LOCUS       NZ_CP026498            25276 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. CB01881 chromosome.
ACCESSION   NZ_CP026498
VERSION     NZ_CP026498.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CB01881
  ORGANISM  Streptomyces sp. CB01881
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     A 3-hydroxy-3-methylglutaryl-CoA synthase gene based probe for the
            discovery of the acyltransferase-less polyketide synthases
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2018) Xiangya International Academy of
            Translational Medicine, Tongzipo, Changsha, Hunan 410000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002953255.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 02:39:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,978
            CDSs (total)                      :: 7,904
            Genes (coding)                    :: 7,565
            CDSs (with protein)               :: 7,565
            Genes (RNA)                       :: 74
            rRNAs                             :: 5 (5S)
            complete rRNAs                    :: 5 (5S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 339
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 339
            Pseudo Genes (frameshifted)       :: 124 of 339
            Pseudo Genes (incomplete)         :: 251 of 339
            Pseudo Genes (internal stop)      :: 10 of 339
            Pseudo Genes (multiple problems)  :: 45 of 339
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:44:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6395658
            Orig. end                         :: 6420934
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026498.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25276
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="21"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25276
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25276
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15276](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15276)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    38..52
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            complement(817..1650)
                     /locus_tag="C2142_RS17620"
                     /old_locus_tag="C2142_17625"
     CDS             complement(817..1650)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17625"
                     /product="hypothetical protein"
                     /protein_id="WP_148643529.1"
                     /transl_table=11
                     /translation="MARERWLVDGYELTDGLVRDVEYRSGLATTPVVVGANAAVPNRIG
                     ELWRPKHHGPGKFTLALWLAPRAGGWQAVEQAWEDLLRAIARPHRLLTFERYTAAGQLR
                     RCQGEVLSALAPTPLGQNGLRVGVEVNVPAGYWESGDIAFEATAPGSPLPQDLDLDPFA
                     DATAPMEQLAYRITGPITAPTVTDTSDGPGRNGDSFTYTGQIAAGQSLTVDSATWQLTG
                     TGGLVPDPARLTNTGPAFLRLAPGRPGIPPSVRLTGTNPGAGTQLTVTGRRAYLT"
     gene            complement(1650..5354)
                     /locus_tag="C2142_RS17625"
                     /old_locus_tag="C2142_17630"
     CDS             complement(1650..5354)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17630"
                     /product="hypothetical protein"
                     /protein_id="WP_148643530.1"
                     /transl_table=11
                     /translation="MTDEIDSGRLVVQVAADSSGFAQDARARVDAATRNLRARVRLEPD
                     TTGLRQRVQAAAQAARARIKVAVDADTSGLAEKIRAATARGAYVRVGVAFDTGNLRRRV
                     EVAVEAATNTVKVGLDVDTAGLRSRVRAALAGLSVNVRVEVDTTAAAARVAAFRTTAGR
                     ALDIPINTGGGGAGGGLAEAADGLGSTIAGLMRLPAMASGALALGQALTQAAGGLFAMG
                     AAAAPAVGLLGALPGAMSAAAQGAGTILAAFSGIGAAVKALGQADTQSAGASSAAAQAR
                     QAAADRVADAQRRLGAAQRDADEQSLRGAEQVAQARRRLADVQEQAAAAVAAADRQLAA
                     AELTVTRANQAATRAQEALNDARRDAQRSLEDLNRDAARGPLEEQKALLSLEQARSRLN
                     EVNTSPFASETDRREAQIAFQEATNQLEDVRVRNQRLAEDVKKANQEGVEGSDQVTAAK
                     QELTRAQEAEQDAVRGVQDAEQQAARSRVEAVREVQDAHTELDRTVRDAERQQKRSAEQ
                     IADAQRDVARALRDQTQALTAGGTAANAAAAALDKLSPAGQRFARFLQGTVQPALRGLR
                     DTAQEALLPPLETAITRGMQLLPIFNSALAQTGQVLGQVAIRGAEMVTSGPWRADLAQI
                     AATNTRVIASLATAGLSAADVLRNITVAAGPLLERLAGAAERGMAAAAAFVQAGRDGGQ
                     LGAFFQRAGDTGAQLWGILRDIAVGVFHIGQAAAPAGQALLTSLASAASSFRTLTGEGE
                     TQAKLAGYFANTVPVVQELGRLVAAVGVAWFNFTNNPALAPLIARLRTEFLPAVMQLAG
                     ALGNGQLWGQLLGLITSVANIAAELGGLGNTLSGFLLVMQGVASAVEVLLSIPGMGAFV
                     SALLTIAGVAAGLMAVSNAIAAVRVAMLALSANPLMLIITAIAALVVAFITAYERSEWF
                     RNVVNAAIGGLVSGVRIALQGLVDFVKWIWPTLTTVFGWPIKFWVNTVYDGGIRRLWNS
                     LADAFGLGKLPSFTVNFARGGVVPGYAPGRDTVPAMLSPGEGVLIPQAVRQLGGEGGIT
                     ALNDAARAGRLADAGAPVQGYFLGGIVDGAMDRLRGWAAGALAKALNPLRSWFNWMPDN
                     AWGDMMRGMVNRAVDGVLSFVRGYATGGVVPGYAPGQDSTLARLSPGEGVLTPQTVRGL
                     GGTSAVGALNAARGQLADGGQGDRIGTVISPGAIVQYITNPLPESPGETVNNRLRALAS
                     FGLFDKESA"
     gene            complement(5344..5613)
                     /locus_tag="C2142_RS17630"
                     /old_locus_tag="C2142_17635"
     CDS             complement(5344..5613)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17635"
                     /product="hypothetical protein"
                     /protein_id="WP_148643531.1"
                     /transl_table=11
                     /translation="MRGLPAEALLRRDAGEVGSDRWGLTQELLAQAVELISVMAAERRL
                     RQPVELPRPAHLRAGHTQGHDADGIARAVAVLRGTTRKAPRGDG"
     gene            complement(5619..6212)
                     /locus_tag="C2142_RS17635"
                     /old_locus_tag="C2142_17640"
     CDS             complement(5619..6212)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17640"
                     /product="hypothetical protein"
                     /protein_id="WP_148643532.1"
                     /transl_table=11
                     /translation="MPGIDLDAARTRRLAAAADKARAAKAEYTVGEEPIILGGAQVALL
                     PAELPLEVWQPLIGIPYLPLLLRKLVEAAQSKGEQQAEAAGLIVDVLGSEPGLPSDLIA
                     AAGEMGRRLLGEDGYTRLMAERPSHSDVLELVRYAWTKYMGGGAGLGELIGPSETPSNA
                     GTTSKPTSSASTTSTPGASGDGPVTLDSSAPAAS"
     gene            complement(6388..6753)
                     /locus_tag="C2142_RS17640"
                     /old_locus_tag="C2142_17645"
     CDS             complement(6388..6753)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17645"
                     /product="hypothetical protein"
                     /protein_id="WP_148643533.1"
                     /transl_table=11
                     /translation="MELPYPEGTFVRLDQEGEYTRFGTLVQLAPGWYGIQQRPGGRVEA
                     IASGSARIRPWARRRVRVFYTESCMCEWGPCGPGWRWSSETDGWAGRDEWRERLYTTQP
                     EALGAALEWLYAALRPV"
     gene            complement(6975..7526)
                     /locus_tag="C2142_RS17645"
                     /old_locus_tag="C2142_17650"
     CDS             complement(6975..7526)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17650"
                     /product="hypothetical protein"
                     /protein_id="WP_148643534.1"
                     /transl_table=11
