LOCUS       NZ_CP012673            22045 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Sorangium cellulosum strain So ce26 chromosome, complete genome.
ACCESSION   NZ_CP012673
VERSION     NZ_CP012673.1
KEYWORDS    RefSeq.
SOURCE      Sorangium cellulosum
  ORGANISM  Sorangium cellulosum
            Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae;
            Sorangium.
REFERENCE   1  (bases 1 to 14557589)
  AUTHORS   Zaburannyi,N., Bunk,B., Overmann,J. and Mueller,R.
  TITLE     Sorangium comparison
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 14557589)
  AUTHORS   Zaburannyi,N., Bunk,B., Overmann,J. and Mueller,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-SEP-2015) Department of Microbial Natural Products
            (MINS), Helmholtz Institute for Pharmaceutical Research Saarland
            (HIPS), Campus E 8.1, Saarbruecken, Saarland 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SMRT portal v. 2.2.0, HGAP v. 3.0
            Genome Coverage                   :: 134x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002950945.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 11:58:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,531
            CDSs (total)                      :: 10,457
            Genes (coding)                    :: 10,397
            CDSs (with protein)               :: 10,397
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 6 of 60
            Pseudo Genes (incomplete)         :: 58 of 60
            Pseudo Genes (internal stop)      :: 2 of 60
            Pseudo Genes (multiple problems)  :: 6 of 60
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:39:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10146749
            Orig. end                         :: 10168794
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012673.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from German Collection of Microorganisms and
            Cell Cultures GmbH, Inhoffenstrasse 7B, 38124 Braunschweig,
            Germany.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22045
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="thioamitides"
                     /region_number="33"
                     /rules="((YcaO or TIGR03604) and TfuA)"
                     /tool="antismash"
     cand_cluster    1..22045
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and TfuA)"
                     /kind="single"
                     /product="thioamitides"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22045
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12045](+)"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12045
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
     misc_feature    complement(438..451)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.2"
                     /tool="antismash"
     gene            617..1726
                     /locus_tag="SOCE26_RS36740"
                     /old_locus_tag="SOCE26_073900"
     CDS             617..1726
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020740217.1"
                     /locus_tag="SOCE26_RS36740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073900"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_104984204.1"
                     /transl_table=11
                     /translation="MGNPSSISSSFELFRRLARRLGVPARHAEDVAQDALLRGLEADQR
                     IAPGGDLAAYRITIAMNQAHDHVRTARRRGEVLTSFDESEVRAEYPNPEDVLRGRQRHA
                     LVRRLIDRLDPKYRDLVRKHDLDEVPLARIAAELGLTTEAVKTQHRRALEELKAEQRRW
                     IAEEHGRGRDGDACVPVAFGLYRRESWLATLRRLVFRILVQGALVILTGALVSGASHSL
                     EAWLLPAAARAPGSAPATQEVAPTREGSASAAAESAAPAAREGALPAHRDRAGALAAVD
                     SRPAASAEPPPPGAVPGGVVRRNAAPGSAVPPAISERERRLIRDARRALDAHNALADLE
                     ARQLLEMHKQEFPQGWLALERERLLSQLR"
     misc_feature    1811..1822
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     gene            1846..2235
                     /locus_tag="SOCE26_RS36745"
                     /old_locus_tag="SOCE26_073910"
     CDS             1846..2235
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SOCE26_RS36745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SOCE26_073910"
                     /product="hypothetical protein"
                     /protein_id="WP_234022772.1"
                     /transl_table=11
                     /translation="MEDILGAMWLASPIGLAMMACVAIGFAVTAREALGRERGLREAGE
                     QRHEDEDEESALADAKEDAERGLRRCRRLLDCHVDALIAAMTSPRARPVPLPGRVLETF
                     CATIPGWQRKLAESTGLGPRDWSGC"
     gene            2441..2776
                     /locus_tag="SOCE26_RS36750"
                     /old_locus_tag="SOCE26_073920"
     CDS             2441..2776
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SOCE26_RS36750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SOCE26_073920"
                     /product="hypothetical protein"
                     /protein_id="WP_104984205.1"
                     /transl_table=11
                     /translation="MVTKRQPKHELGLPKGALVTRHKVHRRKVRLMNGRTIGLVFHETW
                     TRNLLRIPDCVTDRHLRELGRAGLELATDIFGNPIAKAPGAPWFNGADFEIARWRFILR
                     QKLRRRR"
     misc_feature    2645..2647
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3618..5423
                     /locus_tag="SOCE26_RS36760"
                     /old_locus_tag="SOCE26_073940"
     CDS             3618..5423
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008134 - transcription factor binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025885.4"
                     /locus_tag="SOCE26_RS36760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073940"
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="WP_159397655.1"
