LOCUS       NZ_CP012673            22226 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Sorangium cellulosum strain So ce26 chromosome, complete genome.
ACCESSION   NZ_CP012673
VERSION     NZ_CP012673.1
KEYWORDS    RefSeq.
SOURCE      Sorangium cellulosum
  ORGANISM  Sorangium cellulosum
            Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae;
            Sorangium.
REFERENCE   1  (bases 1 to 14557589)
  AUTHORS   Zaburannyi,N., Bunk,B., Overmann,J. and Mueller,R.
  TITLE     Sorangium comparison
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 14557589)
  AUTHORS   Zaburannyi,N., Bunk,B., Overmann,J. and Mueller,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-SEP-2015) Department of Microbial Natural Products
            (MINS), Helmholtz Institute for Pharmaceutical Research Saarland
            (HIPS), Campus E 8.1, Saarbruecken, Saarland 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SMRT portal v. 2.2.0, HGAP v. 3.0
            Genome Coverage                   :: 134x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002950945.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 11:58:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,531
            CDSs (total)                      :: 10,457
            Genes (coding)                    :: 10,397
            CDSs (with protein)               :: 10,397
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 6 of 60
            Pseudo Genes (incomplete)         :: 58 of 60
            Pseudo Genes (internal stop)      :: 2 of 60
            Pseudo Genes (multiple problems)  :: 6 of 60
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:39:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9244948
            Orig. end                         :: 9267174
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012673.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from German Collection of Microorganisms and
            Cell Cultures GmbH, Inhoffenstrasse 7B, 38124 Braunschweig,
            Germany.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22226
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="27"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..22226
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22226
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12226](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12226
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            30..929
                     /locus_tag="SOCE26_RS33295"
                     /old_locus_tag="SOCE26_066920"
     CDS             30..929
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012234930.1"
                     /locus_tag="SOCE26_RS33295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_066920"
                     /product="hypothetical protein"
                     /protein_id="WP_104983625.1"
                     /transl_table=11
                     /translation="MRTHRPVLLATLLSAVAVAMSAVPGCGDDETRASSGGPDRTGSDF
                     LSSYAKALCERTFACCDAATRAAHDLDASSADTCASELEAILVAVSGGGEVKGTFVPEK
                     AEACLAEVDAAPCAELQILGVLLGVNDGFTPSCLDAFDGSVPEGETCGTDWDCVRDRCL
                     YTGDASGQRTSACTARAAAGERCSSAFDCDEALRCDQPSPSNAGTCAPRLAVGGSCEGS
                     LDCQEELRCGQEGTCQARQQAGGPCASDGDCAAGTTCDGATCAPLGAAGAPCSSDSDCA
                     SFACGDATGTCADVCKGS"
     misc_feature    54..56
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1091..1846
                     /locus_tag="SOCE26_RS33300"
                     /old_locus_tag="SOCE26_066930"
     CDS             1091..1846
                     /NRPS_PKS="Domain: PKS_KR (5-120). E-value: 2.9e-07. Score:
                     22.5. Matches aSDomain:
                     nrpspksdomains_SOCE26_RS33300_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020733942.1"
                     /locus_tag="SOCE26_RS33300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_066930"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_104983626.1"
                     /transl_table=11
                     /translation="MQDKPVALVTGANKGIGHAIAKELAARGHTVLVAARDLARGEAAA
                     KQITGDARAIALDVTNADSIAAAAARIRRELGRLDVLVNNAGIAKGAAQSGVTVDEIAR
                     SGRPSVASLADVRAVFETNVFGVIAVTQAMLSLLREAPAGRIVNVSSRLGSMTWISDPA
                     NPNRSVGGVAYSPSKSALNAVTIAFAQELAGTAIKVNAVCPGYVATDLNNHSGTRTVAE
                     GAREPVRLALLGPDGPTGTFSDDAGPIPW"
     aSDomain        1106..1450
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SOCE26_RS33300_PKS_KR.1"
                     /evalue="2.90E-07"
                     /label="SOCE26_RS33300_PKS_KR.1"
                     /locus_tag="SOCE26_RS33300"
                     /protein_end="120"
                     /protein_start="5"
                     /score="22.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGANKGIGHAIAKELAARGHTVLVAARDLARGEAAAKQITG
                     DARAIALDVTNADSIAAAAARIRRELGRLDVLVNNAGIAKGAAQSGVTVDEIARSGRPS
                     VASLADVRAVF"
     CDS_motif       1112..1189
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SOCE26_RS33300_0001"
                     /evalue="6.60E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="SOCE26_RS33300"
                     /protein_end="33"
                     /protein_start="7"
                     /score="18.8"
                     /tool="antismash"
                     /translation="LVTGANKGIGHAIAKELAARGHTVLV"
     gene            1993..3744
                     /locus_tag="SOCE26_RS33305"
                     /old_locus_tag="SOCE26_066940"
     CDS             1993..3744
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008134 - transcription factor binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020465107.1"
                     /locus_tag="SOCE26_RS33305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_066940"
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="WP_234022666.1"
                     /transl_table=11
                     /translation="MSRDESLVSLLPRLVSATYFDEAATAVLQTMFACAEEALADSPFA
                     SRARLLRGVVHLRPEGSYQRLFGVDRLSGARIEGTGYLTSGSVWSWIEKHRCSVSIDVQ
                     RASLRSWMPDGEIELRDPSETAGMPGDATRERMLGRDTTHVHVVPLRAPGGSVDGMITL
                     EASCRGAAGRELPWDVCHEELEILASIAGAFIAARALPLRPDDPVGPDEFLPVVGQSTA
                     HLVELLRAFAPRDDTILITGPTGAGKSRLARWCHEHSQRRGQPFESLDLLGVPEDLQMA
                     ELFGWKRGAFTGAVKDNPGAVARAAKGTLFLDEIDKLSLKAQAGLLRFIEERSYRMLGD
                     DGAGERRADARLLVGTNADLRAAVRAGRFREDLYYRINVLPVRLLPLAERLDELPRWAD