                     /translation="MFVAQMARLYLAVPGTVAPADPIVAMPAAWKDVGLFKPGSLEWNT
                     DPKFEEIKSHQLRYAARTIQTEDAATAKVELQEWNATNIVAVYGGGAVTSVTAGGKTFY
                     RYTPPAVGGRNQFAAVIELIDGAKHYRRIVPLCEQVASVNQKFPNDAESTLPLELKVIG
                     GAVGDPWYDLTDDPGFAPTA"
     gene            complement(7686..8114)
                     /locus_tag="C2142_RS17650"
                     /old_locus_tag="C2142_17655"
     CDS             complement(7686..8114)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17655"
                     /product="hypothetical protein"
                     /protein_id="WP_148643535.1"
                     /transl_table=11
                     /translation="MRDLASLDAELLVVDWLSNHEELTGVLGGKGRIGARNAPPYPRIR
                     ITQIPGGAAAGWRWLGTFHIQVEALGDLDRSTARPALHLAFSTAVKALHELTVRPALPG
                     QPVVTAVQALSTGGWLPEPTGQGRYLGVVALTAHPAAG"
     gene            complement(8107..8352)
                     /locus_tag="C2142_RS17655"
                     /old_locus_tag="C2142_17660"
     CDS             complement(8107..8352)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17660"
                     /product="hypothetical protein"
                     /protein_id="WP_148643536.1"
                     /transl_table=11
                     /translation="MASNVRITLAHHLTRDGAALAPGDEIEVPHHEARQLIASGYVAGV
                     DPSDPEAVAKALAPEPSRKQLAAKPSADKAEAKPSA"
     gene            complement(8463..8933)
                     /locus_tag="C2142_RS17660"
                     /old_locus_tag="C2142_17665"
     CDS             complement(8463..8933)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17665"
                     /product="hypothetical protein"
                     /protein_id="WP_148643537.1"
                     /transl_table=11
                     /translation="MARLELPPDIADRLAPLLARRAERLAEEVAVEARRLAPGAKTWHT
                     REDGHARPSHRDADGQTRAAPVPFNVGGALLAGPRDPSGPIEETAGCRCTVTEDPEAVA
                     ASITAGKAAIRGSRAEAQVVCDFPGAADAEFAQGEGTHFMSRAAAQVATRHR"
     gene            complement(8933..9274)
                     /locus_tag="C2142_RS17665"
                     /old_locus_tag="C2142_17670"
     CDS             complement(8933..9274)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17670"
                     /product="hypothetical protein"
                     /protein_id="WP_148643538.1"
                     /transl_table=11
                     /translation="MAVLLAARQLGVRTRGMPVLDAYGDETTGPPGELRGPWPGRAQPH
                     TDGTWLLAVDPRAGLLLAGDIVAEPATGAEWTVLAADELRNAVDPALTYVRVTARPRVA
                     GGTRPEGHR"
     gene            complement(9274..9879)
                     /locus_tag="C2142_RS17670"
                     /old_locus_tag="C2142_17675"
     CDS             complement(9274..9879)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17675"
                     /product="hypothetical protein"
                     /protein_id="WP_148643539.1"
                     /transl_table=11
                     /translation="MELIVTPEDVARRLGYPTPLVDELRQRIETAIEDAQDALVAHLGR
                     PLLPAEYTETGVHAGPDGWILHHAPVVTVLSATSEPNSPPGPFGIGAPTYTVRYLAGID
                     ARSMPETAPLRLWLRATACHHPLLADAPARQRRISSASVEGQSVTYDTAAEPPALLAPP
                     DLATTDRWRLRGRRVYQAPVRPTPPGLTIRGIPGTGGL"
     gene            complement(10001..11002)
                     /locus_tag="C2142_RS17675"
                     /old_locus_tag="C2142_17680"
     CDS             complement(10001..11002)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="C2142_RS17675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_17680"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_148643540.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.8e-37, bitscore:
                     127.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDAPAPHQAEKAVLSALSGTPLPEAAALAGLSPNELTDALDLYR
                     AAGLNALTTQTTAAATGAWIQVYVQPADWDQAEQHLAAHLGPHLRQAENSGAVHAWWYV
                     RKHPCWRLRLQRGPAATADDFQKATARLLDRLREQDVITAWWPGIYEPEAAALGGPHGI
                     AAAHRLFHADSRAILVHTHWRNTDSPRPVIGRRELSMMLCSHMLRAAGQEWTEQGDVWD
                     RVTHMRPLPETATDDLDRLTASVGTLLSADTGALARPGARLEYAATWAYEFHTAGQALA
                     AAARTGDLTRGLRAVLAHMVIFHWNRAGIPTATQGALARAARNHVLGPLRDA"
     gene            complement(11018..12223)
                     /locus_tag="C2142_RS17680"
                     /old_locus_tag="C2142_17685"
     CDS             complement(11018..12223)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009319710.1"
                     /locus_tag="C2142_RS17680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_17685"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_148643541.1"
                     /sec_met_domain="LANC_like (E-value: 1.5e-41, bitscore:
                     141.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARTAHPHPTAPASRPVVPCGPDDIQHSQALATGAVGITLLHIE
                     RAEIGVGSWASVREWLVSIAASPLIASDDASLFVGAPALAFVLNTAAGTTGHHRDTLRT
                     LDAAVTKLTTRRLDQAHARIDRGEHTTASEYDLLYGLTGLGAYLLQRDPRSDTLHDVLA
                     YLVRLTQPLPGSDLPGWWVRHDPSGRTSGAFPGGHGNLGLAHGITGPLALLALAKSAGA
                     LVDGHADAMLRILAWLDGLRQDVPAGPWWPQWVTADEHRLTTVFQEGPRRPSWCYGTPG
                     LARAQQLAATALGDDRRKKAAEHALLRCITDPAQLAQIGEPGLCHGAAGLLHTVHRVAQ
                     DAARPDQFTAHLPALRALLHAQVPARQPGFLDGTAGTALALHATDRGGAPTTSWDACLL
                     LS"
     gene            complement(12223..15276)
                     /locus_tag="C2142_RS17685"
                     /old_locus_tag="C2142_17690"
     CDS             complement(12223..15276)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="C2142_RS17685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_17690"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_148643542.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.5e-190,
                     bitscore: 633.5, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 8.3e-20,
                     bitscore: 70.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.1e-27, bitscore:
                     96.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRAVDAVLLRATADSETAIGPWPDLSGDDPPDGAAWQRWLAEAW
                     ASPDAAGAVDLASPVLASRVRAACAGRITSDRQLRRLGESLVRYVLRMRHRATPFGLFA
                     GVAPARLGDSLEVSWAGRHRAAARPDAAWLAGVVNRLEAEGTLLRRLLVIADATCQVRG
                     DQLVLPCRQPPPGGDAPQEVSARRTPPVAAILAAARDAVPLEELVQKVGAEFPDAPPGA
                     IDRLVMQLVEQRMLITSLRPPMTASDPLGHVLAQLGHVGAADLGSVEPSVRLLTALHSR
                     LERHNGEDPARQGSSRLDALNIMAAVPSDVTPLLAVDLRLDCALVIPACVAKEAERAAD
                     ALALASPYPQGPPAWRDYHGRFLERYGPGAHVPLLDLVKPDTGLGYPAGYRGSPLPVEP
                     PAMQDRDATLLEVAQLAALDGLAVVDVTDVLPRLANGPVEQTPAHLELCFQLHSDSQAQ
                     LDDGLFTLVVTGLAQGAGTTTGRFLYLLDSADRRRMAGALRRAPALAAGAVRAQLSSPP
                     LRVRTENVARTPAVLTETITVAEHEQGTMALADLAVTADARRIWLVSRLTGRPVEPAVL
                     NAVQLSNFTHPLVRFLAELPRARAAVLAPFSWGPAAGKLPYLPAVRHGRSILAPARWRL
                     HGTDLPPAAASWRDWDNALASLRERRLMADTLDLGDGDQRLRLDLAERHHRQLLRAHLD
                     QHGRAILREAPVPSALGWIGGRAHELTIPLVSTQEPVRLPAPRHPAAPAPGRSPGAPGP
                     GWAYAKVYAHAARHTDLLARLPELTATFGESPWWFIRYQDPDPHLRLRIRHGDGGFAET
