LOCUS       NZ_PSVY01000001        21101 bp    DNA     linear   CON 18-SEP-2024
DEFINITION  Rathayibacter sp. AY1D1 AY1D1_1, whole genome shotgun sequence.
ACCESSION   NZ_PSVY01000001
VERSION     NZ_PSVY01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Rathayibacter sp. AY1D1
  ORGANISM  Rathayibacter sp. AY1D1
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Microbacteriaceae; Rathayibacter.
REFERENCE   1  (bases 1 to 358798)
  AUTHORS   Davis,E.W. II, Tabima,J.F., Weisberg,A.J., Lopes,L.D., Wiseman,M.S.,
            Wiseman,M.S., Pupko,T., Belcher,M.S., Sechler,A.J., Tancos,M.A.,
            Schroeder,B.K., Murray,T.D., Luster,D.G., Schneider,W.L., Rogers,E.,
            Andreote,F.D., Grunwald,N.J., Putnam,M.L. and Chang,J.H.
  TITLE     Bacteriophage NCPPB3778 and a type I-E CRISPR drive the evolution of
            the US Biological Select Agent, Rathayibacter toxicus
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 358798)
  AUTHORS   Davis,E.W. II, Tabima,J.F., Weisberg,A.J., Lopes,L.D., Wiseman,M.S.,
            Wiseman,M.S., Pupko,T., Belcher,M.S., Sechler,A.J., Tancos,M.A.,
            Schroeder,B.K., Murray,T.D., Luster,D.G., Schneider,W.L., Rogers,E.,
            Andreote,F.D., Grunwald,N.J., Putnam,M.L. and Chang,J.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2018) Botany & Plant Pathology, Oregon State
            University, 2082 Cordley Hall, Corvallis, OR 97331, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-NOV-2017
            Assembly Method                   :: SPAdes v. 3.11.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 161.699x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002932635.1-RS_2024_09_18
            Annotation Date                   :: 09/18/2024 02:01:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,548
            CDSs (total)                      :: 3,497
            Genes (coding)                    :: 3,463
            CDSs (with protein)               :: 3,463
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 34
            CDSs (without protein)            :: 34
            Pseudo Genes (ambiguous residues) :: 0 of 34
            Pseudo Genes (frameshifted)       :: 6 of 34
            Pseudo Genes (incomplete)         :: 27 of 34
            Pseudo Genes (internal stop)      :: 3 of 34
            Pseudo Genes (multiple problems)  :: 2 of 34
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:54:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 84787
            Orig. end                         :: 105888
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PSVY01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21101
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21101
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21101
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11101](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11101)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(4..17)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.06"
                     /tool="antismash"
     misc_feature    complement(684..699)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.68"
                     /tool="antismash"
     gene            1171..1662
                     /gene="def"
                     /locus_tag="C5C56_RS00410"
                     /old_locus_tag="C5C56_00410"
     CDS             1171..1662
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012298732.1"
                     /locus_tag="C5C56_RS00410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00410"
                     /product="peptide deformylase"
                     /protein_id="WP_104273474.1"
                     /transl_table=11
                     /translation="MTERQIRIFGDPVLKTRSTTIETVDVGVRGLVEDLVDSVRPPGRA
                     GVAAPQIGVNLRAFSYNVDGVIGYILNPEIIELSGDPRPVDEGCLSVPNLWYPAIRYPH
                     AKVRGTDLDGNEIVLEGDGLMAQALQHECDHLDGRLYLDRLSQDDRRAAMKAVRESDWF
                     "
     gene            complement(2207..4030)
                     /locus_tag="C5C56_RS00415"
                     /old_locus_tag="C5C56_00415"
     CDS             complement(2207..4030)
                     /NRPS_PKS="Domain: AMP-binding (23-465). E-value: 2.6e-89.
                     Score: 291.6. Matches aSDomain:
                     nrpspksdomains_C5C56_RS00415_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010202316.1"
                     /locus_tag="C5C56_RS00415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00415"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_104247148.1"
                     /sec_met_domain="AMP-binding (E-value: 3.2e-84, bitscore:
                     277.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQFDSPLVVPADPQANTTALLLDRVRETPDRPLFALPDGDGWRD
                     VTAQEFLDQVTALAKGFVAAGLEPGEKVGLICKTRYEWTLIDFAVWFAGGILVPVYETS
                     SPAQVQWNLADSGAHAVIVETPEHFARFDEIRADLPEVRLAWQIGLGDLDKLVARGVDV
                     PDAEIERRRSLATGTDIATIIYTSGSTGRPKGCIIRHSNFVELSRNSAVALTELIHQPG
                     ASTLLFITTAHVFARFIAILCVHGGVKVGHQADTRQLLPSLASFKPTFLLAVPRVFEKV
                     YNSAEQKAEAGGKGKIFRRAADVAVAHSMALEAGSVPLALKLQFLLFDRLVYSKLRTAM
                     GGNVRFAVSGSAPLGDRLGHFFHSLGIKILEGYGLTETTAPATVNRTERFKIGSVGPAM
                     PGVSIRIAGDGEIQVRGIDVFGGYWNNEAATAESFDGEWFRTGDLGTLDEDGYLRVTGR
                     KKEIIVTAGGKNVAPAALEDPIRANPLVGQVVVVGDQRPFIAALVTLDSEMLPTWLANN
                     GQDKGLSLEDAAVNPVVLAEVQRAVDAANERVSRAESIRKFVILPTEFTEASGHLTPKM
                     SIKRNVILADFADTIAAVYSAAPATEGISLR"
     aSDomain        complement(2636..3961)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C5C56_RS00415_AMP-binding.1"
                     /evalue="2.60E-89"
                     /label="C5C56_RS00415_AMP-binding.1"
                     /locus_tag="C5C56_RS00415"
                     /protein_end="465"
                     /protein_start="23"
                     /score="291.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DRVRETPDRPLFALPDGDGWRDVTAQEFLDQVTALAKGFVAAGLE
                     PGEKVGLICKTRYEWTLIDFAVWFAGGILVPVYETSSPAQVQWNLADSGAHAVIVETPE
