LOCUS       NZ_CP012673            10873 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Sorangium cellulosum strain So ce26 chromosome, complete genome.
ACCESSION   NZ_CP012673
VERSION     NZ_CP012673.1
KEYWORDS    RefSeq.
SOURCE      Sorangium cellulosum
  ORGANISM  Sorangium cellulosum
            Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae;
            Sorangium.
REFERENCE   1  (bases 1 to 14557589)
  AUTHORS   Zaburannyi,N., Bunk,B., Overmann,J. and Mueller,R.
  TITLE     Sorangium comparison
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 14557589)
  AUTHORS   Zaburannyi,N., Bunk,B., Overmann,J. and Mueller,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-SEP-2015) Department of Microbial Natural Products
            (MINS), Helmholtz Institute for Pharmaceutical Research Saarland
            (HIPS), Campus E 8.1, Saarbruecken, Saarland 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SMRT portal v. 2.2.0, HGAP v. 3.0
            Genome Coverage                   :: 134x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002950945.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 11:58:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,531
            CDSs (total)                      :: 10,457
            Genes (coding)                    :: 10,397
            CDSs (with protein)               :: 10,397
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 6 of 60
            Pseudo Genes (incomplete)         :: 58 of 60
            Pseudo Genes (internal stop)      :: 2 of 60
            Pseudo Genes (multiple problems)  :: 6 of 60
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:39:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10093511
            Orig. end                         :: 10104384
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012673.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from German Collection of Microorganisms and
            Cell Cultures GmbH, Inhoffenstrasse 7B, 38124 Braunschweig,
            Germany.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10873
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="32"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10873
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10873
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5873](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5873
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(567..581)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.32"
                     /tool="antismash"
     gene            1268..1525
                     /locus_tag="SOCE26_RS36520"
                     /old_locus_tag="SOCE26_073450"
     CDS             1268..1525
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SOCE26_RS36520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SOCE26_073450"
                     /product="hypothetical protein"
                     /protein_id="WP_104984171.1"
                     /transl_table=11
                     /translation="MGNERSKDQLGVERPEREVSEEKQPHPQAEVPGVRGAITSSGERA
