LOCUS       NZ_PSVY01000001        22502 bp    DNA     linear   CON 18-SEP-2024
DEFINITION  Rathayibacter sp. AY1D1 AY1D1_1, whole genome shotgun sequence.
ACCESSION   NZ_PSVY01000001
VERSION     NZ_PSVY01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Rathayibacter sp. AY1D1
  ORGANISM  Rathayibacter sp. AY1D1
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Microbacteriaceae; Rathayibacter.
REFERENCE   1  (bases 1 to 358798)
  AUTHORS   Davis,E.W. II, Tabima,J.F., Weisberg,A.J., Lopes,L.D., Wiseman,M.S.,
            Wiseman,M.S., Pupko,T., Belcher,M.S., Sechler,A.J., Tancos,M.A.,
            Schroeder,B.K., Murray,T.D., Luster,D.G., Schneider,W.L., Rogers,E.,
            Andreote,F.D., Grunwald,N.J., Putnam,M.L. and Chang,J.H.
  TITLE     Bacteriophage NCPPB3778 and a type I-E CRISPR drive the evolution of
            the US Biological Select Agent, Rathayibacter toxicus
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 358798)
  AUTHORS   Davis,E.W. II, Tabima,J.F., Weisberg,A.J., Lopes,L.D., Wiseman,M.S.,
            Wiseman,M.S., Pupko,T., Belcher,M.S., Sechler,A.J., Tancos,M.A.,
            Schroeder,B.K., Murray,T.D., Luster,D.G., Schneider,W.L., Rogers,E.,
            Andreote,F.D., Grunwald,N.J., Putnam,M.L. and Chang,J.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2018) Botany & Plant Pathology, Oregon State
            University, 2082 Cordley Hall, Corvallis, OR 97331, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-NOV-2017
            Assembly Method                   :: SPAdes v. 3.11.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 161.699x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002932635.1-RS_2024_09_18
            Annotation Date                   :: 09/18/2024 02:01:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,548
            CDSs (total)                      :: 3,497
            Genes (coding)                    :: 3,463
            CDSs (with protein)               :: 3,463
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 34
            CDSs (without protein)            :: 34
            Pseudo Genes (ambiguous residues) :: 0 of 34
            Pseudo Genes (frameshifted)       :: 6 of 34
            Pseudo Genes (incomplete)         :: 27 of 34
            Pseudo Genes (internal stop)      :: 3 of 34
            Pseudo Genes (multiple problems)  :: 2 of 34
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:54:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 20363
            Orig. end                         :: 42865
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PSVY01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22502
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22502
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22502
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12502](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12502)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(91..104)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.27"
                     /tool="antismash"
     misc_feature    complement(506..524)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.83"
                     /tool="antismash"
     misc_feature    603..618
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.69"
                     /tool="antismash"
     gene            806..1351
                     /locus_tag="C5C56_RS17425"
     CDS             806..1351
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C5C56_RS17425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_146086428.1"
                     /transl_table=11
                     /translation="MGTEAESPRRASATGHDVDVDAFGLPLDAFGNTVQPDFFQILGRL
                     VAVNGQIEYLQDRFDHLPNEETSGVRKVEQFERRSEAGRADRNAVVHSRWVFGAHADPA
                     VVVGIRYKTRRQTSGTVAAVSIIDVSGSERKQDVVEHTVESLRGVLRRDVATMRIGQLA
                     LSEIMLRYAASRIESAIY"
     gene            complement(1525..1944)
                     /locus_tag="C5C56_RS17430"
     CDS             complement(1525..1944)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C5C56_RS17430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_146086429.1"
                     /transl_table=11
                     /translation="MPVANSTKLLLISRAAVWKTPTFDPDDYLRNFVLDYMQARELANP
                     NSRLVQHRSPTGKYKGAPFVTKKSILEANSGTAKELNMSVTEEEAEVFHKYREAAGKKS
                     EPLSHAAIAPVAGTPLPDWDDLLQKVLDVSRGSAG"
     misc_feature    complement(1918..1920)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(1942..1956)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.34"
                     /tool="antismash"
     misc_feature    complement(1956..1969)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.22"
                     /tool="antismash"
     gene            complement(1984..2532)
                     /locus_tag="C5C56_RS17435"
     CDS             complement(1984..2532)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C5C56_RS17435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_146086430.1"
                     /transl_table=11
                     /translation="MTTTNGGGVRVSEYFLLCLTQPSLEFLDVHIDADTRVFVDPHAFR
                     FLKTDWAIESVALLENFYDRLLEAVRRRDRVAATALLQYSGESNEAHLGLSSHESRGSG
                     VGTGLADDLYDALVGSRAVLTGTAEDLKETALFVPGILHDRISDMTNNVVRSQLIEFTQ
                     ETSRRHRIPLTASVASGPM"
     gene            complement(2529..2804)
                     /locus_tag="C5C56_RS00100"
                     /old_locus_tag="C5C56_00100"
     CDS             complement(2529..2804)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024776.5"