                     YMLNRRHREADGKGTARFEPEAMKLLVSAPWPGNLRQLDNIVRRVYALQLAGQSGLGGD
                     LVIQRRHVERALTFDGDAEPSALVKLLWRAALSFVNEAERRRGGNAPLSLELSDVFRGM
                     VLGAAVHRTGNRDEAFTLLGQEPMLKNRNHHRALRRELSRVREVLDLLGGEVDPDLLAV
                     LEADKDS"
     misc_feature    complement(3788..3803)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            3806..7870
                     /locus_tag="SOCE26_RS33310"
                     /old_locus_tag="SOCE26_066950"
     CDS             3806..7870
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012232859.1"
                     /locus_tag="SOCE26_RS33310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_066950"
                     /product="TOMM system kinase/cyclase fusion protein"
                     /protein_id="WP_104983627.1"
                     /sec_met_domain="Pkinase (E-value: 3.9e-43, bitscore:
                     146.9, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRYVENGAALIPGATFEGRYEILARLGEGGFGVVHKARQLTTGQ
                     PVALKILRLAEQGGAAQADRRVARFLRETRLCAQLHHPNIVQLVDSGQMEDGSLYTVFA
                     FAPGDNLAALLEREGALAPPEARHLMLQVLDALACAHAAGVVHRDLKPSNIMVIPTGAR
                     RNALVLDFGIGATLDEERSARLTGSHDALGTPGYGAPEQWRGAEPSPRADLFSWGLVFL
                     ECLTGKPVYGGTEAEIFYRLLGPDPVPIPAAIERHPLGALLARALRKNEGARDATAGEL
                     FEALEACNLRGLSREALFGADGTPSGGDTRSSVSIATVAASRDRRRGPAPPAPDGERRE
                     LTALCCHLSARAAAAQTLDVEAADDLLRSALALCADVGRRHGGYVAAAFGADLLLYFGY
                     PSAAEDDAKRAARAALAMAGAVQAGDQRSAAQGVGIEVSVGLHTGPVVDGSLGDLDGAC
                     LVTGSTPRLAAQLAALAAPGSVTVSAASQGLLRVSFDLESEGARSIEGMAAPVQTFRLR
                     KEHGDAARWPTPEGSKTPLYGRDQELGLLVERWRRACEGAGQSSLVTGEPGIGKSCLAR
                     ELRHRLAHEAHTFLEARCSPDTQNSPLRPVIDLLERAFGLDQALDAGSKTARLEGELAR
                     HGLTPAEAMPLFLPLFSLPFGGPYAPLDVSAQRQKALTLQAIASLLLAMADEQPVLLLV
                     EDLHWADPTTMEFLAQLVREAPAVPMCIIMTARPEFSPSFSTADVLLLPLSRLERPQME
                     EMLTGLLGNKALPPAVIEQVADRADGVPLFAEELLRMMVDSRLLVEQEDRYDLTRPLSG
                     AAIPGTLRALLTARLDRLLRAKQTAQLAAALGREFSLKVLSAASPLGPEAVAEDLERLM
                     SAGLVLRKRRQKDAVGVFKHALVRDAAYESLSTGARRRSHARIAATLEERFPEVVRMRP
                     DLLAHHHAAAEQMQEAIGYARKAAHQALGRSAYAEASAHASNVVGWLGALPAAERVEAE
                     LGANSIRLQALMSTQGWASPDVRALAEQSRALLPGSKTTEHTASTLFGLYMHYHVASER
                     AACRQVADELVAFADRIEDPSLQCVAATAQGVGFHAEGRFLDAETWFDRALALYDPARD
                     WQQGSAFGMDCRVWAAGQLAWVQWGMGRTTRAFQLANEAIAWAREIKHVPSLGIALLYL
                     GQIQHMNGDKPAVHRTTGELLAASKAYGLPAFEGYGAALASWAAGDLQGVEAILGTLKS
                     LHCNLALTYYGSFLADIEADAGRLHQAIAHVETCLSMCAELGERFFEVELLRRRARYEI
                     RLPEPDRDAVRELLARARQLAGERGMHRFEAAAIQEHRRIFGDDAALVRRLTQLHESFP
                     DLKLLSPRSEP"
     gene            7867..8652
                     /locus_tag="SOCE26_RS33315"
                     /old_locus_tag="SOCE26_066960"
     CDS             7867..8652
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03795"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03795.1"
                     /locus_tag="SOCE26_RS33315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_066960"
                     /product="BMA_0021/BMA_0022 family TOMM bacteriocin"
                     /protein_id="WP_104983628.1"
                     /sec_met_domain="TIGR03795 (E-value: 3.6e-14, bitscore:
                     52.1, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIEPSKAWENGGTGSAAPFPRLRTAYLRAIARAWRDPSFLEQLV
                     RKSKDDPYGVLPFLEKEYRFRFPFNVKFAISDDPRPQWRPNEMLGWLADGDEIDITLPG
                     PPALRKVRVHDDSLTTLADAIALYCQWFPSMLGPPRDGVSQPPDDFAEFGVLTARLLAM
                     MWGDEKFKEQLLGERDARRLVQAAMGVIVHWNFNLKFSYLDWDEFWNDIDYQGQPEGTI
                     PARVKITVNIPQNPPDDAVWPVALAAYNDTGPQYPFTCA"
     gene            8779..9966
                     /locus_tag="SOCE26_RS33320"
                     /old_locus_tag="SOCE26_066970"
     CDS             8779..9966
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012232861.1"
                     /locus_tag="SOCE26_RS33320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_066970"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_104983629.1"
                     /transl_table=11
                     /translation="MRNGIAIIDIDRHVMEPMGLWPEYLPAKYRDVAPDVRPLAPPDEP
                     LGARLARLGDHALLPTPPVVTVGGKPICRGMTEVGYIEVGLHAEEHRRELIAAETAAGQ
                     LATMDAAGVDVAVLHPTYTGFLVYDEEIDADRSRAYARAYNRWLADQCRRDPTRLKGAA
                     LISRHDPAQMVADLDAGLADGLSAAVVRPNPVRGRTLGAPELGPFFAACEANDIPLLLH
                     EGTHTRVQTAGASRFQTHFAQHACSHPLEAMMAFLALLEGGVFERHPGLRVGFLESGCG
                     WLPYWLWRLDEIEYAQLSNEVSGRVNRRPSSYFRRQCWIAFEPGEAMLAHSVGAIGEDR
                     VVFGTDFPHVDHDPTIVARLFDGGAPLPGEVLRAALWDNPARLMGLSEAARPRGA"
     gene            10001..12226
                     /locus_tag="SOCE26_RS33325"
                     /old_locus_tag="SOCE26_066980"
     CDS             10001..12226
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012232862.1"
                     /locus_tag="SOCE26_RS33325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_066980"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_104983630.1"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 8.9e-23, bitscore:
                     79.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 2.6e-16,
                     bitscore: 58.7, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 2.2e-07,
                     bitscore: 30.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03882 (E-value: 7.4e-50, bitscore:
                     168.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 1.4e-93, bitscore: 313.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 5e-79, bitscore:
                     265.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDALELSQVLAWKPTLRVERADDGVVFLIGERERFVLSGARMAEV
                     AMLVDGQRTVDDIVCAVRPRISEPEALYTLSGLAARGYLVPAAPELPSERAAFWRGVGL
                     DGEAAAEALSRTPVSVLALGEAAAAGWMTEALEQAGVRIDGEAAVRVVVSDDPLRPELA
                     SINRRALREGTPWFLIKPAGVQPLIGPLFEPGAGPCWDCLAFWMRQNRPVEELLRRRRG
                     HERHVAPPRAATEASVRTACGLGALAIARALARGDTSAAHALSSRVLALDLATLQTTTH
                     AVVRRPQCPTCGDPGRMAAVGERPIELQPVEKAHYEDGGYRRQAPRRTYERYQHLVSPI
                     TGAVTHLVPMPGRDTELRAVYASGYLVCPRDGVPQTNVFDKGCAGKGRGADQARVSALC
                     EALERYSGVYQGDEARVRASKNELGASALAAGDLLNFSEAQYRARDRLNAQAADRRQRV
                     PEPFDPSVPMDWTPAWSLSRRERRYVPLAYCYAEAPAESGAAFCGPSSNGVAAGTCLEE
