggt cccgcggagc tgcttcacga cgtcgtacct cgtccactct cggggcccgc
    34321 accctcgggg cggggccgcg cttccagaat ccggaacccg ttgaccgagg tgacccggct
    34381 ggtcgggtag ccctggtcgt tcagccactt ctgcagcgag tccgagccca ggttcttctg
    34441 caccaccagg aaggccgagc cgtccggggt gagccggccg agccactggt gcagcagccg
    34501 gcgcagggcg gccttgccga cccggatcgg cgggttggag tagatcgccg cgaaccgcag
    34561 gtcctcgggg acgtcctccg gaagggccgc ctgcacgttg cccagcccga gcgactccgc
    34621 gttcagccgg accagctcca gcgcgcgggt gttcacgtcg acgccccaga ccgggagccg
    34681 cttgcgccgg ctcgcccagg tcagggtgat cgggccgtag ccgcagccga cgtccaggat
    34741 cgggccgcgg acccgcggcg gcggggcgtg ctccagcagg acccgggtgc ccgggtccag
    34801 ccggctgcgg gagaagaccc cggcgtcggt ggtcagttcc agggtgaggt ccggcagggt
    34861 caccgtgatc ggacggcgct cgctggcgac ctcgggtgca ccggtgaagt agtgcgagcc
    34921 ggacatcatt tccccgtcgt tcgtaagggc ttcggggcca ccgggtgggt gtgggtaagc
    34981 cctgctggta cggcactgat ggtacccctg gcggcccggg ccccggatcc cgtgccgccg
    35041 gggaccggcc gggccgccgg accccggcaa cacgccggga ggcgggcggc gcatcgcgtc
    35101 cgggcggcag ccgacggata cttccagtac ccggggcggg accgtgggag cctccgagca
    35161 gcgaggacgg atgccatgcc gcagaatcac gaggactacc tggacgaggt ctccgagacg
    35221 gtggagccgg acgacgcggc cgaggagggc gacgagtacg acgagctggc cgagcgccgc
    35281 gccctcggcg ccgacccggc caccgaggtc gccgacgtcg cggagcagag ccggatcgtc
    35341 cagctcgacg aggacgagta ccgggagtag cggcccgctg cgctcgtccg ggccgtgccc
    35401 ggtttcgccc ggacccgccg cgcccggacc cgccgcgccc ggacccgccg cgcccggacc
    35461 aggctcagag ggcgccgcgc cgctggagcc aggtgaacgc cgcccagccc ggcagcaccg
    35521 ggaggaccag ggtcagcagg cggaagagcg cgacggaggc cagcgcaccg ccctcctcca
    35581 tcgacgcggt gtgctccatc agtgtcacca gcgcgctgtc cacggcgccg gccccgcccg
    35641 gggtcggcgc cgcgttgccg accgcgttgc cgatcaggaa gaccaccgcc accgaggcga
    35701 aggccggctc ccgcccgacc gcccgggcgc agcagtacag gcacgccacc aggcagagcg
    35761 agaccagcag ctggccggcg atgcccacgg ccagccgctg cgggctgcgc agcagctcca
    35821 gcagccgggg cagcacctcg gaggtcagcg gccgcagccg ggcggtcagc cagcgccggg
    35881 ccggcggcac ggccgagacc ccggctagca gtaccgcggc cccggccagg ccgcccacga
    35941 cggccggcag ggcgtccagc tcggagccgc cgggttccag tcccagcagg tagacgaagg
    36001 cgcccagctg caacaggtgc agcaccaggc tgaacagctg gccgacgccg acgctggaca
    36061 gcgcctgggc ggtcgggagg ccggcccgct ggaggaagcg ggtgttcagg gccaccccgc
    36121 cgacgccgcc gggcgagacc agcttcacga aggcgccggc gacctgggcg aggacggcgt
