LOCUS       NZ_CP026498            28235 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. CB01881 chromosome.
ACCESSION   NZ_CP026498
VERSION     NZ_CP026498.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CB01881
  ORGANISM  Streptomyces sp. CB01881
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     A 3-hydroxy-3-methylglutaryl-CoA synthase gene based probe for the
            discovery of the acyltransferase-less polyketide synthases
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2018) Xiangya International Academy of
            Translational Medicine, Tongzipo, Changsha, Hunan 410000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002953255.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 02:39:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,978
            CDSs (total)                      :: 7,904
            Genes (coding)                    :: 7,565
            CDSs (with protein)               :: 7,565
            Genes (RNA)                       :: 74
            rRNAs                             :: 5 (5S)
            complete rRNAs                    :: 5 (5S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 339
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 339
            Pseudo Genes (frameshifted)       :: 124 of 339
            Pseudo Genes (incomplete)         :: 251 of 339
            Pseudo Genes (internal stop)      :: 10 of 339
            Pseudo Genes (multiple problems)  :: 45 of 339
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:44:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2233997
            Orig. end                         :: 2262232
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026498.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28235
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /product="melanin"
                     /region_number="15"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /rules="melC"
                     /tool="antismash"
     cand_cluster    1..28235
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /detection_rules="melC"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-iv"
                     /product="melanin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22595
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22595
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12595](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12595
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            475..1827
                     /locus_tag="C2142_RS09745"
                     /old_locus_tag="C2142_09715"
     CDS             475..1827
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951371.1"
                     /locus_tag="C2142_RS09745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09715"
                     /product="glycosyltransferase 87 family protein"
                     /protein_id="WP_241002476.1"
                     /transl_table=11
                     /translation="MLIHRADRRPSVRQLTDPTGLFRRRAGWFAGWLAAAGWAGAFPFL
                     SGLAPHRGWGAVAATGYLAAAVAVLVVPWRRARPVSVAVAAAGAVVVPLLGLALTGRGQ
                     SEVTVIERSAALLLEHGSPYLAEPLTVTDYTPYLPAMALLGLPRALLGADGWPARLLGD
                     ARLWCAAVFLGCLWATGRPYRRGIALLAASPLVALPLCVSGVDLPMTGLCCLALALAAR
                     GRPGGAGLALALACSLKWTAWPAVAVAAALLAATAGRRAALRGTAVAVAGTAALVLPVA
                     MRSPGPLVRQVFAFPTGRGGLPTPAGSPLPGRLLADLGPAGWYAAVGLLLLAGLAVAGS
                     LAVHPPRDAAGAADRLALGLCLAFLLAPAGRFGYLALPLVLVVWARVPAGPRPSPRTAP
                     VPRTAPALGAPPASPHSTHSAHSTDRRTEVAPTPWPPHSSSPMTSRPGRAA"
     gene            1773..2996
                     /locus_tag="C2142_RS09750"
                     /old_locus_tag="C2142_09720"
     CDS             1773..2996
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984915.1"
                     /locus_tag="C2142_RS09750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09720"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_148642022.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 4.3e-35,
                     bitscore: 119.7, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTLVVTNDFPPRQGGIETFVHALATRLPAGEVVVYTSAEPGAA
                     AYDAGLPFPVVRDRSRMLLPTPRVTRRAAEIARANGCDRVWFGAAAPLAAMAPGLRRHA
                     PGIGRTVATTHGHEIWWARTPGARRLLRRIGDNVDVVTYLGEYTRTRIAPALGPRARLE
                     RLVPGVDADLFRPAGDGARADGPVVLCVARLVPRKGQDVLIRALPLIRRAAPGTVLVLV
                     GRGPDERRLRALARRHTEPGSVVFAGGLEHAATAAHYAAADVFAMPCRTRRAGLETEGL
                     GIVFLEAAAAGLPVVAGRSGGAPDAVLDGVTGTVVDGRSPAAVAAAVGRLLRAPATERA
                     RTGAAGRRWVQQEWSWETSARRLAGLLDPERADAHQPDAAHRDADQRDAERPAPDRASS
                     DATYSPRR"
     gene            complement(2978..3634)
                     /locus_tag="C2142_RS09755"
                     /old_locus_tag="C2142_09725"
     CDS             complement(2978..3634)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984914.1"
                     /locus_tag="C2142_RS09755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09725"
                     /product="response regulator transcription factor"
                     /protein_id="WP_148642023.1"
                     /transl_table=11
                     /translation="MLRIVIAEDAVLLRAGLVELLTRGGHRVVAAVGDARALAAAVDAD
                     RPDVVVTDVRMPPDFHDEGLRAALELRDRHPGLPVLVLSQYVATPYATRLLGAAGAQPA
                     GLGYLLKDRVGEVADFLDALRRVAAGQTVIDPDVVRVLLRQQSTERPLARLTPREREVL
                     GLMAEGLNNQAIGGRLSITEASVVKHCGNIFMKLDLDPAVGNRRVLAVLAHLRGE"
     gene            complement(3622..4947)
                     /locus_tag="C2142_RS09760"
                     /old_locus_tag="C2142_09730"
     CDS             complement(3622..4947)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008407455.1"
                     /locus_tag="C2142_RS09760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09730"
                     /product="sensor histidine kinase"
                     /protein_id="WP_148642024.1"
                     /transl_table=11
                     /translation="MGGKRADEGQQPVAVLAALRARPLRFLRSSTPWRCWAHVLSGAVL
                     GLLLLVVLAVLLAAGLALSVVGVGLLVLPAVAVSGLPVGALERRRLRLVEPVPVPDPHR
                     PLPGAGRRARLRTRLRERATWRELGYTALFALPLAAADLGLTALLVFSATLVCAPVVVW
                     ALAPETVMLIPGQAIPGPVEALPATAVGLAGLLLCAYAGTLLTVGRVRLVRFLLGPRDE
                     DPGRQVLELTRSRARLVDAFEAERRRIERDLHDGAQQQLVALSMTLGLAAYELGGSSGG
                     DGGDGRAAALVERARDEARQALEQLRGLVRGIHPQVLTDHGLAAAVTEVALRHPIPVAV
                     DIDLPARLPGPVETTAYFTVTEALTNAAKHSGAAAITVHGRVEGGRLVVQVTDDGRGGA
                     DPAAGAGLQGLADRVAILRGRLMVTSPIGGPTRLRVEVPCSG"
     misc_feature    complement(4947..4965)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.24"
                     /tool="antismash"
     gene            complement(4957..5934)
                     /locus_tag="C2142_RS09765"
                     /old_locus_tag="C2142_09735"
     CDS             complement(4957..5934)
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013088.4"
                     /locus_tag="C2142_RS09765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09735"
                     /product="DMT family transporter"
                     /protein_id="WP_208693219.1"
                     /transl_table=11
                     /translation="MALSAIWGASFALIKVAVDVGVPPLWVACWRCVLGAAALWAILAL
                     RREPAPRDLATWGHSAVAALLLNAVPFALFSYGETRVSSVLAGVVNATTPLFTLVFAVL
                     VVPGERRPGPRRLAGLGLGFAGVLTLLGVWRGPGPGGVTGGLACLAATCCYGAGFAYLR
                     RHLSGRPHSATGLSAVQIACAAAESALVAPFAAGAPRWPGAGPAAALLALGALGTGVAY
                     ILNLTLVRTAGTVVAAAVTYVTPLWSTGLGALLLAEPVGWNALLGGLAVIVAVALTRQP