                     DAPEDEVETFGSEGGAGNYKGGPEYSNKEIPPESSGGKPA"
     gene            complement(2035..2415)
                     /locus_tag="SOCE26_RS36525"
                     /old_locus_tag="SOCE26_073460"
     CDS             complement(2035..2415)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020739068.1"
                     /locus_tag="SOCE26_RS36525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073460"
                     /product="hypothetical protein"
                     /protein_id="WP_104984172.1"
                     /transl_table=11
                     /translation="MNARSSSPRRGVFFFTGLAIALASSAACTPPQAAQGTTATTGTAA
                     AGREGDDCSTGALLTCPEGQVDGCAIGTTTQHRCVEAGPGGCLDIRAALVKCKESEVLT
                     HEGCPEPAYMQRCAPRPAQQQQ"
     gene            complement(2562..3194)
                     /locus_tag="SOCE26_RS36530"
                     /old_locus_tag="SOCE26_073470"
     CDS             complement(2562..3194)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012238678.1"
                     /locus_tag="SOCE26_RS36530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073470"
                     /product="hypothetical protein"
                     /protein_id="WP_234022762.1"
                     /transl_table=11
                     /translation="MKMRRLAAAAMAVAAMMALAFAADAQDTAADRGGRPAGNVPPADQ
                     PLIERLPEPTIAVEGGFGMLGYLGGTAAVGPTWNVRVTGTLSPRLAVEGNYIGSVNERT
                     TAGRSLVMTSFDAGVRYNVLRAHEAIVQPFVVAGVGYVGWAGEGGDAFALSVPLTAGVE
                     RLVTRNIKLGARFNFRPAFLDDLSVRGAAEQTGGDSWAVIAHGGGAF"
     gene            3581..4414
                     /locus_tag="SOCE26_RS36535"
                     /old_locus_tag="SOCE26_073480"
     CDS             3581..4414
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020739070.1"
                     /locus_tag="SOCE26_RS36535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073480"
                     /product="YceI family protein"
                     /protein_id="WP_104984173.1"
                     /transl_table=11
                     /translation="MTTIRTRTLLLAALAATGVSAAACQEEKAPLAPAATELKAPAAKV
                     PAAATFAIDRANSKVELIMDAPQEKIRGRIEGAAEGTLHVDPADVTRTTGLITIDISPL
                     ELLQTGMGDDGKPGQEKKSDLQNEHARTWLEISKDTPADVREKNTRAQFAIKSISTSGE
                     KDLSKLSGAERSVTVTASGDLLLHQRQAPKTVELVATFTYEGDRLARVAVKTAKPFAVG
                     LAEHDVRPREAFGKLAQKTLEVLSPKVAKEAMVSLEFTATPVKNDAAAPAPDAAR"
     gene            4571..4978
                     /locus_tag="SOCE26_RS36540"
                     /old_locus_tag="SOCE26_073490"
     CDS             4571..4978
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020739071.1"
                     /locus_tag="SOCE26_RS36540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073490"
                     /product="hypothetical protein"
                     /protein_id="WP_104984174.1"
                     /transl_table=11
                     /translation="MLSKKSIYETLAALSAGAMVVSGCGGAQAPVNAAEVPAEHETAPA
                     APTEATSGDDAAGATTPATPAEPSSTTEAPTPAPPTDVQSAATAPQVAPTATPAPAAPA