                     /transl_table=11
                     /translation="MDDQRHDDGRNDTSTEKLPGGADGPPARPRPRGVSVLFFHRGGVE
                     AMRLDPGQPGMVVGRRAPADLYIPDKRISHLHARFTLVGDHVLVEDLDSTNGTWVKGER
                     ITAPTMLAPGADAILGDVSAHVVAIGLIATPAVLDEATFHRELDAECTRAQCLRRSFAV
                     LAVHPGEAEAAHAKTGEWAIHLPANLRPVDRVSMWRDTALILVPEADTKDAIKIGHAVA
                     SGGGNQSGVRRVGVAVYRENGSSPQKLIDEACSAADLATAERPVFVASPNCTAALDDRP
                     IFGLAQQRVVTEAKKAASTNLSVLLLGESGTGKEVLARFIHDHSTRRDKPFMPVNCGAI
                     PGNLIESTFFGHEKGAFTGAVQQKQGFFQAAHEGTLFLDEIGELEPEAQKRLLRVLEAR
                     TVSPVGSTKEIPVDVRIIAATNRNIDAMLKEGSFREDLYYRLDISLRIPPLRDRLDEIE
                     QLVHRFIQEERTSVRDITPEAMALLCAYRWPGNVRELRREIRRAVAMAEGELIQPEDLS
                     SHLHLADPQAAVADNATAAPSRSDPEKPPAGPDLRSQLAQLERQRIETALREEKTKPKA
                     AARLGISPRTLSRKITELGIRPPKR"
     gene            5719..9204
                     /locus_tag="SOCE26_RS36765"
                     /old_locus_tag="SOCE26_073950"
     CDS             5719..9204
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="SOCE26_RS36765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073950"
                     /product="protein kinase"
                     /protein_id="WP_159397656.1"
                     /sec_met_domain="Pkinase (E-value: 3.8e-45, bitscore:
                     153.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEQGTASDAPDEPRQLGPYRIIERLGEGGMGVVFRAAHVLTGE
                     EVAIKTVRRVNDADHLAAIRRETRVLRRLNHPGIVRFLDENVTGGVPWVAMPLLGGGTL
                     RDRIAATFPKDAGMGAAITVPAQASGSVPASVRLRTDEPGASADARPLGSMLTLIRRLC
                     APLAYLHGEGLVHRDLKPANIVLQDDGRPVLVDLGIAVHFGGAGREELDVDPLAGSLAY
                     TAPEQLQREPVDARADLYALGCILYECVTGRPPFLGNTSSLCEQHRSAPPQRPSALVTS
                     LPAALDDLILALLAKNPQHRVQYAADVATKLVALGAAAERDEGPAPRVYLYRPVLAGRT
                     DAVCKLQVMAQRAAFERRGAIALVRGESGSGKTRLVREVSRAVKAKGLPLQVFSGVCVA
                     PGAGEAGATAAMAAPLQPLRTTLLDAVDRARDSEEQADRLFGGRREVLAAYVPELRALR
                     SPSEPVPLPPSQARKRVVSALRETLRALAEARPLCLLLDDLQWADDLTLALLDAFARAE
                     PDERGGVLIIGTYRIEETRPELEDIAHVPGATSIRLDKLAARDIEDMVVGMLSPSMPPR
                     TVLDALIRNANGNPFFVAEYLRAALDAGELQRDHVGSFSFKGRGAAALASLQIPDTLDE
                     LLGRRLDLLEAEARELAAWAAVLGQELDDELLFAGPRGQDAATDAVAELRARRILEETE
                     TGQLRFVHDKLREKVYSRLDPGARAELHRRAGEALEARGAEAPVLAHHFAGAGLHGKAG
                     AHFARAAQRAAEVYANRDAVRFYRLTIDALSTAGAAPAALADLHEGLGDVLGLVGRQAE
                     ARDAYGAALDAATSRVDHARLHRKVGKTWEMHHQHARALECYGQAETALGEQTERTSGE
                     AQAWWNEWIQIHLDRISVQYWLADLARLNALVETVRPVLEHRGTPLHRAHYLHALTQWG
                     IQRDRFVASAETLRYADECVAAYQAASAPPEGHLALAARCSLAIVRMLYGDPDQAEAEM
                     RDALPIAERSGDLEVMTRCLTYLTVIQRRRSLVEGAESLAKRTLKLAKAENVREYAGAA
                     LGNLAWCALQRGDLARAEEAGQEALACWEPLPLVYPFQWLARLPLCRVEFARGRLEGAI
                     AQARAVLDPRQQRLPGRLTKLLETAARAFAAGREARACRPLALALRGAHHSGYA"
     gene            9331..9981
                     /locus_tag="SOCE26_RS36770"
                     /old_locus_tag="SOCE26_073960"
     CDS             9331..9981
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SOCE26_RS36770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SOCE26_073960"
                     /product="hypothetical protein"
                     /protein_id="WP_104984209.1"
                     /transl_table=11
                     /translation="MSNEIPCINDRRGIVFTINRESNPVYQLESGAWASAENRWAERDI
                     PPEIRDKVASLKETGKPGSFVQFLQGDVGVYVICERNIKNLPEMACDDLVVQGTRTKLG
                     SARELADYDLVIYAKGGAIRAESGETFETREGDYYVVHCQSWGRFVLNASLRPGFVETT
                     KEVLLLLEGLHRKNFLSMSPDPTDERLPPDFGEPTAVPVGINCYVLNLSRFKR"
     gene            10001..11275
                     /locus_tag="SOCE26_RS36775"
                     /old_locus_tag="SOCE26_073970"
     CDS             10001..11275
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012239732.1"
                     /locus_tag="SOCE26_RS36775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073970"
                     /product="YcaO-like family protein"
                     /protein_id="WP_104984210.1"
                     /sec_met_domain="YcaO (E-value: 2.2e-79, bitscore: 266.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSTNPARAEQRSGPPPPAPKRYLAGTHRLVSADETVERVRPLL
                     PAMGITRIADVTGLDTLGVPVVMVTRPNARSIAVSQGKGSTLAAARASGVMESIEQWHA
                     EHIQLPLKLGTVSELRHRHRLLDVHNLPRLSVVDFHDHLRLFWVAGLDLATGAPTWVPF
                     EVVHTDYALPLLAASGAFVMSSNGLASGNHPIEAVSHAMCELIERDAATLWKLSSREQR
                     RRTRIDLSTVDDPGCRALLEQVENAGVIPFLWEITSDVGVPAFCCTLVDRAPNLHRPIA
                     PMVGFGCHPSRDVALLRAITEAAQSRLTVITGVRDDVRARGNGPDDDLRAASRFLEEHA
                     GEPPQRSFDDAPDHAGETLDDDVAWEIERLRTVGLHQIVAVDLTRPELEIPVVRVVIPG
                     LEPLDDVPGYIPGARAQRRLSERRS"
     gene            11272..12045
                     /locus_tag="SOCE26_RS36780"
                     /old_locus_tag="SOCE26_073980"
     CDS             11272..12045
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF019429.4"
                     /locus_tag="SOCE26_RS36780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073980"
                     /product="TfuA-like protein"
                     /protein_id="WP_199789409.1"
                     /sec_met_domain="TfuA (E-value: 2.5e-47, bitscore: 158.7,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLCIFTGPTLPAAEGQQQIDAIFLPPAAQGDIYRAALERPVAIG
                     LIDGYFERVPSVSHKEILWAMAQGVHVLGASSMGALRATELSLFGMEGVGAIYEAYASG
                     ALDADDEVAVAHASAEDGYRPLSEAMVNLRATLRAAEGAGVISGSTRERLEELSRGLFY