                     /locus_tag="C5C56_RS00100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00100"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_146086431.1"
                     /transl_table=11
                     /translation="MNELVELNNNGAQSTELMLQYGLSKSSVLSILRKHGGQLRRKGLT
                     TDQEALALRLREQGLSYRRIAERLGAAKSTVQLWLKQQQARPQSVG"
     gene            complement(3029..3655)
                     /locus_tag="C5C56_RS00105"
                     /old_locus_tag="C5C56_00105"
     CDS             complement(3029..3655)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C5C56_RS00105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C5C56_00105"
                     /product="uracil-DNA glycosylase"
                     /protein_id="WP_104318937.1"
                     /transl_table=11
                     /translation="MPRSMADLSFRRAQWEQRYAPHVAPVNRWVDELRNPYGRGWLPYV
                     APLHGGMEARVLSVLRDPGPATQDGIGSGFLCTENDDPTAELMAGLMDEVGLAPVDLLP
                     WNAYPWYINQAPNAEQLDAGVETVLHLLALAPDVEVVLLQGGDADHGWRRLLRRHPAIE
                     RERGLTVIRTFHPSRQALWARDPAEREARSARRREAFAEVAAALR"
     gene            3812..5788
                     /locus_tag="C5C56_RS00110"
                     /old_locus_tag="C5C56_00110"
     CDS             3812..5788
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013583247.1"
                     /locus_tag="C5C56_RS00110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00110"
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="WP_104319012.1"
                     /transl_table=11
                     /translation="MTDSAPLARWWREPWWARLTLLAILIGSAVLTGWNLARGGDAVFY
                     EAAARSMSESWHALAFGAFDPAATVTLDKLAGFAVPQALSIRLFGMSTSSIALPQLLEG
                     LITVAACSVVGLRWGGRGLGLVAAAAAASTPIFVSMFGHPMEDGLLTAALAVALMWWQR
                     AVLTERWWPLLLAGAFIGIGFQAKMMQAWFVLPALVVATLVGVRGWRRALAWAGGLLAV
                     AVGASVAWMVAMQAVPAGDRPYIDGSTGNDVFAMVFGFNGLDRLIPGAVPGAVVASAHV
                     ATMGGAAGSSPAKLLLAQYATQVGWLYPAALAGLVLGAVRWWPRRGRRGGARGAFALLV
                     CLAVWLVTAAGVLSVATVPHMAYVAAIGVQLALLAALGWAEAVRLLASTRVVARLVLPL
                     ILVAQTAWSAVLAVGGQLPAVLGLPFAALAGAGLVVVAVAARWSRGGAAASRGAARHRS
                     IALAAAVVILAGPIAFSLQVLDASLDGSGGDALVGLRFPQRAETSAPFAVSSPDAVGGH
                     DSMTADETALVAAARAAGGGVDGAPLFLTDSWAISAPIITATGASVLTDGGYSGQARVF
                     TEQDVAGMIAAGRTPLLVLKNSAPPTESVRKAVVADGCIQLQEWGPAATESGEHASAVT
                     GFSLWRCVAMPHGSAGGVSGAGQ"
     gene            complement(5864..7465)
                     /locus_tag="C5C56_RS00115"
                     /old_locus_tag="C5C56_00115"
     CDS             complement(5864..7465)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012546.5"
                     /locus_tag="C5C56_RS00115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00115"
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="WP_146086432.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 8.5e-17, bitscore:
                     55.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHTLVIAPQESLVLSPGAAAFALVSDQDGDEHHRIRVAVATRSG
                     AVEIVQDERPVSPRIRSFSDGFLWIRRNDAGRPWQAVWWHRSLTTPHVLLEEPDQARRL
                     DLRSVAGAIAVLASRGARDSRYWVLTGEESSPPTCRRLDLGTENADVSACRGGLAVLYR
                     RHGVVRMTGSTRPLEVPVPKALQAEHLQEAQGELFVLGRSSGRRAVWLPGGGADALWLA
                     PAAGTLVPAVDPITRHPIMLVSSPAHRAHCVTPVPGKALATEVTERMKVTSLTAPSRDG
                     TLVPLTLMTPDGADSCPVVVHVYGAYGISLEGPFDPFTDDLLARGAAIAYCHFRGGGEN
                     GPEWHRQATGLGRERPIEDLLACLALLRELPGIDSHRLLLTAASAGALVAATVCLRRPA
                     ELRGLHLVHPFLDPVGALDDRSAAAAASDREEFGDPDWILASGLSPLATIATMVGRSRP
                     LPGAWIRAGLRDARVDASAIAEFASAYRAVAERDDPAHVVLRATSGGHLSGLTPEESHQ
                     ENVLAHAWTLDLLGLA"
     gene            complement(7614..9014)
                     /locus_tag="C5C56_RS00120"
                     /old_locus_tag="C5C56_00120"
     CDS             complement(7614..9014)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014717.5"
                     /locus_tag="C5C56_RS00120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00120"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_104318939.1"
                     /transl_table=11
                     /translation="MSRYVVRLFADEWRRWSPAIAVVALMATLIGLCVQQFASTGDPAF
                     TAAVTEAGVALGEFRILSITIYTVVALVGWVALTIVGRASVLATGRTHALWLLLGASRA
                     QVFVVTLLVLGIVSLLGAGIGALLSTLLAFWAVPAFNGAVSSEVDLPSFSLAPWAPVVT
                     LALGTLTALAGGVLPARRAARTPPSAALREVRSGRPGTAMRAVRIGCGIALLLIASGLV
                     TASASARELGATGPAPMFNLAVDVGGSVLVAVYLLCPEVIALVFRALHALSARSGLVVA
                     ALGIRAAAARVQVSTATIAPLTAGLGAIAVLLCAVESAVAMTTAVRPGTRADLTDVLTI
                     VAVVAVSMLATSATVVALSAQNREREIALLQAAGLQRRQIIGLVVSESLAMSLAASTAA
                     AAPVAATGAVCWLVSRAALGEGKVIWPVPSVVLGLIGSWIVLSLILLIPAQARLRRPPG
                     PRLREQGV"
     misc_feature    complement(8986..9001)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.04"
                     /tool="antismash"
     gene            complement(9018..9740)
                     /locus_tag="C5C56_RS00125"
                     /old_locus_tag="C5C56_00125"
     CDS             complement(9018..9740)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019135735.1"
                     /locus_tag="C5C56_RS00125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00125"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_104225415.1"
                     /transl_table=11
                     /translation="MIPTLQARAVEQVITVGRQRTTVLRGCDIDLEGGGLTAVVGRSGS
                     GKSSLLMCLSGLDRPTSGVVEVNGRDVNRLSAADRARMLRAQIGFVFQQYNLVPFLDVE