                     ALLQGLLELVERDAAAIWWYNRLARPAIDLDGFADPYFEALQADYARLGWAVWVLDLTH
                     DLGIPTCVALAHEARADRFALGFGCHLDPRLAVQRSLTELNQLFDPAGARRAPWDLERL
                     PDRVYLFPDPELPRVAAERLPRLGGADLRADIQECMRRLDGAGLELVAVDKTRPDIGLP
                     VVQVIVPGLRHFWPRFGPGRLYQVPCAQGWLARPLDEGELNPVPLFV"
     aSDomain        10016..10297
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SOCE26_RS33325_NHLP_CD_RRE.1"
                     /evalue="2.40E-25"
                     /identifier="RREFam015.1"
                     /label="SOCE26_RS33325"
                     /locus_tag="SOCE26_RS33325"
                     /protein_end="99"
                     /protein_start="5"
                     /score="79.4"
                     /tool="antismash"
                     /translation="LSQVLAWKPTLRVERADDGVVFLIGERERFVLSGARMAEVAMLVD
                     GQRTVDDIVCAVRPRISEPEALYTLSGLAARGYLVPAAPELPSERAAFW"
     aSDomain        10019..10255
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SOCE26_RS33325_Cyanobactin_D_RRE.1"
                     /evalue="7.00E-19"
                     /identifier="RREFam007.1"
                     /label="SOCE26_RS33325"
                     /locus_tag="SOCE26_RS33325"
                     /protein_end="85"
                     /protein_start="6"
                     /score="58.7"
                     /tool="antismash"
                     /translation="SQVLAWKPTLRVERADDGVVFLIGERERFVLSGARMAEVAMLVDG
                     QRTVDDIVCAVRPRISEPEALYTLSGLAARGYLV"
     aSDomain        10022..10306
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SOCE26_RS33325_Goadsporin_CD_RRE.1"
                     /evalue="6.00E-10"
                     /identifier="RREFam013.1"
                     /label="SOCE26_RS33325"
                     /locus_tag="SOCE26_RS33325"
                     /protein_end="102"
                     /protein_start="7"
                     /score="30.1"
                     /tool="antismash"
                     /translation="QVLAWKPTLRVERADDGVVFLIGERERFVLSGARMAEVAMLVDGQ
                     RTVDDIVCAVRPRISEPEALYTLSGLAARGYLVPAAPELPSERAAFWRGV"
     gene            12554..14074
                     /locus_tag="SOCE26_RS33330"
                     /old_locus_tag="SOCE26_066990"
     CDS             12554..14074
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016497.4"
                     /locus_tag="SOCE26_RS33330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_066990"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_104983631.1"
                     /transl_table=11
                     /translation="MKGRTRAQSTARRRPIAVAACVGLLLTLLAAGGEAVAAPVTVTNG
                     VQFTDTAGNVVRGHDGGMIKVGQYYYWFGANPHSDNRFQHISVYRSTDLHTWEFRRHVL
                     TEASAPGVKNLQRPKVIYNARTRQFVMFMRKENHPHPLEENRVGIATSPTVDGDYTYRR
                     DFRPLKEPSFDVSVFQDDDRDRTAYLISTTGNDQQHLTIYRLTPDYLYVAARELVLSNV
                     TREAQTMFKRHGVYFLLTSGVTGWQPNQTKYATATSIKGPWSAMANLGDRITYGSQPTF
                     VLPIQGSNTTSYLYMGDRHGNAWDGNINDSEHVWLPLQFPTNRTLSMRWHPRVSIDTTT
                     GEVSGVGSGPAYEELRPQHKTDECLAVRRFTNGSVVDDSQANGNGVGVILRPCGSAATQ
                     NQHWQVLHLGAGYHRIVARHSHKCLTVPSSSTADDTRVTQSTCGTGENQQWKITDLPGG
                     DFRITARHSGKCLTIRYDPDIKGGKAIQFTCEGTANQRWKRAGAPYSP"
     misc_feature    12626..12628
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14117..14130)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.54"
                     /tool="antismash"
     gene            14547..15995
                     /locus_tag="SOCE26_RS33340"
                     /old_locus_tag="SOCE26_067000"
     CDS             14547..15995
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012632.4"
                     /locus_tag="SOCE26_RS33340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_067000"
                     /product="RCC1 domain-containing protein"
                     /protein_id="WP_159397546.1"
                     /transl_table=11
                     /translation="MHEVKGNTQTRPNFCSFLVVAATLAAAAGCSAQDRRFSDSGTGGG
                     SIDAQGGGGAGASGGGGAGASGGGASGGGGGGDPGCQIPPDSPTLADAIMVAAGDSHTC
                     AIRHDGSLYCWGDNSFGQLGVPQAMAVSSSTPVRVLFPASLGTATITQIALTERATFAI
                     DSQLRLWAWGSNETGILANGSKDSMAHDAPAIVNDGTAPLLVRKIAPAWYSACALTSTS
                     SIYCWGANLFSSLGPDASGEESLVPVRAFNFTATAGPRAILARGIGSIGSCFSTGTAED
                     GLRCWGAIGGGYILTNTSASSQGGVNYSAHMPLIEAGATLPFSEISYGTNFGCARDDVG
                     GLFCWGTNNSSGQHGAEAPPAGTAAAIPGVWGPMSTGYVFVCAIDDQRRLRCRGSNEQG
                     QLGRSTPMMGDNARMEPVVLGDGTALAKVVAVSAGFFHTCAIVEGACGPTGPGQVLCWG
                     RGTLGQLGDGAGTSSAVPVEVKAP"
     gene            16316..16600
                     /locus_tag="SOCE26_RS54685"
                     /old_locus_tag="SOCE26_067010"
     CDS             16316..16600
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SOCE26_RS54685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SOCE26_067010"
                     /product="hypothetical protein"
                     /protein_id="WP_159397547.1"
                     /transl_table=11
                     /translation="MIEDAAHGLRVRVRGKRAHLPFAPRPSQSIESEGAFHEHGPLDIA
                     RRCDLGGFGTGCVSSWWNPRRTSDPVTKINIDGGKRWSVRDSYLTPLAS"
     gene            16827..17420
                     /locus_tag="SOCE26_RS54690"
                     /old_locus_tag="SOCE26_067030"
     CDS             16827..17420
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SOCE26_RS54690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SOCE26_067030"
                     /product="hypothetical protein"
                     /protein_id="WP_159397548.1"
                     /transl_table=11
                     /translation="MRTTRSIRGSDHAPVQRITHVAYGDDTQDQSLPDGCWDLVFMKRR
                     GRLQVLHTGLITHPVTLGCETGDEYLSIAFRPGVFMPGVPAMGMLDQGVLRPLANPRSF
                     LLGPRAFEVPDFENADDLVARLIGAGLLVAAPVVLHRALDRAGARRAFPGDGDAHGAGR
                     RSAGVLRFAVLGPACPRDLRAHRDAGAPAELDTV"
     misc_feature    17241..17243
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17383..18063
                     /locus_tag="SOCE26_RS33350"
                     /old_locus_tag="SOCE26_067040"
     CDS             17383..18063
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020742333.1"
                     /locus_tag="SOCE26_RS33350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_067040"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_234022667.1"
                     /transl_table=11
