LOCUS       NZ_CP026498            21245 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. CB01881 chromosome.
ACCESSION   NZ_CP026498
VERSION     NZ_CP026498.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CB01881
  ORGANISM  Streptomyces sp. CB01881
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     A 3-hydroxy-3-methylglutaryl-CoA synthase gene based probe for the
            discovery of the acyltransferase-less polyketide synthases
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11344947)
  AUTHORS   Liang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2018) Xiangya International Academy of
            Translational Medicine, Tongzipo, Changsha, Hunan 410000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002953255.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 02:39:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,978
            CDSs (total)                      :: 7,904
            Genes (coding)                    :: 7,565
            CDSs (with protein)               :: 7,565
            Genes (RNA)                       :: 74
            rRNAs                             :: 5 (5S)
            complete rRNAs                    :: 5 (5S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 339
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 339
            Pseudo Genes (frameshifted)       :: 124 of 339
            Pseudo Genes (incomplete)         :: 251 of 339
            Pseudo Genes (internal stop)      :: 10 of 339
            Pseudo Genes (multiple problems)  :: 45 of 339
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:44:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2034930
            Orig. end                         :: 2056175
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026498.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21245
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="amglyccycl"
                     /region_number="12"
                     /rules="(DOIS or ValA or salQ or strH or strK1 or strK2 or
                     NeoL or SpcFG or SpcDK_glyc)"
                     /tool="antismash"
     cand_cluster    1..21245
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /kind="single"
                     /product="amglyccycl"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21245
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11245](-)"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11245)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="1"
     misc_feature    61..75
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 17.98"
                     /tool="antismash"
     gene            complement(1389..2021)
                     /locus_tag="C2142_RS08930"
                     /old_locus_tag="C2142_08900"
     CDS             complement(1389..2021)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014627283.1"
                     /locus_tag="C2142_RS08930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08900"
                     /product="response regulator transcription factor"
                     /protein_id="WP_148642295.1"
                     /transl_table=11
                     /translation="MIVDDHPLFREGLKAALQSAEGIAVVAEAERAGAVPDAVARYRPD
                     VVVMDLSLPDGSGLEAARRLAAQPPAPPVLMLTMADDDGSLLAALQAGARGYLVKGAGR
                     EEVLHAVRTVAAGGAVFGADVAGRITALLAGARLREAGQLFPSLTAREAEVLDLVARGL
                     DNRRIARELVVAEKTVRNHVTHIFEKLHVATRAEAVARARDMGLGDT"
     misc_feature    complement(2033..2048)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     misc_feature    2319..2332
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.49"
                     /tool="antismash"
     gene            2499..4742
                     /locus_tag="C2142_RS41475"
                     /old_locus_tag="C2142_08910"
     CDS             2499..4742
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="C2142_RS41475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08910"
                     /product="ATP-binding protein"
                     /protein_id="WP_148641894.1"
                     /transl_table=11
                     /translation="MTSARPRASARRTPRRTPAQRQLTAAAVCTAFCLAVATLWICYVL
                     VHLGEPGVARPRDQLAILLYALPTAGAGMLLHAHRPGSPLGWVMLAYALTSMLPSAAGA
                     SLWVEVSDPGLVGALAVLRSVCDTISQTLFYVLPLWLPSGRLTTRRWWLYIGAVALWEI
                     PDGMSFLGHATSYGHPNPLADSPPAAFFGALSDHLDGLYDPVNYLLVGFSAAVLLFRLL
                     RPAPDGPPDGPAPHPAHRVHVAAMLGAYLLWAGMQDYYNRRFQYEYWLSYSLFAAAGAV
                     WAVAVAYLVIRDGGWRLDRAARSVLTGLLLATGLTTVFVVFAAVLSGWLVPGRGGAALV
                     LIALVFGLGSCLPRPARWAVGLVDRLYYGDRAQPYQVLRTLAGQVRQTVDPERLPAALC
                     ATVAEELRLPGVALSVTTRAGRRRLAAVGRLDGPGQAFALVHHGTVIGELTVAPREGEE
                     RLDPGDIDILRSLADQVSPAVASLQLQEDLQASREQIVAAREEERRWLRRDIHDGLGPA
                     LAGLRLRVDNAASGAASEAAGSAVPRSGPGAGLAETLHGISGDLAMAIKEVRRITDRLG
                     PAPLGEFGLARAVQQLAANFSGAALAVTVSMAPDPLPDLPAAVEVAAYRITAEALNNVL
                     RHARARRAQVCVRVDAETLTLTVQDDGVGVETGETTWAERLPEEAAQSTGGTSGWAGGG
                     VGLRSMADRAAEIGGRCTVAPRAGEHGTRVLAVLPRFPSAGGAAGARRETAGG"
     assembly_gap    4841..4850
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(4868..5095)
                     /locus_tag="C2142_RS08940"
                     /old_locus_tag="C2142_08915"
     CDS             complement(4868..5095)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS08940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_08915"
                     /product="hypothetical protein"
                     /protein_id="WP_148641895.1"
                     /transl_table=11
                     /translation="MATNTARKTLGVASVVVGCAAATFVLKSTVVGATARSCRTPESTA
                     RRTARPVAKNRTRPVAKNRRCKAGETDCKG"
     gene            complement(5264..5557)
                     /locus_tag="C2142_RS08945"
                     /old_locus_tag="C2142_08920"
     CDS             complement(5264..5557)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS08945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_08920"
                     /product="hypothetical protein"