                     AAPDPAAATAAPAVPAVPAVMATSPGSPASTAPTAAPKGRQTVG"
     gene            6173..7048
                     /locus_tag="C2142_RS09770"
                     /old_locus_tag="C2142_09740"
     CDS             6173..7048
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006601747.1"
                     /locus_tag="C2142_RS09770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09740"
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="WP_148642026.1"
                     /transl_table=11
                     /translation="MASEVNLAQLRALIAVADAGGFGAAASELGISQSAVSHAVAALER
                     TLGAPVLHRTAPARPTPLGEQILPHARTAVASAAAVRTIATRHSGGLTGTVRLAAPTTV
                     CQGLLPGLLRDWRAAHPRLTVSVFEGEDDELAVWLEAGTVDAAVLVDADPVPPGSVALG
                     ADSMHALLRRDHPLAGEPAVDVADLEDDDFLLSEGGCERHIREAYRRAGVRFAPRHRIR
                     DLNTLIGMVHAGVGVSVMPALAQPMLPADCVLVPIRPAVHRSLTLTGPGGRPWSPAVNG
                     LLAAVRSARS"
     misc_feature    7132..7147
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.37"
                     /tool="antismash"
     gene            7344..8558
                     /locus_tag="C2142_RS09775"
                     /old_locus_tag="C2142_09745"
     CDS             7344..8558
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983597.1"
                     /locus_tag="C2142_RS09775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09745"
                     /product="carbohydrate-binding protein"
                     /protein_id="WP_241002477.1"
                     /transl_table=11
                     /translation="MVAAAGVLGLVAGGLAALAGSGSAVAAVDAASAATGLGSNWYASA
                     PYLMPEDNSPPDAAAVMDATGQKAFQLAFILDKGGCSPAWGGTSSIDTDTAMPAVIQTI
                     RAKGGDVSVSVGGYGGTKLGQTCGTPEATAAGYQKVVTKYGLKAIDFDLEEPEYENTAA
                     IRNEIGAARILQRDNPGLYVSITTAGTNAGTGWFGQQMLNEAKSQGFTPDNYSIMPFDG
                     GFNGAAAQTNALVRFNQILQTTFGWTEANAYAHEGVSLMNGRTDAAEYFRQADFQAVLD
                     FALAHKLARYTYWSVNRDRQCPGTVDPGLSGSCSSVAQNDWDFTKFTVRFAGATPPTTP
                     PTTPPPTSSSPGACTDPAWSAATTYTGGAKVSYGGHKYHAKWWTLNENPSAGGQWGVWS
                     DDGPC"
     gene            8750..8977
                     /locus_tag="C2142_RS09780"
                     /old_locus_tag="C2142_09750"
     CDS             8750..8977
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS09780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_09750"
                     /product="hypothetical protein"
                     /protein_id="WP_148642027.1"
                     /transl_table=11
                     /translation="MSSDFRASGSALDETILHDAVLRESPIFARLALLWLDAGRMVPGR
                     PDQEWRHLTEPPQLFRLGRTAVALHPGEDA"
     gene            8974..9447
                     /locus_tag="C2142_RS09785"
                     /old_locus_tag="C2142_09755"
     CDS             8974..9447
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016564.4"
                     /locus_tag="C2142_RS09785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09755"
                     /product="SsgA family sporulation/cell division regulator"
                     /protein_id="WP_148642028.1"
                     /transl_table=11
                     /translation="MTCPETPRIPSQRRPAGSCAVPLELRAVVCPGITVSVAACLRYDP
                     AEPYAVYLDNHTDLDEPITWMFARDLLAAGMDAWAGTGDVSVHPGTGATSQTLFIALGG
                     ENGTVVLRAEAAPVKAFLTATERIVPFGAEPRHLDLDGLLHRLLEERPPEPDR"
     misc_feature    complement(9712..9726)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.7"
                     /tool="antismash"
     gene            9838..9999
                     /locus_tag="C2142_RS09790"
     CDS             9838..9999
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014134222.1"
                     /locus_tag="C2142_RS09790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SflA family class IV lanthipeptide"
                     /protein_id="WP_174315602.1"
                     /transl_table=11
                     /translation="MPTAVINEIRDAGPLVVDDEFILFEDDDRSDHDATACLADPWVTA
                     TTRFACDL"
     gene            10001..12595
                     /gene="lanL"
                     /locus_tag="C2142_RS09795"
                     /old_locus_tag="C2142_09760"
     CDS             10001..12595
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010475729.1"
                     /locus_tag="C2142_RS09795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09760"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_148642029.1"
                     /sec_met_domain="Pkinase (E-value: 4e-20, bitscore: 71.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.6e-19, bitscore:
                     67.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTESIAGRSGWSDDTWSYLNDPRMPAMDHGWKLHVSARPGDLEAV
                     TGLVLPVLSRHVCHAKWARSPETLREINSGVSSAGAVGKAITVYPAPGVLVGLADELVA
                     VLRGREGPQIVSDRRVDPAAPVYYRYGPFTGDYRTGRSGRLESVMVGPDGRAFDGLADG
                     SYRCPPWAEDPFENRPGHDAGPRSSAGFGGGRYRVTGGIVRKPQGNVYRAVDLATGQPV
                     VVKQARAFVAEDESGADTRDRLRNERTVLAALDAVPGVPRALDYFRHRSDEYLVMTSCG
                     GRDLRREVQENGPYRPDPARPSRTVPDLAAQLLRVLDGIHLRGVVVRDLKPGNVVLDAT
                     GRCRVIDFGISALDGVGPDGSTPGYSGPVRRGTGGTAEPADDYYALGATLCFAATGMEP
                     VIVDADDAVNRDRTLDCLAWALPGDDHRWIRAGIAGLMSFDPAVRTAGADRLRAGAPVA
                     ASGVPAAAASGVSRPSRGPGRLRFDDGLAEEVVEHTAAFCVDEARRIADPVLAARANIP
                     TPVDVYGGSSGLGLELLHHLHRPGVRETVDALAQWTTGQSRNLSPGFYSGRTGVGLFLA
                     EAGAGPGGHADHPDHPDGPDLPARGPDGGPPEADLIEGVAGIGIGRLLLARHAFADGDS
                     RLADRHLAVAAACDRMLASGRARLTPAGADGIGSAALREGFAHGEAGVAYFLVEYAGAT
                     GDPAALHRARRACADLAAVTPGIIAAAAGPGATRRYGSWCRGLAGIGTVLVRAADRLGE
                     PGHLVLAQRAARTCAALAPRMPLVNQCCGLAGVGDLMVDVARASGSEEFWNAAETVAAL
                     ILSRSGGTPSRPVFPDAGLARSSATWAGGSAGVLAFFRRLHDRGGQRLGLVD"
     gene            12750..13583
                     /locus_tag="C2142_RS09800"
                     /old_locus_tag="C2142_09765"
     CDS             12750..13583
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574917.1"
                     /locus_tag="C2142_RS09800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09765"
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_148642030.1"
                     /sec_met_domain="PIG-L (E-value: 3e-28, bitscore: 97.9,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDRPLTLMAVHAHPDDEATGTGGVLARYAAEGVRTVLVTCTDGA
                     CGDGPGGVKPGEPGHDPAAVAAMRRQELKASCEVLNVGHLELLEYADSGMMGWPANDAP
                     GSFWRTPVEEGAARLAELMRHYRPDVVVTYDENGFYGHPDHIQANRITMAALAMTGMSP
                     KVYWTTAPRSMMQRFGEVMREFGADWEEPDPAEAAAMPEIGLPDEEITTWVDTTEFGGQ
                     KFDALAAHASQGENIFFLKMGKERFTELMGVETFVRVADPTGVAVPENDLFAGLR"
     gene            complement(13725..>14681)
                     /locus_tag="C2142_RS41970"
                     /pseudo=""
     CDS             complement(13725..>14681)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606769.1"
                     /locus_tag="C2142_RS41970"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="chitinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="DTCPTKPKPPGKVLQGYWENWDGAANGVHPGLGWVPITDSRIAAH
                     GYNVINAAFPVILSDGTVLWQDGMDAGVKVSTPAEMCQAKAAGATLLMSIGGAAAGIDL
                     SSGTVADKFVATVVPILKKYNFDGIDIDIETGLSGSGNINTLSASQANLIRIIDGVLAR
                     MPAGFGLTMAPETAYVTGGSVTYGSIWGAYLPIIKKYADNGQLWWLNMQYYNGSMYGCS
                     GDSYQAGTVQGFTAQTTCLNNGLTIQGTTIKVPYDKQVPGLPAQPGAGGGYMAPSLVGQ
                     SWNAFGGSLKGLMTWSANWDGSKGWTFGDNVRSLQGR"
     gene            complement(<14841..15632)