                     PDRCYPILLRRAAQEGLPPAQIEALRAFLPEGRVDQKRADALALLQVLRERFEGGSKPK
                     QVRYHFEPTDAWELIRDHADRRASTSNRSTREAGR"
     gene            12042..12953
                     /locus_tag="SOCE26_RS36785"
                     /old_locus_tag="SOCE26_073990"
     CDS             12042..12953
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SOCE26_RS36785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SOCE26_073990"
                     /product="hypothetical protein"
                     /protein_id="WP_104984211.1"
                     /transl_table=11
                     /translation="MSPSERANLSRLGQYIVVRLLCKHDGYSARDIAKTLKAVLKDRGS
                     DAEQQRLVEAELTTLTRAGLIKGVRKSSFMNTPSGWRAALGAIARKDLPPKPVWKDLKE
                     QLDNCVNARIVKTLTGAFRLAVAPEPTLQQVIDALLWHVIKVETSEPFTAEAVTRVLLN
                     RLAGTPTLLPVDQALDELVAKASAPPLNAPSVPSGAPVPAGAALPADDTAFAARVLAAA
                     RSSKTGRFGDDKVFISHVFQRLADQGDAVGDPDAFKARLVSAHRRGLLSLNRADLVEAM
                     DPADVDASETRYLSATFHFVRI"
     gene            13025..16270
                     /locus_tag="SOCE26_RS36790"
                     /old_locus_tag="SOCE26_074000"
     CDS             13025..16270
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="SOCE26_RS36790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_074000"
                     /product="helicase HerA-like domain-containing protein"
                     /protein_id="WP_104984212.1"
                     /transl_table=11
                     /translation="MTKQDALLDVFLSAAKKDVFHSVEHRGQIWREDPFDVESVHEQAR
                     TQFQRLLTQVTTPPGLDAGRILLLLGESGSGKTHLVRAFRNHVHMNGLGFVGYMQMTTS
                     VSSYSRYLVSNLIDSLDQTYYEALGTGSGLLRLSNAVAARCGDPDAIRSVSEREDLDAD
                     QVIDLVERAADRLIAHPRYADLDLDLVRALLFLQRQDPALKKRVIKYLRCEVLSERDQK
                     LLGGLSPKRDEEDAQRLVEQLGRLMWACDSRALVLCVDQFEDAYRVNEAEALFRRVMSS
                     LCAIADQVPSSIIVVACLKDYYGMMRARLTRSTLDRIESDPPPVRLIAERQLDEIEQII
                     EQRLGYLYETSDCRPAEGAIDPLYPVPRDFVQQLSGLSIRTVLTECHKFREACIEAGRI
                     VASPGEGSPSSVKQAAPAEHGVRALKEKIEQEWNDFLAQYQEDLAEDDAEIAELFGWAV
                     KTCAEEFESGIQFAVRVRGKTIEVDVLVPTQGGGHCVREEILVVLCNRAPQGGGLRAQF
                     EEARQRAERRTLALLRCGEFPRNPRAQVHITLADILKNGGRKAVLEESDQRTLAAFRKF
                     RETHEGRDHFTAWLREENHLSRLLPLIHALNLDHLDRFNHEPASEESTAPRAPGAGAST
                     FESQPAPEGDEPRGATPARAQPGVHADAVTIHLGTTGELVSQELTLEAEALTSHAAFLG
                     STGSGKTTLALNLIEQLLLHGIPAVLVDRKGDLSGYAREPLWTRRPPDPALDARRRALR
                     ERVDVALFTPGHPGGRQLALSLVPRGFAGLQDLDRDQAAGYAAQALGDMLGYKQTRKDK
                     GLRAILVQAFQLFAAHGASDRLDIESLITLIANEDPALVSALGRLDTRLFKDLVHDLEV
                     LKLSSADILSTAGEQLDAELLFGLGPHARPGRTRLSVVSTKFLGDNTRILFWVSQLLLA
                     LSRWVTRAPSPRLQAVVLFDEADVYLPSQSQPATKAPMENLLRRARAGGLGLLLATQSP
                     GDLDYKCRDNLRSWFVGRVTQGVAIEKMKPLLSDARVDVTARIPGQGPGEFHLLQEGRV
                     TAFKGRMPLLQAEQVSESEILKLAARRRREGAG"
     misc_feature    13610..13612
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16337..19981
                     /locus_tag="SOCE26_RS36795"
                     /old_locus_tag="SOCE26_074010"
     CDS             16337..19981
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1173: WD-40
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="SOCE26_RS36795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_074010"
                     /product="AAA family ATPase"
                     /protein_id="WP_104984213.1"
                     /transl_table=11
                     /translation="MSGAIIDFEEERSRHEQLFGREDVLETLLGWLIGEQALLPGGWVF
                     LLGSPGVGKSAIVNRLLDLLPPDTPHHFIRRHTDDWDRPEALVNNLVARVERLFAEPAN
                     ADLPLEARLGELLRRVSKRKLIPNGRRLVLVIDGLDEAASDNAGRNLLPRFLPRVVPSG
                     VAILCASRPMYPHADWIAGFDGVHSILDLDEGEWAASNETACRTYCVQRLRRLSPPLNN
                     ADIETVVRNAQGNMVYARWICEWLAGQPPARRTTTNIFQGLSGLIRQIVSELRGLDGAR
                     RALILQGLGLTCATREALPAYVFNELLGGGPTASEGDEFLRATFHLLRNEPAQWHKGQK
                     GYRLYHEHVREVLIEMLGDRAMRDHHFQILRTIAVWPPDEQDQSRRRYALRHAVAHLIE
                     AGDVSGAQRLCADIRYLDAKCRELDVHSIERDLEAVIGASEGEAAFELTALLAAVRAEA
                     SRLSAHRSHGLLPSLLYNRLRCGGWLAERIERMLCFGGDLPPLRLLHGVRLGPTPLRTF
                     CDHTKPVVACVVSRDGRYALSASADRTLRFWALLSGEVLATMRGHEDELTDCALTPDGR
                     TAVSTSIDMTARLWDVATGECIGVLLNSDRGATACAISPDGPLLVVGSDDGLLTLWDLS
                     SRQRVAVLAGHSDYVTACLMTRAGQLVSASRDRTVRVWDLASRTCVYVLSSEDDTCLPA
                     PRGSEQGWITALALLPGGEQILAAAGDGALSRWDLASGERLQCIGAGQGRVDALAILPW
                     GSHLLCGMADGAIAVWDLAVERCVLRLAAHANAVSACASTPDGRRIVSASHDRSARLWE
                     LGGPESLVFQDGHTAPVTAIATTADRRLVVSASEDRLLKIWDTATGACRIILEGHAAVV
                     TACAISGDSRRVLAGALDGSVLLFHLDHDRGQARVEIATGHRTHVSGCALLPDGRMVTA
                     SKDGSLWIRGPGTLDNAVELGTHDGPIAGVAITPDGSRLLSISRDGTAKLWDLTAGRRA
                     PTRVRLAGELLACSLTPDGGRAVLAFADGQIELRELHGWKCVRRIPAHEQRIFGCAVSP
                     DGARVISASEDGTVRAFSLETGRHLSTLIGTSWFRCVAAAPALICAGDQEGNVWMIVDG
                     FATPGARSRDQGARRQGAPSAEAIALVRDRLAWLFDSEAAARLVVKDARLDERRINLIG
                     SALERWGRILDEAIKQGRLIDVVRCALGRYPHDDVLLELAEKLGISGH"
     misc_feature    20013..20028
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     gene            20032..21024
                     /locus_tag="SOCE26_RS36800"
                     /old_locus_tag="SOCE26_074020"
     CDS             20032..21024
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024758.4"
                     /locus_tag="SOCE26_RS36800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_074020"
