LOCUS       NZ_CP012673            23733 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Sorangium cellulosum strain So ce26 chromosome, complete genome.
ACCESSION   NZ_CP012673
VERSION     NZ_CP012673.1
KEYWORDS    RefSeq.
SOURCE      Sorangium cellulosum
  ORGANISM  Sorangium cellulosum
            Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae;
            Sorangium.
REFERENCE   1  (bases 1 to 14557589)
  AUTHORS   Zaburannyi,N., Bunk,B., Overmann,J. and Mueller,R.
  TITLE     Sorangium comparison
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 14557589)
  AUTHORS   Zaburannyi,N., Bunk,B., Overmann,J. and Mueller,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-SEP-2015) Department of Microbial Natural Products
            (MINS), Helmholtz Institute for Pharmaceutical Research Saarland
            (HIPS), Campus E 8.1, Saarbruecken, Saarland 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SMRT portal v. 2.2.0, HGAP v. 3.0
            Genome Coverage                   :: 134x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002950945.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 11:58:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,531
            CDSs (total)                      :: 10,457
            Genes (coding)                    :: 10,397
            CDSs (with protein)               :: 10,397
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 6 of 60
            Pseudo Genes (incomplete)         :: 58 of 60
            Pseudo Genes (internal stop)      :: 2 of 60
            Pseudo Genes (multiple problems)  :: 6 of 60
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:39:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 630720
            Orig. end                         :: 654453
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012673.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from German Collection of Microorganisms and
            Cell Cultures GmbH, Inhoffenstrasse 7B, 38124 Braunschweig,
            Germany.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23733
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23733
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23733
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13733](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13733)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(129..143)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.1"
                     /tool="antismash"
     misc_feature    129..147
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.97"
                     /tool="antismash"
     misc_feature    complement(137..150)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.43"
                     /tool="antismash"
     gene            complement(310..1257)
                     /locus_tag="SOCE26_RS02545"
                     /old_locus_tag="SOCE26_005070"
     CDS             complement(310..1257)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015789.4"
                     /locus_tag="SOCE26_RS02545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005070"
                     /product="hypothetical protein"
                     /protein_id="WP_159396608.1"
                     /transl_table=11
                     /translation="MIRLGYVCQSLGMPEPSLRTAQLGRYLKGLVELTPIYTYNAEYVR
                     RSIAHSAALGLTAHRISSDLFPLLDIAPGARMLVPDLRAVRRAAAHGDVHLSNHPSQFV
                     VLSSPREEVLQNSLAVMDDQGWVMDLLGAQGSITLHGGGVYGDRESTAARLREGIARLT
                     PAARHRLALENDERCWTVPELLEATGGEVPIVFDNLHWAANPRSAPYEVELEGALRTWP
                     AEQLPELHYSEQWKGKPSGAHAQHITGRGLLRFCEEVDEASDRREVVVIVEAKQKDLAI
                     LRALGELTSRQRARLHTLVPGLAAAAAPQRACLA"
     misc_feature    1288..1301
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     misc_feature    complement(1305..1325)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.33"
                     /tool="antismash"
     gene            1315..2379
                     /locus_tag="SOCE26_RS53350"
                     /old_locus_tag="SOCE26_005080"
     CDS             1315..2379
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013528.4"
                     /locus_tag="SOCE26_RS53350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005080"
                     /product="DHH family phosphoesterase"
                     /protein_id="WP_234023316.1"
                     /transl_table=11
                     /translation="MPSSEQSSLARQTARDLLCRAGAQRSRVAIVYHADADGTSSAALA
                     CFAARALGAEVVPETPDKGENVHSPAFGARVRATGAALAVVLDTGSRPGRLFEVPTVIV
                     DHHRADPAEAPEVEAFVSTFGDDRGTSTSALTFELLAPIAPIAPRAWLAALGLLGDLGD
                     VARRHPLVAAAARQHGFTALREAVSLVNAAGRSAAHDAGVALAALLEAERPADLARGDG
                     EAARRLRALREDVAAATRRAIRAAPRVYGRWAVIELDEPYRIHGPVASAWTRRMEGRIV
                     LVANRGYVPGRVHFSVRSHEPIDLRAALSALLPDAGPDVAAGHDRATGGIVEVPVFEEL
                     LRRIQGEAAQGAAA"
     misc_feature    3098..3107
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.44"
                     /tool="antismash"
     gene            3369..8333
                     /locus_tag="SOCE26_RS02555"
                     /old_locus_tag="SOCE26_005090"
     CDS             3369..8333
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012241162.1"
                     /locus_tag="SOCE26_RS02555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005090"
                     /product="AAA family ATPase"
                     /protein_id="WP_104977141.1"
                     /sec_met_domain="Pkinase (E-value: 4.1e-37, bitscore:
                     127.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVELVNHELVDTLHDGSRSSVYLGRSKSTGKLCVIKVARKGANGT
                     RNIAILKRQYEITRRLELDGIVKVHDLEVRLDYAALIMEYFAGRSLRAVIDDGGNGVGL
                     VPATRIALQLAATLGAIHERNVIHKDIKPSNIIVDDAISTSKITDFSIASLLPGEQATV
                     YDPWTAGEGTLQYISPEQTGRMNRSVDFRSDYYSLGVTLYELTTRHLPFEATDPMELVH
                     FHIAKTPVPPHQVRQSIPEALSKVIMKLLAKTAEERYQSAFGLKADLETCLKIIQTGEP
                     SSDFVPGRQDRPTRLQISQRLYGREDEVDTLMEAFRSVSEPGAGGARSGQSELVLVAGY
                     SGIGKSAIVNEIHKPIARQGGYFAAGKFDQFTRNIPYASIIAALREIVRQILTESKEEL
                     ADWKARILASVSPNGQVIAEVIPEIELIIGKQPPVPSLGPIETRNRFNLTFRSFIGAIT
                     LKTRALVLFLDDLQWADTGSLNLISVLMEDPDIRHFLLIGAYRDNEVDDAHPLMMMLSS
                     LGKAKTRVRTVALKPLAHEHVNQLVSDSLGTGQEECHLLSELIHTKTDGNPFFAVQYLT
                     NVYREGHLSFNSEHGAWQWNASGIAKMTATENVVDFMVRTIRSLGETTQRVLKYAACIG