                     /protein_id="WP_148641896.1"
                     /transl_table=11
                     /translation="MNTPGTDTGRGVLPGAAAVVTATVTVTVTGSGIGRATAIAPARAG
                     HAAATGCRADRSAARRTARQGRGGRVVDVTAPYERTTADRLFTSGGPWTGSR"
     gene            complement(5554..6309)
                     /locus_tag="C2142_RS08950"
                     /old_locus_tag="C2142_08925"
     CDS             complement(5554..6309)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012417.4"
                     /locus_tag="C2142_RS08950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08925"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_148641897.1"
                     /transl_table=11
                     /translation="MILVPAAVPRTAPAFRWLIDPRHLPSALGGLSVETLSPGVRVGQR
                     PAPAGESVTVVLSGRVRSAGRVLGPGEGLYHPPGSDCGLAVLPGAPAVVLTVRAGPSAG
                     PRPVPGLSVVPLAAPSRRTGPPEGEDGPAAGGAAGTAVHWLATAETVGARQVAVAAFGF
                     APGGSHELHRHPHADQFFLVLAGGGRHLAATREVAVRPGDLVYVPAGEWHGFRAGPGHP
                     TAAVYGYLGAASPARAGYQVRPAAEEVLR"
     misc_feature    6525..6540
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    6535..6550
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.04"
                     /tool="antismash"
     gene            complement(6536..6946)
                     /locus_tag="C2142_RS08955"
                     /old_locus_tag="C2142_08930"
     CDS             complement(6536..6946)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS08955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_08930"
                     /product="hypothetical protein"
                     /protein_id="WP_148641898.1"
                     /transl_table=11
                     /translation="MIITTASAAAAVILGPHGERIRLRCLARRSMLAGACESFDHLRLS
                     PGAHHVLPGQNETENVLYVLRGSLLVGGSPDEPDHLAVDGDLLLARRGTPLHLDAGPLG
                     AELLCLALAAPRRASATRDALARRRAERRTRP"
     gene            complement(6943..7392)
                     /locus_tag="C2142_RS08960"
                     /old_locus_tag="C2142_08935"
     CDS             complement(6943..7392)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS08960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_08935"
                     /product="hypothetical protein"
                     /protein_id="WP_148641899.1"
                     /transl_table=11
                     /translation="MTGTVITDLRRRGAVDPGRVLTGPLRVVGLQWLDPGRRTEVAAEG
                     VEHALYITAGSGTATVPDADGQAGPDAAVPLVEGTALTLPLGARTVLTAGTAGLEYFHA
                     VLAVAGRPPGSRAPTGSAGREDPAGPAGRPHHPDHPESPKGGEPR"
     gene            complement(7531..8655)
                     /locus_tag="C2142_RS08965"
                     /old_locus_tag="C2142_08940"
     CDS             complement(7531..8655)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013887.4"
                     /locus_tag="C2142_RS08965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08940"
                     /product="hypothetical protein"
                     /protein_id="WP_148641900.1"
                     /sec_met_domain="DHQ_synthase (E-value: 2e-12, bitscore:
                     45.7, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRTGELDRRIQAGPANFALLVRRGEASWAELADRIAGFGADRFV
                     LVADAAAPADGLARVRAIAAAIAPCTVLTQPGPSPARPSPARPTDDGRTVVIAVGGERA
                     CGVPADIRLPTTLAAACGPALTLLRPPPDAPRAPSPTAPVRTAPALVWVRSDLLAGRPA
                     PETRAGMVEVVRHVLAVCPAQFAALARTLRPDARYTPETLAACVALCADARAALVCFDP
                     FETGPALALGYGRRLGEAVRRTVGTASGVALAPGDADALGLLLAARIAAHLGLLDGAGA
                     WAHNELLARNGSATALPAPPAGADARALAAALTTAAGPGLLLLAGLGRPHCAGGRLLTP
                     VDASALLAAVEGPGRTVVPHSRGPAPESLTAAAG"
     gene            complement(8837..9295)
                     /locus_tag="C2142_RS08970"
                     /old_locus_tag="C2142_08945"
     CDS             complement(8837..9295)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS08970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_08945"
                     /product="hypothetical protein"
                     /protein_id="WP_148641901.1"
                     /transl_table=11
                     /translation="MIVASAVGPRLLLGPGHQRIRTSCLARRGMLHSECESVEHVRLGP
                     GVCYDLAGRDGTEAAWYVLRGTVDLIDCPEQPQRPLGRGVLLLAPSGRDVHLHGGPLGA
                     ELLCVTVLPAEASRALPSRRPPRRPPRRPPRRPPRRPEVGRARPATDG"
     gene            complement(9292..10017)
                     /locus_tag="C2142_RS41480"
                     /old_locus_tag="C2142_08950"
     CDS             complement(9292..10017)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014376.4"
                     /locus_tag="C2142_RS41480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08950"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_148641902.1"
                     /transl_table=11
                     /translation="MRSVRSAVVVADTGTPADVHDVHGAAGVAQWACLARRAGLAGDWE
                     AVEWVRLPPGGVSGEHRHTRTREVDVLLTGNGEITLDGRPYAVGAGDAVLTAAGTRHGL
                     RNLGASALERLVIELPAQWDTAAAVGSTVIRDLRNAGPVDPSAVLGGPLRLLRFARLAP
                     GERDGHAADGVEHTLFVTAGGGRAAAGNVRLPLRPGVALTLPLGSVADLADGPGGLEYV
                     HAELVVERTAGEAAGGGAR"
     gene            complement(10001..11245)
                     /locus_tag="C2142_RS08980"
                     /old_locus_tag="C2142_08955"
     CDS             complement(10001..11245)
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     amglyccycl: salQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359798.1"
                     /locus_tag="C2142_RS08980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08955"
                     /product="sedoheptulose 7-phosphate cyclase"
                     /protein_id="WP_148641903.1"
                     /sec_met_domain="salQ (E-value: 7e-157, bitscore: 520.9,
                     seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 2.9e-54, bitscore:
                     182.8, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAPSAVPPPTARAGTCRTGCNPTGAQATGRTVATALPVRHRVRF
                     VPGVLDPANPALARAGGPPGRRLVVVEARVRELYGRLLHRYPAAQGVEHETLVLPVHEQ