                     /product="trypsin-like peptidase domain-containing protein"
                     /protein_id="WP_104984214.1"
                     /transl_table=11
                     /translation="MTDELLSPDAIGTLREALSWKYPTDAEARRFVADVRLDPRRITFH
                     GRADLTWFSILEEAQKRGASSVRAVLDRATKEYPEDEVLARLRDGAAVRYAEGPSIAAV
                     PWRGSGGPPLEKILGTQSSLVPVSYLEIGIRRAQAVARIQVSDGSLGTGFLIPGDLLVT
                     NHHVLGDRGAAADAIAQFNFQKTVDGRDAEPEKLCFDPDAFFVTSSDDDCTIVKVAGEP
                     SARWGTIALQPARIELGERINIIQHPGGDQKQLSFFHNLVVYVGEGRVQYLTDTLPGSS
                     GSPVFNKHWELVALHHSGGWLLEPGTKDRFFRNEGIHVDRVVDVLRRCR"
     misc_feature    21506..21521
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
ORIGIN
        1 gctgactcgg cagcgcccaa tctcgctcaa gactccaggt caggtgctcc gctgcgtcgc
       61 ggtacttgcg cagctcgagc tcacagaggc cgagctcgcc ggcgagctct gcgggatcga
      121 acgccccgcg gtcgagctcc gcgcggtcga gcttcatggc gggcggcagg ttggcggcat
      181 cgagggccgc cttgaaggcg tcgcaggcct ccgtccagtt gccacgatcg cgcgctttcc
      241 gagcacggcg aacaaggtcc tttaccgtcg cgccgtcgct gctccccggg gccggagacc
      301 gctgctgagc atcggccgag ctgggcaagc ccgttgaagc gccaagcgtg agcaaaacga
      361 acaacaggtg cgcaccgcaa cgcatgcaac gacggtactt acgccgcgcg cgcgacgtca
      421 accgggagaa aacgctgcaa acagcgcttt ggtcgagaat ttacggacgg atggcggaat
      481 ggatccatcc ggtgtgtcgg tgatcttgtg gcccaccgcg gcgaaccgtg gcatgttatc
      541 ctacactgtg cgccgaaagt gatggcggcc gtgcattttg ctgaccccga gggggtcgct
      601 cagacgtgct accagcgtgg gcaacccgtc gagtatttcc agcagcttcg agctcttccg
      661 gcgcctcgcg aggcgcctcg gcgttccggc acgtcatgcc gaggacgtgg cgcaagacgc
      721 gctcctgcgc gggctggagg cggaccagcg gatcgcgccg ggcggagacc tggcggcgta
      781 ccgcatcacg atcgcgatga accaagcgca cgaccacgtg cggaccgcgc gccgtcgggg
      841 agaggtcctg acgtcgttcg acgagagcga agtccgagcc gagtacccga atccagaaga
      901 cgtgctccgg gggcgccagc ggcatgcgct cgtgcgccgc ctgatcgacc ggctcgaccc
      961 gaagtaccgg gatttggtgc gcaagcacga cctcgatgag gtcccgctcg cccggatcgc
     1021 cgccgagctg ggccttacga cggaggcggt gaagacgcag caccgccggg ccctcgagga
     1081 gctgaaagcg gagcagcgcc gctggatcgc cgaggagcat gggcgcggac gggacggcga
     1141 cgcgtgcgtc ccggtggcgt tcggcctcta ccgtcgcgag tcgtggctgg ccactctgcg
     1201 gcgcctggtc ttcaggatct tggtgcaggg cgcgctcgtc atcctgacgg gcgcgctggt
     1261 ctctggggcg tcgcacagct tggaagcctg gctgttgccc gcggcggctc gcgcgcccgg
     1321 ctccgcgcct gccacgcagg aggtcgcgcc tacccgagaa ggcagcgcga gcgccgccgc
     1381 agagagcgct gcgccagccg cgcgcgaggg tgcgctgccc gcgcatcgag accgcgcggg
     1441 cgccctggcc gccgtggaca gcaggcccgc ggcgtcggcc gagcctcccc ctcctggcgc
     1501 ggtgcccggg ggcgtcgtgc gccgaaacgc ggcgcccggg agcgccgtgc ccccggccat
     1561 cagcgagcgc gagcgccggc tgatccgtga cgcccgccgc gcgctggacg cccacaacgc
     1621 cctcgccgac ctcgaggcgc gccagctgct cgagatgcac aagcaggagt tcccgcaagg
     1681 gtggctcgcc ttggagcgcg aacggctgct cagccagctt cgctgattca tcggctgtcg
     1741 atcgacagct agcgggcggc ggcgccggtg atgctttcgg gcagcacaag gccgagatcc
     1801 gccttgcgtc ggacacgaac gctcacgtcc aggaggcaac atacgatgga ggacattctg
     1861 ggtgcgatgt ggctcgcttc gccgatcggt ctcgcgatga tggcctgtgt cgcgatcggc
     1921 ttcgcggtga cggcgcgcga agcgctgggc cgcgaacgtg ggctgcgcga ggcaggcgag
     1981 cagaggcacg aggacgagga cgaggagtcg gccctcgccg acgcgaagga ggacgcggag
     2041 cgcgggctgc ggcgatgccg gcgcctgctg gactgccacg tggatgcgct catcgcggcg
     2101 atgaccagcc cacgcgcgcg ccccgtgccg ttgccaggcc gcgtcctcga gacgttctgc
     2161 gcgaccatcc ccggctggca acggaagcta gccgagagca ccgggctggg gccgagggac
     2221 tggagcggct gctgaagagc gatctcccga tctcgcccgt cctcgcgagg cagctggagg
     2281 ccttcacggg cacacctgct cggtactggg agttcctctg gcggcagcat gagcccctct
     2341 ccgaggatgc gcggcggcac gggacgagcc cgcacaccgc gatcagcacg ccccggatcg
     2401 cacgcgcgac gctcatgctc tcgctcagga ggtggcgccg atggtgacga agcgccagcc
     2461 gaagcacgag ctcggccttc ccaagggggc ccttgtcacg cgccacaagg tccaccgccg
     2521 gaaggtgcgc ctcatgaacg gccggaccat cggcctggtg ttccacgaga cgtggacccg
     2581 gaacctgctc cggatcccgg actgcgtgac cgatcgccac cttcgcgagc tcgggcgcgc
     2641 ggggttagag ctcgccacgg acatcttcgg caacccgatc gcgaaggcgc ccggcgcgcc
     2701 ctggttcaac ggcgccgact tcgagatcgc acgctggcgc ttcatcctgc ggcagaagct
     2761 ccggaggcgc cgatgagcgc ccgagccgag aagcggtgcg tgccgaccgc ggaacccctc
     2821 tcctacatcg ccgagcggtc gcgcaccctc gccatctacg cctccggcgg aatgtcgtcg
     2881 ccaagaatga gcgccacgtc ctaccgcgcg cggcggtctc gctggacagg ccgatcctcg
     2941 acctgagcga ggccgcggcc tacgttgacc gccgcagacc cccgcgcgtg gctctgggcg
     3001 ccagctgacg catcccgagg cgggcgtgga cggcgcgagc ggcggcgagc tggccggccg
     3061 cgaggagccc gcggagttcc tcggagaggg ccgccacggg cgtgttggaa ccgaccgggc
     3121 cgcgcccggt ccgcgtcagt gcctcagggg gttcgcgctg gtagatgcgc cggccgcgcc
     3181 cgagaggatc ctcggcgacc acgtgccggc gacagcgtcg ccggcgccct cgccttctcc
     3241 ttcaccgggg cgcttcggcg gtagagacgt gccggctccc ggcccgcaca gcgccgtggt
     3301 gctgccgaga aagcgatccg ctcaccggac cggacgcgtc gcgccatgac gctggcgggc
     3361 tcggcagatc cgtgcgggtc gcccggcgtt tgagcctgcg gcttccccgg cagctcgtcc
     3421 acccactccg ccgggtccga gcgggagtgc cgttcgcggg ctccatgtcg aagctgcgcg
     3481 gaggattcct gttgcagcgg aggacagggt aggcagagca tcaccgccgg aggcgagcgc
     3541 ggcggggcag cccatcgggc atgctgagca tcgacgtcgg gcgggttgcg cctctaatct
     3601 tcgcgagggg aacagccatg gacgaccagc ggcacgacga cggacggaac gacacgagca
     3661 ccgagaagct cccgggcggc gcggacgggc cgcccgcacg accgcggccg cgcggcgtct
     3721 ccgtcttgtt ctttcatcgc ggcggtgtcg aagcgatgcg gctcgaccct ggtcagccgg
     3781 ggatggtcgt cggccggcgc gcgcccgcag acctgtacat ccccgacaag cgaatttccc
     3841 accttcacgc gcggttcacg ctcgtcggcg accacgtcct cgtcgaggat ctcgactcca
     3901 ccaacggcac ctgggtgaag ggcgagcgga tcaccgcgcc caccatgctc gcaccaggcg