                     /locus_tag="C2142_RS41975"
                     /pseudo=""
     CDS             complement(<14841..15632)
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014116.4"
                     /locus_tag="C2142_RS41975"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="carbohydrate binding domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSRNPAIGPDLLTGPAAPPTIRSGTAPHVPHLTQSRAPRPRRSCP
                     WRPAGREHSMFRRRSRTPRLSGHHRPCPDPARLEGGRTGSEPPRVPRPHRATVERAPQV
                     NRTSPAKNGPTVLKRSLAGVSATAVIGAVIGAGIAVAGSVTAGAATTNLVANPGFENGL
                     SDWTCSGGSGAAVSSPVHSGASALRATPTGQDNAQCAQTISVQPDSQYTLSAYVQGSYV
                     YLGATGSGITSAPSTWTPSSPSYGRLSVGFTTGPSTTSVTVY"
     misc_feature    15599..15614
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.19"
                     /tool="antismash"
     gene            complement(15811..17355)
                     /locus_tag="C2142_RS09810"
                     /old_locus_tag="C2142_09775"
     CDS             complement(15811..17355)
                     /EC_number="1.4.-.-"
                     /GO_function="GO:0015930 - glutamate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016638 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568102.1"
                     /locus_tag="C2142_RS09810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09775"
                     /product="FMN-binding glutamate synthase family protein"
                     /protein_id="WP_148642032.1"
                     /transl_table=11
                     /translation="MQARKIGAAAATAVALLAARDLVQKRHALLRNFPVIGHARYLLET
                     IGPELRQYIVTSNEEERPFSRDQRTWIYASAKEENNYFGFGTEVDVEHVQGHAYLKQRT
                     FAGHLPDAHDPQASLPSAKVLGGPRGRAKAFRPASVVNISAMSFGSLSGAAITALNKGA
                     ALAGTMHNTGEGGLSPHHRNGGDLVLQLGTAYFGCRNEDGTFNLDKLKDVVAGAPVKAI
                     EIKLSQGAKPGLGGMLPGAKVTPEIAGIRGIPVGEDCASPSRHTAFSDVDSLLDFVELI
                     ATETGLPVGVKSAVGEMGFWQELAALMARGDRGVDFVTVDGGEGGTGAAPRIFADSVSL
                     PFRMGFSRVYGTFAELGLTDDLTFIGSGKLGLPENAAVAFALGVDMINVAREAMLSIGC
                     IQAQKCHTDKCPTGIATQNPWLARGIDPASKADRAAAYLRTLRRELMKVSAAVGVAHPA
                     LITPDDIEIMNGDYEARTLAGVYGYKDGWGELGPHLADEITALLTAGPAPVRKPAV"
     misc_feature    17839..17854
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.39"
                     /tool="antismash"
     cand_cluster    17843..28235
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    17843..28235
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[22842:23235](-)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(22843..23235)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
     gene            complement(17918..20134)
                     /locus_tag="C2142_RS09815"
                     /old_locus_tag="C2142_09780"
     CDS             complement(17918..20134)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058808.1"
                     /locus_tag="C2142_RS09815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09780"
                     /product="PAS domain S-box protein"
                     /protein_id="WP_148642033.1"
                     /transl_table=11
                     /translation="MEERFRALLEAAPDAMVIADDAGVITLVNAQTEALFGYPREELLG
                     RPVELLVPMRFRGQHHRHRDEYAANRQVRPMGAGLELHGLRKDGTEFPVEISLSPLETA
                     DGLLFSAAVRDVSDRKAAEARFRALLEAAPDAMVIADDAGVITLVNAQTEALFGYPREE
                     LLGRPVELLVPMRFRGQHHRHRDEYAANRQVRPMGAGLELHGLRKDGTEFPVEISLSPL
                     ETADGLLFSAAVRDVSDRKAAEARINELAALVESSQDAILAKTLDGRITYWNAAAHSLY
                     GYTAAEALGRHVAMLAPPEHREEITALLKRLGDGEKVEHFETLRVTRTGRLIDVDVTLW
                     PTRTADGTVTGACAIVRDISDRKRAEAELTALYEQQRHIALTLQRSLMGTPPAIPGLAT
                     ASRYLPATQGAGVGGDWFDLIPLGAGRVGVLIGDVMGRGLEAAAVMGQLRSAAHALAKT
                     GMEPRRLMQALDAAVTDLELPDQLVTCCYLVIAPDTGEVTICSAGHLPVLLAVPGETIR
                     ALPAPVSAPLGVGGIPHQQACLAVPPGATLLLYTDGLVETPGGDIEAQITELAATVDRA
                     FTGDGGLEAVADHVLSAVLPDSDGHNDDVTLLLLQLPAAPLATATTDLPTVPSSVGEAR
                     AFLTKTLTAWGCAERTDDACLLLSEILTNSVQHGRGPIDLLLRRTSTELTVEIGDRSSQ
                     LPHPRLATSEEESGRGLIIVDALADGWGVRPSGSGKTIWFTVRL"
     misc_feature    complement(20313..20328)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.88"
                     /tool="antismash"
     misc_feature    complement(20320..20333)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.86"
                     /tool="antismash"
     misc_feature    complement(20342..20351)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.04"
                     /tool="antismash"
     misc_feature    20883..20896
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.82"
                     /tool="antismash"
     gene            21304..21780
                     /locus_tag="C2142_RS09820"
                     /old_locus_tag="C2142_09790"
     CDS             21304..21780
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675203.1"
                     /locus_tag="C2142_RS09820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09790"
                     /product="hypothetical protein"
                     /protein_id="WP_148642035.1"
                     /transl_table=11
                     /translation="MKPRTAATVAALTVAGLAVSAPTAGASGTKLSQSAAAGQFSSAGI
                     TWSSSGGCTTRSNSTCTSFEQINSGTVNAIITLKRASGCAINITGGTEVGHASGTYSHY
                     NGYKVDIARNSCIDGYIQNSFTYIGYRGDGYPQWKAASGNLYCNEGNHWDILVY"
     gene            complement(21967..22794)
                     /locus_tag="C2142_RS09825"
                     /old_locus_tag="C2142_09795"
     CDS             complement(21967..22794)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038020.1"
                     /locus_tag="C2142_RS09825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09795"
                     /product="tyrosinase family protein"
                     /protein_id="WP_148642036.1"
                     /transl_table=11
                     /translation="MAVRKNQATLTPAEKRAFVNAVLELKRRGAYDAFVSTHNDFIMSD
                     TDTTERTGHRSPSFLPWHRSFLLRFEQALQAIDATVTLPYWDWTTDRTPDSSLWGPDFL
                     GGDGAGTGGRVATGPFAQSSGSWTLTVRPDSRNYLIRQLGRAGENLPTRADVDAVLAIA
                     TYDAAPFNSSSAGFRNSLEGWVGVNVHNRVHVWVGGTMSTGMSPNDPVFWMHHCMIDRL
                     WAGWQSRHAGQGYQPVRRTRNVVALNDTMKPWNDVTPADLLDHTKFYTYDSAY"
     gene            complement(22843..23235)
                     /locus_tag="C2142_RS09830"
                     /old_locus_tag="C2142_09800"
     CDS             complement(22843..23235)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019762077.1"
                     /locus_tag="C2142_RS09830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09800"
                     /product="tyrosinase cofactor"
                     /protein_id="WP_148642037.1"
                     /sec_met_domain="melC (E-value: 7.7e-43, bitscore: 144.9,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEDTTTEITRRRMLQGAVVASALAAGTVVLGLTGPAVAPASGAD
                     TESGESFDEVFRGRRIQGMPMSGDGHHAMSGYMVLIDGRELHMMRNADGTWISVINHYQ
                     TFTTPRALVRAAVNALSGADLAPLAA"
     misc_feature    23426..23439
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.13"
                     /tool="antismash"
     gene            complement(23650..23994)
                     /locus_tag="C2142_RS09835"
                     /old_locus_tag="C2142_09805"
     CDS             complement(23650..23994)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024935.4"
                     /locus_tag="C2142_RS09835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09805"
                     /product="transposase"