                     VKTMDAVFRVADRMDSSGIYRRGEPVIAIGGGVLADVVGLACSLYRRSTPFVRVPTTLA
                     ALVDAGAGAGATTGVDHGRHGNRLGTYHPAADTLLDPAFLATLDRRHLGNGLAEILQVA
                     LIKDGDLFGLLERHGRALLDEGFRGSHRAGAEVLTRAVRGMLQDLQPGLREHRPARLTD
                     YGHSFSPTVELRALPELLHGEAVCVDMALTTVVAQRRGLLDPEQAERILRLMRRLELPV
                     WHPLVEPVTLAEALADTVRHRDGRQRLPLPAGIGSGVFVDDLTDGELAGAARWLRDRAA
                     ADRVREEHEGREVRA"
     gene            11582..12904
                     /locus_tag="C2142_RS08985"
                     /old_locus_tag="C2142_08960"
     CDS             11582..12904
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019436034.1"
                     /locus_tag="C2142_RS08985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08960"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_148642296.1"
                     /transl_table=11
                     /translation="MNFTDRTDAGRRLAARLGHLRGPGTVVVALPRGGVPVAAEVAAAL
                     GAPLDICVIRKLGVPYQPELGMGAIGEDGVRVLNDQVMRVAGVGAGQLAEVERAERAEL
                     ERRARRYRGDRPPTDLRGRTVVVVDDGVATGSTARAACRIVKARGAARVVLAVPVAPRD
                     WTDRLSDAADELVCVSTPSPFFAIGEFYRDFSQTGDDEVLRLLAAARGEHPHAPTEVDR
                     ELTVPAAGVLLAGRLTVPVRAAGVVVFAHGSGSSRHSPRNRHVAAHLNRAGLATLLFDL
                     LTEAEEPDRRKVFDVDLLGTRLTAVAGRLADQEETRDLPLGLFGASTGAAAALWTAARM
                     GDGVRAVVSRGGRPDLAGPERLAAVTAPTLLVVGGRDTAVIELNRQAQSRLRCESVLAV
                     VPHAGHLFEEPGTLDQAAELARDWFLGRLPADPPGPPGDPA"
     misc_feature    13015..13033
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.37"
                     /tool="antismash"
     gene            13167..14381
                     /gene="hppD"
                     /locus_tag="C2142_RS08990"
                     /old_locus_tag="C2142_08965"
     CDS             13167..14381
                     /EC_number="1.13.11.27"
                     /GO_function="GO:0003868 - 4-hydroxyphenylpyruvate
                     dioxygenase activity [Evidence IEA]"
                     /GO_process="GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hppD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139243.1"
                     /locus_tag="C2142_RS08990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08965"
                     /product="4-hydroxyphenylpyruvate dioxygenase"
                     /protein_id="WP_148641904.1"
                     /transl_table=11
                     /translation="MTPQSHALELTPEEREAGLDADQLRRLVGLVEHDPATDPFPVTAQ
                     DAVVFVVGNATQTAQFYQAVFGMELVAYSGPETGRRDRKAFVLRSGSCRFVIKGGVLPD
                     SPLLDHHRRHGDGVVDLALEVPDVDKCIEHARATGATVLEEPNDVSDENGTVRRAAIAT
                     YGETRHTLIDRSRYHGPYLPGFIAAESKVKHPEGSPKRLFQALDHAVGNVELGRMNEWV
                     SFYNRVMGFVNMAEFVGDDIATDYSALMSKVVASGNHRVKFPLNEPAIAKKRSQIDEYL
                     EFYTGPGCQHMALATNDILTTVDVLRSRGVEFLNTPDSYYDDPELRARIGKVRVDIDEL
                     KKRGILVDRDEDGYLLQIFTKPIGDRPTVFYEFIERHGSLGFGKGNFKALFEAIEREQD
                     ARGNL"
     gene            14437..15636
                     /locus_tag="C2142_RS08995"
                     /old_locus_tag="C2142_08970"
     CDS             14437..15636
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010273861.1"
                     /locus_tag="C2142_RS08995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08970"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_148641905.1"
                     /transl_table=11
                     /translation="MAHYRQLGSIPPKRHTQHRTPEGGLYYEELMGEEGFSSDSSLLYH
                     RGIPSAVVDAVPWELPDQSLVANHPLLPRHLKLHELFAGQEWKSADVVGSRRLVLGNGD
                     VRISYVAAGAPSELYRNGLGDECVYVESGAGTVETVFGTLEVGQGDYVVIPRATTHRWV
                     PSGDEPLRAYCIEANSHITPVKRFLSKYGQLLEHAPYCERDLRGPSGPLLVEGTDVDVL
                     VKHRGPNGIAGTRYTVPHHPFDVVGWDGCLYPYAFNIRDYEPITGRIHQPPPAHQVFEG
                     NGFVICNFVPRKVDYHPLSIPVPYYHANVDSDEVMFYCGGDYAARKGSGIGQGSISLHP
                     GGHTHGPQPGAYERSIGVEFFDELAVMVDTFRPLELGEGGRAGEDADYAWTWAGRGPQR
                     "
     gene            15633..16517
                     /locus_tag="C2142_RS09000"
                     /old_locus_tag="C2142_08975"
     CDS             15633..16517
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C2142_RS09000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C2142_08975"
                     /product="hypothetical protein"
                     /protein_id="WP_206670945.1"
                     /transl_table=11
                     /translation="MTGTFEPAGGGIPPLFQGLFDDAAVFPPGNLPVAEAVPAHRAHRC
                     AWYSAAVGPLLCGAGRLGELAAAAPAGAGGPLRVGLVLPGGSAELGPALAAAAPFEVAG
                     VELATRDAAEAVAALDLLLPPDVPAAVELPRELLHGDALGEVLDVLVDSAYRAKFRTGG
                     VVAGAFPDEDELAGFLTGCAQRGLPYKCTAGLHHAVRHTDPVTGFEHHGFLNVLLAALE
                     TDRRAAAEVLAERSGEALAKAVRELTDHQVTVIRNSFTAFGTCSIAEPLDDLAALGLLS
                     PGTGPSPTSQEDR"
     gene            16514..17734
                     /gene="fahA"
                     /locus_tag="C2142_RS09005"
                     /old_locus_tag="C2142_08980"
     CDS             16514..17734
                     /EC_number="3.7.1.2"
                     /GO_function="GO:0004334 - fumarylacetoacetase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fahA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559014.1"
                     /locus_tag="C2142_RS09005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08980"
                     /product="fumarylacetoacetase"
                     /protein_id="WP_148641906.1"
                     /transl_table=11
                     /translation="MTTPRSWLASAQDSPFGVHNLPYGVFTAADRPGHRRIGVRIGESV
                     LDAGAAARAAGEPSVLLDADTLNPLLGAGRSAWTRTRAALTHWLTDESFRDALSPLLLP
                     VAEVELHLPFEVADYVDFYASEHHATNLGRIFRPGSDPLTPNWKHLPIGYHGRAGTVVV
                     SGTPVVRPHGQRKAPADAVPSFGPTRRLDIEAEVGFVVGTPSTLGTPVTLGDFREHVFG
                     VCLVNDWSARDIQAWEYVPLGPFLGKSFATSVSPWIVPLDALEHARVTPPARDVEPLPY
                     LDDRGGEPWGLDLAMEVRLNGHPVSRPPFASMYWTAAQQLTHMTVNGASLRTGDLFASG
                     TVSGPAPETRGALIELTWNGEEPVKLPDGTTRTFLEDGDEVTITATAPGPDGAVIGFGE