    36181 ggcggaagtc gagccgctcg gggacgaagc cgacgaagcc catcgcggcc gtgaagtggc
    36241 tggcggtcgc ggcgagcagg gcgagcacca gccagagcgg gtcggcgtcg gcgatggtgg
    36301 cgaccgggtt ctgctcgctc gcgaacagct ggggcagcag cagccacccg gccgccacgc
    36361 cgccgcagac ggccatcagg gtgcgggggc gcagccgctc cagcttgacc gcccgcaccg
    36421 gcgcctgcgg ccgggtccgg aggacctcgg cgcggatggc gtcgagcagt tcgacgggcg
    36481 gcggcggggg agcggcggcc cgggccgcct tggctttgga cgaggccttg gccagcgccc
    36541 cggcaggcgt cccggccggg ggcgcggccg gggtcgcggc ggcccgctgg gcggccgcgg
    36601 cgcgcctgag ggcggtgcgg gtggtacggg cgagggcgat gggctggagc agcgggaggg
    36661 ccgcgccgac ggcgtccggc ccgaggacgg tcaccgcgct gcgtaccgcc cgttcggcgc
    36721 cggtgcgcag cgcgagggtg gtgagcagct gggcgatgtc gcactgcagg accagttcgc
    36781 tcgccgcgat gtcgccgtcc gcgaggtcga ccaggtgcac cgcgccggcc tcgtccacca
    36841 gcagggcgga ggggaccagc gcgcggtgcg agatctcccg gcgctggagc agcgagagtt
    36901 gggtccaggc gtcggtgagg agcgcgtcgg tcagttcgtc gtcggccagc tggtccaggg
    36961 tgcggccggg caggcgctcg taggcgacca gggcggtgtc gcggccgagc tcgacggtgg
    37021 cggcgatccg gcgggtgcgg acgccggcgg cgacggccgc gtacgagacc agggcctcgt
    37081 gttccagccc ggtgcgcagg gagcgcaggg cccgggggtg cggcgcggtg cgcagtcgca
    37141 gccggcgcca ggcgcgctgg accagcgcgg cggtgaccgc ctgccggtcg agcagctgca
    37201 cgtcgaggtc ggggcggtcg gcctcctggc ggaccaggta gcggtcgggg ccgtccgggg
    37261 cggcggcgac cgggcgcagg cccgcctcgc gcaggctgtg caggagcagg gccggccggg
    37321 gccgcgggtc gggggtgccg acggcgtagc gggtgccgtg ggcggcggtc cagccgatca
    37381 gcaggccgag cagcagcgcg gtcggggtgg cgtacccggc ggcgagtccg gcgaggccgg
    37441 agacggtgag gacgatccgg ggcatccggc gttcgcgggc gccggaggcg gtgaggaagg
    37501 cgaggacggg ggcgaggtag ccgtagacgg gttcggtgtg ggcggggccg ccgccgggca
    37561 gccgctgggt gagtgcgtgg agcagcgagg cgggggcggc gccgtcgacc cagaggtcga
    37621 gggcgagcga gagcccgtag gcgacgacgg cggcgagcag cccgtcggag aggtgctgga
    37681 gggtgcgccg gcggtcgggt gcggacccga gcagccggcg ggccgccgag tacgccggga
    37741 cgagcagcag ggccgcggtg gagagtccgc cggcgatgcc ggccagcggg cgcgggacca
    37801 gccgggcggc cgcggcgacg tcggcggcga ttccgccgat ggtggcgcgg gcgtagtcgg
    37861 cgagcagcag gcagagggcg atcgcggcca ggccggcgag gcaccggatc agcgcgaccg
    37921 gctggcggat ccggccggtg ccggccgcgc cgcgggcgtc cgcggtgcct tcggtgcctt
    37981 cagtgccgcg ggggtccctg gcgtccgcgg tgccctcggc gtgttcgggg gccgcggtgt
    38041 cctcggtgcc ggaggcttcg gccggagccg ggatgtccgg tatgtccggc gatatgccag