                     /protein_id="WP_162002433.1"
                     /transl_table=11
                     /translation="MDPGEVEKPREHLGAFVAEVFASRARKDRRRQGDCHPQGLMPDGW
                     RTSIQPIAERLPDGNMRALRRFVSQSPRDHAPVLRRIVRGMTSALAPEEWVVDDDSFPK
                     AGEPLRWRAG"
     gene            complement(24227..24583)
                     /locus_tag="C2142_RS09840"
                     /old_locus_tag="C2142_09810"
     CDS             complement(24227..24583)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS09840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_09810"
                     /product="hypothetical protein"
                     /protein_id="WP_148642039.1"
                     /transl_table=11
                     /translation="MRTAVRLAAVTAVAAGSLGLSTGVASADATYPANVPGCAGGMNVQ
                     YYNGHDWVQGYVISTTGNYCTVNLQQSNGRWSSAYSNVRGDKHYTLQLQDSGITSYVVV
                     CNTDLGRCATSASY"
     gene            complement(25178..25906)
                     /locus_tag="C2142_RS09845"
                     /old_locus_tag="C2142_09815"
     CDS             complement(25178..25906)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677015.1"
                     /locus_tag="C2142_RS09845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09815"
                     /product="flavodoxin family protein"
                     /protein_id="WP_148642040.1"
                     /transl_table=11
                     /translation="MSAPPPAPPRRHDDLRALVINCTLKRSPERSHTQGLIDVSTGIMQ
                     RQGVQVDVLRAVDHDIATGVWPDMTEHGWETDDWPVLYSQVMAADVLVLAGPVWLGDNS
                     SVMKKVIERLYACSSILNSEGQYAYYGRVGGCLITGNEDGAKHCAMNVLYSLQHLGYVI
                     PPQADAGWVGEAGPGPSYLDPGSGGPENDFTNRNATFMTWNLLHLARMLKDAGGIPAHG
                     NQRSEWDAGCRFDFENPEHR"
     gene            complement(26131..26859)
                     /locus_tag="C2142_RS09850"
                     /old_locus_tag="C2142_09820"
     CDS             complement(26131..26859)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039623.3"
                     /locus_tag="C2142_RS09850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_09820"
                     /product="DUF5995 family protein"
                     /protein_id="WP_148642041.1"
                     /transl_table=11
                     /translation="MTQSRTRSAQSVEEVVERMRAIKDRLDPRDGVACFNRMYLRVTEL
                     VGERLQAGYFHDQAFIERLDVVFANLYFDAVDAAEAGSPVNASWQPLFEARDNRVVWPV
                     QFAFAGMNAHINHDLPLAVVSTCIERRTTPDTPPVHADYLKVNELLAQVEAEVRASFEV
                     QVLRAATGATEPLKHIVASFSIARARDAAWATTQILWHQRNLRPFYDATLATVTAGAAL
                     AGRLIVTPVLPPVDRPDGGA"
     misc_feature    complement(27284..27294)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    27521..27536
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
ORIGIN
        1 ggcccgggcc cttcgtccag ttgtcgaccg ccaccgtgcc gacgggccgc ccgccggttt
       61 cgtccagcac ccagtagcgg cgccggtaca gctcgccgtc cggccactcc cggccgctct
      121 cgccgagccg ttcgcgcagc acccgctcgg cgtccgcgcc cagctcctcg gggtcgaccg
      181 gctccgccag ttccccttcg gcccgggacg cgaggtccca gagcgcgaac cgccggtcgt
      241 ccccctcctc caccgcccgc agccggggcg ccgaccccag ccgctcctgc gcccgctcca
      301 ccgccgcatc ccaggacctc accacggagt ccacgatatc gggccgcggc caccgaacgt
      361 gactcgatca ccaccgaacg tcagcacgaa cggggttgat ggtaggggaa acccgacccc
      421 gggtctcgac ctggccgtca tgaccccgcc cggccgcgcc gctgcaatgg aagggtgctg
      481 atccaccggg ccgacaggcg gccctccgtc cgacaactca ccgaccccac aggcctgttc
      541 cgccgacgag ccggctggtt cgccggctgg ctcgcggcag ccggctgggc gggcgcgttc
      601 ccgttcctct ccgggctcgc gccgcaccgc ggttggggcg ccgtcgcggc gaccggctat
      661 ctggcggcgg ccgttgccgt gctcgtggtg ccctggcggc gggcccggcc ggtctcggtg
      721 gcggtcgcgg cggccggcgc cgtcgtcgtc ccgctgctcg ggctggcact caccgggcgg
      781 ggacagagcg aggtcaccgt gatcgaacgg tcggccgctc tgctcctgga acacggctcg
      841 ccgtacctgg ccgagccgct gaccgtcacc gactacaccc cctacctgcc ggccatggcg
      901 ctgctgggtc tgccgcgcgc cctgctcggg gcggacgggt ggccggcccg gctgctcggc
      961 gacgcccggc tctggtgcgc cgcggtgttc ctcggctgtc tctgggccac gggccgcccg
     1021 taccggcgcg ggatcgccct gctggccgcc tcaccgctgg tcgcgctgcc gctctgcgtc
     1081 agcggggtgg acctgccgat gaccggtctc tgctgcctgg ccctcgccct cgccgcccgg
     1141 ggccgcccgg gcggggccgg tctcgcgctc gccctggcct gttcgctcaa gtggacggcc
     1201 tggccggcgg tcgcggtcgc ggccgcgctg ctggccgcca cggccggccg gcgggccgcg
     1261 ctgcgcggga cggccgtcgc ggtggcgggc acggccgccc tggtgctgcc ggtggcgatg
     1321 cgctcacccg gtccgctggt gcggcaggtg ttcgccttcc ccaccggacg cggcgggctg
     1381 ccgacgccgg ccggcagccc gctgccgggg cgactgctcg cggacctcgg cccggccggc
     1441 tggtacgccg ccgtcggcct gctgctgctc gccggcctgg ccgtcgccgg ctcactggcg
     1501 gtgcatccgc cacgggacgc cgcgggcgca gccgaccggc tggcgctcgg gctctgcctg
     1561 gccttcctgc tggcacccgc cggacggttc ggctacctgg ccctgccgct cgtgctcgtc
     1621 gtctgggccc gggtacccgc cggcccccgc ccctctcccc gtacggcgcc ggtcccccgg
     1681 accgcgccgg ccctcggcgc cccaccggcc tccccacact ccacccactc cgcgcactcc
     1741 accgatcgcc gaaccgaggt tgcaccgacc ccatggccac cacactcgtc gtcaccaatg
     1801 acttcccgcc ccggcagggc ggcatagaga ccttcgtcca cgccctggcc acccggctgc
     1861 ccgccggcga ggtcgtcgtc tacacctcgg cagaacccgg cgcggccgcg tacgacgccg
     1921 gactcccctt cccggtggtc cgcgaccggt cccggatgct gctgcccacc ccgcgggtga
     1981 cccgccgggc cgcggagatc gcccgcgcga acggctgcga ccgggtctgg ttcggtgccg
     2041 ccgccccgct cgccgcgatg gcacccggcc tgcggcgtca cgccccgggg atcgggcgga
     2101 cggtcgccac cacgcacggc cacgagatct ggtgggcgcg cacccccggc gcccgccggc
     2161 tgttgcggcg gatcggcgac aacgtggacg tggtcaccta cctgggcgag tacacccgga
     2221 ccaggatcgc cccggcgctc ggtccgcggg cccggctgga gcggctcgta cccggcgtcg
     2281 acgccgacct gttccgcccg gccggcgacg gtgcgcgcgc cgacgggccg gtggtcctct
     2341 gcgtcgcccg gctggtcccg cgcaagggcc aggacgtcct gatccgcgca ctcccgctga
     2401 tccggcgggc cgcgcccggc accgtcctgg tgctggtcgg acgcggcccg gacgagcggc
     2461 ggctgcgcgc gctggcccgg cggcacaccg aacccgggtc ggtggtcttc gccggcggcc
     2521 tggagcacgc cgcgacggcg gcccactacg cggcggcgga cgtcttcgcc atgccctgcc
     2581 gcacccggcg ggccgggctg gagaccgagg ggctcgggat cgtcttcctg gaggccgcgg
     2641 ccgccgggct gcccgtggtc gcgggccgct cgggcggcgc acccgacgcg gtgctcgacg
     2701 gggtcaccgg cacggtcgtc gacggccgca gccccgccgc ggtcgccgcg gcggtcgggc
     2761 gtctgctgcg ggcaccggcc accgagcggg cccggacggg ggcggccgga cggcgctggg
     2821 tgcagcagga gtggtcctgg gagacgtcgg cacgccggct tgccgggctg ctggacccgg
     2881 aacgcgcgga cgcgcaccag ccggatgcgg cccaccggga tgcggaccag cgggacgcgg
     2941 aacgtcctgc accggaccgc gcgtcctccg acgcgaccta ctcgccgcgc aggtgagcca
     3001 gcacggccag cacccgccgg ttgcccacgg ccgggtcgag gtccagcttc atgaagatgt
     3061 tgccgcagtg cttgaccacc gaggcctccg tgatgctcag ccgcccgccg atggcctggt
     3121 tgttcagccc ctccgccatc agcccgagca cctcccgctc gcgcggggtc agccgggcca
     3181 acggccgctc cgtcgactgc tgccggagca gcacccggac cacgtccggg tcgatcacgg
     3241 tctgcccggc ggccacccgc cgcaacgcgt ccaggaagtc ggcgacctcg ccgacccggt
     3301 ccttgagcag gtagccgagc ccggccggct gcgcaccggc cgcgccgagc agccgggtcg
     3361 cgtacggggt ggccacgtac tgggagagca ccaggacggg cagccccggg tgccggtcgc
     3421 gcagttcgag ggcggcgcgc aggccctcgt cgtggaagtc gggcggcatc cggacatcgg
     3481 tgacgacgac gtccggccgg tccgcgtcca ccgcggcggc cagcgccctc gcgtcgccga
     3541 cggcggcgac cacccggtgc ccgccgcggg tgagcagttc gaccagcccg gcccggagca
     3601 gcacggcgtc ctcggcgatg actatccgga gcacggcacc tccacgcgca gcctggtcgg
     3661 cccgccgatc ggactggtca ccatcagcct tcctctcagg atcgccaccc ggtcggccag
     3721 cccctgcagc ccggccccgg ccgccggatc ggccccgccg cggccgtcgt ccgtcacctg
     3781 gaccaccaac cggccgccct cgacccggcc gtggacggtg atcgcggcgg ccccgctgtg