                     HFARFDEIRADLPEVRLAWQIGLGDLDKLVARGVDVPDAEIERRRSLATGTDIATIIYT
                     SGSTGRPKGCIIRHSNFVELSRNSAVALTELIHQPGASTLLFITTAHVFARFIAILCVH
                     GGVKVGHQADTRQLLPSLASFKPTFLLAVPRVFEKVYNSAEQKAEAGGKGKIFRRAADV
                     AVAHSMALEAGSVPLALKLQFLLFDRLVYSKLRTAMGGNVRFAVSGSAPLGDRLGHFFH
                     SLGIKILEGYGLTETTAPATVNRTERFKIGSVGPAMPGVSIRIAGDGEIQVRGIDVFGG
                     YWNNEAATAESFDGEWFRTGDLGTLDEDGYLRVTGRKKEIIVT"
     CDS_motif       complement(2729..2803)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C5C56_RS00415_0002"
                     /evalue="2.30E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="C5C56_RS00415"
                     /protein_end="434"
                     /protein_start="409"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GEIQVRGIDVFGGYWNNEAATAESF"
     CDS_motif       complement(3431..3490)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C5C56_RS00415_0001"
                     /evalue="1.70E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="C5C56_RS00415"
                     /protein_end="200"
                     /protein_start="180"
                     /score="26.6"
                     /tool="antismash"
                     /translation="ATIIYTSGSTGRPKGCIIRH"
     misc_feature    4053..4067
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.28"
                     /tool="antismash"
     gene            4266..5225
                     /locus_tag="C5C56_RS00420"
                     /old_locus_tag="C5C56_00420"
     CDS             4266..5225
                     /EC_number="2.7.1.2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020077359.1"
                     /locus_tag="C5C56_RS00420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00420"
                     /product="ROK family glucokinase"
                     /protein_id="WP_104222580.1"
                     /transl_table=11
                     /translation="MHAIGIDIGGTKIAGALVDEFGGILREDRRPTPAGHPELIVDVVV
                     EMVEHLRSGLLPGDVSAVGVAAAGFIDASQSIVYYAPNINWRNEPFREKLSARIDLPII
                     IENDANAAGWAEFRYGSGRLVSDMLMLTIGTGVGGAIVINDRLLRGGFGAAAEIGHMRV
                     VPGGLPCGCGARGCIEQYGSGRALQRFAGELADAGGIGQGIADARARNGGELNGHLISE
                     LITAGDLGALAALRQLGHWLGEAAASLSAVLDPQMFVIGGGVAQAGDLLLDPIRQAYLD
                     NLPARGYHPEPEFRIAELVNDAGVVGAADLARLHASSL"
     gene            5269..5958
                     /locus_tag="C5C56_RS00425"
                     /old_locus_tag="C5C56_00425"
     CDS             5269..5958
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015490538.1"
                     /locus_tag="C5C56_RS00425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00425"
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_104222581.1"
                     /transl_table=11
                     /translation="MFYWFMKHIVAGPLLKTIFRPWVVGADKVPQNGGVILASNHLSFI
                     DSVILPLVIERNMVFLAKSDYFTGKGLKGWATRTFFTATGMLPIDRSGGKASEASLNTG
                     LRVLAGGHALGIYPEGTRSPDGRMYRGRTGVARMVLEARVPVIPVAMIDTARIMPIGKR
                     LPKLGRIGIVFGEPLDFSRFEGMEGDRFILRSITDEIMYELLALSGQEYLDVYATSVKE
                     KRAALTR"
     misc_feature    complement(5312..5326)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            6136..7470
                     /locus_tag="C5C56_RS00430"
                     /old_locus_tag="C5C56_00430"
     CDS             6136..7470
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005049099.1"
                     /locus_tag="C5C56_RS00430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00430"
                     /product="class II 3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_104222617.1"
                     /transl_table=11
                     /translation="MVAGLDYWRELEIKQQPQWPDAEAVRAASAEVAALPPLVFAGEVD
                     QLRERLGAAARGEAFLLQGGDCAETFAGATAEQIRNRVKTVLQMAVVLTYGASMPVIKM
                     GRMAGQFAKPRSSDLETRGDVTLPAYRGDIVNGYDFTPESRAADPRRIVQGYHTAASTL
                     NLIRAFTQGGFADLRLVHYWNKGFTENPQNQRYEQLAREIDRAVKFMVACGADFEGMKR
                     TEFYTGHEGLLMDYERPMTRIDSRTGTPYNTSSHFIWIGERTRELDGAHVDFLSRVRNP
                     IGVKLGPSTTPETMLELIDKLDPEREPGRLTFITRMGAGRIRDALPPLLEAVKRSDALP
                     LWVTDPMHGNGLTTPTGYKTRRFDDVVDEVKGFFEAHRAAGTHPGGIHVELTGDDVTEC
                     LGGSEHIDEATLATRYESVCDPRLNHMQSLELAFLVAEELRGRAI"
     gene            complement(7521..9491)
                     /gene="pknB"
                     /locus_tag="C5C56_RS00435"
                     /old_locus_tag="C5C56_00435"
     CDS             complement(7521..9491)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019181592.1"
                     /locus_tag="C5C56_RS00435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00435"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_104318955.1"
                     /sec_met_domain="Pkinase (E-value: 6.1e-60, bitscore:
                     197.1, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSQLDPLLGRLVDGRYEVRSRIARGGMATVYLAHDQRLERRVA
                     MKVMHGHLSDDATFKNRFVQEARSAARLAHPNVVSVFDQGQDSDMAYLVMEYLPGITLR
                     DLLKERGRLTAQQVVDIMHSVLSGLAAAHRAGILHRDLKPENVLLADDGRIKIGDFGLA
                     RAASANTASGQALLGTIAYLSPELVTRGTADTRSDIYAIGIMIYEMLTGEQPFTGEQPM
                     QIAYQHANDSVPYPSATVASVPTSLDELVLWATERDPDMRPRDAGVMLAQLLEAERLMD
                     ITPSDRRGDTQAVTPLPAPVADPAPATAVFDTAEPGQTSVFDPAPAPGAVLVVDEDDDT
                     VARLASRRRVRRRRGVLLTVVVLLLALIGGGTAWWFGEGPGAIVSIPDVVSQSQQDATA
                     QLQAQGFEVQPQETPDLTVPAGTVVSSDPPGGQGVHKGSVITLTVSSGPRQLPVPSLAG
                     LSEADAAAAVTGGSFTVGDVSKIFDADVDAGVVVSASLPDGSALPETMSETSTIAMVVS
                     LGPIPNVVGLSIDDATAKAEAAGLALDRSGEDWSDTVAAGVVLTQANPEAPAVTGDTVS
                     VVVSKGPEPVAVPNVVGMNRDEAKAALEAADLSWSYSLTTLGPLIDAAPNELTKVTNQS
                     NKAGDLVQRGTTIQLSITITT"
     misc_feature    9619..9634
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.66"
                     /tool="antismash"
     gene            9619..9984
                     /locus_tag="C5C56_RS00440"
                     /old_locus_tag="C5C56_00440"