                     PPSPTTPAKPTAKKPAGKKPGHAGCGAGTCG"
     gene            5001..5873
                     /locus_tag="SOCE26_RS36545"
                     /old_locus_tag="SOCE26_073500"
     CDS             5001..5873
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012238681.1"
                     /locus_tag="SOCE26_RS36545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073500"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_104984175.1"
                     /sec_met_domain="DUF692 (E-value: 2.4e-94, bitscore: 314.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPTTGSAPTGVGLGLRWEFLEEVLAALDEGAALPVPFFELSPEN
                     YMRRGGYYPAAIERIRERRPILTHGLTLSVGGIDPFDAGYLRALGDLLGRLDPPFHSDH
                     LCFCGVDGRLLHDLLPLPLTPAAAAHAAARIREVEDRLERPMAVENITSYLVPGRASLD
                     EADFLVEVLERAGCGLLLDVNNLYVNARNHGFDPVAFLEKIPPRRVVAMHVAGHEWRDE
                     AEVLVDTHGAPVIEPVLDLLARAVARTGPVPVVLERDHDVPPLAALLDELAAVDAAYRR
                     GLAAREAQA"
     gene            5870..6796
                     /locus_tag="SOCE26_RS36550"
                     /old_locus_tag="SOCE26_073510"
     CDS             5870..6796
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012238682.1"
                     /locus_tag="SOCE26_RS36550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073510"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_104984176.1"
                     /transl_table=11
                     /translation="MSRAGGAGGGRPGDAGGASGGRPGGAGGQPAPAPPELAALQRALQ
                     RSVSEPDGAAIAADPRAWLARAGLDGPDLDAMASLPPKRLLLYRSLVRSGLTSAIRNEI
                     PRTAARLGALFEAYVSRFLAEELPRSPYLRDVAFEFVAFAAPRWAADPEVPSYLADLAR
                     HELAAFVAACAEPEGAAAGAPGSGDELSLDRGARFQRAATLVRYEHAVHRLQGGEAARD
                     VPAREPVSLLVYRDAEHEVRYLELTPLAAEILGRLLEGETLRDAVVAGCAALGRPVDGP
                     VLESTAAFLSDLAERGALLGASPQSTT"
     gene            6906..8156
                     /locus_tag="SOCE26_RS36555"
                     /old_locus_tag="SOCE26_073520"
     CDS             6906..8156
                     /EC_number="3.1.1.-"
                     /GO_function="GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012238685.1"
                     /locus_tag="SOCE26_RS36555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073520"
                     /product="lactonase family protein"
                     /protein_id="WP_104984177.1"
                     /transl_table=11
                     /translation="MQRTLFWLAAGLWLGCGSSGAGTPKNGASTGASGGGGPVSPNGNA
                     GGGGNAGGGGGRGSAGGGASAPGRGPFVYVGGHAGIFVFRLSEADGALDAVEGPLDAEM
                     NPTFLAVDPTHRHLFAVNELSEVDGEASGAVSAFQIGQEDGKLAFLNRISSKGKGPAHL
                     AADRSGRFILVTNYGGGTAAVLPIGPGGELGQAVAERTFGLRSRSHHAVTDPANRFAFV
                     TNLGLDAIAQLTFDEATGQLGASDPPAITFPRGTTPRHLEFHPNGRFAYVINESAGSIT
                     TLRYDPARGTFSAVATVSTLPQGVSREDNTCAEIQVSPSGKFVYGSNRGHDSIAIFAVD
                     PERGTLTPVGHQPTGGATPRHFQLSPAGKLLLVANQDSDNLVAFHVNEATGALDPTGRV
                     TAVPEPTYVGIVHLTAR"