                     SQFELKLLAQLNGTDLRSTEEYLWAALEVGLIVPVDGDYRIVRFLDDAEESCAVYKFSH
                     DRVQQAAYRLLAEGEQQRAHLMIGQLMLQHTPPESIEERIFDIVSHLNLGAPLVVDVDS
                     RYRAAALNVKAGQKARRSTAYGPGVQCLRAAAAFLPEDSWQTNYELSLCVYTDLTELEY
                     LTINFERAEEAARVVVNQAKDPLEKIRVYETQIQFYISQNRMLDAIDVGMSVLSTLGVT
                     LSEAPPKDFDIPQLEQLPPMTDKRMQAAIQILCTVQPAIYVAKPMLLLSNAFTMVDICT
                     KYGNSPTGAFAYAIYGSIQCNFMGNVDVGFALGRLAIDLVHRFGAVDLECKLYNAVYVL
                     IYHWKRPLKETVEPLGRAVQAGVEIGDIEYAAHSSFGYSINSFFAGIDLATVELRMKQA
                     VDLSQKFDQQFPLYHIKIWKQLVSGLRDVYAERLRLVGESFDETTMVPYLGRPSMFSLH
                     LAKGMLLYYFGESKHARDCLRSCEEYQDGAAGVVTIVEQNFYYSLSILASLDRLPKEEQ
                     EIELTKVEENQRRLEAWARAAPDNNQHKHDLVGAELARSRGAPIDAMELYDKAIEGARR
                     CGFIQEEALACELASSFYRKLGRQEIAHHYMILAYRGYALWGADAKCQSLVAAFPQLMF
                     EGAPDRTASMTGTSSHDGAALDLLSVIKASQAVASEIVLERLLENLMTIVIENVGAQAG
                     VLALVRGDALFVEAERTVEPKQVNVLKSAPISSCKKVPLSVVSYVQRTLQTVLLDNAAA
                     EPRFSEDPYIRARQTKSLMCSPILRQGRLVGVFYFENDLSTGVFTKSRSELLSLLSTQV
                     AISIENAKLYEGLEQAVAERTEELRVSNERLQAVNERLQVELAERERLQEERVQMQEEI
                     IQTQRARLHELSTPFIPITDDIMVMPIIGTIDDKRAAQMLETAMEGVATSSARVVIIDI
                     TGVKTVDTSVASRLMSLAKAVKLLGSKAILTGLRPAVAQSLVALGLDLGSIETRSNLKA
                     GIAYAMKRTATIHRHA"
     gene            complement(8366..9829)
                     /locus_tag="SOCE26_RS02560"
                     /old_locus_tag="SOCE26_005100"
     CDS             complement(8366..9829)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="SOCE26_RS02560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005100"
                     /product="cytochrome P450"
                     /protein_id="WP_104977142.1"
                     /sec_met_domain="p450 (E-value: 1e-37, bitscore: 129.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQARILSPIHEDVSTPAHGGSPSDSKNSLGGGSRGSWPVRLWRK
                     VRPCADRDDHPVAPGGLPIAGHLPRLHLDAPGFLLRSQAELGPVFWVDLGFGRERLFCV
                     GPDSLDLLRTPSVENDASDPEIKSMFGGSLVTADGASHRHMRSALGPSFSTHGLSVSGL
                     MAPLVSLIEEHIERWLSRGSVDALPEMQDLTLEIVLRLAGVPVDRLHAWKQAYRDFILG
                     LIPVPGHLPGLPRYRSARAQTWLNAELRQLVDNARLGHAQGGLLGTLTSARDENGEALS
                     TDELVHNLRVILFAGHETSASVLAWVILLLARRPDLWRSLMDEHDAQAGGPLPSSPKDI
                     SKFPIAEAIFREALRLYPPVWFMLLRTGTDIVVSGRSIKAGTPMAISPAVLGLDKTNFP
                     HPERFDAGRWTGRSRAPTPLELAPFGGGSHFCLGYGLALFEGVCLQIALARACKRRGLR
                     PVHDGAEPRPGYLPLTQPRTTARVRFERA"
     gene            complement(10001..10996)
                     /locus_tag="SOCE26_RS02565"
                     /old_locus_tag="SOCE26_005110"
     CDS             complement(10001..10996)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="SOCE26_RS02565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005110"
                     /product="terpene synthase family protein"
                     /protein_id="WP_104977143.1"
                     /sec_met_domain="T1TS (E-value: 2e-09, bitscore: 36.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAEEAKRLIREQLQAPGTGEFIRGLTATLRAELSVFGSTVSERL
                     PAAASFATLTTPPQLRSKLSRIPSYMSGWVYAMDALLDTCPSIDYADDLSSLLRRRLEL
                     PSDVQLTWLDMDLARDPTQDAPGLDYSIMDIVDGIQPLRRSLEEASPDAVGLRTFDRCL
                     IDGVVPAMCTEARWRIEQSAPTDVSEYLRTASVTICVTLCMSALNAMLPGAGERWRVIE
                     PVTAPLSGALRLMNDVATYEKDVLERKPNPVSIMMSNGVPPGRARADLRRMIDEFAREV
                     EHLCQQNIGSRSADDPTSSLSICMLHQLAAADMMYSIGDFVELKQITTAP"
     gene            complement(11006..12595)
                     /locus_tag="SOCE26_RS02570"
                     /old_locus_tag="SOCE26_005120"
     CDS             complement(11006..12595)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.4"
                     /locus_tag="SOCE26_RS02570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005120"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_104977144.1"
                     /sec_met_domain="T2TS (E-value: 7.9e-76, bitscore: 254.9,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYEGTTNPDPAAHPSIASCAYDTAWVASLPDPDRPERPRFPAAL
                     EWVFEHQRPDGSWGGEIAYEHDRILSTLSALCAITRFKGDARTTRAVESGQRYIWQHAH
                     ALSREPVELVGFELLLPTLQSRAARAGVRLPSYLDIYAEQRRRKLAMIPSDLLYSPKVT
                     IVHSLEFLGDEVDVDRLASVQWENGSVGSSPAATAFFLHKRESEAAVDYLRRCLELDGG
                     AAVPVVHPCETYDLLWSAYHHFLGGARGPGLLPEATISALRAALDAGEGISASATFPLP
                     DADDTAVAMLLLRSMGYDVKPDALSPFERDGHYASYPYERHASSGVNMHVLDTLKWMPS
                     TQERDMKIGRILTFLADTRTHGTYWIDKWHISPYYATAHALAALADLPEPHSHVADELA
                     RTALDWVRQTQNADGSWGFYDRPTAEETAYGVLALRHARRLALPGDDWRLELAVDYLLS
                     QQGAEHPPLWIEKCLYTPRNIVNAAIDAALQGASRRRVSEVRFLGTPDPLPRELAAGGG
                     SARKRGPRGGRR"
     gene            complement(12708..13733)
                     /locus_tag="SOCE26_RS02575"
                     /old_locus_tag="SOCE26_005130"
     CDS             complement(12708..13733)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="SOCE26_RS02575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005130"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_104977145.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.1e-63, bitscore:
                     214.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTTSIEGLSALRTALLDYEEVRRRYSGEVERRVMERQGAGLVHG
                     MTAYHLASGGKRMRALLPIWVCINLGGRAEDALDLGVGLELLHNATLIHDDIQDGDSHR
                     RGRPAVWFQWGVAQAINAGDALIFQGIERIARSPAARQFLPFLMDALTRIAEGQAMDLD
                     LHQRPAPAVTLKAWEAMARSKTGALFAACVRAGALAAGAEADVVESATTYGEDVGLLFQ
                     VQDDYLDIVGDKGRTHRGRDLMEGKLSFPVIWALEHGSAQAVAPVRALLECAREQRTLA
                     MVDEAVDALARCGALRATAGWIRSAAQQLEIHWMAKVLPNWGWRCLAPIAHALAADLSA
                     S"
     misc_feature    complement(13707..13709)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15006..16556)
                     /locus_tag="SOCE26_RS02580"
                     /old_locus_tag="SOCE26_005140"
     CDS             complement(15006..16556)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012232845.1"
                     /locus_tag="SOCE26_RS02580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005140"
                     /product="cobyric acid synthase"
                     /protein_id="WP_104977146.1"