     3961 ccgacgccat tctgggagac gtcagcgctc acgttgtcgc gatcggcctc atcgccacgc
     4021 cggccgtgct ggacgaggcg acctttcatc gggagctcga tgcggagtgc acgcgtgcgc
     4081 agtgcttgcg ccgaagcttc gcagtcctcg cagttcaccc cggtgaggcg gaggccgcgc
     4141 acgcgaagac tggggagtgg gccatacacc taccggcgaa tctacggcct gtcgatcgcg
     4201 tgagcatgtg gagggatacc gcgctgatcc tggtccccga ggcggacacg aaggatgcca
     4261 tcaaaatagg gcacgcggtc gcgtccggcg gcggcaacca gagcggcgtt cgccgcgtcg
     4321 gtgtggccgt gtaccgggaa aacggaagct cgccccagaa gctcattgat gaagcgtgca
     4381 gcgcggcgga cctcgcgacc gcagagcgcc ccgtgttcgt cgcctcgccc aattgcaccg
     4441 cagcgctcga cgatcgcccc atcttcggtc tggcccagca acgggtcgtc accgaagcga
     4501 agaaggcggc ctcgacgaac ctctctgtac tgctcctggg agaaagcggc acaggcaagg
     4561 aggtgttggc gcgctttatt catgaccata gcacacgacg agacaagccg ttcatgcccg
     4621 tcaactgcgg cgctattccc ggcaacctca tcgagagcac gttcttcggc catgaaaaag
     4681 gcgcctttac cggcgccgtt cagcagaagc agggcttctt ccaggctgct cacgaaggca
     4741 cgttgttcct cgacgaaatc ggcgagctcg agcctgaagc acaaaagagg cttctccggg
     4801 tgctcgaggc acgcacggtc tctcccgtgg gctcgaccaa ggagataccc gtcgacgtgc
     4861 ggatcatcgc agcaaccaac cgcaatattg acgccatgct caaggaaggc agctttcgcg
     4921 aggatctcta ctaccggctg gacatctcgc tgcggatccc tcctctccgc gatcgcctcg
     4981 acgagattga acagctcgta catcgcttca tccaggagga acggactagc gtacgcgaca
     5041 tcaccccgga ggcgatggcc ctgctctgcg cttaccgatg gccgggaaac gtgcgtgagc
     5101 tccgccgcga gatccgccgg gcggtcgcga tggccgaggg ggagctgatt caacctgagg
     5161 atctctcgtc gcatctgcat ctagcggacc cgcaggcggc agtcgccgac aatgctacgg
     5221 cagccccgtc tcggtcggac ccagagaagc cgccagcggg ccccgacctc aggtcacagt
     5281 tggcgcagct cgagcggcaa agaatcgaga cggcgctccg ggaggaaaag accaagccca
     5341 aggccgccgc acggctcgga atttcacccc gtacgctctc acgcaagatc acggagctcg
     5401 gcatcaggcc cccgaagcga taggccaagg ttgaccacca gcgggccaac cttggcctgc
     5461 ccgtggtcaa ccttggcctg cgcgccgcgc agcggctgag caacggtgcg gatttccgcg
     5521 gggatccgcg acacgcctgg ctcggcacgc aacgtgctgg gtgtccgcga cgtgagcgcg
     5581 aagggcgaag gcagcacgac gatgccgcag aggagacctg agggggaacg cctccagggg
     5641 ctcgcgcctg ccgctcggtc tcccgggagg ataggacgcc aggccgacgt cgaagctgcg
     5701 gtagcctcct gctctccgat gatcgacgag cagggaacag ccagcgacgc gccggacgag
     5761 cctcgccagc tcggcccgta ccggatcatc gaacgcctcg gcgaaggcgg catgggcgtc
     5821 gtcttccgcg ccgcacacgt cctgacaggc gaggaagtgg ccatcaagac ggtgcgccgc
     5881 gtgaacgacg ccgaccacct cgccgcgata cgccgtgaga cgcgggtgct ccgccgcttg
     5941 aaccaccctg gcatcgttcg cttcctcgac gagaatgtca ccggcggagt gccctgggtc
     6001 gcgatgccgc tcctcggggg cggcacgctc cgggatcgca tcgcggctac gtttccgaaa
     6061 gacgccggca tgggcgcggc gatcaccgtt cccgcgcaag cctcggggtc cgttccggcc
     6121 agcgtccgcc tgcgcaccga cgagcctgga gcgagcgcgg acgcgcgccc gctcggctcg
     6181 atgctcacgc tgatccgtcg cctttgcgcg ccgctcgcct acctgcatgg cgagggcttg
     6241 gtgcaccgcg acctcaagcc cgcgaacatc gtcctccagg acgacggacg ccctgtgctc
     6301 gtcgaccttg ggatcgccgt tcacttcggc ggcgccggcc gcgaggagct cgacgtggat
     6361 ccgctcgccg gcagtttggc ctacacggcc ccggagcagc tccagcggga accggtcgac
     6421 gcgcgcgccg atctctacgc gctcggctgc atcctctacg agtgcgtgac gggacgacct
     6481 cccttccttg gcaatacctc gtccctttgc gagcagcacc gctccgcccc gcctcagcgc
     6541 ccctcggctc ttgtcacaag cctccccgca gcactcgacg acctcatcct cgcgctcctg
     6601 gcgaagaatc cacagcatcg agtccagtac gccgccgacg tagccacgaa gctcgtcgcg
     6661 ttgggcgcgg cggccgagcg cgacgagggc ccagcgccac gcgtgtactt gtaccggccc
     6721 gtgctcgcag gccgcaccga tgccgtttgc aagctgcagg tgatggccca gcgcgccgcc
     6781 ttcgagcggc gaggcgccat cgcgctcgta cgcggggaga gcggctcggg taagacgcgg
     6841 ctcgtccggg aggtgagccg cgctgtcaag gcgaaggggc tgccgctcca ggtgttctcg
     6901 ggcgtgtgcg ttgcgcctgg ggccggcgag gcgggtgcga cggcggcgat ggccgccccg
     6961 ctgcaaccgc tgcgcacgac gctcttggac gcggtcgatc gagcgcgcga ctccgaggag
     7021 caagcagacc ggctcttcgg cgggcgccgg gaggtgctcg cggcctacgt gccagagctg
     7081 cgagcgctcc ggagcccgtc ggagccggtg cccctgccgc cctcgcaggc gcggaagcgc
     7141 gtcgtctccg cgctgcgaga gacccttcgg gcgcttgccg aggcgaggcc gctctgtctt
     7201 ctcctggacg acctgcagtg ggccgatgat ctcaccctgg ccctgctcga tgcgtttgcc
     7261 cgagccgagc ccgacgagcg cggtggcgtg ctgatcatcg gcacctaccg gatcgaggag
     7321 acgcgcccgg agctcgagga tatcgcgcac gtccccgggg ccacatcgat ccggctcgac
     7381 aagctggccg ctcgcgacat cgaggacatg gtcgtgggca tgctctcgcc gagcatgcca
     7441 ccccggactg tgctcgacgc gctcatccgc aacgcgaacg gcaacccttt cttcgtcgcc
     7501 gagtacctgc gcgcggccct cgacgcagga gaactccagc gggaccacgt cggcagcttc
     7561 tcttttaagg ggcgcggcgc cgcggcgctc gcgtccctcc agatcccgga cacgctggac
     7621 gagctcctcg gacggcggct cgacctgctc gaggcagagg cgcgggagct cgcggcgtgg
     7681 gcggcggtgc tggggcagga gctcgacgac gagctcctct tcgcgggccc gcgcgggcaa
     7741 gacgcggcga ccgacgcggt tgcggagctc cgggcgcggc gaatcctcga ggagacggag
     7801 acgggacagc tgcgcttcgt gcacgacaag ctccgcgaaa aagtctacag ccggctcgac
     7861 ccgggagcgc gggccgagct gcaccggcgc gctggcgagg cgctcgaggc gcgcggcgcc
     7921 gaggcgccgg tgctcgcgca ccacttcgcg ggagcaggcc tccacggcaa ggccggcgcg
     7981 cacttcgcgc gggctgcgca gcgcgccgcc gaggtctatg cgaaccgcga cgccgtccgc
     8041 ttctaccgcc tgaccatcga cgccctctcg accgctggcg ccgctcccgc agcgctcgcc
     8101 gatctgcacg aagggctggg ggacgtgctc gggctcgtcg ggcgtcaagc agaggcccgc
     8161 gatgcctacg gcgcggcgct cgatgcggcg acttcccgcg tcgaccacgc tcggctccac
     8221 cgcaaggtcg gcaagacctg ggagatgcac caccagcacg ccagggcgct cgagtgctac
     8281 gggcaggcgg agaccgccct cggtgagcag accgagcgaa cctcgggcga ggcccaggcg
     8341 tggtggaacg agtggatcca gatccatctg gatcgcatct ccgtgcagta ctggctcgcc
     8401 gatctcgccc ggctgaacgc gctcgtcgag accgtccgcc ccgtgctgga gcacaggggt