     3841 cttggcggcg ttggtgagcg cctcggtgac ggtgaagtac gccgtcgtct cgaccggacc
     3901 gggcagcctc gccggcaggt cgatgtcgac cgcgaccggg atcgggtggc gcagcgcgac
     3961 ctcggtgacg gcggcggcca gcccgtggtc ggtgagcacc tgcgggtgga tgccccggac
     4021 caggccgcgc agctgctcca gcgcctgccg ggcctcgtcg cgcgcccgct cgaccagcgc
     4081 ggccgcccgg ccgtcaccgc cgtcaccccc gctgctcccg cccagctcgt acgcggccag
     4141 gccgagggtc atgctgagcg cgacgagctg ctgctgggcg ccgtcgtgca ggtcgcgttc
     4201 gatgcggcgg cgctcggcct cgaaggcgtc gacgaggcgg gcccgggagc gggtcagttc
     4261 gaggacctgc cggccggggt cctcgtcccg ggggccgagc aggaaccgga ccagccggac
     4321 ccggccgacg gtcagcaacg tgcccgcgta ggcgcagagc agcagcccgg ccaggccgac
     4381 ggcggttgcg ggcagggcct ccaccgggcc cgggatcgcc tgtccgggga tcagcatcac
     4441 cgtctcgggg gccagcgccc agaccacgac cggggcgcag accagcgtcg cggagaagac
     4501 cagcagggcg gtgaggccga ggtccgcggc ggccagcggc agcgcgaaca aggcggtgta
     4561 gccgagctcg cgccaggtgg cccgctcgcg cagccgggtg cggaggcggg cccggcggcc
     4621 ggccccgggc agcgggcggt gcggatcggg cacgggcacc ggctcgacca gccgcagccg
     4681 gcggcgttcc agggccccga ccggcaggcc gctgacggcg acggccggca ggaccagcag
     4741 gccgacgccg accacggaca gcgcgaggcc cgccgccaac agcacggcca ggacgacgag
     4801 cagcaacagg ccgagcaccg ctccgctgag cacgtgcgcc cagcagcgcc agggggtgga
     4861 cgaccggagg aagcgcagcg gcctcgcgcg cagggctgcc aggacagcga cgggttgctg
     4921 tccctcgtcc gcccgcttcc cacccatccg gccagcctaa ccgaccgtct gacggccctt
     4981 cggcgcagcg gtcggggcgg tcgatgcggg cgatccgggc gacgtggcca tcacggcagg
     5041 cacggcaggc acggcaggcg cagccgtcgc ggctgccggg tcaggcgcgg ccggctgccg
     5101 ggtcagagcg acggcgacga tcacggccag gccgcccagg agggcgttcc agccgacggg
     5161 ttcggcgagc aggagggcgc cgaggccggt cgaccagagc ggggtgacgt aggtgacggc
     5221 ggcggccacg accgtgccgg cggtgcggac cagggtgagg ttgaggatgt aggcgacgcc
     5281 ggtgccgagc gcgccgaggg ccaggagggc ggcggccgga ccggcgcccg gccagcgcgg
     5341 ggcgcccgcg gcgaacgggg caaccagggc cgactcggcg gcggcgcagg cgatctgcac
     5401 ggcggagagg ccggtggccg agtgcggacg gccggagagg tggcggcgca ggtaggcgaa
     5461 gccggcgccg tagcagcagg tcgcggccag gcaggcgagg ccgccggtca ccccgcccgg
     5521 gcctgggccg cgccacaccc cgaggagggt cagcaccccg gcgaacccca ggccgagccc
     5581 ggcgaggcgg cgcgggcccg gccgccgctc cccgggcacc acgaggaccg cgaagaccag
     5641 cgtgaacagc ggggtggtgg cgttcaccac cccggccagc accgagctga cccgggtctc
     5701 gccgtaggag aagagggcga acggcacggc gttgagcagc agtgcggcca ccgccgagtg
     5761 gccccaggtg gcgaggtcgc gcggggcggg ctcgcggcgc agcgcgagga tcgcccagag
     5821 cgccgccgcc ccgaggacgc agcgccagca cgccacccac agcgggggca cccccacgtc
     5881 gacggccacc ttgatgagcg cgaagctcgc gccccagatc gccgacagtg ccacgaaccc
     5941 cggccaccag cgccgcaccc cgaccactcg tcctctcccg ccttcgccca cgcggacctc
     6001 cgcacgaacg ggccttcgcg cccgtacgcc ctcgtgccgt acgccgtcgc gcccgtacgc
     6061 cctcgtgccc tgcaaccgcg tgccgagcgc cctcgcgccc gtggacagag ggtggcccga
     6121 ggccggagca tgagtccaac aagtggtgat gccgcacgga tgaggaagtc tcatggcctc
     6181 ggaggtcaat ctcgcccagc tcagggcgct gatcgcggtc gccgacgcgg gcgggttcgg
     6241 cgcggccgcg tcggagctcg gcatcagcca gtccgccgtc tcgcacgcgg tcgccgcgtt
     6301 ggagcgcacc ctcggcgcgc ccgtcctgca ccgcaccgcc ccggcccgcc cgaccccgct
     6361 gggcgagcag atcctcccgc acgcccgcac ggcggtcgcc tccgcggcgg ccgtgcgcac
     6421 catcgccacc cggcactcgg gcggcctcac cggcaccgtc cggctggccg cgccgaccac
     6481 cgtctgccag ggcctgctgc ccgggctcct gcgggactgg cgggcggcgc acccccgcct
     6541 caccgtcagt gtcttcgagg gcgaggacga cgagctggcc gtctggttgg aggcgggcac
     6601 ggtggacgcc gccgtactgg tggacgccga cccggtgccg cccgggtcgg tggcgctcgg
     6661 cgcggactcg atgcacgcgc tgctgcgccg tgaccacccg ctcgccgggg agccggccgt
     6721 cgacgtggcc gacctggagg acgacgactt cctgctctcc gagggcggct gtgagcgcca
     6781 catccgcgag gcctaccgcc gggccggcgt ccggttcgcg ccccggcacc ggatccgcga
     6841 cctcaacacc ctgatcggca tggtgcacgc cggtgtcggg gtctcggtga tgccggcgct
     6901 ggcgcagccg atgttgccgg ccgactgcgt cctcgtcccg atccgccccg ccgtccaccg
     6961 gtccctgacg ctcaccggac cgggcggccg cccctggtcc cccgcggtga acgggctgct
     7021 ggcggccgtc cgctcggcac ggagctgagc cacccgcccg ccgggcggcc gagcgcaccg
     7081 cccttccccg cgaagtcgcc ttgaccgttt cggggttgac gccctctcag gacaggtcta
     7141 taccagtgga ggtcttcggc gacgcggcgt cgccgtcggc ctccccgggg cccgacgcgc
     7201 ctcccccact gttggcgcgg gcgggcctcc cctgccgttt ccctgagagg tctcccatgg
     7261 aacgtgctct tcccccacag cagttggcac aacagaccgg acggcaaccc ggggcgcagc
     7321 accggcgcag gcaccggcgg gccgtggtcg ccgcggccgg cgtgctcggg ctggtggccg
     7381 gcgggctcgc ggcgctcgcc gggagcgggt cggcggtggc cgcggtcgac gcggcgtcgg
     7441 ccgccaccgg gctcggcagc aactggtacg cctcggcgcc ctacctgatg cccgaggaca
     7501 acagcccgcc ggacgcggcg gcagtgatgg acgcgaccgg gcagaaggcg ttccagctgg
     7561 ccttcatcct ggacaagggc gggtgctcgc cggcctgggg cggcacctcc tcgatcgaca
     7621 cggacaccgc catgccggcg gtgatccaga ccatccgggc caagggcggc gacgtctcgg
     7681 tctcggtcgg cggctacggc ggcaccaagc tgggccagac ctgcggaacc ccggaggcga
     7741 ccgcggccgg ctaccagaag gtggtcacca agtacgggct gaaggcgatc gacttcgacc
     7801 tggaggagcc ggagtacgag aacacggccg cgatccgcaa cgagatcggg gcggcccgga
     7861 tcctccagcg ggacaacccc gggctgtacg tctcgatcac cacggccggg accaacgccg
     7921 gcaccgggtg gttcgggcag cagatgctca acgaggccaa gtcgcagggc ttcacgccgg
     7981 acaactactc gatcatgccg ttcgacggcg ggttcaacgg cgcggcggca cagaccaacg
     8041 ccctggtgag gttcaaccag atcctgcaga ccaccttcgg ctggaccgag gccaacgcct
     8101 atgcgcacga gggcgtttcg ctgatgaacg gccggaccga cgccgcggag tacttccggc
     8161 aggcggactt ccaggccgtg ctggacttcg cgctcgcgca caagctggcc cggtacacct
     8221 actggtcggt caaccgggac cggcagtgcc cggggacggt cgacccgggg ctctccgggt
     8281 cgtgctccag cgtggcgcag aacgactggg acttcaccaa gttcaccgtg cggttcgccg
     8341 gggccacccc gcccaccact cccccgacca cgccgccgcc caccagctcc tcgcccgggg
     8401 cctgcaccga tccggcgtgg agcgccgcca ccacgtacac cggcggcgcc aaggtgtcgt
     8461 acggcggcca caagtaccac gccaagtggt ggacgctgaa cgagaacccg tccgccggcg
     8521 ggcagtgggg cgtctggtcc gacgacggcc cctgctgagc ccgggtgggc ccgcccgcca
     8581 cggccgacgg gccggcgggc gggcccaccg ctgcactcca ccaccgcgcg ggccaccacc
     8641 accacgcggg ccacaaccac cgggcggacc accccagccg gaccgggcca cggccgcaca
     8701 acgcccgaag gaggtgttgc cgtagctggc cccgctcgtt attcctgtta tgagctcaga
     8761 cttccgggca agcggcagcg ccctcgacga aacgattctg cacgatgcgg tcctgcgcga
     8821 atccccgatc ttcgcccggc tcgccctgct ctggctcgac gccggacgga tggtgcccgg
     8881 ccggcccgac caggagtggc gccacctgac cgaacccccg cagctcttcc gcctcggccg
     8941 caccgccgtc gccctgcacc cgggggagga cgcatgacct gcccggagac cccgcgcatc
     9001 ccctcccagc gcaggcccgc cgggtcctgc gccgtgccgc tggaactccg ggccgtcgtc
     9061 tgccccggca tcaccgtctc ggtcgccgcc tgcctgcgct acgaccccgc ggagccgtac
     9121 gcggtgtacc tggacaacca caccgacctg gacgagccga tcacctggat gttcgcccgc
     9181 gacctgctgg cggcgggcat ggacgcctgg gccggcacgg gcgacgtctc cgtccacccg
     9241 ggcacgggcg ccacctcgca gaccctcttc atcgcactgg gtggcgagaa cggcacggtc
     9301 gtcctccggg cggaggccgc cccggtcaag gccttcctca ccgccaccga gcggatcgtg
     9361 cccttcggcg cggagccccg gcacctcgac ctggacggac tcctccaccg gctcctggag
     9421 gagcgacccc cggagccgga ccggtgaccg cccgcacccg gccgccggcc gccgccccgg
     9481 aggccgcggg ggcctgccgg gtccggcccg ccgaccggcc ggggctgctc ccgctcccgc
     9541 ccggggcggc tccccgggcg cgcccgctcg cggcggcggc cacgtccgcg ccggcctccg
     9601 tcatcgtccg ccatcggccc ggccctgaca gcagcgggcg gtcgacgacg gaaacgggca
     9661 caccattcct ccacggatgt gctcactccg tgaagttgac gcgtcctgac cccttgtcag
     9721 accaatcatt cctacctacc ttcgtggatc aggactccgg ccccatcggg cccggaggtc
     9781 cgcggcggcc gcaacccgcg ccgccgcagg gcgcacgaca agacctggag gcgtcacatg
     9841 cccacagccg tgatcaacga gatccgcgac gcgggaccgc tggtggtcga cgacgagttc
     9901 atcctgttcg aggacgacga ccgcagcgac cacgacgcca ccgcgtgtct cgccgacccg