                     /transl_table=11
                     /translation="MAALTVMVQGTASSVGKSLLCTALCRMFQRRGLRVAPFKSQNMAL
                     NSFATLDGGEIGRAQAVQAEAARVAPTVDMNPVLLKPEGDSRSQVVVLGKPIGSLHARD
                     YYASRGELKDIIAGALGRLRAAHDVVVIEGAGSPAEINLKDRDIVNMHVARVADAPVLL
                     AGDIDRGGVFAALVGTMALLDPDERARVAAFVINKFRGDLKLLEPGLEMLTARTGVPVL
                     GVVPYLKQLRIADEDSVSLEGRRRRAPAGAGQLDIAVVRLPRISNYDDLEPLEHERGVV
                     VRYIEGPGEIGGADLVVLPGTKSTMADLAWLRASGLAEVIAKRAREGGWTLGICGGCQM
                     LGGAIEDPEGVESAEPAARGLGLLDVWTRFERTKTVAQVRARLAGASFLGGAACAGGAD
                     GELAGYEIHMGRVERAGGARAAFEIRSRSGAAERALDGAVSADGAVVGTMIHGIFENDG
                     LRRSLLSALRERRGLPAAPAGEPAIPSRHDEYDRLATAVESSLDRALLDRIVGLDRRP"
     gene            complement(16556..17500)
                     /locus_tag="SOCE26_RS02585"
                     /old_locus_tag="SOCE26_005150"
     CDS             complement(16556..17500)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020465096.1"
                     /locus_tag="SOCE26_RS02585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005150"
                     /product="cobalamin biosynthesis protein"
                     /protein_id="WP_104977147.1"
                     /transl_table=11
                     /translation="MSAAAALLVAVALDLACGEPPAAVHPVVWMGSTIQLLKRRAPAGG
                     RIAELLWGALMALTVPCLFAALGAGLAALLAPHPALSVLLSGVLLKPTFALRALRGAAF
                     GVRDALAAGDLPAARAALGSLCSRDASDLDEPALVAASIESVAENTSDSVVAPLFYFAL
                     FGLPGALFYRAVNTLDAMVGYHGRYEYLGKASARLDDALNFVPARITALLLVTAGWLRG
                     ADARRGLAVLRRDGGLTESPNAGRPMAAMAGLLRVELEKRGHYRLGDPIAPLRRELIDE
                     ACRIMVLAALLFAALAALAALAIDVMGYWKEAL"
     misc_feature    complement(16559..16561)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17558..18133)
                     /gene="cobU"
                     /locus_tag="SOCE26_RS02590"
                     /old_locus_tag="SOCE26_005160"
     CDS             complement(17558..18133)
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020465097.1"
                     /locus_tag="SOCE26_RS02590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005160"
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="WP_104977148.1"
                     /transl_table=11
                     /translation="MSRDDGAAPRRVALIGGGVRSGKSAFALALARSLGQRRAFIATAQ
                     PFDDEMRARIAAHIRERGDEFTTVEEPVALPERIAALSGVDVVVVDCLTLWLSNLLLRD
                     EAEAHIHEHIEALAAAVESARPHVVLVSNEVGMGVVPESPLGRVFRDLAGRAHQRLGRS
                     ASELYMAMMGVILRLRPGPVAVVGEDGR"
     gene            complement(18130..19668)
                     /locus_tag="SOCE26_RS02595"
                     /old_locus_tag="SOCE26_005170"
     CDS             complement(18130..19668)
                     /GO_function="GO:0042242 - cobyrinic acid a,c-diamide
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020465098.1"
                     /locus_tag="SOCE26_RS02595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005170"
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="WP_104977149.1"
                     /transl_table=11
                     /translation="MSRQIPRLVVAGVASGVGKTTVTVAIARALRARGLRVALFKCGPD
                     YLDPTYHARAIAGASHNLDGWMMGRDAVLSTFAEESAGADVALLEGVMGLFDGASPAGE
                     EGSTAEIAKWLEAPVVLVADASGMARSIAALVQGFATFDPGLRVAGVVCNQVGSRGHLD
                     LLRQAQRSPPVLGGLPRDEAQRFPERHLGLRTADEAALPEERLDHWGARAEEWIGLDAL
                     LEIARGAPALPSPPPSPPPARAATVSGEPRVDPPGARPRAARIGVAFDEAFHFYYADNL
                     RRLEAAGAELVRFSPLRDVRLPDVDALYLGGGYPEVHAERLAENAAMRAEIRAFAGGGG
                     PIYAECGGLMVLAEAIRTLDGRAHPMVGLIPAEAVMCERLQALGYVEVETQARTILGQA
                     GLRFRGHQFRYSELRPVSPASPAASAPASPSTPAPSPPAPAASPAPAPATSSPPLPIEH
                     AYSVRRRRGGQVAREGYWTQSVLASYVHAHWASNPLVPEGLVASAAAYRKERAR"
     gene            complement(19668..20228)
                     /gene="cobO"
                     /locus_tag="SOCE26_RS02600"
                     /old_locus_tag="SOCE26_005180"
     CDS             complement(19668..20228)
                     /EC_number="2.5.1.17"
                     /GO_function="GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012232849.1"
                     /locus_tag="SOCE26_RS02600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005180"
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="WP_104977150.1"
                     /transl_table=11
                     /translation="MSAGAEAPGAAEAAEKRGLVIVYTGHGKGKTTAALGMVFRALGRG
                     MRVAVVQFIKGKWKTGERLFAETLPGLTFLVMGRGFTWESDDLSRDKAAARAAFDEAAA
                     LIAGGEHDIVVLDEITYAIHYGFIAEGELLSALRGRPAHVHVVITGRNAPDALVELADL
                     VTEMKSVKHPFAQGMKAQIGVDF"
     gene            complement(20225..21016)
                     /gene="cobM"
                     /locus_tag="SOCE26_RS02605"
                     /old_locus_tag="SOCE26_005190"
     CDS             complement(20225..21016)
                     /EC_number="2.1.1.133"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0046026 - precorrin-4
                     C11-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020465100.1"
                     /locus_tag="SOCE26_RS02605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005190"
                     /product="precorrin-4 C(11)-methyltransferase"
                     /protein_id="WP_104977151.1"
                     /sec_met_domain="TP_methylase (E-value: 2.6e-47, bitscore:
                     160.7, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVYIIGAGPGDPGLITVRGAELVARCPVVLYTGSLVPREVVASA
                     RPDARVIDSSGMTLDQIVAVFVEAKEAGHDVARVHTGDPVLFGSTAEQMRRLEALGIPY
                     EIIPGVSSFTAAAAALGRELTLPELSQTVILTRAEGRTPVPPAERLEELARHQATLCLF
                     LSITLLKDVAEALIPSYGADCPVAVVHKASCPDQKIVTGTLADIREKVRAEGIKSQSMI
                     LVGRVLTATDFADSRLYDPEFSHRFRKAEKRRASGPAEDGS"
     gene            complement(21030..21446)
                     /locus_tag="SOCE26_RS02610"
                     /old_locus_tag="SOCE26_005200"
     CDS             complement(21030..21446)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020465119.1"
                     /locus_tag="SOCE26_RS02610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005200"
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="WP_104977152.1"
                     /transl_table=11
                     /translation="MARVGRLGGALLAETQGTYYLIGNTKVPCDFQQAGFEPPGEIDAL