     CDS             9619..9984
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017886613.1"
                     /locus_tag="C5C56_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00440"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_104222583.1"
                     /transl_table=11
                     /translation="MTDSSASPATSTDSELEWLTVPDLVELTGLGAGRVRRLLEERHLL
                     GTRRDGVLKVPALFLRDGEPMSEIRGTAILLADSGFTDDEAVDWMLTVEESLGTSPIVA
                     LRAGRKAEVRRVAQALA"
     gene            complement(10001..11101)
                     /locus_tag="C5C56_RS00445"
                     /old_locus_tag="C5C56_00445"
     CDS             complement(10001..11101)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038557.1"
                     /locus_tag="C5C56_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00445"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_104222584.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.2e-45, bitscore:
                     149.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHSSRLVDRVQLRIDEFLTGRTPILRSIGEDVSALGDLSRDFLS
                     GGKRFRARFCEAGWNAVSSTSSEAHPSGSDPIARVGAGLELFHAAALVHDDVIDNSDTR
                     RGAPAAHRRFSSFHADGGWTGDRDEFGRSSAILLGDLLLVWSDEIFAAAEWSLGDRVAA
                     ERARAEFNLMRTEVTLGQYLDILEESAWVQHPEHEHLQRAERVVVYKSAKYSIEAPLVI
                     GGSLAGGDDAQLDALRRFGLPVGIAFQLRDDVLGVFGDPAVTGKPAGDDLREGKRTVLL
                     GLARGACSPGERAELDAVVGRSDADAASIARAQEIIAGSGALERLEERIDQEVAAAIAV
                     LPDAPLRTEGVAELRELAAQVTVRTS"
     gene            11247..11636
                     /locus_tag="C5C56_RS00450"
                     /old_locus_tag="C5C56_00450"
     CDS             11247..11636
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011186332.1"
                     /locus_tag="C5C56_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00450"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_104318956.1"
                     /transl_table=11
                     /translation="MPLSEHEQRLLDEMERNLYQNDADFVAAVGKGRGGTNYRALVLGI
                     LLGILGLAVLVAGVVVRQPLVGILGFAFMLGGVIVAMRPAAGGSSAPGLPDVGRPSKPR
                     SGNRQGSGFMDRLNDRWDNRGDGRG"
     gene            11877..12308
                     /gene="mraZ"
                     /locus_tag="C5C56_RS00455"
                     /old_locus_tag="C5C56_00455"
     CDS             11877..12308
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="mraZ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011186331.1"
                     /locus_tag="C5C56_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00455"
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="WP_104222586.1"
                     /transl_table=11
                     /translation="MFLGTYSPKLDEKGRVILPAKFRDELSSGVVVTRGQERCLYVFSQ
                     AEFEVMHEKIRQAPVTSKQARDFLRVFLSGASAETPDKQNRVTLPAPLRAYAGLDRDLT
                     VIGAGNRAEIWAQGAWETYLQEQESVFSDTQEEVIPGLF"
     gene            12418..13401
                     /gene="rsmH"
                     /locus_tag="C5C56_RS00460"
                     /old_locus_tag="C5C56_00460"
     CDS             12418..13401
                     /EC_number="2.1.1.199"
                     /GO_function="GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011774408.1"
                     /locus_tag="C5C56_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00460"
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="WP_104225374.1"
                     /transl_table=11
                     /translation="MAENTPKGAPRPTEERHLPVLLERCVELLAPALERDGAVVVDATL
                     GMGGHSLALLERFPGLHLVGLDRDPEALQLAGERLSAHASRIDLVHAVYDELPDVLDEL
                     GIDTIDGALFDLGVSSLQLDETERGFSYSKDAPLDMRMDSTAPLTAASILADYDETALR
                     RIFHEYGEERLAARYAKKIVEARREAPLERSGRLVEIIQAATPVAIQRNGHPAKRVFQA
                     LRIEVNQELSVLERAIPAALGRINEGGRIVVEAYQSLEDRIVKRALQAASSSTAPAGLP
                     MELPEHRPEFRLVIRGAELASDDEKARNPRATPVRLRAAERIRSTA"
     gene            13398..13958
                     /locus_tag="C5C56_RS00465"
                     /old_locus_tag="C5C56_00465"
     CDS             13398..13958
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C5C56_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C5C56_00465"
                     /product="hypothetical protein"
                     /protein_id="WP_104222588.1"
                     /transl_table=11
                     /translation="MSATAVIDPAVIDTARRARPEEEAPRPRIEAVPAGQAQSRPKLVY
                     GIVAVAGLFAIIVVQLLVSVGLSQGAYQISALQTEQKSLTRSNAEKQDAVDTLSSPQNL
                     ATAAQGLGMVANTAPVYLRLSDGAVLGDPSSAASSEVAGTASAPLVPNALVPALQPGAS
                     ASSPAVDGAAVPLQGELPAPITH"
     gene            14074..15846
                     /locus_tag="C5C56_RS00470"
                     /old_locus_tag="C5C56_00470"
     CDS             14074..15846
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015490529.1"
                     /locus_tag="C5C56_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00470"
                     /product="penicillin-binding protein 2"
                     /protein_id="WP_244229623.1"
                     /transl_table=11
                     /translation="MRHHRSSRRRTAVTFVIIVAVVGLFIGKLVDIQIVRANELTDAAA
                     QNQSNSVVTYGQRGPIVDRSGTVLADTTTRYRLTTSPKNVAEFPRELGEDQKVMVSVQQ
                     AASEIGAITGQSVEQITGAVDAALAKDAKANYLILSEGLDLEAYQKLVALDIPWTYFET
                     QQGRSYPNGAVAGNLVGYVGADGAAQEGMEYAENTCLAGQNGSESYERSADYVRIPGST
                     VSETPAVDGGTLKLTIDSDLQYYSQQVLSQRVAEVGGSYGIVVVQEVKTGKLLAVAETP
                     TVDPNNVEASASADRSSRAFRAPFEPGSTFKPMTAAMLIDQGQAGPTTQVVVPDSFEKD
                     GASFSDDFAHTPTNYTLTGILKDSSNVGISMLGSRLSAQTRYDYLQKFGLGTPTTSGFP
                     GEEGGLLADYQDWDNQTNYTTMFGQGVSATAVQVASIYQTLGNGGVRLPSQLIDGCTTA
                     DGSVVDVPDATGTQVVSSSAAKQVVDMLQTHYNEGWLANDIHVDGYNIATKTGTAQQPD
                     GKGGYSKSYTVSLAGLAPAEDPEYVVTVTIADPVKMNTSQATAPVFQQVMTQVLKTNRV
                     EPSTVPPVEYPTTW"
     gene            15897..17459
                     /locus_tag="C5C56_RS00475"
                     /old_locus_tag="C5C56_00475"
