LOCUS       NZ_PSVY01000008        20309 bp    DNA     linear   CON 18-SEP-2024
DEFINITION  Rathayibacter sp. AY1D1 AY1D1_8, whole genome shotgun sequence.
ACCESSION   NZ_PSVY01000008
VERSION     NZ_PSVY01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Rathayibacter sp. AY1D1
  ORGANISM  Rathayibacter sp. AY1D1
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Microbacteriaceae; Rathayibacter.
REFERENCE   1  (bases 1 to 128170)
  AUTHORS   Davis,E.W. II, Tabima,J.F., Weisberg,A.J., Lopes,L.D., Wiseman,M.S.,
            Wiseman,M.S., Pupko,T., Belcher,M.S., Sechler,A.J., Tancos,M.A.,
            Schroeder,B.K., Murray,T.D., Luster,D.G., Schneider,W.L., Rogers,E.,
            Andreote,F.D., Grunwald,N.J., Putnam,M.L. and Chang,J.H.
  TITLE     Bacteriophage NCPPB3778 and a type I-E CRISPR drive the evolution of
            the US Biological Select Agent, Rathayibacter toxicus
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 128170)
  AUTHORS   Davis,E.W. II, Tabima,J.F., Weisberg,A.J., Lopes,L.D., Wiseman,M.S.,
            Wiseman,M.S., Pupko,T., Belcher,M.S., Sechler,A.J., Tancos,M.A.,
            Schroeder,B.K., Murray,T.D., Luster,D.G., Schneider,W.L., Rogers,E.,
            Andreote,F.D., Grunwald,N.J., Putnam,M.L. and Chang,J.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2018) Botany & Plant Pathology, Oregon State
            University, 2082 Cordley Hall, Corvallis, OR 97331, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-NOV-2017
            Assembly Method                   :: SPAdes v. 3.11.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 161.699x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002932635.1-RS_2024_09_18
            Annotation Date                   :: 09/18/2024 02:01:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,548
            CDSs (total)                      :: 3,497
            Genes (coding)                    :: 3,463
            CDSs (with protein)               :: 3,463
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 34
            CDSs (without protein)            :: 34
            Pseudo Genes (ambiguous residues) :: 0 of 34
            Pseudo Genes (frameshifted)       :: 6 of 34
            Pseudo Genes (incomplete)         :: 27 of 34
            Pseudo Genes (internal stop)      :: 3 of 34
            Pseudo Genes (multiple problems)  :: 2 of 34
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:54:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 54397
            Orig. end                         :: 74706
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PSVY01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20309
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20309
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20309
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10309](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10309
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(519..533)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.85"
                     /tool="antismash"
     gene            1690..2763
                     /locus_tag="C5C56_RS07895"
                     /old_locus_tag="C5C56_07895"
     CDS             1690..2763
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025072.5"
                     /locus_tag="C5C56_RS07895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_07895"
                     /product="glycosyltransferase"
                     /protein_id="WP_104262617.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 3.7e-09,
                     bitscore: 29.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRALFSVKDFSGSSNPYIELLVGSFPASVEPVAFTWRRALLGRY
                     DVFHVHWPEYLFRAPRGPRRWLKSALAFGLIARLLASGTPVVVTMHNLRPHESGSAVET
                     LLARWLDRLTDVRIYLNESDENDLDRGVVVLHGAYPESASVPGPREAGRRILFFGQIRP
                     YKGLEELIAAFSALTDGELVIAGAAAVPEYADEVRRAVGADGRVHLRLGHIDDAELDEL
                     LAGADLVTLPYKYLYNSGAALLALGARKTILVPATGSTRALAAEVGSGWVELFDGLVSP
                     AALEAGLERARRHGERERPDLSKRERSLVGALHGAVYEALVAAGRGRGRGGKGRRAATL
                     ARLRADPRFLRHSELNR"
     gene            complement(3003..4121)
                     /locus_tag="C5C56_RS07900"
                     /old_locus_tag="C5C56_07900"
     CDS             complement(3003..4121)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025072.5"
                     /locus_tag="C5C56_RS07900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_07900"
                     /product="glycosyltransferase"
                     /protein_id="WP_104262618.1"
                     /transl_table=11
                     /translation="MKIVFASHTAEVGVFRVGSHHLARELSRLGNTVTHVSTPSSLLHA
                     GRLRDATVRARFGLALRGPRTDAAGVVHAEPLTVAPLGSLPARMRTPSLRVPLRPWRAP
                     SGAMRPDVLIVDQPLMGVPLLELLQPKRVVYRPTDAHFEPGMRAAEIELLERADALVAT
                     SEPVLRAVSEGVAAPERTLVLENGVEYERFHGLGAERAGVVYLGALDRRFDWGGVRMLA
                     SAFPDVPFRLAGPLPKNVETLPANVELLGAVPYSRAPALLKSARVGLLPLSDDPGNAGR
                     SPMKYFEYLAAGLRIVSSASPALRARSAPGVWLYDDPAGAENGLRSALEAAASGPNREG
                     SVYAEQYGWHRRAADLAQLLDAVLAAPRRVRR"
     gene            complement(4118..5254)
                     /locus_tag="C5C56_RS07905"
                     /old_locus_tag="C5C56_07905"
     CDS             complement(4118..5254)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016145.5"