                     KKPYVQLLPLREVKVAAPVLLLDVEGEELARRLAQRFLIERNGSVSERLWRLVYSPDDP
                     LDDPEEPIERDARWLGDIPEAIWQLVRDNVLRCI"
     gene            complement(21448..22290)
                     /gene="cobJ"
                     /locus_tag="SOCE26_RS02615"
                     /old_locus_tag="SOCE26_005210"
     CDS             complement(21448..22290)
                     /EC_number="2.1.1.131"
                     /GO_function="GO:0030789 - precorrin-3B
                     C17-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020465120.1"
                     /locus_tag="SOCE26_RS02615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005210"
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="WP_104977153.1"
                     /sec_met_domain="TP_methylase (E-value: 1e-30, bitscore:
                     106.5, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEHGVLSIVGIGPGAEEHASRAALEAIAASDLIVGYTTYIRLVK
                     HLIQGKEVIKTGMTEEIGRARAAVERARDGARVAIISSGDAGVYGMAGLVFQVLQEIGW
                     KRGGSPELRIVPGMTALNACASLVGAPLGHDFCAISLSDLLTPWPVIERRLEAAAAADF
                     VIGLYNPASGRRTRQIVRAQEIIAQHRAGTTPVALVKSAYRKLESAVLTDLDHFLEYEI
                     GMLTTVLVGSTNTFMFEGYMVTPRGYTNKYTWDGAALPGQTPGRSLVLSDEGAAAEEV"
     gene            complement(22283..23422)
                     /locus_tag="SOCE26_RS02620"
                     /old_locus_tag="SOCE26_005220"
     CDS             complement(22283..23422)
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012232870.1"
                     /locus_tag="SOCE26_RS02620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SOCE26_005220"
                     /product="cobalamin biosynthesis protein"
                     /protein_id="WP_104977154.1"
                     /transl_table=11
                     /translation="MTAARKPYAVYAITRHGIAIGRTLLEGLPGADLYVSQKLFDAAPA
                     GAKPLPLPMGPLLTEAFTAYDCHVFVISVGAVVRMIAPLLKNKKVDPAVVCVDDTARFS
                     ICVLSGHVGRGNAFTEKVAALLGALPVVTTASDALGTLTVDILGRELGWTLDDPDRNVT
                     RGCAAVVNAAPVLFVQEAGEPSFWPEATPLPPGVRYATSLDGVDPDAWEILLVASDRDL
                     ARSHPAVVERAVVYRPKSLVLGVGCDRGAPLDMVERGVDKLLAEHGLSAKSVKALATID
                     KKADEEALLALSERRGWPLVTFTAEELDATEGIENPSETVKKHVGARGVAEPAALRAAG
                     AARLLVPKRAYTEEGAGRSMTLAVARVPFPKRTVEESHG"
ORIGIN
        1 agccgagcgc gagccgatgg agcggggagg gggcgcgcag acgcgcgagg aacgcagggg
       61 atcgcatgga agtacctcca aacgagccgc cttcgcgcgg cccgcacggg actgtagcac
      121 cgggtcggta atgtctgaac aaacattata caaagattga atatgaatgc acccccgcgg
      181 ctggtggcct cggcgcagga cccgcgccgc cggcggaggc ctgggccggc ggcgcaggca
      241 agaggtgatg gcgcggcgcg ctggcggagg tctgggccgg cggcgtcggc ggggcgcgcc
      301 ggccggagct cacgcgaggc aggcgcgctg cggcgccgcg gcggcggcga ggcccgggac
      361 gagcgtgtgg aggcgcgccc gctgccggct ggtcagctcc ccgagcgcgc ggaggatcgc
      421 gaggtccttc tgcttcgctt ccacgatcac caccacctcg cggcggtccg aggcctcgtc
      481 cacctcctcg cagaagcgga gcaggccgcg gccggtgatg tgctgcgcgt gggcgccgga
      541 cggcttgcct ttccactgct cgctgtagtg gagctcgggc agctgctctg ccggccaggt
      601 gcggagggcg ccctcgagct ccacctcgta aggcgcgctc ctcgggttcg ccgcccagtg
      661 caggttgtcg aacacgatgg gcacctcgcc cccggtggcc tcgagcagct ccggcacggt
      721 ccagcaacgc tcgtcgttct ccagcgcgag ccggtgccga gcggccggcg tgagccgcgc
      781 gatgccctcc cgcagccggg cggcggtgct ctcccggtcg ccgtagacgc cgcctccgtg
      841 cagcgtgatc gacccctgcg cgccgagcag gtccatgacc cagccctggt cgtccatgac
      901 cgcgagcgag ttctgcagca cctcctcgcg cggcgacgag agcaccacga actggctcgg
      961 atgattcgac aggtgcacgt cgccgtgcgc cgcggcgcgg cgcacggcgc gcaggtccgg
     1021 caccagcatg cgcgcccccg gcgcgatatc gagcagcggg aagagatcgc tggagatccg
     1081 gtgggccgtc aggccgagcg cggccgaatg agcgatggat cgccggacgt actccgcgtt
     1141 gtacgtgtag atgggcgtga gctcgaccag gcctttgagg tagcgcccga gctgagcggt
     1201 cctgagcgag ggctccggca tgcccagcga ctgacagaca tagccgagtc ggatcatgcc
     1261 accagcgtgt gtcgtccggg gtctgtcggc atcgggcttg caacgattta gcccatgcca
     1321 tcttccgaac agtccagcct ggcccgtcag accgcgcgag atctcctgtg ccgcgccggg
     1381 gcgcagaggt cccgtgtggc gatcgtgtac cacgccgatg cggacgggac gtcgtccgcc
     1441 gcgctcgcct gctttgccgc ccgcgccctc ggcgccgagg tggtgccgga gacgcccgac
     1501 aagggcgaga acgtgcacag cccggcgttc ggcgcgcgcg tgcgggcgac gggcgccgcg
     1561 ctcgcggtgg tgctcgacac gggatcgagg ccggggcggt tgttcgaggt gccgacggtg
     1621 atcgtggatc atcaccgggc ggacccggcc gaggcgcccg aggtggaggc gttcgtgagc
     1681 acgttcgggg acgatcgcgg gacctccacg agcgcgctca ccttcgagct gctcgcgccg
     1741 atcgcgccga tcgcgccgcg cgcctggctc gcggcgctgg gcctgctcgg cgatctcggc
     1801 gacgtcgcgc gccgccaccc gctcgtcgcg gccgcggcgc ggcagcacgg gttcacggcg
     1861 ctgcgcgagg ccgtgtcgct ggtgaacgcc gccggccgct ccgcggccca cgacgcgggc
     1921 gtcgcgctcg cggcgctgct cgaggccgag cgcccggcgg acctcgcgcg cggcgacggc
     1981 gaggcggcgc ggcggctgcg cgcgctccgg gaggacgtgg cggccgcgac ccggcgcgcg
     2041 atccgcgccg cgccgcgcgt ctacggccgc tgggcggtca tcgagctgga cgagccgtac
     2101 cggatccatg gccccgtcgc gagcgcgtgg acgcggcgga tggagggccg gatcgtgctc
     2161 gtcgcgaacc ggggttacgt gccggggcgc gtgcacttct cggtgcgatc gcacgagccg
     2221 atcgatctcc gggcggcgct gtcggcgctg ctgcccgacg cgggccccga cgtcgcggcc
     2281 gggcacgacc gggccaccgg cgggatcgtc gaggtgccgg tgttcgaaga gctgctccgg
     2341 cgcatccagg gcgaggcggc gcagggcgcc gcggcgtgag cgagcgcgcg gcgtgagcgg
     2401 ggcgcctgcg cagcgatcgg cgctgcacaa cagcacgcgc ccgcgcatgt caagaggcga
     2461 gcacgccctg gcctaccgag ctcatgcctg caaggcagct tagtttcgcc caggacgatc
     2521 ttaaacccac ctcctattgg cgagcgcgcc gccgtgcggg cgcgggtgga gggcaacgtc
     2581 ccgtcgagag acggccaatc ccgcggggga tccgccggcc gaagaccgcg ctggcgcggt
     2641 gcggcccaca acacctcgcg cgcgagcgag gcgataacca gagccgaatc gccgagcggc
     2701 ggccgtcgcc atacggcccg catcacgcgg cgccggctgc gtcatcttgc gccatctcgt
     2761 gtgtacctgg atgggggcaa gggtaggcgc cggtcggtgg ttttccgctg gaccgcacca
     2821 tgaaaaccgg tgtgtctccg cggcgcgcga cgcgcgtggt atgggggaac ccagcgaggt
     2881 gcagcgagat cttctaccat tgctggtgca tgtgatagga tccctgacca tccggcgctt
     2941 ctgaagagcc gagagaccgc gcgaccgtcg accgtcatct gcgcaacaaa gctcgaccgg
     3001 ctggggggcc tatccaggta aggcgtcttc cacccctcac gaagtcgggg cgtcgcgggt
     3061 cttccgcctc caggcgtcct tttcgtgcgg atgaaccggt tttttgaggc acacacaaat
     3121 tcctgagggt gatgtaacgt gattgggcct gcgcagcttg agctcctcgg ggcgaatcgc
     3181 gacggagccg gccgcaggtc ctgcccgggt ctgggcaaga aggggttagt actcacgagc