                     ARQVGIWVQNLADAGLATGRVQWDTYWPETGRYGEGQLLGLAEWVFVADSAAVLAQLQH
                     TGPGRLPAPALTAASMTDIAASFLGGTEAGMRWLIDNLARTPASAPDRTLLTQAVALAD
                     PADTWAALRAATGTGITEAWARRRAALDAYRRRLIVLDGPPADTVLTSLLHMHHIRAAG
                     IAPDAERACRRLARAAALSWTTRTHGAT"
     aSDomain        complement(14548..14820)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C2142_RS17685_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.90E-22"
                     /identifier="RREFam001.1"
                     /label="C2142_RS17685"
                     /locus_tag="C2142_RS17685"
                     /protein_end="243"
                     /protein_start="152"
                     /score="70.1"
                     /tool="antismash"
                     /translation="VIADATCQVRGDQLVLPCRQPPPGGDAPQEVSARRTPPVAAILAA
                     ARDAVPLEELVQKVGAEFPDAPPGAIDRLVMQLVEQRMLITSLRPP"
     gene            complement(15357..15503)
                     /locus_tag="C2142_RS17690"
                     /old_locus_tag="C2142_17695"
     CDS             complement(15357..15503)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04363.1"
                     /locus_tag="C2142_RS17690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_17695"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_148643543.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.9e-18, bitscore:
                     64.9, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNTQINDFELDVTLVEQGPVIAELMSSTDDGCGQTCASACSNST
                     CVA"
     CDS_motif       complement(15441..15503)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKNTQINDFELDVTLVEQGPV"
                     /locus_tag="C2142_RS17690_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15357..15440)
                     /prepeptide="core"
                     /locus_tag="C2142_RS17690_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-8.20"
                     /molecular_weight="2481.7"
                     /monoisotopic_mass="2480.0"
                     /core_sequence="IAELMSSTDDGCGQTCASACSNSTCVA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNTQINDFELDVTLVEQGPV"
                     /leader_location="[15440:15503](-)"
                     /alternative_weights="2499.7"
                     /alternative_weights="2517.7"
                     /alternative_weights="2535.8"
                     /alternative_weights="2553.8"
     misc_feature    15496..15510
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.24"
                     /tool="antismash"
     gene            complement(15572..16813)
                     /gene="fxlM"
                     /locus_tag="C2142_RS17695"
                     /old_locus_tag="C2142_17700"
     CDS             complement(15572..16813)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329291.1"
                     /locus_tag="C2142_RS17695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_17700"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_148643544.1"
                     /sec_met_domain="PCMT (E-value: 1.4e-43, bitscore: 147.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTAPLDSDSPQALRAGLVKQLRDQGAIRTDRVADVMGLVPRELF
                     APEAQLADAYDPQRAVVTKRDKDGLAISSVSAANVQAFMLEQANPQPGEKVLEIGSGGM
                     NAAYLAELVGSDGAVTSIDIDPEVTDRARRLLAESGYERVHVVTTDGEFGVPDRAPFDL
                     IEVTVGAPDIPPAWLEQLTPGGRIVVPLRVRGLMRSFVLVREGDHLVSRGYELCGFVPM
                     QGAGEQRERLVLLHDVPNEEVGLRLDNGDQVDVEALRAALASPRYEVWSGVTVGGEEPI
                     DDLDLWLATALDGHARLTATVGARDKGLVASASPLGLATLVAGSTFAYRTVRAVDESRT
                     RFELGAFGHGPAAAAAAAGLVKEIRTWDQDHRGGPGARIEVHPASTPDDRLPAGRVVDK
                     THTRISISWPGQQP"
     gene            complement(16810..17646)
                     /locus_tag="C2142_RS17700"
                     /old_locus_tag="C2142_17705"
     CDS             complement(16810..17646)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /locus_tag="C2142_RS17700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_17705"
                     /product="glycosyltransferase"
                     /protein_id="WP_148643545.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.7e-07,
                     bitscore: 29.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVDTTSFRPRALLPAERARVLAQAAMKPGQAGSNARGRHHVVSS
                     RGLPMLWTKDVQLRPVVVAIPEESELQFLPSLLDGFLKVGPPRLPEHLAPVLVLCPPTS
                     SSQPWPSADSDVIVAACDLEERPVLLAAADLFLASSAETTRAVYEAMATGLPVIGTTGG
                     SLEREITTGGHDANGWLADRGDTDALARAIVQACLYRPERLRRGTAAAEQIRNQARRDR
                     NGQSSQTSLPTPRPTALLGSGGERGSRGPACPTAARGPAQPGSLNPARTDTKESTS"
     gene            complement(17868..18377)
                     /locus_tag="C2142_RS17705"
                     /old_locus_tag="C2142_17710"
     CDS             complement(17868..18377)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17710"
                     /product="hypothetical protein"
                     /protein_id="WP_148643546.1"
                     /transl_table=11
                     /translation="MLTTAPRRPHPAPAHILGARWLASANRQAATAFTEWRAGQLAAIE
                     TGRRFNVVRVTDQRLGTAALQDMQLAGVVVGPVLLNRPRHAVEFLIALRQGEHWQMRDS
                     ELITRAIDGSPAVTVAMPAPGLPRTQGRTWLVPPDGRQFLTHPHNLANALRRARTQLRR
                     PPARRP"
     gene            complement(18397..18711)
                     /locus_tag="C2142_RS17710"
                     /old_locus_tag="C2142_17715"
     CDS             complement(18397..18711)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17715"
                     /product="hypothetical protein"
                     /protein_id="WP_148643547.1"
                     /transl_table=11
                     /translation="MTAYYSSGQPLRIWSGGAPDVRLAVRVLRRQVQRLAEQLELADDS
                     QPIAWLDSRDGYARAVDDLAAGRSHAVTFTHGYVTYVLTAAPSDGTEPRLPGRGVPCPA
                     "
     gene            complement(18876..19313)
                     /locus_tag="C2142_RS17715"
                     /old_locus_tag="C2142_17720"
     CDS             complement(18876..19313)
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="C2142_RS17715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_17720"
                     /product="ATP-binding protein"
                     /protein_id="WP_206670985.1"
                     /transl_table=11
                     /translation="MVAAEQPRTPRRWGATIKASPTTVSMARRRVRTVLEEWGLESERA
                     HDLVVICSELVTNAIRHASQEGDEVGLRLQEIDGGCRIEVLDSRPDLSLPKTSSPHGEN
                     GRGLILVRELADGMDVVTTCTTKKVQARVLLAAKDTSRSIP"
     misc_feature    19453..19471
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.01"
                     /tool="antismash"
     gene            19569..20912
                     /locus_tag="C2142_RS17720"
                     /old_locus_tag="C2142_17725"
     CDS             19569..20912
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17725"
                     /product="hypothetical protein"
                     /protein_id="WP_148643549.1"
                     /transl_table=11
                     /translation="MNTLFEALVTEAGMDFRSFLAEYRRVAALLYERTGDLAFRNVVLT
                     DKSFTRWRAGQVARPHHPAPAILKHMYSRPVDELFAPCTDEQIQVLRTAPTPVLDEREL
                     AMTARNARAHAADAASQLLPDLSLDQLEDDMVRLVRANTMTPPHVIFMQAKELLGLATV