     gene            8382..10628
                     /locus_tag="SOCE26_RS36560"
                     /old_locus_tag="SOCE26_073530"
     CDS             8382..10628
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="SOCE26_RS36560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_073530"
                     /product="bifunctional serine/threonine-protein
                     kinase/formylglycine-generating enzyme family protein"
                     /protein_id="WP_104984178.1"
                     /sec_met_domain="Pkinase (E-value: 6.8e-28, bitscore: 97.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQNLDRSDPLTIAGTLIADKYRIERAVGEGGFSVVYKAEHIIWK
                     QPVALKCFTLLANAPADQREQLLQGFIQEGKLMAELSSRSAAIVQARDVGTFNAPDGQW
                     LPYMVLEWLDGMPLDRVFEEEARQGLPRRDLYATLALLESAAVALELVHSRNIAHRDIK
                     PANLFVIGRPRDPSAFVKVLDFGIAKVMAEHAAAATALAQTGKEITAFTPSYGAPEQFS
                     RIHGATGPWTDVFAMALIMVEVMLGGAPALQGDDYMQLAVASRDPARRPTPRTLGLEVS
                     NEVEAVFEKALAVAPSDRFPTMGRFWSALHRATSLDDPSWAMSPGGGSLAPPSGAAPPR
                     ASSPRMSSSPRMSSSPHMSWPQVAPTMAAPPTAPAPGTVPPATSQTAVLQEMSTTGGTA
                     NDAATQRSAPAAPRSKGALVLGGAAVVLAAGGAIAVQLLREPAEPPQADTSRTAPIASS
                     APPIASASAPAVPAARPTECPSGMVLVPGGKFFMGSDDPAFKLWQPAHKVTIDTFCIDV
                     HEVTAGEYKACSDKGECKRPPAAPDFPRPDGVSAAEHERTLAALAELCTFGEPELAQHP
                     INCVPWSLADAYCGVQGKRLPTEAEWEYAARGSDGRKFPWGDEPGDHTFMNACGAECTK
                     WETARKLKPSPRMYDADDGFFGTAPVGSFPKGKTRFGAHDTVGNVWEWTADWFATYKDE
                     ELVNPKGAPAGDRKAIRGGGYNGGFPLWMNPAFRYHQLATASAPGIGFRCVTDL"
ORIGIN
        1 gacgacgcgg cggctcacgg tgaagcacgc ggacccggag gaggtccggc gggcgcgggc
       61 gctcttccgg gagctggagc tgctccccgg gctgaacgcg ctggcggagc aggtcctctg
      121 cggcgggcgg cccgagctcg tccgggacct cgcgcacccg ctgctcgcct cgctgagcca
      181 gcagggcgcc ttgcgccggg tcgtccggga gctcggggtg acgtcggcgg tgatggtccc
      241 gctggtcgcg cgggggcgga ccttcggctg catcacgctg gcgaccgcgg ggtctggccg
      301 ggtgtacgac gaggtggacc tcgcgctcgc gcacgatctg gcgcagcggg ccgcgctcgc
      361 cgcggacaac gcgcgggtgt acgaggccgc gcagcgcgcg atcgagctcc gggacaacgt
      421 cctcgcgacg gtgtcgcacg atctgaggaa cccgctcagc gcgatcatca cggcggccgc
      481 ggtgatgacg aagcgcgcgg cgtcgcgcgg gggggacaag ggggacacga aggcgatcca
      541 ggcgatccag cgctcggcgc accggatgga ccggctgatc cacgatctgc tcgacttcgc
      601 gagcctgcgc gcgggccggc tggcgctgca gcggcaggcc caggatccgc gggagatcgg
      661 ccgggaggcg gtggagacgt tcgagtcgct ggcgcaggag aagggggtcc gcctgagcgc
      721 gacgtcgggg gatgatctcc cgctggtcgt ctgcgatcgc gatcgggtgc tccaggtgct
      781 gtcgaacctg ctgagcaacg cgctcaaggt gacgggtccg caggggtcga tcacggtgcg
      841 atgtgagctc cgggaggagc atgtcgtctt cgcggtggcg gacacggggc cggggatccc
      901 ggaggacgag ctgccgtacc tgttcgagcg gttctggcgc ggccagcgga acggctacaa
      961 ggggaccggg ctcgggctgg cgatcgcgag ggagctcgtg gccgcgcacg ggggggcgat
     1021 cagcgtggag agcgaggtgg gggtggggac cacgttccgg ttcacgatcc cggtcgggag
     1081 cggcgagggc tgaaccggag ggctggaggg ccggcgcgca gcagggacgg ccgcaccggg