     3241 cgcatggcac acgcagagct gacgctttcc tgtgccgcca gacgagcaac cgatcgctga
     3301 agcgcggagc ttcgcgcggg ccatggttgc actgccggcg caccgaaggg ttgtaggggg
     3361 taagtgaaat ggtcgagctc gtcaatcacg aactggtcga cacgctgcac gacggatctc
     3421 ggagcagcgt ctacctcggg cgaagcaaga gcaccgggaa gctctgcgtc atcaaggtgg
     3481 cccggaaggg cgcgaacggc acccgcaaca tcgcgatcct gaagcgccag tacgagatca
     3541 cgcggcggct cgagctcgac gggatcgtca aggtccacga cctcgaggtc cggctcgact
     3601 acgcggcgct catcatggag tacttcgcgg gccggtcgct ccgggcggtc atcgacgacg
     3661 gcgggaacgg cgtcgggctc gtgccggcga cgaggatcgc gctgcagctc gcggcgaccc
     3721 tcggcgcgat ccacgagcgg aacgtcatcc acaaggacat caagccgagc aacatcatcg
     3781 tcgacgacgc gatcagcacg tcgaagatca cggacttctc gatcgcgtcg ctcctgccgg
     3841 gcgagcaggc gacggtctac gacccgtgga cggccggcga gggcacgctg cagtacatct
     3901 cccccgagca gacgggccgg atgaaccggt cggtcgactt ccgctccgat tactactcgc
     3961 tcggggtcac gctctacgag ctcacgacga ggcacctccc cttcgaggcg accgacccga
     4021 tggagctcgt gcacttccac atcgcgaaga ccccggtgcc cccgcatcag gtccggcaat
     4081 cgatcccgga ggcgctgtcg aaggtcatca tgaagctcct cgcgaagacg gcggaggagc
     4141 gctaccagag cgccttcggc ctgaaggcgg acctcgagac ctgcctcaag atcatccaga
     4201 ccggcgagcc gtcgtcggat ttcgtgcccg gccggcagga caggccgacc cggctccaga
     4261 tctcgcagcg gctctacggc cgggaggacg aggtcgacac gctgatggag gcgttcagga
     4321 gcgtcagcga gcccggggcg gggggcgcga ggtccggcca gtcggaactc gtgctcgtgg
     4381 ccggctactc gggcatcggc aagtcggcga tcgtgaacga gatccacaag ccgatcgcga
     4441 ggcaaggcgg gtacttcgcc gccggcaagt tcgaccagtt cacgcgcaac atcccgtacg
     4501 cgtccatcat cgccgcgctc cgggagatcg tccggcagat cctcacggag agcaaggaag
     4561 agctcgccga ctggaaggcg aggatcctcg cgtcggtctc gccgaacggc caggtgatcg
     4621 ccgaggtgat cccggagatc gagctcatca tcgggaagca gccgcctgtc ccctccctgg
     4681 gccccatcga gacgaggaac cggttcaacc tgacgttccg gagcttcatc ggcgccatca
     4741 cgctgaagac gcgggcgctc gtgctgttcc tcgacgacct ccagtgggcc gacacgggct
     4801 ctctgaacct catcagcgtc ctcatggagg accccgacat tcgccacttt ctgctgatcg
     4861 gggcgtaccg ggacaacgag gtcgacgacg ctcatccgct catgatgatg ctgagctcgc
     4921 tcggtaaggc caagacgcgc gtgcgaacgg tcgcgctgaa gcctctcgcc cacgagcacg
     4981 tcaatcagct cgtgtcagat agcctgggga ccggtcaaga agaatgtcac ctcctctcgg
     5041 agctgatcca cacgaagacc gacggtaatc cgttctttgc cgtccagtat ctgacgaacg
     5101 tctaccgcga ggggcacctg agcttcaact cggagcacgg tgcgtggcag tggaacgcca
     5161 gcggcatcgc gaagatgacg gccacggaga acgtggtcga tttcatggta cgcacgatac
     5221 gcagcctggg cgagacgacg cagcgggtcc tgaagtacgc cgcatgcatc ggcagtcagt
     5281 tcgagctgaa gctgctcgcg cagctcaacg ggacagatct ccgcagcacc gaagagtatc
     5341 tttgggctgc gctggaggtc gggctcatcg tcccagtcga tggcgactat agaatcgtac
     5401 ggttcctcga cgatgccgag gagagctgcg ctgtctacaa gttctcccat gaccgggtgc
     5461 aacaggcggc atatcggcta ctcgccgaag gcgagcagca aagagctcac ctgatgatcg
     5521 ggcagttgat gctgcagcac acgccgcctg aatccatcga agagcggatt tttgatatcg
     5581 tgtcgcacct caatctcggt gctccgctcg tggtcgatgt ggatagtcgc taccgagccg
     5641 cggcgctcaa cgtaaaggct gggcagaagg ccaggcgctc caccgcgtac ggtcccggag
     5701 tgcagtgtct ccgggcggcc gcggcgtttc tccccgagga ttcctggcaa acgaactacg
     5761 agctgtcgct ctgcgtatat acagatctta ccgagctcga gtacttgacg atcaatttcg
     5821 agcgcgccga ggaggccgcc agagtcgtcg taaaccaggc caaggatcca ctggagaaga
     5881 tccgggtcta cgagacccag atccagttct acatttcaca gaaccgcatg ctagacgcca
     5941 tcgacgtggg catgagcgtg ctcagcacgc tcggcgtcac gctctccgag gcgcccccga
     6001 aagatttcga catcccccag ctggagcagc ttccgccgat gacagacaag cggatgcagg
     6061 cggccattca aatactgtgt actgtccagc cggccatcta cgttgcgaag ccaatgctgc
     6121 ttctgtctaa cgcgttcaca atggtggata tctgtacgaa gtacggaaat tcgcctactg
     6181 gcgcgttcgc ttacgcgatc tacggaagta ttcaatgtaa tttcatgggt aacgttgatg
     6241 tgggctttgc gctcggtcgg ttggcgatcg atctggtcca tcggtttggc gccgtcgacc
     6301 tggaatgcaa gctgtataac gccgtgtacg tcttgatcta ccactggaag cggcccctca
     6361 aagagacggt cgagccgctg ggccgggctg ttcaggccgg cgtggaaatc ggtgacatcg
     6421 agtacgccgc gcatagctcg tttgggtatt cgataaactc cttctttgcg gggatagatc
     6481 tggcgacggt cgagctgcgg atgaagcaag cggtcgacct gtcgcagaag tttgatcagc
     6541 agtttccgct ctaccacatc aagatctgga aacagcttgt gagtggcctg agagacgtgt
     6601 acgcggagag gctgaggctc gtcggggaga gcttcgacga gacaacgatg gtcccatacc
     6661 tgggcaggcc atcgatgttc tcacttcatc tcgcaaaggg tatgctgctg tactacttcg
     6721 gcgagtcgaa gcatgcccgc gattgccttc gctcctgcga ggagtaccag gacggggccg
     6781 cgggcgtggt caccatcgtc gagcagaact tctactattc gctctcgatc ctcgcttccc
     6841 ttgaccggct cccgaaggag gagcaagaga ttgagctcac gaaggtcgag gagaaccagc
     6901 gcaggctcga ggcgtgggcg cgcgccgcgc cggataacaa ccagcataag cacgacttgg
     6961 tgggcgcgga gctggcgcgc tccagaggcg ccccgatcga cgcgatggag ctctacgata
     7021 aagctatcga gggagcccga aggtgcggat tcatccagga ggaggccctg gcgtgcgagc
     7081 tggcgtcctc gttctatcga aagctaggtc gccaagagat cgcccaccac tacatgatcc
     7141 tcgcgtatag aggttatgcg ttgtggggtg ctgatgcgaa gtgccagagc ctcgtcgcgg
     7201 cgttccctca gctcatgttt gagggggcgc ctgacaggac cgcgtcgatg acagggacgt
     7261 ccagccacga cggcgcagcg ctggacctct tgagcgtcat caaggcgtcg caggcagtcg
     7321 cgagcgagat cgtgctcgag aggttgctgg aaaacctgat gacgatcgtc atcgagaacg
     7381 tcggggcgca ggccggggtg ctcgcgcttg tgcgcggaga tgcgctgttc gtcgaggccg
     7441 agcggacggt ggagccgaag caagtcaatg tgctgaaatc tgctccgata tcttcttgca
     7501 agaaggtccc gctgtccgtg gtgagctacg tgcagcgtac gctgcaaacc gtcttgctgg
     7561 acaacgcggc tgcagagcca cgattctctg aggatccgta catacgggcg aggcagacga
     7621 agtccttgat gtgctcgccg atcctgcgcc agggccgcct ggtcggtgtg ttctatttcg
     7681 agaacgacct gtcgacagga gtcttcacca agagtcggtc tgagctcttg agccttctct
     7741 cgacgcaggt ggcgatctcc atcgaaaacg cgaagctgta cgaaggcctc gagcaggcgg
     7801 tcgccgagcg cacggaagag ctccgtgtgt cgaatgagcg gctccaggcc gtgaacgagc
     7861 ggctgcaggt ggagctggcg gagcgcgagc gcctccagga agagcgagtt cagatgcagg
     7921 aggagatcat ccagacgcag cgggctcggc tccacgagct gtcgacgccg ttcatcccca
     7981 tcaccgacga catcatggtg atgccgatca tcgggaccat cgatgacaag cgggcggcgc
     8041 agatgctcga gacggcgatg gaaggcgtcg cgacgagctc tgcgagggtc gtgatcatcg
     8101 acatcaccgg cgtgaagacc gtggatacca gcgtggcgag caggctgatg agcctggcca
     8161 aggcggtgaa attgctcggg agcaaggcga tcctcaccgg gctccggcct gcggtggcgc
     8221 agagcctcgt cgcgcttggc ctcgacctcg gatcgatcga gacgaggtca aacctcaagg
     8281 caggcatcgc gtacgcgatg aagcggaccg cgacgattca tcgccacgcc tgaagcggtc
     8341 atcgggagcg agaccggcga gcgggtcagg cgcgctcgaa cctcacgcgt gcggtggtcc