                     MLDRTQVLSQRGRLYVVAGQASALLGACAFDLGSMPTAVELMRASALYGQVAEHGPLQA
                     YAHGYLALLFYWNGNPVHAVRQIERAQSFRGVGATGKARLAAIAARSYAHLGRAEEAHA
                     AIEQSLADRGPAVDDLHDGIAGEFDFSLERVAMSNSATLLLLRDGAGAEASARRSLELI
                     ASQSSESTPLVVAPQAGADLATALLMRRDLDGAADALGPVLSLPREWRGAGLVGRVNAV
                     RVELTSPAFRDAPLARSLAEQIDDFTLVAAPRILGPGAVRLAIDGSTS"
     misc_feature    complement(19570..19584)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.75"
                     /tool="antismash"
     gene            complement(20909..21937)
                     /locus_tag="C2142_RS17725"
                     /old_locus_tag="C2142_17730"
     CDS             complement(20909..21937)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963504.1"
                     /locus_tag="C2142_RS17725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_17730"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_148643550.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.7e-06, bitscore:
                     26.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILVLGGGWFLGRAVVSGALERGWEVTTFTRGLSGIQVPGAVAV
                     HGDRERAEDMARLAEHGPWDAVIDTSASELSPRAVLAGTRALEPVVGRYVYISTVSVYE
                     GWPSEPLTVDSPTLDAPADAGPEYGQLPEGWPGPDTHYGQQKAGAERAVTEAFGLTRTS
                     LLRPGVILGPGEYVGRLPWWLRRAERGGRILAPGDPAKSIQPVDVRDVAAFALDQVQRV
                     GHQVHNVTAPVGRETMDGFLQACMDVTSSSGELVWVTDEVLLRSGLRQWTEIPLWRTHP
                     GVWAIDSSSAIAAGFRSRPLSETVADTWTWLQQGNVPVPHQRWDEHGISPDKEDAILEG
                     VR"
     gene            complement(21998..22561)
                     /locus_tag="C2142_RS17730"
                     /old_locus_tag="C2142_17735"
     CDS             complement(21998..22561)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17735"
                     /product="hypothetical protein"
                     /protein_id="WP_148643551.1"
                     /transl_table=11
                     /translation="MSETKEYALQFVRTWAEAVVRQAERARAVRVRAARDSRNYEHMED
                     WSPTTEEIEANFREQWAEEHMLVWAAHQLERWEGRLRSERGQDPVEPDELLKNIRDALE
                     HLDEVDFKDGSAVPPSAAGGRVTGKALRRLPGEQLWIELHDGSSFEGVSPETVETHALA
                     VVRSIEDDLEQQLVDRCLDLLRDR"
     misc_feature    complement(22665..22680)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(22692..23144)
                     /locus_tag="C2142_RS17735"
                     /old_locus_tag="C2142_17740"
     CDS             complement(22692..23144)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS17735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_17740"
                     /product="hypothetical protein"
                     /protein_id="WP_148643552.1"
                     /transl_table=11
                     /translation="MATRKPPVKTAASPPKPQDTPEAGSATPPASPPGMELSAAAPLEP
                     PTAPPAPEPAPSPEPPTQPGITAHQPLVVDHTDLVGEDGNELPRDLAELFDLTHPEWTV
                     VYPRLRIYQRRTYTGSRRTVTQLLYTPAQSIPRAEFDQLQRALGGE"
     gene            complement(23144..24457)
                     /locus_tag="C2142_RS17740"
                     /old_locus_tag="C2142_17745"
     CDS             complement(23144..24457)
                     /GO_component="GO:0044423 - virion component [Evidence
                     IEA]"
                     /GO_function="GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /GO_process="GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01554.3"
                     /locus_tag="C2142_RS17740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_17745"
                     /product="phage major capsid protein"
                     /protein_id="WP_148643553.1"
                     /transl_table=11
                     /translation="MTADKNRLKELNAALRTKAAELDTISNAFTIEDGGVTVSTEKAAA
                     FRKTLGEAQAIKQLITDLEGAASIESFLNEPASQPYAPQDAALAARLGAGQAKSLGQRF
                     VDSDEFKALSAAGFRGSFDEMVTVDGHALDQLSKDIFSRSAGTASVLGLGTPERLEIVP
                     RAVRPGRVRDLFPSQTTTANLLYGVRVTGFTNAAGIVPERAMEVPPGGGAAVEVFARAG
                     QSNLTFKTVTYPVAEIAHTMPIHKNTLADEPRLRDLIDSEMVDGVKMAEDNEILYGPGG
                     DERITGIVNTQGVQTYAQVDPDKQSAAIRRAATRAFLAYFPPTGIVLHPFDFEDLELET
                     DNQGAYRVAVNVAVGAQKVVWRLAVVDSMAINEGKFLIGSFGLGARLYDREQVSVQIST
                     ENRDNFERGVVTVRGSERVGLEVPRPESFVYGTFKATP"
ORIGIN
        1 gcctcgcggc ggccgaaccg ggcggccgcg gtggcgtcga cgacctcggc cagggcgcct
       61 ccgtcgccgg cggccaggag gtgcgagcgg acggtgcggc gggagcgctg ccggggcccc
      121 ttgaggacgt cccggcccag gtagagcacg atgccggggt ggtcggtggc gcagaccgtg
      181 tcgggcacgt aggcgcgcag ccggtagccc tccatccgta cgtcggccca gccagcgccg
      241 gtgatggcct gcacggtctt gattagatcg ccgccggcgt cgtactgcgc ggtgtaggtg
      301 gtgggccagg gccgcccggc gctgtcggtg gcggaggtga agtcccaggt gacctcgggc
      361 agcgcgccgc gagcctgggc gcgctgcagc agggtggcga ggatcgcgcc agggctggcg
      421 ttgacgaacg ggaagtgcgg gtcgaggccg atgaccggcg cgccgggggt gtgcccggcg
      481 gggtagatca gggcacgctc cagcagggcg agggatcccc ggcagccgac ctggacgggg
      541 cgggcctcgc cgcccccgtc ggccgggtcg tcgccgtcgt cctcgaggag atatcgctcc
      601 ggccgttcgg tgccgtcgat gacgagcgcg atccgcgggt cgtcgccgga cagcagcgcg
      661 gcaccggggg cgttgcgggc gtaggagaag gtgagggctc cgggcccgtt gtgctcggac
      721 tggaccttca ggccgctcgg gtagggcagc agcccgagca ggggcccgct cgggctgtag
      781 acgcgcaggt ggatggccac agtggttgct ccggtgtcag gtcaggtagg cgcgacggcc
      841 ggtgacggtc agctgggtgc cggcgccggg gttggtaccg gtcaggcgca cgctcggcgg
      901 tatgccggga cggccggggg ccaggcgcag gaaggccggt ccggtgttgg tcaggcgcgc
      961 cgggtcgggg acgaggccgc cggtgccggt cagctgccag gtggcggagt ccacggtgag
     1021 ggactggccg gcggcgatct gcccggtgta ggtgaaggag tcgccgttgc ggccgggccc
     1081 gtcgctggtg tcggtgacgg tgggcgcggt gatcggcccg gtgatgcggt aggcgagctg
     1141 ctccatgggt gcggtggcgt ccgcgaacgg atcaaggtcg aggtcttgcg gcagcgggga
     1201 gccgggggcg gtggcctcga aggcgatgtc gccggactcc cagtagccgg cgggcacgtt
     1261 gacctccacg ccgacccgca ggccgttctg gccgagcggg gtgggcgcga gggcggacag
     1321 gacctcgccc tggcagcggc ggagctgccc ggctgcggtg taccgctcga aggtgagcag
     1381 ccggtgcggc cgggcgatgg cgcgcagcag gtcttcccat gcctgttcga cggcctgcca
     1441 gccgcccgct cgcggggcca gccacagggc gagggtgaac ttgccggggc cgtggtgctt
     1501 gggcctccac agctcaccga tccggttggg cacggcggcg ttggcgccaa caaccacggg
     1561 ggtcgtggcc aggccggacc ggtactccac gtcccgtacg aggccgtcag tgagttcgta
     1621 gccgtccacc agccaccgtt cgcgggccat caggcgctct ccttgtcgaa caggccgaag
     1681 ctcgcgaggg cacgcagccg gttgttgacg gtctcgcccg gggactccgg cagcgggttg
     1741 gtgatgtact gcacgatcgc gccgggcgag atgacggtgc cgatgcggtc gccctggccg
     1801 ccatcggcga gctgcccgcg ggcggcgttg agggcgccga cggccgaggt gccaccgaga
     1861 ccacgcacgg tctgcggcgt gaggacgcct tcgccggggc tgagccgggc cagggtggag
     1921 tcctggccgg gcgcgtaccc agggacgacg ccgccggtgg cgtagccacg gacgaaggac
     1981 agaacaccgt ccaccgcccg gttgaccatg ccccgcatca tgtcgcccca ggcgttgtcg
     2041 ggcatccagt tgaaccagct acgcaggggg ttgagggcct tggccagggc gccggcggcc
     2101 cagccccgta gccggtccat cgcgccgtcg acgatgccac cgaggaagta gccctggacg
     2161 ggcgcgccgg cgtcggccag gcggccggcg cgggcggcat cgttgagcgc ggtgatgccg
     2221 ccttctccgc cgagctgccg cacggcctgc gggatcagga cgccctcacc ggggctgagc