                     /translation="MTPARPPNLTQCKLCPMLDTMSSKDGETRTAILEAARRLVTEPGR
                     RGVSMAEIASAAGVSRQAVYLHFETRTQLLAALVRHVDEVHGFADLVRKCERAPDARAI
                     LSEFIGAWAGYVAHITDVARAMQAARATDEDAELAWRDRMRGFTGVCARFVARLQAEGA
                     LADEWSASDAADFLATILSIGNWQELIEERSWSRPRYVRAMRRSVEQSLLRPMEIETAP
                     RRRS"
     gene            18060..18530
                     /locus_tag="SOCE26_RS33355"
                     /old_locus_tag="SOCE26_067050"
     CDS             18060..18530
                     /NRPS_PKS="Domain: Polyketide_cyc2 (11-152). E-value:
                     2.1e-18. Score: 59.0. Matches aSDomain:
                     nrpspksdomains_SOCE26_RS33355_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022072.4"
                     /locus_tag="SOCE26_RS33355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_067050"
                     /product="SRPBCC family protein"
                     /protein_id="WP_159397549.1"
                     /transl_table=11
                     /translation="MSGAQPELLAQGSVDIGRPLHETFAYVSNMENFPTWFPGVAAMRE
                     LDTLEHGQVGKRYRETVRMPFGRTGTIDIEVKEARVGERLLTEGEGFLLPRMSVGFAAL
                     SDGETRVEWRMVSRNQRWWFRWLVVPLLRRVMRGRARDGLRKLRENLEREPS"
     aSDomain        18093..18515
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SOCE26_RS33355_Polyketide_cyc2.1
                     "
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.10E-18"
                     /label="SOCE26_RS33355_Polyketide_cyc2.1"
                     /locus_tag="SOCE26_RS33355"
                     /protein_end="152"
                     /protein_start="11"
                     /score="59.0"
                     /tool="antismash"
                     /translation="GSVDIGRPLHETFAYVSNMENFPTWFPGVAAMRELDTLEHGQVGK
                     RYRETVRMPFGRTGTIDIEVKEARVGERLLTEGEGFLLPRMSVGFAALSDGETRVEWRM
                     VSRNQRWWFRWLVVPLLRRVMRGRARDGLRKLRENLE"
     gene            complement(18799..19449)
                     /locus_tag="SOCE26_RS33360"
                     /old_locus_tag="SOCE26_067060"
     CDS             complement(18799..19449)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SOCE26_RS33360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SOCE26_067060"
                     /product="hypothetical protein"
                     /protein_id="WP_104983635.1"
                     /transl_table=11
                     /translation="MNWDGAHAALKETKVPSGYELVQLRRADVLALVEDLRGWYPDIVV
                     GAESCHLTPEFYYEQTMLADVAEDRPILPIVARHQGAIVAMSTFEKNASARTITCRMGA
                     IAPAHRGPSLALLGPMLLERLGRAIGAELAYYFATLKSPHQQVLAERQRYRLVGIMPAH
                     DRDMVRPGEVKRVYEAIYAKVLVPDDAIEVPPASALTVRTRAVWASLFGSLPA"
     gene            complement(20024..20275)
                     /locus_tag="SOCE26_RS54695"
     CDS             complement(20024..20275)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SOCE26_RS54695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159397550.1"
                     /transl_table=11
                     /translation="MAELDQVDGDGPELARRFYVGKKISCRGASRRALPGACRHGRAAA
                     EGRRRARLELLVVYAPNPATWTADAREGLYRIQPSPHD"
     gene            complement(20855..21280)
                     /locus_tag="SOCE26_RS33370"
                     /old_locus_tag="SOCE26_067080"
     CDS             complement(20855..21280)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SOCE26_RS33370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SOCE26_067080"
                     /product="hypothetical protein"
                     /protein_id="WP_159397551.1"
                     /transl_table=11
                     /translation="MLRTFDVQLSSDTTEETVIPRIVAAGREEIAAACASTSGAAIRVF
                     NPLALGDYSDVPCSAILNDIGEACSAPTSDPNDNGTGEAQQRLSPFSLGCADFVGGSAL
                     VSQFLLCPRATTERDRRRCDYWTGGGFFGLGLMCAAF"
     gene            21748..22122
                     /locus_tag="SOCE26_RS33375"
                     /old_locus_tag="SOCE26_067090"
     CDS             21748..22122
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SOCE26_RS33375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SOCE26_067090"
                     /product="hypothetical protein"
                     /protein_id="WP_159397552.1"
                     /transl_table=11
                     /translation="MSGAGDWTPVLSAGELGAVAVHLVELCHVAALDTGELAIVDGTRA
                     EDEAAASRSTATWSAPSGGPEGVVDERMGCLMKRACSPGCGAVAVDFSSDPLDWVWVGV
                     ALLVLVGMVAALVLRFRRRR"
ORIGIN
        1 caactacgat cggaccgagg aggttcttca tgcgcacgca tcgacctgtc ttgttagcga
       61 cgcttctatc ggccgtcgcc gtcgcgatgt ccgccgtgcc cggatgcggg gacgacgaga
      121 cgcgggcgag cagcggaggc ccggatcgga caggcagcga tttcctctcg agctatgcga
      181 aggccctctg cgagcgcacg ttcgcgtgct gcgacgcggc gacccgggcc gcgcatgacc
      241 tggacgcgag ctccgccgac acgtgcgcct cggagctcga agcgatcctc gttgccgtca
      301 gcggcggagg cgaggtgaag ggcaccttcg tcccggaaaa ggcggaggcg tgcctcgccg
      361 aggtggacgc ggccccctgt gccgaacttc agatcctggg cgtgcttctc ggggtgaacg
      421 acgggttcac gccgtcctgc ctcgatgcgt ttgacggctc cgtgcccgag ggcgagacgt
      481 gcggcacgga ctgggactgc gtccgggacc gctgcctgta caccggcgac gcgagcgggc
      541 agaggacgtc ggcgtgcaca gcgagggcgg cggccggaga gcgatgttcg tcggcgttcg
      601 actgcgacga ggcgctccgg tgtgaccagc cctcgccgtc caacgcgggg acgtgcgcgc
      661 cacggctcgc cgtgggcggg tcgtgcgagg gaagcctcga ctgccaagag gagcttcgct
      721 gcggccagga aggtacgtgc caggcgcgcc agcaggctgg cggcccctgc gcgtcggacg
      781 gagactgcgc ggccggtacg acgtgtgatg gcgccacgtg cgcgccgctc ggcgccgccg
      841 gcgcgccctg ctcctccgat tcggactgcg cgtccttcgc gtgtggtgat gcgacgggca
      901 cctgcgccga cgtctgcaag ggcagctgac cgcaggccaa agctggtcct cccccgcttc
      961 cgcgcacagt ctcaccatgg gcccaagctt atacagcccc gctctagtct cggcttgggc
     1021 attcttggcc gcctctcgac cggccaagaa tgcccaaggc agcgcccgcg gaggtcacta
     1081 tcccggggac atgcaagaca aacccgtcgc cctggtcacc ggggccaaca aaggtatcgg
     1141 ccacgcgatc gcgaaggagc tcgcggcgcg cggccacacc gtgctcgtcg ccgcgcgcga
     1201 cctcgcgcgc ggcgaggccg cggcgaagca gatcaccggc gatgctcgcg cgatcgcgct
     1261 cgacgtcacg aacgccgact cgatcgccgc cgccgcagcg cggatccgtc gcgagctcgg
     1321 ccggctcgac gtcctcgtca acaacgctgg catcgccaag ggcgcagcgc agagcggggt
     1381 cacggtcgac gagatcgccc ggagcgggag gccgagcgtg gcctcgctcg ccgacgtccg
     1441 cgccgtgttc gagaccaacg tgttcggagt gatcgccgtg acccaggcga tgctgtcgct
     1501 cctccgcgag gcgccggccg ggcggatcgt caacgtgtcg agccgcctcg gctcgatgac