     8401 ggggttgcgt cagcggcagg taaccagggc gtggctccgc tccgtcgtgc acaggcctta
     8461 gccctctcct cttgcacgcg cgtgccagcg cgatctgcaa gcagaccccc tcaaagagcg
     8521 cgagcccgta accaaggcaa aaatgcgagc caccgccgaa gggcgcgagc tcgaggggcg
     8581 tgggcgctcg cgagcgccct gtccagcgtc cggcatcgaa acgttccgga tggggaaagt
     8641 ttgtcttgtc gaggccgagc acggcggggc tgatggccat cggtgtgcct gccttgatgc
     8701 tgcgccccga caccacgatg tcggtgcccg tcctgagaag cataaaccac accggtgggt
     8761 acagcctcag agcctcccgg aagatggcct cggcgatggg gaatttgctg atgtccttcg
     8821 gagacgaagg caaggggcca cctgcctggg cgtcgtgctc gtccatcaac gaacgccaga
     8881 ggtcagggcg ccgagcgagc aggagaatca cccatgcaag gacggaggcc gaggtctcat
     8941 gccccgcgaa gaggatcacg cgcaggttgt gcaccagctc gtcggtcgag agcgcctcgc
     9001 cgttctcgtc acgggcagac gtcagcgtac ccaggagacc accctgcgca tgaccgagac
     9061 gcgcgttgtc gacgagctgc ctcagctcgg cgttgagcca cgtctgagcc cgggccgagc
     9121 gatagcgcgg caggcccggc aggtgccccg gcaccggtat gagcccgagg atgaaatcgc
     9181 gatacgcttg cttccatgcg tggaggcgat ccacggggac gcccgcgagc cgaagcacga
     9241 tctcgagcgt caggtcttgc atctctggca gcgcgtcgac ggagccacgc gacagccatc
     9301 gctcgatgtg ctcctcgatc agcgatacca gcggcgccat caggcccgac accgacaggc
     9361 catgcgtgga gaacgacggg cccaatgccg agcgcatatg ccggtgcgat gcgccatccg
     9421 cggtgaccag cgagccacca aacatggatt tgatttctgg gtctgaggcg tcgttttcta
     9481 cagaaggcgt gcgcaggaga tcgaggctgt caggcccgac gcagaagagg cgctcgcggc
     9541 cgaagccaag gtcgacccag aagacggggc cgagctccgc ctggctgcga aggaggaacc
     9601 ccggcgcgtc gaggtggagc cgaggtagat gaccggctat cgggagcccc ccaggagcga
     9661 ccgggtggtc gtcacgatcc gcgcaaggac ggaccttccg ccagagcctc accggccagg
     9721 atccgcgcga cccaccgccg agcgagtttt tgctgtcgga aggagagccg ccgtgtgctg
     9781 gggtcgatac gtcttcgtgg atggggctga ggatgcgtgc ttgttgcatg gctacggatc
     9841 ttctgttctt acttgctcgc tgcgctggcg tcgccgtcgg cgtggtgacg ttccgtggcc
     9901 gttgtccagt tgaagatgtg tggggcgccg gctgactcag ttgggcacgt catggctata
     9961 agtgggattg gcggtccagc gcgtgcggag actatgttgg ttacggtgcg gtggtgattt
    10021 gtttaagctc gacgaagtcg ccgatcgagt acatcatgtc tgctgcggcg agctggtgga
    10081 gcatacagat gctgaggctt gaagtcgggt cgtccgcgct tctgctgcct atgttttgct
    10141 ggcagaggtg ctcgacctct cgtgcgaatt cgtcgatcat tctgcgaaga tctgcgcgag
    10201 ctcggcccgg ggggacgccg ttgctcatca tgatcgatac ggggttgggt ttcctttcga
    10261 gtacgtcctt ctcgtaggtg gcgacatcgt tcatcaggcg tagcgctccc gacaagggtg
    10321 cggtaacggg ctcgatgacg cgccagcgct ctccggcgcc ggggagcatc gcgttcaacg
    10381 cgctcatgca tagagttacg cagatcgtga cgctcgcggt tcgtagatac tccgatacgt
    10441 cggtaggtgc gctctgttca atgcgccagc gtgcctcggt gcacatcgcc gggaccacgc
    10501 cgtcgatgag gcaccggtcg aaagtcctga ggcccacggc gtcaggggat gcctcctcga
    10561 gcgaccgacg gagaggttgg atcccgtcga cgatgtccat gatcgagtag tccaggccgg
    10621 gcgcgtcttg agtcgggtcg cgcgcgaggt ccatgtccag ccacgtcagc tgcacgtcgc
    10681 tcggcagctc cagccggcgc cggagcaacg acgacaggtc gtctgcataa tcgatcgacg
    10741 ggcacgtatc cagcagggcg tccatcgcgt acacccagcc gctcatgtag gaagggatgc
    10801 gcgagagctt gctgcgaagc tgtggtggcg tggtcaacgt cgcaaatgaa gccgcggccg
    10861 ggagtcgctc cgacacggtt gacccgaata ccgagagctc ggcacgcaac gtggcggtga
    10921 gcccccggat gaactcccct gtaccaggag cctgcagctg ctcccgaatc agtcgcttcg
    10981 cctcttcagc cttcatctcg ccccctcacc gcctgccccc gcgggggccc ctcttccgcg
    11041 cgctccctcc accggcggcc agctcgcggg gcagcggatc gggcgtgccc aggaagcgca
    11101 cctcgctcac gcgcctccgg gacgcgccct gcagcgccgc gtcgatcgcc gcgttcacga
    11161 tgttgcgcgg cgtgtacagg cacttctcga tccagagcgg cgggtgctcc gcgccttgct
    11221 gcgacaggag gtagtcgacc gccagctcga gccgccagtc gtctccaggg agcgccagcc
    11281 ggcgcgcgtg ccggagcgcc aggacgccgt acgccgtctc ctcggccgtc gggcggtcgt
    11341 agaaccccca ggagccgtcc gcgttctgcg tctgcctcac ccagtcgagc gccgtgcgcg
    11401 caagctcgtc ggccacatgg ctgtggggct ccgggaggtc ggcgagcgcc gcgagcgcgt
    11461 gggcggtcgc gtagtacggc gagatgtgcc acttgtcgat ccagtacgtc ccgtgggtcc
    11521 gcgtgtcggc caggaaggtg aggatccggc cgatcttcat gtccctctcc tgggtggacg
    11581 gcatccactt gagcgtgtcg agcacgtgca tgttgacccc cgaggacgcg tgccgctcgt
    11641 aagggtagct cgcatagtgc ccgtcgcgtt cgaagggcga cagcgcgtcc ggcttcacgt
    11701 cgtaccccat ggagcggagc agcagcatcg cgaccgccgt gtcgtccgcg tccggcaggg
    11761 ggaaggtcgc agacgcgctg atcccctctc cggcgtcgag ggccgcccgg agcgccgaga
    11821 tcgtcgcctc gggcagcaag ccggggccgc gcgccccacc gaggaagtga tggtacgcgc
    11881 tccagagcag atcgtacgtc tcgcaggggt gcacgacggg caccgccgcg ccgccgtcca
    11941 gctcgaggca ccgccgcagg tagtcgaccg cggcctcgct ctccctcttg tgaaggaaga
    12001 acgccgtggc cgcaggagag ctgccgaccg acccgttctc ccactggacg gaagccaggc
    12061 ggtccacatc gacctcgtcg cccaggaact cgagcgagtg gacgatcgtg accttgggtg
    12121 agtagaggag atcgctcggg atcatcgcga gcttgcgccg gcgctgctcc gcgtagatgt
    12181 cgaggtacga cggcagccgg acgccggcgc gggccgccct gctctgcaac gtcggcagga
    12241 gcagctcgaa cccgacgagc tcgacgggct cccgcgagag cgcgtgtgcg tgctgccaga
    12301 tgtagcgctg cccgctctcc accgcgcgtg tcgtccgggc gtcgcccttg aagcgcgtga
    12361 tcgcgcagag ggcgctcagc gtcgacagga tgcgatcatg ctcgtacgcg atctcgccgc
    12421 cccagctccc gtccggccgc tgatgctcga acacccactc cagcgccgcc gggaacctcg
    12481 gccgctccgg gcgatccggg tcgggcaggc tcgcgaccca cgccgtgtcg taggcgcagc
    12541 tggcgatgga cgggtgtgca gctggatcgg gattggtcgt gccctcgtac gtcatgttct
    12601 catcctttca gaaccaaaaa accggtgtcg cgcggatctc tgctgcggcg cggcggctgc
    12661 tccgcgcgtg gacagccgcc ggggcctgat gggcgcccgc ccgcgcttca gctcgccgaa
    12721 aggtcggccg cgagcgcgtg cgcgatgggg gccaggcagc gccaacccca attaggaagg
    12781 acctttgcca tccagtggat ctcgagctgc tgcgcggcgg acctgatcca acccgcggtc
    12841 gcgcgcagcg ccccgcagcg ggcgagggcg tccaccgcct cgtccaccat cgcgagggtg
    12901 cgctgctccc gcgcgcactc gagcagggcg cggacgggcg cgacggcctg cgcgctcccg
    12961 tgctcgagcg cccagatcac ggggaacgac agcttcccct ccatcagatc acggccgcgg
    13021 tgcgtgcgcc ccttgtcgcc gacgatgtcc aggtaatcgt cctgcacctg gaacagcagc
    13081 cccacgtcct ccccgtaggt cgtggcgctc tcgacgacgt cggcctccgc gcccgccgcc
    13141 agcgcgcccg cgcggacgca ggcggcgaac agcgcccccg tcttgctcct ggccatggcc
    13201 tcccacgcct tcagcgtcac cgccggcgcc gggcgctggt ggagatccag atccatcgcc
    13261 tgtccctcgg cgatccgcgt cagcgcgtcc atgagaaacg gaaggaactg acgtgctgcc
    13321 ggggagcgcg cgatgcgctc gatcccctgg aagatgaggg catcgccggc gttgatggcc
    13381 tgcgcgacgc cccactggaa ccacacggcc ggacggcctc tacggtgcga gtctccatcc
    13441 tggatgtcgt catggatgag cgtcgcgttg tgcaagagct cgaggccgac cccgagatcc