     CDS             15897..17459
                     /EC_number="6.3.2.13"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008765 -
                     UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate
                     ligase activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018191370.1"
                     /locus_tag="C5C56_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00475"
                     /product="Mur ligase family protein"
                     /protein_id="WP_104318957.1"
                     /transl_table=11
                     /translation="MHDPRPQSSLRPEHPVPRSLSQLVAEFSLGPVRGLEGVEVSGVTL
                     DSNQVESGDLYVGVAGRRAHGAAFASAAAASGAVAVLTDPAGAELAADSGLPVLVTPDP
                     RAALGDVAAWIHRTREDVPTLFGVTGTNGKTSVVYILDALLRRLGVVSGLSSTAERRIG
                     DVAVVSSLTTPEASELHGLLARMRESAVRAVSIEVSAQALTRHRIDGLVFDVVGFTNLS
                     HDHLDDYSDLREYFEAKADLFEPERARRGVVTVDSAWGRELAERSRIPVATLAGSPVVG
                     VAPTTPADWSMTVLDATPDSTTFRLEGPENRSVVVTVSLIGWYMASNAALAIVMLVESG
                     FDLDAVAHALEDSRLDVYIPGRAELVSGERGPRVYVDYGHTPDAFQNALEALRTITPGR
                     LFMVFGADGDRDTTKRSDMGGIAARLADVVVVTDFHPRWEDPAAIRAALLQGARAAVPD
                     REIHEIADPRAAVRAAVALAREGDSILYAGPGHEDHQEIAGVHMPYSARDDVRHALREA
                     GWL"
     gene            17460..18884
                     /gene="murF"
                     /locus_tag="C5C56_RS00480"
                     /old_locus_tag="C5C56_00480"
     CDS             17460..18884
                     /EC_number="6.3.2.10"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="murF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017794464.1"
                     /locus_tag="C5C56_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00480"
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="WP_104247145.1"
                     /transl_table=11
                     /translation="MIALTLTEIAEAVSGRLHLAGSSATAATVIDGATETDSREIAPGG
                     IFVAKRGEHTDGHLFAPAALERGAALLIVERPLDLDVPQVLVDDSVEALGALATEVVRR
                     VRAKGGLTVIGVTGSNGKTTTKNLLRTVLERVGETVAPRGSFNNEVGAPITMLQVSEST
                     RFLVAEMGASAVGEIRRLVRMARPDVGVVLAVGLAHAGEFGGIERTLEAKTEMVADLTA
                     DDVAVLNADDGRVASMAGRTAARVLWFGRGESADVRAVDIDATADGTRFAIEVSAGEGR
                     EAARAELLLRVLGEHHVMNALAATAAALSVGVALPAIVEALATVTLAERGRMEVLGGED
                     VRIINDAYNASPDSTAAALRTLAQIAKPGGRTVAVLGEMSELGEWADEEHERVGLLAVR
                     LNISQIVVVGRGARRIHVAAEREGSWSGESVFAETSDEAFDLLEDYLRPGDTVLVKSSN
                     SAGLRFLADRLGERHR"
     gene            18881..19975
                     /gene="mraY"
                     /locus_tag="C5C56_RS00485"
                     /old_locus_tag="C5C56_00485"
     CDS             18881..19975
                     /EC_number="2.7.8.13"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="mraY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_4"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013583197.1"
                     /locus_tag="C5C56_RS00485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00485"
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="WP_104222591.1"
                     /sec_met_domain="Glycos_transf_4 (E-value: 4.8e-33,
                     bitscore: 108.8, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALLLSGAFSGAFTLLMTPLFIRLFHRLQWGQFIREDGPKSHHV
                     KHGTATMGGIVIIIGTVVGYFLGMLFGNRAIAPSALLVLFMMVGLGLVGFVDDFLKTRN
                     QRSLGLGGWAKIAGQVIVAAAFAVIAIMVRDSNGLTPASTSISFIRDLPFDFASLGWIG
                     IGLFVLWICIIVTSTSNGVNVADGLDGLATGSSILAIGSYVIIGFWQSNQWCFDQHLNP
                     EVVDKCYQVSDPFDLAIIAAAVSGALVGFLWWNTSPAQIFMGDTGSLGLGGALAALAIL
                     TRTELLVILIGGLFVIVTGSVILQRIYFKLTRGKRIFLMSPLHHHFELKGWAEITVVVR
                     FWIIAGIFVAAGVGLFYLEWLSLA"
     misc_feature    complement(20765..20780)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.68"
                     /tool="antismash"
ORIGIN
        1 gcgcgaccgt gtgttcggcc ggatcgacgc gatcagcgag ggcggtttcg agtaccgcga
       61 tcagcgctcc ccgaacgtga ccgtcctccg cgagagcttc ggcttcgagt cgctcggaga
      121 cggcgaccgc ccgcacgtcc tcgtcagcgc cagcggtgcc cgcatcagtg ctccgcaggt
      181 ggtcgtggcc gccggctcgc ggcccaggcc gctcctcgcc gcgtacgagc cggacccccg
      241 catccaggac tcgtcctcgg tcatgcggct cgacgagctc cccgagcgga tgctgatcct
      301 cggcggcggc gccgtggccg tcgagttcgc ccacgtcttc tcctccttcg gcacggccgt
      361 gaccgtcgcc gtccgcggcg accgcctcct ccgcgccctc gacgaggacg tctcgcgccg
      421 gttcaccggg atcgccgccg agcggtacac ggtgctcacc ggagtgagcg ccgagagcgt
      481 cgacgcccgc cctgacgggc tccgcgtcgc cctcagcgac ggcacgacgg tcgagaccga
      541 cctgctgctc gtcgcgctcg gccgcgaccc caacagcgac acggtcgccg ccgcctccgt
      601 cgggatcgat ctgcacgagg acggccggat cagcgtcgac accgagcagc gcgtcctctc
      661 cggcggacgc cccgtgcccg gcctcttcgc cctcggcgac gtgtcgtcgc gctggcagct
      721 caagcacgtc gccaaccacg aggcgcgcct cgtggcgcac aacctcctgc acccgggcga
      781 gctgctctcc aacaccctct cgccggtgcc cggcgcgatc ttcgcccacc cgcagatcgc
      841 ccacttcggg ctcaccgcgg ccgaggcgcg ggaccagggc ctggacgtcg tcaccgtcac
      901 ccaggagtac ggctccaccg ccttcggctg ggcgctcgag gacgactcca gcgcctgcct
      961 cctggtcgtc ggcatcgacg gcgccctcct cggcgcgcac atcatcgggc cgcaggccag
     1021 tatcctcatt cagccgctcg tccaggccgc cagcgccggc accggcatcc gcggactcgc
     1081 ccgcagccag tactggccgc accccgcagc gagtgaagtc gtcgagaacg ccctcctgag
     1141 cgcggaggag gccctgaggg agcgcaccac atgaccgaac gccagatccg catcttcggg
     1201 gacccggtgc tgaagacccg gtccacgacc atcgagacgg tcgacgtcgg cgtccgcggc
     1261 ctcgtcgagg acctcgtcga cagcgtccga ccgcccggac gcgccggcgt cgcagccccc
     1321 cagatcggcg tcaacctccg cgccttcagc tacaacgtcg acggcgtcat cgggtacatc
     1381 ctcaaccccg agatcatcga gctcagcggg gacccgcgac cggtcgacga gggctgcctc
     1441 tccgtcccga acctctggta ccccgcgatc cgctacccgc acgcgaaggt ccgcggcacc
     1501 gacctcgacg gcaacgagat cgtcctcgaa ggcgacggcc tcatggccca ggccctccag
     1561 cacgaatgcg accacctcga cggacgcctc tacctcgacc gcctctccca ggacgaccgc
     1621 cgcgccgcca tgaaggccgt ccgggaatcc gactggttct gagttcgatt ccgggccggt