                     ENIALPFRLDRSPVPHDLIGGLVESFGLRDRRRAPARTLSGGEQQRTALCRALARRPGI
                     VFADEPTGALDSQSSRVVLSTLRTMADEGQMIVMVTHDLDAAALADTVVVMHDGRTVRT
                     TGRCTSHELLSILEEAGA"
     gene            complement(9833..9964)
                     /locus_tag="C5C56_RS18210"
     CDS             complement(9833..9964)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C5C56_RS18210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_258059251.1"
                     /transl_table=11
                     /translation="MNRILDFQTLEGEADAHDAARVSTFSVISPCPGWPSSITWGNC"
     CDS_motif       complement(9902..9964)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNRILDFQTLEGEADAHDAAR"
                     /locus_tag="C5C56_RS18210_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9833..9901)
                     /prepeptide="core"
                     /locus_tag="C5C56_RS18210_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="4.60"
                     /molecular_weight="2199.5"
                     /monoisotopic_mass="2198.1"
                     /core_sequence="VSTFSVISPCPGWPSSITWGNC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNRILDFQTLEGEADAHDAAR"
                     /leader_location="[9901:9964](-)"
                     /alternative_weights="2217.5"
                     /alternative_weights="2235.5"
                     /alternative_weights="2253.5"
                     /alternative_weights="2271.6"
                     /alternative_weights="2289.6"
     gene            complement(10001..12502)
                     /gene="lanKC"
                     /locus_tag="C5C56_RS00130"
                     /old_locus_tag="C5C56_00130"
     CDS             complement(10001..12502)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="C5C56_RS00130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00130"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_104318940.1"
                     /sec_met_domain="micKC (E-value: 4.2e-144, bitscore: 475.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.3e-09, bitscore: 32.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 3.1e-07, bitscore: 24.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-07, bitscore:
                     24.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLDLEYLRYCRPGNPFYAVAEEGDDIDGDAFDVASFAPEDWQVR
                     ESRPWRNWMPDGCLLPRQGWKLHLSSTLDDAEKVLAAAARYCFASRLPFKHLSTTSHLL
                     MQNGKYADRAGAGKFITVYPGSDDEFARALEDLDVRLRGFRGPYVLSDRRWKSGPVHFR
                     YGAFVPSETESGFVSTVLDPDGNEVEDVRRPTFTPPPWASLPESVTVGAENEEEVAFGF
                     TMLSALHFSNGGGVYLAEATTDEFVPIGTIVVLKEARPHAGLDADGVDAVTRLAHEEEV
                     LVDLQSLDCVPVFYGSFTAWEHRYLVMEYIEGNDLKREWMTRTPLLRPAPWRVGDPAYT
                     SWLTTTVARLDAALASVHRAGWLLGDIHPKNVIMRNGTHPCFLDFEFAHRMDPEWRCRQ
                     GAPGYEPLEGLKGTEADEWSLGILELDLLFPQATIADQGNVAKIEQLLRAAADDLAVPP
                     AVLRSIRTSTLDVLPASGQRSIDEDVGRLAALSDDQLRGQIARGVASVLQWTDDSPVVP
                     GDIPVLARDSADHRAGFPYGAAGVVAVLGRSGDVDLEAADHWLAAHVAQVRSRGLCGLE
                     GIRYAARQAGLARTLEVLDRRPSAAPSGPTLWSGWAGAGLAELADGGDPSEAAHHLTTL
                     LDEDVRGASVGLLHGWSAAAILFARLHEATGDDLYITLAIRAVDADLARCANTRNNTLE
                     FDEGWRTLPYLGIGSTGPGLAILELRRVTGEELFADPLASIDAAASYQQCAQASLAHGL
                     SGFLVYLRRRVLHRPSAKLEEVLRSHVRSLRLHAVLDDTGVFFRGNQNLRLSSDYLTGS
                     LGVLAALDELETGRSALPFGL"
     misc_feature    complement(10868..10870)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12638..12653)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     misc_feature    12674..12689
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.35"
                     /tool="antismash"
     gene            12690..14000
                     /locus_tag="C5C56_RS00135"
                     /old_locus_tag="C5C56_00135"
     CDS             12690..14000
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.5"
                     /locus_tag="C5C56_RS00135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00135"
                     /product="sensor histidine kinase"
                     /protein_id="WP_104222531.1"
                     /transl_table=11
                     /translation="MGSTPETAAEISAPSAAGHERVAVAPSLSSTVDRTVIALQAIALC
                     CLVLAGILGVVDSAQRGTGAAVAVTWLALVPVIAGLWAVRPRLIRAGHGVAVTTVSIVA
                     ATPVVVFGRLDFTIPVLLLVVAFAVVDVSLRAGAHAMIWIASVGLALHVGGAVGSGRAL
                     LSGVLDGLLNVVPVAVLMCFGIALGLSLRGFESERSADQRVIRRLHRASETEKELLLSD
                     ERARSARELHDGLGYKLTLVSMSLELADRLRSADAEQAWAEVRTARSTSSEALADMRMW
                     VRALSPFRDAGARGLAALELIAESFRGTGVTVDVVGDEASDRVLTSDDETALVVYRGVQ
                     EGLTNALRHGAARRVRIDIETDDVRLELSLLSDIGAGRSNGISDGEPVLGFGLRGLDDR
                     ATARGGRLTARRIGDRFLLRLSIPLGGADGERESRAS"
     gene            14030..14644
                     /locus_tag="C5C56_RS00140"
                     /old_locus_tag="C5C56_00140"
     CDS             14030..14644
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010849376.1"
                     /locus_tag="C5C56_RS00140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00140"
                     /product="response regulator transcription factor"
                     /protein_id="WP_258063291.1"
                     /transl_table=11
                     /translation="MEDQQMIRRGLVMLLSTVEGVVVSAQAENGQAALHILRTTEVDVV
                     VTDARMPVMGGVELAAECAQLHPRLPVLLLTTFDDDALVQAALSAGASGFLLKDTSVEG
                     LVVALDAVIAGGMVIDPRVARPAVQPGRTGESPLTLLTRSERVVAELVAEGRNNREIAA
                     ALVLAEGTVKNHVSALLRKLGLRDRTALALTLYKGFRPDGA"
     gene            14717..16192