                     /locus_tag="C5C56_RS07905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_07905"
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="WP_181027183.1"
                     /transl_table=11
                     /translation="MRVTIVHAYSTTNSGDGLLVEEARELVLSALPTAEITLVALDPAS
                     FDEELYESVLHPLTGRAGSIGSLETLRRGGVALLSGRRSAGYARAIAGSDLVVGVGGGY
                     LRTKNPVEVVKMMCTNFVQMPRRSDRVPFVYLPQSIGPLNLGTRRVIAARLARAVGVFA
                     RDDRSVEELSGLANVHRAPDMALLGLPDEFDPRTVVRAGAPGPVGIVARALSSSRSRRA
                     AYESRIDALARDPESELLAQATARGNNDPQFYERLGHEGPFRLLRDAVGSGVADRPAVV
                     VSVRLHGSIQTIRSGVPSVHLSYERKGWGAYDDLGIDRFVHNAFDADLSLIRDQIAELR
                     EDPSDYWRRVGDSVSALRMQRGRLVDLLVDASGPVGRP"
     gene            complement(5251..6309)
                     /locus_tag="C5C56_RS07910"
                     /old_locus_tag="C5C56_07910"
     CDS             complement(5251..6309)
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012744.5"
                     /locus_tag="C5C56_RS07910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_07910"
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="WP_104225715.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 6.5e-27,
                     bitscore: 87.1, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVLVSARVLDRQVGGNTRYARTVYSGLAGHGVQHVLSRPPIEG
                     GRARSAVYGAYEGLVLPRLRPSGIDVLHFPADTGPLVPSRLPIVGTIHGLATLHVDDVR
                     SRSSDRLWRLRVARLAALSTTIITVSDSSARDIATVAPDAAGKIVTIPHGIDHDTFNTR
                     STDQDSVALDELGIDGPYFLYAGNLDPRKNIIELCRAASKVFDETGVPLLVSGAPAWES
                     DAILEAVRGTRGVRYLGRVPDEALVPLLRGALAFCFPSTYEGFGFPVVEAMACGVPVIC
                     SDRGSLAEVAGGAALTLTDIGATAIADHMREIVADPSLRNDLRSRGLINARRFHWSDSI
                     AAHARVFEEAAR"
     gene            complement(6306..7793)
                     /locus_tag="C5C56_RS07915"
                     /old_locus_tag="C5C56_07915"
     CDS             complement(6306..7793)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024831.5"
                     /locus_tag="C5C56_RS07915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_07915"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_104319374.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 6.6e-12,
                     bitscore: 38.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSACWNGMKTMARNRSRWTTSRRAAPSRVVAVAAPPRAISRLIS
                     DVIDHRSSPAAAPFSSVGLQTNHGPGPPEVVPFRPHTVGREHIGSLTESCRRTAWSVRD
                     PVRWSSTGTGAFHGSAKPEGRERLTSGSTLAEDWREGERTIVHVTESFGAGTASAISDY
                     VAATPAFQHRLVYSPREDSPVPESAFASFAGVTALPTGHVARVRALRTVLAGMPGAVVH
                     AHSSFGGAYARLAVRAGRRRPIVYTPHCYGFERRDLPLPARAAFRVFEGVLAFNTTVFA
                     ACSAREARLSRWPFSRAEVVHVPNSVPASLPPATRPGGPRPLRLVGAGRLSTHKDPRFF
                     AEAVEAVRAAGHSVDATWIGGGEGRHRTALDQAGVHVTGWLSRDEALRRLGDADVYLHS
                     AQWEGMPMAVLEAHGMGLALVVRDIPAFDRLGLPLVAHSPHDVASYWGDLEDPAARSRL
                     VAAAEHALALNTVQHQSQMLERLYLGLLPTAPRRRKP"
     gene            7675..9072
                     /locus_tag="C5C56_RS07920"
                     /old_locus_tag="C5C56_07920"
     CDS             7675..9072
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016800.5"
                     /locus_tag="C5C56_RS07920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_07920"
                     /product="O-antigen ligase"
                     /protein_id="WP_181065640.1"
                     /sec_met_domain="Wzy_C (E-value: 1.3e-14, bitscore: 47.4,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARGGAATATTREGAARLDVVQRLLFLAIVFMPFQQALTIQVGSP
                     LKITEIAVILAIGFSVITVQKDRYTPVGREIVLGLGALVVLATIWAFLFKQPEVPAAYG
                     YDLGFTNDMILYCGYALLALAVWWYVGHRLGFQDMERALSIAVRLAFVFCAIQLALHLA
                     GVPLPALLNSTIQMGATFGVSLPRNGPFLEGNYLGFFAGIALFACLRRRDRIGIAAAVA
                     CLVYSQSTSALIATVSAAVLTATLRPQRGVGVQIFSVGALGAVIVLLVPALQRFVLAQL
                     SKLGLGTGAVDVGTRSLNVRSQSSSTGFTMAADNPLFGVGPGRFGVWRTDYSQAVAGLT
                     SNGASRGLANNVYAQLAAETGVIALALFAVLLVMLIVRGYRRNGTALGLGVFLAVALAS
                     APAWTALTVWIALAYAASLASEPLPATTSIARSGLDSERRAAAVSRSMAVRPAPSTGRH
                     RQLSDRR"
     gene            9069..10004
                     /locus_tag="C5C56_RS17795"
     CDS             9069..10004
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.5"
                     /locus_tag="C5C56_RS17795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_181027180.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 8.9e-17, bitscore:
                     54.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSAPATTELSLDDAVHLAHALTAHLSSTHGLRALFIKGPTAHAQ
                     GIRTRRVSSDVDVLVHPADVQRLVDLLAERGWIPRPDRPAPRAYPVHSVTLFHPQWTCD
                     IDVHDRYPGFFAEPEEVLDVLWTSHRTVTIAHRRVAVPSPVAGAVVVALHALKDPLLAR
                     STSELESVIGFLRGASESDREALLLLVESTRSAYPLRPVLHALGLDVPDDLAVHERRLW
                     DLRVAGTGRSSYHWALAFVEATGKRRIVLIVSALTTVIGLTRRARRRAAETGMVRFDRP
                     SLSDLRAFLGLVRSLAADRRRRRRENATHS"
     gene            10001..10309
                     /locus_tag="C5C56_RS17800"
     CDS             10001..10309
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="C5C56_RS17800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_181027179.1"