    38101 ggtcggtctg cccggatata ccgcccgccc gggcaccgcc ggtgtcgctg tctgttctcc
    38161 ccgttacaac cgccacggtt ggcatgctcc catggcgccc gcccggcccg ccggggaacc
    38221 gggcgggcgc gcccgcccgg cgtcaggcct gccgggtcgg cagggcgacc aggtggcgca
    38281 ggttgacgtg ccgcgggcgg gtgacggtgt agccgatcag gtcggcgatg tcgtcggcgg
    38341 tcagcgcggg gatcgcggcg aacatcccgc cgagctgctc gcgcagcacc gggttgtcga
    38401 tgtgcccgcc cagctcggtg tcggtcagcc cgggctcgat cgcgctgacc cggacgtcgc
    38461 gcgggcccag ctcggtgcgg agcgcggcgg agagctgggt gagcgcggcc ttggtggcgc
    38521 cgtagacggc gtagtcgggg aagaccacgt gcgaggcgat cgaggagacg ttgaccaggt
    38581 cggcggtgcg gccctcggcg gcggccgcgg tgaggtcggg gctgaaggcg cggacgatcc
    38641 gcagcgcgcc ggtgaggttg gtgtcgatca tccgggtcca ctcgtcgacc cggccgtcgg
    38701 cgagggggtt gggcagcatc acgcccgcgt tgttgaccac gaggtcgacc ggaccgtacg
    38761 cgtcgtggac ggccttggcc gcggcgtcca ccgaggcctg gtcggtgatg tcggcggtga
    38821 cggcgagcgc ccggccgccg gcggcggtga tctcggcggc cagcgcgtcc agccgcccgg
    38881 tgcggcgggc cagcagggcg acgcgggcgc cgccggcagc gagcaggcgg gcggtggcct
    38941 cgcccatgcc gctggcggct ccggtgacga cggcggtgcg ggtggcgagg gcggggtagc
    39001 tcatcgggtg ctcctgaggg gtccgggcgg ggctgacggg gctgacaggg acaaccctgc
    39061 gcgcccggcg gccggctacc cagggctgcg cccttcctgg gaaagcggag cctgggaaag
    39121 cggagcctgg gaaaaccggt accaccttgg cgccgccgct cccggtctac gctgccgggc
    39181 atggagaaca ccgtggggga cttcctgcga tcgcgccgcg cccgcatccg gcccgaggag
    39241 gtgggcctgc cctcgcacgg ccgccgccgg gtgcaggggc tgcgccgcga ggaggtggcc
    39301 cagctcgccg gggtcagcgt ggactactac atccgccttg agcagggccg cggcggcagt
    39361 gcctcggacg cggtgctgga cgcggtggcg cgggtgctgg ggctggacga cgtggaggcc
    39421 gcgcacctgc gctcgctgac ccgcccgtcc aggacggccg ccgtgccgcg cggccggcag
    39481 caggtgcggg agggcacccg gctgctgctg gacctgatgc ccggcgtgcc ggccttcgtg
    39541 ctcggccgcc ggatggacgt gctcgcctgg aacgccctcg gcgacgcggt gcacggtttc
    39601 tccgcgcgcc cctccggcga ggccaacgcg gcccggcacg ccttcctcga cccggccgcc
    39661 cgggagttct acccgcagtg ggaggcggtg gccgccgaga ccgtcgccta tctgcggctg
    39721 gacgccggcc ggcacccgga cgacgcccgg ctcgccgcgc tggtcggcga actgtcggtg
    39781 cgcagcgagg agttccggcg cctgtgggcg gaccaccagg tgaggcagaa gacccacggg
    39841 gtcaagctga tccgccaccc gctggtcggc gaactcgact tcggttacga gacgctggcc
    39901 gtcaacggct ccgccgacca gctgctcgtc gtcttcaccg cccggccggg ctcgcccacc