     1141 gctgcgtgcg ggtgtggagg accggcgtgg cgggcctgaa gcgggcgcgg cagtggcctc
     1201 ggacggggcg gggggaggag tggacgatcg atcgcgccgg ccccagaggt cctcggaagg
     1261 aggaagtatg ggaaacgagc ggagcaagga ccagctgggc gtggaacggc ccgagcgcga
     1321 ggtcagcgag gagaagcagc cgcacccgca ggcggaggtg cccggggtgc gcggggcgat
     1381 cacctcgtcc ggagagaggg ccgatgcgcc tgaggatgag gtcgagacct tcggcagcga
     1441 agggggcgcg ggtaactaca agggagggcc ggagtactcg aacaaggaga tccctccgga
     1501 gagctcgggg gggaagccgg cgtagcggaa gggctggcgt ggcagcgtag tggagagcga
     1561 gttcgccttg cgacgctgct gccggggttt gcgctgggcc cagcggtggg ggggcccact
     1621 cccggcgaga ggcgtggcta gccctggcac aacctgctcc tcgtctttcg tctttcgtct
     1681 ttcgtctttc gtctctcgtc tgtcgtctct cgttcctcag tctcccctct ctcgtgaacg
     1741 tgaacgtgaa cgtgatcggt atgcagcgac acgcttgctc acggcatacc gccatgacca
     1801 tggcagcgat tcgagttagc gagatcgctg cgaacttccc tcggcggcaa aagagatctc
     1861 aagactgaac gagattcgat caaagcgttc acgttcacgt tcacgaaaga gggcagagcg
     1921 aagaacgaaa gacgaaagac gaaagacggg ggcggtcgcg cgactcatcg tctgagcgaa
     1981 tcctcgcgac cagttccggt acaagcgcga tgccccccga gctcccctcc ccccttactg
     2041 ctgctgctgc gccggtctgg gcgcacaccg ctgcatgtac gccggctcgg ggcagccctc
     2101 gtgcgtcagc acctcgctct ccttgcactt cacgagcgcc gcccggatat caagacaccc
     2161 ccccggcccc gcctccacac accggtgctg cgtcgttgtc ccgatcgcac acccatccac
     2221 ctgcccctca ggacacgtga gcagcgcccc ggtagaacag tcatccccct cccgaccggc
     2281 cgccgccgtc cccgtggtcg ccgtcgtgcc ctgcgccgcc tgcggcggcg tgcaggcggc
     2341 gctcgaggcc agcgcgatcg cgagccccgt gaagaagaaa acgcccctcc ggggcgagct
     2401 gctccgtgca ttcatgccat cgttctccgt gggtcagggc cggacggaga cccgaaagac
     2461 aggtcgccgc ccggcgcgcc cggcagacta ctccacggag cggcatcctc ccggcgcttt
     2521 cgcgcctccc cagagaacgc ctggcgcacg cagcgccccg gtcagaacgc gccgccgccg
     2581 tgcgcgatca cagcccagct gtccccgccc gtctgctccg ctgcgccgcg gacgctcaga
     2641 tcatcgagaa acgcaggacg gaagttgaac cgagcgccca gcttgatgtt ccgcgtgacg
     2701 agccgctcca cccccgcggt gagcggcacc gacagcgcga acgcgtcgcc gccctcgccc
     2761 gcccagccca cgtaccccac gcccgcgacc acgaacggct gcacgatcgc ctcgtgggcg
     2821 cgcagcacat tgtaacgaac ccccgcgtcg aacgaggtca tcacgagcga ccgccccgcc
     2881 gtcgtgcgct cgttcaccga gccgatgtag ttgccctcga ccgccagccg cggcgacagg
     2941 gtccctgtca cacgcacgtt ccaggtgggg ccgaccgccg cggtgccccc caggtagccg
     3001 agcatgccga agccgccctc gaccgcgatc gtgggctcgg gaaggcgctc aatcagcggc
     3061 tgatccgccg gcgggacgtt gcccgccggc cgcccgccgc gatccgccgc cgtgtcctgc
     3121 gcatccgccg caaacgccag cgccatcatg gcagcgacgg ccatcgccgc cgccgcgagt
     3181 cgtcgcatct tcatcggtct tcctctcccg tcgacctgtt ccgccatcga cgatcggcct
     3241 cgcggcggtg cacaccgtgg gccacatgac cctgtgcagc gcgggtccgg cggcgccgcc
     3301 cgctccgcac gcccgccgcg ccgcggaacc gagcggcgat cgaaaccgca acgcgacgcg
     3361 cccgtaggag ggatcggcgc gcccgcagcc tctgcccgac cgccgcgagc gcgccgtttc
     3421 gaccggagag attgaacccg atggcgagga ggagcggcgt tcccggccct cttgccctct
     3481 tctcgcttcc cgccaccccc accgccctgc tcaattgtga cgagggcagc gcggcgacga
     3541 cgggcggcgg gcctcgacca cagcactcca ggaggcgaac gtgacgacga tccgaacaag