     2281 atcgccggta cggtgtcgcg gcccggggcg tagccgggaa cgacaccgcc tcgcgcgaag
     2341 ttgacggtga agctggggag tttgccgagg ccgaaggcgt cggcgaggga gttccacagc
     2401 cggcggatac cgccgtcgta gacggtgttg acccagaact tgatgggcca gccgaagacc
     2461 gtggtcaggg tcggccagat ccacttgacg aagtcgacga ggccctggag agcgatccgc
     2521 actccggaga cgaggccgcc gatggcggcg ttgaccacgt tgcggaacca ctccgatcgc
     2581 tcgtaggccg tgatgaaggc gacgaccagg gccgcgatgg cggtgatgat cagcatcagc
     2641 gggtttgcgg acagcgcgag catggccacc cggaccgcag cgatcgcgtt cgagaccgcc
     2701 ataagtccgg cggcgacgcc ggcgatcgtc agcagcgcgg acacgaacgc gcccatgccg
     2761 gggatcgaca gcagcacctc cacggcggac gcgacgccct gcatgaccag caggaacccg
     2821 gacaaggtgt tgcccaggcc gcccagctcg gcggcgatgt tcgccaccga ggtgatcagg
     2881 ccgagcagtt ggccccacag ctggccgttg ccgagcgccc cggccagctg catgaccgcg
     2941 ggcaggaact cggtgcgcag ccgggcgatc agcggggcga gcgccgggtt gttcgtgaaa
     3001 ttgaaccagg caacgccgac ggctgcgacc aggcggccaa gctcctggac gacggggacg
     3061 gtgttggcga agtacccggc cagcttggcc tgtgtctcgc cctcgccggt cagcgtgcgg
     3121 aagctgctgg cagcgctggc cagtgaggtg agcagggctt ggccggcggg ggcggcggcc
     3181 tggccgatgt ggaagacacc gactgcgatg tcccgcagga tgccccacag ctgcgctccg
     3241 gtgtccccgg cgcgctggaa gaacgcgccg agctggccgc cgtcccggcc ggcctgcacg
     3301 aaggcggcag cggcggccat gccgcgttcg gcggcgccgg ccaggcgctc cagcagcggg
     3361 ccggccgcga ccgtgatgtt gcgcaggaca tcggccgcgc tcaggccggc ggtcgcgagc
     3421 gaggcgatga cccgcgtgtt ggtcgcggcg atctgtgcca ggtccgcgcg ccaaggcccg
     3481 gaggtgacca tctccgcgcc ccggatcgcg acctggccga gtacctgccc ggtctgggcg
     3541 agcgcgctgt tgaagatcgg cagcagctgc atgccgcggg tgatggccgt ctccagcggc
     3601 ggcaggagcg cttcctgcgc ggtgtcccgc agcccgcgca gggccggctg gacggtgccc
     3661 tggagaaagc gggcgaagcg ctgcccggcc ggggacagct tgtcgagcgc ggcggcggcc
     3721 gcgttggccg ccgtgccgcc ggcagtcagc gcctgagtct ggtcccgcag agcccgcgcg
     3781 acgtcccgct gagcgtccgc tatctgctcg gcggaacgct tctgctggcg ctccgcatcg
     3841 cgaacggtgc ggtcgagctc ggtgtgggcg tcctggactt cccggacggc ctcgacgcgg
     3901 gagcgggcag cctgctgctc cgcgtcttgg acgccccgga cggcgtcctg ctccgcctcc
     3961 tgggctcggg tcagctcctg cttagcggcg gtgacctggt cgctgccctc gacgccttcc
     4021 tggttcgcct tcttgacgtc ctcggcgagc cgctgattgc ggacccggac gtcctcgagc
     4081 tggttggtgg cctcctggaa ggcgatctgc gcctcgcgcc ggtcggtctc ggacgcgaac
     4141 ggcgaggtgt tgacctcgtt gagccgggag cgggcctgct ccaggctgag caatgccttc
     4201 tgctcctcca gcggcccccg ggcggcgtcc cggttcaggt cctccaggga acgctgagca
     4261 tcccgccggg cgtcgttcag tgcttcctgc gcgcgggtcg ccgcctggtt ggcgcgggtg
     4321 accgtcagct cggccgccgc cagctgacgg tcggcagcgg ccacggcagc ggcggcctgc
     4381 tcctgaacgt ccgcgaggcg gcggcgggcc tgcgcgacct gctcggcccc gcgaagggac
     4441 tgctcgtcgg cgtcgcgctg cgcggcaccg aggcggcgct gggcgtccgc gacgcggtcg
     4501 gcggcggcct gcctggcctg cgcggcggcg ctggaggctc cggcggactg ggtatccgcc
     4561 tgcccgagag ccttcacggc ggcgccaatg ccgctgaacg cagccaggat ggtgccggcg
     4621 ccctgggcgg cggcgctcat cgctccgggc agcgcaccga gcagtccgac cgcaggggca
     4681 gcggccgcgc ccatggcgaa gaggccgccg gctgcctggg tgagggcctg gccgagcgcg
     4741 agcgcaccgg acgccatcgc gggtaggcgc atcagcccgg cgatggtgga ccccagccca
     4801 tcggcggcct cggcgaggcc gccgcccgcg ccgcctccgc cggtgttgat cgggatgtcc
     4861 agcgcgcggc ctgccgtcgt gcggaacgcg gcgacgcgcg cggcagcggc ggtcgtgtcg
     4921 acctcgacgc ggacgttgac ggacagaccg gccagcgccg cccgcactcg ggagcgcagc
     4981 ccggcggtgt cgacgtccag gccgaccttg accgtgttgg tggcggcttc gactgcgacc
     5041 tcgacgcggc ggcgcaggtt gccggtgtcg aacgcgacgc ccacccgcac gtaggcgccc
     5101 cgggcggtcg cggcccggat cttctcggcc aggcccgagg tgtcggcatc gaccgcgacc
     5161 ttgatacggg cgcgggcagc ctgggcggcg gcctgcacgc gctggcgcag cccggtggtg
     5221 tcgggctcca gccgcacccg cgcgcgcagg ttgcgggtcg ccgcatccac tcgggcccgc
     5281 gcgtcctgcg cgaacccgga tgaatcagcg gcgacctgga cgaccaggcg accggagtcg
     5341 atctcatccg tcaccgcggg gcgccttcct ggtagtgccg cgcaggacgg cgaccgcacg
     5401 agcgatcccg tccgcgtcgt gtccctgcgt gtggccggcc cgcagatggg ccgggcgggg
     5461 cagctcgacc ggctgccgca gacggcgctc cgccgccatc accgaaatca gctcgacggc
     5521 ctgcgcgagg agttcctgcg tcaggcccca acgatcggag ccgacttcgc cggcgtcacg
     5581 gcgcagcagc gcctcagcag gcagtccccg catcagggtc aggaggcggc gggtgccgag
     5641 gaatccaggg tcaccgggcc gtcgccagac gccccgggcg tcgaggtggt agaagcgctg
     5701 gaggtcggct tcgaggtcgt cccagcgttc gaaggcgtct cggacggccc gatgagttcc
     5761 cccaggcccg cacccccgcc catgtacttc gtccaggcgt agcgcaccag ctccagcaca
     5821 tcggagtgac tgggccgctc ggccatcagc cgggtgtagc cgtcctcacc aagcaggcgc
     5881 cggcccatct cccccgcagc ggcgatcagg tcggacggaa ggcccggctc cgaaccgagg
     5941 acgtccacga tcaggccggc ggcctccgcc tgctgctcac ccttcgactg ggcggcctcc
     6001 accagcttgc gcagcagcag cggcaggtac gggatcccga tcagcggctg ccacacctcc
     6061 aggggcagtt cggccggcag gagcgccacc tgggcgccgc cgaggatgat cggctcctcc
     6121 ccgactgtgt actcggcctt cgcggcgcgc gccttgtcgg cggcggcggc cagacggcgc
     6181 gtacgtgcgg cgtccagatc gatcccgggc attcagggct cctcggtctg tcgggcgagt
     6241 gatcgccgca gacgctagga gcgggccagg gttagcgtcg ccccgagacg ctggccagaa
     6301 acgggacgag ggggcccgtg aacgcggcgg aggggcccac gcctggcgtg accccctccc
     6361 gggtgcagat cggccgctaa cggcggccta cacgggcctc agggccgcgt acagccactc
     6421 cagcgcggct cccaacgctt cgggctgcgt ggtgtacagc cgctcccgcc actcgtccct
     6481 tccggcccat ccgtcggtct ccgaggacca ccgccagccc ggaccgcacg ggccccactc
     6541 gcacatgcac gactcggtgt agaagaccct cacccgccgt cgggcccacg gccggattcg
     6601 tgcgcttccg gacgcgatcg cctcgacccg gcctcccggg cgctgctgaa tgccgtacca
     6661 gcccggcgcc agctgcacga gcgtgccgaa ccgggtgtac tcgccctcct ggtcgagccg
     6721 gacgaacgtc ccttccgggt aaggcagttc catggttcct ccccatgcct gttgtggtcc
     6781 ggccagcctc agcggcggcg gccggcgctg ggcacagcga agccccggcc ggggggggtt
     6841 ggccggggct tcgcggaatg cagccgggcc caccctgggg ggtagggcgg ccgggctgac
     6901 accaccacag taggtgcacg agccacccat gggcacagcg gcaagaacgc caacttcgtt
     6961 ggcaggaagg acgttcaggc ggtcggggcg aacccgggat cgtcggtgag gtcataccag
     7021 gggtcaccga cggcgccgcc aatgaccttg agctccagcg gcagcgtgga ctccgcgtcg
     7081 ttggggaact tctggttcac cgaggccacc tgctcgcaaa gcggcacgat ccgccggtag
     7141 tgcttggccc cgtcgatcag ctcgatcacc gccgcgaact ggttacggcc acccacagcg
     7201 ggcggcgtgt accggtagaa cgtcttcccg cccgcagtga cgctggtgac cgcgccaccg
     7261 ccgtacaccg ccacgatgtt ggtggcgttc cactcctgca gctcgacctt ggccgtcgca
     7321 gcgtcctcgg tctggatggt gcgggccgcg taccgaagct gatgagactt gatctcctcg
     7381 aacttcgggt cggtgttcca ctccagcgac ccgggcttga acaagcccac gtccttccag
     7441 gcggccggca tggccacgat cggatcggcg ggcgcgacgg tacccggcac cgccaggtac
     7501 agccgcgcca tctgggcgac gaacatgctc tccgtaggca cgaacgatct ctcctcgggg
     7561 cggaccggta ggtgtgccgg accgtaggcg cccgccggcc gtagcgtcgc gccgtccccg
     7621 cacgggctgg gcggcccctt gtccgcgcgc gtggggctgt cgcagaagtc gcgaaatccc
     7681 gtggttcagc cggcggcggg atgggccgtc agcgccacga ccccgaggta ccggccctgc
     7741 ccggtcggct cgggcagcca ccctccggtg gacagggcct gtacggcggt caccaccggc
     7801 tgtcccggca gcgcgggccg cacggtcagc tcgtgcagcg ccttcaccgc ggtgctgaac
     7861 gccaggtgca gcgcgggccg ggccgtggag cggtcgagat cgcccagggc ctccacctgg
     7921 atgtggaacg tgccgagcca gcgccagccg gcggcggctc cgccggggat ctgcgtgatg
     7981 cggatacgtg ggtagggcgg tgcgttgcgc gccccgatcc ggcccttgcc gcccagcacg