    39961 gcgcagaagc tggccctgct ggcgagctgg acggccgagg gtgctccggc cgagagtgct
    40021 ccggccgagg gcgctccgga gcgggaagcc ccggccgccg cggactgacc cgggggcatg
    40081 tccgacctgc ggggcgtgtc ttggcaggtg ggcccgggcg gccgtcacta ccctgcgtgc
    40141 atgagcgcct gcgaagacct caccgcggca cccctggaca tcgagcccct cccgccgacg
    40201 gacggctgcg ccgactgcgt ggcccagggg cgccgggact gggtgcacct gcgggtctgc
    40261 ctggactgcg gccacatcgg ctgctgcgac ttctcgccgc agcggcacgc caccgcgcac
    40321 ttccacaaca gttcccaccc ggtgatccgc tcgtacgagc cgggggagga ctggcgctgg
    40381 tgctacgtcc acgaggtcat gggctgagcg gcgttgcggg ccgcgttctg cggtgcagga
    40441 acgggcgagg tggcagggcg ggcgaggtgt agggcggcta aaatccggac ataacgcccg
    40501 tgcggccctc ccggccgacg cctgtgcggc cggtgaccgc cgaagggagg ccgacgatga
    40561 ccaagttgat gccgagcagc acggccaagc tccgccgggg cacccaggag ctgctggagc
    40621 gccggggcat ggcgatgaac cccgggccga tgccaccacg cctgcgcacc aacgccccac
    40681 ccgcgggcgg cgccgcggcc ggcggcgtca ccttccggca cggcggccgc gacgccgacg
    40741 tggcggccat gcactccgcc ccggcgatgc acgccgaact gaagggccac cggcaccgcg
    40801 gcgcggagaa gcactccgcg cactgaacca ctccgcgcac cgaaccactg cgcgccggag
    40861 cactccgcgc accgggcggg acgcggccgt cgggggcggg gagccgagca cgggctcccc
    40921 gcccccgacg gctgcccggg tggcggcccc gggatctctc ggggtcggct ccgggccgcc
    40981 tggggggccg tcccggatgg ccgccgcgtc gtactccaac agactcgttc ccggaaagag
    41041 cacgagccgc cggacgagcc acagttggag accagcccga tgaacaccac tcagcgccac
    41101 cgtcgttgga ccaccctcgc cgtctccggc gccttgctgg ccggcgtcgc cgccggtgcc
    41161 gcgacaccgg ccctggccgc cgaccggacg gcgggcagcg cgagttcggc cgacgccgcc
    41221 gcccgcccgg ccggtccgct cgaccgcgag gcgatggcga agacgctggc cggtctgccg
    41281 gacgacggca tcaccggcgc gctggtccgg gtcgacggca ggggcggccg gtgggccggt
    41341 acggcgggtg acgtcccggc ggacgcccgg ttccggatcg gcagcatctc caaggtcttc
    41401 accgccaccg tggtgctcca gctcgccgcc gagcggaagc tcgacctgga cggcagcgtc
    41461 cagcagtacc tgcccgggct cctcccggcg tcctacccgc cggtcaccgt cggccagttg
    41521 ctcgaccaca ccagtggtct gccgggcggc ggcggtctca cctccgggga cggcaccgag
    41581 agttggttcg ccgcgcacaa ggccgactcc tggacgcccg cccaggtggt cgcggacgcc
    41641 gtcaagcagc cgatgggctt cgcgccgggc accgcgcagc agtacaacgg catcaacacg
    41701 ttcgtcgccg ggatggtggt cgagaaggtc accggccata ccttcgcccg ggaggtacag
    41761 acccggatcg cccgcccgct cggcctgcgt gacaccgtcg tcccggaccg cgacgacctc
    41821 accctgaccg gtccgcacgc gaaggtctcc gtggacgtcg gcggccaggc gggcccccgg