     1561 ctggatcagc gatcccgcca atccgaaccg cagcgtcggc ggcgtcgcgt acagcccgtc
     1621 gaagagcgcg ctcaacgccg tgacgatcgc gttcgcgcag gagctcgccg gcaccgcgat
     1681 caaggtcaac gcggtgtgcc ccggctacgt cgcgaccgat ctcaacaacc acagcgggac
     1741 gcgcaccgtc gccgaaggcg cgcgcgagcc ggtgcggctc gcgctgctcg gtcccgacgg
     1801 accgactggc accttctcgg acgacgcggg cccgatcccc tggtgaggag acgagcgcgc
     1861 gccagcaagg agcgacaggg cgcgcacgga gagggctcgc gtccctcccg gacgcgctgc
     1921 gtccgccgcg gacgcagcgg ccaccgttcg ctctggaccc gcccccgttc tcctgctctt
     1981 ctgagcctcg ccgtgtcccg tgacgagagc ctcgtttcac tccttccccg cctcgtgtcg
     2041 gccacgtact tcgacgaagc cgccacggcg gtcctccaga ccatgttcgc ctgcgccgaa
     2101 gaggcgctcg ccgacagccc gttcgcaagc cgcgctcggc tcctgcgcgg cgtcgtccac
     2161 ctccgtcccg agggcagcta ccagcgcctc ttcggcgtcg atcgcctgag cggcgcgcgt
     2221 atcgagggca ccggttacct cacctccggc agcgtctgga gctggatcga gaagcaccgc
     2281 tgctcggtct cgatcgacgt ccagcgcgcc tcgctccgct cctggatgcc ggacggggag
     2341 atcgagctcc gtgacccgtc ggaaacggcc ggcatgcccg gcgacgcgac gcgcgagcgg
     2401 atgctcggcc gcgacacgac ccacgtccat gtcgtcccgc tgcgcgcgcc cggcggcagc
     2461 gtcgacggca tgatcaccct cgaggcgagc tgcagggggg cggccggacg ggagctcccc
     2521 tgggacgtgt gccacgagga gctggagatc ctcgccagca tcgccggggc cttcatcgcc
     2581 gcccgcgcgc tgccgcttcg cccggacgat ccggtgggcc cggacgagtt cctgccggtc
     2641 gtcggtcaga gcaccgcgca cctcgtcgag ctgctccgcg ccttcgcccc gcgggacgac
     2701 accatcctga tcaccggccc gaccggcgcc gggaaatcca ggctcgcgcg ctggtgccac
     2761 gagcactcgc agcgccgggg ccagcccttc gagtcgctgg acctcctcgg cgtgcccgag
     2821 gacctgcaga tggccgagct gttcggctgg aagcggggcg ccttcaccgg agcggtcaag
     2881 gacaacccgg gcgcggtcgc ccgcgccgcg aagggcacgc tcttcctcga cgagatcgac
     2941 aagctctcgc tcaaggccca ggcgggcctg ctccgcttca tcgaggagcg ctcttaccgg
     3001 atgctgggcg acgacggcgc gggagagcgc cgcgccgacg cgcgcctcct cgtcggcacc
     3061 aacgccgatc tgcgcgccgc cgtgcgcgcc ggccgcttcc gcgaggacct gtactaccgc
     3121 atcaacgtcc tgccggtgcg gctgctcccg ctcgccgagc ggctcgacga gctgccgcgc
     3181 tgggccgact acatgctgaa ccggcgccac cgggaggccg acggcaaggg cacggcgcgc
     3241 ttcgagcccg aggccatgaa gctcctcgtg tccgcgccct ggccgggcaa cctgcggcag
     3301 ctcgacaaca tcgtccggcg cgtttacgcg ctccagctcg cggggcagag cggcctgggc
     3361 ggcgatctcg tgatccagcg gcgccacgtc gagcgcgcgc tcaccttcga cggcgacgcc
     3421 gagccgagcg cgctggtgaa gctgctctgg cgggcggcgc tcagcttcgt gaacgaggcc
     3481 gagcggcgcc ggggcggcaa cgccccgctc tcgctcgagc tgagcgacgt gttccggggc
     3541 atggtcctgg gcgccgcggt gcaccggacg ggcaaccgtg acgaggcctt cacgctgctc
     3601 ggccaggagc cgatgctcaa gaaccgcaac caccatcggg cgctgcggcg cgagctctcg
     3661 cgggtgcgcg aggtcctgga tctgctcgga ggtgaggtcg atccggatct cctggcggtg
     3721 ctcgaggccg acaaggactc ctgacggaga ggtgccggcg ctctccgggc gcctccgagc
     3781 gcctccagcg accacagggt caagcatgca gcgctacgtc gaaaacgggg cagcactcat
     3841 cccgggggca acgttcgagg gccgttacga gatcctggcc aggctcggcg agggcggctt
     3901 cggcgtggtg cacaaggccc gccagctcac caccgggcag ccggttgcct tgaagatcct
     3961 gcgcctcgcc gagcagggag gcgccgcgca ggccgacagg cgcgtcgcgc gcttcctgcg
     4021 cgagacgcgg ctctgcgccc agcttcacca ccccaacatc gtccagctcg tcgactcggg
     4081 gcagatggag gatgggagcc tctacaccgt gttcgccttc gcgcccggcg acaacctcgc
     4141 cgcgctgctc gagagagagg gcgcgctcgc gccgcccgag gcgcggcacc tgatgctcca
     4201 ggtgctcgac gcgctcgcct gcgcccacgc agcgggcgtg gtccaccgcg acctcaagcc
     4261 cagcaacatc atggtcatcc ccacgggcgc ccgccgcaac gcgctggtgc tcgacttcgg
     4321 gatcggcgcc acgctcgacg aggagcgatc cgcgcgcctg accggcagcc acgacgcgct
     4381 gggcacgccc ggctacggcg cgccggagca gtggcgcggc gccgagccct cgccgcgggc
     4441 ggatctgttc tcgtgggggc tcgtgttcct cgagtgcctg acgggcaagc cggtctacgg
     4501 cggcacggag gccgagatct tctatcggct gctcggcccc gatcccgtcc cgatccccgc
     4561 cgcgatcgag cgccaccccc tgggcgcgct gctcgcccgc gccctccgca agaacgaagg
     4621 cgcgcgcgac gccaccgccg gggagctctt cgaggcgctc gaggcctgca acctgcgcgg
     4681 gctgtcgcgc gaggcgttgt tcggcgccga cggcaccccg tccggcgggg acacgcggtc
     4741 gtcggtctcg atcgcgacgg tcgccgcgtc gcgcgaccga cggagggggc ccgctccgcc
     4801 cgcgcccgac ggcgagcgcc gggagctgac ggcgctctgc tgtcacctga gcgcgcgagc
     4861 ggccgccgcg cagaccctcg acgtcgaggc ggcggacgat ctgttgcgct cggcgctcgc
     4921 cctctgcgcg gacgtcgggc gacgccacgg ggggtacgtg gccgcggcgt tcggcgccga
     4981 cctgctgctc tacttcggct accccagcgc ggcggaggac gacgcgaagc gcgctgcccg
     5041 cgcggcgctg gccatggccg gcgccgttca ggccggggac cagcggagcg ccgcgcaagg
     5101 cgtcgggatc gaggtgagcg tcggcctgca cacgggcccg gtcgtcgacg gcagcctggg
     5161 ggacctcgac ggcgcgtgcc tcgtcaccgg cagcaccccg cggctcgccg cgcagctcgc
     5221 cgcgctggcg gcgccgggat ccgtgacggt cagcgccgcg tcgcaagggc tgctgcgcgt
     5281 ctccttcgac ctcgagagcg aaggggcccg ctccatcgag gggatggcgg cgccggtgca
     5341 gaccttccgc ctccggaagg agcacggcga cgcggcgagg tggccgaccc ccgagggctc
     5401 gaagacgccg ctctacggcc gagatcagga gctcgggctc ctcgtggagc ggtggcgccg
     5461 cgcgtgcgag ggggcgggtc agtcgagcct cgtcacaggc gagcccggca tcggcaagag
     5521 ctgcctggcg cgcgagctgc gccatcggct ggcgcacgag gcccacacgt tcctcgaggc
     5581 gcggtgctcg cccgacacgc aaaacagccc ccttcgtccg gtgatcgatc tcctcgagcg
     5641 cgccttcggg ctcgatcagg ctctcgacgc gggcagcaag accgcgcggc tcgaggggga
     5701 gctcgcccgc cacggcctca cgccggccga ggccatgccg ctcttcctgc cgctcttctc
     5761 cctgcccttc ggcggaccgt acgccccgct cgacgtctcg gcgcagcggc agaaggcgct
     5821 gacgctccag gccatcgcgt cgctgctcct cgcgatggct gacgagcagc ccgtcctcct
     5881 gctggtcgaa gatttgcact gggccgaccc caccacgatg gagttcctcg cccagctcgt
     5941 tcgcgaggcg cccgcggtcc ccatgtgcat catcatgacg gctcgcccgg agttctctcc
     6001 gtcgttctcg acggccgatg tgctgctgct ccctctgagc cgcctggagc gcccgcagat
     6061 ggaggagatg ctcaccgggc tcctgggcaa caaggcgctg cctcccgccg tgatcgagca
     6121 ggtggcggac cgcgccgacg gggtgccgct cttcgcggag gagctgctcc ggatgatggt
     6181 cgactcgcgg ctcctggtgg agcaggagga ccgctacgac ctcacccggc cgctctcggg
     6241 cgcggcgatc ccggggacgc tgcgggcgct gctcacggcg cgcctggatc ggctcctgcg
     6301 cgccaagcag acggcccagc tcgcggcggc gctgggtcgg gagttcagcc tcaaggtgct
     6361 ctccgccgcg agcccgctcg gcccggaggc ggtggccgaa gatctggagc gcctgatgag
     6421 cgccgggctc gtgctgcgca agcggcggca gaaggatgcg gtgggggtgt tcaagcacgc
     6481 gctggtgcgg gacgcggcct acgagtcgct ctccacgggc gcgcggcgga ggagccacgc
     6541 gcggatcgct gcgacgctgg aggagcggtt tccggaggtg gtccggatgc ggccggatct
     6601 gctcgcgcac caccacgcgg cggcggagca gatgcaggag gccatcgggt acgcccggaa
     6661 ggcggcacat caggcgctcg ggcgctccgc ctacgccgag gccagcgcgc acgcctccaa