                     VTGRVAP"
     gene            17960..19024
                     /locus_tag="C2142_RS09010"
                     /old_locus_tag="C2142_08985"
     CDS             17960..19024
                     /EC_number="3.1.2.-"
                     /NRPS_PKS="Domain: ECH (9-251). E-value: 1.3e-30. Score:
                     98.4. Matches aSDomain: nrpspksdomains_C2142_RS09010_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378386.1"
                     /locus_tag="C2142_RS09010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08985"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_148641907.1"
                     /transl_table=11
                     /translation="MGAEVLVHQDGGVGRIVLDRPRALNSLTHGMITAVHAALEEWAAD
                     DTVRAVVLTGAGERGLCAGADIRAIHEDAKAGGAGSRAFFRDEYRLNALIARYPKPYLA
                     VMDGITMGGGVGLSAHGAVRIVTERSTVAMPETRIGLVPDVGGSRLLAHAPGGLGTHLG
                     LTSASMGPGDALLCGFADHFVHSARIPALLADLTARLAGPATGAAAAVTAAVTAHAEAA
                     PPAALAAQRAWIDACYGADTAEEIVARLLDTGLPEAKEAAEQVLGNSPTAVKVTLAALR
                     RARTLPSLEAVLDQEYRISCAALAGHDLVEGIRAQVVDKDRNPRWSPAGLAGVSEAEVA
                     RHFAPRGDDELGLA"
     aSDomain        17987..18712
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS09010_ECH.1"
                     /evalue="1.30E-30"
                     /label="C2142_RS09010_ECH.1"
                     /locus_tag="C2142_RS09010"
                     /protein_end="251"
                     /protein_start="9"
                     /score="98.4"
                     /tool="antismash"
                     /translation="DGGVGRIVLDRPRALNSLTHGMITAVHAALEEWAADDTVRAVVLT
                     GAGERGLCAGADIRAIHEDAKAGGAGSRAFFRDEYRLNALIARYPKPYLAVMDGITMGG
                     GVGLSAHGAVRIVTERSTVAMPETRIGLVPDVGGSRLLAHAPGGLGTHLGLTSASMGPG
                     DALLCGFADHFVHSARIPALLADLTARLAGPATGAAAAVTAAVTAHAEAAPPAALAAQR
                     AWIDACYGADTAEEIVARLL"
     misc_feature    complement(19176..19190)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 15.82"
                     /tool="antismash"
     gene            19197..19985
                     /locus_tag="C2142_RS09015"
                     /old_locus_tag="C2142_08990"
     CDS             19197..19985
                     /EC_number="4.2.1.17"
                     /NRPS_PKS="Domain: ECH (12-254). E-value: 1.3e-77. Score:
                     252.3. Matches aSDomain:
                     nrpspksdomains_C2142_RS09015_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740198.1"
                     /locus_tag="C2142_RS09015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2142_08990"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_148641908.1"
                     /transl_table=11
                     /translation="MTETTETYETILVERKGRVGLITLNRPEALNALNTRLMNEVVAAA
                     TAFDRDPEIGCLVITGSEKAFAAGADIKEMQGNRFPDVYLDDWLGPWDRLGELRKPVVA
                     AVAGFALGGGCELAMLCDILLAADTAKFGQPEIKLGVIPGIGGSQRLTRAVGKAKAMEL
                     CLTGRMMGAEEAERAGLVSRIVPADQLLAEALAVAEKVAAMSTPAAIMLKESVNRSFET
                     TLAEGVRFERRLFHAAFATADQKEGMAAFAEKRPASFTHR"
     aSDomain        19233..19958
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C2142_RS09015_ECH.1"
                     /evalue="1.30E-77"
                     /label="C2142_RS09015_ECH.1"
                     /locus_tag="C2142_RS09015"
                     /protein_end="254"
                     /protein_start="12"
                     /score="252.3"
                     /tool="antismash"
                     /translation="VERKGRVGLITLNRPEALNALNTRLMNEVVAAATAFDRDPEIGCL
                     VITGSEKAFAAGADIKEMQGNRFPDVYLDDWLGPWDRLGELRKPVVAAVAGFALGGGCE
                     LAMLCDILLAADTAKFGQPEIKLGVIPGIGGSQRLTRAVGKAKAMELCLTGRMMGAEEA
                     ERAGLVSRIVPADQLLAEALAVAEKVAAMSTPAAIMLKESVNRSFETTLAEGVRFERRL
                     FHAAFATADQKEGMAAFAEK"
ORIGIN
        1 cgagggcgtt gacgacggtg tcgcagagca gcggtggcgc gtcggccggg ctgacggcgc
       61 ggctgagccg ttccgcgagc tcgcgcacca cctggtaggg gcgggcccgg tcaccgtagt
      121 agaaccggtc gacggcgcgg agcacccacc gggcggtcgg gcccagcagt gcgccgatgg
      181 cgagcgtgcc ggccgccagc agctgggcgc cggcggtgct ggcctcgggc agcgcgcggc
      241 gcagcaccag ggcgatgccc aggtagccgg cgatcagcag cgcggtgagg gcgagcacgc
      301 tgagcatccg gcgggtggcg cggtcgaggt agtgggagcg gtcacgggtg aaggcgtagc
      361 cgacggcgcc gagcatccag atcgccgatc cggtgaagta ggcgaccgcg ccgaggctct
      421 ccgaagtgcc catccgcagg gcgaggttgg tggtgaccag ccagaccagg taggggacga
      481 gcaccgccgt gaacgtccgg tgcgggccgg ccgaacgccg ccaccgcacg gcggccacca
      541 gcagactgcc cgtgacgacc gcccaggaga ccagggtgac ccgccactcg tcgagtggca
      601 gcccctcgcc ctgggggacc agcacgtccc cgaagtacgg cagcggcacg ccgagccgca
      661 ccacgcaggc gtggcaggcg ctccagagcg cgatcgcggc aacgaggagg cgtccccggc
      721 ctccgggcag ccggccctcg ggcagccaga gcggcagggc gagggccagg aagatgaaca
      781 gggtgaccga gacgagcagc agcgccgcac cgaccgcctc cggcaccggt ccggcgccgg
      841 ccgatgcggc ggccagcagg tagaaccggg agagacagcc gccgagtccg gcggcgagca
      901 tcgtcacgcc gaggctgcgg ccggcgggga ggggggcctc gggggcggcg cgggccgctc
      961 cgggggcgga cgtcgcggcg acggcgcgcc ggcgcctggg gcggcgggcc gtggggcgcg
     1021 gggccggggc agcgggtgcc ggttcgcccc cggggcccgg gcggtgggcg aggatcagca
     1081 ggccggagag cgcgaaggcg aacccgagca gcaccgtctc gccgtcgtgc aggaagaacg
     1141 gctcggccca ggcggcgttc tggtgggtca gggccagcag cacccagccg aggccgcaga
     1201 ccagcgtcag cccgcacatc caggtggcaa gggtgaggcc ggtccgcccc ggccggaggg
     1261 cggtggcccg gacggtggtg gccgcggccg gttcactcat gtgggcctcc ctgttggcct
     1321 ccccgcgggc gcctccgtgc ggggcccgcg gggcttccgg gctccgccgc ggcggagccc
     1381 gggccgggtc aggtgtcgcc gaggcccatg tcccgggccc gggcgaccgc ctcggcgcgg
     1441 gtcgccacgt gcagcttctc gaagatgtgg gtcacgtggt tgcggaccgt cttctccgcc
     1501 accaccagct cgcgggcgat ccgccggttg tcgagccccc gcgccaccag gtccagcacc
     1561 tcggcctcgc gggcggtcag ggacgggaac agctgtccgg cttcgcgcag ccgggctccg
     1621 gccagcagcg cggtgatccg gccggccacg tccgcaccga acaccgcgcc gcccgccgcg
     1681 accgtccgca cggcgtgcag cacctcctcc cggcccgcgc ccttgaccag gtagccgcgc
     1741 gcacctgcct ggagagcggc cagcaggctg ccgtcgtcgt cggccatggt gagcatcagc