     8041 cccgtcagct cctcgtggtt ggacagccag tccaccacga ggagttcggc gtcgagggag
     8101 gcgagatcac gcactcggct tggcctcggc cttgtccgcc gagggcttgg cggcgagctg
     8161 cttgcgggac ggctcgggcg ccagggcctt cgctacggcc tccgggtcgg acgggtcgac
     8221 gccggccacg taccccgaag cgatgagctg cctggcctcg tggtgcggca cctcgatctc
     8281 gtcgccgggg gccagggccg cgccgtcgcg ggtcaggtgg tgggcgaggg tgatccggac
     8341 gttgctggcc atgggggctc cttcaggacg ggatgggatg acccgccgaa ggaaagcaag
     8401 ccgaggcggc taccgtcccg ctgtgccgga tgcggcacgg ccgtcgggcc ttgcgggtgc
     8461 tgtcagcggt ggcgggtggc gacctgcgcg gcggccctgc tcatgaagtg cgtgccctca
     8521 ccctgcgcga actcggcatc ggcggcgccc gggaagtcgc aaacgacctg ggcctcggca
     8581 cgcgagccgc gaatggcggc cttgcccgca gtgatggacg cggcaacggc ctcggggtcc
     8641 tcggtgacgg tgcaccggca gccggcagtc tcctcaatcg gcccgctcgg gtcgcgagga
     8701 ccagcaagca gagcaccacc cacgttgaac ggcaccggag cagcccgggt ctgcccgtca
     8761 gcgtcccggt gactgggccg tgcgtgcccg tcttcacgtg tgtgccaggt cttcgcgcca
     8821 ggcgccagcc gccgggcttc gacagccacc tcttccgcaa ggcgctcggc gcgccgggcc
     8881 agcagtgggg ccagccggtc cgcgatatcg ggcggcagtt cgagccgtgc catcagcggt
     8941 gtccttccgg tcgggtgccg cccgcaaccc gaggccgggc cgtcacacgc acgtaggtga
     9001 gggcggggtc caccgcgttg cgcagctcgt cggctgccag cacggtccac tcggcgccgg
     9061 tggctggctc cgccacgatg tctccggcga gcaggagtcc cgcccgcggg tccacggcca
     9121 gaagccaagt gccgtccgtg tggggttgag cgcggccagg ccacgggcca cgcagttcac
     9181 cgggcggccc agtcgtctcg tctccgtacg cgtcgagcac gggcatgccg cgggtgcgca
     9241 cgccgagctg ccgggcggcg agcaggacgg ccatcacagg ccgcccgtgc cggggatgcc
     9301 tcggatcgtg agcccgggcg gggtgggccg tactggggcc tggtagaccc ggcggccgcg
     9361 cagccgccat cggtccgtcg tggccaggtc tgggggcgcg agcagggcgg gcggttcggc
     9421 ggcggtgtcg taggtgacgg actggccctc gacggaggcg gaggagatgc ggcgctgccg
     9481 ggccggcgcg tcggccagca gcgggtgatg gcaggcggtg gcccgaagcc acaggcgtag
     9541 cggggcggtc tccggcatgg agcgggcgtc gatgccggcc aggtaccgga cggtgtaggt
     9601 gggcgcgccg atgccgaaag ggccgggcgg agagttgggc tccgaggtcg cggacaggac
     9661 ggtgacgacg ggggcgtggt gcaggatcca gccgtctggg ccagcgtgta ccccggtctc
     9721 ggtgtactca gcggggagca atggccggcc aaggtgggcc acgagggcgt cttgggcgtc
     9781 ctcgatggcg gtctcgatcc gttgacgcag ctcgtcgacg aggggcgttg ggtagccaag
     9841 gcgccgagcg acgtcctccg gcgtgacgat cagctccact gcattcctcc ttcaccggct
     9901 gtcggaggct gacgttaggc agcggctgag attgtgtcgt cctggccccg acggccggtg
     9961 gtgcgcgttg tgattgccga tgcgggtgac ggcgtcctta tcaggcgtcg cgcagcggcc
    10021 cgagtacgtg gttgcgagcg gcgcgggcaa gagcgccttg ggtggctgtc gggatgccgg
    10081 ctctgttcca gtgaaagatc accatgtgcg cgaggacggc gcgcaggcct cgggttaggt
    10141 ctccggtccg ggccgctgcg gcgagggctt gcccagcggt gtggaactcg taggcccacg
    10201 tggcggcgta ctccagacgc gctccgggcc gagcaagagc gccggtgtcg gctgacagga
    10261 gcgtgccgac gctagcggtc agccggtcca ggtcgtcggt ggcagtctcg gggaggggac
    10321 gcatgtgtgt gacgcgatcc cagacgtctc cctgctcggt ccattcctga ccggccgcgc
    10381 gaagcatgtg gctgcacagc atcatcgaga gctcgcggcg gccgatcacc gggcggggcg
    10441 agtccgtgtt gcgccagtgg gtgtggacga ggatggcgcg gctgtcggcg tggaagagcc
    10501 ggtgggcggc ggcgatgccg tgggggcctc cgagggcggc ggcctcgggt tcgtagatgc
    10561 cgggccacca ggccgtgatg acgtcttgct cgcgtagtcg gtcgagtagg cgggccgtcg
    10621 ctttctggaa gtcgtcggcg gtcgcggcgg ggcctcgctg gaggcggagg cgccagcagg
    10681 ggtgtttgcg gacgtaccac caggcgtgca cggcgccgct gttctcggcc tggcgcaggt
    10741 gggggccgag atgggcggcg aggtgctgct ctgcttggtc ccagtccgcg ggttgtacgt
    10801 acacctggat ccaggctccg gtggctgctg cggtggtctg ggtggtgagg gcgttcagcc
    10861 cggccgcccg gtagaggtcc agtgcgtctg tcagctcgtt ggggctcagg ccggccaggg
    10921 cagcagcctc aggtagcggg gtgccgctga gggctgacaa gacggctttc tcggcctggt
    10981 gcggggcggg tgcgtcggtc atgggttcca gtccggttca ggagagcagc aggcaggcgt
    11041 cccagctggt ggtgggtgcg cctcctcggt cggtggcgtg gagggcgagc gctgttcctg
    11101 cggtgccgtc gaggaagcct ggctgccggg ccggaacctg cgcgtggagc agcgctcgaa
    11161 gggccggcag gtgggcggtg aactggtcgg ggcgggcggc atcctgggcg acgcggtgaa
    11221 cggtgtggag caggccggcg gcgccgtggc ataggccggg ttcgccgatc tgcgcgagct
    11281 gggcagggtc ggtgatgcag cgcagcaggg cgtgttcggc agccttcttg cggcggtcgt
    11341 cgccgagggc agtggcggcg agctgctggg cgcgggccag gccaggggtg ccgtagcacc
    11401 agctcggccg acgagggcct tcctggaaga cggttgtgag gcggtgttcg tcggcggtaa
    11461 cccattgcgg ccaccacggt ccggccggga cgtcctgccg caggccgtcc agccaggcca
    11521 ggatgcgcag catggcgtcg gcgtggccgt ccacgagcgc gcccgcgctt tttgcgaggg
    11581 cgagcagagc gagggggccg gtgatgccgt gggcgagacc gaggttgccg tggccgcccg
    11641 ggaacgcgcc ggaggtgcgg ccggacgggt cgtggcgcac ccaccagccg ggcaggtcgc
    11701 tgccgggaag aggctgggtg aggcgtacga ggtaggcgag gacatcgtgc agggtgtcgc
    11761 tgcgcgggtc gcgctgcaga aggtaggcgc cgagtccggt cagcccgtac agcaggtcgt
    11821 attcggaggc ggtggtgtgc tcgccgcggt cgatgcgggc gtgggcctgg tcgaggcggc
    11881 gcgtcgtgag cttggtgacg gccgcgtcga gggtgcgcag ggtgtcgcgg tggtggccgg
    11941 tggtgccggc tgcggtgttc aggacgaaag cgagggcggg ggcgccgacg aacaggctcg
    12001 cgtcgtcgga ggcgatgagc gggctcgccg cgatgctgac cagccactcg cggacgctgg
    12061 cccagctgcc gacgccgatc tcggcgcgtt cgatgtgcag cagggtgatg ccgacagcgc
    12121 cggtggcgag ggcctgcgag tgctggatgt cgtcgggccc gcacggcacc accggccggg
    12181 aggcaggggc ggtcgggtgc gggtgggcgg tgcgtgcggt catcaggtgg ctccgtgggt
    12241 gcgggtggtc caggagaggg cggcggctcg ggccaggcgc cggcatgcgc gttcggcgtc
    12301 cggggcgatc cctgcggctc ggatgtggtg catgtgaagc agggacgtca ggacggtgtc
    12361 tgccggcggg ccgtcgagga cgatgaggcg gcggcggtac gcgtccaagg cggcgcggcg
    12421 ccgcgcccag gcttcggtga tgcccgtccc ggtggcggcg cgcagggcgg cccaggtgtc
    12481 ggccgggtct gcgagggcga cggcctgggt gagcagcgtc cggtccgggg cggaagcggg
    12541 ggtacgggcg aggttgtcga tgagccagcg catcccggcc tcggtgccgc cgaggaagct
    12601 ggcggcgatg tcggtcatgc tcgcggcggt gagcgcgggg gccgggagcc ggccaggccc
    12661 ggtgtgctgg agctgggcga ggaccgcggc ggagtccgcg acgaacaccc actccgcgag
    12721 gccgagcagc tggccctcgc cgtagcggcc ggtctcgggc cagtaggtgt cccactggac
    12781 ccggccggtg gccaggccgg cgtcggccag gttctggacc cagatgccga cctgacgggc
    12841 ggtctcggcg aagccgccgt ccccgtggcg aatccgtagc cgtaggtgcg ggtcggggtc
    12901 ctggtagcgg atgaaccacc acggcgattc cccgaaggtc gcggtcagtt cgggtaggcg
    12961 tgccaaaagg tcggtgtggc gggccgcgtg ggcatacacc ttcgcgtacg cccaccccgg
    13021 gcctggagcg cccggagagc ggcccggggc gggcgcggcg gggtgccggg gcgcgggcag
    13081 gcgaacaggc tcctgggtgg agacgagcgg gatggtgagt tcgtgcgcgc ggccaccgat
    13141 ccagcccagg gcactgggca cgggtgcctc tcgcaggatt gcccggccgt gctggtcgag
    13201 gtgggcgcgc aggagctgcc ggtggtggcg ctcggcgagg tcgagccgta ggcgctggtc
    13261 accgtcgccg aggtcgaggg tgtcggccat cagccggcgt tcgcgtagcg aggccagcgc
    13321 gttgtcccag tcccgccacg aggctgcagc cggaggaaga tcggtgccgt gcaggcgcca
    13381 tcgggccggg gcaaggatgc tgcgcccgtg ccggacagca ggcaggtagg gcagcttccc
    13441 ggcggctggc ccccaggaga acggcgccag gacggcagcc cgggcccggg gcagttcggc
    13501 caggaagcgg accagcgggt gggtgaagtt gctcagctgc actgcgttga ggacagcggg
    13561 ctcgaccggg cggccggtga ggcgggagac cagccatatg cgtcgggcgt cggcggtgac
    13621 cgcgaggtcc gccagcgcca tggtgccctg ctcgtgctcg gcgaccgtga tcgtctcggt
    13681 caggacggca ggagtgcggg cgacgttctc ggtgcgcacg cgcagcggcg ggctggagag
    13741 ctgggcgcgg acggcgccgg cggcgagcgc cggcgctcgg cgaagcgccc cggccatgcg