     8461 acaccgctgc accgcgccca ctacctccac gcgctgacgc agtggggcat ccagcgcgat
     8521 cggttcgtcg cgtccgccga gacgctgcgc tacgccgacg agtgcgtcgc ggcgtaccag
     8581 gctgcgagcg cgccgcccga aggccacttg gcactggccg cgcgctgcag cctcgcgatc
     8641 gtccgcatgc tgtacggcga ccccgaccag gccgaagccg agatgcgcga cgcgcttccg
     8701 atcgcggagc ggagcggcga cctggaggtg atgacgcgat gcctgaccta tctcacagtc
     8761 atccagcgca ggcggagcct cgtcgagggt gcggagagcc tggccaagcg cacattgaag
     8821 ctggcgaagg ctgagaacgt gcgcgagtac gccggagccg ccctgggcaa cctcgcgtgg
     8881 tgcgcgctcc agcgcggcga cctcgcgcgg gccgaggagg ccggccagga agcgctcgcc
     8941 tgctgggagc cgctccccct ggtctacccc ttccagtggc tggcccggct gccgctctgc
     9001 cgggtggaat tcgcgcgtgg tcgcctggag ggcgccatcg cgcaggcacg tgcggtcctc
     9061 gacccacggc agcagcgctt gccgggtcgg ctcaccaagc tactcgagac ggcagctcgc
     9121 gcgttcgcgg caggccgcga ggcccgcgct tgccggccgc tcgcgctggc gctccgcggc
     9181 gcccaccaca gcggatacgc gtgagctgat cctcgactca accgatcttc ttaacggcgc
     9241 gccgaggccc gccgcgcggc ccccgtccgc gcccggtccg cgcgcgccgc gtgtggaatt
     9301 gcgatgacga aacgagaacg gagctgagcc atgtccaacg agatcccgtg catcaatgat
     9361 cgaagaggca ttgtcttcac catcaatcgg gagtcgaacc ccgtttacca gctggagtcg
     9421 ggcgcgtggg cgagcgcgga gaaccgctgg gccgagcgcg atatcccgcc cgagatccgc
     9481 gataaggtcg cctccctcaa ggagaccggc aagcctggat cattcgtgca gtttctccag
     9541 ggcgacgtcg gggtctatgt catctgtgag aggaacatca agaacctccc cgagatggca
     9601 tgcgacgatc tcgtcgtcca ggggacgcgc acgaagcttg gcagcgcgcg ggagctcgcc
     9661 gactacgatc tggtcattta cgccaagggc ggcgcgatac gcgcagagag cggcgaaacc
     9721 ttcgagaccc gtgaaggcga ctactacgtc gtccactgcc agtcgtgggg ccgcttcgtc
     9781 ctgaatgcct ccctgagacc cgggttcgtc gagacgacca aggaggtctt gctcctgctc
     9841 gagggcctgc accgcaagaa cttcctctcc atgagccccg atcccacgga cgagcggttg
     9901 cccccggact tcggggagcc cacagccgtc cccgtcggga tcaactgcta cgtcctcaac
     9961 ctgtcgcgct ttaagcgctg agcggagcgc gaggatgtcc atgagcacct ccacgaaccc
    10021 cgcccgcgcc gagcagcgat cgggccctcc gccgcccgca cccaagcggt atctcgcggg
    10081 cacccaccgc ctcgtctctg ccgatgagac ggtggagcgg gtccggcccc tcttgcccgc
    10141 gatgggcatc acccggatcg ccgacgtcac cggcctcgac accctcggcg tgccggtggt
    10201 catggtcacc cgaccgaacg cgcgctcgat cgcggtctcg caaggcaagg gctcgaccct
    10261 ggccgccgcg cgcgcctcgg gtgtgatgga gtccatcgag caatggcacg ccgagcacat
    10321 ccagctcccg ctcaagctcg gcaccgtcag cgaactccgc caccgccacc gcctccttga
    10381 cgtccacaac ctgccgcgcc tgtccgtcgt cgacttccat gatcatctcc gcctgttctg
    10441 ggtggctggc ctggatctcg cgacgggcgc gcccacctgg gttccgttcg aggtcgtcca
    10501 cacggattat gcgctgccgt tgctcgccgc gagcggagcc ttcgtgatga gctcgaacgg
    10561 gctcgcctcc ggcaaccacc cgatcgaggc ggtgagccac gctatgtgcg agctcatcga
    10621 aagggatgcc gccacgctct ggaagctctc gagtcgggaa cagcggcgcc gcacgcggat
    10681 cgacctgtcc acggtggacg acccgggatg ccgcgcgctc ctggagcagg tggaaaacgc
    10741 cggcgtcatc cccttcctct gggagatcac atccgatgtc ggcgtcccgg ccttctgctg
    10801 cacgctcgtc gaccgcgcgc ccaacctgca ccggcccatc gcgccgatgg tcggcttcgg
    10861 ttgccacccc tcccgagatg tggcgcttct gcgcgcgatc accgaggcag cgcaaagccg
    10921 gctcaccgtc atcaccggtg tgcgcgacga tgtccgggcc cgcggcaacg ggcccgacga
    10981 cgatctccgc gcggcgagcc gcttcctgga ggagcacgcc ggcgagccgc ctcagcgcag
    11041 cttcgacgac gcgcccgatc atgcgggcga aaccctcgac gacgacgtcg cctgggagat
    11101 cgagcgcctg cgcaccgtgg gccttcacca gatcgtcgct gtcgacctca cccggcccga
    11161 gctcgaaatc ccggtggtgc gcgtggtcat cccgggcctc gagccgctcg acgatgtccc
    11221 cggctacatc cccggcgcgc gcgcgcagcg gcgcctttcg gagcgcagat catgaccctc
    11281 tgcatcttca caggtcccac cctcccggct gcggagggcc agcagcagat cgacgccatc
    11341 ttcctgccgc ccgcggccca gggcgacatc taccgcgcgg cgctggagag acccgtcgcc
    11401 atcggcctca tcgacggcta cttcgagcgg gttccgtccg tgtcccacaa ggagatcctc
    11461 tgggcgatgg cgcaaggagt ccacgtcctc ggcgcatcaa gcatgggggc gctccgcgcg
    11521 accgaactct cgctcttcgg catggagggg gtgggcgcca tctacgaagc ctacgcgagc
    11581 ggcgcgctgg acgcggacga cgaggtggcg gtggcccacg cgtccgcgga ggatggttat
    11641 cgccccctca gtgaggcgat ggtgaacctc cgcgccaccc tgcgcgccgc cgagggggcc
    11701 ggcgtgatct cgggttcgac acgcgagcgc ctggaagagc tgtcccgagg cctgttctac
    11761 ccggatcggt gctatccgat cctcctccgg cgcgcggcgc aggaaggcct cccgcctgct
    11821 cagatcgagg cgctgcgggc gtttctgccc gagggtcggg tcgaccagaa gcgcgccgac
    11881 gcactcgcat tgctccaggt tcttcgcgag cgcttcgagg gcgggagcaa accgaagcag
    11941 gtgcgttatc acttcgagcc gaccgacgcg tgggagctca tccgcgacca cgcggatcgc
    12001 cgcgcgtcca cgtcgaaccg cagcacgagg gaggccggac gatgagcccc agcgagagag
    12061 ccaatctcag ccgtctcggc cagtacatcg tcgtccggct gctctgcaag cacgatggct
    12121 actcggcgcg cgacatcgcc aagacgctga aggccgttct gaaggatcga ggaagcgatg
    12181 ccgagcagca gcggctcgtc gaagccgagc tcaccacgct cacgcgcgct ggcctcatca
    12241 agggtgtgag gaaatcgtcc ttcatgaata cccccagcgg atggcgcgcg gcgctcggcg
    12301 ccatcgcgag gaaggatctt ccccccaagc cagtctggaa agatctcaaa gagcaactcg
    12361 ataattgcgt caatgcgcgt atcgtcaaga ccttgacggg cgcgtttcga ctcgccgtcg
    12421 ctcctgaacc aacgcttcag caggtcatcg acgctctctt gtggcatgtc atcaaggtcg
    12481 agaccagcga gcccttcacc gcggaagcgg tcacccgcgt gctcctcaac cggctggccg
    12541 gcacgccgac gctgctcccc gtggaccagg cgctcgatga gctcgtggcc aaggcctcgg
    12601 cccctcccct gaacgcgccc tccgttccat caggggcccc ggtgcccgcg ggcgcggcgc
    12661 tgcccgcgga tgacacggcg ttcgccgcgc gcgtgctcgc cgccgcgcgg tcgtcgaaga
    12721 ccgggcggtt tggagatgac aaggtgttca tctcacacgt cttccagcgg ctcgccgacc
    12781 agggtgacgc ggtcggagat ccggacgcgt tcaaggcccg gttggtctcc gcccatcggc
    12841 gcggactctt gtcgctcaat cgcgccgacc tggtagaagc catggatcca gcagacgtcg
    12901 acgcatcgga gaccagatat ctaagcgcga cgttccactt cgtgcgcatc tgacatcggg
    12961 cgccagcggc gcgcgaggcg cgaggcgcgc gccgccgacg agcaactgga tgaaggggtg