                     /sec_met_domain="PF05402 (E-value: 3.1e-13, bitscore: 42.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.3e-11,
                     bitscore: 35.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVDPGALDHAVWARSDQLAFVEDDAQAVLLNLLSPFPVPLVLK
                     GTAHAIWRRLEHPSTTVEILAGLADEFGVPREVLEEDVLSFLLELSTADVVHRLPSR"
     aSDomain        10130..10294
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C5C56_RS17800_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.50E-11"
                     /identifier="RREFam002.1"
                     /label="C5C56_RS17800"
                     /locus_tag="C5C56_RS17800"
                     /protein_end="98"
                     /protein_start="43"
                     /score="35.1"
                     /tool="antismash"
                     /translation="LKGTAHAIWRRLEHPSTTVEILAGLADEFGVPREVLEEDVLSFLL
                     ELSTADVVHR"
     gene            10477..11979
                     /locus_tag="C5C56_RS07935"
                     /old_locus_tag="C5C56_07935"
     CDS             10477..11979
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C5C56_RS07935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C5C56_07935"
                     /product="hypothetical protein"
                     /protein_id="WP_146078929.1"
                     /transl_table=11
                     /translation="MATAPPATAANAFPDARLDGFRDSTEFPGATAEQRLRAALDAAHA
                     LTTESFLVVSEPVVLTAPLTIDLSRVSMEFAGGDVDATAVSGSALVLTASEASDDAPHT
                     RVSLRGLRLTGPGRAAPGSVGLELSSATGVRGAGLYGVEIIGFETGVRFGPGAEHLRLF
                     HVAVEECGTGVLVAGTAPGSNLAMVGGSVRSCTTGLSSASTSGELHTTSLAISGCDRAV
                     EASGGAVTLHAATVRLTPASTVSAFSTAATTTARISINGGTVSAAAPLAAATVFETAHR
                     SWGGGIVVTSTSFRNVAPASGYLVGGTGLVRLADVSILDEPSVVPTSVLVHRAANRLVD
                     GAFDLGTVADAYLDTPDATSRSASPSATLAVASGRLLVRKTGTGQTSLSFDVLSRPGQV
                     YAADLVIGQAAANGSMIVSESFVTVSGRDARGIPVTVRSEPVSSTTQSMAAMAAALPFR
                     VRPATGVDRQAPSWASHFRVTVGLNDPAAGTVGIDDAVVTEM"
     gene            complement(12011..13441)
                     /locus_tag="C5C56_RS07940"
                     /old_locus_tag="C5C56_07940"
     CDS             complement(12011..13441)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146: sugar transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005050459.1"
                     /locus_tag="C5C56_RS07940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_07940"
                     /product="sugar transferase"
                     /protein_id="WP_258059309.1"
                     /sec_met_domain="Bac_transf (E-value: 3.2e-71, bitscore:
                     231.4, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARKLVITDVLVIVFSVFSSQFFWFGVESRELFVAGHQPEIAGLL
                     ANYWIVSSMIVVLWAALLKFYATREDRVLGGEVTEYKRILDATLLLFAVITCVAYLGQI
                     GFARGYIITALPLGLVLLWLGRGAWRVWLRQQRSAGRYSSSVVLVGSPRSVEHIYRELV
                     RAPGAGYLVVGVCIPEDLASDRVSGWGVPVFENITVDAVPGILNRTGADTVIITSSDHL
                     PPEQIRQLSWSLEPRRQHLVMAPSLTDISGPRIHMRPVAGLPLVHIETPRFEGSKQARK
                     RALDIVGSLSLIAVLMPLIASVALAVKLTSSGPLFYRQTRIGINGKPFGMIKFRSMVVN
                     AHDQLAELLAAQGTSGTPLFKITDDPRITPIGRFMRKYSIDEVPQLFNVLRGDMSLVGP
                     RPQVAGEVELYDEAARRRLNVKPGMTGLWQVSGRSTLSWEDAIRLDLYYVENWSFTGDL
                     ALLARTVQAVVAPGGGAH"
     gene            complement(14485..15864)
                     /locus_tag="C5C56_RS07950"
                     /old_locus_tag="C5C56_07950"
     CDS             complement(14485..15864)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C5C56_RS07950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C5C56_07950"
                     /product="hypothetical protein"
                     /protein_id="WP_146078822.1"
                     /transl_table=11
                     /translation="MSNTSPSDSPVPARNAVPGRRTVLQAAAWTTPVVVAAIGAPLAAA
                     SAPVTVRTVAFVDQEGGDATTSYTTSSCNPFNAYLQVSDSGVPAAAGIAVTVTLPTALR
                     WYDGTATPRTLFTGAGGSLLLEGFNGLRFATAGVSQTGTITATTAGVVNPAQPTVPVAD
                     ATTAAIVNGTSGTRTSTFRGRRNNVESEMPEAVTTVVDFAVAWTGVGDTAASATYLSYV
                     VSQDGDVYSHTAPSGGFYEWDTTTPIRIGMTSIAADDGLIIAGGDRGARLFSASGSTVY
                     DWDGVALAAAPGGRTVLDIAVSFSDDSLWRVSLVATDGTAWEATKTIEAGASWSPWTQV
                     LATVTGLRQVAADTQVFGATRRIFATTAAVFDQDGTQLTALPAGRTAKDLGVEIGGNWI
                     NVIGDNNQYYRTPLSNPGTWDSNSTGSPVVTITNVTSVASASTPNIGIRAFYVAGAALC
                     G"
     gene            16719..17102
                     /locus_tag="C5C56_RS07955"
                     /old_locus_tag="C5C56_07955"
     CDS             16719..17102
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1198: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF016152.5"
                     /locus_tag="C5C56_RS07955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_07955"
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="WP_104222787.1"
                     /transl_table=11
                     /translation="MDDTAVRRLLEGLAGAEASFPFGPGTRVWKVAGKVFALESERFER
                     PVVSVKALPENVVHLVAGVEGIEPGYHLNKKHWVTVDAGGAVESGLVLELIEESHAIVV
                     AGLPKRLRLALGGTAAGSLNEDR"
     gene            complement(17169..17921)
                     /locus_tag="C5C56_RS07960"
                     /old_locus_tag="C5C56_07960"
     CDS             complement(17169..17921)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018172644.1"