     9961 tgggtgaccg ccaccacccg cttcgcctgc gacctctgac gtgaccgagt ccatcgccgg
    10021 ccgaagcgga tggtccgatg acacctggtc gtacctgaac gatccgcgga tgccggcgat
    10081 ggaccacggt tggaagctgc acgtctcggc ccggcccggc gacctggagg ccgtgaccgg
    10141 cctcgtcctg ccggtgctgt cgcgtcacgt ctgccacgcg aagtgggccc ggagcccgga
    10201 gaccctgcgc gagatcaact ccggcgtgtc gagcgcaggt gccgtcggga aggcgatcac
    10261 ggtctacccg gcacccggcg tcctcgtcgg gctcgccgac gaactcgtcg ccgtactgcg
    10321 cggccgggag ggtccgcaga tcgtcagcga ccggcgggtc gatccggccg cccccgtcta
    10381 ctaccgctac gggcccttca cgggcgacta ccggaccggc cggagcgggc ggctggagtc
    10441 ggtcatggtg ggcccggacg gccgggcgtt cgacggcctg gccgacggtt cgtaccgctg
    10501 cccgccgtgg gccgaggatc cgttcgagaa ccggcccggg cacgacgccg ggccgcgctc
    10561 ctccgccggg ttcggcggtg gacgctaccg ggtcaccggc ggcatcgtgc gcaagccgca
    10621 gggcaacgtc taccgcgcgg tcgacctggc caccgggcag ccggtggtcg tcaagcaggc
    10681 acgggccttc gtggccgagg acgagtccgg tgcggacacc cgcgaccggc tgcgcaacga
    10741 gcgcacggtc ctggccgcgc tcgacgccgt ccccggcgtg ccccgcgcgc tcgactactt
    10801 ccggcaccgc tcggacgagt acctggtgat gaccagctgc ggcggccggg acctgcggcg
    10861 ggaggtccag gagaacggcc cgtaccggcc cgatccggcc cggccgtcgc gcacggtgcc
    10921 cgacctggcc gcccagctcc tccgcgtcct ggacggcatc cacctccggg gcgtggtcgt
    10981 ccgcgatctc aagcccggca acgtcgtgct cgacgccacg ggccggtgcc gggtgatcga
    11041 cttcgggatc agtgcgctgg acggcgtcgg cccggacggc tcgacccccg gctacagcgg
    11101 cccggtccgc cgcgggaccg gcggcacggc cgagcccgcc gacgactact acgccctggg
    11161 cgcgacgctc tgcttcgccg ccaccgggat ggagccggtg atcgtcgacg ccgacgacgc
    11221 cgtcaaccgg gaccgcaccc tcgactgcct ggcctgggcg ctgcccggcg acgaccaccg
    11281 gtggatccgg gcggggatcg ccgggctgat gagcttcgat ccggccgtgc ggaccgccgg
    11341 cgccgaccgg ctccgggccg gcgcgcccgt cgcggcgtcc ggggtgcccg cggcggcggc
    11401 gtccggggtg tcccgaccgt cccggggccc cggacggctc cgcttcgacg acggcctggc
    11461 cgaggaggtc gtcgagcaca cggccgcgtt ctgcgtcgac gaggcccgca ggatcgcgga
    11521 ccccgtactc gccgcccgcg cgaacatccc gacgccggtg gacgtctacg gcggcagctc
    11581 ggggctcggc ctggagctgc tgcaccacct ccaccggccc ggggtgcggg aaaccgtgga
    11641 cgccctggcg cagtggacga ccggccagtc caggaacctg tcgccgggct tctactcggg
    11701 ccgtaccggc gtcgggctct tcctcgccga ggcgggggcg ggacccggag gccacgcgga
    11761 ccatccggac cacccggacg gcccggacct tcccgcccgc ggaccggacg gcggaccacc
    11821 ggaggcggac ctgatcgagg gcgtcgccgg aatcggcatc ggccgcctgc tcctcgcccg
    11881 gcacgccttc gccgacggtg acagccggct cgccgaccgg cacctcgccg tcgccgccgc
    11941 gtgcgaccgg atgctcgcat ccggcagggc ccggctgacg ccggcgggcg ccgacgggat
    12001 cggcagcgcc gccctgcgcg agggattcgc gcacggcgag gcgggtgtcg cgtacttcct
    12061 ggtcgagtac gcgggcgcga ccggcgatcc ggccgccctc caccgggccc ggcgggcctg
    12121 cgcggacctc gccgccgtca cgccgggcat catcgccgcg gcggccggcc cgggggcgac
    12181 gcgacgctac ggctcgtggt gccggggcct ggccgggatc gggacggtgc tcgtccgggc
    12241 cgccgaccgc ctcggcgaac ccgggcacct cgtcctcgcc cagcgggccg cgcgcacctg
    12301 cgccgcgctg gcgccgcgca tgcccctggt caaccagtgc tgcggcctgg ccggcgtggg
    12361 cgacctgatg gtggacgtcg cccgggcgtc gggatccgag gagttctgga acgccgccga
    12421 gaccgtcgcc gcgctcatcc tgagccgcag cggcggcacc ccgtcccgtc cggtgttccc
    12481 ggacgccgga ctggcccggt cgagcgccac ctgggccggc ggctccgccg gcgtactcgc
    12541 cttcttccgg cgactgcacg accgcggcgg acagcggctc ggcctcgtcg actgaccgcc
    12601 tccgggcgcc gcaatgccgc cgccggcgcc cccggggcac gcggacgagg cggcgcgggt
    12661 tccccggtca tccgatattg cggggcggca acctgcccat gtgccgcaga ctcggaccga
    12721 gcacttttcc agaccggagg atggcattca tggttgaccg gcccttgacg ctgatggcgg
    12781 tgcacgccca ccccgatgac gaagccaccg gaacaggggg tgtcctcgcg cggtacgccg
    12841 cggagggcgt tcgcacggtc ctcgtcacct gtaccgacgg cgcctgcggt gacggacccg
    12901 ggggcgtcaa gccgggcgag cccgggcacg atccggcggc cgtcgccgcc atgcgtcgtc
    12961 aggaactcaa ggcgagctgc gaggtgctga acgtcggcca cctggagctg ttggagtacg
    13021 ccgactccgg gatgatgggc tggccggcca acgacgcccc cgggtccttc tggcggaccc
    13081 ccgtggagga gggcgccgcc cgtctcgccg aactcatgcg gcactaccgg cccgacgtgg
    13141 tcgtgaccta cgacgagaac gggttctacg gccaccccga ccacatccag gcgaaccgca
    13201 tcacgatggc ggcgctggcg atgaccggga tgtcgccgaa ggtgtactgg acgacggcgc
    13261 cgcgctcgat gatgcaacgg ttcggggagg tcatgcgcga gttcggcgcg gactgggagg
    13321 agccggatcc ggcggaggcc gccgcgatgc ccgagatcgg actccccgac gaggagatca
    13381 cgacctgggt ggacaccacc gagttcggcg gccagaagtt cgatgcgctg gccgcgcacg
    13441 ccagccaggg ggagaacatc ttcttcctga agatgggcaa ggagaggttc accgagctca
    13501 tgggcgtgga gaccttcgtg cgcgtcgcgg accccaccgg cgtggccgta cccgagaacg
    13561 acctcttcgc cgggctgcgc tgatcccggc acggcccggg ccgccgttcg cgggcggccc
    13621 gggccgcgga cggcggctgt gcagacggtc caggtggtcg gggtcagcgg acgtcagcgg
    13681 acctagcagg aggtcaacgg ccctcagcgg acctcagcgg gggatcaacg gccctggagg
    13741 gacctgacgt tgtcgccgaa ggtccagccc ttcgagccgt cccagttggc cgaccacgtc
    13801 atgagcccct tcagcgaacc accgaaggcg ttccacgact ggccgaccag gctcggcgcc
    13861 atgtagccgc cgcccgcacc gggctgggcc ggcaggccgg gcacctgctt gtcgtagggc
    13921 accttgatcg tggtgccctg gatggtgagg ccgttgttca ggcaggtggt ctgcgcggtg
    13981 aagccctgca cggtaccggc ctggtaggag tcgccggagc agccgtacat gctgccgttg
    14041 tagtactgca tgttcagcca ccacagctgc ccgttgtcgg cgtacttctt gatgatcggc
    14101 aggtaggcgc cccagatcga cccgtaggtg acgcttccgc cggtgacgta ggcggtctcg
    14161 ggggccatgg tgaggccgaa gccggccggc atccgggcga ggacgccgtc gatgatgcgg
    14221 atcaggttgg cctgggaggc ggacagcgtg ttgatgttgc cgctcccgga caggccggtc
    14281 tcgatgtcga tgtcgatgcc gtcgaagttg tacttcttga ggatcgggac gacggtcgcc
    14341 acgaacttgt cggcgacggt gccggagctc aggtcgatgc ccgcggcggc gccgccgatc
    14401 gacatcagga gcgtcgcccc ggccgccttg gcctggcaca tctcggcggg cgtcgagacc
    14461 ttgacgccgg cgtccatgcc gtcctgccac aggacggtgc cgtccgagag gatcaccggg
    14521 aaggcggcgt tgatgacgtt gtagccgtgc gcggcgatcc ggctgtccgt gatggggacc
    14581 cagcccaggc cggggtggac gccattcgcg gcgccgtccc agttctccca gtacccctgc
    14641 aggaccttgc ccggcggctt gggcttcgtg gggcaggtgt cccccggcgg cgtcgtggtc
    14701 ggcgtcgtgg tcgtgggcgg ggcggtggtc ggcggcgtgg tcgtgggcgg ggcggtggtg
    14761 ggcgtggggg tgctgccgcc ggggcccgtg agcgacacgt cgtccgcgta gtacgcgggc
    14821 tgcccgtacc agccgtgcag gtagacggtc accgaggtgg tgctcggccc ggtggtgaag
    14881 ccgacgctga gccggccgta cgacgggctg ctcggcgtcc aggtggacgg ggcactggtg
    14941 atgcccgagc cggtggcgcc caggtagacg tagctgccct ggacgtaggc gctcagcgtg
    15001 tactgggagt cgggctgcac gctgatggtc tgggcgcact gggcgttgtc ctggccggtc
    15061 ggcgtggccc tgagcgcgga ggcgccggag tggaccgggc tgctcaccgc cgcgccggag
    15121 ccaccggagc aggtccagtc ggagagcccg ttctcgaacc cggggttggc caccaggttg
    15181 gtggtggcgg ccccggccgt gacggagccg gccacggcga tgccggcacc gatgacggca
    15241 ccgatgacgg cggtggcgct caccccggcg agggatcgct tcaggacggt cggtccgttc
    15301 ttggcggggc tggtccggtt cacctgcggc gcgcgctcca cggtcgcccg gtgcgggcgg
    15361 ggaacccggg gcggctcgct cccggtccgg ccgccttcga ggcgggcggg atccggacaa
    15421 gggcggtgat ggcccgacag gcgcggagta cgcgatctcc gacggaacat gctgtgctcc
    15481 cttcccgccg ggcgccatgg acatgaccgg cgtgggcgtg gcgcccggct ctgggtgagg
    15541 tgggggacat gtggggctgt gccggaccgg atcgtaggag gggcggcagg gcccgtcaat
    15601 aggtctggac caattgcggg attgcggctc attccggcaa ggacggtccg cgcaagttcc
    15661 gcgtacggga aggccgctga ctcctcacca ccggcgcggc ccccgtggca ccgggctccg
    15721 ccgtcccgac cccttcgtgg cgcggggccg ggacgacgag gccgccccgg ccttcgcacc
    15781 ggacgggcgg ccttcgcccc ggccttcgcg tcagacggcc ggcttccgga cgggggccgg
    15841 cccggcggtg aggagcgccg tgatctcgtc ggcgaggtgc gggccgagct cgccccagcc
    15901 gtccttgtag ccgtagacgc cggccagggt acgggcctcg tagtcgccgt tcatgatctc
    15961 gatgtcgtcg ggcgtgatga gtgccgggtg ggcgacgccg acggccgccg agaccttcat
    16021 cagctccctg cgcagggtgc gcaggtacgc agcagcccgg tcggccttcg aggccgggtc