     1801 accggcgggg ccggcggctg ggcggccagc cggcgggcgg cctccagccc ggagccgtcc
     1861 ggcagtgaga ggtccatcac caccacgtcc gggcggtacc gggcgaccgc gtccggcacc
     1921 gcaccggccc gctcggcctc ggcgaccacg gcgatgccct cggcgctctg cagcgcggcc
     1981 ttcagtccct cgcggaacag cgggtggtcg tcgacgatca ggacccggac gggtgacgcg
     2041 tcggtgcccc gttcaccgcc cgtcgcatcc tccccggtcc gttccccgcc cgccccctcg
     2101 tccgtcccgc cggccggacg accgtcgcgc tccccgggca gctcgtccca ccggccggcg
     2161 gtgggcgaac cggcggtggg cgaaccggcg ggcccggcac cggggccgta ccgcggggcg
     2221 ccctgcggcg cgtcccgggg gccgggggcc ggctgcggag cgggctgggc tggggagtgc
     2281 tgttggtcca catggccgac actaccagcg atgacggagt gactttccgt gacatgctcg
     2341 gagtgtcgcc cggtccgtcc ggaccacccg cccccgggac gagaccgctg cctcatgcgc
     2401 ccgggacggc gggccgacga gactgtcgtc catgcccggc gaacggccgt cggcggacca
     2461 cacaccccag cccgttgcga ggcggtgcca tgatcacggt gacctctgcc cgaccccgcg
     2521 cgtccgcccg gcgcaccccc cgccggactc cggcccagcg gcagctgacc gccgccgcgg
     2581 tctgcacggc gttctgcctc gccgtcgcca cgctctggat ctgctacgtc ctggtgcacc
     2641 tcggcgaacc gggcgtcgcc cgcccccggg accagctcgc catcctgctc tacgcactgc
     2701 ccaccgccgg cgccggcatg ctgctgcacg cccaccgccc gggcagcccg ctcgggtggg
     2761 tcatgctggc ctacgccctc acctcgatgc tgcccagcgc ggccggcgcg tcgctctggg
     2821 tggaggtctc cgacccgggg ctggtgggcg cgctcgcggt gctgcgctcg gtctgcgaca
     2881 ccatcagcca gacgctcttc tacgtgctgc cgctctggct cccctccggg cggctcacca
     2941 cgcgccggtg gtggctctac atcggcgccg tcgcgctctg ggagatcccg gacggcatgt
     3001 cgttcctcgg ccacgcgacc tcctacggcc accccaaccc gctcgccgac agcccgcccg
     3061 ccgccttctt cggggcgctc tcggaccacc tggacggcct ctacgacccg gtgaactacc
     3121 tgctcgtcgg gttctcggcc gccgtactgc tgttccggct gctgcggccg gcgccggacg
     3181 gccccccgga cgggcccgcg ccgcacccgg cgcaccgggt gcacgtggcg gcgatgctcg
     3241 gcgcgtacct gctctgggcg ggcatgcagg actactacaa ccgccgcttc cagtacgagt
     3301 actggctcag ctactcgctc ttcgccgccg ccggggcggt ctgggcggtc gccgtggcgt
     3361 acctggtgat ccgggacggc ggctggcggc tggaccgggc ggcccggtcc gtgctgaccg
     3421 ggctgctcct ggccaccggg ctgaccacgg tgttcgtggt gttcgccgcc gtgctctccg
     3481 gctggctggt accgggccgg ggaggagcgg cgctggtgtt gatcgccctg gtgttcgggc
     3541 tgggcagctg cctgccccgg cctgcccggt gggcggtcgg actggtcgac cgcctctact
     3601 acggcgaccg cgcccagccg taccaggtgc tgcgcaccct ggccgggcag gtccggcaga
     3661 ccgtcgaccc cgagcggctg ccggcggcac tctgcgccac ggtcgccgag gagctgcggc
     3721 tgcccggggt cgcactgagc gtcaccaccc gggccgggcg gcgccggctg gccgccgtcg
     3781 gccggctgga cgggcccggg caggccttcg cgctggtcca ccacggcacg gtgatcgggg
     3841 agttgacggt cgcaccgcgc gagggcgagg agcggctgga cccgggcgac atcgacatcc
     3901 tgcgctcgct cgccgaccag gtctcgcccg cggtcgcctc gctgcaactg caggaggacc
     3961 tccaggcgag ccgggagcag atcgtcgcgg cgcgggagga ggagcggcgc tggctgcgcc
     4021 gggacatcca cgacggcctc gggcccgcgc tggcggggct gcggctgcgg gtggacaacg
     4081 ccgcctcggg agccgcctcg gaagccgccg ggagcgccgt cccccggagc ggcccgggcg
     4141 cgggccttgc ggagaccctg cacgggatct cgggggacct cgcgatggcg atcaaggagg
     4201 tccggcggat caccgaccgg ctcgggccgg ccccgctcgg cgagttcggg ctcgcgcggg
     4261 ccgtccagca gctcgccgcc aacttcagcg gcgccgcgct ggccgtcacc gtctcgatgg
     4321 ccccggaccc gttgccggac ctgccggccg ccgtcgaggt ggccgcctac cggatcaccg
     4381 ccgaggcgct gaacaacgtc ctgcgccacg cccgcgcccg acgcgcccag gtgtgcgtcc
     4441 gggtggacgc ggagacgctc acgctgaccg tgcaggacga cggggtgggg gtggagacgg
     4501 gggaaacgac ctgggcggag cgcctgccgg aggaggccgc gcagagcacg ggcgggacgt
     4561 ccgggtgggc gggcggcggg gtcggcctcc ggtcgatggc cgaccgcgcg gcggagatcg
     4621 gcggcaggtg cacggtggcg ccccgggcgg gggagcacgg gacgcgggtg ctggcggtgc
     4681 tgccccggtt cccgtcggcg ggcggggcgg ccggggcgcg acgggagacg gccggcggct
     4741 gaccgcccac cgcgcgacga ccgcccccgg cgctcgcggc gccgggggcg ggtctggctc
     4801 gggggtcggg atcggggtcg gggtcgggag tggggggggg nnnnnnnnnn aagggcggcg
     4861 ggaggactca gcccttgcag tccgtctcac cggccttgca cctcctgttc ttcgcgacgg
     4921 gccgcgtcct gttcttcgcg acgggccgcg ccgtcctcct cgccgtggac tccggcgtcc
     4981 ggcaggacct cgccgttgcg ccgacgacgg tgctcttgag tacgaaggtc gccgctgcgc
     5041 agccgacgac gaccgacgcg acgccgagcg tcttcctcgc ggtgttcgtt gccatgggtg
     5101 gtgctccaga ctcttcgtct tccgggcggc cgggcgggcc ggccgctctt ccaccactgt
     5161 gcgcgggggc ctgccccggg cacatgggcc cgccgtcccg ttccggtccc agggtgcggg
     5221 tccgaagccg ggacggcggg cgtccgtgca ggccggggcg gggtcagcgg ctgccggtcc
     5281 aggggcctcc ggacgtgaac agccggtcgg cggtggtgcg ttcgtagggc gcggtgacat
     5341 cgacgacccg cccgccccgg ccctggcggg ccgtccggcg ggcggcggag cggtcggcgc
     5401 ggcagccggt cgcggccgcg tggccggccc gggccggcgc gatggccgtg gcccggccga
     5461 tgccggaacc ggtgacggtg acggtgacgg tggcggtgac gactgcggcc gcgcccggca
     5521 gcacgccccg gccggtgtcg gtcccgggcg tgttcatcgc agcacctcct ccgcggccgg
     5581 ccggacctgg tagccggccc gggccggact cgccgcgccc aggtagccgt acacggcggc
     5641 ggtcggatgt cccggaccgg cccggaagcc gtgccactcc cccgccggga cgtacaccag
     5701 gtcgcccggg cggaccgcga cctcgcgggt cgcggcgagg tgccggccac cgcccgcgag
     5761 gacgaggaag aactggtccg cgtgcgggtg ccggtgcagt tcgtggctgc cgccgggggc
     5821 gaacccgaag gccgcgacgg cgacctgccg ggcgcccacc gtctccgcgg tggcgagcca
     5881 gtgcacggcc gtcccggccg cgcctccggc ggccgggccg tcctcccctt cgggcgggcc
     5941 ggtccgtcgt gacggggccg cgagcggcac tactgacagg cccggcacgg gccgtgggcc
     6001 ggccgacggg cctgcccgga cggtcaggac gacggccggg gcgccgggca gcacggcgag
     6061 tccgcagtcg ctgcccggcg ggtggtagag gccttcgccg gggccgagga cccggccggc
     6121 cgagcggacc cggccggaga gcaccacggt caccgactcg ccggccgggg cgggccgttg
     6181 cccgacgcgg acgccgggcg acagggtctc gacgctcagc ccgccgaggg cggacggcag
     6241 gtggcgtggg tcgatcagcc agcggaacgc gggggccgtc cgggggacgg ctgcggggac
     6301 gaggatcacg tcattcctcc ttgcggggtt cggtgttcac cggcgctccg gtgtccgccg
     6361 gtggtgcggt gtcctccggt gctctggcgg tgcagtgctc cccggtggtg cgtggtccgc
     6421 cgggcgtggg gccgcggcgg gaagcggtgc ggccgtcgcg cagggaggac gcggcgccgg
     6481 gcctcgaagt gcagggcggt cgtggtgcgg gccggcccgg gggcggtgac ggcgttcacg
     6541 gcctggtccg tcgttcggcg cggcggcggg ccagggcgtc cctggtcgcc gaggcgcggc
     6601 ggggtgcggc gagggcgagg cagagcagct cggcgccgag cggtccggcg tccaggtgca