    13021 aaccatgacg aagcaggacg ccctgctcga cgtgttcctg tcggcagcga agaaagacgt
    13081 gttccactcg gtggagcacc gtgggcagat ctggcgggag gacccgttcg acgtggagtc
    13141 cgtgcacgag caggcgcgca cgcagttcca gcgtctgctc acgcaggtga cgaccccgcc
    13201 aggcctcgat gcagggcgga tcctgctgct cctcggcgag tcgggcagcg gcaagacgca
    13261 cctcgtacgc gccttccgca accacgttca catgaatgga ctcggcttcg tcggctacat
    13321 gcagatgacg acgtcggtct ccagctacag ccgctacctg gttagcaatc tgatcgactc
    13381 actcgatcag acctactacg aggcgctcgg aaccggctcg gggctgctcc gcctatccaa
    13441 cgctgtcgcg gcccggtgcg gcgatccgga cgccatccgc tccgtgagcg agcgcgagga
    13501 cctcgatgcg gatcaggtca tcgatctcgt ggagcgcgcg gccgatcggc tcatcgcgca
    13561 tccccgctac gccgatctcg atctggacct agtccgcgcc ctgctcttct tacagcggca
    13621 ggatccggcg ctgaagaagc gggtcatcaa atacctgcgg tgcgaggtgc tctcggagcg
    13681 ggaccagaag ctcctcggcg gattgtcgcc gaagcgcgac gaggaggacg ctcagcggct
    13741 cgtcgagcag ctcggtcgct tgatgtgggc ctgcgactcc cgcgccctgg tcctctgcgt
    13801 cgatcagttc gaggacgcct atcgggtcaa cgaggccgag gcgctgttcc gccgggtgat
    13861 gtcctctctc tgcgccatcg ccgatcaggt tccctcgtcc atcattgtgg tcgcctgcct
    13921 caaggattac tacgggatga tgcgcgcccg gctcacccga tcgacgctcg accgcatcga
    13981 gagcgaccct ccgccggtcc gcctcatcgc cgagcggcag ctcgacgaga tcgagcagat
    14041 catcgagcag cggctcggtt acctctacga gacgtccgac tgccggccgg cagagggcgc
    14101 aatcgacccc ctctaccccg tcccgcggga ctttgtgcag cagctctccg gactcagcat
    14161 ccggacggtg ctcactgagt gccacaagtt ccgggaagca tgtatcgagg ccggccggat
    14221 cgtggcctcg cccggagagg gctcgcccag cagcgtgaag caggccgcgc ctgcggagca
    14281 cggcgtccgc gccttgaagg agaagatcga gcaagagtgg aacgactttt tggcgcagta
    14341 ccaggaagac ctggccgagg acgacgccga gattgccgag ctcttcggat gggcggtcaa
    14401 aacgtgcgcc gaggagttcg aaagcggcat ccagttcgcc gttcgggtcc gcggcaagac
    14461 gatcgaggtc gacgtcctcg tccccacgca gggcggcggc cattgcgtcc gcgaggagat
    14521 ccttgtcgtg ctctgcaacc gggcgcccca gggcggcggg ctccgcgcgc agttcgagga
    14581 agcgcgccag cgcgccgagc gccggaccct cgccctgctc cgctgcggcg agtttccacg
    14641 caacccgagg gcgcaagtac acatcacgct cgcggacatc ctcaagaacg ggggacgtaa
    14701 ggcggtcctg gaagagagcg accagcgcac gctcgccgcg ttccgcaagt tccgcgagac
    14761 gcacgagggg cgtgatcact tcacggcctg gctccgtgag gaaaatcacc tctcccggct
    14821 cctgccgctc atccatgctc tcaacctcga tcacctcgac cgcttcaatc acgagccggc
    14881 gtccgaggaa tccacggcgc cgcgcgcacc tggcgccggc gcctcgacgt tcgagtcgca
    14941 gcctgctccg gagggcgacg agcctcgcgg cgctacaccg gcgcgcgcgc agcctggcgt
    15001 ccatgccgat gccgtcacga tccacctcgg gacgaccggc gagctcgtct ctcaagagct
    15061 cacgctcgaa gccgaggcgc tcacgtccca tgccgccttc ctcggcagca ccgggagcgg
    15121 caagaccacg ctggcgctaa acctcatcga gcagctgctc ctccacggca tccccgccgt
    15181 cctcgtggat cgcaagggcg atctctccgg ctacgcgcgc gagcctctct ggactcgacg
    15241 gcccccggac ccggcgctcg atgcgcgacg ccgtgcgctc cgcgagcgag tcgacgtcgc
    15301 cctcttcacc ccgggccacc ccggcggtcg ccagctcgca ctctcgctgg ttccgcgagg
    15361 gttcgccggt ctccaggatc tcgatcgcga tcaggcagct ggttacgcgg cacaggccct
    15421 cggcgacatg ctcggttaca agcaaacaag gaaagacaag gggctccgcg cgatcctcgt
    15481 ccaggccttt cagctcttcg ccgcgcacgg ggcgtcggac aggctcgaca tcgagtcgct
    15541 gattaccctc atcgctaatg aggatccagc gctcgtctcc gcgctaggcc ggctcgatac
    15601 ccggctgttc aaggacctcg tgcacgacct cgaggtgctc aagctgagct ccgcggacat
    15661 cctgtccacg gccggcgagc agctcgacgc cgagctactc ttcggcctcg gcccgcacgc
    15721 ccggcccggg cgcacgcggc tcagcgtcgt cagcacgaag ttcctgggcg acaacacgcg
    15781 gatcctgttc tgggtctcgc agctcctgct cgcgctgagc cgctgggtga cgcgcgcccc
    15841 atccccgcgc ctgcaagccg tcgtgctctt cgacgaggcg gacgtgtact tgccgtctca
    15901 gtcacagccg gccacgaaag cgcccatgga gaacctcctc cggcgcgcgc gcgccggagg
    15961 cctcggcctg ctgctcgcga ctcagagtcc gggggatctc gattacaagt gccgagacaa
    16021 cctgcggagc tggttcgtcg gtcgcgtgac gcagggggtg gcgatcgaga agatgaagcc
    16081 gctgctgagc gatgcccggg tcgacgtgac ggcgcgaatc cccgggcagg ggccaggtga
    16141 gttccacctg ctccaggaag gacgcgtgac agccttcaag gggcgtatgc cgctgctgca
    16201 ggccgagcag gtgtcggaga gcgagatcct gaagctcgcg gcgcgaaggc ggcgcgaagg
    16261 cgccggatga gccagtggcc gcccatgaga cgcaagggtt ctgtcgttcg catccatcga
    16321 cgcgaggagt gacacggtga gcggcgcgat catcgatttc gaggaagagc ggtcgcggca
    16381 tgagcagctc ttcgggcgcg aggacgtact cgagacgctc ctcgggtggc tgatcggcga
    16441 gcaggcgctg cttccgggtg gctgggtgtt cctcttgggg agccccggcg tcggcaagag
    16501 cgccatcgtc aaccggctcc tcgatctgtt gcccccggac acaccgcatc acttcatccg
    16561 ccggcacacg gacgactggg atcgtcccga ggcgctggtg aacaacctcg tcgctcgggt
    16621 agagcggttg ttcgcagagc cggccaacgc cgatctaccc ctggaggcac gcctgggcga
    16681 gctgctccgg cgggtgtcga agcgaaagct catcccgaac ggtcggcggc tcgtcctcgt
    16741 aattgacggg ctggacgagg cggcgagcga caacgcggga agaaacctcc tgccgcgctt
    16801 cctgccgcgc gtcgtgccct ccggcgtagc gatcctgtgc gcctcacggc cgatgtaccc
    16861 tcacgccgat tggatcgcag ggttcgacgg cgtgcacagc atcctagacc tggacgaggg
    16921 cgagtgggct gcctccaacg agacggcctg caggacctac tgcgtgcagc gcctgcgccg
    16981 cctgtctccg ccgctcaaca acgctgacat cgagaccgtg gtgcgcaacg cgcaggggaa
    17041 tatggtctac gcgcgatgga tctgcgaatg gctcgccggg cagccacctg cgcggcgcac
    17101 caccacgaat atcttccagg gcctatccgg tctaatccga caaatcgtgt ctgagctccg
    17161 agggctcgac ggggcgcggc gtgcgctcat cctccagggc ctcggcctga cctgcgccac
    17221 gcgcgaggcg ctgcctgcat atgtcttcaa cgagctgctc gggggcggcc cgacggcgag
    17281 cgagggagat gaatttctgc gagcgacgtt ccacttgttg cggaacgagc cggcgcaatg
    17341 gcacaagggc cagaaaggtt atcggctgta ccacgagcac gtacgcgagg tcctcatcga
    17401 gatgctcggc gatcgggcga tgcgcgatca ccacttccag atcctccgaa cgatcgcggt
    17461 ctggccaccc gacgagcagg atcagtcccg acggcgttac gcgctccgtc atgcggtagc