                     /locus_tag="C5C56_RS00145"
                     /old_locus_tag="C5C56_00145"
     CDS             14717..16192
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018170489.1"
                     /locus_tag="C5C56_RS00145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00145"
                     /product="DUF3375 domain-containing protein"
                     /protein_id="WP_104269178.1"
                     /transl_table=11
                     /translation="MSNSRAEAAYLRSLGAFRTPTLDLLHGRYAPFVVAALSLVFTVDR
                     QVVAVADAHAEVGELLEELRSAGYDEVERALPSGTAREVCRYWVRVGWLVPQIEGEAEV
                     YRLSAHAVSALEITGRTGGGRTRVSNSRVRTLLEAVERLAADVDPDPEARLSRLREERA
                     RLDAEIAALEEGAGLEPADDEQLLEEAENVVHLARELPADFARVAESIKAMQRDVVADL
                     RRDVRPTGEVLREYLERGQHVMQATSEGRAFAGALRLLGDPERIDALADQLHTVLVQPF
                     SRLMDPAQRAELAAIGRRVELGVQEVLTAQRRASHVITGQVRTHDPARDRQVDELLRDV
                     MAGLQEWTGGISPDAPVAPLRHLPVAGIGHLRQTLGDVRPAGGPAPLAGDDGDAEFVGD
                     DSRAWGGPRYAELEAYVAELGDEFDLADAFSAAPEDTRRPVDLLGLLEIAHRTGLVDRE
                     GYSVVSTRRPDGTVRRFAFGSVTARTEEETDDE"
     gene            16185..17072
                     /locus_tag="C5C56_RS00150"
                     /old_locus_tag="C5C56_00150"
     CDS             16185..17072
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013117259.1"
                     /locus_tag="C5C56_RS00150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00150"
                     /product="DUF4194 domain-containing protein"
                     /protein_id="WP_104288282.1"
                     /transl_table=11
                     /translation="MSDTLATDGTAADPFIAPVSMEEDPDELFPGDRGVLDTEVRRVLV
                     HVLQRRFLLADRHREQWAVLQEHRQLIESRLNDLFVRLVVDHERGVAYKQQVRSDEVEM
                     PVLLRDLPYTRAETLVLVHLRTVHQRESAAGEASARVDVEEVEQTVLSYFADAERDTAR
                     RQRMVRKALERLGRDGIVDEESAGRYRISSIVEIVLSAPKLRELSDWLRGRAGEDASSV
                     VAEAAPAEEPGSDDPEEADDDALEDDGLDEDADPPTDGVLPGVDVADDEPLDDEPLDDE
                     PTDDDTPDPEDDPR"
     gene            17069..20410
                     /locus_tag="C5C56_RS00155"
                     /old_locus_tag="C5C56_00155"
     CDS             17069..20410
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013583250.1"
                     /locus_tag="C5C56_RS00155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00155"
                     /product="ATP-binding protein"
                     /protein_id="WP_104318941.1"
                     /transl_table=11
                     /translation="MTMLDTLFGLIPAASRGQQWLAEDLQLVNWGGYDGAHRVRFSPGA
                     TLLCGGSGSGKSTLMDAYIALMMPHTTPFNGASNGGVTGRPRGEDQRNILSYARGKLDE
                     SRTDEGTTMRVLRGDGVDTWTAVAMTWVDHDGSRFSAVRAWYVPAGSRVLEETVRIRAS
                     AEGPVDLAALDRAAAHRFSDASLRAAGLDPLGTDREFSARLHAVLGIGAAGAGSKAMSL
                     LARIQAGQQITTVDDLYKRLVLEEPETLASADAVVAHFDELESTRQRMLTARQQVAALE
                     PLRGLRLRIAASAERVRLIDALGEFDAPVSPAALWRAEQRLGLLRDVEVELRERTRAVD
                     AVLREKRALAEAAESERDGLAEVLRASGGDRLETAQRELREVERRLGAARENRARLEED
                     LRALGEPETTRERFEAVLARAASAADAKRSTRAAWSDAVAERKAAARDLAELEAEQRSA
                     SDRRDSIPRPLHEARERVAEAASLTADDLPFVGELVEVRAEFEPWREAFTLALGGFATT
                     LMIDSAHLDRFRRAIDSLRLPVRLRYEGVETGLEEVRGLDPQTLPGRLDYRATAFTGWL
                     QDRLEDRFGYVCVDSAAELGRHRLALTLTGQLSQGQRGAHGGHGAANVLGFSNTGRLRE
                     LNALVEAARARSAAAVSAASAAEEALDALDDRMTRHARLALVSWETVDVESLLAEQERW
                     EAVGAEAAEANPELAGLQEQIDGLRGRLERLRQEIARAGVERERIEAEWAVVVDDVDAS
                     QAVLDAAEQAGRELDDDQRAFLDARFTLTEAAASGSASDVLVRFDAALATAAQRLAEDR
                     RSAAEAHEQQRESAGRIMAGFLDRWPNPNLLADPEASAGDFERLLDALETSGLHRLETE
                     WRDSLLTLSGNDLTSFDSTLGRSLREIRERIEPINVIMQDLPFYDDGHRLQITTRENQS
                     EVRRRFRRELREVRAQIQAVSAEEEREQVYRRMSRLIQRLRRTAPDFGDLVDVRNHVRV
                     SAERVDAVTRAHVALYDHIGEKSGGESQELIAFIVGAALRYQLGDAGADRPRYAPVFMD
                     EALIKADAHFTKRAIGAWRGLGFQLVIGAPNDKYSAIEPHVEVEYDILKDTRGRSWARP
                     KVGLAP"
     gene            complement(20407..21861)
                     /locus_tag="C5C56_RS00160"
                     /old_locus_tag="C5C56_00160"
     CDS             complement(20407..21861)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019137709.1"
                     /locus_tag="C5C56_RS00160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00160"
                     /product="amino acid permease"
                     /protein_id="WP_104225409.1"
                     /transl_table=11
                     /translation="MSLLRTKSVEQSIADTDEPEYKLKKSLTALDLTVFGVGVVIGAGI
                     FTLTGRAAHDIAGPAIVLSFVVAAFACALAAMCYAEFASTVPVSGSAYTFSYASLGELF
                     AWIIGWDLILELFLGASVVAQGWSAYLGSLLQQLGVTLPPALTYGGVVDVPAILLVLVL
                     GALMTFGIKESLRVNLVLVAIKLFIVLFVIIAGLQFVNTANYTPFVPAAEPSQSASGLT
                     QPLLQFLSGIEPATFGVGGIIAGASLVFFAYIGFDVVATTAEETRRPQRDLPIGIIASL
                     IICTVLYCAVALVVTGMVPYRELDPSAALANAFAYHGQTWMATVISAGAVAGLTTVVLT
                     LLIGATRIIFAMARDGLLPRRLATVHPRLRTPWFTSVVVTIVVALLAGLTPIGVLEEMV
                     NIGTLSAFVLVSVGVVVLRRKRPDLKRGFRVPLNPWLPLLSALICTYLMLNLSIETWLR
                     FLIWLAVGFAIYFAYSRSHAKIGTQP"
     gene            21970..22323
                     /locus_tag="C5C56_RS00165"
                     /old_locus_tag="C5C56_00165"
     CDS             21970..22323
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013586165.1"
                     /locus_tag="C5C56_RS00165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C5C56_00165"