     6661 gcggggtccc ccggcgggcc agcagcaggt ccccgtcgac cgccaggtgg tccggctcgt
     6721 cgggggaccc gccgaccagg agggagccac gcagcacgta gaggacgttc tcggtctcgt
     6781 tctgtcccgg cagcacgtgg tgggctccgg ggctcagccg caggtggtcg aaggactcgc
     6841 aggcgccggc gagcatcgaa cggcgggcca ggcagcgcag ccggatccgt tcgccgtgcg
     6901 gaccgaggat gacggcggcg gcggccgagg cggtggtgat gatcacctgg gctcgcctcc
     6961 cttcgggctt tcggggtggt ccgggtggtg gggccggccg gccgggcccg ccgggtcctc
     7021 tcggcccgcc gagccggtgg gggcccggga gcctggcggg cgcccggcga cggcgaggac
     7081 ggcgtggaag tactccaggc ccgcggtgcc ggcggtcagg accgtccggg cgccgagcgg
     7141 cagggtcaac gcggtgccct cgaccagcgg gaccgcggca tcggggcccg cctgcccgtc
     7201 ggcgtccggg acggtcgccg tgcccgagcc ggcggtgatg tagagggcgt gttccacgcc
     7261 ttcggcggcc acctcggtcc tgcggcccgg gtcgagccac tggaggccga ccacgcgcag
     7321 cgggccggtc aggacgcggc ccgggtcgac ggcgccgcgg cggcggaggt ccgtgatgac
     7381 ggtgcccgtc atgacgtgaa ctcccttctg gtctccggcg gtccgtgccg gtccgcctct
     7441 gctgtccacg gtgtggcgcc cgccgtcccg gccgcacggg gagccggtcc cgtcctgttc
     7501 ccggccgccg cccgagcccc gcgcgccggg tcatccggcg gcagcggtca ggctctccgg
     7561 ggcggggccg cggctgtgcg gaacgacggt ccggcccggt ccctcgacgg ccgccaggag
     7621 cgcggaggcg tcgaccgggg tgagcaggcg gccccctgcg cagtgcgggc gcccgagccc
     7681 ggcgagcagc agcaggccgg gcccggccgc ggtggtgagg gccgcggcca gggcccgggc
     7741 gtcggccccg gcgggcggcg cgggcagggc ggtcgccgag ccgttgcggg ccagcagttc
     7801 gttgtgggcc catgccccgg cgccgtccag cagtccgagg tgggccgcga tgcgggcggc
     7861 gaggagcagc cccagggcgt cggcgtcgcc cggtgcgagc gccacgccgg aggcggtgcc
     7921 cacggttctg cggacggcct cgccgaggcg gcgcccgtag ccgagcgcga gggccggtcc
     7981 ggtctcgaac gggtcgaagc agaccagcgc ggccctggcg tccgcacaga gggcgacgca
     8041 ggcggcaagg gtctccgggg tgtaacgggc gtccgggcga agggttctgg cgagcgccgc
     8101 gaactgtgcc gggcagacgg cgaggacgtg ccggacgacc tcgaccatgc ccgcccgggt
     8161 ctcgggggcg ggacgtccgg ccagcaggtc gctgcggacc cagaccagcg cgggcgcggt
     8221 ccggacgggt gcggtcgggg agggcgcacg gggtgcgtcc gggggcgggc gcagcagggt
     8281 gagtgccggg ccgcacgcgg ccgcgagggt ggtcggcaga cggatgtcgg ccgggacacc
     8341 gcaggcccgt tcgccgccga ccgcgatcac cacggtgcgg ccgtcgtcgg tcggccgggc
     8401 gggtgacggc cgggcgggtg acgggccggg ctgtgtgagc acggtgcacg gcgcgatcgc
     8461 cgcggcgatg gcgcggaccc gggcgagccc gtcggcggga gcggcggcgt cggccaccag
     8521 gacgaagcgg tcggccccga acccggcgat ccggtcggcg agttccgccc aggaggcttc
     8581 gccgcggcgt accagcaggg cgaagttcgc gggtccggcc tgtatgcggc ggtcgagttc
     8641 gccggtgcgg cccatcgtgg tcctcctcca gccgggtctc cgacctcgac catgggccgc
     8701 ccgacgcccc gggcacctga gccgccgttc ccgtcccggt cggtcccggg acggcccggt
     8761 tcccgtccgg gacgggacct gccggaacgg gacctgccgg aaccgaccgg gagggacccc
     8821 ccgggacggc aacggttcaa ccgtcggtcg ccggccgcgc ccgcccgacc tccggccggc
     8881 ggggcggccg gcggggcggc cggcggggcg ggcggcgggg cgggcggcgg gacggcagtg
     8941 cccgactcgc ctccgccggc aggacggtga cgcagagcag ctccgcgccg agcggccccc
     9001 cgtgcaggtg cacgtcccgc ccgctcgggg ccagcagcag gacgcccctc ccgaggggcc
     9061 gctgcggctg ctccgggcag tcgatcaggt cgacggtccc ccgcagcacg taccaggcgg
     9121 cctcggtgcc gtcgcgcccg gcgaggtcgt agcagactcc cggcccgagc cggacgtgct
     9181 cgacggactc gcactcgctg tgcagcatgc cccggcgggc gaggcagctg gtccggatgc
     9241 gctgatggcc gggcccgagc agcagccggg gtccgacggc gctcgcgacg atcaccgcgc
     9301 accaccccct gcggcctccc ccgccgtccg ctccaccacg agctcggcgt gcacgtactc
     9361 caggccgccc gggccgtccg ccaggtccgc cacgcttccg agcggcaggg tgagcgccac
     9421 ccccgggcgc agcggcagcc gcacgttccc ggccgcggcc cggccgcccc cggcggtgac
     9481 gaagagcgtg tgctcgacgc cgtcggcggc atggccgtcc cgctcccccg gggcgagccg
     9541 ggcgaaccgc aacaggcgca gcggaccgcc gaggacggcg gacgggtcca ccggaccggc
     9601 gttccgcagg tcccggatca ccgtgctgcc caccgcggcg gcggtgtccc actgtgcggg
     9661 cagctcgatc accagccgct ccagcgcgga cgccccgagg ttgcgcaggc cgtgccgggt
     9721 gccggccgcg gtcagcaccg cgtctccggc gccgacggcg tacgggcggc cgtcgagcgt
     9781 gatctcgccg ttccccgtga gcaggacgtc gacctcccgg gtgcgggtgt gccggtgctc
     9841 cccgctgacg ccgccgggcg ggaggcgcac ccactcgacg gcctcccagt ccccggccag
     9901 cccggcgcgg cgggccaggc aggcccactg cgcgaccccg gccgcgccgt ggacatcgtg
     9961 gacgtcggcg ggcgtgccgg tgtccgcgac cacgaccgcg ctacgcacgg acctcacgtc
    10021 cctcgtgctc ctcccggacc cggtcggccg ccgcccggtc ccgcaaccac cgggcggccc
    10081 cggccagctc gccgtccgtc aggtcgtcga cgaacacgcc ggagccgatc cccgcgggca
    10141 gcggcagccg ctgccggccg tcccggtggc ggacggtgtc ggcgagcgcc tcggcgagcg
    10201 tgaccggttc gaccagcggg tgccagacgg gcagttcgag acggcgcatc agccggagga
    10261 tccgctcggc ctgctccggg tcgagcaggc cgcggcgctg ggcgacgacg gtcgtgagcg
    10321 ccatgtcgac gcagaccgcc tcgccgtgca gcagctcggg cagcgcgcgc agctcgaccg
    10381 tcgggctgaa cgagtggccg tagtccgtca gccgcgccgg ccggtgctcc cggagaccgg
    10441 gctgcaagtc ctggagcatt ccgcgcacgg cccgggtgag cacctcggca ccggcgcggt
    10501 ggctgccccg gaagccttcg tccaggaggg cgcggccgtg ccgttcgagc agcccgaaga
    10561 ggtccccgtc cttgatcagc gccacctgga ggatctcggc gagcccgttc ccgaggtgcc
    10621 ggcggtccag ggtggcgagg aatgccgggt cgagcagggt gtcggcggca gggtggtagg
    10681 tgccgagccg gttcccgtgc cgcccgtggt cgacgcccgt cgtggcgccg gcgccggcgc
    10741 ccgcgtccac cagcgcggcc agggtggtgg gtacccggac gaacggtgtc gagcgccggt
    10801 agaggctgca cgcgaggccg acgacgtcgg ccagcacgcc gccgccgatc gcgatcaccg
    10861 gctcgccgcg ccggtagatg ccggaggagt ccatccggtc ggcgacccgg aacaccgcgt
    10921 ccatggtctt gacctgctcg tgcacgggca gcaccagcgt ctcgtgctcg accccctggg
    10981 cggccgggta gcggtggagg aggcggccgt agagctcgcg cacccgggcc tccacgacga
    11041 ccaggcgccg cccgggcggc ccgccggccc gggccagagc ggggttggcc gggtccagca
    11101 cgccgggcac gaagcggacc cggtggcgga cgggcagtgc ggtggccacc gtccggccgg
    11161 tggcctgggc gccggtgggg ttgcagcccg tgcggcaggt cccggcccgg gccgtcggcg
    11221 gcggaacggc tgacggcgcc ggcacggccc gcggggtcgg cggacgggtc gtgcgggtgg
    11281 gggacggtca cggcgtggct ccttctccgt cggctcgctg cttctccgcc ggttctccgc
    11341 gtcgggcgcg tcccggcgtc ccggccccgt gcgcttcggg cacgtccggg cctcggggcc
    11401 gtccggtgtg gcggcgccgg acggcctgcc cccacggtcc ggtgcccgcc gtcccgggcg
    11461 cacgggtgtc cggccccgtc cgcgtcccgg tggtggcttg ggacggcccc gccgggcgcc