                     /locus_tag="C5C56_RS07960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_07960"
                     /product="HAD-IIB family hydrolase"
                     /protein_id="WP_104222786.1"
                     /transl_table=11
                     /translation="MSTLPRLMAFDLDDTLAASKSPVDPAMADLFVKLLQATEVCIISG
                     GQIGQFRMQVLDRLEGADPEVLAKLHLMPTCGTQYYRYENGDWAQIYAENLTEDEKSRA
                     LAAVEEKAKELGYWESETWGPILEDRDSQITFSALGQSAPVEVKQAWDPDGEKKNTLRE
                     AVQAVLPDLEVRSGGSTSVDITRKGIDKAYGMNKLTELTGIPLDDMIFVGDRLDPDGND
                     YPVKAMGVECFAVEGWHDTAAYLRSYGL"
     gene            18027..18479
                     /locus_tag="C5C56_RS07965"
                     /old_locus_tag="C5C56_07965"
     CDS             18027..18479
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017831824.1"
                     /locus_tag="C5C56_RS07965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_07965"
                     /product="DoxX family membrane protein"
                     /protein_id="WP_104250678.1"
                     /transl_table=11
                     /translation="MTAATAPDGGRRSVPRTLARILLGLVLVTAGSAHLTVARQAFQAQ
                     VPPWLPADPDLVVVASGVVEIALGLALVVLVRWRVIVGVVVAAFFVAVFPGNISQLVTR
                     TPAFGLETDAARAVRLVFQPLLVVWALWSTGAFSAWRARRSRRRGD"
ORIGIN
        1 ccgcgtcaac ggaatccaca actacctcga attcgccggg accactgacg aggacaagct
       61 ccgcgccgcg atcgactatt tcgtcgccgc tcgccaagag gtcacgttga cgatctcgaa
      121 gagcttcaag atcacgcgca ccctcgtgat cgactcctcg tacatctcgc tcgagttcac
      181 ctgcggtccg ctgaatgcga ccgccatcac cagcggtcct gctctcacgg tgatcggcag
      241 tgccacgtcc ggctacccca acaacagggc ggcgatcacc ggactccgtc tgctggggcc
      301 gggagcgtcc gcgacggcca gcaccggaat cctgttcaac accgacagca cgactgccgc
      361 caccacgcgc gggctcggac tctggggcct ggagatctcg ggcttcggga ccggcgtgtc
      421 cttcgagaac gatgcgttcc tgatcagctt ctacaacttc cacatcttcc gctgcaggac
      481 ggccgtttcc atgcccgcag gcagagtcaa ctacggcgag aacatcaagt tcatcggcgg
      541 tggtatcggc accagcaccc tcggcgtcta caacgccaac ccgaacggcg agctgcactt
      601 cgtctcgacg tcgatcgact tctgcgtgca ggccgtgaag gtcgacgcgg gtcgggtgat
      661 cctgcaccag ccgcatatcg agatcaacga gagcggcgcg aactccacgc tctcgcagtt
      721 cgtcaccggg tcgagtacag ctgcgcagat ctcgatctca ggcggacacc tcttcttcca
      781 tcaggtcccg gtggccaact acctcttcga gaccactgca ggagggtggg gcggcggaat
      841 ccaggtccat caactgtcga tgttcaatac gcagatgaaa tcgggatatc tcgccggtgg
      901 cactgcgaag gtccgtatca gccagcacgt cacctcggac gggaacggca gcggttcggg
      961 gcaggggtcg attctgcatt cgaaggcggc gaacaagctc gtcgacggga acttctctct
     1021 cgcagcgccc gtcgacgcgt tcctcaacgg cgccgacgcg acgagccgca ccaccagccc
     1081 gtccatgacg ctgaccacca gcggcaacca gctgctgatg acccgagtgg ccggcggtcc
     1141 cggtccggcg gtctccatcg acgtccccgt cacagcgggg ctgctgtacg gcgtcgactt
     1201 caccatcgcg ggatccacgt cgacgggcac gatgtacgtg tccgaatcct tcgtcgccgt
     1261 gaccggcgtg tcctcgtcgg ggatcccgat cgtcgctcgg agcagcgctc gcccggtgtc
     1321 gaatctcgac ctcgccggcg cgaacgcgca ggctcccttc cgcaagacct atcagcagac
     1381 gacctggaac cgggtcgctc ctgcgtgggc gacgcacttc cggctgcggt tcaccttcgg
     1441 atcggtgaca gcaggagtga ctcgcttctc ggagatcgtc atcaccgaac tctgacgggg
     1501 gcggcgggtg acggacctcg agaaacccga ctggtagcgt cagaccatcc ctcgccggcc
     1561 gaggtcgtcc gctccgtcgc cgaagcgggc gtgtcgcggt ccgatcacag gccgtggtgc
     1621 cctctcccat gtcgtctcgt ggtgcccggg gcggtccgcc gaagagacga acgaaggaga
     1681 agcacgcgaa tgatccgggc gctcttctcc gtgaaggact tctccggctc gagcaacccc
     1741 tacatcgagc tgctcgtcgg ttcgttcccg gcgtcggtgg aaccggtcgc gttcacctgg
     1801 cgacgtgccc ttctcgggcg ctacgacgtc ttccacgtgc actggccgga gtacctcttc
     1861 cgtgccccgc gcggtccgcg ccgctggctg aagtccgccc tcgccttcgg gctcatcgcc
     1921 cggctgctcg cgtcggggac gccggtcgtc gtgacgatgc acaacctccg accgcacgaa
     1981 tcgggcagtg ccgtcgagac tctcctcgcg cgctggctgg accggctcac ggacgtccgc
     2041 atctatctga acgagtccga cgagaacgac ctggaccggg gagtcgtcgt cctgcacggc
     2101 gcctatccgg agtcggcctc tgtcccgggc ccccgtgaag cgggtcggcg catcctgttc
     2161 ttcgggcaga tccggcccta caagggactc gaggagctga tcgcggcctt cagcgcactc
     2221 accgacggcg aactcgtcat cgccggcgcg gccgctgtcc ccgagtacgc cgacgaggtg
     2281 cgcagagcgg tcggagccga cggtcgcgtc cacctgcggc tcggccacat cgacgacgcc
     2341 gagctggacg agctcctggc aggcgcggac ctcgtcaccc tgccgtacaa gtacctctac
     2401 aactccggag ccgcgctgct cgccctcggc gcgcggaaga cgatcctggt cccggcgacc
     2461 ggatcgacgc gggccctcgc cgcggaggtc gggagcggct gggtggagct gttcgacggc
     2521 ctcgtgtcgc cggcggcgtt ggaggcgggc ctcgagcgag cgcgccggca cggagagagg
     2581 gagcgacccg acctgtccaa gcgcgagcgt tccctcgtgg gagcgctgca cggcgccgtg
     2641 tacgaggcgc tcgtcgctgc aggccgaggt cgaggacgag gcgggaaggg gaggagagcg
     2701 gcgacgctcg ctcgcctccg cgcagacccc cgcttcctcc ggcattccga gctgaatcga
     2761 tgaccgagcc gcagggagtc gaatgaggcg ttcagcgccg agccgccgtt cacgtaccag
     2821 gactacttcg aggggacagg acggaccggg tcggagtaca ccctcttcga tgatctcgac
     2881 tccgccgcgg ctcacgcgac gcggatccgg ctgcactcct agacgcccgc tggctgcgtg
     2941 ggatccggcg cccctgctgg acgccttccc gatcgaccgc tggcggcgct gaggacgggc
     3001 cgtcagcgcc gcactcggcg cggtgccgcc agcaccgcgt cgagcagctg tgcgaggtcg
     3061 gcggcgcgac ggtgccagcc gtactgctcc gcgtagaccg agccctcccg gttgggtccc
     3121 gacgccgcag cctccagcgc ggaccgcagc ccgttctctg cgcccgcagg gtcgtcgtag