     1681 ccctgcccgg cccggcgcgg tcggcttttc gaggtgggcg cgttcggtgg agcgtcgtgc
     1741 gttccgccga cggtgaagcg ctggcacgcg cttcaccgga tacggctgcg ttgagggggg
     1801 agccggtccc tgcccggccc ggcgcggtcg gctcagcgag gtgggggcgt tccgtggagc
     1861 gtcgggcgtt ccgccgacgg gaaagcgctg ggacgcgatt tcccggatac ggctgtgttg
     1921 agggggagcc ggtccctgcc tggctccgcg cggtcggctt ctcggggtgg gcgcgttctg
     1981 tggagcgtcg tgcgttccgc cgacgggaaa gcgctgggac gcgcttttcc ggatacggct
     2041 gtgtcgaggg gagccggtcc ttgcccggct ccgcgcggtc ggcctttcga ggtgggcgcg
     2101 ttccgaggag cgtcgtgcgt tccgccgacg ggatagagct gggcgcgctg tcccggaggc
     2161 ggctgcgatc gggacggcct gctggtgacg gcgggagagc gcggggtcag cggagggaga
     2221 tgccctcggt ggcgggggcg gcggagtaga cggcggcgat ggtgtcggcg aagtcggcga
     2281 ggatgacgtt gcgcttgatg ctcatcttcg gagtcaggtg accgctcgcc tccgtgaact
     2341 cggtcgggag gatcacgaac ttccggatcg actcggcgcg ggacacgcgc tcgttcgccg
     2401 catcgacggc ccgctgcacc tcggccagaa cgaccgggtt cacggccgcg tcctcgagtg
     2461 agaggccctt gtcctgcccg ttgttggcga gccacgtcgg cagcatctcg gagtcgagcg
     2521 tgaccagagc agcgatgaac gggcgctgat cgccgacgac gacgacctgg ccgaccagcg
     2581 ggttcgcgcg gatcggatcc tccagcgccg ccggagcgac gttcttgccg ccggcggtga
     2641 cgatgatctc cttcttccgc ccggtgacgc gcaggtaccc gtcctcgtcc agggttccga
     2701 ggtcgcccgt gcggaaccac tcgccgtcga acgactcggc cgtcgccgcc tcgttgttcc
     2761 agtagccgcc gaagacgtcg atgccgcgca cctggatctc gccgtcgccc gcgatccgga
     2821 tcgagacgcc gggcatcgcc gggcccaccg agccgatctt gaaacgctcg gtgcggttga
     2881 ccgtggcggg cgccgtcgtc tccgtgaggc cgtagccctc gaggatcttg atgccgaggc
     2941 tgtggaagaa gtgcccgagc cggtctccca gcggcgccga gccggacacc gcgaagcgga
     3001 cgttcccgcc catggcggtg cgcagcttcg agtagacgag ccggtcgaag aggaggaact
     3061 gcagcttcag cgcgagcggc accgagcccg cctcgagcgc catcgagtgg gcgacggcga
     3121 cgtcggccgc gcggcggaag atcttcccct tccccccggc ctcggccttc tgctcggcgg
     3181 agttgtagac cttctcgaac acgcgcggca cggccaggag gaacgtcggc ttgaaggacg
     3241 cgagcgaggg gagcagctgc ctggtgtcgg cctggtgccc caccttcacc ccgccgtgca
     3301 cgcagaggat cgcgatgaag cgggcgaaca cgtgcgccgt ggtgatgaac agcagcgtcg
     3361 acgcgccggg ctggtggatc agctccgtca gggcgaccgc cgagttgcgg ctgagctcga
     3421 cgaagttcga gtgccggatg atgcagccct tggggcggcc ggtggagccg gaggtgtaga
     3481 tgatcgtcgc gatgtcggtg ccggtcgcca gcgagcggcg gcgctcgatc tcggcgtccg
     3541 gcacgtcgac gccgcgcgcg acgagcttgt ccagatcgcc cagcccgatc tgccaggcga
     3601 gtcggacctc gggaaggtcg gcgcggatct cgtcgaagcg ggcgaagtgc tcgggagtct
     3661 cgacgatcac ggcgtgcgcg ccggagtcgg cgaggttcca ctgcacctgc gcgggggagg
     3721 aggtctcata caccgggacg aggatcccgc cggcgaacca gacggcgaag tcgatcagcg
     3781 tccactcgta gcgcgtcttg cagatcagcc cgaccttctc gcccggctcg aggccggcgg
     3841 cgacgaagcc cttcgcgagg gccgtgacct ggtcgaggaa ctcctgcgcc gtcacatcgc
     3901 gccagccgtc gccgtcgggc agcgcgaaga gcgggcgatc gggtgtctcg cggacgcggt
     3961 ccagcaggag ggcggtcgtg ttggcctggg gatcggccgg aaccaccagg ggggaatcga
     4021 actggtccac ggcaactcct tcggtacctg aatgaacgtc gtctccaccc taccggcgcg
     4081 gcgcaagctg tggatccgtt cagggtaacg atccaggggt ggctccgcga ggagggccga
     4141 cacgcgtcgc cgggtctcgc cgctgagccg catcggagcg ctcgcggtca ctacactcgt
     4201 cctggccgcc gctcagggcg gcccgccgac gctgccgcgc cggtggcgac gggaaggcgg
     4261 ttcgcgtgca cgcgatcggg atcgacatcg gcggcacgaa gatcgccgga gccctggtcg
     4321 acgagttcgg ggggatcctc cgcgaggacc gtcggcccac tcctgccggg caccccgagc
     4381 tgatcgtcga cgtcgtggtc gagatggtcg agcatctgcg ctccggcctg ctcccgggag
     4441 acgtctccgc ggtcggagtc gccgccgccg gcttcatcga cgcctcgcag tcgatcgtct
     4501 actacgcccc gaacatcaac tggcgcaacg agcccttccg cgagaagctc tcggcccgca
     4561 tcgacctgcc gatcatcatc gagaacgatg cgaacgccgc cggctgggcc gagttccgct
     4621 acggctcggg ccgcctcgtc agcgacatgc tgatgctcac catcggcacc ggagtgggtg
     4681 gcgcgatcgt catcaacgac cggctcctgc gcggcggctt cggcgccgcg gccgagatcg
     4741 ggcacatgcg cgtcgtcccc ggaggcctgc cctgcggctg cggcgcccgc ggctgcatcg
     4801 agcagtacgg ctcgggccgc gcgctccagc gcttcgccgg cgagctggcc gacgcgggcg
     4861 ggatcggcca gggcatcgcc gacgcccgcg cccgcaacgg cggcgagctg aacggccacc
     4921 tcatctccga gctgatcacc gctggcgacc tcggcgccct cgcggcgctg cgacagctcg
     4981 gccactggct gggcgaggcg gcggccagcc tgagcgccgt cctcgacccg cagatgttcg
     5041 tcatcggcgg cggagtggcg caggcgggcg acctcctgct ggaccccatc cgccaggcct
     5101 acctcgacaa cctccccgcc cggggctacc accccgagcc cgagttccgc atcgcggagc
     5161 tcgtcaacga cgccggagtc gtgggggccg ccgacctggc gcgcctgcac gcgagctccc
     5221 tctagcggca cccgccgcac ccgatccgcc gcaccgccga ggagcccgat gttctactgg
     5281 ttcatgaagc acatcgtcgc gggcccgctc ctgaagacga tcttccggcc gtgggtggtc
     5341 ggcgccgaca aggtgccgca gaacggcggc gtgatcctcg cgagcaacca cctctccttc
     5401 atcgactccg tgatcctccc gctggtgatc gagcggaaca tggtcttcct cgccaagagc
     5461 gactacttca ccggcaaggg cctcaagggc tgggcgacgc ggacgttctt caccgccacg
     5521 gggatgctgc ccatcgaccg ctccggtggc aaggcgtcgg aggcctcgct caacacgggc
     5581 ctccgcgtcc tcgcgggcgg ccacgccctg ggcatctatc ccgagggcac gcgcagcccc
     5641 gacggccgga tgtaccgcgg ccgcaccggt gtcgcgcgca tggtcctcga ggcccgcgtg
     5701 cccgtcatcc cggtcgccat gatcgacacc gcgcgcatca tgcccatcgg caagcgcctg
     5761 ccgaagctgg gccgcatcgg catcgtcttc ggggagccgc tcgacttcag ccgcttcgag
     5821 ggcatggagg gcgaccggtt catcctccgc tcgatcaccg acgagatcat gtacgagctc
     5881 ctcgccctga gcggccagga gtacctcgac gtctacgcga cctcggtcaa ggagaagcgc
     5941 gcggccctca cccgctgagc gcccgctcga cgccggggcc ccctcccggc cgagcgccct
     6001 gccaggcgat aagctcgtca accgctgccg tccgtccgga cggcggccct ccgcgcgccg
     6061 ctggcgcccg tcagaaccgg gaacaccctc gtggtcatcg atccgaacga accgtacgtc
     6121 ctcgccgccc cctccgtggt cgccggcctg gactattggc gcgagctcga gatcaagcag
     6181 cagccgcagt ggcccgatgc ggaggccgtg cgagcggcgt ccgccgaggt ggccgcgctc
     6241 cctccgctgg tgttcgccgg cgaggtggac cagctgcgcg agcgtctcgg agccgcggcc
     6301 cgcggcgagg cgttcctcct gcagggcggc gactgcgccg agaccttcgc aggagcgacc
     6361 gccgagcaga tccgcaaccg cgtcaagacc gtgctgcaga tggccgtcgt cctgacctac
     6421 ggcgcgagca tgcccgtcat caagatgggc cggatggccg gccagttcgc gaagccgcgc
     6481 tcgagcgacc tcgagacccg cggcgacgtg accctgcccg cctaccgcgg cgacatcgtc