    16081 gatgccgcgg gccagccacg ggttctgggt cgcgatgccg gtggggcact tgtcggtgtg
    16141 gcacttctgc gcctggatgc agccgatcga cagcatcgcc tcacgggcca cgttgatcat
    16201 gtcgaccccg agggcgaagg cgaccgcggc gttctcgggc aggccgagct tgccggagcc
    16261 gatgaaggtc aggtcgtcgg tcagccccag ctcggcgaag gtgccgtaga cccgggagaa
    16321 gcccatccgg aacggcagcg acaccgagtc ggcgaagatc cgcggcgccg ccccggtgcc
    16381 gccctcgccg ccgtcgaccg tcacgaagtc gaccccgcgg tcaccccgcg ccatcagcgc
    16441 ggccagctcc tgccagaagc ccatctcccc caccgcgctc ttgaccccga ccggcaggcc
    16501 ggtctcggtg gcgatcagct cgacgaagtc gagcagcgag tcgacgtcgc tgaacgcggt
    16561 gtgccgcgac ggggaggcac agtcctcgcc gacggggatg ccgcggatcc cggcgatctc
    16621 cggggtcacc ttcgcacccg gcagcatccc gcccaacccc ggcttggcgc cctgggagag
    16681 cttgatctct atcgccttga ccggagcgcc ggcgaccacg tccttgagct tgtcgaggtt
    16741 gaacgtgccg tcctcgttgc ggcagccgaa gtacgccgtg ccgagctgaa ggacgaggtc
    16801 gccgccgttg cggtggtgcg gcgagaggcc gccctcaccc gtgttgtgca tcgtgcccgc
    16861 cagcgccgcc cccttgttga gcgccgtgat ggccgccccg gagagcgacc cgaagctcat
    16921 cgccgagatg ttcaccacgc tcgccggccg gaacgccttg gcgcgcccgc gcggcccgcc
    16981 cagcaccttg gccgagggca gcgaggcctg cgggtcgtgc gcgtcgggca ggtggccggc
    17041 gaacgtccgc tgcttcaggt aggcgtggcc ctgcacgtgc tcgacgtcga cctcggttcc
    17101 gaacccgaag tagttgttct cctccttcgc cgacgcgtag atccacgtgc gctggtcacg
    17161 gctgaacggg cgctcctcct cgttggaggt cacgatgtac tgccgcagct ccggcccgat
    17221 cgtctccagc aggtaccggg cgtgcccgat caccgggaag ttccggagca gcgcgtgccg
    17281 cttctggacg aggtcacggg ctgccaggag cgccaccgct gttgcggcgg ccgcgccgat
    17341 cttccgggct tgcatggacg ttcctcctcg atgcacaacc tcatcgtcgt gcggtgaagt
    17401 catcgtgtcg tgtggggcgt tggacggcac gggcacatgg ctgggccggc ggcggcgtcc
    17461 gtcggagaat gccaaacgat ggtaagagtc cacaccgacg ggcatgcggc caggggtcgg
    17521 tccggtccgg agccggcttc gcgacggcgg gtgacgatgg ggcgcccggc cggtgcgcgg
    17581 cgacgaggcc cccggcggtc ggcgggtggt caccgtcgtg acggccgccg acggcaccgg
    17641 gggtcggcca ggcgccgtag gtgagggtga cccggcccgc caggtcgtgc aggtagagca
    17701 ggttgagctc cgggaagggg tgcctgtccg agatccgggc gtatcccgga ttccccatgc
    17761 cgcggctgcc caggacgcgg ctgcccagga cgcgggcgcc gtgggcgccg cccgaccggg
    17821 ccggcgtccc cactcggggc gctggtggcg aaccgaagca ggaacggttc gccgtctcgg
    17881 ccgcagggcg gccacgggag cgcctccggc gggccgctca gagccggacg gtgaaccaga
    17941 tggtcttgcc gctgccgctg gggcggaccc cccagccgtc ggccagggcg tcgacgatga
    18001 tgagcccccg gccggactcc tcctcgctgg tggcgaggcg ggggtggggc agctgggagc
    18061 ttcggtcgcc gatctcgacg gtgagctcgg tgctggtgcg gcgcagcagc aggtcgatag
    18121 gcccccggcc gtgctggacg gagttggtga ggatctcgga cagcaacagg caggcgtcgt
    18181 cggttcgctc ggcgcagccc caggcggtga gcgtcttggt gaggaaggcg cgggcctcgc
    18241 cgacggagga gggaacggtg ggcaggtcgg tggtggcggt ggccagcggg gcggcgggaa
    18301 gctgcagcag gaggagggtg acgtcgtcgt tgtggccgtc gctgtcgggc agcacggcgg
    18361 agaggacgtg gtcggcgacg gcctccaacc cgccgtcgcc ggtgaaggcg cggtcgacgg
    18421 tcgcggccaa ctcggtgatc tgggcctcga tgtcgccgcc gggggtctcg accaggccgt
    18481 cggtgtagag cagcagggtg gcgccgggcg gtacggccag acaggcctgc tggtggggaa
    18541 tgccgccgac gccgagcggg gcgctcaccg gggccggcag cgcccggatg gtctcgccgg
    18601 ggacggcgag gaggacgggc aggtgcccgg ccgagcagat cgtgacctcg ccggtgtccg
    18661 gggcgatgac gaggtagcag caggtgacca gctggtcggg cagctcaagg tcggtgacgg
    18721 ccgcgtccag ggcctgcatc agccggcggg gttccatgcc ggtcttggcc agtgcgtggg
    18781 cggcggagcg cagctgcccc atgacggcgg ccgcctccag cccgcggccc atgacgtctc
    18841 cgatcaggac gccgacgcgg ccggcgccca gggggatgag gtcgaaccag tcgccgccga
    18901 ccccggcgcc ctgggtggcg ggcaggtagc ggctggcggt ggccagtccc gggatggcgg
    18961 gtggggtgcc catcaggctg cgctgcaggg tgagggcgat gtgccgttgc tgttcgtaga
    19021 gggcggtgag ttccgcctcc gctcgttttc ggtcgctgat gtcgcggacg atggcgcagg
    19081 caccggtcac cgtgccgtcg gcggtccggg tgggccacag cgtcacgtcc acgtcgatca
    19141 gcctgccggt gcgggtgacc cgcaaagtct cgaagtgctc gaccttctcg ccgtctccca
    19201 gtcgcttcag cagcgccgtg atctcctccc ggtgctcggg cggggccagc atggccacat
    19261 ggcggccgag cgcctcggcg gccgtgtagc cgtagagcga gtgggcggcg gcgttccagt
    19321 aggtgatgcg gccgtcgagg gtcttggcga ggatggcgtc ctgggaggac tcgaccagcg
    19381 cggcgagctc gttgatgcgg gcttcggcgg ccttgcggtc gctgacgtcg cggacggcgg
    19441 cggagaagag cagaccgtcc gcggtctcca gcgggctgag actgatctcg accgggaact
    19501 ccgtgccgtc cttgcgcaac ccgtgcagct ccagccccgc ccccatcgga cgcacctgcc
    19561 ggttcgccgc gtactcgtcg cggtgccggt gatgctgacc ccggaaccgc atcggcacca
    19621 gcaactccac cggacgcccc agcagttcct cacgcggata cccgaacaac gcctccgtct
    19681 gcgcgttgac cagcgtgatc acccccgcat cgtccgcgat caccatcgcg tccggcgccg
    19741 cctccaacaa cgcccggaag cgggcttcgg cggccttgcg gtcgctgacg tcgcgcacgg
    19801 cggcggagaa gagcagaccg tccgcggtct ccagcgggct gagactgatc tcgaccggga
    19861 actccgtgcc gtccttgcgc aacccgtgca gctccagccc cgcccccatc ggacgcacct
    19921 gccggttcgc cgcgtactcg tcgcggtgcc ggtgatgctg accccggaac cgcatcggca
    19981 ccagcaactc caccggacgc cccagcagtt cctcacgcgg atacccgaac aacgcctccg
    20041 tctgcgcgtt gaccagcgtg atcacccccg catcgtccgc gatcaccatc gcgtccggcg
    20101 ccgcctccaa caacgcccgg aagcgttcct ccatcgtccc cgcatccgcc gtgacacccc
    20161 ggcagcccgt cccctggccg gcagtcgtgt ccttgcccgg tctccggccc acctcgtcgc
    20221 ccacgcccgc tcccttgcct tgccgtaccg gtggtggtgc tccaccccag cgcatcaggg
    20281 ctccgggcgc ctacctatgt ccgcaattgg ccgctgacat ttgaatactc ctaaaggaag
    20341 atcaaaaatg accatatgcc tcgggcttgg actcactcat cgtcgagcgg gccgcccggt
    20401 cggtggcagc ccgacgggag cgcgggttga gggccgtcgc agcacgccga gcggcccggc
    20461 cccgacgaag gccgggcccg ggccgcttcg gccacgctcg acacccgcct cgaccgggac
    20521 gacgccgcgg cgagccccct cagcgctcgg ctcaccggtc cgaggaggcc gacggttcag
    20581 cggtgttcgg gttctcgaag tcgaagcggc agccggcgtc ccgctccgaa cgccggttgc
    20641 cctcggccgg gatgccgccg gagccctcgt ccaggtacga cggtccgggg ccggcctcac
    20701 cgacccgccc ggcatcggca tgaggactcc cccatcgtgg gtggttcggg cgggaattcc
    20761 gtgcgcgtgt cgcccggctc tgacagagcc gcggtcggac acgaggacag gcggatcgaa
    20821 tgcaggcgaa ccgccaaaga ctcgatgacg gtcgaaagtg actgcgcgac cgaaaggtgc
    20881 cggtgatcca tgtcaacccg ggcgcgcggt cccggcatga tcaggctcga tccgtcacac
    20941 ctgtctcccc gggtgggggt gatctgcggc gcaccccgtg aagcgttccg acgcgctgaa
    21001 ggccgctccc tgtcacgcga aattcacgga ccagggtcta ctcgcataga catcggtgag
    21061 gcatcctggt gcgatgccgg cgcccgaagc ccgtccctcg tcacccggga accgcggacg
    21121 gtcgccggac ggatcggtcg gccctcgcgc cggagcaccg ccgcgtcaca gcactgcgta
    21181 cgtccccctc gtccgggccg gttccccggg cccggcgccg gacttcccgt cctcccgccg
    21241 aggtgcggca ggaaggcggg ggtcgagtcg gaggcacacc atcctcacca ccgggagatg
    21301 cagatgaagc cacgcaccgc agccaccgtc gccgccctga ccgtggccgg cctcgccgtc
    21361 tcggcgccca cggccggcgc cagcggcacc aagctgtcgc agtcggcggc cgccggtcag
    21421 ttcagcagcg ccggaatcac gtggagctcc agcgggggct gcaccaccag gtccaactcc
    21481 acctgcacct cgttcgagca gatcaactcg ggcacggtga acgccatcat caccctcaag
    21541 cgggccagtg gctgtgccat caacatcacg ggcgggaccg aggtcggcca cgcctccggc
    21601 acctacagcc actacaacgg ctacaaggtc gacatcgccc gcaactcctg catcgacggc
    21661 tacatccaga acagcttcac ctacatcggc taccggggcg acggctaccc gcagtggaag
    21721 gccgcctcgg gcaacctcta ctgcaacgag ggcaaccact gggacatcct ggtctactga
    21781 cgccgacctc ggatgccggc gccccgaggg gcgccggcac gccggaagcg cgtcagggcg
    21841 gtagcggacg agacaccggc acgcggcggt tcagcggtgt ccgggcactc gtccggtcct
    21901 gcggcgccgg cgaccggagc attggccact gctccggccc ccggcccccg gcccgcgcca
    21961 gccggatcag tacgcgctgt cgtacgtgta gaacttggtg tggtccagca ggtcggccgg
    22021 ggtgacgtcg ttccacggct tcatcgtgtc gttcagggcg accacgttcc tggtgcggcg
    22081 gaccggctgg tagccctggc ccgcatggcg gctctgccag ccggcccaga ggcggtcgat