     3181 agccagacgc cgggggcgga gcgggctcgc agtgcagggg aggcggacga gacgatcctg
     3241 aggccggcgg cgaggtactc gaagtacttc atcgggctgc gacccgcgtt gcccgggtcg
     3301 tccgagagcg ggagcagccc gacgcgggcg ctcttcagca gcgcgggcgc ccgggagtag
     3361 ggcacggcgc cgagcagctc cacgttcgcg ggcagcgtct ccacgttctt cgggagcgga
     3421 ccggcgagtc ggaaggggac gtcagggaac gccgaggcga gcatccggac tcctccccag
     3481 tcgaagcggc ggtcgagcgc cccgaggtag acgactcccg cacgctcggc accgagaccg
     3541 tggaaccgct cgtactcgac tccgttctcg aggaccagcg tgcgctccgg cgcggccact
     3601 ccctcggaga ccgcgcgcag caccggctcc gacgtggcga cgagagcgtc cgcccgctcg
     3661 aggagctcga tctccgccgc ccgcatcccc ggttcgaaat gagcgtccgt gggccggtag
     3721 acgacacgct tcggctgcag gagctcgagg agcggcacgc ccatcagggg ctggtcgacg
     3781 atgaggacat caggacgcat cgccccactg ggcgcccgcc agggccgcag cggcacccgc
     3841 agagacggcg tccgcatccg cgccgggagc gatcccagtg gggcgacggt gagcggttcg
     3901 gcgtgcacga cgcccgccgc gtccgtgcgt ggacctcgca gcgcaagacc gaagcgggcc
     3961 cgcacggtgg cgtcccgcag gcgccccgcg tgcaggagcg aggacggcgt cgagacgtgc
     4021 gtcaccgtgt tcccgaggcg cgagagctcg cgagccaggt ggtggctccc cactcggaag
     4081 accccgacct cggcggtgtg gctcgcgaag acgatcttca cgggcgcccg accggtccgg
     4141 aggcgtcgac gaggaggtcg acgagtcgtc ctcgctgcat ccgcagcgcc gacacggagt
     4201 ctccgacgcg cctccagtag tcggacgggt cctcccgcag ttcagcgatc tggtcgcgga
     4261 tgagcgagag atcggcgtcg aaggcgttgt gcacgaaccg gtcgatcccg aggtcgtcgt
     4321 aggcacccca gcccttccgc tcgtagctca gatggacact cggaacgccg ctgcggatgg
     4381 tctggatgct gccgtgcagc cggaccgaga ccacgaccgc cggccgatcc gcgaccccgc
     4441 tgccgaccgc gtcgcggagc aggcggaatg gcccttcgtg gccgagccgc tcgtagaact
     4501 gcggatcgtt gttgccgcga gcggtggctt gagcgagcag ctccgactcc ggatcgcgcg
     4561 cgagggcgtc gatccgcgac tcgtaggcgg cacgtcgcga ccggctcgag gacagcgcgc
     4621 gggcgacgat cccgacgggc ccgggagctc cggcccgcac gacggtcctc ggatcgaact
     4681 cgtcggggag gcccagaagg gccatgtcgg gagcgcggtg cacgttcgcg aggccggaca
     4741 gctcctcgac ggagcggtcg tcccgggcga agaccccgac ggcgcgggcc agtcgcgccg
     4801 cgatcacacg gcgggtcccg agattgagcg gcccgatgct ctgcggaagg tagacgaacg
     4861 gaacgcggtc gctgcgccgg ggcatctgga cgaagttggt gcacatcatc ttgacgactt
     4921 cgacgggatt cttggtgcgg aggtagccgc cccccacgcc gacgacgagg tcggacccgg
     4981 cgatcgcccg ggcgtagccg gcgctccggc ggccggagag cagcgcgacc ccaccgcgtc
     5041 gcagcgtctc gaggctgccg atgctgccgg cacggccggt gagggggtgc aggacactct
     5101 cgtagagctc ctcgtcgaag ctcgcgggat cgagggcgac gagcgtgatc tccgccgtcg
     5161 gcagggccga gaggaccagc tcccgcgcct cctcgacgag caggccgtcg ccggagttgg
     5221 tggtgctgta ggcgtggacg atcgtgaccc tcaccgcgcg gcctcctcga agacgcgagc
     5281 atgcgctgcg atggagtccg accagtggaa tcgtcgagcg ttgatcagac cccggctccg
     5341 caggtcgttg cggagggacg gatcggcgac gatctcgcgc atgtgatcgg cgatcgccgt
     5401 cgcgccgatg tcggtgagcg tcagcgccgc gccgcccgcc acctcggcga gcgacccgcg
     5461 atcgctgcag atgacgggaa cgccgcacgc catggcctcg acgaccggga agccgaagcc
     5521 ctcgtaggtg gaggggaagc agaaggcgag cgctccccgg agcagcggga cgagcgcctc
     5581 atccggtacg cggccgaggt agcgcacgcc gcgggttccg cggaccgcct cgaggatcgc
     5641 gtcgctctcc cacgccggag cgccggacac caggagcggc acccccgtct cgtcgaagac
     5701 cttcgaggcg gctcggcaca gctcgatgat gttcttgcgg gggtcgaggt tgcccgcgta
     5761 gaggaagtac gggccgtcga tccccagctc gtcgagcgcg acggagtcct ggtcggtgga
     5821 gcgggtgttg aacgtgtcgt ggtcgatccc gtgcgggatg gtgacgatct tcccggcggc
     5881 gtcgggtgcg acagtcgcga tgtcccgggc ggaggaatcg gagaccgtga tgatcgtggt
     5941 cgagagtgct gcgagacgcg cgacgcgcag gcgccacaac cggtcggagc tccggctgcg
     6001 cacatcgtcc acgtggagtg tcgccagccc gtggatcgtg ccgacgatcg ggaggcggct
     6061 cggaaccagc ggccccgtgt ccgcggggaa gtggaggacg tcgatcccgg aggggcggag
     6121 cctcggcagt acgagtccct cataggcgcc gtagacggcg ctgcgggctc ggcccccctc
     6181 gatcggaggt cgggacagca cgtgctgcac gccgtgtccg gcgagcccgc tgtagacggt
     6241 gcgggcgtag cgggtgttgc cgccgacctg tctgtcgagg acacgggcgg agacgagcac
     6301 tgtcgtcatg gcttcctcct ccgaggggcg gtcggcagca ggccgaggta gagccgctcg
     6361 agcatctgcg actggtgctg cacggtgttc agggcgaggg cgtgctcggc ggcggcgacg
     6421 agacgggaac gggccgccgg gtcctccaga tcgccccagt acgacgccac atcgtggggg
     6481 gagtgcgcga ccaggggcag gccgaggcga tcgaaggcgg ggatgtcccg cacgacgagg
     6541 gccagcccca tgccgtgcgc ctccagaacg gccatcggca tcccctccca ctgcgcgctg
     6601 tgcaggtaca cgtcggcatc gcccagtcgg cggagcgcct cgtcgcggct gagccagccg
     6661 gtgacgtgga cgccggcctg gtcgagggcg gtgcggtgac gcccctcgcc tccgccgatc
     6721 cacgtcgcgt cgacggaatg gccggcggcg cgcacggcct ccacggcctc ggcgaagaat
     6781 cggggatcct tgtgcgtcga gagccgaccg gcgccgacga ggcggagagg cctcggcccg
     6841 ccggggcgag tggcgggcgg gagcgaggcg ggcaccgagt tggggacgtg cacgacctcc
     6901 gcccggctga acggccaccg gctcagacgg gcctcgcgag ctgagcaggc ggcgaacacg
     6961 gtggtgttga aggcgaggac gccctcgaag acccggaacg ccgcccgggc gggcagcggg
     7021 aggtctcggc gctcgaagcc gtagcagtgc ggcgtgtaga cgatcggacg tcgccggccc
     7081 gcccggaccg cgaggcgcgc gtacgctccg ccgaagctgg agtgcgcgtg cacgacagcg
     7141 cccggcattc cggccagaac cgttcgcaga gcgcggactc gggcgacgtg ccctgtcggc
     7201 agcgccgtca cgcctgcgaa cgacgcgaag gcgctctccg gtaccggaga gtcctcccgc
     7261 ggtgaataca cgagcctgtg ctggaaggcg ggcgtggccg ctacgtagtc gctgatcgcc
     7321 gacgcggtac ctgcgccgaa gctctccgtc acgtgcacga tcgtgcgctc gccttcgcgc
     7381 cagtcctcag cgagtgtgga tccgcttgtc aaccgttcgc gcccttccgg cttggccgag
     7441 ccgtggaagg ctccggtccc tgtcgatgac catcggacag gatccctcac cgaccacgcg