                     /product="DUF2200 domain-containing protein"
                     /protein_id="WP_104247170.1"
                     /transl_table=11
                     /translation="MSRIFSVAFADVHPLYVAKAERKGRTREEVDEAVRWLTGFSDEEL
                     ARHLESRTTFEEFFAAARLPPEASAITGVICGVRVETIEDPLMQRIRYLDKLIDEIAKG
                     RPMAKVLRAPAAG"
ORIGIN
        1 cacgcggaac gctcctccga ttcccgcgag gtcgacgacc gcactatgga gcggattgaa
       61 tctcgacttc ggattggaaa tgagggtgtg tgcgtgggca tgcgcgtcaa atccctgggc
      121 cagagactcc agctgtccga tgaaaaagtc cagtccgccg cgcttcgaga acgggtgcga
      181 cgccagtcga gcaagcttct tcgcgaggct gtcaaacagg ggaaggtttg aaggcttgcc
      241 cagcgaagct cccgcgccga cgaagaacac gagctcgccg cgctcatgag catcgaggat
      301 ctcgtcaggc agctggacct cgccggtgat ccacatcagg tcacgacctc ggtgtcgtcg
      361 ttgagcatgt tcaccgacgc acctcgcggg cgccgcggaa gaccgtgaaa cagctcgcca
      421 gggtgggcct gcccaggcgc gctgtagcag tccggactaa cgccacgtcg tctccctcgt
      481 tcgctcttgc tgagcgctcc gacgtcgctc actgaataca agtgtcccgc agcccagcaa
      541 cggtgcgcga gcccctgatc tcgtgccgaa gttggcgcga atcgatcgaa gacccccgaa
      601 atgacaacac ctgtaatcaa gctagttccg aacgcctgct gccagtttgt agccttgccg
      661 ccaacctcgc gatgatccgc tccgtcgggt agcgcagtct tgcgcaccct tctccgacta
      721 cgtctccgcc cggtacgcag tgtgctggcc gcatcaggcg aacgcgtcac tgggcggggg
      781 cgcgatcttg ggtcacaatc aatgcatggg tactgaagcg gagagcccga ggcgggcgtc
      841 ggcgacgggg cacgacgttg atgtcgatgc gttcgggctg ccgctcgatg cgttcggcaa
      901 caccgtgcag cctgacttct tccagatact gggacgactt gtagccgtga atggtcaaat
      961 cgagtatctg caagaccgct tcgaccatct tcctaacgag gaaacgagcg gggtcaggaa
     1021 ggtcgagcag tttgaacgaa gaagcgaggc aggacgcgct gatcgcaatg cggtcgtcca
     1081 ctcacggtgg gtcttcggag cccacgcgga tccggccgtc gtcgtcggga tccgctacaa
     1141 gacgagaagg caaacatccg ggacggtagc ggcagtttcg atcatcgatg tttcgggcag
     1201 cgaacgcaag caggatgtgg tagagcacac cgtcgagtcg ctccgcgggg ttctcagacg
     1261 tgacgtggcg acaatgcgca tcggtcagct tgcgctcagc gaaattatgc tgaggtatgc
     1321 agccagccga atagagtcgg ccatctactg aacaccgagg gagggttttg acattgcctt
     1381 atttctgcct cgcatcttga ccacatcgag cggagtcgat aagggcaacg tcagttgtaa
     1441 gaagcgctct cgcaagtact tgagaagagt cgcctcaccg cttttgaggg cctctactag
     1501 cacttcagat cctcgtcgtc taactcatcc ggcagaccca cgcgaaacat ccagcacctt
     1561 ctgcaaaagg tcgtcccagt cgggcaatgg cgtacccgct acaggtgcga tcgcggcgtg
     1621 actaagcggc tccgacttct tgcccgccgc ctcccggtac ttgtgaaaga cttcggcttc
     1681 ttcttccgtt acgctcatat tcagctcttt tgcggtgccg gaatttgctt cgaggatcga
     1741 cttcttcgtg acaaagggag cacctttgta tttcccggtt ggggaacgat gctgaacgag
     1801 cctcgaattt gggttggcga gctctcgcgc ttgcatatag tcaagcacga aattccttag
     1861 gtagtcatcc ggatcgaacg tgggcgtttt ccaaacggct gcgcgtgaaa tcaatagtaa
     1921 ctttgtggag ttcgcgacag gcatttcctg aaagttgctt gtccatgcat gagtggttct
     1981 atctcacatt ggacctgatg cgacgcttgc agtgagtggt atcctgtgcc gacgagaagt
     2041 ctcttgtgta aattcaatca attgactgcg gacgacgttg tttgtcatgt ccgatattcg
     2101 gtcatgcaaa atgcccggga cgaagagagc cgtctctttg agatcctctg cggtgccggt
     2161 tagtaccgcg cgactaccta caagggcatc gtaaaggtcg tcggcaagcc cggtaccgac
     2221 gccgctccca cgcgactcgt gcgaggaaag tccaagatgc gcttcgttag actccccgga
     2281 gtattgcagc agtgctgtgg ccgccaccct gtcccgtcgg cgcactgctt cgaggaggcg
     2341 gtcgtaaaaa ttttcgagga gggccacgct ctcgattgcc cagtccgttt ttaggaaccg
     2401 gaacgcgtgc ggatcgacga agactctcgt gtcggcgtcg atgtgaacgt cgaggaactc
     2461 cagtgatggc tgagtcagac acaggaggaa gtattccgaa actctcacgc cgcctccgtt
     2521 ggttgtcgtc atccgactga ctgcgggcgg gcctgttgct gcttgagcca gagttgtacc
     2581 gtgctcttcg ctgcgccgag gcgctcggcg atccgccgat atgacaggcc ttgctctcgg
     2641 agccgaaggg ccaaggcttc ctggtctgtc gtcagtccct ttcgccggag ctggcctccg
     2701 tgcttgcgaa ggatgctcag caccgagctc ttggacaggc cgtactggag catgagctct
     2761 gtcgactggg cgccgttgtt gttcaactcg acaagctcat tcatggctgc ttcaccgagc
     2821 cggacctcca cgttccggac tgagcgcgtt cctcttcgag ggtgacgccc tgctcgaccc
     2881 gcaagattct gcagctctcg cgttgtgatc tgtgtgtagc ggatgtttga gtagcgtcgt
     2941 acaaagtcga cggaaagccc tgatgagacc actggtcgtc gtcagggctt ccgtcgtttc
     3001 cgggcctcgt cgtgacgctg cggaccgctc accggagcgc tgcggcgacc tcggcgaagg
     3061 cctcgcgacg tcgagcggag cgcgcctccc gctcggcggg atcccgtgcc cagagcgcct
     3121 gtcgggacgg atggaaggtg cggatcaccg tgaggccgcg ctcgcgctcg atcgccgggt
     3181 gccgcctgag gaggcgccgc cagccgtgat cggcgtcgcc gccctgaagg aggaccacct
     3241 cgacgtcggg ggcgagcgcg agcagatgca ggacggtctc gacgccggcg tcgagctgct
     3301 cggcgttcgg cgcctggttg atgtaccagg ggtaggcgtt ccacggcagc aggtcgacgg
     3361 gggcgaggcc cacctcgtcc atcagcccgg ccatgagctc cgccgtcggg tcgtcgttct
     3421 cggtgcagag gaagccgctt ccgatgccgt cctgagtggc ggggccggga tcgcggagga
     3481 cgctgaggac gcgcgcctcc attccgccgt gcaggggcgc gacgtagggc agccagccgc
     3541 gtccgtaggg gttccgcagc tcgtcgaccc agcggttcac gggagccacg tgcggtgcgt
     3601 agcgctgctc ccactgggcg cggcggaagg agaggtcggc catggagcgg ggcatgtccg
     3661 caccctggag ggtgaccggg gcggcgcggc acccttcctg gtcgtcggcc gtgccggcgg
     3721 cgtccggact gagaggccgg agcggcctgc acggcgtctc cccgaccgcc cgcaagggcg
     3781 gcagcaggcc ggctccctag cgtcggtgga cgtgaccgac tccgctccgc tcgcccgctg
     3841 gtggcgggaa ccctggtggg cgcggctcac cctcctggcg atcctgatcg ggtcggcggt
     3901 gctcaccggg tggaatctcg cccggggcgg ggacgccgtc ttctacgagg cggcggcacg
     3961 gtcgatgtcg gagtcgtggc acgcgctggc gttcggagcc ttcgatcccg ccgccacggt
     4021 gacgctggac aagctggcgg ggttcgcggt gccgcaggcg ctgagcatcc gcctgttcgg
     4081 gatgtcgacg tcgtcgatcg cgctgccgca gctgctcgag gggctgatca ccgtcgcggc