     6721 cgtcgtcggc tggctcgggg cgctgccggc cgccgagcgg gtggaagccg agctcggcgc
     6781 caacagcatc cggttgcagg ccctgatgtc gacgcagggc tgggcctcgc ccgacgtgcg
     6841 tgcgctggcc gagcagtccc gggcgctgct ccccgggagc aagacgaccg agcacaccgc
     6901 ctccacgctc ttcggtctgt acatgcacta ccacgtggcg agcgagcgcg cggcgtgccg
     6961 gcaggtggcc gacgagctcg tggcgttcgc cgaccggatc gaggacccgt ctctccagtg
     7021 cgtggccgcg acagcccagg gcgtcggctt tcacgcggaa gggcggtttc tggacgccga
     7081 gacatggttt gacagggcgc tcgccctgta cgacccggcg cgcgactggc agcagggctc
     7141 ggccttcggc atggactgcc gcgtctgggc tgcgggtcag ctcgcgtggg tgcaatgggg
     7201 tatggggcgg acgacgcggg cgtttcagct cgcgaacgag gcgatcgcct gggcgcggga
     7261 gatcaagcac gtcccgtccc tcgggatcgc gctgctctac ctcggccaga tccagcacat
     7321 gaacggcgac aagcccgcgg tgcacaggac gacgggcgag ctgctcgcgg cttccaaggc
     7381 ctacggcctg cctgccttcg agggctacgg cgcggccctc gcgtcgtggg ccgcggggga
     7441 cctgcagggc gtcgaggcga tcctcgggac cctcaagtcc ctccactgca acctggcgct
     7501 cacctactac gggtcttttc tggcagacat cgaagcagac gccggccgcc tgcaccaggc
     7561 gatcgcccac gtggagacct gcctctcgat gtgcgccgag ctcggcgagc gcttcttcga
     7621 ggtggagctc ttgcggcgcc gcgcgcgcta cgagatacgg ctcccggagc ccgatcggga
     7681 cgccgtccgc gagctgctcg cccgggctcg ccagctggcc ggcgagcgag gcatgcaccg
     7741 cttcgaggcc gcggcgatcc aggagcatcg gcgtatcttc ggggatgacg ccgcgctcgt
     7801 gcgccgattg acgcagctcc acgaatcgtt tcctgatctg aaattgcttt caccgaggag
     7861 tgaaccatga caatcgagcc ctccaaagca tgggagaacg gcggaacagg cagcgccgcc
     7921 ccctttcccc gcctgcgcac cgcctacctg cgagccatcg ctcgcgcctg gcgcgacccg
     7981 tccttcctgg agcagctggt caggaagtcc aaggacgacc cttatggcgt cctccccttc
     8041 ctcgagaagg aatatcgctt caggttcccc ttcaacgtga aattcgccat ctccgacgat
     8101 cccaggccgc agtggcggcc gaacgagatg cttggctggc tcgccgacgg tgacgagatc
     8161 gacatcacct tgccgggccc tccggcgctg cgcaaggtgc gcgtccacga cgactccttg
     8221 acgacgctcg cggacgccat cgccctgtat tgccagtggt tcccgtccat gctcggtccg
     8281 ccgagggacg gggtaagcca gccgcccgat gatttcgccg agttcggagt gctcacggcc
     8341 cgcctcctcg cgatgatgtg gggcgatgag aaattcaaag agcagctcct cggcgagagg
     8401 gacgctcggc gcctcgtgca agcagcgatg ggcgtcatcg tccactggaa cttcaatctg
     8461 aagttctcct acctcgactg ggacgagttc tggaacgaca tcgattatca ggggcaaccc
     8521 gagggcacga tccccgctcg ggtgaagatc accgtcaaca tccctcagaa tcccccggac
     8581 gatgccgtct ggccggtcgc cctcgccgcg tacaacgaca cgggtcccca gtaccccttc
     8641 acctgcgcgt gacctcgcga cgccgtctgg acggggagcg gagcggacgc tcgcgcgatc
     8701 ccacgccgcc ggacgagcgg cggcgcgtcc tctgcaccgc atggcggtcc gaacatctac
     8761 ttgtaggaag acggtagcgt gcgcaacggg attgcgatca tcgacatcga ccgccacgtc
     8821 atggagccca tggggttgtg gccggagtac ctgccggcga agtaccgcga cgtcgcgccg
     8881 gacgtccgcc ccctcgcgcc gccagacgag cccctcgggg ctcgcctggc ccggctggga
     8941 gaccatgccc tcttgccgac cccgccggtg gtcacggtcg gtgggaagcc catctgccgc
     9001 gggatgaccg aggtgggcta catcgaggtc gggctccacg cggaggagca ccgccgcgag
     9061 ctgatcgcgg cggagacggc ggccggccag ctcgcaacga tggacgcggc gggcgtcgac
     9121 gtcgccgtgc tgcacccgac ctacacgggg tttctggtct atgacgagga gatcgacgcg
     9181 gaccgctccc gcgcctatgc gagggcctat aaccgctggc tcgcggacca gtgccggcga
     9241 gacccgaccc ggctcaaggg ggccgcgctc atctcgcgcc acgaccccgc gcagatggtc
     9301 gcggacctcg acgccggcct cgcggacggc ctcagcgccg ccgtggtccg gccgaacccg
     9361 gtccgcggga ggaccctcgg cgcgccggag ctcgggccct tcttcgcggc ctgcgaggcg
     9421 aacgacatcc cgctgctgct gcacgaaggg acgcacacgc gcgtgcagac ggccggcgcc
     9481 tcgcgcttcc agacgcactt cgctcagcat gcctgctccc acccgctcga ggcgatgatg
     9541 gcgttcctcg ccctgctcga aggaggcgtg ttcgagcgcc atccgggcct ccgcgtcggc
     9601 ttcctcgagt cgggctgcgg gtggctgccc tactggctct ggcgcctcga cgagatcgag
     9661 tatgcgcagc tgagcaacga ggtcagcggc cgcgtgaacc ggcgcccctc gagctacttc
     9721 cgccgccagt gctggatcgc cttcgagccg ggcgaggcga tgctcgcgca cagcgtcggc
     9781 gccatcggcg aggatcgcgt cgtcttcggc acggacttcc cccacgtcga ccacgatccc
     9841 acgatcgtcg ccaggttgtt cgacggcggc gcgccgctcc ccggcgaggt gctccgggca
     9901 gccctgtggg acaacccggc gcggctcatg gggctgtcgg aagcggcgcg cccgcgcggc
     9961 gcgtgaacga gcgcgaggcc gacccgcgga aggaccgacg atggacgctc tggagctgag
    10021 ccaggtgctg gcgtggaagc ccaccttgcg tgtcgagcgc gccgatgacg gcgtggtctt
    10081 cctgatcggc gagcgggagc gcttcgtcct ctccggggca cgtatggccg aggtggccat
    10141 gctcgtcgac ggccagcgca ccgtggacga tatcgtgtgc gccgtgcgcc ctcggatctc
    10201 cgagccggag gcgctgtaca ccttgagcgg gctcgcggcg cgcggttatc tggtccccgc
    10261 agcgccagag ctcccctccg agcgcgcggc gttctggcgc ggggtgggcc ttgacggcga
    10321 ggcggccgcc gaggccctga gccgcacccc cgtgtcggtc ctggccctcg gcgaagccgc
    10381 tgccgccggg tggatgaccg aggcgctcga acaggcgggc gtgcggatcg acggcgaggc
    10441 ggccgtgcgg gtggtcgtga gcgacgaccc cctgcggccc gagctggcct cgatcaaccg
    10501 ccgcgcgctg cgcgaaggga cgccctggtt cctgatcaag cccgccggcg tgcagccgct
    10561 catcgggccc ctcttcgagc caggcgccgg cccctgctgg gactgcctgg cgttctggat
    10621 gcgccagaac cgcccggtcg aggagctctt gcgccggcgc cgggggcacg agcgccacgt
    10681 cgctcccccc agggcggcca ccgaggcgag cgtgcggacc gcctgcgggc tcggcgccct
    10741 ggccatcgcc cgcgcgctcg ccagggggga tacaagcgcc gcccatgcgc tcagctcccg
    10801 ggtgctcgcc ctcgacctgg ccaccttgca gaccaccacg cacgcggtcg tccggaggcc
    10861 gcaatgcccg acgtgcggag atccggggcg gatggcggcc gtcggcgagc gcccgatcga
    10921 gctgcagccg gtcgagaagg cgcattacga ggacggcgga taccgccggc aggccccgcg
    10981 gcggacctac gagcgttatc agcacctcgt cagcccgatc acgggcgccg tgacccacct
    11041 cgtgccgatg ccgggacggg acaccgagct ccgcgccgtg tacgcgtccg gttacctggt
    11101 ctgtcctcgg gacggcgtgc cgcagaccaa cgtcttcgac aagggctgcg ccggcaaggg
    11161 gcgcggcgcg gaccaggcca gggtgagcgc gctctgcgag gcgctcgagc gttacagcgg
    11221 cgtataccag ggggacgagg cgcgcgtccg cgccagcaag aatgagctcg gcgcgtcggc
    11281 cctggcggcc ggcgatctgt tgaacttcag cgaggcccaa tatcgcgcgc gcgatcggct
    11341 caacgcgcag gcggcggatc gacgccagcg ggtgcccgag ccgtttgacc ccagcgtccc
    11401 gatggactgg actccggcct ggtcgctgag ccggcgcgag cggcgttatg tgccgctcgc
    11461 ctactgctac gccgaggctc cggccgagag cggcgccgcg ttctgcggcc cgtccagcaa
    11521 cggcgtggcg gccggcacct gcctcgagga ggccctgttg caaggcctgc tcgagctggt
    11581 ggagcgcgac gccgccgcga tctggtggta caaccggctc gctcgcccgg ccatcgatct
    11641 cgatggcttc gcggatccgt acttcgaggc cctccaggcc gactacgctc gtctcggctg
    11701 ggccgtctgg gtgctcgatc tgacccacga cctcggcatc cccacctgcg tggcgctcgc
    11761 ccacgaggcc cgggcggatc ggttcgccct cgggttcggc tgccacctcg acccgcgcct
    11821 cgccgtgcag cgatcgctca ccgagctgaa ccagctcttc gatcccgccg gcgcccgccg