     7501 gtccgtcggc atgactccgt gagcgatcct atgtgctccc ggccgacggt atgaggtcga
     7561 aaggggacca cctccggggg accgggaccg tggttagtct gtagtcctac agagctgaac
     7621 ggagctgctg caggagacga tcgatgatcg atcacgtcgg agatgaggcg cgagatggct
     7681 cgagggggcg ctgcgaccgc gacgacgcga gagggcgcgg cgcgtctgga tgtcgtccag
     7741 cggcttctgt tcctcgccat cgtcttcatg ccgttccagc aggcgctcac cattcaggtc
     7801 ggctctccgc tgaagatcac cgagatcgcc gtcatcctgg ccatcggctt ctccgtgatc
     7861 accgtccaga aggaccggta cacgccggtg ggacgggaga tcgtgctggg gctcggtgcg
     7921 ctggtcgttc tggcgacgat ctgggcattc ctgttcaagc aacccgaggt tccagccgcc
     7981 tacggctatg acctgggctt caccaacgac atgatcctct actgcggata cgctctgctg
     8041 gccctcgcgg tctggtggta cgtcggccac cgactgggat tccaggacat ggagcgggct
     8101 ctctcgatcg ccgtccgcct cgctttcgtc ttctgcgcga tccagctggc cctccacctc
     8161 gccggggtcc cgctgcccgc tctcctcaac tcgacgattc agatgggggc gaccttcggc
     8221 gtcagcctgc cgaggaacgg cccgttcctc gaggggaact acctcggttt cttcgccggg
     8281 atcgcgctgt tcgcctgcct gcgccgtcgc gaccgcatcg gaatcgccgc cgccgtcgcc
     8341 tgcctcgtct actcgcagtc gacgtcggca ctgatcgcga ccgtctctgc ggcggtcctc
     8401 acggcgacgc tccgccccca gcggggagtg ggagtgcaga tcttcagcgt cggcgcgctg
     8461 ggcgcggtga tcgtcctgct cgttcccgcc ctgcagcgct tcgtcctcgc gcagctctcg
     8521 aagctcggac tgggcacagg cgccgtcgac gtcggcaccc gctcgctgaa cgtccgatcc
     8581 cagtcgtcga gcacgggctt caccatggcc gcggacaatc cgctgttcgg agtcggaccc
     8641 ggccggttcg gcgtgtggag gaccgactac tcccaggcgg tggcggggct cacctcgaac
     8701 ggcgcctctc gcggtctcgc gaacaacgtc tacgcccagc tcgctgccga gaccggagtg
     8761 atcgccctgg ccctcttcgc cgtcctcctc gtgatgctga tcgtgcgggg atatcggcgc
     8821 aacgggacgg cactgggtct gggggtcttc ctcgccgtcg ctctggcctc cgcccccgcg
     8881 tggaccgcct tgaccgtgtg gatcgcgctg gcgtacgccg catcgctcgc ctccgagccg
     8941 ctgccggcga cgacctcgat cgcccggtcc ggcctcgact cggagcgacg ggcagcggcg
     9001 gtgtcgcgat ccatggcggt gcgtccggcg ccgtccaccg gtcggcaccg gcagttgtcg
     9061 gatcgacggt gagctccgca cccgcgacga ccgagctctc cctcgatgat gcggtacacc
     9121 tcgcacacgc cctcaccgcg cacctctcct ccacgcacgg gctccgcgcc ctgttcatca
     9181 aggggcccac cgcccatgca cagggcatcc gcacgagacg cgtgtccagc gatgtcgacg
     9241 tgctcgtcca cccggcggac gtccagcgcc tcgtcgacct gctggccgag cgcggatgga
     9301 tcccccggcc cgaccgcccg gccccgcgcg cgtacccggt gcactccgtg accctgttcc
     9361 atccgcagtg gacctgcgac atcgacgtgc acgaccgcta ccccggattc ttcgcagagc
     9421 cggaggaagt cctcgacgtg ctgtggacgt cgcaccggac cgtgacgatc gcgcacagga
     9481 gggtcgctgt gccctccccg gtcgcgggcg cggtcgtcgt cgcgctccac gcgctgaagg
     9541 atcccctcct tgcccggagc acgtccgagc tcgagtcggt catcgggttc ctcaggggcg
     9601 cgagcgaatc ggaccgggag gcgctgctcc tgctcgtcga gagcacccgc agcgcctacc
     9661 ccctccgccc ggtgctccac gccctcgggc tggacgtgcc ggacgacctg gccgtgcacg
     9721 agcgccggtt gtgggatctg cgggtggccg gaacggggcg gtccagctat cactgggcgc
     9781 tcgccttcgt cgaggccaca gggaagcggc gcatcgtgct gatcgtgtcc gcgctgacga
     9841 ccgtgatcgg tctcacacgc cgggcgcgcc ggagggctgc ggagacgggg atggtccgct
     9901 tcgatcggcc gtcgttgtca gatctgcggg cgttcctcgg gctcgtgcgc tcgctcgccg
     9961 ccgatcgtcg acgccgtcgc cgagagaatg cgacccactc gtgaccaccg tcgatccggg
    10021 agctctggat cacgccgtgt gggcgcgatc cgatcagctg gccttcgtcg aggacgacgc
    10081 gcaggcggtg ctgctgaacc tgttgtcgcc gtttcccgtg cccctcgtgc tgaagggcac
    10141 ggcgcacgcg atctggagaa ggctcgagca tccgtccacg accgtcgaga tcctcgcggg
    10201 gctcgccgac gagttcggcg tcccccgaga ggtcctcgag gaggacgtgc tcagtttcct
    10261 cctggagctg agcacagcag acgtggtcca caggctgccc tcgcgctgaa ggtgagacat
    10321 cgtgcagcag tgtgcgccgt gcggggggtg tgaacggcgg tcgtgacggc ggcctttcct
    10381 ccgtactgtt cgggaatggg agcatcatcg cgggatcgag gacgacgggc gctactgagc
    10441 ctgacggcgg cagcgggcgc gggcgccgtg acggcggtgg cgacggcccc cccggcgaca
    10501 gcggccaacg ccttcccgga cgcacggctg gacggcttcc gggactcgac cgagttcccg
    10561 ggagcgactg ctgagcagcg gctccgggcc gctctcgacg cggctcacgc cctcacgacc
    10621 gagtccttcc tcgtcgtctc cgagcccgtc gtgctgacag cacccttgac gatcgacctc
    10681 tcgcgtgtgt cgatggagtt cgccggaggc gatgtcgatg cgacggcggt gtcgggatct
    10741 gcgctcgtcc tcaccgcctc cgaggcctcc gacgatgcgc cgcacacgcg cgtgagcctg
    10801 cgcggactgc gcctcacggg tcccggccga gcggctcctg gatccgtcgg cctcgagctg
    10861 tcctcggcga caggcgtccg aggcgcagga ctgtacggag tggagatcat cggattcgag
    10921 acgggtgtcc ggttcggtcc cggcgccgag catctgcgcc tcttccacgt ggccgtggag
    10981 gagtgcggca cgggcgtcct ggtcgccggc actgccccag ggtcgaatct cgcgatggtc
    11041 ggcggttctg tgcgctcgtg cacgacggga ctgtcctccg cgtcgaccag tggcgaactg
    11101 cacacgacgt cgctggccat cagcggatgc gatcgcgcgg tcgaggcttc agggggtgcc
    11161 gtcacgctgc acgctgcgac cgtccgcctg accccggcga gcacggtcag cgcgttctcc
    11221 accgctgcga cgacgacggc caggatcagc atcaacggcg gcacggtctc cgccgccgcc
    11281 ccgctggcgg cggccacagt cttcgagacg gctcacagga gctggggagg cgggatcgtc
    11341 gtgacgagca cctccttccg caacgtcgct ccggcatcgg gctacctcgt cggagggacc
    11401 ggcctcgtcc ggttggcgga cgtctcgatc ctggacgagc cctccgtcgt gccgacctcg
    11461 gttctcgtcc accgcgccgc gaaccggctc gtcgatggag ccttcgatct gggcacggtc
    11521 gcggacgcgt acctggacac tccggacgcc acctctcgga gtgcgagccc gtcggccacg
    11581 ctcgccgtcg cgtcagggcg gctcctggtc cggaagacag gcaccggaca gacgagtctc
    11641 tcgttcgatg tgctcagcag acccgggcag gtctacgccg ccgacctcgt catcggacag
    11701 gccgctgcga acgggtcgat gatcgtctcg gagtccttcg tcaccgtctc cggtcgtgac