     6541 aacggctacg acttcacccc ggagtcgcgc gccgcggacc cgcgccgcat cgtgcagggc
     6601 taccacaccg ccgcctcgac gctgaacctc atccgcgcct tcacgcaggg cggattcgcc
     6661 gacctgcgcc tcgtccacta ctggaacaag ggcttcaccg agaacccgca gaaccagcgc
     6721 tacgagcagc tggcccgcga gatcgaccgc gcggtcaagt tcatggtggc gtgcggggcc
     6781 gacttcgagg gcatgaagcg caccgagttc tacaccggcc acgagggcct gctgatggac
     6841 tacgagcgcc ccatgacgcg catcgactcg cggaccggca cgccgtacaa cacctccagc
     6901 cacttcatct ggatcggcga gcgcacccgc gagctcgacg gcgcgcacgt cgacttcctg
     6961 tcgcgggtgc gcaacccgat cggcgtgaag ctcggcccgt cgaccacgcc cgagacgatg
     7021 ctcgagctga tcgacaagct cgaccccgag cgggagcccg gtcgcctcac cttcatcacc
     7081 cgcatgggtg ccgggaggat ccgcgacgcc ctcccgccgc tgctcgaggc cgtcaagcgg
     7141 agcgacgccc tgccgctgtg ggtgaccgat ccgatgcacg gcaacgggct gacgacgccg
     7201 accggctaca agacccgtcg cttcgacgac gtggtcgacg aggtcaaggg cttcttcgag
     7261 gcgcaccgcg ccgcggggac gcacccgggc ggcatccacg tcgagctcac gggcgacgac
     7321 gtcaccgagt gcctcggcgg ctcggagcac atcgacgagg cgacgctcgc cacccggtac
     7381 gagtcggtct gcgacccgcg cctcaaccac atgcagtcgc tcgagctcgc gttcctcgtg
     7441 gcggaggagc tccggggccg cgcgatctga tccgaccccg accgccggtc gagtcctcgt
     7501 tgagagctcg accggcggcg tcaggtcgtg atggtgatcg acagctggat cgtcgtgccg
     7561 cgctgcacga gatcgccggc cttgttggac tggttcgtga ccttggtcag ctcgttcggc
     7621 gccgcgtcga tcagcgggcc gagcgtcgtc agggagtagc tccacgacag gtccgccgcc
     7681 tcgagggccg ccttcgcctc gtcgcggttc atccccacga cgttcggcac ggcgacgggc
     7741 tcgggcccct tcgacacgac gaccgagacg gtgtcgccgg tcacggcggg cgcctccggg
     7801 ttcgcctgcg tgaggacgac gcccgcggcc acggtgtcgc tccagtcctc gccgctgcgg
     7861 tcgagggcga gaccggccgc ctccgccttc gccgtcgcgt cgtcgatcga gaggccgacg
     7921 acgttcggga tcggtccgag gctcaccacc atcgcgatgg tgctggtctc ggacatcgtc
     7981 tcgggcagcg ccgatccgtc aggcagcgac gcggagacga ccacaccggc gtcgacgtcg
     8041 gcgtcgaaga tcttcgagac gtcgccgacg gtgaaggagc cgcccgtcac cgcggcggca
     8101 gcgtcggcct ccgagaggcc tgcgagagac gggaccggca gctggcgcgg cccgctcgag
     8161 acggtcagcg tgatgacgga gcccttgtgc accccctgcc cgccgggcgg atcggagctc
     8221 acgaccgtcc ccgcgggcac ggtgaggtcg ggcgtctcct gcggctgcac ctcgaagccc
     8281 tgcgcctgca gctgggccgt cgcgtcctgc tgcgactggc tgacgacgtc cgggatcgac
     8341 acgatcgcgc cgggtccctc gccgaaccac caggccgtcc cgccgccgat gagcgccagg
     8401 aggaggacga ccaccgtgag caggacgccg cggcgccgtc ggacgcggcg cctgctcgcg
     8461 agccgggcga cggtgtcgtc gtcctcgtcg accacgagca ccgctccggg ggccggcgcc
     8521 gggtcgaaga ccgaggtctg cccgggctcc gccgtatcga agacggccgt cgcgggcgcc
     8581 ggatcggcga cgggcgccgg gagcggggtg accgcctgcg tgtcgccgcg ccggtcgctc
     8641 ggtgtgatgt ccatgagccg ctcggcctcg agcagctgcg cgagcatgac accggcgtcg
     8701 cggggccgca tgtccgggtc gcgctcggtc gcccagagga cgagctcgtc gagcgaggtg
     8761 gggacggagg cgaccgtcgc gctggggtac gggacggagt cgttcgcgtg ctggtacgcg
     8821 atctgcatcg gctgctcgcc cgtgaagggc tgctctccgg tgagcatctc gtagatcatg
     8881 atcccgatgg cgtagatgtc gctgcgggtg tcggcggtgc cccgcgtgac cagctcgggg
     8941 gagaggtagg cgatcgtgcc gaggagggcc tgaccggagg cggtgttggc ggaggcggcg
     9001 cgcgcgaggc cgaagtcgcc gatcttgatc cggccgtcgt cggcgaggag cacgttctcg
     9061 ggcttgaggt cgcggtggag gatcccggcg cggtgcgcgg cggcgagacc cgagagcacg
     9121 gagtgcatga tgtcgacgac ctgctgggcg gtcagtcggc cgcgctcctt gagcaggtcg
     9181 cgcagggtga tcccggggag gtactccatc accaggtagg ccatgtccga gtcctggccc
     9241 tggtcgaaga cgctgaccac gttcgggtgg gcgagacggg cggcggagcg cgcctcctgg
     9301 acgaagcggt tcttgaacgt cgcgtcgtcg gagaggtggc cgtgcatgac cttcatcgcc
     9361 acgcggcgct cgaggcgctg atcgtgcgcg aggtagaccg tcgccatgcc gccgcgggcg
     9421 atcctcgagc gcacctcgta ccggccgtcg acgagacggc cgaggagagg gtcgagctgg
     9481 ctggtggtca cgcgacgagt ctaggcaaga cccccggggg aaccggtgag cgacgcccgg
     9541 gcggcgcagg acgggcccga ctccttctcc ggggcgcccg cagttggcgg ccctccgggc
     9601 tcgtggcagt cttgacgcgt gaccgactcg tccgcttccc ccgccacctc gaccgattcc
     9661 gagctcgagt ggctgaccgt ccccgacctc gtggagctga ccgggctcgg cgccggccgg
     9721 gtccgccgcc tcctcgagga gcgccacctg ctcggcaccc gccgcgacgg cgtgctgaag
     9781 gtccccgccc tcttcctccg cgacggggag ccgatgagcg agatccgcgg caccgcgatc
     9841 ctgctcgccg actccggctt caccgacgac gaggcggtcg actggatgct gacggtcgag
     9901 gagagcctgg gcacgagccc gatcgtcgcc ctccgcgctg gccgcaaggc cgaggtccgg
     9961 cgggtcgccc aggccctggc ctgatcccgc cggtccgctc ctaggaggtg cggaccgtga
    10021 cctgggctgc cagctcgcgc agctccgcca cgccctccgt gcggagcggc gcgtcgggga
    10081 ggaccgcgat cgccgcggcc acctcctggt cgatgcgctc ctcgagccgc tcgagggcgc
    10141 cgctgcccgc gatgatctcc tgcgcccgcg cgatggacgc cgcgtcggcg tcgctccggc
    10201 ccacgaccgc gtcgagctcg gcccgctcgc ccggcgagca cgcgccgcgg gcgaggccga
    10261 gcagcacggt gcgcttgccc tcccgcagat cgtcgccggc cggcttgccc gtcactgccg
    10321 ggtcgccgaa gactccgagg acgtcgtcgc gcagctggaa ggcgatcccg accgggagcc
    10381 cgaagcggcg cagggcgtcc agctgagcgt cgtcgccgcc ggcgagggag ccgccgatca
    10441 ccagcggcgc ctcgatgctg tacttcgcgc tcttgtagac caccacccgc tccgcccgct
    10501 gcaggtgctc gtgctcgggg tgctgcaccc acgcgctctc ctcgaggatg tcgaggtact
    10561 ggcccagcgt gacctcggtg cgcatcaggt tgaactccgc gcgcgcgcgc tcggctgcga
    10621 ctcgatcccc gagcgaccac tccgccgcgg cgaagatctc gtccgaccag accaggagga
    10681 ggtcgccgag gaggatcgcg gaggagcggc cgaactcgtc gcggtcgccg gtccagccgc
    10741 cgtcggcgtg gaaggaggag aagcgccggt gggccgcggg agcgccgcgg cgggtgtcgg
    10801 agttgtcgat cacgtcgtcg tggacgaggg cggcggcgtg gaacagctcc agcccggcgc
    10861 ccaccctcgc gatcggatcg gagccgctcg gatgggcctc gctcgaggtg ctcgacaccg
    10921 cgttccagcc cgcctcgcag aagcgcgcgc ggaaccgctt gcccccgctg agaaagtccc
    10981 gcgaaaggtc gccgagggcg gagacgtcct ctcctatgga gcgcagaatt ggcgtgcgcc
    11041 cggtgaggaa ttcatcgatt cggagctgga cgcgatcgac cagtcgagag ctgtggttca
    11101 cccgaccagc ctatgcaccg aaggtgcctg gtgcctgcgt cgggctcggt ctacactgaa
    11161 gcgccgcccg accggtcgag cccagacgcc gcctattccg gtgccgatcc ccgaaagggt
    11221 cgacgccgca ccctgaaggg gtcacgatgc cgctttcgga acacgagcaa cggctcctcg
    11281 atgagatgga gcggaacctc taccagaacg acgccgattt cgtggcggcg gtcggcaagg
    11341 ggcgcggcgg caccaactac cgggccctcg tgctcggcat cctgctcggc atcctcggtc