    41881 cagctggtgg acgtcaccga gcagagtccc tggccgtggg cggagggcgg catgatctcc
    41941 tccgccgccg acctggaccg gttcatgacc gcgctgttcc gcggccggct gctgccgccc
    42001 gcccagcagg ccgaactgtt cgacgtcccg gacgtgccca accaccgcaa caagaactgc
    42061 gagatcggcc cgaccgccgg tcacgcctgc ttctccaagg gcctgatgag cgccaccctg
    42121 cccaacggcg tcgtggtctg gggcaagacc ggctcccgcc ccggctacac cagcggtgtc
    42181 ttcgccacca aggacctcag ccgcaaggtg gtctactcga tcaacccgac cggcatctcc
    42241 ggcgccgagt tcccccggat gtggcagatc gtgaccacct ccttcggctc cggccagaag
    42301 tacggcgacc agccggagta gggccgctga tgtcggtggg ctgcggtacg ttcgtgccga
    42361 tcactggtgg gtgcggcgga catgggggcg tgcgatggcc gacctgatga cggaggagcc
    42421 ggtcgagctc cagctggagc ggtaccggac ggagctgacg ggctactgct accgcatgct
    42481 cggctcggtc ttcgaggccg aggacgcggt gcaggagacg atgatccgcg cctggcgcgg
    42541 ccaccggggc ttcgagggcc gggccgcgct gcggtcctgg ctgtaccgga tcgccaccaa
    42601 cgtctgcctg gacgcgctga acggccgcaa cggccgggcc cggccgatgg acctggccgg
    42661 gccgtccacc gtggccaccg cgaccgacgc ccgactgccc gaggtgacgt ggatcggccc
    42721 ggcgccggac ggccgggtgg tgtccgagac gggggacccg gccgaggtgg ccgcccagcg
    42781 cgagtcggtg cggctggcgt tcgtcgccgc gctccagcgg ctggcgcccc ggcagcgggc
    42841 ggtgctgatc ctgcgtgagg tgctgggctg gaaggcggcc gaggtcgccg aactgctggg
    42901 cgtcaccgtg gcgtccgtga acagcgcgct ccagcgggcg cggtcggtgc tctccacgga
    42961 cgccgcggcg gtccgcccgg cgtccgcgct ggacgaggac caccaggcac tgctctcccg
    43021 ctacgtctcg gccttcgagg cgtacgacat ggacgggctg gcggcgctgc tgcacgagga
    43081 cgtcacgctc aacatgccgc cgttcgagct gtggctgacc gggcacgccg acatccgcga
    43141 gtggatgctc ggcccgggcc acggctgccg gggctcgcgg ctggtcccgg tggaggccaa
    43201 cggcagcccg gccttcgggc agtaccggcc gagcccggcg ggcggccacg agccgtgggc
    43261 gctgatcgtg ctggaggtgt cagagggccg gatcaccggg ctcaccaact tcctcgacac
    43321 cgacgtgctc ttcccgctct tcggccttcc gccgaggctg gacgccgagt aggtccggca
    43381 ggccgtcctg cgccaccggc ggcaggacac cggccagccc gctgaacgcg agcagctccc
    43441 gcagggggcc gctcacgttc ttcagttcca cccggacgcc gtgccgggcg gcggcgagcc
    43501 gcagccgggc gagggcgtcc acgacggcca ggtcggcgcc gggaagtgcg gcgaggtcgc
    43561 aggtcagccg ttggtcctgc gacagggtca ggggtgtctc caggttggtg ttcacggagg
    43621 ttggaccgga gcgtcgggtg tggctcatcg gtccgtcgga agaattcggc ggagagccgt
    43681 ccgagcagct cgccgtgtcg aagaggaccc ccgggcgggt gtgccgcgta cggtgccggc
    43741 ccgtgccggc cggcaccggc acctactgca ccggaccgcg ccgcgccgtg ctccggcatg