    11881 ggcgccgtgg gacctcgagc ggctgcccga ccgcgtgtac ctcttccccg accccgagct
    11941 gccgcgggtc gccgccgagc gcctgccgcg gctcggcggc gccgatctgc gcgccgacat
    12001 ccaggaatgc atgaggcgcc tcgacggggc gggcctggag ctcgtcgcgg tggacaagac
    12061 ccgccccgac atcggcttgc ccgtggtcca ggtgatcgtc ccggggttgc gccacttctg
    12121 gcctcgattc ggcccgggga ggctctacca ggtgccgtgc gcgcagggat ggctggcccg
    12181 cccgctcgac gaaggcgagc tcaatccggt ccctctgttc gtctagccgc cgaggcgctg
    12241 cgccggggcg cgagggggca gggcggccgg acgcccgccg tgtcccgaag ggacgcagcg
    12301 cgtccgggag ggacgcaggg ccgtcgagaa agaaatcctc gcgaggccgt cgtccccctg
    12361 tgcccctctc tcggcgcgcg cacgcagggg catccccgga agtccacctc agttttcatg
    12421 ggtggcatac gttgtgctgg ttcacagcgc tgaccagcaa gaggccaccc tgttcgggtt
    12481 atcagctcat acgaggagaa gaggagagcc tgtggaaagg aacactgtgt cacgcgcttg
    12541 tcgtggaagc tcaatgaagg gacgcacccg tgcgcagagc accgcgcgtc gtcgtccgat
    12601 cgccgtcgca gcttgcgtcg gcctgttatt gaccttgctg gccgctggcg gcgaggccgt
    12661 cgccgccccg gtcacggtca ccaacggagt gcagttcacc gacaccgccg gcaacgtggt
    12721 gcgcgggcac gacggcggca tgatcaaggt gggccagtac tactactggt tcggcgcgaa
    12781 cccccactcc gacaacagat tccagcacat ctcggtgtat cgctcgaccg acctgcatac
    12841 ctgggagttt cgcaggcacg tgctgaccga ggcctcggcc cccggagtga agaatctcca
    12901 gcggcccaag gtcatctaca acgcccgcac ccggcagttc gtgatgttca tgcgcaagga
    12961 gaaccaccca caccccttgg aggagaaccg ggtcgggatc gccacgtcgc ccacggtgga
    13021 cggcgactac acataccggc gcgacttccg acccctcaag gaaccctcct tcgacgtgag
    13081 cgtgttccag gatgatgatc gcgaccgcac ggcgtacctg atctcgacga ccggtaacga
    13141 ccagcagcac ctcaccatct accgcctgac ccccgactac ctctatgtcg ccgccaggga
    13201 gctcgttctc tccaacgtca cccgggaagc gcagacgatg ttcaagcgcc acggcgtcta
    13261 cttcctgttg acctcgggcg tcaccggctg gcagcccaac cagaccaagt acgccaccgc
    13321 gaccagcatc aaaggccctt ggagcgccat ggcaaacctc ggcgaccgca tcacctacgg
    13381 ctcgcagccc acgttcgtcc tgccgatcca gggcagcaac acgacctcct acctctacat
    13441 gggcgaccgg catgggaacg cctgggacgg caacatcaac gacagcgagc acgtctggct
    13501 gccgctccag ttcccgacca acaggacgct gtcgatgcgc tggcacccgc gggtctccat
    13561 cgacaccacg accggcgagg tgagcggcgt cggctccgga cccgcgtacg aggagctgcg
    13621 accccagcac aagacggacg agtgcctggc tgtgcggcgc ttcaccaatg gctccgtagt
    13681 cgatgacagc caggcgaatg gcaacggggt aggggtgatc ctgcgaccct gcggctccgc
    13741 cgcgacccag aaccagcact ggcaagtgct ccacctggga gccggctacc accggatcgt
    13801 cgcccggcac agccacaagt gcctcaccgt gccgtcgtcg tccaccgccg acgacacacg
    13861 ggtgacacag tcgacctgcg gcaccggcga gaaccagcag tggaagatca ccgacctccc
    13921 cggaggcgac ttccggatca ccgctcggca cagcggcaag tgcctgacca tccgctacga
    13981 tccggacatc aagggcggga aggccatcca gttcacctgc gagggcaccg ccaaccagcg
    14041 gtggaagcga gccggcgccc cctactcacc ctagggccaa tgccgcgtcg aaccggcggc
    14101 ccggagctgc gaaccattga tctggctcgg cagcgctccc cgctccccgg cggcaggaac
    14161 cggagcgccg gcaggagcgc cgggcgagcc ccctcctcgc tgctaccgcc gccgttcggg
    14221 cgatgctcga cgccgcggct agctagcggc ctcgggcgcc ggcgacctcc ggggcgccac
    14281 cggcggctgc tcgggttgcc ggtggcaccg gaggggcgag cgagctcggg ccggtcgtcg
    14341 agcccgccgc tcgcgtcgac tggctgccgg agcctcgccg ctcgccggcg cccgcaggct
    14401 ctgctgcgat cgcccacgct ccgtgtgtgc tgccgaagcg cccctgaggc ctccgggaaa
    14461 gcggggacat cggggatcgg gccccagctg gacttcttgt cctccgtgcg gtaaggctgc
    14521 gtaaacgacg ctgggggtgt atccggatgc atgaggtgaa ggggaacacc cagacgcgac
    14581 cgaacttctg ctcctttctc gtcgtcgccg ccaccctcgc tgcggcggca ggatgctccg
    14641 cgcaagaccg gcgtttctcg gacagcggaa cgggtggcgg ttcgatcgat gcgcagggcg
    14701 gcggaggcgc cggcgcgtcc ggcgggggcg gcgcgggcgc gtccggcggg ggcgcgtccg
    14761 gtggtggggg cggtggtgat cctggatgcc agatcccgcc agacagcccc acgctcgccg
    14821 acgccatcat ggtggctgcg ggcgacagcc atacgtgcgc gatccggcat gacggctctc
    14881 tctactgctg gggggacaac tcgttcggcc agctgggtgt tccgcaggcg atggcggtct
    14941 cctcgagcac gccggtgaga gtgcttttcc ccgcgtcgct cggcacggcg acgatcacgc
    15001 agatcgcgtt gaccgagcgg gcgaccttcg cgatcgacag ccagctccga ctctgggcct
    15061 ggggaagcaa cgagaccggg atcctcgcga acggctccaa ggactcgatg gcccatgacg
    15121 ccccggcgat cgtcaatgac ggtacggccc cgttgctcgt gcgcaagatc gcgccagcgt
    15181 ggtactcggc gtgcgcgctc acctcgacca gcagcattta ctgctggggg gccaacctgt
    15241 tctcgagcct cgggccggat gcgagcggcg aggagagcct cgtcccggtg agagcgttca
    15301 acttcaccgc gacggccggt ccgagggcca tcctcgcgcg gggcatcggc tcgataggca
    15361 gctgcttctc gaccgggacc gcggaggacg ggctgcgttg ctggggcgcg atcggcggcg
    15421 gttatatcct cacgaacacc tccgccagct cccagggcgg cgtgaactac agcgcgcaca
    15481 tgccgctcat cgaggcggga gcgacgctgc ccttctccga gatctcctac ggcacgaact
    15541 tcggctgcgc gcgcgacgac gtgggaggcc tcttctgctg ggggacgaac aacagttcgg
    15601 gtcagcacgg cgccgaggct cccccggccg ggacggcggc tgcgatcccg ggtgtctggg
    15661 gtccgatgtc caccggctac gtcttcgtct gcgcgatcga cgaccaaagg cggctccgct
    15721 gccgtggcag caacgagcaa gggcagctcg gtcgcagcac gccgatgatg ggcgataatg
    15781 cgcgaatgga acctgtcgtg ctcggcgacg gcaccgcgct cgccaaggtc gtcgcggtga
    15841 gcgccggctt cttccacacg tgcgcgatcg tcgagggggc gtgcggcccc acgggccctg
    15901 gccaggtcct gtgctggggc agaggcaccc tgggtcagct cggcgacggc gccgggacga
    15961 gctccgcggt ccccgtcgag gtgaaggcgc cttgagcgca ctctcggaca caggccgcga
    16021 cgcgccctga acggccgatg tcgcggcgca ccggccggtc agggtgcgat cccctccgct
    16081 tgcgcgcgtg tggctcctcg agcgcgggct cgacgctgcg gcctggtcgg atggcggagc
    16141 ggccgcggcg tcgaggagga tgccggcgag ttcggagcgg ccgtgcaggt cgagggcgac
    16201 atcgggcgct ggtgactgga caccggcgct cagcgccggc gagctcgggg ccgtcgccgt
    16261 ccacctggcc gaactcggcc acgtctgccg ttcgcgggtc tgaggggagg ttgagatgat
    16321 cgaggatgcg gcgcacggcc ttcgggtccg tgttcgtgga aagcgcgcgc atcttccgtt
    16381 cgcacctcgg ccatcgcaaa gcatcgaatc cgaaggtgcg ttccatgagc acggcccact
    16441 cgacattgcg cgacgttgcg atctcggcgg gttcgggacc ggctgcgtct cgtcgtggtg
    16501 gaacccgcgc aggaccagcg atcccgtcac caagatcaac atcgacggcg gcaagcgctg
    16561 gagcgtgcgc gacagctacc tgacaccctt ggcctcctga cggcggtcct cgccgcgttc
    16621 gccctccggc gacgacaggc ctcctcatcg cggagcgacg ccagttaggt ggacagcgcg
    16681 gcgctgctga agtgggcgat cgagaagcgg cagccgaacc ggttgcagct ggagtcggac
    16741 cgagccgtcc gcccgcgccc ggcgtgggaa ttccccttgc ggcgcgggtc ggccatactg
    16801 cgcagcatga cgaagggaag ctgcccatga ggaccacgcg ctccatccgc ggcagcgacc
    16861 atgcgccggt gcagcggatc acgcacgtcg cctatggtga cgacacgcag gaccagtccc
    16921 tgcccgacgg ctgctgggac ctcgtgttca tgaagcgccg cggccggctg caggtgctgc
    16981 ataccggtct gatcacgcac ccggtgacgc tgggctgcga gaccggcgac gagtacctga