    22141 catgcagtgg tgcatccaga acaccgggtc gttgggcgac atcccggtgc tcatggtgcc
    22201 gccgacccag acgtgcaccc ggttgtggac gttgacaccc acccagccct ccaggctgtt
    22261 gcggaagccg gcgctggagc tgttgaacgg cgcggcgtcg tacgtggcga tcgccagcac
    22321 ggcgtccacg tcggccctgg tcggcaggtt ctctccggcc cggcccagct gacggatcag
    22381 gtagttgcgg ctgtcgggcc tgacggtgag cgtccagctg ccggagctct gcgcgaacgg
    22441 gccggtggcc acccggccgc cggtgccggc gccgtcaccg ccgaggaagt ccgggcccca
    22501 gagggaggag tccggggtgc ggtcggtggt ccagtcccag tacgggagcg tgacggtggc
    22561 gtcgatcgcc tgcagtgcct gctcgaagcg cagcagaaag ctgcggtgcc agggcaggaa
    22621 ggacggcgag cggtggccgg tgcgctcggt ggtgtcggtg tcgctcatga tgaagtcgtt
    22681 gtgcgtgctg acgaacgcgt cgtacgcacc gcggcgcttg agttccagga ccgcgttgac
    22741 gaacgcgcgc ttctcggcgg gcgtcagggt cgcctggttc ttgcggacag ccatggttct
    22801 tccttgaggg tggtctgtgc gggaggccga agcggtccgg agtcaggcgg cgagcggggc
    22861 caagtcggcg ccgctcaggg cgttgacggc ggcccggacc agcgcgcgcg gcgtggtgaa
    22921 cgtctggtag tggttgatga cgctgatcca ggtgccgtcc gcgttgcgca tcatgtgcag
    22981 ttcgcggccg tcgatcagca ccatgtagcc gctcatcgcg tggtggccgt cgccggacat
    23041 cggcatgccc tggatgcggc ggccgcggaa cacctcgtcg aagctttcgc cgctctccgt
    23101 gtcggcgccg ctggcgggtg ccacggcggg accggtgaga cccaggacga ccgtgcccgc
    23161 ggcgagggcc gacgcgacaa cggcgccttg cagcatccgc cggcgggtga tttcggtggt
    23221 ggtgtcttcg gacatggcag tgccccccag atggaaaacg tgaagaactt tcagtgcccc
    23281 cgtagcatgc ggaccggtcg gcagattcgg cggcgatcgg cccgctcgga atcattccta
    23341 ccagtcgtga gcgaacagtc cggatgcgtg atcgacttga gggccaaaag tgatcatttc
    23401 aagccggtca cgtgaaggat gttgcatctt ttacagaagc cagagcttcg gttcgcagcg
    23461 aatcctgcgc gcgaaaaccg gagatccttc acccgggcgg ccaccacacc gcaaggcctg
    23521 cggccctgac gcaccttttg tgacggtcgc tacacgaaca ggttgacgcg atgccaccag
    23581 gtgatcacgc cctgcctgac cagcggctcc atgactgaca taccccagga gtcccgctgc
    23641 ccgccgtgtt caccccgcac gccacctcag gggctccccg gccttcggga acgagtcgtc
    23701 gtcgaccacc cactcctccg gcgcgagggc ggaggtcatc ccccggacga tccgccgcag
    23761 caccggcgcg tggtcccgcg gcgactggct gacgaaccgc cgcagggccc gcatgttccc
    23821 gtccggcagc cgctcggcga tgggctggat cgacgtgcgc cacccatccg gcatcagtcc
    23881 ttgcgggtgg caatccccct gccggcgccg gtccttgcgc gcccgggacg cgaacacctc
    23941 ggccacgaag gcgccgaggt gttcgcgcgg cttctccacc tcaccgggat ccaccggccg
    24001 cagcgcgcac cgccgcggca accaagatca aatcaacctg acgaagtact accagccgag
    24061 cgcccgcgtg aactgctcgc gacacactca aaccagccac gcggtacaac tacccatcga
    24121 acaaatcgag ttgtcgggca tctgtcgccc gccgccagca gccttaccgg tcggtgccgc
    24181 cgccatccgg catcgccggc aacggtgacc cgaacgacgg cgtccgtcag tacgaagcgc
    24241 tggtggcgca ccgaccgagg tcggtgttgc acacgacgac gtacgaagtg attccggagt
    24301 cctggagctg gagggtgtag tgcttgtcgc cccggacgtt gctgtaggcg ctggaccagc
    24361 ggccgttcga ctgctggagg tttaccgtgc agtagttgcc cgtagtggag atcacgtagc
    24421 cctgcaccca gtcgtgcccg ttgtagtact gaacgttcat gcctccggca cagccgggga
    24481 cattggcggg gtaggtggcg tcggccgacg ccacccccgt gctgagaccc aggctgcctg
    24541 cggcgacggc agtcacggcg gcgaggcgga cggcggtgcg caacccaatc atcgtttccc
    24601 cctgtggagt tggcggctga ttcctgcgac ctatgctgcc atcgaacccc cctgaaggca
    24661 cgtctcccgc acgaatccac acacgcctgg gacgacctgc cgcgcgcggc gtggcggcag
    24721 ccgtggccgg agccctcgcc gacccggcga accgatccgg tgaacccctg cccggacgtg
    24781 cgtcccgtcc aggtggaccg ccgcgctgcc ctgcgagccg gtcaccgcgc gcaccggagt
    24841 ccaggccatg gcccactcgc caacgccgcc tcgaccgacg gcatcctcga acgcctccac
    24901 caggccaccg gtggcctcgc cctgctctac gtcctctcgc cgttcggcgg cgcgaagcgg
    24961 ctctctgcac cgactacgtc atcggcgaca ctcgcgtgcg ccttccgttc cgccactgtc
    25021 agaaagccgt ctcctggcac cgagctcagc acgccgtcat cgtggaaggc gaggtccgtc
    25081 catgtcggac cgggacgccg cctgctcgtc gacgacccgg gcaagtgtcg ccccatcgac
    25141 gggatcctcc tgcccctccg ctgaaccaga ccccggctca gcggtgctcg gggttctcga
    25201 agtcgaagcg gcagccggcg tcccactcgg agcgctggtt gccgtgggcg gggatgccgc
    25261 cggcgtcctt gagcatgcgg gccaggtgga gcaggttcca cgtcatgaag gtggcgttgc
    25321 ggttggtgaa gtcgttctcc gggccgccgg agccggggtc caggtaggac gggccggggc
    25381 ccgcctcacc cacccagccg gcgtcggcct gcggcgggat cacgtacccg aggtgctgga
    25441 ggctgtagag cacgttcatc gcgcagtgct tggcaccgtc ctcgttcccg gtgatcagac
    25501 agccgccgac ccggccgtag taggcgtact ggccctcgga gttgaggatc gacgagcagg
    25561 cgtagagccg ctcgatcacc ttcttcatca cggaggagtt gtccccgagc cagaccgggc
    25621 cggcgaggac gaggacgtcg gcggccatca cctggctgta gaggaccggc cagtcgtccg
    25681 tctcccagcc gtgctcggtc atgtccggcc agacgccggt ggcgatgtcg tggtcgaccg
    25741 cgcggagcac gtcgacctgg acgccctggc gctgcatgat gccggtgctg acgtcgatca
    25801 ggccctgggt gtggctgcgt tcgggtgagc gcttgagcgt gcagttgatc accagggcgc
    25861 gcaggtcgtc gtggcggcgg ggcggggcgg gcggcggagc ggacatcggc ggggcctttc
    25921 gacgggtctt gcgaacctcg caacgggcct tgcgacgggt cacgtcgccg gccttgcggt
    25981 gggtctcgtg gcggagcggt cgcccaccag tccaaccgga ccgccccgcc gccgcccgcc
    26041 gggctgggcc gaccgcctga cggggccgac cgacccactg gacgcgcccg ctggatgcac
    26101 ccgttgggcg gagtccgtcg ggccggaccg tcaggcgccg ccgtccggcc ggtcgaccgg
    26161 gggcagcacc ggggtcacga tcagccgtcc cgccagggcg gcccccgcgg tgacggtggc
    26221 gagggtggcg tcgtagaacg ggcgcaggtt gcgctggtgc cagaggatct gggtggtggc
    26281 ccaggcggcg tcgcgggcac gggcgatgga gaagctggcg acgatgtgct tcagcggttc
    26341 ggtggccccg gtggcggccc tgaggacctg cacctcgaag gaggcccgga cctccgcctc
    26401 gacctgggcc agcagctcgt tcaccttgag gtagtcggcg tgcacgggcg gcgtgtccgg
    26461 cgtggtgcgg cgttcgatgc aggtcgacac cacggcgagc gggaggtcgt ggttgatgtg
    26521 cgcgttcatc ccggcgaagg cgaactggac cggccagacc acccggttgt ccctcgcctc
    26581 gaacagcggc tgccaggacg cgttcaccgg gctgccggcc tcggcggcgt ccacggcgtc
    26641 gaagtagagg ttggcgaaga ccacgtccag gcgctcgatg aacgcctggt cgtggaagta
    26701 gcctgcctgg aggcgttccc ccaccagctc ggtgacccgc aggtacatcc ggttgaagca
    26761 ggcgacgccg tcccgcgggt ccagccggtc cttgatcgcc cgcatccgct cgacgacctc
    26821 ctcgacgctc tgtgcgctcc tggtccgcga ctgggtcatg gttgtcccct tccgaggcgt
    26881 tgggtggtgc cgttcggtcc gactgccacc tatacacacc ggccgccacc gccgcgcccg
    26941 ccaccgtccc ggtcacaccg gccccgttca cccgaaccgc cccctcccgg ctgtcggccg
    27001 ggagggggcg gcaggccttc cggtccgggc ctaccccacc ggccagccgt ccaccgtggt
    27061 gatgctgcgg tggtacggcc cgtccggccc ggtgctgcgg tagtcctcca ccgagccgcc
    27121 ggtgcgcacg gtgctgtccc cgtcgtgccg gtgggcggtc gggcgcaggg tgtggtcgac
    27181 ggtggaccgc ccggtggtcc gggcgccgac agcactggtg tcctcgcggt ggtagccgag
    27241 ttccatggcc gtccgctggt cgctgttgcc ggccgcgtcc cgggtgacct tgtaggtgac
    27301 gtccagcggt tcgccctcgt ggacggtggt ggtgcggtgc gggccggcgc cccaggtggc
    27361 ggtggtccgg gtcaggtccg tgcggttgtg cagggtgagg tcgttgccgc cgtcgcgcag
    27421 ctgctgggcg gagccgaaga cgaggtcgtc gcggacctcg gtggtgacgc gcccgtgcga
    27481 ggtctgcacc cagccgcgcg ccaggtcgtg ccggtccgcc gtcacgttcc agtccccgct
    27541 gccgccgccg tggtccgtga ggaccgtccc gaccgccgcc tccggtgcca cccggtactc
    27601 ggtgagctgc ccggtggtgc gggcggcgcc gcggtccacc tcggcgaaca ggttgacctg
    27661 cccgctccag aggtcgttgg cctgggcctc ggccgcgttg acggcgatgc cgacggagtg
    27721 cgggcggccg tccagcagca ggccgacgta cggggtgagg tcgacccggt acgcgggcag
    27781 gtcgaaggcg aagaccccgg gcgtgggccg ccagagcagc gggtcccatc cgccggtgta
    27841 gatcaccggg tagggccaga ccgcgccggc cgtccgcccg tcgatgctga gccgcagctc
    27901 acggaacggc cccttcccgc acaccccggt ccccgggttg gcgcgggcga actcgtccgg
    27961 cgccgacgcg tacgcgaact cctcgcaggc acccccgccc cgtgcgtaca cctcggcggt
    28021 cagccgctcc aggttctgcg ggaaggtgag ctcgcggccg gccgtcggcg cggcctgggt
    28081 gagcccgaac gccccggtgg tcagcacccg gtcggcggtg cgggccgcgg gccaccgcgc
    28141 ggaggtggtg tagaaggtga ggctggccga gatccggaac acccccgtgt acgtggcgtc
    28201 ggtgacgttg gccaggtcga aggagaacgg ctgcg
//