    11761 gcccgcggca tccctgtcac cgtccgctcg gagcccgtct cctcgacgac gcagtcgatg
    11821 gcggcgatgg ccgcggcact cccgttccgg gtaagacccg cgaccggcgt ggatcgccag
    11881 gcgccgtcct gggcgtcgca tttccgcgtg accgtcggcc tgaacgaccc cgccgcggga
    11941 acggtcggca tcgacgacgc ggtcgtcacc gagatgtgag gaccggccgc tcgcgcggtg
    12001 gcccgatgcg tcagtgggcg ccgcctccgg gggcgacgac ggcctgcacg gttctcgcga
    12061 gcagcgcgag gtccccggtg aacgaccagt tctccacgta gtagagatcc agtcggatgg
    12121 cgtcctccca ggagagcgtc gaccgcccgc tgacctgcca gagcccggtc atgcccggct
    12181 tgacgttgag gcgccggcgc gcggcttcgt cgtagagctc gacttctccc gccacctgcg
    12241 gccgcggccc gacgagcgac atgtcgcctc tcagcacgtt gaagagctga gggacctcgt
    12301 cgatcgagta cttgcgcatg aagcgtccga tcggtgtgat gcgagggtcg tcggtgatct
    12361 tgaacagtgg tgttccggac gttccctgag cggcgagcag ctcggcgagc tgatcatgag
    12421 cgttcaccac catcgagcgg aacttgatca tgccgaaggg cttgccgttg atgccgatcc
    12481 gcgtctggcg atagaacagg ggccccgagc tcgtcagctt gacggccagt gcgaccgagg
    12541 cgatgagagg catcagcacg gcgatgaggc tcagcgatcc gacgatgtcg agggcacgct
    12601 tgcgcgcctg cttgctgccc tcgaatcgag gtgtctcgat gtgcacgaga ggaaggcccg
    12661 ccaccgggcg catgtggatc ctcggtccgc tgatgtcggt gaggctcggc gccatgacca
    12721 ggtgctggcg cctcggctcg agactccagc tcaactgtcg gatctgctcg ggtggcaggt
    12781 ggtcgctgct cgtgatgatg acggtatcgg cgccggtccg gttcaggatg cccggcaccg
    12841 catccaccgt gatgttctcg aagacaggca ccccccaccc gctcacccga tcgctggcca
    12901 gatcctcggg gatgcacacg ccgacaacga gatacccggc cccgggggcg cggacgagct
    12961 cgcggtagat gtgctcgacg ctccgtggcg agccgacgag gacgacggag gaggagtacc
    13021 ggcccgcgct ccgctgctgc cgcagccaca ccctccaggc tccgcgtccg agccagagca
    13081 ggacgaggcc gagcgggagc gcggtgatga tgtacccgcg ggcgaagccg atctggccga
    13141 ggtaggcgac gcacgtgatc acggcgaaca gcaggagcgt cgcatcgagg atgcgcttgt
    13201 actccgtcac ctctccgccg aggacacggt cttcgcgtgt ggcgtagaac ttcaacaggg
    13261 cggcccacag caccacgatc atcgaggaga cgatccagta gttcgcgagc aggcccgcga
    13321 tctccggctg atggccggcc acgaacaatt ctcggctctc cactccgaac cagaagaact
    13381 gactgctgaa gaccgagaac acgatgacga ggacatcggt gatgacgagt tttctggcca
    13441 ctgctcggga ccaggagctc cggcccttct cggaggaaga gctcttcgtg gaagtgggtg
    13501 tttgcagttt caccgtgtga gccctgtctg cgactgaccg ctgttctctc gcataagcga
    13561 cctgccctca gcgtagtggt cgggcgtcgt gctcctccgt cctgagcgaa gctccgcgca
    13621 aaggcccctc ctaggggatg ctctcggcta ttccgactat tccccgacga tgaggacgcg
    13681 ctcggacctc cgttgtgcgc cgtcgacgac cgctcggacg tcggcggcgg agatgtcccg
    13741 agcacgggga gtcgaggtgg ttcggcgggt cggatccgtc gggcggttca ggtctctcgg
    13801 ctcgcgcggt cggcgctcgt gcgtccggtg ctgatgcggt gtcgcggcgt cccgccgctg
    13861 tcgatggggc gtgacgcgca acggcaggag aagactcggg agaggcgccg cgagagctcg
    13921 cgaggggaga ccggcggacg atcgtcgggc accgacggcg ggcacgtcgt cgccggcagg
    13981 gacgagcagg acgcttccgc tgccggaaac gacgacggca cactcgtgct catcgagacg
    14041 gacaggtgct gcgccggagt gctcctgggc gtggagccga gatcggcgca tgcgtctgcg
    14101 gtcatcggct ccggccgcgg ccgcggccag gcgcccgtgg tcgggcgctc cgggggcgag
    14161 cgcctcgccg gcggacgatc ctgcctcgac ggggagctgc tcggagccga tgacgagccg
    14221 tgtcgcggct tcccggggcg cttccgctct ccgttcagga cgtcgcggat cgctcgggtc
    14281 gtgtcgggtt cgggccggtg agcgcgaccg gggatcgagg ccctgtcccc gtccgcccga
    14341 gccggtcgtc ctgtgagcga ggcatccgct cgcacgagcg ggtccggtga cgtcctccct
    14401 cggtgatcga ggggaggacg tcaccggacc cgctagtcct gctcgggggg cgcgccgtcg
    14461 tcagggcgcc ccctggtgat cagctcagcc gcagagtgcc gcgcctgcca cgtagaacgc
    14521 gcggatgccg atgttcggcg tcgaggccga cgccacgctg gtgacgttcg tgatcgtgac
    14581 gacggggctg ccggtgctgt tgctgtccca cgtcccgggg ttgctcaacg gggtgcggta
    14641 gtactggttg ttgtcaccga tcacgttgat ccagttgccg ccgatctcga ctccgaggtc
    14701 cttcgccgtg cgtccggccg gaagtgcggt gagctgggtg ccgtcctggt cgaacacagc
    14761 ggccgtcgtc gcgaagatgc gacgcgtcgc gccgaagacc tgggtgtcgg cggcgacctg
    14821 acgcagcccg gtgactgtgg cgaggacctg cgtccacggc gaccaagacg ctccggcctc
    14881 gatggtcttc gtcgcctccc atgccgtccc gtcggtcgcg acgagcgaca cccgccacag
    14941 gctgtcgtcg ctgaacgaca cggcgatgtc gaggacagtg cggcctccgg gcgcggccgc
    15001 gagcgcgacg ccgtcccagt cgtacaccgt gctgccgctg gccgagaaca ggcgggctcc
    15061 gcggtcgccg ccggcgatga tcagaccgtc atccgccgcg atgctggtca tgccgatgcg
    15121 gatgggggtc gtcgtgtccc actcgtagaa gccgccggag ggggcggtgt gcgagtagac
    15181 gtcgccgtcc tgggagacga cgtagctcag gtaggtcgca gacgcagccg tgtcaccgac
    15241 gccggtccac gcgactgcga aatcgaccac agtggtgaca gcttccggca tctcggactc
    15301 gacattgttg cgacgtccgc ggaaggtcga ggtgcgggtg ccgctggtgc cgttcacgat
    15361 cgctgcggtg gtcgcatcgg ccacgggaac ggtcggctgg gccggattca ccacgcctgc
    15421 tgtcgtggcc gtgatggtgc ccgtctggct gactccggcg gtggcgaaac gcagaccgtt
    15481 gaagccctcc aggaggaggc ttccgccggc acccgtgaac agcgtgcgag gtgtggccgt
    15541 gccgtcgtac cagcgcagcg cggtcggcag agtcaccgtc accgcgatgc ctgcggcggc
    15601 cggaactccg gaatcgctca cctggaggta ggcgttgaac gggttgcagc tgctcgtcgt
    15661 gtaggaagta gtggcatcgc caccctcctg gtcgacgaaa gcgaccgtgc gcacggtcac
    15721 cggggccgat gcggcggcga gcggcgcacc gatcgccgcg acgacgacgg gagtggtcca
    15781 tgcggccgcc tgcaggacgg tccggcggcc gggaaccgca ttgcgagccg gaacgggcga
    15841 atcagaaggg gacgtgttcg acataatatg cctctctggt tggacgaatg gcctgcggat
    15901 cttcaacgaa cgacctgagc cgtagacggc agacgttccc tcggaagatc cactgctcat
    15961 gtcgcagcgt cccgagagtt tttccgcgac gattgatttc gcgagagggc tgtccttccc