    43801 ggtggcagag tgggcggcag ttgcccctgc gccggaggag gaccgcccgt gtcggcagag
    43861 ccgtcgaagc ccgagccgtc gaagcccgag tcgttgaagt ccgagccgtt gaagtccgag
    43921 ccgtcggggc ccgagccgtt gaagtccagg gaggagtggc tggcgtccct gccgcgggtc
    43981 tacgcggccg ccgggtgcgt gctgcgggac gcgtcgggcc ggatcctgat cgtgaaggcc
    44041 ggctaccggg agcactggca gttcccgggc ggcacgatcg acctcgggga ggggcccgcc
    44101 gagtgcgccg cgcgggagct gaccgaggag accgggctgg tccggccggc cggcgacctg
    44161 ctggcggtct cctggaccca cccctccgcc gaactcgacc acccggccgg gcacttcctc
    44221 ttcgacttcg gcaccgtccc ggacggcacc cccgtgaccg tcccggccgg tgagctggac
    44281 gactaccgct gggccggcga cgaggaggcg ctcgaactcc tcggtccggc aaggtccctg
    44341 cggctgcggg cggcgatgga ggcggccgcc gacgggcggg ttcggatcgt caccacccac
    44401 gtgtccggct tctgacgccg cccgggcccc cggggtgccg ggggcccggg tgatgcgctc
    44461 attcctgcgt gtcggcgcgt gccgcgatgt acgccgcgac ggcctccgcg gtgaaggtct
    44521 ccgcctcggc cttgtccacg ccgaggtcgg tgagcgggcc cgcaccgttc gcctgctcca
    44581 gcagtgcgag caggatgtgt tcggtgccga cgtagttgtg cccgagcttg agcgcctcgc
    44641 ggaaggtcag ctccagcacc ttcttgccct cggcgtcgta cgggatcagc ccgggcgtct
    44701 cgtcggccgc ggcgggcagc gtggcggtga ccgcctcccg gacggcctcc ggggtgatgc
    44761 cctgggcggc cagggccttg acggccaggc cctccggttc ggcgagcagg ccgagcagga
    44821 tgtgcccggt gccgatctcg gcgttgccgg cccgtcgggc ctcctcctgc gactccatca
    44881 ccacgtgccg tgcccggggg gtgaagcggc tgaagccctg gctggggtcg aggtcggcgg
    44941 gcgtgcccgg gtccttgggg acgaaccgct tctgggcggc ctgcttgctg acgcccatgc
    45001 tgcggccgat gtcggtccag gacgcgccgg aacggcgggc ctggtcgacg aagtggccga
    45061 tcaggtggtc ggcgagctcg ccgaggtggt cggcggcgat gaccgcgtcg gagagctggt
    45121 cgagcgcgtc gctgtggacc ttcttgatcg cgtcgatcag gtcgtcgagg cgcagcggag
    45181 tggtcttggg aacaacggga ttctccatgc gtcaaccgta ggttgtcgac ccgaggatcg
    45241 tcaaccatcg gttgacgatg ttccgagttg tggcgatcgg ttgtccgggc gcccggcggg
    45301 cctgtcgttc agatggtcag cttgaacccg tcgtgactgc gcgcgaagcc gagcgaggcg
    45361 tagaagcggt gagcctcggt gcggcgcttg ttgctggtca gctggaccag cgtgcagccg
    45421 cggtcacggg cccgcccgac ggcccgggtc agcagctcgc gcccgaggcc ggcgccccgg
    45481 cggtcggcgc gcacccggac ggcctcgatc agcgcgcgct cctcgccgtg ccggccgagc
    45541 ccggggatgt aggtgagctg gaggcagccg agcaccgtgc cgtcgccctc gtccaggacc
    45601 atcagctcgt tgcgggagtc cgcgtccacg tcggcgaagg cgcgggcgta ggcttcgtcg
    45661 acccgtacgg tggcggggtc ggtcacccgg tcctcgtcgg cgagcagggc gatgacggcg