     4141 gtgctcggtc gtcgggctcc gatggggcgg ccgggggctc gggctggtcg cggcggccgc
     4201 ggcggcgagc acgccgatct tcgtgtcgat gttcgggcac ccgatggagg acggcctgct
     4261 gacggcagcg ctcgccgtcg cgctgatgtg gtggcagcgc gcggtgctga cggagcggtg
     4321 gtggcctctc ctgttggccg gagcgttcat cgggatcggc ttccaggcga agatgatgca
     4381 ggcctggttc gtcctgcccg ccctcgtagt ggcgactctc gtcggggtgc gcgggtggcg
     4441 ccgagcgctc gcctgggcgg gcgggctcct ggccgtcgcg gtgggcgcct cggtggcgtg
     4501 gatggtcgcg atgcaggcgg tgccggcagg ggaccggccc tacatcgacg ggtcgacggg
     4561 gaacgacgtc ttcgcgatgg tgttcgggtt caacgggctc gaccggctga tcccgggagc
     4621 ggtgcccggc gccgtcgtcg cttccgccca cgtggcgacg atgggcggag cagcggggtc
     4681 ttcgccggcc aagctgctgc tggcgcagta cgcgacgcag gtcggctggc tgtatcccgc
     4741 ggcgctcgcc gggctggtgc tcggcgccgt gcgctggtgg ccgcggcggg ggaggcgggg
     4801 aggtgcccgc ggtgccttcg ccctcctggt ctgcctcgcg gtgtggctgg tgacagcggc
     4861 gggcgtgctc tcggtggcga cggtgccgca catggcgtac gtcgcggcga tcggagtgca
     4921 gctggcgctc ctcgcggcgc tgggctgggc ggaagcggtg cggctgctcg cgtcgacccg
     4981 ggtcgtcgcg cggctggtgc tgccgctcat cctcgtcgcg cagacggcgt ggagcgcggt
     5041 gctcgccgtg ggcgggcagc tgcccgcggt gctgggcctg ccgttcgcgg cgctcgccgg
     5101 agcagggctc gtcgtggtcg cggtggcggc ccggtggagt aggggcggtg cggcggcgag
     5161 cagaggcgcg gcccggcatc gttcgatcgc gctcgcagcg gccgtcgtga tcctggcagg
     5221 gccgatcgcg ttcagcctcc aggtgctcga cgcgtccctc gacgggtcgg gcggggacgc
     5281 gctcgtcggc ctgcgcttcc cgcagagggc cgagacctcg gctccgttcg cggtctcgtc
     5341 gccggacgcg gtcggcgggc acgactcgat gaccgccgac gagaccgcac tggtcgccgc
     5401 tgctcgtgcc gccggcggcg gggtggacgg agcgcccctg ttcctcaccg actcctgggc
     5461 gatctcggcg ccgatcatca cggcgaccgg cgcgagcgtg ctcaccgacg gcggctactc
     5521 cggccaggcg cgggtcttca ccgagcagga cgtcgccggg atgatcgcgg caggacgcac
     5581 gcctctgctg gttctgaaga actcggcgcc accgaccgag tcggtgcgga aggccgtggt
     5641 ggcggacgga tgcatacagc tgcaggagtg ggggccggcg gcgacggagt cgggagagca
     5701 cgcctccgcg gtcaccgggt tctcgttgtg gcggtgcgtg gcgatgccgc acggctcggc
     5761 gggcggggtg tcgggtgccg gccagtgacg ccgtagggca gttctcgcct ggacgagatc
     5821 ggctcccgcc ggaacgatcg ccctcgtcct tgcgctcgac gggtcaggcc aggccgagga
     5881 ggtcgagcgt ccaggcgtga gcgaggacgt tctcctggtg ggactcctcg ggcgtcagtc
     5941 cgctgaggtg accgcccgag gtcgcacgga ggacgacgtg cgcgggatcg tcgcgctcag
     6001 ccactgcccg gtaggcgctt gcgaattccg cgatcgccga cgcgtcgact cgggcatcgc
     6061 ggagaccggc tcgaatccac gcgcccggaa gcggtcggct ccgccccacc attgtggcga
     6121 tcgtcgcgag tggagagagc ccgctcgcga ggatccagtc agggtcaccg aactcctcac
     6181 ggtcggacgc cgccgcggct gcggagcgat catcgagcgc gccgacggga tcgaggaagg
     6241 gatgcacgag gtggaggcca cggagttctg cggggcgacg gaggcagacc gtcgcagcga
     6301 ccagcgcgcc cgcgctcgcc gcggtgagaa ggagccggtg cgagtcgatc cctggaagct
     6361 cacgaagcaa cgccaggcag gcgaggaggt cctcgatcgg gcgctcgcgg ccgaggccgg
     6421 tcgcctgccg atgccactcc gggccgttct ctccgccccc gcggaaatgg cagtaggcga
     6481 tcgcggctcc gcgcgcgagg aggtcgtccg tgaagggatc gaacggcccc tcgaggctga
     6541 tgccgtaggc gccgtagacg tggacgacga cgggacagct gtcggcgccg tcaggagtca
     6601 tcagggtgag cgggacgagg gtgccgtccc ggctcggcgc agtgagtgac gtgaccttca
     6661 tccgttctgt gacctcggtg gcgagtgcct tacccggtac aggggtgacg cagtgggcgc
     6721 ggtgagcagg ggaggagacg agcatgatcg ggtggcgggt gatcggatcg acggcgggaa
     6781 caagggtccc ggccgccggc gcgagccaga gcgcgtctgc cccgccgccg ggcagccaca
     6841 ccgctctcct gccggacgac cgtccgagta cgaagagctc accctgggcc tcctgcaggt
     6901 gctccgcctg aagggccttc ggaacgggaa cctcgagagg acgcgtcgag ccggtcatcc
     6961 ggacgactcc gtgccgtcga tacaggaccg cgaggccgcc cctgcaggcg gagacatccg
     7021 cgttctccgt gccgaggtcg aggcgacggc acgtcggggg actgctctcc tctccggtca
     7081 gcacccagta ccgggagtcg cgcgcccctc tcgatgcgag tacggcgatc gccccggcga
     7141 cgctgcgcag atcgagcctc cgagcctgat cgggctcttc gagcagcacg tggggagtcg
     7201 tcaggctgcg atgccaccag accgcctgcc agggccgacc cgcgtcgttc cgccttatcc
     7261 agaggaatcc gtccgagaac gatcggatgc gcggggagac ggggcgctcg tcctgaacga
     7321 tctcgacggc tccgctcctg gtcgcgacgg cgacgcggat gcggtgatgc tcatcaccgt
     7381 cctgatcgct cacaagtgcg aaagcggcgg cgcccggcga gagcaccaga gactcctgcg
     7441 gtgcgatgac gagggtgtgc tgcacggggc gcccgtcggg atcccggagg agcacctgcc
     7501 gggggcctgt cggctccgcg gctgcgctcg acggctgcag agctgcgaga tgtcgcagcc
     7561 gtccggcgat cgcagaaacc cgaggcggca gtgcgtcgcg acccgtgatc acgtcagaca
     7621 ccctgctcac gcaacctcgg tccaggggga cggcgaagcc gagcctgcgc gggaatcagg
     7681 aggatcagcg agagcacgat ccacgagccg atgaggccga gaacgacgct cgggaccggc
     7741 cagatcactt tcccttcgcc cagtgctgcg cgactgacga gccagcagac cgcgccggtg
     7801 gcggcgacgg gtgcggcagc tgctgtggaa gcggcgaggg acatcgcgag gctctcggag
     7861 acgacgagcc cgatgatctg tcggcgctgc aggcccgctg cctggagcag ggcgatctcg
     7921 cgctcgcggt tctgcgcaga gagagcgacg acagtggcgc tggtggcgag catcgacacg
     7981 gctacgactg cgacgatcgt cagaacatcg gtgagatcgg cgcgggtccc gggccggacc
     8041 gccgtcgtca tggcgacggc ggactccacc gcgcacagga gcacggcgat cgcccccagc
     8101 cctgccgtga gcggcgcgat cgtggcggtg ctgacctgca cccgggctgc tgccgcgcgg
     8161 attccgagag ccgcgacgac gagacccgat cgggcggaga gcgcgtgcag agcccggaag
     8221 acgagcgcga tcacctccgg gcagaggagg tagacggcca cgaggacgct gcctcctacg
     8281 tcgacggcca ggttgaacat cggcgccggt ccggtcgctc cgagttctcg agcagaggcg
     8341 gatgccgtga caaggccgga ggcgatgagg aggagggcga tgccgcagcc gatccgcacc
     8401 gcgcgcatcg ccgtacccgg tcgaccgctc ctgacttcac gcagcgcggc gctcggcggc
     8461 gtgcgggcgg cgcggcgcgc gggcaggact ccgcccgcca gagcggtgag cgtgccgagc
     8521 gccagcgtga ccaccggagc ccagggcgcg agcgagaagc tcggaagatc gacctcggac
     8581 gagacggcac cgttgaatgc gggaaccgcc cagaacgcca gcagtgtcga gaggagcgct