    13501 agcgcatcct cggcgcgtcc gccgaggttg atgcacaccc agatgggcaa cagggcgcgc
    13561 atccgcttgc cgcccgacgc gaggtgatac gccgtcatcc cgtggaccag ccccgcgccc
    13621 tggcgctcca tgacgcgccg ctcgacctca cctgagtacc gccgcctcac ctcttcgtaa
    13681 tcgaggagcg cggtccgcag ggcgcttaag ccttctatac tcgtcgtcat cattggttcc
    13741 cgcgaccccc cgtgttgccc aaggtcaaat gtcctgtctc caggatcaca ggaaacgtgt
    13801 gtcgatcgct ggggggacac ggctcttgcg cgatagagtg tctcgcgcga tggatgacga
    13861 ttgctcgttg agcggcctgc gtccgattgc gatcgaaatt accgattatg taaaccctgt
    13921 caagctgatt tcgcgatgtt gcgcacagag cgatagaggc gcacgcgtca cgtcttctat
    13981 cgagcagctc gcatcatgca gaactatcgg aaccacgcac ggctcgcgac atccgtgcag
    14041 gatcgttcac gtcgccgtta ccggaacgtg ccagccgcgt cccttcccgc ccgtgcgcgg
    14101 cgtcacccgt gacgctcgct cgacctcgga cgcggcctgc gcggcgcggc ctcgtccacc
    14161 atgcagccag ccggcgcgcc cggacggccg cgcgctccat gtcccggaca cgaagcgccg
    14221 ccgcgccgat gcacccgtgt gcagcgccgc gcacgtgtcg acacctcgat cgagcctgcc
    14281 tcgcgcatcc gtccgcttcc ctgagatcaa cattccaagc catggagcac gtcgatgcgc
    14341 gactccggag agtcgcacat cgcacgacat gtcacgtccg tatcatagcg gcgaggtcac
    14401 cgcgggcaag ttaatccttc gtaagagggt tgaacgcccg gatctcttgc gatttcatgg
    14461 acttgtgcgt gtcgggtttc agccgtgaaa cgacgtaatg aaacggcgtt gcaccgatgt
    14521 gctctgcgat gccgcgtcga gctcggcctg ccgaaccaat gagcatggca ccaggccgtc
    14581 cgtagcgccg cgttttttct tagtacggca aacatctcga gtctcgccgc gcgcggcgag
    14641 agcggcgaga gcggcggatc gcgctgcgcg ctgcgcgctg cggcgcggtc gctcctgtcc
    14701 ggagcggcgt cccgtcgcgg agcgctctgc gagtgttcga ttcctgcaac acggaaacag
    14761 caaagaaacg cgcgcgctgg cgtgcgacga cagcagtgaa atccaatgga attgctgtcg
    14821 atatcgacat gaacacgaca gcagcatgac gcgcgtgttc accgggcgcg gcgcgtaccg
    14881 cagcgcgttg gcgcgcggtc gtcgtcctgt aacagccgct ctcgcctcgt ggtcgcgtgg
    14941 gcgagggggg tcgggggctc cgccgccggc gcggctcagg ggcgccggtc gagccccacg
    15001 agggctcagg ggcgccggtc gagccccacg atccggtcga gcaacgcgcg atcgaggctc
    15061 gactccaccg ccgtggcgag ccggtcgtac tcgtcgtgcc ggctcgggat cgccggctcg
    15121 cccgcgggcg cggcgggcag ccctcgccgc tcgcgcaggg ccgagagcag cgaccgccgg
    15181 agcccgtcgt tctcgaagat cccgtggatc atcgtcccga cgacggcccc gtccgcggag
    15241 acggccccgt cgagcgcccg ctccgccgcg ccgctccgcg accggatctc gaacgccgcg
    15301 cgcgcgcccc ccgcgcgctc cacccggccc atgtggatct cgtagccggc gagctctccg
    15361 tccgccccgc cggcgcacgc cgcgccgccc aggaacgacg cgccggcgag ccgcgcccgc
    15421 acctgcgcca ccgtcttcgt ccgctcgaac ctcgtccaca cgtcgagcag cccgagcccc
    15481 cgcgcggccg gctccgccga ctcgacgcct tccggatcct cgatcgcccc gccgagcatc
    15541 tggcacccgc cgcagatccc gagcgtccac ccgccctccc gggcgcgctt cgcgatcacc
    15601 tccgcgaggc cgctcgcgcg cagccacgcg agatcggcca tcgtgctctt cgtcccgggg
    15661 agcaccacga ggtcggcgcc gccgatctcg cccggaccct cgatgtaccg gaccacgacg
    15721 ccccgctcgt gctccagcgg ctcgaggtcg tcgtaattcg atatgcgcgg caggcgcacc
    15781 accgcgatgt cgagctgccc ggcgcccgcg ggggccctcc gccgccggcc ctccagcgac
    15841 accgagtcct cgtccgcgat gcggagctgc ttcagatagg gaaccacgcc gagcaccggg
    15901 acgcccgtcc gcgcggtgag catctcgagc cccggctcga gcagcttgag atccccgcgg
    15961 aacttgttga tcacgaacgc ggccacgcgc gcgcgctcgt cgggatccaa gagcgccatc
    16021 gtcccgacca gcgccgcgaa cacacccccg cgatcgatgt cgcccgcgag cagcaccggc
    16081 gcgtcggcga cgcgcgcgac gtgcatgttc acgatgtcgc ggtccttcag gttgatctcc
    16141 gcggggctgc ccgccccctc gatcaccacc acgtcgtgcg ccgcgcgcag ccgcccgagc
    16201 gcgccggcga tgatgtcctt gagctcgccg cgagaggcat aataatcgcg cgcgtgcagg
    16261 ctcccgatcg gcttgccgag gacgaccacc tgcgagcgcg agtcgccctc cggcttgagc
    16321 aggaccgggt tcatatcgac cgtcggcgcg acgcgcgccg cctcggcctg caccgcctgc
    16381 gcccggccga tctcgccgcc gtccagggtc gcgaaggagt tcagcgccat gttctgcgac
    16441 ttgaacggcg cgaccctgag gccccgccgc tggaacatcc ggcagagcgc ggtgcagagc
    16501 aggctcttgc cgacagagga cgcggtgccc tgcaccatga cggtgagcgc tgccattata
    16561 aagcctcctt ccaatacccc atcacgtcga tcgcgagcgc cgcgagcgcc gcgagcgcgg
    16621 cgaagagcag cgccgcgagc accatgatgc gacaggcctc gtcgatgagc tcccgccgga
    16681 gcggcgcgat cgggtcgccg aggcggtaat ggccgcgctt ctcgagctcg acccggagca
    16741 gcccggccat cgccgccatg ggccggccgg cgttcgggct ctcggtgagg ccgccgtcgc
    16801 gccggagcac ggcgaggccg cggcgcgcgt cggcgccgcg gagccacccg gcggtgacga
    16861 gcaggagcgc ggtgatcctc gcgggcacga agttgagcgc gtcgtcgagc cgcgccgacg
    16921 ccttgccgag gtactcgtag cggccgtgat accccaccat cgcgtcgagg gtgttcacgg
    16981 cgcggtagaa gagcgcgccg gggaggccga agagggcgaa atagaagagc ggggcgacga
    17041 cgctgtccga ggtgttctcg gcgaccgact cgatggatgc ggcgacgagc gctggctcgt
    17101 cgaggtcgga ggcgtcacgg ctgcacaggc tcccgagggc ggcgcgggcc gcggggaggt
    17161 cgccggccgc gagcgcgtcg cgcacgccga aggccgcgcc gcgcagggcg cgcagggcga
    17221 aggtgggttt gagaaggact cctgacaaaa gcaccgagag ggccgggtgc ggggcgagca
    17281 gcgcggcgag gccggcgccg agcgccgcga acaggcaggg gacggtgagg gccatgaggg
    17341 cgccccagag gagctccgcg atgcggccgc ccgccggggc acggcgcttg aggagctgga
    17401 tggtggagcc catccacacg accgggtgga cggcggcagg cggctcgccg caggcgaggt
    17461 cgagcgcgac cgcgacgagc agcgcggcgg cggcgctcaa cggccgtcct caccgacggc
    17521 agcggcgctc atctttcctc accgacgacg gcggcgctca acggccgtcc tcacccacga
    17581 cggcgaccgg gcccgggcgc aggcggagga tcacgcccat catcgccatg tagagctcgc
    17641 tcgccgagcg gccgagccgc tggtgcgcgc gcccagcgag gtcgcggaac acacggccga
    17701 gcgggctctc ggggacgacg cccatcccca cctcgttcga gacgagcacc acgtgtggtc
    17761 gcgccgactc gaccgcggcc gcgagcgcct cgatgtgctc gtggatgtgg gcctcggcct
    17821 cgtcgcgcag cagcaggttc gacagccaga gcgtgaggca gtcgaccacg acgacgtcga
    17881 cgccggagag cgcggcgatg cgctccggca gcgcgaccgg ctcctccacg gtggtgaact
    17941 cgtcgcctcg ctcgcggatg tgggccgcga tgcgcgccct catctcgtcg tcgaacggct
    18001 gggcggtcgc gatgaaggcg cggcgctggc cgagcgagcg cgcgagcgcg agcgcgaagg
    18061 cgctcttgcc ggagcgcacg ccgccgccga tcagggcgac ccgccgcggc gccgcgccgt
    18121 cgtcgcggct catcgcgcgc gctccttccg gtacgccgcg gcgctcgcga cgagcccctc
    18181 cggcacgagc gggttggacg cccagtgggc gtggacgtag gaggcgagca cgctctgcgt
    18241 ccagtagccc tcgcgcgcga cctggccgcc gcgccggcgg cgcacggagt aggcgtgctc
    18301 gatcggcagg ggcggggagg acgtcgcggg cgcgggcgca ggagacgccg cgggcgcggg
    18361 cggcgagggg gcgggggtcg acggcgaggc cggcgccgat gccgccgggg acgcgggcga
    18421 cacggggcgg agctcggagt agcggaactg atggccgcgg aagcggagcc cggcctggcc
    18481 gaggatcgtg cgcgcctgcg tctccacctc gacgtacccg agcgcctgaa gccgctcgca
    18541 catcacggcc tccgcgggga tgagcccgac catcgggtgc gctcgcccgt cgagggtgcg