    11401 tcgccgtgct cgtcgcgggc gtggtcgtgc gccagcccct cgtcggcatc ctcgggttcg
    11461 ccttcatgct cggcggcgtg atcgtggcca tgcgcccggc cgccggcggc tcctccgcgc
    11521 ccggcctgcc cgacgtcggc cgtccgtcga agccccgctc gggcaaccgc caggggtccg
    11581 gcttcatgga ccgtctgaac gacaggtggg acaaccgcgg agacgggcgc ggctagcctc
    11641 ccctccgctc caccacaggg tcgatcctca cggatcggcc cttttttcgt gcccgcggcc
    11701 tccctcccgc ggccctcccc ctccacttct ccccactgtc gcgattccgc ggaaacacgc
    11761 ggatgaccgg ggcctctccg gcgcgccccg cgccgcgccg gggttgtgag tggggggaag
    11821 tggagtactg tggaggacac accatccttg gccggaagaa gtgggggggg cagtccgtgt
    11881 tcctcggcac ctattccccc aagctcgacg agaagggccg cgtgatcctc cccgccaagt
    11941 tccgcgacga gctctcctcc ggagtcgtcg tcacgcgcgg ccaggagcgg tgcctgtacg
    12001 tgttcagcca ggccgagttc gaggtcatgc acgagaagat ccggcaggcg ccggtgacca
    12061 gcaagcaggc gcgggacttc ctccgggtgt tcctctcggg cgcgagcgcc gagacgccgg
    12121 acaagcagaa ccgtgtgacc ctcccggctc cgctgcgcgc ctacgcgggc ctcgaccgcg
    12181 acctcaccgt catcggagcg ggcaaccgcg ccgagatctg ggcgcagggc gcctgggaga
    12241 cctacctgca ggagcaggag tccgtgttct ccgacaccca ggaggaggtg atccccggcc
    12301 tgttctaggt cctgtcgcgc gactcccagc cactcggcgc ccggacgcac cttccccggt
    12361 gtccggacgc gaggtggatg gggatcggac gacaggaacg ggaacggcgg gaccgccatg
    12421 gcagagaaca ctccgaaggg cgctccgcgc ccgaccgagg agcggcacct cccggtgctg
    12481 ctcgagcgct gcgtcgagct cctggctccg gcgctggagc gcgacggggc ggtcgtcgtc
    12541 gacgcgacgc tcggcatggg cgggcactcg ctcgcgctgc tcgagcgctt ccccggcctg
    12601 cacctcgtgg gcctggaccg cgaccccgag gcgctgcagc tcgcggggga gcggctctcc
    12661 gcccacgcct cccggatcga cctcgtgcac gccgtctacg acgagctgcc cgacgtgctc
    12721 gacgagctgg gcatcgacac gatcgacggt gcgctcttcg acctcggcgt ctcctcgctc
    12781 cagctcgacg agaccgagcg cgggttctcc tactccaagg acgcgccgct cgacatgcgg
    12841 atggactcga ccgccccgct cacagcggcg agcatcctcg ccgactacga cgagaccgcc
    12901 ctgcgccgca tcttccacga gtacggcgag gagcgcctcg ccgcgcgcta cgccaagaag
    12961 atcgtggagg cccgtcgcga ggctccgctg gagcgctccg gccgtctcgt cgagatcatc
    13021 caggcggcga ccccggtcgc gatccagcgg aacggccacc ccgccaagcg cgtcttccag
    13081 gcgctgcgga tcgaggtcaa ccaggagctg tccgtcctcg agcgggcgat ccccgccgca
    13141 ctgggccgga tcaacgaggg cgggcggatc gtcgtcgagg cgtaccagtc gctcgaggac
    13201 cggatcgtca agcgcgcgct ccaggccgcg tcctcctcca ccgccccggc cggcctcccg
    13261 atggagctgc cggagcaccg acccgagttc cgactcgtca tccgcggagc cgagctcgcc
    13321 tccgacgacg agaaggcccg caacccccga gcgacacccg tgcgtctgcg cgcggccgag
    13381 aggatcagga gcaccgcatg agcgccaccg ccgtcatcga ccccgccgtc atcgacaccg
    13441 cccgccgagc acgccccgag gaggaggcgc cccgcccccg catcgaggcc gtcccggccg
    13501 gtcaggcgca gtcgcgcccg aagctcgtct acgggatcgt cgccgtcgcc ggcctcttcg
    13561 cgatcatcgt cgtccagctc ctggtgagcg tcggcctctc gcagggggcc taccagatct
    13621 cggcgctgca gaccgagcag aagtcgctca cccgcagcaa cgcggagaag caggacgccg
    13681 tcgacacgct gagctcgccg cagaacctcg ccaccgccgc tcagggcctg ggcatggtcg
    13741 ccaacaccgc gccggtctac ctccgcctct cggacggcgc cgtgctgggc gacccctcct
    13801 ccgccgcgtc gagcgaagtc gcgggcaccg cctccgcgcc gctcgtgccc aacgccctcg
    13861 tcccggctct ccagcccggc gcgagcgcgt cctccccggc tgtcgacggt gcggccgtac
    13921 cgttgcaggg cgagctgccc gcgcccatca cgcactgacg cacggcgtcg cggtccgcct
    13981 ccgtgcgggc acccgccccg cggggcgcac gacgaccatc cggacccgac gaacggcggc
    14041 ccgcccgccc ggagcaagaa ggacaccgcc gcagtgagac accaccgctc gagcagacgc
    14101 cgcacggccg tcacgttcgt catcatcgtc gccgtcgtcg gactcttcat cggcaagctg
    14161 gtggacatcc agatcgtgcg ggcgaacgag ctcaccgatg cggccgccca gaaccagtcg
    14221 aacagcgtcg tcacctacgg tcagcgcggc cccatcgtgg accgctccgg gacggtgctc
    14281 gcggacacca ccacgcgcta ccggctgacc acctcgccga agaacgtggc cgagttcccg
    14341 cgcgagctgg gcgaggacca gaaggtcatg gtcagcgtgc agcaggccgc ctccgagatc
    14401 ggcgcgatca ccgggcagtc ggtcgagcag atcaccggag cggtggacgc cgcgctcgcg
    14461 aaggacgcca aggccaacta cctgatcctc tcggaggggc tcgacctcga ggcctaccag
    14521 aagctcgtcg cgctcgacat cccgtggacc tacttcgaga cccagcaggg acgcagctac
    14581 cccaacggcg cggtggccgg caacctcgtc ggctacgtcg gggcggacgg agcggcccag
    14641 gagggcatgg agtacgcgga gaacacctgc ctcgcggggc agaacgggtc cgagagctac
    14701 gagcgcagcg ccgactacgt ccggatcccg ggcagcaccg tctcggagac cccggccgtc
    14761 gacggcggga cgctgaagct caccatcgac tccgacctcc agtactactc ccagcaggtc
    14821 ctctcgcagc gcgtcgccga ggtcggcggc agctacggga tcgtcgtggt gcaggaggtc
    14881 aagaccggca agctgctcgc cgtggccgag acgccgaccg tcgaccccaa caacgtcgag
    14941 gcgagcgcct ccgccgaccg cagctcgcgc gcgttccgcg cgccgttcga gccgggctcg
    15001 accttcaagc cgatgacggc cgcgatgctg atcgaccagg gccaggcggg cccgacgacc
    15061 caggtcgtcg tcccggactc cttcgagaag gacggcgcct cgttcagcga cgacttcgcg
    15121 cacaccccga cgaactacac gctgaccggc atcctcaagg actcgtcgaa cgtcggcatc
    15181 tcgatgctcg gctcccgcct gtcggcccag acccgctacg actacctgca gaagttcggt
    15241 ctcggcacgc ccactacgag cggcttcccc ggcgaggagg gcggcctgct cgccgactac
    15301 caggactggg acaaccagac gaactacacg acgatgttcg gccagggcgt ctcggcgacc
    15361 gcggtgcagg tcgcgagcat ctaccagacg ctcggcaacg gcggagtgcg gctcccgtcg
    15421 cagctgatcg acggctgcac cacggccgac ggctccgtcg tggacgtccc cgatgcgacg
    15481 ggcacccagg tggtgtcgag ctcggccgcg aagcaggtcg tcgacatgct gcagacgcac
    15541 tacaacgagg gctggctggc gaacgacatc cacgtcgacg gctacaacat cgccaccaag
    15601 accggtaccg cgcagcagcc cgacggcaag ggcggctact cgaagagcta caccgtctcg
    15661 ctcgccgggc tcgcgccggc ggaggacccg gagtacgtcg tgacggtcac catcgccgat
    15721 ccggttaaga tgaacacgtc ccaggcgacg gctcccgtct tccagcaggt catgacccag
    15781 gtgctcaaga ccaaccgggt ggagccgtcc acggtgccgc ccgtcgagta cccgacgacg
    15841 tggtgagccc cgccgggacc acgatccacg caccagaacg agagaaagag cgggcagtgc
    15901 acgaccctcg cccgcagtcc tccctccgcc ccgagcaccc cgtgccgcgg agcctctcgc
    15961 agctcgtggc cgagttctcc ctcggcccgg tccgcggcct cgagggcgtc gaggtgagcg
    16021 gagtcacgct ggactcgaac caggtcgagt ccggggacct ctacgtcggt gtcgcaggac
    16081 gccgtgccca tggcgcggcc ttcgcgtcgg ccgccgcggc gtccggagcc gtcgccgtgc
    16141 tgaccgaccc cgccggagcg gagctcgccg ccgacagcgg cctgcccgtg ctggtgactc
    16201 ccgacccgcg ggccgccctc ggcgacgtcg ccgcgtggat ccaccggacc cgcgaggacg