    13801 gcggcggtcg gcgctgtcga gcaggtacag gaaccggccc gtcgtggttc ctgcgccttg
    13861 ggcgaggccg gtgacgacga gcgtgaacag tccgtcgtcc agctgggcct gggaatcgct
    13921 gtggagttgg aagcacagct ccaggtgggc gggcgtctgt tccaccggtc cgttcgccag
    13981 gcgtggaagc acatcggtca cgtccaccac cgccaagccg tcgagcgcgg ccagctgcgc
    14041 gacctcgagc agcgtggcat cgcggtcctg catggctggc ggttcgacag gcagcgggga
    14101 accgcggtac ccggccgggt agccgagccc tgtgtcgggc ttgacgaggt ccagcagggg
    14161 gacgtgcgcg cctgggccgt agcgctccag gaagcgaccg tggtagtccc tccaggcggg
    14221 cgggccttgc gggtaggggc tggcgagtgc cagggcatcg gccgcgcgct cggcttcctt
    14281 ggccacgcac gccggtatca ccagggcgca gtccagccgt aggtccacgg ccagcagcgg
    14341 cgtgacgtca ctgggtacag ccgccatgat gttcagcgcg tccaggcggg agctgccctg
    14401 ccgtgcgggg tcctcgccgt tgtgccgctc taggcggctg tgcagagcag tgagcaggcg
    14461 cacggatggt tccacggagc cgaggtcggc ggccccgacg tgcccgagct gggccaggac
    14521 gtggccgagc gggtcggagg cggtcatggg cggccgtagc gaggtgatga gcatgcgctg
    14581 ctccacgagc tgcatgacca gccggtcgat ggctccgggg ggagcgtccg ggaactcggc
    14641 gcccaccttc tggaccagtt cctcgagcgg cacagcgtcc cgggcagcgg ccaggatcgc
    14701 cgcgaccggc ggggtccggc gcgccgacac ttcctgaggc gcgtcaccgc ctggtggcgg
    14761 ctgacggcac ggcagcacga gctgatcgcc gcgcacctgg caggtcgcat ccgcgatcac
    14821 cagcaggcgg cgtaacaggg ttccctcggc ctccaggcga ttcacgacgc cggccagcca
    14881 ggccgcgtct ggccgcgcgg ctgcgcggtg cctaccggcc caggagacct caaggctgtc
    14941 gcccagccga gcgggcgcga cgccggcgaa cagtccgaag ggcgtcgccc ggtgccgcat
    15001 ccgcaagacg tagcgcacca aggactcccc gagccggcgc agctggcggt ccgaggtgat
    15061 ccggccggcg caggccgctc gcacccgtga ggcgaggacc gggctcgcca gatccacggc
    15121 gccggccgca tcgggactcg cccacgcttc tgccagccac cgctgccacg cggcgccgtc
    15181 cggcgggtcg tcgccgctca ggtctggcca tggcccgatg gccgtctcgc tgtcggcggt
    15241 ggctcgcagc agaaccgcgt ctacggcccg gaacatccct gccccccagt ctctacgtcg
    15301 gttggtcgga tcacccggcg tgccggggcc cggctgggcc ccggcacgcc gctcggtcag
    15361 gcgacgcagg tgctgttgga acaggcgctc gcgcaggtct gcccgcagcc gtcgtcggtg
    15421 ctgctcatca gctcggcgat gaccggaccc tgctcgacga gcgtgacgtc cagctcgaag
    15481 tcgttgatct gggtgttctt catgtgcgat tcctcctcgt ggagttgccg gaatgacagg
    15541 tggtgccaac ctggcccttg gtcttgccgg tctacggctg ctggccgggc caggagatcg
    15601 agatgcgggt gtgggtcttg tcgaccacgc ggcccgcggg gagtcggtcg tcgggcgtgc
    15661 tggcggggtg gacctcgatg cgggcgccgg ggccgccccg gtggtcctga tcccaggtgc
    15721 ggatctcctt caccagcccg gcggcggctg cggcggcggc cgggccgtgg ccgaacgccc
    15781 cgagctcgaa gcgggtccgg ctctcgtcca cggctcgcac ggtgcggtag gcgaaggtgc
    15841 tgccggccac gagcgtggcg agaccgaggg gcgaggcgga cgcgacgagg cccttgtcgc
    15901 gcgcgccgac ggtggcggtc agccgggcgt gaccgtccag ggcggtggcc agccacaggt
    15961 cgaggtcgtc gatcggctcc tctccgccga ccgtgacccc cgaccacacc tcgtaccggg
    16021 gtgaggccag cgccgcgcgc agagcctcga cgtcgacctg gtcgccgttg tccaggcgca
    16081 gcccgacctc ctcgttcggc acgtcgtgca gcagcaccag gcgttcgcgc tgctccccgg
    16141 cgccctgcat cggtacgaag ccgcacagct cgtagccgcg gctgacgagg tggtcgcctt
    16201 cgcggaccag aacgaaggag cgcatcaggc cgcgtacgcg cagcgggacg acgatccgcc
    16261 cgccgggtgt cagctgctcc agccaggccg gcgggatgtc gggcgcgccg accgtgacct
    16321 cgatcaggtc gaacggggcc cggtccggga cgccgaactc gccgtcggtg gtgacgacgt
    16381 ggacccgctc gtacccggac tccgccagga gccgacgggc ccggtcggtg acctcagggt
    16441 cgatgtcgat gctggtcacg gcgccatcgg agccgacgag ttcggcgagg taggccgcgt
    16501 tcatgccgcc ggagccgatc tccagcacct tctcgcccgg ctgcgggttc gcctgctcga
    16561 gcatgaacgc ctggacgttg gcggccgaga cggagctgat cgccagcccg tccttgtccc
    16621 gcttggtgac gacggcgcgc tgcgggtcgt aggcgtcggc gagctgcgcc tcgggggcga
    16681 acagctctcg gggaaccagt cccatgacgt cggcgacccg atcggtgcgg atcgcgccct
    16741 ggtcgcgcag ctgcttgacg aggccggcgc gcagggcctg cggggagtca gaatcgagcg
    16801 gagcggtgtt caagaggtgc tctccttcgt gtcggtacgc gccgggttca acgagcctgg
    16861 ctgggcgggg cctcgtgctg ctgtcggaca ggcggggccc ctcgatcctc gctctccgcc
    16921 gctgccgagt aaggcagttg gacgcggcgt gggcaaggaa gtctgggagg actggccgtt
    16981 acgatcgcgc cgggcctggt tgcggatttg ttcggcggct gccgtgccgc gtcgcagccg
    17041 ctcgggccgg tacaaacacg cctggacgat cgcgcgggcg agggcatcgg tgtcccctcg
    17101 gtctgcgagc cagccgttcg cgtcgtggcc gccggtcgtg atctcccgtt ccaggcttcc
    17161 accggtggtg ccgatcactg gcaagccggt ggccattgcc tcgtagaccg cgcgggtggt
    17221 ctcggccgag gaggcgagaa agagatcggc ggccgcgagc aggaccggcc gttcctcgag
    17281 gtcgcacgcc gccacgatca cgtcgctgtc ggcggacggc cagggttggg acgagctggt
    17341 gggcgggcac agcacgagca ccggggcgag gtgttcagga agacgtggcg gtccgacctt
    17401 caggaacccg tcgaggaggc tgggaaggaa ctgcagctcg ctctcctcgg ggatggcgac
    17461 gacgaccggt cgcagttgca cgtccttggt ccacagcatc ggcagaccgc ggctggagac
    17521 cacgtggtgc cggccccgcg cgttcgaccc tgcctgcccg ggtttcatcg ccgcctgcgc
    17581 gaggacccgg gcccgttcgg cggggagcag cgctcgtggt cggaacgacg tggtgtcaac
    17641 gagcatggtc gctgtccttg ggcctgtcgg gatggttgag ggggctgggc cagcggcccc
    17701 ggggggcgct gcgtgttcgc gagcgcgcgc ccgcgcccgg ggaccgccgg ctgcgggtcg
    17761 gccagtggga ggtggccaag cccgcccccg gtcctcgggg gttagtgggg accggggtgg
    17821 agccccgtcc cggccagtgg agccgccaac tggtcgggac gggggactca gggacgccgc
    17881 gcggggggcc ttcgcagctg ggtgcgggct cggcgtagcg cgttggcgag gttgtgcggg
    17941 tgggtgagga actggcggcc gtcgggcggg acgagccagg ttctgccctg agtgcggggc
    18001 aggcccgggg caggcatcgc caccgtgacc gctggcgaac cgtcgatagc tcgtgtgatc
    18061 agctcggagt cccgcatctg ccagtgctct ccctggcgca gggcgatcag gaactcgacg
    18121 gcgtgccggg ggcggttgag caggacgggg ccgaccacga cgccggccag ctgcatgtcc
    18181 tggagcgccg ctgttccgag gcgctggtcg gtgacgcgaa cgacgttgaa ccggcggcca
    18241 gtctcgatcg ccgcgagctg gccggcgcgc cattccgtga acgcggtagc ggcctgccga
    18301 ttggccgacg cgagccaacg cgcgccaagg atgtgggcgg gcgcggggtg ggggcgccga
    18361 ggggctgtcg tgagcatcgc gctcgtcctt cctgggtcag gcggggcagg ggactccgcg
    18421 gccgggcagg cgcggctccg tgccatcgct gggcgctgcc gtgagcacat aggtcacgta
    18481 gccgtgggtg aaggtgacgg cgtggctgcg gccagcggca aggtcgtcca ccgcccgcgc
    18541 gtagccgtct cggctgtcga gccaggcaat cggctggctg tcgtcggcaa gttcgagttg
    18601 ctcggcgagc cgctggacct gccgccgtag cactcggacg gccaggcgta cgtccggggc
    18661 gccgccactc cagatccgca ggggctgacc cgagctgtag taggcggtca cggtgcacca
    18721 gaacggctct ggaggtgacc aggggcgatc gcgaacgaag acgctctggc ccttgcctgc
    18781 cccgtgagtt gcctgcgagc gggacggcgg gcgagtcgtc ggggccgggc ggcggggccg
    18841 gccgacggcc ctcagggccc gacggatcgc gctcttcacg ggatactcct tgacgtgtct
    18901 ttggcggcga ggaggaccct cgcctgcacc ttcttggtcg tacaggtcgt cactacgtcc
    18961 atgccgtctg caagctcgcg tacgagaatc agtccacggc cgttctcgcc gtgcgggctg
    19021 gaggtcttcg gcagtgacag atccggccgg gagtccagga cctcgatccg gcagccgccg
    19081 tcgatctcct gaagccgcag tccgacctcg tcgccttcct ggctggcgtg tcggatggcg
    19141 tttgtcacca actccgagca gatgacgaca aggtcgtgtg ctcgttcgct ctccaacccc
    19201 cactcttcga gtactgtgcg cacccgtcgg cgcgccatgg agaccgtggt cggcgacgcc
    19261 ttgatcgtgg ccccccagcg gcgaggggtt ctcggctgct cggcggccac catgtgcatc
    19321 gctcccgtca tcaggagcgt gtggacgccc cgtccttggt tcgcttgcgg ggatcaacca
    19381 tggaccggca gcggagacat aaccaccgcc gaagcgccga cacttggctc ccgttcaggt
    19441 gagccgagag acaaactgtg gacagttcgc agacacttct ccacggccta tgggatcacc
    19501 ggccccgcag tggtaggcag ggtgatgaag tagttcgcag ctggggctgc ggccccgaag