    45721 ggcaggtcct ggcgggtggc ggtacggaag atcacgcccg gagtctgcca gaggcggtcc
    45781 ggcaggggtg gtccggcagg ggtgccggcg gggttgcgag gagggacgtg cggatactca
    45841 ccgcgccgga ggccgaggtg cccggcgaac tcaagctcca ggtggccgcg ttgcaggacc
    45901 aggcctggcc cggcccgccg gtgccgtcca ccgcgctggt gcacgacccg gcgctgcggc
    45961 cggtgtcgat gctgctgctg gacggcgacc gtgtggtggc cgcgctcgac gtgctctcca
    46021 aggaactgga ccacgccggg cggacgttcg cggcgagcgg gctgagcgcc gtggtcaccg
    46081 accgggcgcg gcgtggccgc gggtacgggc ggaggctggt ggcggccgcc cgcgccgccg
    46141 tcgtgcaggg cggcgcggac ctcggcctgt tcacctgcga ccgcggcctc cgcggcttct
    46201 acgagggtgc gggctgggag ctgctgccgg gcgcggtgct ggtcgggggg acggccgagg
    46261 agccgttccc cagtgatcag gacggcttcg acaaggtcac catggccggc ttcttcaccg
    46321 accgtgccgc ccggcaccgg ccggacttcg agggccgacg gatagcgctg cacccgggtg
    46381 acatcgaccg gctctggtga tcggcgcgcg gcccgtgatc ggcgtgcggc ccgtgatcgg
    46441 cgtgcggccc gtgatcggcg cgcggcccgt ggcccgtggc cggcggttcg tccggcgatc
    46501 ggcggtgcgt ccggcgaccg gccgcgtacc gggcggtccg ctacgcgccg ggtggcccgc
    46561 tacgcgtcca gcagccgggc gcggacggcg gcgaggtcgg ccgggtcgac accggcggcg
    46621 agcaggtagc cggccgggtc gaagccgtcg agcgtggcgt acagggcggc ctcggcggtg
    46681 gtgccggcct cggagagcac cgcgtcgatc cgcaggtgct ggtcgggcag gccgagcatc
    46741 ccgtacagcg ggcggacgtt gggggcactg agcaggtagt cggcgacgat ctcggacggc
    46801 tcggcacccg cgagggcgag cagcagcagg gcggcgaggc cggtgcggtc acggccggcg
    46861 ccgcagtgca cgaccagtcc gccgggccgg gcgccggcga tcgtggtgac cagttcggcg
    46921 gcggcgtgcg cgcagtggtc caggtagggg cggagggcga gcggggtgcc gtccagcctt
    46981 ccgtacgtct cccaccaggc ggggccggcc agttcgtcca gcgggacgcg gatcagctcg
    47041 acgccctcgg ggagggggag gaggggcttg tactcctcga tgttgcgcag gtcgacgacg
    47101 gtgcgtatgc cgtggtcgag gagggtgtcc cagccctcgg cggtgaggcg gtccaggttg
    47161 tcggcccgga cgatcgcgcg gtgggcggtc cggccgccgt cggtggtgcg gattccgccg
    47221 aggtcgcgga cgttgaggca gccgtcccag accagcgtgc ggtcgtcggt ggtggtcagc
    47281 gcgtgcgtcc ggctcatcag gtccccgtct ctcaccgggg gtccgttacc ccctcgttat
    47341 cagaggacta tcggggcggt cggatggttc ctcggttgtg tgacctggcg tcagcagcgc
    47401 tccggccggc gatcagcaga cggtcggctc ggcggcctcg gcgcgcacca gcttctccat
    47461 cggctcggcg gcggtctgac cgagcaccga gccgacgacg atcgcgccca ccaggaggac
    47521 ggtggagagc caggccatcg tcgacaccgg gagggtgaag gcgccgacca cgcgggccgt