    17521 acacctgatc gaggccggcg acgtgagcgg cgcacagcgc ctttgcgctg atatccgcta
    17581 tctcgacgcc aagtgccgcg agctcgacgt ccactccatc gagcgagatc tcgaggcagt
    17641 gatcggcgct tcggaaggag aggcggcctt cgagctgacg gcgctgctcg ccgccgtgcg
    17701 cgcggaggca agccggctct ctgcccaccg gagccacggg ctcctcccgt cgcttctcta
    17761 caatcgccta cgctgcggag ggtggctcgc cgaacggatc gagcgaatgc tctgcttcgg
    17821 cggggacctg cctccgctga gattgcttca cggggtgcgg ctcgggccga caccgctgcg
    17881 caccttctgt gaccacacga aaccggtcgt cgcatgcgtc gtctcgcggg atgggcgtta
    17941 cgccctgtcg gcatcagccg accgcacgct ccgcttctgg gctctcctct cgggcgaggt
    18001 gctcgcgacg atgcggggac acgaagatga gctcacggat tgcgcgctca cgccggacgg
    18061 ccggaccgcc gtatcgacat ccatcgacat gacggcgcgg ctctgggatg tcgccacagg
    18121 cgagtgcatc ggtgtactcc tcaatagcga tcgcggcgcg accgcctgcg ccatcagccc
    18181 ggacggcccg ctgctcgtgg tcggctcgga cgacggcctc ctgacgctct gggatctcag
    18241 ctctcgccag cgcgtcgccg tgctggcggg acacagcgat tacgtgaccg cgtgcctgat
    18301 gacccgcgcg ggtcagctcg tctccgcgtc gcgggaccgc acggtgcgcg tctgggatct
    18361 cgcttcccgc acctgcgtgt atgtgctctc ctccgaggac gacacctgct tgcccgcgcc
    18421 acgcgggtcg gagcaggggt ggatcactgc cctcgcgctc cttccgggag gcgagcagat
    18481 cctcgctgca gcgggagacg gcgcgctctc gcgctgggat ctcgcctccg gtgaacgcct
    18541 ccagtgcatc ggcgctggac agggccgcgt ggacgcgctc gcgatcctcc cctggggtag
    18601 ccacctgctc tgcgggatgg cggacggcgc gatcgcggtc tgggacctcg ccgtcgagcg
    18661 ctgcgtcctg cgactggcgg cgcatgccaa cgcggtgtcg gcgtgcgcgt cgaccccgga
    18721 cggtcgacgc attgtctccg cttcacatga ccgttcggcc aggctgtggg aactcggggg
    18781 tccggagagc ttggtgttcc aggacggtca caccgccccg gtgaccgcga tcgcgaccac
    18841 cgccgaccgg cgcctagtcg tctcggcttc ggaagaccgg ctcctcaaga tctgggatac
    18901 cgcgaccggc gcgtgccgca tcatcctcga ggggcacgcc gctgtggtga cggcgtgcgc
    18961 tatctctggg gacagccggc gcgtgctcgc tggtgcgctc gacgggagcg tgctcctgtt
    19021 ccacctcgac cacgatcgcg gacaggcccg cgtggagatc gccaccggcc accggacgca
    19081 cgtgagcggc tgcgcgctcc tccccgacgg acggatggtc accgcctcga aggatggatc
    19141 gctgtggatc cgtggcccgg ggactctcga caacgccgta gagctaggca cgcacgacgg
    19201 accgatcgcc ggcgttgcga tcacccccga tggctcgcgg ctcctgtcga tctctcgcga
    19261 cgggaccgcg aagctctggg atctcaccgc cggccgccgc gcgccgacgc gggtccgcct
    19321 tgctggggag ctcctcgcat gctccctcac ccccgatggc ggacgcgctg tgctcgcctt
    19381 tgctgacggc cagatagagc tacgcgagct ccacggctgg aagtgcgtgc gcaggatccc
    19441 agcgcatgag cagcgaatct tcggctgcgc ggtgtcgccg gacggagcgc gcgtcatctc
    19501 agcatccgag gacgggacgg tacgagcgtt cagcctggag accggacggc acctgagcac
    19561 gctgatcggg acctcttggt tccggtgcgt tgccgcggct cccgcgctga tctgtgcggg
    19621 cgatcaggag ggtaatgtct ggatgatcgt ggacgggttc gccactcccg gcgcacgctc
    19681 gcgcgatcag ggcgcgcgcc ggcaaggcgc cccatcagca gaggccattg cgctggtgcg
    19741 cgacaggctg gcctggctct tcgattccga ggcggctgcg cggctcgtcg tcaaggatgc
    19801 acgactcgac gagcggcgca tcaacctcat cgggagcgcg ctcgagcgat ggggccgcat
    19861 cctcgatgaa gcgatcaagc aaggtcgcct catcgacgtg gtgcgttgcg ctctcggacg
    19921 ctacccccac gatgacgttc tcctcgagct ggcagagaag ctcgggattt caggacactg
    19981 acacggtgcg cgcagccatc gagctggctc actgcgatgg aggtcacaca aatgacggat
    20041 gagcttcttt caccagacgc cataggaact ctccgggagg ccctctcgtg gaagtacccg
    20101 accgacgcgg aggcgcgccg gtttgtggcc gacgtgcggc tcgacccgag acgcatcacc
    20161 ttccacggcc gggccgatct cacatggttc agcatcctcg aagaggcaca aaagcggggc
    20221 gcatcgtcgg tacgcgcagt gctcgaccgc gccaccaagg agtatccgga ggacgaagtg
    20281 ctcgcgcgtc tgcgcgacgg ggccgcggtg cgctacgccg aagggccgag catcgccgcc
    20341 gtcccgtggc ggggtagcgg cggtccgccg ctcgagaaga tcctcggcac gcagagctcg
    20401 ctcgtccccg tgagctacct cgagatcggc atccgccgcg ctcaggcggt cgcgcgcatc
    20461 caggtctccg acggctcgct cggaacgggc tttctcatcc cgggtgacct cctggtcacc
    20521 aatcaccacg tcctcggtga ccgaggcgcc gctgccgacg caatcgccca gttcaacttc
    20581 caaaagacgg tcgacggccg cgacgcggaa ccggagaagt tgtgcttcga ccccgacgcc
    20641 ttcttcgtta cttccagcga cgacgactgc acgatcgtca aggtcgcggg cgagccctcc
    20701 gcacgctggg ggacgatcgc gctccagcct gccaggatcg aactcggcga acggatcaac
    20761 atcatccagc accccggcgg tgaccagaag cagctctcgt tcttccacaa cctggttgtt
    20821 tacgtgggcg agggccgcgt gcagtacctg accgacacgc tgcctggctc atccggctcg
    20881 cccgtcttca acaagcactg ggagctcgtc gcgctgcatc acagcggcgg atggctcctc
    20941 gagccaggaa ccaaggaccg cttcttccgc aacgaaggga tccatgtcga tcgggtggtg
    21001 gatgtgctcc gcaggtgccg ctgagatacg gagctcatta cctgccgaca aaggtgagcg
    21061 agcatcctca acgggcaatc tccaataagt ctcgcaaccg ttccgtcttt cggaggtgca
    21121 cgatggtgaa tcgagtgatc cttctctcgg ggcctgtagc gtccggcaag acgacgctca
    21181 gcgatgcgct ggtgaaccgg taccggttca agcggctcaa gacccgcgat ctcatccacg
    21241 cgatggcggg gacggcggca gagcgagggg cgctccagga cgccggagag cggctggatc
    21301 gcgagactgg cgggctgtgg gtcgccgagg cgctgaccag gtcggtttcg cagctcgggg
    21361 agaacgtgac ggtagtcgtg gacgcggtgc gagtcgaggc tcaagttgac gccatccgaa
    21421 gggcgttcgg cctccgtacg acccacgtgc acctcacggc ctccgacggc attctcgcgc
    21481 agcggtaccg ggaccgaaac cgtgcggtga aagagttcac atcatacgag gaggtgcgcg
    21541 ccaacgcgac agagagcggg atcgaaaagc tcaaatatat cgcagatatc gtgatcgaca
    21601 ccgcgcgaag ctctcctgag gacgtcttcg tccgcgtcgc gagccacctc gggctctacg
    21661 gccgaggcgt cgagcaggtc gtcgacgtga tcgtgggcgg tcagtacggt agtgagggca
    21721 aggggcacat cgcgtcgtat ctcgcgcccg agtacgatct cctcgtccgg gtcggcggac
    21781 cgaatgcagg gcacacggtg tacgaggagc cggagccgta cactttccac ctcctcccct
    21841 cgggcacccg gcgctccgag gcgaagctcg tgctcggtcc cggcgccacc ctcgacgtgg
    21901 atactctgcg caaggagatc gcggactgcc gggtgccaca gggccggctt ttcatcgatc
    21961 cgcaggccat ggtcattgag gcggccgaca tcacgttcga ggcagagaag ctcaccggct
    22021 cgatcggctc gaccggacga ggcgt
//