    16261 tcccgacgct cttcggcgtg acggggacca acggcaagac gagcgtcgtc tacatcctcg
    16321 acgcgctgct gcgccggctc ggagtcgtct ccggcctcag ctccaccgcc gagcgccgga
    16381 tcggcgacgt cgccgtggtc agctcgctga ccactcccga ggcgagcgag ctgcacggcc
    16441 tgctcgctcg gatgcgcgag tccgccgtcc gcgcggtctc catcgaggtg tcggcgcagg
    16501 cgctcacgcg gcaccggatc gacggcctcg tcttcgacgt cgtcggcttc acgaacctca
    16561 gccacgacca cctcgacgac tactccgatc tgcgcgagta cttcgaggcc aaggccgacc
    16621 tcttcgagcc ggagcgcgca cgccgcggcg tcgtcacggt cgacagcgcc tgggggcgcg
    16681 agctcgccga gcgcagccgc atccccgtcg cgacgctcgc cggctctccg gtcgtcggag
    16741 tcgccccgac gacgcctgcc gactggtcga tgacggtgct ggacgcgacg cccgacagca
    16801 ccaccttccg cctggagggg cccgagaacc gctccgtcgt cgtcaccgtc tcgctgatcg
    16861 gctggtacat ggcgtccaac gccgcgctgg cgatcgtgat gctggtggag tcgggcttcg
    16921 acctggacgc cgtcgcgcac gcgctcgagg acagccgtct cgacgtctac atcccgggcc
    16981 gcgcagagct cgtctcgggg gagcgcggac cgcgcgtcta cgtcgactac ggccacaccc
    17041 ccgacgcgtt ccagaacgcg ctcgaggcgc tgcggaccat cacgcctggc cgcctgttca
    17101 tggtgttcgg ggcggacggg gaccgcgaca cgaccaagcg gagcgacatg ggcggcatcg
    17161 ccgcccgcct cgccgacgtc gtggtcgtca ccgacttcca cccgcgctgg gaggatccgg
    17221 ccgccatccg cgccgcgctc ctccagggcg cccgggccgc cgtgcccgac cgggagatcc
    17281 acgagatcgc cgacccgcgc gccgccgtgc gcgccgccgt cgccctcgcg cgcgaagggg
    17341 actcgatcct ctacgccggg cccggccacg aggaccacca ggagatcgca ggagtgcaca
    17401 tgccgtattc ggccagagac gacgtccgtc acgcgctgcg cgaggcgggc tggctgtaga
    17461 tgatcgccct caccctcacc gagatcgccg aggccgtctc cggacgcctc cacctggccg
    17521 gctcgtccgc cacggccgcc accgtgatcg acggagcgac cgagaccgac tcccgcgaga
    17581 tcgcgcccgg cgggatcttc gtcgccaagc gcggcgagca caccgacggc cacctcttcg
    17641 ctcccgccgc tctcgagcgc ggtgccgcgc tcctcatcgt ggagcgcccg ctcgacctcg
    17701 acgtgccgca ggtcctcgtc gacgactccg tggaggcgct cggcgcgctg gcgaccgagg
    17761 tcgtccgccg cgtccgcgcg aagggcgggc tcaccgtcat cggcgtcacc ggctcgaacg
    17821 gcaagacgac gaccaagaac ctcctccgca ccgtcctcga gcgggtcggc gagacggtcg
    17881 ctccgcgcgg atccttcaac aacgaggtcg gcgcgccgat cacgatgctc caggtgtccg
    17941 agtcgacgcg cttcctcgtc gccgagatgg gcgcgagcgc ggtcggcgag atccgccgcc
    18001 tcgtccggat ggccaggccc gacgtcggcg tcgtcctcgc cgtgggcctc gcgcacgccg
    18061 gcgagttcgg cgggatcgag cgcacgctcg aggccaagac agagatggtc gccgacctca
    18121 ccgccgacga cgtcgccgtg ctgaacgccg acgacggccg ggtcgcctcg atggcgggcc
    18181 gcaccgccgc ccgggtcctc tggttcggcc gcggcgagag cgcggacgtc cgcgccgtcg
    18241 atatcgacgc gaccgccgac ggcacccgct tcgccatcga ggtctcggcg ggggagggcc
    18301 gcgaggccgc tcgcgccgag ctcctgctgc gcgtcctcgg cgagcaccac gtgatgaacg
    18361 ccctcgcggc gaccgccgcc gcgctctctg tcggagtggc gctgcccgcg atcgtcgagg
    18421 ctctcgcgac cgtcaccctc gccgagcgcg gccgcatgga ggtcctgggc ggcgaggacg
    18481 tccgcatcat caacgacgcg tacaacgcga gtcccgactc caccgcggcc gccctgcgca
    18541 ccctcgctca gatcgcgaag cccggggggc gcaccgtcgc cgtcctggga gagatgagcg
    18601 agctcggcga gtgggccgac gaggagcacg agcgcgtggg cctgctggcc gtgcgcctca
    18661 acatctccca gatcgtggtg gtgggccgag gcgcccgccg gatccacgtc gcggccgagc
    18721 gcgaggggtc gtggagcggc gagtccgtct tcgcggagac ctccgacgag gcgttcgacc
    18781 tcctcgagga ctacctgcga cccggcgaca ccgtgctggt caagtcgtcc aactccgcgg
    18841 ggctgcgctt cctcgccgac cgtctcgggg agcgtcaccg atgagggcac tcctcctgtc
    18901 cggcgcgttc tcgggagcct tcacgctcct gatgacgccc ctgttcatcc gcctcttcca
    18961 ccgcctgcag tggggccagt tcatccgcga ggacggaccg aagtcgcacc acgtcaagca
    19021 cggcacggcg acgatgggcg gcatcgtcat catcatcggc accgtggtcg gctacttcct
    19081 cgggatgctg ttcggcaacc gggcgatcgc gccgtcggcc ctgctggtgc tcttcatgat
    19141 ggtcgggctc ggactcgtcg gcttcgtcga cgacttcctg aagacccgca accagcgcag
    19201 cctcggcctc ggcggctggg cgaagatcgc cggccaggtc atcgtcgccg cggccttcgc
    19261 ggtgatcgcg atcatggtcc gcgactccaa cgggctcacc cccgcgtcca cctcgatctc
    19321 gttcatccgc gacctgccgt tcgacttcgc ctccctcggc tggatcggca tcggcctgtt
    19381 cgtgctgtgg atctgcatca tcgtcaccag cacgtcgaac ggcgtgaacg tcgccgacgg
    19441 gctcgacgga ctcgcgaccg ggtcctcgat cctcgcgatc ggctcctacg tcatcatcgg
    19501 gttctggcag tcgaaccagt ggtgcttcga ccagcacctc aaccccgagg tcgtcgacaa
    19561 gtgctaccag gtgagcgacc cgttcgacct ggccatcatc gcggcggccg tctccggtgc
    19621 cctggtgggc ttcctctggt ggaacacctc gccggcgcag atcttcatgg gcgacaccgg
    19681 ctcgctcggc ctcggcggcg cgctcgcggc cctggcgatc ctcacccgca ccgagctgct
    19741 ggtcatcctc atcggcggcc tgttcgtcat cgtgaccggc tcggtcatcc tccagcggat
    19801 ctacttcaag ctgacccggg gcaagcgcat cttcctgatg agcccgctcc accaccactt
    19861 cgagctcaag ggctgggccg agatcaccgt cgtggtccgg ttctggatca tcgccggcat
    19921 cttcgtcgcc gccggagtcg ggctcttcta cctggaatgg ctgtcgctgg catgaccgat
    19981 cccgcccgtc ccgactccct ccgcagctgg cactcggact ggcgcggcct gcgcgtcgcc
    20041 gtgctgggcc tgggcgtcac cgggttctcg gtggccgaca ccctgaccga gctcggctcc
    20101 gaggtgctgg tcctcgccga ccgcgccgac gaggagcgcg agcgcctgct cgaggtgatc
    20161 ggcgcccgcc tgcaccgggc cgaccgcctc gactccgctc cggaggagct gcacgcgttc
    20221 gcaccggagc tggtcgtggt gtcgcccggc ttccggccga cgcacccgat cctcgtgtgg
    20281 gcggcggagt ccgggatccc cgtgtggggc gacgtcgagc tcgcctggcg cgtccgcgac
    20341 aaggtcgtgc gcgccgacgg cactccggcg gaatgggtgg ccgtcaccgg caccaacggg
    20401 aagaccacga ccgtccagct cacggcgacg atgctcgtgg ccggcggcct ccgcgccgcc
    20461 ccctgcggca acatcggcgt gcccgtgctc gacgcggtcc gcgacccgca gggcttcgac
    20521 gtcctcgtcg tggagctctc gagctaccag ctgcactacc tgggcgcgat cgagccgatc
    20581 gcgagcgtgt gcctcaacat cgccgacgac cacctcgact ggcacggttc gttcgacgcc
    20641 taccgcgcag ccaagggcaa ggtctacgcc ggcacccgcg tcgcctgcgt gtacaaccgc
    20701 gccgacgcgg cgaccgagca gatggtgctc gacgccgagg tggtggaggg cgcccgggcg
    20761 atcgggttcg gcctcggcgt gcccggcccg agcgacttcg ggatcgtcga cggcatcctc
    20821 tgcgaccgcg ccttcctcga ggaccgccgc accagtgccc tcgagatcac caccgtggac
    20881 gagctcgccg ctcggaacct cgccgctccg cacatcgtcc agaacgtgct cgccgcggca
    20941 gcgctctccc gagcgtgcgg gatcgaggtc acggccgtcc gcaccgcgct ggcgtccttc
    21001 gagctcgacg cccaccgcat ccaggtcgtc gccgagcacg acggggtgac ctgggtgaac
    21061 gactccaagg ccacgaaccc gcacgccgcc gacgcctcgc t
//