    47581 gcactcggcc agcagggcga cgccccagat ccccgagagg aggcgctcgt agcggcggaa
    47641 cgaggcggag cgggccgccc ggccctcggc cagccgctgc caggcggcgg aacgggcccg
    47701 gtcgcccctg gtcaggaagg gcatcaccat cggcgacatc agcggccggc cgatcagcgc
    47761 ggagacgagg atcgccagcg cgaggctgcc gctgagcgcg ccgtccttgg cgagcatcag
    47821 ccgggcgtcg ccggtgacgg tggtgagtgc caggccgacg acgttgacgc cgagcatcat
    47881 cgacgcccac aggttgagcc tgcgctcgcg gagcaggccg gcgacggtcc ggacggccgg
    47941 gatcgcgccg ctccaggcga gggcggcgaa ctcgctcatg ccgaacgcgg agtgcagcag
    48001 gtagtagccg gccagtgggg cggcgacgtc cagggcgagc gggcggaggc cggcggcgag
    48061 cgggttccgg gccttggcgg tggccgtgtc gtccgtggcc gtgccgtcgg tgctcttggc
    48121 gacggcgacg gcgacggcga cggtggcggt gacggtggcg ggggcgctga gggtctggct
    48181 cacggtgggt tcctccccgg actggctgct cggcctgcgg gccgttgccc gcgtcgtgcc
    48241 tccatttttc cgggccgacc ctccgtcaga gcagtgtcgt ccgtggcggg atccgcatga
    48301 cagttgtcac agtgcgcgcc atgacgggcc cgccgacctg caccttcacc cgtcggcccg
    48361 cgccttcatt cgtcgggtcc gcgtctacac ccgccgtccc gcgtcttcac ccgccggccg
    48421 gggtgtgacc agccggtgcg ggctgggcgg cacctccccc cccggacgtc ctcgccgacg
    48481 ggcagcgcct cccgccggct tccggggacg actcccgccc gctccccgga accggcccgc
    48541 ctcgctcccc gggacggtgc cgcccgggcc gccgggcccc gcgccgggcc tcccgcgacc
    48601 cgggcgacgc gtaaccgctc gcccggatgg cgcatgatgt ggcgggtgca gagtgcagag
    48661 cgccccggag cgggcaccga cagccccgtc ggccggcccg gaccgccacc gacgtcgggc
    48721 cccccggccg gtcccccgtc cgtcccaccc ccgggggccg cccccgccga cctgtcggcc
    48781 gcggtccggg ccgcgcagga cggggacgag gaggcgttcc ggctgctgtt ccggagtgtg
    48841 cagccgggcc tgctccgcta cctccgggtg ctggtcggcg gccgccccga ggacgcccag
    48901 gacgccgagg acatcgcctc cgaggcctgg ctgcagatcg cccgcgacct gcgcaccttc
    48961 tccggggacg gggacggctt ccgcggctgg gcggccacca tcgcccgtaa ccgcgcgctc
    49021 gaccacctgc gggcccgccg ccgccgcccg gtcgccgacc tgccgttcga gtacctgtcc
    49081 gagctggccg ccggggacga cacggccggc gcggcgctgg cctccgtcgg tacggcggac
    49141 gcgctggccc tgatctcccg gctgccccgc gaccaggccg aggcggtgct gctgcgggtg
    49201 gtgatggagc tggacgcgga gagcgccgcg cgggtgctcg gcaagaagtc gggcagcgtg
    49261 cggatggccg cgcaccgggg actgcgccga ctggccaagg tgctggagca gtccttcacg
    49321 gcgggtgcgg ggatcccggc ccagtcgctt gccgggccgt ccgggcagcc ggtccggcag
    49381 gcggctgggc gcggggcggg gccggtggcc gggcccgccg ccgggccggt cgagaggggc
    49441 gggaaaaaaa attctgcgca gggtgtgaca gaacgccggg ccgcgacgct gaaggacatg
    49501 a
//