    11521 cccacgcccg ccccgccgac gtacggtgga actcggaggc cgcgccatgc acgtcaccgg
    11581 gatcaacttc accgaccgca ccgacgcggg ccgccggctg gccgcccgcc tgggccacct
    11641 gcgcgggccc ggcaccgtcg tcgtcgccct cccgcgcggc ggcgtgccgg tggccgccga
    11701 ggtggcggcc gcgctcggcg ccccgctcga catctgcgtg atccgcaagc tcggcgtgcc
    11761 ctaccagccg gagctgggga tgggcgcgat cggcgaggac ggcgtcaggg tgctgaacga
    11821 ccaggtgatg cgcgtcgccg gggtcggcgc cgggcagctc gccgaggtgg agcgggcgga
    11881 gcgcgccgag ctggagcgcc gggcccgccg ctaccggggc gaccgcccgc ccaccgacct
    11941 gcgcggacgc accgtggtcg tggtcgacga cggcgtcgcg accggctcca ccgcccgggc
    12001 ggcctgccgg atcgtcaagg ccaggggcgc ggcccgggtc gtgctggccg tcccggtggc
    12061 gccccgggac tggaccgacc ggctctccga cgccgccgac gaactggtct gcgtgagtac
    12121 gccgtcgccg ttcttcgcga tcggcgagtt ctaccgcgac ttctcgcaga ccggtgacga
    12181 cgaggtgctg cggctgctcg ccgcggcccg cggcgagcac ccccacgcgc cgaccgaggt
    12241 ggaccgcgag ctcaccgtgc cggccgccgg cgtgctgctg gcgggccggc tgaccgtccc
    12301 ggtgcgggcg gcgggcgtgg tggtgttcgc gcacggcagc ggcagcagcc gccacagccc
    12361 gcgcaaccgc cacgtggccg cccacctgaa ccgcgcgggc ctggcgacgc tgctgttcga
    12421 cctgctcacc gaggccgagg agccggaccg gcgcaaggtc ttcgacgtcg acctgctcgg
    12481 cacccggctg acggccgtcg ccgggcggct ggcggaccag gaggagaccc gggacctccc
    12541 gctcggcctc ttcggcgcca gcaccggcgc cgccgccgcg ctctggacgg ccgcccggat
    12601 gggcgacggc gtgcgcgccg tggtctcccg gggcgggcgg ccggacctcg ccggccccga
    12661 gcggctggcc gcggtcaccg cgccgacgct gctggtggtg gggggccggg acaccgcggt
    12721 gatcgagctg aaccggcagg cgcagtcccg gctgcgctgc gagagtgtac tggcggtggt
    12781 cccgcacgca ggccacctgt tcgaggagcc gggcacgctg gaccaggccg cggagctggc
    12841 ccgcgactgg ttcctgggcc gccttccggc cgacccgccg gggccgcccg gcgacccggc
    12901 ctgaccgggc cggcggggcc ggccgtcggc gcggacggga ggtgcgggca ggttttccgc
    12961 agcagccccg atcggcagca cattttgccc agccgaaccg gggatttcct gatcagcttg
    13021 tacacattga acagtgaaaa agcgacctgt tgcccaacca ccccgacagg agcaagctct
    13081 ccgctcagcc gcaccgccca ccctacgcgg cgcggccgcc tcaagcggat gcctcagagc
    13141 cgaggcccaa agtggaggaa cgaccgatga ccccgcagtc ccacgccctt gagctgaccc
    13201 ccgaggagcg cgaggccggc ctcgacgccg accagctgcg ccgcctcgtc ggcctcgtcg
    13261 agcacgaccc ggccaccgac ccgttccccg tgaccgccca ggacgcggtc gtcttcgtgg
    13321 tcggcaacgc cacccagacg gcgcagttct accaggccgt gttcggcatg gagctggtcg
    13381 cctactccgg cccggagacc ggccgccgcg accgcaaggc cttcgtgctc cgctccggct
    13441 cctgccgctt cgtgatcaag ggcggtgtgc tgccggacag cccgctgctg gaccaccacc
    13501 gccgccacgg cgacggcgtc gtcgacctgg ccctggaggt gccggacgtc gacaagtgca
    13561 tcgagcacgc ccgcgcgacc ggtgccaccg tcctggagga gccgaacgac gtctcggacg
    13621 agaacggcac cgtgcgccgc gccgcgatcg ccacctacgg cgagacccgg cacaccctga
    13681 tcgaccgctc ccgctaccac ggcccctacc tgcccggctt catcgcggcc gagagcaagg
    13741 tcaagcaccc ggagggctcg ccgaagcgcc tcttccaggc gctcgaccac gccgtcggca
    13801 acgtcgagct cggcaggatg aacgagtggg tctcgttcta caaccgcgtc atgggcttcg
    13861 tgaacatggc cgagttcgtc ggcgacgaca tcgccaccga ctactccgcg ctgatgtcca
    13921 aggtcgtcgc cagcggcaac caccgggtga agttcccgct caacgagccg gccatcgcca
    13981 agaagcgctc gcagatcgac gagtacctgg agttctacac cggccccggc tgccagcaca
    14041 tggcgctcgc caccaacgac atcctcacca ccgtggacgt gctgcgttcg cgcggcgtcg
    14101 agttcctcaa cacgccggac tcgtactacg acgacccgga gctgcgggcc cggatcggca
    14161 aggtccgggt cgacatcgac gagctgaaga agcgcggcat cctggtcgac cgcgacgagg
    14221 acggctacct gctgcagatc ttcaccaagc cgatcggcga ccgcccgacc gtcttctacg
    14281 agttcatcga gcgccacggt tcgctgggct tcggcaaggg caacttcaag gcgctgttcg
    14341 aggcgatcga gcgcgagcag gacgcccgcg gcaacctgtg agcgtcgggg aacggtgagc
    14401 acggccggct gagcacggcc gaggaggagc aggacgatgg cgcactaccg gcagctgggc
    14461 agcatcccgc ccaagcggca cacccagcac cgcacgcccg aaggcggtct gtactacgag
    14521 gagttgatgg gcgaggaggg gttctcctcg gactcctcgc tgctctacca ccggggcatc
    14581 ccctcggccg tcgtggacgc ggtgccgtgg gagctgcccg accagtcgct ggtggccaac
    14641 catcccctgc tcccccggca cctcaagctg cacgagctgt tcgcgggcca ggagtggaag
    14701 tccgcggacg tcgtcggcag ccgccgtctc gtcctcggca acggcgacgt gcggatctcg
    14761 tacgtcgccg ccggggcccc gagcgagctg taccgcaacg ggctcggcga cgagtgcgtg
    14821 tacgtggagt ccggcgcggg cacggtcgag acggtcttcg gcacgctgga ggtcggccag
    14881 ggcgactacg tggtcatccc ccgggcgacc acccaccgct gggtgccctc cggcgacgag
    14941 ccgctgcggg cgtactgcat cgaggcgaac agccacatca ccccggtgaa gcgcttcctc
    15001 tccaagtacg gccagctgct ggagcacgcg ccgtactgcg agcgggacct gcgcggcccg
    15061 tccggcccgc tgctggtcga gggcacggac gtcgacgtgc tggtcaagca ccgcggcccg
    15121 aacggcatcg cgggcacccg gtacacggtg ccgcaccacc cgttcgacgt ggtcggctgg
    15181 gacggctgcc tctacccgta cgcgttcaac atccgggact acgagccgat caccggccgg
    15241 atccaccagc cgccgcccgc gcaccaggtg ttcgagggca acgggttcgt gatctgcaac
    15301 ttcgtgcccc gcaaggtgga ctaccacccg ctctcgatcc ccgtcccgta ctaccacgcc
    15361 aacgtggaca gcgacgaggt catgttctac tgcggcggcg actacgcggc ccgcaagggt
    15421 tcgggcatcg gccagggctc gatctcgctg cacccgggcg gccacaccca cggcccgcag
    15481 ccgggcgcct acgagcgcag catcggcgtg gagttcttcg acgagctcgc cgtcatggtg
    15541 gacaccttcc gcccgctgga gctgggcgag ggcggccggg ccggcgagga cgccgactac
    15601 gcctggacgt gggccggccg ggggccgcag cggtgaccgg taccttcgag cccgccggtg
    15661 gcggcatccc cccgctcttc cagggcctct tcgacgacgc ggcggtgttc ccgccgggga
    15721 acctgccggt cgccgaggcg gtaccggcgc accgtgcgca ccgctgcgcg tggtactccg
    15781 ccgcggtcgg accgctcctg tgcggggcgg gccggctcgg cgagctggcc gccgcggccc
    15841 cggccggcgc gggcgggccg ctccgggtcg ggctcgtcct gccggggggc agtgccgagc
    15901 tcggcccggc actcgccgcc gccgcgccgt tcgaggtggc cggcgtcgag ctggccaccc
    15961 gggacgccgc cgaggcggtg gccgcactgg acctgctgct gccgccggac gtcccggccg
    16021 ccgtcgagct gccgcgcgag ctgctgcacg gcgacgccct gggcgaggtc ctggacgtgc
    16081 tcgtcgacag cgcctaccgg gcgaagttcc gcaccggcgg ggtggtggcc ggcgccttcc
    16141 ccgacgagga cgagctggcc gggtttctca ccggctgcgc gcagcgcggc ctgccgtaca
    16201 agtgcacggc ggggctgcac cacgccgtcc ggcacaccga cccggtcacc ggcttcgagc
    16261 accacggctt cctgaacgtc ctgctggccg cgctggagac cgaccgccgg gccgcggccg
    16321 aggtgctggc ggagcgctcg ggcgaggcgc tggccaaggc cgtccgcgaa ctgaccgacc