     3601 gaccctgctc ctcgcggcgc tcgcggccac aggcgtgagc gcggccgcgt gccaggaaga
     3661 gaaggcgccc ctcgcgcccg ccgcgaccga gctcaaggcg ccggcggcga aggtgcccgc
     3721 cgcggcgacc ttcgcgatcg acagggcaaa cagcaaggtc gagctcatca tggatgcgcc
     3781 gcaggagaag atccgcggac ggatcgaggg cgccgccgag gggacgctgc acgtcgaccc
     3841 cgccgacgtc acgaggacga cgggcctcat cacgatcgac atctcccccc tcgagctgct
     3901 ccagaccggc atgggcgacg acggcaagcc cggccaggag aagaagagcg atctccagaa
     3961 cgagcacgcg cgcacgtggc tcgagatctc gaaggacacc cccgccgacg tccgcgagaa
     4021 gaacaccagg gcccagttcg cgatcaagtc gatctcgacc tccggcgaga aggacctctc
     4081 gaagctgtcc ggcgccgagc ggagcgtgac cgtcaccgcg tccggcgacc tcctgctcca
     4141 tcagcggcag gccccgaaga ccgtggagct cgtggccacg ttcacgtacg agggcgacag
     4201 gctcgcccgc gtcgccgtga agacggcgaa gccgttcgcc gtcgggctcg ccgaacacga
     4261 tgtccgcccg cgcgaggcgt tcggcaagct cgcccagaag acgctggagg tgctctcgcc
     4321 caaggtcgcc aaagaggcga tggtgtcgct cgaattcacc gcgacgcccg tgaagaacga
     4381 cgccgcggcg cccgcgccgg acgccgcgcg gtgaggccgc ggaccgccgc gcggcgctgg
     4441 acgatgagcc gttgcggcgc cgcggcgggt ctgagatgaa ccagcgatct cggccgccgc
     4501 ggaggaaacc gcccccggct tcgaccgtat gggttgctgg ccatcgagac gtgaaccaga
     4561 ggagcacacg atgttgtcga agaagagcat ctacgagacc ctcgccgcgc tgagcgccgg
     4621 cgccatggtg gtgagcggct gcggcggcgc gcaggcgccg gtcaacgcgg ccgaggtccc
     4681 cgccgagcac gagacggccc cggccgcgcc caccgaggcg acctcgggcg acgacgccgc
     4741 gggcgccacc acgcccgcga ccccggcgga gccgtcctcc accacggagg cgcccacccc
     4801 cgcgcccccc accgacgtgc agtccgccgc gaccgcgccg caggtcgcgc ccaccgccac
     4861 cccggccccc gccgcgcccg ccccgccctc gcccacgacg ccggccaagc cgaccgccaa
     4921 gaagccggcc ggcaagaagc ccggccacgc gggctgtggc gctggcacct gcggctgatc
     4981 ccggcccgcc ctcccgccgc atggtcccca cgaccggcag cgcgccgacc ggcgtcggcc
     5041 tcgggctccg gtgggagttc ctcgaggagg tgctcgccgc gctcgacgag ggcgcggcgc
     5101 tgcccgtccc cttcttcgag ctctcccccg agaactacat gcgccgcggc ggctactatc
     5161 ccgccgcgat cgagcgcatc cgggagcgcc gcccgatcct gacgcacggg ctcaccctgt
     5221 cggtcggcgg catcgacccg ttcgacgcgg gctacctgcg cgcgctcggg gatctgctcg
     5281 ggcggctcga tccccccttc cacagcgacc acctctgctt ctgcggggtc gacggcaggc
     5341 tcctgcacga cctgctgccg ctcccgctga cgcccgcggc cgccgcccac gccgcggccc
     5401 gcatccgcga ggtggaggac cggctcgagc gcccgatggc ggtcgagaac atcacgagct
     5461 acctcgtccc gggccgcgcc tcgctcgacg aggccgactt cctcgtcgag gtgctcgagc
     5521 gcgccggctg cgggctgctg ctcgacgtga acaacctcta cgtgaacgcc aggaaccacg
     5581 gcttcgatcc ggtcgcgttc ctggagaaga tcccgccccg gcgcgtcgtg gcgatgcacg
     5641 tcgccgggca cgagtggcgc gacgaggcgg aggtcctcgt cgacacacac ggcgccccgg
     5701 tgatcgagcc ggtactcgat ctgctcgccc gcgccgtcgc gcggacgggg ccggtgccgg
     5761 tggtgctcga gcgcgaccac gacgtgccgc cgctcgcggc gctgctcgac gagctcgcgg
     5821 cggtggacgc ggcgtaccgc cgcgggctcg ccgcccggga ggcgcaggcg tgagccgcgc
     5881 gggaggcgcg ggcgggggcc gcccgggaga cgcgggaggc gcaagcggag gccgcccggg
     5941 aggcgcgggc gggcaacccg cgcccgcgcc gcccgagctc gcggcgctgc agcgggcgct