    17041 gcatcgcctt ccggccaggc gtgttcatgc cgggggtgcc ggcgatgggc atgctggacc
    17101 agggcgtgct gcgcccgctg gcgaacccgc gctcgttcct gctggggccg cgagccttcg
    17161 aggtgcccga cttcgagaac gccgacgatc tggtggcacg cctcatcggg gccggcctgc
    17221 tggtggcggc cccggtggtg ttacatcgtg cgctggaccg agctggcgcg cggcgggcat
    17281 ttcctggcga cggagacgcc cacggcgctg gccgtcgatc tgcgggagtt cttcggttcg
    17341 ctgtcctagg gccagcctgt ccacgcgact tgcgcgccca ccgtgacgcc ggcgcgcccg
    17401 ccgaacttga cacagtgtaa actgtgcccc atgcttgaca ccatgtcaag taaggacggg
    17461 gaaacccgca ctgcgatcct cgaggccgcg cgccggctgg tgaccgagcc ggggcgtcgc
    17521 ggcgtctcga tggcggagat cgcgtcggcg gccggggtgt cgcgccaggc ggtctatctg
    17581 cacttcgaga ccaggaccca gctcttggcc gcgctggtgc gtcacgtcga cgaggtgcat
    17641 gggttcgccg acctggtccg gaagtgcgag cgcgcccccg acgcgcgcgc gatcctctcc
    17701 gagttcatcg gtgcgtgggc gggctacgtc gcccacatca ccgacgtggc gcgggccatg
    17761 caggcggcac gggccacgga cgaggacgcg gagctcgcgt ggcgcgaccg catgcgcggt
    17821 ttcacgggcg tctgcgcgcg cttcgtggcg cggcttcagg ccgaaggcgc gctggccgac
    17881 gaatggtcgg cgtcggatgc ggcggacttc ttggccacca tcctgtcgat cgggaactgg
    17941 caggagctca tcgaggagcg gagctggtcc cggccgcgct acgtccgcgc gatgcgtcgg
    18001 agcgtggagc agagcctgct caggccgatg gagatcgaga cggcgccgag gaggcgctcg
    18061 tgagcggcgc gcagccggag cttttggcgc agggctcggt ggatatcggc cggcccctgc
    18121 acgaaacgtt cgcgtacgtg tccaacatgg agaacttccc gacttggttc ccgggcgtcg
    18181 cagccatgcg cgagctcgac acgctggagc acgggcaggt cggcaagcgg tatcgggaga
    18241 ccgtgcgcat gcccttcggg cgcaccggca cgatcgacat cgaggtgaag gaggcgcgcg
    18301 tcggggagcg tctgctgacc gaaggtgagg gcttcctctt gccccgcatg agcgtgggct
    18361 tcgcggcgct ctccgacggc gagacgcgcg tcgagtggcg catggtcagc cgcaatcagc
    18421 ggtggtggtt tcgctggctt gtggtcccac tcctgcgccg cgtgatgcgc ggccgagcgc
    18481 gcgacggact gcgtaagctg cgcgagaacc tggagcgcga gccgtcgtga atggtgccga
    18541 cgttcgagcg cacctcgcct cgggctcgag ctgggttggc ggacgttgcg tcggcgcggc
    18601 gggcgcttgg ccctcctccg gcgcttgctc acccagccct ccgcgttcag ccggacaggc
    18661 gggcatcgag cagctgccgg gatcacttgg cggccagggc gggagtcggc ccgactatcg
    18721 acccgagttt gctcgcctat cggccggagg cggcgccgct cggccggaac gtcggaggtg
    18781 ccggccggcg cctcgtcgtc acgctggaag cgagccgaag agcgacgccc atacggcgcg
    18841 cgtccggacc gtcagcgcgc tggccggcgg cacctcgatg gcgtcgtcgg ggacgagcac
    18901 cttggcgtag atcgcctcgt acacccgctt cacctcaccc ggccggacca tgtcgcgatc
    18961 gtgagccggc atgatcccga ccagcctgta tctctgccgt tcggccagga cctgctgatg
    19021 gggtgatttc aacgtcgcga agtagtacgc gagctctgct ccgatcgcgc gcccgagcct
    19081 ctcgagtagc atggggccga ggagcgcgag ggacgggccc cgatgcgccg gagcgatcgc
    19141 gcccatccgg cacgtgatgg tcctcgcgct cgcgttcttc tcgaaggtgc tcatcgccac
    19201 gatggcgccc tggtgcctcg cgacgatcgg gaggatcggc cggtcctcgg cgacgtccgc
    19261 gagcatcgtc tgctcgtagt agaactccgg cgtcaggtgg catgactcgg cgccgacgac
    19321 gatgtccggg taccacccgc ggaggtcctc caccagcgcg aggacatcgg ctcgccggag
    19381 ctgcaccagc tcgtagccgc tcggtacctt cgtctctttg agcgcggcgt gcgctccgtc
    19441 ccagttcatg tgacatgccc ctcggtcaat tgaaccgttc tttgttgaag gagatacgga
    19501 ttccggctgg acccagccgg ccacgcgagc gccccgcgcc tgtcgagctc ttccctcgtg
    19561 ccggagctgc cctgcgggta gaaacgcagg cgcgacgcgg agtcaagcgc ctcgcccggc
    19621 cgcggccccg gcgcgccggt tcgcgggagg gcgcccgcgt gtgatgcacc gccgcttcga
    19681 tgagctccga gagcgaatcc gtcggtgcag gccggccgtt caccgccgcc gagctcgacg
    19741 cctgcctgaa ggtgctcgag tccctggtcg ccgatcgcgc gctgctcgcg tcggtcagcg
    19801 cggaggaccg ccgccggctc ctgctcgccg ccggccgcgt ctcgcgcctt gagcgcgccg
    19861 tgcagcggga gctcgcccgg gcgttccgca aggacggatt tgcggtgcgg ccacgtaccc
    19921 cggctaccag ccgatcccgc cggagctcgg gaacgaggtg gtgccggatg tggacatgga
    19981 cggggtgtcc atgggcgagg cgacgatcta cgtgtgcctc ttctcagtcg tgtggacttg
    20041 gttggatccg gtatagccct tccctggcgt ccgccgtcca cgtggccggg ttgggcgcat
    20101 agacgacgag gagctcgagg cgagctcggc ggcgcccctc cgcggcggcg cgaccgtggc
    20161 ggcacgcgcc ggggagagct cggcggctcg cacctcggca ggagatcttc ttccccacgt
    20221 agaagcgccg cgcgagctcg gggccgtcgc cgtccacctg gtcgagctct gccacgtcgc
    20281 ggcgctgaac gcccgcgagc tcgcgatcgc gcttgcctac acggcgcccg cgcagatagt
    20341 ggggccgcga cgtcgttcgg ctcgctgcgg cgtactttcg tacgcctcac tcgcctgcct
    20401 agcggctgag ccagtattac acggatctgc acctcgctcc aattgccgga ttaacgcgta
    20461 tgtttggggc ccggcgtgag gatgctatcc gcgcccggcg cgcccgtcca gaggtacagg
    20521 cgcgcttcgt gagcagcgcg cggcgccacc tcgaccccgt cgtgggtgcg ccgatcaagg
    20581 acggatcacg cagccgccta cttgttggaa tcgagccgcc tctgctgggc agctcgctct
    20641 cgtgcccggc cttcggccaa ccagcaccgg gcgaagatga taggtgcaac aactaagccc
    20701 aggacgacca ggccgcgtaa ccacacattg ccgtggggat cacgcgttgc gctttcgtag
    20761 ttcatcgcgg taaagagaag ccacgaaccg gacgctacaa tgccggtgat ccttagggcg
    20821 gggctcatcg ctttccaatc ctctaccgat atgctcaaaa ggctgcacac atcaggccca
    20881 gaccgaaaaa tcctccgccc gtccagtagt cgcagcgcct cctgtcccgc tccgtcgtcg
    20941 cacgcgggca caggagaaac tgcgagacca gggcagatcc gcccacgaag tccgcgcagc
    21001 ccaaagagaa cggcgaaagc cgttgttgcg cctccccggt cccgttgtcg ttcgggtcgc
    21061 ttgttggagc gctgcacgcc tccccgatgt cgttcagaat ggctgagcac ggcacgtcac
    21121 tgtagtcgcc cagcgcgagc gggttgaaca ctcgtattgc tgcaccagaa gtgctcgcgc
    21181 aggctgcggc gatctcttcc cgtcctgcgg caacgatccg cgggatgacg gtctcttccg
    21241 tcgtatcgct ggatagctgc acatcgaacg ttcgcagcac gccctcgttc tcctcctccg
    21301 tttcggactc ccccgtttct ccgtggcggg gcgtcgtctc gactgtgcaa tcggtgagca
    21361 tcgccccaca aacgagcagt ccggccgatg tagtcgtcct gcacatgccc acctccgtcc
    21421 aggactgatg cgagggccgg accagcacgg cgagcgcgtt gtgcggcaag catcacgatc
    21481 cccggcctgc ggctcctccc gggcggaggc gctcgcggcg gccgccctcg gcccagtgca
    21541 gggggtgggg gccaccgagg acgagcgcga gatcgtggcg accctttcgg cgcggcggcg
    21601 cggtggggcc agagcagcca cggccaggcg cccgcggacg tcgcgagcgg tagcgagctg
    21661 gccggccgcg aggagctcgc ggagccgcgg agcttctcgg agagggccgc cggcgtcggc
    21721 cgccaagacg gccgcacctc gagggctatg tcgggcgctg gtgactggac accggtgctc
    21781 agcgccggcg agctcggggc cgtcgccgtc cacctggtcg aactatgcca cgtcgcggcg
    21841 ctggacaccg gcgagctcgc catcgtagat ggcacccgag cggaggacga ggccgcggcg
    21901 tcgaggagca ccgcgacgtg gtccgcacct tccggcggac cggagggggt ggttgatgaa
    21961 aggatgggct gcctgatgaa aagagcgtgt tctcccgggt gcggcgcggt ggccgtcgac
    22021 ttcagctcgg atcccctgga ttgggtgtgg gtcggcgtgg ccctgctcgt gctcgtcggc
    22081 atggtcgccg cgctcgtcct ccgcttccgg cgccgtcgct gacctcgaag gccagctgta
    22141 cctcgcaggc ggcgccgctc gcttggggcg gcgccaggcg ggggagcggc tgcgggggcg
    22201 aggtgaacgc ccgcaagcct taatcg
//