    16381 atcaggtcac ggtgatccgc aactcgttca ccgcgttcgg cacctgtagc atcgccgagc
    16441 ccctggacga cctggccgcg ctcggcctgc tgtcgcccgg gaccggcccc agccccacgt
    16501 cccaggagga ccgttgacca cgccccgcag ctggctcgcc agcgcccagg actcgccgtt
    16561 cggcgtgcac aacctgccgt acggcgtctt cacggccgcc gaccggccgg gccaccggcg
    16621 gatcggcgtg cgcatcgggg agtccgtcct cgacgccggg gccgccgccc gggccgccgg
    16681 ggagccgtcc gtcctgctgg acgccgacac cctcaacccg ctgctgggcg cgggccgttc
    16741 ggcctggacc cggacccgcg cggcactgac gcactggctc accgacgagt cgttccggga
    16801 cgcgctctcg ccgctgctgc tgccggtggc cgaggtggag ctccacctgc cgttcgaggt
    16861 cgccgactac gtcgacttct acgcctccga gcaccacgcc accaacctgg gccggatctt
    16921 ccgccccggg tcggacccgc tcacccccaa ctggaagcac ctgccgatcg gttaccacgg
    16981 ccgggcgggg acggtcgtgg tctccggcac cccggtggtc cgaccgcacg gacagcgcaa
    17041 ggcgcccgcc gacgcggtgc cgtccttcgg cccgacccgc cggctggaca tcgaggcgga
    17101 ggtcggcttc gtggtcggca ccccgtccac gctcggcact cccgtcaccc tcggcgactt
    17161 ccgcgagcac gtgttcggcg tctgcctggt caacgactgg tcggcgcgcg acatccaggc
    17221 ctgggagtac gtgccgctcg gcccgttcct cggcaagtcc ttcgccacct cggtctcgcc
    17281 gtggatcgtg ccgctggacg ccctggagca cgcccgggtc accccgccgg cccgggacgt
    17341 cgagccgctc ccctacctgg acgaccgggg cggcgaaccc tggggcctgg acctggcgat
    17401 ggaggtccgc ctgaacgggc acccggtctc ccgcccgccg ttcgcctcga tgtactggac
    17461 ggcggcgcag cagctcaccc acatgacggt gaacggcgcc tccctgcgca ccggcgacct
    17521 cttcgcctcg ggcaccgtct ccggccccgc cccggagacc cgcggcgcac tgatcgagct
    17581 cacctggaac ggcgaggagc cggtcaagct ccccgacggc accacccgca ccttcctgga
    17641 ggacggggac gaggtcacca tcaccgccac cgcccccggc ccggacggcg cggtgatcgg
    17701 cttcggcgag gtcaccggcc gggtcgcgcc gtagcggccc gcgcggcggc gggcccggac
    17761 acggacgacc cgtgggcgga gggacggtac cggttgaccg gtgccgcccc tccgcccgtc
    17821 cggggacggg tcccggcccg cccccggact cccgtcgtcc gcccggtcgc ccggcgggcg
    17881 ggagcctgga gccgggccta gtacggtgga cggcgaggat cttcggaacg agcggcgacg
    17941 aggaacggga gcgggcccga tgggtgcaga ggtgctggtc caccaggacg gcggcgtcgg
    18001 gcggatcgtg ctcgaccggc cgcgggcgct caactcgctg acgcacggca tgatcacggc
    18061 cgtccacgcg gcgctggagg agtgggcggc ggacgacacc gtgcgggccg tggtgctgac
    18121 cggcgccggc gagcgcgggc tctgcgccgg cgcggacatc cgggcgatcc acgaggacgc
    18181 caaggccggc ggggccggtt cgcgggcctt cttccgcgac gagtaccggc tcaacgcgct
    18241 gatcgcccgc tacccgaagc cgtacctcgc ggtgatggac ggcatcacca tgggcggcgg
    18301 cgtcggcctc tccgcccacg gcgccgtgcg gatcgtcacc gagcgctcca ccgtggcgat
    18361 gccggagacc cggatcggcc tggtgccgga cgtcggcggc agccggctcc tggcccacgc
    18421 cccgggcggg ttgggcacgc acctcggcct cacgtccgcc tcgatgggcc ccggggacgc
    18481 gctgctctgc ggcttcgcgg accacttcgt ccactcggcg cggatccccg cgctgctcgc
    18541 ggacctgacc gcacggctcg ccgggccggc caccggggcc gcggccgccg tcaccgccgc
    18601 cgtcaccgcc cacgccgagg ccgcaccgcc cgccgcgctc gcggcgcagc gggcgtggat
    18661 cgacgcctgc tacggcgccg acaccgccga ggagatcgtc gcgcggctgc tggacacggg
    18721 gctcccggag gccaaggagg ccgccgagca ggtgctcggg aactcgccga cggccgtcaa
    18781 ggtcacgctc gccgcgctgc gccgggcccg cacgctgcca tcgctggagg cggtgctgga
    18841 ccaggagtac cggatctcct gcgcggccct ggccgggcac gacctggtcg agggcatccg
    18901 cgcccaggtc gtggacaagg accgcaaccc gcgctggtcg cccgccggcc tcgccggggt
    18961 gtcggaggcg gaggtcgccc gccacttcgc gccgcgcggg gacgacgagc tgggcctggc
    19021 ctgaccgggc ccggcggccc cgccccgcac gacggcgccg gaccgcgtcg gcggcgcctc
    19081 ccgtgacgac cgtctcgcat ggcaagactg gcgcgagcgg gggtgcttcg gagattgttg
    19141 ggcggtcagg gcgcaccttg cacggtgccg agcagcggaa atgggagtca acggcgatga
    19201 ccgagaccac cgagacctac gagacgatcc tggtcgagcg caagggccgg gtcgggctga
    19261 tcacgctcaa ccggccggag gcgctcaacg cgctgaacac ccggctgatg aacgaggtcg
    19321 tcgcggccgc caccgccttc gaccgggacc cggagatcgg ctgtctcgtg atcaccggat
    19381 cggagaaggc cttcgcggcc ggcgccgaca tcaaggagat gcagggcaac cgcttccccg
    19441 acgtctacct ggacgactgg ctgggcccgt gggaccggct cggcgagctg cgcaagccgg
    19501 tggtggcggc ggtggccggc ttcgcgctgg gcggcggctg cgagctggcg atgctctgcg
    19561 acatcctgct cgccgcggac accgcgaagt tcgggcagcc ggagatcaag ctcggcgtca
    19621 tccccggcat cggcggctcg cagcggctga cccgcgcggt cggcaaggcg aaggcgatgg
    19681 agctctgcct gaccggccgg atgatgggcg ccgaggaggc cgagcgggcc ggcctggtct
    19741 cccggatcgt cccggccgac cagctgctcg ccgaggcgct ggccgtcgcc gagaaggtcg
    19801 ccgcgatgtc gaccccggcc gccatcatgc tgaaggagag cgtgaaccgc tccttcgaga
    19861 ccaccctcgc cgagggcgtc cgcttcgaac gccgcctgtt ccacgccgcg ttcgcgacgg
    19921 ccgaccagaa ggagggcatg gccgccttcg ccgagaagcg cccggcctcc ttcacccacc
    19981 gctgaccggt cacgggtagc ggacggcggc cggcaggctt ctcggctgcc gtccgccatc
    20041 cgttcgccgt ccgccatccg ttcgccggag ccgcccacgg ccggggccgc cgggcgccgg
    20101 ccgtcccccg gccgtggccg ctcccggtcc gccgcacccc ggcccgcccg tcagtcctcg
    20161 ctcaccagcg ccgtgttgag ccgggccaga ccgctgcggg tcgcggccac cacgatccgg
    20221 tcgccgggcg cgagggcgcg ggtgcggtcg gggtagctcc accggtaggt gtgcgggctg
    20281 ccggccaggc ggacggcgac cacgcggacg ccgcccgggt cctccaggtc gtggcggttc
    20341 atcccgacca ggccgccgcc gtcctcggcc cgcagttcgg cgatcagcag cacgtgccgg
    20401 aacaccgaca gcgtgcccag cacctcgcgc cccatcaggg cggcggcgaa ggcgggcgcg
    20461 gccaggtagg acgtcgaccg ggaggcggcg ttgtccagcg tcgcgtagac gtggcgggcg
    20521 aagttgtcgt cgaagaggcg gagcaccacc cgcacgtcgg gccggccggc gcgggcctcc
    20581 agcgcggcct ccaggttggt ggcgtcgtcc ccgctgaccg cgaccaccgc ccggctgtgc
    20641 ttcagccggg cccggcgcag ctgttccgcc agcgggccgt cgtcgacgac caccggcacg
    20701 ccgagtgcgc ggaccgcgga gatgccgcgg gcctgcgggt cccgctccag gcccaccacc
    20761 ggcacgccca gaccgtggag ttgggcgacg acgcgggtgc cgacgttgcc caggccggcc
    20821 acgatgacgt ggtcccgggt gcccgccccg gggttgcggg gctggccgcg ccgcccggag
    20881 ccgagcacct cgaccatgat ggcggtggcg accggcgcga aggtgatgcc gcagaaggtg
    20941 atcaccacct gggcgacccg ttgccagagg ccgccggtgc cggtgcccgc ggccgcgtcg
    21001 gagggctggt cgggctgggc cgcgccggcc aggtcgagca gcgcgacgta gagcgaccag
    21061 ccgaagtccc ggttgaggta ccagagcact ccgaaggcca tcagcaccgc cgcgagcgcg
    21121 gtgatcagca ccagccggag ccgggcgctg gtgaagaagc gcagggtgtc gagcagccgc
    21181 cagcgcagtc ggcgcgtcca ggagatccgg accggtggtt cgctgggcag ggtctgcagt
    21241 gcggc
//