     6001 ccagcgcagc gtgagcgagc cggacggcgc ggcgatcgcc gccgatccac gcgcgtggct
     6061 cgcccgcgcc gggctcgacg ggcccgacct cgacgcgatg gcgtcgctgc ccccgaagcg
     6121 gctgctcctc taccggagcc tcgtccgcag cgggctgacg agcgcgatcc ggaacgagat
     6181 cccgcggacc gcggcgcggc tcggcgcgct gttcgaggcc tacgtctccc gcttcctcgc
     6241 ggaggagctg ccccgatcgc cctacctccg cgacgtcgcc ttcgagttcg tcgccttcgc
     6301 cgcgccgcgc tgggccgccg atccggaggt cccgtcgtac ctcgcggatc tcgcgcgcca
     6361 cgagctcgcc gcgttcgtgg cggcgtgcgc cgagccggag ggcgcggcgg ccggcgcgcc
     6421 gggctccggc gacgagctct cgctcgaccg gggcgcgcgc ttccagcggg ccgcgacgct
     6481 cgtgcgctac gaacacgcgg tgcaccggct gcagggcggc gaggcggcgc gcgacgtgcc
     6541 ggcgcgcgag cccgtgagcc tgctcgtgta ccgcgacgcc gagcacgagg tccgctacct
     6601 cgagctcacg ccgctcgcgg ccgagatcct cggccgcctc ctcgagggcg aaacgctcag
     6661 ggacgccgtg gtcgcgggct gcgcggccct cgggcgcccg gtcgacggcc cggtgctgga
     6721 gagcaccgcg gccttcctga gcgacctcgc ggagcgcggc gcgctgctcg gagcgtcgcc
     6781 gcagtcgacg acctgagcag tggcacgaga aatttgcgca cgcctcggtc cgcgtcgacg
     6841 gctatcttcc cggccggcgt tcctggccgg aggtgacgtg tgatcccgga taaagtcgag
     6901 cgcgcatgca gcgaaccctc ttctggttgg cggccggcct gtggctcggg tgcggcagct
     6961 cgggtgctgg aacgccgaag aacggggcct cgacgggggc ttcgggcggc ggtggccccg
     7021 tgagcccgaa cggcaacgca ggcggcggcg gcaacgcagg cggcggaggc ggcaggggca
     7081 gcgcaggcgg cggcgcttcg gcccccgggc gggggccgtt cgtctatgtc ggaggccacg
     7141 cggggatctt cgtcttccgg ttgagcgagg ccgacggcgc gctcgacgcc gtggagggcc
     7201 cgctcgatgc cgagatgaac ccgaccttcc tcgccgtcga tcccacacac cggcacctct
     7261 tcgcggtgaa cgagctgagc gaggtggacg gggaggcgtc gggcgcggtc agcgcgttcc
     7321 agatcggcca ggaggacggc aaactcgcgt tcctcaacag gatttcctcg aagggcaagg
     7381 gccctgccca cctcgccgcg gatcgctccg ggcgcttcat cctggtcacc aactacggcg
     7441 ggggcacggc ggcggtgctc cccatcggcc cgggaggcga gctcggccag gcggtcgccg
     7501 agaggacctt cggtttgcgg tcgaggtcgc atcacgccgt aaccgatccg gcgaaccggt
     7561 tcgccttcgt caccaacctc gggctcgacg cgatcgcgca gctcaccttc gacgaggcca
     7621 cgggccagct cggggcgagc gacccgccgg ccatcacgtt ccccaggggc acgacccctc
     7681 gccacctcga gttccacccg aacggccggt tcgcctacgt gatcaacgag tcagccggct
     7741 cgatcaccac cttgcgctac gacccggcgc gcgggacgtt ctccgccgtg gccaccgtct
     7801 cgacgttgcc gcagggcgtg agccgcgagg acaacacctg cgccgagatc caggtgtccc
     7861 cgtcgggcaa gttcgtctac ggctcgaacc gcggccacga cagcattgcc atcttcgccg
     7921 tcgacccaga gcgcggaacg ctcacgcccg tcggccacca gccgacgggc ggcgcgacgc
     7981 cgcgccactt ccagctctcg ccggcgggca agctgctgct cgtcgcgaac caggactcgg
     8041 acaacctcgt cgcgttccac gtgaacgagg cgaccggcgc gctcgatccg accggccgtg
     8101 tcaccgcggt ccccgagccg acctatgtcg ggatcgtgca cctgacggcc cggtgaacat
     8161 gcctgtgtga cggccgggct tcgcgcccgc cggccggccg cgccgccccg ggcgggctca
     8221 cctcctgcgt ggccccgggc ccgggagtgc gcccgccggg acggcggcga cgctggggcg
     8281 ccgcgaaatg gttccaaccg ggcccgctgc cactaagatg accctgacgc acgcgagcgc
     8341 ggcgcttcga tcggcgcccc gccgcggcgc gtagggatct catgagccag aacctggacc
     8401 gcagcgaccc gctcaccatc gcggggaccc tcatcgccga caagtacagg atcgagcgcg