    19561 ggaccgcgat gaacacgctg ttcgaggcct tagtcaccga ggccggcatg gacttccgca
    19621 gcttcctcgc cgagtacagg cgggtcgcag cgctcctcta cgagaggacc ggagatcttg
    19681 ccttcagaaa cgtcgttctg acggacaaga gcttcacgcg atggcgcgcg ggccaggttg
    19741 cccggcctca ccacccggcg cccgcgatcc tcaagcacat gtacagccgg cccgtggatg
    19801 aactcttcgc gccctgcacc gacgagcaga tccaggtgct gcgcacagcg ccaactcctg
    19861 tgctcgatga aagagaactc gcaatgaccg cacgaaacgc ccgtgctcac gccgctgacg
    19921 ccgcctcgca gctgctcccc gatctcagcc tcgaccagct cgaggacgac atggtgcgcc
    19981 tggtccgggc gaacaccatg accccgcctc acgtgatctt catgcaggcc aaggagctgc
    20041 ttggcctcgc cacagtgatg ctcgaccgta cgcaggttct gtcccagcgc ggtcgcctct
    20101 acgtcgtcgc cggccaagca tcagcgctgc tcggtgcctg cgcattcgat ctcggttcta
    20161 tgccgaccgc ggtcgagctg atgcgcgcct ctgccctgta cggccaggtg gcggaacacg
    20221 ggccgctcca ggcgtacgct cacggctacc tggccctgtt gttctactgg aacggcaacc
    20281 ccgtccacgc tgttcgccag atcgagcggg cccagtcgtt ccggggagtc ggcgccacgg
    20341 gcaaggcaag gctggccgcg atcgctgccc gctcctacgc gcacctgggc cgcgcggagg
    20401 aggcccacgc ggcaatagag caaagcctgg ccgatcgcgg ccccgctgtg gacgacctcc
    20461 acgatgggat cgccggagag ttcgacttca gcttggagcg cgtcgccatg agcaacagcg
    20521 cgacgcttct gcttctccgg gatggcgccg gcgcggaggc ctccgcacgg cggtcgctgg
    20581 agctgatcgc ctcccagtct tcggagtcca caccgctggt ggttgcccca caggctggtg
    20641 cggacctggc gacggccctg ctgatgcggc gggacctgga tggcgccgcc gacgcgctgg
    20701 gtcccgtgct gagccttccg agggaatggc gcggggctgg actcgtcggc cgggtgaacg
    20761 cggtccgagt tgagctaacg tcgccggcct tccgggacgc tcccctcgca cggagcctcg
    20821 ccgagcagat cgacgacttc acgctggtcg ccgcaccgcg gatcctgggc ccgggcgcgg
    20881 tgcggctcgc catcgatggc agcaccagct agcggactcc ctccaggatg gcgtcctcct
    20941 tgtccggaga aattccgtgc tcgtcccagc gctggtgcgg cacaggtacg ttgccctgct
    21001 ggagccaggt ccacgtatcg gcgacggtct cggaaagcgg ccggctgcgg aagccggccg
    21061 cgatcgctga cgacgagtcg atggcccaaa cgccggggtg ggtccgccag agggggatct
    21121 ccgtccactg gcgcagaccg ctgcgaagca ggacctcgtc ggtgacccac accagctcgc
    21181 cggagctgct ggtcacgtcc atgcatgcct ggaggaagcc gtccatcgtc tcgcggccca
    21241 ccggtgcggt gacgttgtgg acctggtgtc cgacgcgctg gacctggtcg agcgcgaagg
    21301 cggccacgtc ccgcacatcg actggctgga tcgacttcgc cgggtcgccg ggcgcaagga
    21361 tgcgtcctcc tcgctcagcc cggcgcagcc accaaggcag cctgccaacg tactcacccg
    21421 gcccgaggat gacacccggc ctgagcaggc tcgtgcgggt gaggccgaag gcctcggtca
    21481 ccgcgcgctc ggcgccagcc ttctgctgcc cgtagtgggt gtccgggcct ggccacccct
    21541 cgggcagctg tccgtactcg gggccagcgt cggcaggggc atccagtgtg ggcgagtcca
    21601 cggtcagagg ctcgctgggc cagccctcgt agaccgacac cgtggagatg tagacatacc
    21661 ggccgacgac cggctccagg gcccgggtgc cggccaggac agcacgcggc gacagctcgg
    21721 aagcagaggt gtcgatcacg gcgtcccacg ggccatgctc cgccaagcgc gccatgtcct
    21781 ccgcccgctc ccggtcgccg tgcaccgcga ccgctccggg cacctggata ccggacaggc
    21841 cgcgcgtgaa cgtggtcacc tcccaccctc gttccagcgc gccgctcaca accgcccggc
    21901 ccaggaacca gccaccgccc agtacgagaa tcctcatgcg ggcgatcctg ccagtcccgc
    21961 tccttggtgc gcagccgccc gcgggatcgg gtgtcgatta ccggtcacgg agcaggtcga
    22021 ggcaccggtc aacgagctgc tgctccaagt cgtcctcgat ggaacgcaca acggccaggg
    22081 cgtgggtctc caccgtctcg ggggagaccc cctcgaagct gctgccgtcg tgcaactcga
    22141 tccacagctg ctctccgggg agccggcgta gtgccttacc ggtgacacgg ccacccgcag
    22201 cgctcggcgg caccgcgctg ccgtccttga agtcgacctc atccaggtgt tcaagggcgt
    22261 ctcggatgtt cttcagcagc tcgtccggtt ccaccgggtc ttggccgcgc tcgctccgga
    22321 gtcggccttc ccaccgctca agctggtggg ccgcccagac gagcatgtgt tcctcagccc
    22381 actgctcgcg gaagttggct tcgatctcct ccgtggtggg gctccagtcc tccatgtgct
    22441 cgtagttcct gctgtcccgg gcggccctca cacgtacggc ccgtgcccgt tcggcctgcc
    22501 ggaccaccgc ctccgcccac gtgcggacga actgcagcgc gtactccttg gtctcactca
    22561 cctcgcgagg ctatggcacc cgggcgcggc ggggtcgatc tggtcgtaga ggtccgggcg
    22621 ccgccgccag cggctggaca gccggaagcc cgtccccagg ttcggggacg ggctcgtgac
    22681 tgcgaccggg gctactcccc gccgagggct cgctgaagct ggtcgaactc ggcccggggg
    22741 atggactggg cgggggtgta gagcagttgg gtgacggttc gccggcttcc ggtgtaggtg
    22801 cggcgctggt agatccgcag gcgcgggtag acgacggtcc actcggggtg ggtcaggtcg
    22861 aacagctcgg cgaggtcgcg cggaagctcg ttgccgtcct cgcccacgag gtccgtgtgg
    22921 tcgacgacca ggggctggtg ggcggtgatc cctggctgcg tcggcggctc gggactgggc
    22981 gccggctcgg gtgcgggggg cgccgtcggc ggttcgagcg gggcggcggc cgacagctcc
    23041 atgccgggcg ggctggccgg cggcgtagcg ctgccagcct cgggggtgtc ctgcggcttg
    23101 ggcgggctgg cggccgtctt cacgggcggc ttgcgggtgg ccatcagggg gtcgccttga
    23161 aggtgccgta gacgaaggac tcggggcggg gcacctcgag gccgacgcgc tcggagccgc
    23221 gcacggtcac gacgccgcgc tcgaagttgt cgcggttctc ggtggagatc tggacggaga
    23281 cctgctcgcg gtcgtagagg cgggcgccta gcccgaacga gccgatgagg aacttgccct
    23341 cgttgatcgc catggagtcg acgacggcga gccgccagac gaccttctgc gcgccgaccg
    23401 cgacgttgac cgcgacgcgg taggcgccct ggttgtcggt ctccagctcc aggtcctcga
    23461 agtcgaaggg gtggaggacg atgccggtcg gcgggaagta ggcgaggaac gcccgggtag
    23521 cggcgcgccg gatggcggcg gactgcttgt ccgggtccac ctgggcgtag gtctggacgc
    23581 cctgggtgtt gacgatgccg gtgatcctct cgtcgccgcc cgggccgtag aggatctcgt
    23641 tgtcctcggc catcttcacg ccgtcgacca tctcgctgtc gatcaggtcg cgcagccgcg
    23701 gttcgtcggc gagcgtgttc ttgtggatcg gcatggtgtg cgcgatctcg gcaaccgggt
    23761 aggtgaccgt cttgaaggtc aggttggact ggccggctcg cgcgaacacc tccaccgccg
    23821 cgccaccgcc gggcggcacc tccatggcgc gctcggggac gatgccggcc gcgttggtga
    23881 agccggtgac ccgcacgccg tacagcaggt tcgcggtggt ggtctgcgag gggaagaggt
    23941 cgcggacacg cccgggccgg acggcgcggg ggacgatctc cagtcgctcc ggggtgccga
    24001 ggccgaggac ggaggcggtg ccggcggacc ggctgaagat gtccttgctg agctggtcga
    24061 gggcgtggcc gtcgacggtc accatctcgt cgaacgagcc gcggaagccg gccgcgctga
    24121 gcgccttgaa ttcgtcggag tcgacgaacc gctggccgag gctcttggcc tggccggcgc
    24181 cgaggcgggc ggcgagggcg gcgtcctggg gggcgtaggg ctggctggcc ggctcgttga
    24241 ggaaggactc gatgctggcg gcgccctcga ggtcggtgat cagctgcttg atcgcctggg
    24301 cctcgccgag ggtcttgcgg aaggcggcgg ccttctcggt ggagacggtg actccgccgt
    24361 cctcgatcgt gaaggcgttg ctgatggtgt cgagctcggc ggccttggtg cgcagcgcgg
    24421 cgttgagttc cttgagccgg ttcttgtcgg cggtcacgag gtgacgctcc ttggggttgg
    24481 gccgggccgt cccgccagtg cggggcgaag gggtgtcacg tcgtgcgccc ggtcagcacc
    24541 ggtgcgccac ggcgatcggc acaccgtagg agcggcccgt ccttagtgtc gcgtcgagcc
    24601 gccgcctgtt ggcgggcatc cgttttcgcc ccgctctcgc gccataactc ttgtgccggt
    24661 cagcgaagtt gggtgtgccc agggtgggtg aggttggtga ctgtggagag cggtcccgca
    24721 gagcgttgga cggctgggcc agggctcggc cgataccgac accgacgatc ggagtcccga
    24781 cgtgtatccc ttcccccgtc ccgacctgcc gcagataccg ggagaccttg acctggctgc
    24841 ggcggcgccg gccggtcagc caggcagcga gctggctgtg gccgggaccc ggtaccaggt
    24901 gctctcctcg ggcgcgggct gggtgctgcg cgttgccggg cctggtggga agacggcgct
    24961 gtacgggccg tgcgcggtgg aagggcgagc ggaggcgtgg atgcaccagc tcgctgcgtg
    25021 gtcgctgtgg ccgatggcgc aggtgcgtgg gacctggggc tgcctgacgc gaacggacga
    25081 gggctggttc acggccctgg ccttcccgct cctcacgccg caggtgcaga tccatgcgga
    25141 cgttcgggcc gccgaggaac acgccgccgg ccacctgatc gctccggccg tctggtcgga
    25201 cgccgcagac tcgggtctgc cggatgcggt gcggcgggtc gaggagcagt tctgggtgcg
    25261 tgagggctac cgggtc
//