     8641 ccgatgccgg cgccgaggag actcacgatg ccgagcacga ggagagtgac gacgaacacc
     8701 tgggctcggg aggcgcccag caggagccag agcgcgtgcg tgcgtcctgt ggccagaacg
     8761 ctcgctcggc cgacgatcgt cagggcgacc cagccgacga gcgccacgac agtgtagatc
     8821 gtgatcgaga ggatccggaa ctccccgagc gcgacgccgg cctccgtgac agcggcggtg
     8881 aatgcggggt cgccggtcga ggcgaactgc tgaacgcaca acccgatcag cgtcgccatc
     8941 agggcgacca cagcgatcgc gggagaccat cggcgccact cgtcggcgaa caggcgtacg
     9001 acgtaacggg acacgagtca ggccccggcc tcttcgagga tgctcagcag ctcatggctg
     9061 gtgcagcgtc cggtcgtccg cacggtccga ccatcgtgca tcaccacgac cgtgtccgcg
     9121 agggctgcgg cgtcgagatc gtgcgtgacc atcacgatca tctggccctc gtccgccatc
     9181 gtcctcagag tcgacaggac gacccgcgag ctctgcgagt cgagggcgcc ggtcggctcg
     9241 tcggcgaaga cgatgccggg ccgccgtgca agggcgcggc agagagcggt cctctgctgc
     9301 tcacctcccg agagcgttcg cgccggcgca cggcgccggt cgcgcaggcc gaacgattcc
     9361 acgagtccac cgatcaggtc gtgcggcacg ggtgatcggt cgagcctgaa ggggagcgcg
     9421 atgttctcct cgacatcgag gaagggcacg aggttgtact gctggaacac gaacccgatc
     9481 tgggcgcgga gcatgcgagc gcgatcggcc gctgacagcc tgttcacgtc ccggccgttg
     9541 acctcgacga cgccggacgt cggccggtcc agtccgctga ggcacatcag gagagaggac
     9601 ttgccggagc cggagcggcc gacgacagcg gtgagcccgc ccccttccag atcgatgtcg
     9661 cagccccgca ggacggtcgt ccgctgccgg cctacggtga tgacctgctc gacggctcga
     9721 gcctggaggg tggggatcat gagcgtttct cctcgacgaa ggtggggacg tcttactcgt
     9781 gagacgcccg cgatccacgt catgctggat cgcgggcgcc cggtagcgac tatcagcagt
     9841 tgccccacgt gatagagctg ggccagcccg ggcacggcga gatgacgctg aaggtgctga
     9901 cgcgcgcggc gtcgtgcgcg tcggcctcac cttcgagggt ctggaaatcg aggatccggt
     9961 tcatgtgatc acctcctctc ctcgtctcgg gccgactcgg tcagagtccg aacggcaggg
    10021 cggagcgtcc ggtctcgagc tcgtcgagcg ctgcgagcac tccgagcgag ccggtcaggt
    10081 agtccgacga gagtcggagg ttctggttgc cgcggaagaa gacgccggtg tcgtcgagca
    10141 cggcgtgcag gcgcagcgac cggacgtgcg agcggaggac ctcctcgagt ttcgcgctcg
    10201 ggcggtgcag tacgcggcgg cggaggtaga cgaggaatcc ggacagaccg tgggcgagtg
    10261 aggcctgcgc gcactgctgg taggacgcgg cggcgtcgat ggacgcgagg ggatcggcga
    10321 agagctcctc gcccgtgacc cgccgcagct ccaggatcgc caggccgggc ccggtcgagc
    10381 cgatccccag gtaaggaaga gtcctccatc cttcatcgaa ctcgagagtg ttgttccggg
    10441 tgttcgcaca gcgcgccaga tcggcgtcga cggctcgtat cgcgagcgtg atgtacaagt
    10501 cgtcgccagt ggcttcgtgg agtcgggcga acaggatcgc ggccgcagac catccgtgca
    10561 ggaggccgac ggaggctcct cggacgtcct catcgagcag cgtggtgaga tggtgggccg
    10621 cctccgacgg gtcccctccg tctgcgagct cggcgagccc tgcaccggcc caccccgacc
    10681 acagcgtcgg acctgaaggg gcggccgagg gcctgcggtc gagcacctcg agtgtgcgcg
    10741 cgagtcctgc ctggcgagcc gcgtagcgaa ttccctcgag tccgcagaga ccacgcgacc
    10801 gcacctgggc cacgtgagcg gcgagccagt gatcggcggc ctcgaggtcg acatctccgg
    10861 atcgtcctaa gacagcgacg actccagccg cgccgtaggg gaatccggca cggtggtccg
    10921 cgctgtcgcg ggcgaggaca gggatgtctc cgggaacgac cggcgagtcg tccgtccact
    10981 gaagcaccga tgcgacaccg cgggcgatct ggccgcgcag ctggtcgtcc gagagggcgg
    11041 cgagtcgacc gacgtcttcg tcgatcgacc tctgaccgga ggcggggagt acgtcgaggg
    11101 tggaggtcct gatcgaccgc agcacggcgg gcggaaccgc gagatcgtct gcggctgctc
    11161 ggaggagctg ctcgatcttc gcgacgttgc cctggtcggc gatcgtcgct tgggggaaga
    11221 ggagatcgag ttcgaggatg ccgagcgacc actcgtccgc ttccgtcccc ttcaggcctt
    11281 ccaggggctc gtagccgggc gctccctggc gacaacgcca ctccggatcc attcgatgcg
    11341 cgaactcgaa gtcgaggaag cacgggtgcg tgccgttccg catgatgacg ttcttcgggt
    11401 ggatgtcgcc gagcagccat cctgcgcggt gcacggaggc gagagcggcg tcgaggcgag
    11461 cgacggtcgt ggtcagccag gaggtgtacg cagggtcacc gacgcgccac ggtgctggtc
    11521 ggagcagcgg agtcctcgtc atccattcgc gcttcagatc gttcccctcg atgtactcca
    11581 tgaccaggta tcggtgctcc caggccgtga aggatccgta gaagacgggt acgcagtcca
    11641 gggactgcag atcgacgagc acctcctcct catgagccag gcgagtcacg gcgtcgactc
    11701 cgtcggcgtc caacccggcg tgcgggcgcg cctccttgag gaccacgatc gtcccgatcg
    11761 gcacgaattc gtcggtcgtc gcttcagcga gatagacacc accaccgttc gagaagtgca
    11821 gcgctgagag catcgtgaag ccgaaggcga cctcttcctc gttctccgcc ccgacagtga
    11881 cggactccgg tagtgaagcc cacgggggag gtgtgaacgt cggccgccgg acgtcctcca
    11941 cctcgttccc gtccgggtcg agcaccgtcg agacgaagcc gctctccgtc tcggacggga
    12001 cgaaggcgcc gtaacggaag tgcacaggcc cggacttcca ccgccggtcg gacagtacgt
    12061 acgggcctct gaacccgcga agacggacgt cgaggtcctc cagcgctcgg gcgaactcgt
    12121 cgtccgaacc gggatacacg gtgatgaact tcccagctcc cgctcgatcg gcgtacttgc
    12181 cgttctgcat cagaaggtga gaggtggtcg agagatgctt gaaaggcagt cgggaggcga
    12241 agcagtagcg tgcagcagcg gcgaggacct tctccgcgtc atcgagtgtc gacgagaggt
    12301 ggagcttcca tccctgacga gggaggaggc aaccgtccgg catccagttc cgccacggcc
    12361 gcgactccct cacctgccag tcctccggag cgaaggacgc gacgtcgaag gcgtcgccat
    12421 cgatgtcgtc cccctcctcg gcgaccgcgt agaacgggtt gcccgggcgg cagtaccgga
    12481 gatattcgag gtcgagcggc atcgcttccc tttcctgtcc gacttgtctc gcggcgcggg
    12541 atgcggctcc cggcgctgac ttcgaggcta ggaaggtccg cagtcgacca cctcccgccg
    12601 aagtcacgga tgaggatgac cggagtcacg gtgagggcgt gactgcggtc acgggtcggc
    12661 atcccggagt cggagctaca gttgtcgaca tgggctcaac tccggagacg gcggcggaga
    12721 tctccgcgcc gtcagcggca ggacacgagc gggtcgcggt cgcgccgtcc ctgtcgagca
    12781 ccgtggacag gaccgtcatc gcacttcagg cgatcgccct gtgctgcctc gtcctggcag
    12841 ggatcctggg cgtcgtggac tccgcgcaga gaggcacggg tgcagcggtc gcggtcacat
    12901 ggctcgcgct ggtgcctgtg atcgccgggc tctgggccgt ccggccccga ctgatccgag
    12961 cgggacacgg ggtcgccgtg acgacggtgt ccatcgtcgc ggcgacgccg gtcgtcgtct
    13021 tcggccggct cgatttcacg atcccggtcc tcctcctcgt cgtggcgttc gcggtggtcg