     8461 ccgtcggcga gggcggcttc agcgtcgttt acaaggccga gcacatcatc tggaagcagc
     8521 cggtcgccct gaagtgcttc accctgctcg cgaacgcccc ggccgaccag cgcgagcagc
     8581 tgctccaggg gttcatccag gagggcaagc tcatggccga gctctcgagc cgctcggccg
     8641 cgatcgtcca ggcgcgcgac gtcggcacct tcaacgcgcc cgacgggcag tggctgccct
     8701 acatggtcct cgagtggctc gacggcatgc cgctcgatcg ggtcttcgag gaggaggcgc
     8761 ggcaggggct gccgcggcgc gacctctacg cgacgctcgc gctgctcgag tccgcggcgg
     8821 tcgcgctcga gctcgtgcac tcgcgcaaca tcgcgcaccg cgacatcaag ccggccaacc
     8881 tcttcgtcat cggccggccg cgcgacccct ccgccttcgt gaaggtgctc gacttcggca
     8941 tcgccaaggt gatggccgag cacgccgcgg cggcgaccgc gctcgcccag accggcaagg
     9001 agatcaccgc gttcacgccg agctacggcg cccccgagca gttcagccgc atccacggcg
     9061 cgaccgggcc gtggaccgac gtcttcgcga tggcgctcat catggtcgag gtgatgctgg
     9121 gcggagcgcc ggccctccag ggcgacgact acatgcagct cgcggtcgcg agccgcgatc
     9181 cggcgcgccg gccgaccccc cggaccctcg gcctcgaggt gagcaacgag gtcgaggcgg
     9241 tcttcgagaa ggcgctcgcc gtggcgccgt cggatcgctt ccccaccatg gggcgcttct
     9301 ggtcggcgct gcaccgggcg acctccctcg acgatccgag ctgggcgatg agcccgggcg
     9361 gcggctccct cgcgccgccg tccggcgccg cgccgccgcg cgcctcgtcc ccgcggatgt
     9421 cctcgtcccc gcggatgtcc tcgtccccgc acatgtcgtg gccgcaggtc gcgccgacga
     9481 tggcggcgcc cccgaccgcg ccggccccgg ggaccgtccc tccggcgacg tcccagaccg
     9541 ctgtcctcca ggagatgagc accaccggcg gcaccgcgaa cgacgcggcg acgcagcgct
     9601 ccgcgccggc cgcgccgcgg tcgaagggcg cgctggtgct cggcggcgcc gcggtcgtgc
     9661 tcgcggccgg cggcgcgatc gccgtccagc tgctccgcga gcccgccgag ccgccccagg
     9721 ccgacacgtc gcgcaccgcc ccgatcgcct cgtccgcccc accgatcgcc agcgcgagcg
     9781 cgccggccgt gccggccgcg cgcccgaccg agtgcccctc cgggatggtg ctcgtcccgg
     9841 gcggcaagtt cttcatgggc tccgacgatc cggcgttcaa gctgtggcag cccgcgcaca
     9901 aggtcacgat cgacacgttc tgcatcgacg tgcacgaggt gaccgcgggc gagtacaagg
     9961 cgtgctcgga caagggcgag tgcaagcggc ccccggccgc gcccgacttc cccaggccgg
    10021 acggggtgtc ggcagccgag cacgagcgga cgctcgcggc gctcgccgag ctctgtacct
    10081 tcggcgagcc cgagctcgcg cagcacccga tcaactgcgt gccgtggagc ctcgcggacg
    10141 cctactgcgg ggtgcagggc aaacgcctgc cgaccgaggc cgagtgggag tacgcggcgc
    10201 gcggctccga cgggcgcaag ttcccctggg gcgacgagcc gggcgaccac accttcatga
    10261 acgcgtgcgg cgccgagtgc acgaagtggg agacggcgcg gaagctcaag ccgagcccgc
    10321 gtatgtacga cgccgacgac ggcttcttcg gcacggcgcc ggtggggtcg ttcccgaagg
    10381 gcaagacgcg gttcggcgcg cacgacaccg tgggcaacgt ctgggagtgg accgcggact
    10441 ggttcgcgac ctacaaggac gaggagctgg tgaacccgaa gggcgcgccc gccggcgacc
    10501 gcaaggcgat ccggggaggc ggctacaacg gcggcttccc gctctggatg aacccggcgt
    10561 tccgctacca ccagctcgcg acggccagcg cgccgggcat cggcttccgc tgcgtgaccg
    10621 acctctagcc ccgtgcccgt ccccgcctcg cagctcggca acccctcgat caccggcccg
    10681 ctcggcacgc tcgcgttctc gcaggtgcgc ccgctcagcg cgtcgctcgc gctgcgcgcg
    10741 atccggtggc accagagcct cgagcggctc ggggtcatcc tgccgttcgc gctcgtgcac
    10801 gacgcggggc tgctcttctc gacgccgcgc gagcagctcg agctcggccc gcgctgcgac
    10861 ccgaaggagc tcg
//