    16021 gcggcaggcc tgagactact gcacaccaag taattccacg caacggggtt cgacgatctc
    16081 gagacagatg agagaggctc cgaaacggcg gcggaacgac tatccgcctc actccgaggt
    16141 cgccctgttc tgccgcaaga gagatgattg atcgacaggt gaggcgcaga gccgtctccc
    16201 gcttgtgttc cttctctctc ctggcggatc gatcgggccg tgagtccggc cggatgaggc
    16261 gctccggtgt cggctgcccg gatgcgtctc cccgctcgct ttcccgcccg aggaacccct
    16321 acaaggccga tcggaggatg gcctctacgg ccttcgtgat tccgtcacca ggcgcgcacg
    16381 ggcaggaccg cctcccgagg gcgtcctcct cgttcaggtg cagcgtctcc gtcggctgca
    16441 cggcctcgtc gtgatccgac tgatcggcct cacctcggcc gggcgcgggc tcgttcgcgg
    16501 atccccggcg gcgagaggag gatcgccggc gcatccgcag tcgctcatcg acccatcagg
    16561 acgtccgctc cgttccggct cctccgacgc tgccgtcgcg tcgtccgacc tcggcgccgg
    16621 agcggcggcg acgggcgccg ctccgatggg actcgggtcg ggtccggtga gcgggcgcgt
    16681 tccgcctccg gcgcagtcgg gtgcgggagg atgatcggat ggacgacacg gcggtacggc
    16741 ggctcctcga ggggctcgcg ggggcggagg cgagcttccc gttcggcccg ggcacgcggg
    16801 tgtggaaggt cgccgggaag gtcttcgcgc tcgagtcgga gcgcttcgag cgccccgtcg
    16861 tgagcgtcaa ggcgctgccc gagaacgtgg tgcacctcgt cgcgggggtc gagggcatcg
    16921 agcccgggta ccacctgaac aagaagcact gggtgaccgt cgatgcgggc ggggcggtgg
    16981 agtccgggct ggtgctggag ctgatcgagg agtcccacgc gatcgtcgtc gccggactgc
    17041 ccaagcggct ccggctcgcc ctcggcggca ccgccgccgg ctcgctgaac gaggaccgct
    17101 gaacgacgcc cgcccggcgc cgccctgccg cagcgccccc gccgcggcag aggctcgcgg
    17161 ggcgcggcct acaggccgta ggagcggagg tacgcggcgg tgtcgtgcca gccctcgacg
    17221 gcgaagcact cgacgcccat cgccttgacg gggtagtcgt tgccgtccgg gtcgaggcgg
    17281 tcgccgacga agatcatgtc gtcgagaggg atgcccgtca gctcggtgag cttgttcatc
    17341 ccgtacgcct tgtcgatgcc cttgcgggtg atgtcgaccg acgtcgagcc gccggagcgg
    17401 acctcgaggt cggggagcac ggcctgcacg gcctcgcgga gggtgttctt cttctcgccg
    17461 tccgggtccc aggcctgctt gacctcgacg ggcgcggact ggccgagggc cgagaaggtg
    17521 atctgcgagt cgcggtcctc gaggatcggg ccccaggtct cggactccca gtagccgagc
    17581 tccttcgcct tctcctcgac ggcggcgagc gcgcgcgact tctcgtcctc ggtgaggttc
    17641 tcggcgtaga tctgcgccca gtcgccgttc tcgtaccggt agtactgcgt gccgcaggtg
    17701 ggcatgaggt gcagcttcgc gagcacctcg gggtcggcgc cctcgaggcg gtcgagcacc
    17761 tgcatccgga actggccgat ctggccgccc gagatgatgc acacctcggt ggcctggagc
    17821 agcttcacga agaggtcggc catcgccggg tcgacggggg acttcgaggc ggcgagggtg
    17881 tcgtcgaggt cgaaggccat caggcggggc agggtgctca tggaactcgt ttcacggtct
    17941 gcggacgggg cggtaacgag gatacggggc gccgccgcaa cgcgcgcgcg gtcggcgcga
    18001 gcgggctccg agcgcagact gggggcatga ccgccgccac agcgcccgac ggaggacgcc
    18061 gctccgttcc gcgcactctc gcccgcatcc tcctgggcct ggtgctcgtc acggccggct
    18121 cggcgcacct gacggtcgcg cgtcaggcct tccaggcgca ggtcccgccg tggctgccgg
    18181 ccgacccgga cctggtggtc gtcgcgtcgg gcgtcgtcga gatcgcgctc gggctggcgc
    18241 tcgtcgtgct cgtgcggtgg cgcgtgatcg tgggagtcgt ggtggccgcg ttcttcgtcg
    18301 cggtcttccc ggggaacatc tcgcagctgg tgacgcggac gccggcgttc ggcctcgaga
    18361 cggacgcggc gcgcgcggtg cggctcgtct tccagcccct gctggtggtc tgggcgctct
    18421 ggtcgaccgg ggcgttctcg gcctggcggg cccgccggtc gcgacgccgc ggggactgag
    18481 ccgccggtcc gcggcccgat cgtcccgcga tcctccggaa cgacgaacgg cggtcggcgg
    18541 gagaccccgc cgaccgccgc ccgtgccctg ctcggctagg ccgcgaggcg gcgtcgcgcg
    18601 acgaccagcg cgagacccga cagcagcagc acgagggctc cgccgatcag gccggccgcg
    18661 tcggcgccgg tgttcgcgag cgagcccggg ccggagcctc ccgcgacggg ggccgccgtg
    18721 gtggtggggt gcggcgacgg agcggtggtg ggctgctccg tcggggtgcc gggctcggtc
    18781 ggcgccgggg tgaccgggac ctcggcggcg ggctccgtcg tcagcgacca gttggggtcg
    18841 tagaagtcgg cctggtcgat cacgccgcgg gcggtcgacc agtcgatgag gagctggcgg
    18901 atctcgagac gctcgtcgta gacgagcggt gcctgcgcga cggccgggta ggcgcctccg
    18961 ccgctctggc ggtagttgtt gaccgccatc acgaagcgct cgtcgtcggc gaccggggtg
    19021 ccgtcggcgt gggcgagacc gcggatccgc gagccggcgg gctgggagac gtcgatcacg
    19081 tagtccaggc ccgagatcgc gtcgtagttg tagtccggga tgccgtcggg gcggtcctcg
    19141 gtcgtcgcgt tggtgccggt ctcggggtcg aacacggcgc cctcggcggt ctgcacgaag
    19201 tagcgggccg agaactcgag gtagtcgcgc acctcggctc cggtcagctc cactccgcgg
    19261 agggtgttct cgtagatgta caggcccgcg atgtcgcgga tgctgacctg ccccttcggg
    19321 aagacggcgg tgcgcgagaa cggcgacgcc tgcgagatca ccggcaggtc ggcccactcg
    19381 gtgccctcga gagccgtctc gacggtctcg gcctggacgg tgttgatgaa gtcgatgatc
    19441 ggggtgtcct cgtagcgcga ggtcgcggcc gagagctcct cgaccgagtc ggcgacgggg
    19501 gtgttcacgt actcgatcgt ggcggcgtgc tgctcggcga gggcgtcgac cagtgcgggc
    19561 gactcctcgg cgatgtcctt cgcgtagacg ggctgcgtga cgggcgcgtt cccggccgac
    19621 cagtcgacct cgaggccgcc cgcggcgtcc ggcaccaggt tcagggtgac ctcggtgagg
    19681 ccctgcgccc agaactcggg ctgggtgacc agcacctgct cgccggcgac gttggtgaac
    19741 agcgtctgcg gcaggtcctt gtggctgtgg ccggcgacga ccacgtcgat gccggggacc
    19801 tgcgtcgcga tgttgttgac gacgtcctcg ttgaggtcgg cggggtcgta ctcggcgtcc
    19861 ggcaccgtgc cctggccggt gtgcgcgagg acgacgacca cgtccgcctg ctcctgcacg
    19921 atcgggaccc actgcttcgc ggcggcgacc atgtcctgga actcgaggac gccgtcgacg
    19981 tactgcttgt cccagacgcg gacgccgggg gtgacgaggc cgaggacgcc gacggtgacc
    20041 gtcttcccgt cgatctcgcg ctcgatcagc gtgtaggggt cgtggtacgg cttgccggtg
    20101 gcgacgtcga cgacgttcgc gcccagcagc ggggcgttca ggtcgccctc gtacgcgctg
    20161 agcatgtcga gcccgtagtt gtactcgtgg ttgccgacga cctgcgcgtc gtagccgatg
    20221 gtgttgaacg cggtggccat cgggtgcgtc gtctcgccgg agaggacgcc cgcggcgccg
    20281 tcgccgaggc cgtagtagta ggtgagcgg
//