    18601 gatcgcctcg gcgaggacca tgagcccgcc gcactcggcg tagatcgggc ccccgccgcc
    18661 ggcgaacgcg cggatctcgg cgcgcatcgc ggcgttctcg gccaggcgct ccgcgtgcac
    18721 ctccgggtac cccccgccga ggtaaagcgc gtccacgtcg ggcaggcgca cgtcgcgcag
    18781 cggcgagaac cggacgagct cggccccggc ggcctcgagg cggcgcagat tgtccgcgta
    18841 gtagaagtgg aaggcctcgt cgaaggcgac gccgatccgc gccgcgcgcg gccgagcgcc
    18901 gggcggatcg acgcgcggtt cgccggacac cgtcgccgcc ctcgccggag gcggcgacgg
    18961 cggcggcgac ggcaaggccg gcgccccgcg cgcgatctcg agcagcgcgt cgagcccgat
    19021 ccattcctcg gcccgcgccc cccagtggtc caggcgctcc tcggggagcg ccgcctcgtc
    19081 ggcggtgcgc agcccgaggt ggcgctcggg gaagcgctgc gcctcgtccc gcggcagccc
    19141 gccgagcacc ggcggcgagc gctgcgcctg ccgcaggagg tcgaggtggc cccggctgcc
    19201 gacctggttg cacacgaccc cggcgacgcg gagccccggg tcgaaggtcg cgaagccctg
    19261 caccagcgcc gcgatgctgc gggccatgcc ggacgcgtcg gcgacgagca cgaccggcgc
    19321 ctcgagccac ttcgcgatct cggccgtgga gccctcctcg cccgcggggc tcgcgccgtc
    19381 gaacagcccc atcacgccct cgaggagcgc gacgtcggcg cccgcggact cctccgcgaa
    19441 cgtggacagc acggcgtccc ggcccatcat ccagccgtcg aggttgtgcg acgcgcccgc
    19501 gatcgcgcgc gcgtggtacg tcggatccag gtagtcgggg ccgcacttga agagcgcgac
    19561 ccggaggccg cgcgcccgga gcgcacgcgc gatcgccacc gtgacggtcg tcttgccgac
    19621 gccgctcgcg acgccggcga cgacgagccg ggggatctgc cgggacatca gaagtcgact
    19681 ccgatctggg ccttcatccc ctgcgcgaac gggtgcttga ccgacttcat ctcggtcacc
    19741 aggtccgcga gctcgacgag cgcgtcgggc gcgttcctgc cggtgatcac gacgtgcacg
    19801 tgcgccggcc gcccgcgcag cgccgagagc agctcgccct cggcgatgaa gccgtagtgg
    19861 atcgcatacg tgatctcgtc gagcaccacg atgtcgtgct ccccgcccgc gatgagcgcc
    19921 gcggcctcgt cgaaggcggc gcgcgccgcc gccttgtccc gcgagaggtc gtcgctctcc
    19981 caggtgaagc cgcgccccat cacgaggaag gtgaggccgg ggagcgtctc ggcgaacagg
    20041 cgctctcccg tcttccactt ccccttgatg aactgcacga ccgcgacgcg catgccccgc
    20101 ccgagcgcgc ggaacaccat cccgagcgcc gccgtcgtct tgcccttgcc gtggccggta
    20161 tagacgatga cgagccctct cttctccgcc gcctccgccg cccccggcgc ctccgccccc
    20221 gcgctcacga cccgtcctcc gccgggccgg acgcgcgccg cttctcggcc ttgcggaacc
    20281 ggtggctgaa ctccggatcg tagagccgcg agtcggcgaa atccgtggcg gtgagcacgc
    20341 ggccgaccag gatcatcgac tggctcttga tcccctcggc gcgcaccttc tcccggatgt
    20401 cggcgagcgt gcccgtcacg atcttctgat cggggcagct cgccttgtgc accaccgcga
    20461 ccgggcagtc ggcgccgtac gacgggatca gcgcctcggc gacgtccttg agcaacgtga
    20521 tgctcaggaa gaggcagagc gtcgcctggt ggcgggcgag ctcctcgagc cgctccgcgg
    20581 gcgggaccgg cgtgcggccc tcggcgcgcg tcaggatcac cgtctgcgag agctcgggca
    20641 gcgtgagctc gcgcccgagc gccgccgccg ccgcggtgaa cgacgagacg ccggggatga
    20701 tctcgtacgg gatgccgagc gcctccagcc ggcgcatctg ctcggcggtc gacccgaaca
    20761 ggaccggatc gccggtgtgc acgcgcgcca cgtcgtggcc cgcctccttc gcctcgacga
    20821 agaccgccac gatctggtcg agggtcatgc cggaagagtc gatgacccgg gcgtccggcc
    20881 gcgcggaggc cacgacctcc cgcggcacga gggagcccgt gtacaggacg acggggcagc
    20941 gggcgacgag ctcggcgccg cggacggtga tgagcccggg atcgcccggg ccagcgccga
    21001 tgatgtaaac gcgcatgagg gatctccagc tagatgcagc gcagcacgtt gtcgcgcacg
    21061 agctgccaga tggcctcggg gatgtcgccg agccaccggg cgtcgcgctc gatcggctcc
    21121 tccgggtcgt cgagcgggtc gtcaggggag tagacgagcc gccagagccg ctcgctcacc
    21181 gagccgttcc gctcgatcag gaagcgctgc gcgaggcgcc gcgcgagctc ctcgccctcg
    21241 acgtcgagca gcagcaccgg cgcggcgacc ttcacctccc gcagcggcag cagctggaca
    21301 tacggcttct tcagcgcgtc gatctcgccc ggcggctcga accccgcctg ctggaaatcg
    21361 cacggcacct tggtgttgcc gatgaggtaa tacgtcccct gggtctcggc gagcagcgcg
    21421 ccgcccagcc ttcctacacg cgccatctta gacctcctcc gcagcggcgc cctcgtccga
    21481 gagcaccagc gagcgccccg gcgtctggcc cgggagcgcg gctccatccc atgtgtactt
    21541 gttggtgtat ccgcgcggcg tgaccatgta tccctcgaac atgaaggtgt tggtcgaccc
    21601 gacgagcacc gtggtcagca taccgatctc gtactccagg aagtgatcga gatcggtgag
    21661 cacggcgctc tccagcttcc tgtaagcgct cttcacgagc gcgaccgggg tcgtgcccgc
    21721 gcggtgctgc gcgatgatct cctgggcccg gacgatctgg cgcgtgcgcc ggccgctcgc
    21781 gggattgtaa aggccaatga cgaagtcggc cgcggcggcg gcctcgagcc tgcgctcgat
    21841 gaccggccac ggggtcagga ggtccgagag cgagatggcg cagaagtcgt gcccgagcgg
    21901 ggcgccgacg agcgacgcgc acgcgttcag cgcggtcatg ccgggcacga tgcggagctc
    21961 cggcgagccg ccccgcttcc agccgatctc ctggagcacc tggaagacga gcccggccat
    22021 gccgtacacg cccgcgtcgc ccgacgagat gatcgcgacg cgcgccccgt cccgcgcccg
    22081 ctccaccgcg gcgcgggcgc ggccgatctc ctcggtcatc ccggtcttga tcacctcctt
    22141 gccctggatg aggtgcttca ccagccggat gtaggtcgtg taccccacga tgaggtccga
    22201 ggcggcgatc gcctcgagcg cggcgcggga cgcgtgctcc tcggcgcctg ggccgatgcc
    22261 gacgatggac aggactccgt gctcagccat ggctctcctc gacggtgcgc ttcgggaagg
    22321 ggacacgcgc gacggcgagc gtcatggacc gccccgcgcc ctcctcggtg tacgcgcgct
    22381 tcgggacgag cagcctggcc gcgcccgcgg cgcgcagcgc ggcgggctcg gcgacgcccc
    22441 gggcgccgac gtgcttcttc acggtctccg acgggttctc gatcccctcg gtcgcgtcga
    22501 gctcctcggc ggtgaacgtg acgagcggcc agccccgccg ctccgacagc gcgagcagcg
    22561 cctcctcgtc cgccttcttg tcgatggtcg cgagcgcctt gaccgacttc gccgacagcc
    22621 cgtgctccgc gagcagcttg tcgaccccgc gctccaccat gtcgagcggg gcgccgcggt
    22681 cgcagccgac gccgagcacg aggctcttcg ggcggtagac gacggcgcgc tcgacgacgg
    22741 cgggatgcga gcgcgcgaga tcgcggtcgc tcgcgacgag caggatctcc caggcgtctg
    22801 gatcgacgcc gtcgagcgac gtcgcgtagc ggacgccggg cgggagcggc gtcgcctcgg
    22861 gccagaacga cggctcgccc gcctcctgga cgaacagcac gggcgcggcg ttcacgaccg
    22921 cggcgcagcc gcgcgtcacg ttgcggtcgg ggtcgtcgag cgtccagccg agctcccggc
    22981 cgaggatgtc gaccgtcagc gtcccgagcg cgtcggacgc ggtggtcacc accggcaacg
    23041 cgccgagcag cgcggccacc ttctcggtga acgcgttgcc ccgcccgacg tggccggaga
    23101 gcacgcagat cgagaagcgg gcggtgtcgt cgacgcacac gaccgccggg tcgaccttct
    23161 tgttcttgag gagcggagcg atcatccgca ccacggcgcc gacgctgatc acgaagacgt
    23221 ggcagtcgta ggccgtgaag gcctcggtga gcagcggacc catcggcagc gggagcggct
    23281 tcgccccggc cggcgccgcg tcgaagagct tctgcgagac gtagagatcc gcgcccggca
    23341 gcccctcgag cagcgtgcgg ccgatggcga tcccgtggcg cgtgatcgcg tagacggcgt
    23401 acggcttgcg cgcggcggtc acggcgcctc cggttcgtca agggtcttgc cgaaggcgcc
    23461 cggcggcgag gcctcggcct ccccgacgag cagcccgctg cgctccccgc gcgtgaccac
    23521 caccatggcg aagcagtcgc cccgctcgcc ctgcgcggcc cggaggtccc ggacgatccg
    23581 ctgctcgggc atcgtcgcct tggacacgaa caccgcccga tcgagcaggc ccgcccgggt
    23641 gagcgcctcg gtgaccttcg gcatctccga gccgatcttc atcaggacca cggtgtcgaa
    23701 gcgctggagc acctcggtga ggtcgtcgac gcc
//