    13081 acgtctcgct ccgcgcaggg gcgcacgcga tgatctggat cgcctccgtc ggactggccc
    13141 tccatgtcgg gggcgccgtc ggctcgggga gggcgctgct ctccggagtg ctcgacggtc
    13201 tgctcaacgt ggtgcccgtg gccgtgctga tgtgcttcgg gatcgccctg ggactctctc
    13261 ttcgcggctt cgagagcgag cgatccgccg accagcgtgt gatcaggcgg ttgcatcgcg
    13321 cctccgagac ggagaaggag ctgctgctgt cggacgagcg cgcccggagc gcacgcgagc
    13381 tccacgacgg cctcgggtac aagctgaccc tcgtctcgat gagtctcgag ctcgctgatc
    13441 gcctgcgctc cgccgatgcc gagcaggcgt gggccgaggt ccgcacggcc cgatccacgt
    13501 cgagcgaggc tctcgcggac atgcggatgt gggtacgagc gctcagtccc ttccgggacg
    13561 cgggcgcccg cggcctggct gcgctggagt tgatcgcgga gtccttccgc ggcacgggcg
    13621 tgaccgtgga tgtggtcggc gacgaggcgt cggaccgtgt gctcaccagc gacgatgaga
    13681 ccgcgctcgt cgtctaccga ggcgtgcagg aagggctgac gaacgctctg cggcacggcg
    13741 ctgcccgcag agtccgcatc gatatcgaga cggacgacgt ccggctcgag ctctcgctgc
    13801 tcagcgacat cggcgcggga aggagcaacg ggatcagcga cggcgagcct gtgctggggt
    13861 tcgggctgcg cggcctcgac gatcgcgcga cggctcgcgg aggtcggttg acggcgcggc
    13921 gcatcggcga ccggttcctc ctgcgcctct cgatccctct cggaggcgcc gacggggaac
    13981 gggagagccg cgcctcgtga cggagacgac accgaggcga gtgctgctgg tggaggacca
    14041 gcagatgatc cgccgtgggc tggtcatgct cctctcgacg gtcgagggtg tcgtggtctc
    14101 ggcccaggcc gagaacggac aggctgctct gcacattctg cgcacgacgg aggtggacgt
    14161 cgtcgtcacc gacgcgcgga tgccggtcat gggcggcgtg gagctcgccg ccgagtgtgc
    14221 gcagctccat ccgcgtctgc ccgtcctcct tctgacgacc ttcgacgacg acgcgctcgt
    14281 gcaggcggcc ctctcggccg gcgcttccgg attcctcctg aaggacacct cggtggaggg
    14341 tctcgtcgtg gccctcgacg cggtgatcgc cggcgggatg gtgatcgatc cgcgcgtcgc
    14401 ccggccggcc gtccagccgg gtcgcaccgg cgagagcccg ctgacgctgc tcacgcggag
    14461 cgagcgggtg gtcgccgagc tggtggccga agggcggaac aacagggaga tcgcggccgc
    14521 cctcgtgctc gccgagggca ccgtgaagaa ccacgtctcg gcgctgctgc gcaagctcgg
    14581 cctccgcgac cgcaccgccc tcgcgctcac gctctacaaa ggcttccgcc ccgacggcgc
    14641 ctgaaggcgc tggtcggatt gcggcccagg cgcggccgtc ctcgggcgcc cgacccgccg
    14701 cctatccttg agggcgatgt cgaactcccg cgccgaggcc gcctacctgc gctccctcgg
    14761 cgccttccgg acgccgaccc tggatctcct ccacggccgg tacgccccgt tcgtcgtcgc
    14821 cgccctgtcg ctcgtgttca ccgtcgaccg gcaggtggtg gccgtcgctg acgcgcacgc
    14881 cgaggtgggg gagctgctcg aggagctgcg ctcggccggg tacgacgagg tcgagcgcgc
    14941 gctgccgagc ggcacggcgc gcgaggtgtg ccgctactgg gtccgcgtcg gctggctcgt
    15001 gccgcagatc gagggcgagg ccgaggtcta ccggctgagc gcccacgccg tgagcgccct
    15061 cgagatcacc gggcgcaccg gaggtggacg cacgcgcgtc tcgaactcgc gggtgcgcac
    15121 cctgctggag gcggtcgagc ggctggccgc ggacgtcgat cccgacccgg aggcccgcct
    15181 ctcgcggctc cgcgaggagc gggcgcgcct ggacgccgag atcgccgcac tcgaggaggg
    15241 cgccggtctc gagccggccg acgacgagca gctcctggag gaggccgaga acgtggtgca
    15301 cctcgcccgc gagctgccgg ccgacttcgc gcgggtggcg gagtcgatca aggcgatgca
    15361 gcgcgacgtg gtcgcggacc tgcgccgcga cgtccgcccg accggcgagg tgctgcggga
    15421 gtacctcgag cgaggtcagc acgtgatgca ggccaccagc gagggccgtg cgttcgccgg
    15481 agccctccgc ctcctgggcg accccgagcg gatcgacgcg ctcgccgatc agctgcacac
    15541 cgtgctcgtg cagccgttct cccgcctgat ggaccccgcc cagcgcgcgg agctggccgc
    15601 gatcggccgc cgggtggagc tgggcgtgca ggaggtcctg accgcgcagc gccgcgcgtc
    15661 ccacgtcatc acgggccagg tccgcaccca cgacccggct cgcgaccgcc aggtggacga
    15721 gctgctgcgc gacgtgatgg cggggctcca ggagtggacg ggcgggatct cgccggacgc
    15781 gccggtcgcg ccgctgcggc acctgcccgt cgccgggatc ggccacctgc gccagaccct
    15841 gggagacgtg cgtccggccg gcgggccggc gcccctggcc ggagacgacg gcgacgccga
    15901 gttcgtcggc gacgacagcc gggcctgggg cggtccccgc tacgcggagc tggaggccta
    15961 cgtggcggag ctcggcgacg agttcgatct ggcggacgcg ttcagcgcgg ctccggagga
    16021 cacgcgacgg cccgtcgacc tgctcgggct gctcgagatc gcgcaccgga cgggcctcgt
    16081 cgaccgcgag ggctactccg tcgtgagcac gcgccgaccc gacgggaccg tgcgccgctt
    16141 cgccttcgga tccgtgaccg cccgcaccga ggaggagacc gacgatgagt gacaccctgg
    16201 cgaccgacgg gaccgccgcc gatccgttca tcgcgcccgt gtcgatggag gaggaccccg
    16261 acgagctctt ccccggcgac cgcggcgtcc tcgacaccga ggtgcgccgg gtgctcgtgc
    16321 acgtgctgca gcgccgcttc ctcctcgccg accgccaccg cgagcagtgg gccgtgctcc
    16381 aggagcaccg gcagctgatc gagtcgcggc tgaacgacct gttcgtgcgg ctcgtcgtcg
    16441 accacgagcg cggggtcgcc tacaagcagc aggtgcgctc cgacgaggtg gagatgccgg
    16501 tgctgctgcg cgacctcccc tacacccgcg ccgagacgct ggtgctggtg cacctgcgca
    16561 cggtccatca gcgggagtcg gcggccggcg aggcgtcggc gcgcgtggac gtcgaggagg
    16621 tcgagcagac ggtgctcagc tacttcgcgg acgccgagcg cgacacagcc cgccggcagc
    16681 gcatggtccg caaggcgctg gagcggctcg ggcgcgacgg catcgtcgac gaggagtccg
    16741 cagggcggta ccggatcagc tcgatcgtgg agatcgtgct gagcgcgccg aagctgcggg
    16801 agctgagcga ctggctgcgc gggcgggcgg gcgaagacgc ttcctcggtg gtcgcagaag
    16861 cggcgcccgc cgaggagccc ggctcggacg atccggagga ggcggacgac gacgcgctcg
    16921 aggacgacgg cctcgacgag gacgcggacc cgcccacgga cggcgtcctg cccggagtcg
    16981 atgtcgcgga cgacgagccg ctggacgacg agccgctgga cgacgagccg accgacgacg
    17041 acacccccga cccggaggac gacccccgat gacgatgctc gacaccctct tcggcctgat
    17101 ccccgccgcc tcccgcggtc agcagtggct cgccgaggac ctgcagctgg tcaactgggg
    17161 cggctacgac ggcgcgcacc gggtccgctt ctcgccgggg gccacactgc tctgcggcgg
    17221 ctccggctcc ggcaagtcca cgctgatgga cgcctacatc gccctgatga tgccgcacac
    17281 cacgccgttc aacggcgcct cgaacggcgg agtgacgggc cgtccgcgcg gcgaggacca
    17341 gcgcaacatc ctctcctacg cgcgcggcaa gctcgacgag tcgcgcacgg acgagggcac
    17401 gaccatgcgc gtcctgcgcg gcgacggagt cgacacctgg accgccgtcg cgatgacctg
    17461 ggtcgaccac gacggctcgc gcttcagcgc ggtccgcgcc tggtacgtcc cggccggctc
    17521 ccgggtgctc gaggagaccg tgcggatccg cgcgagcgcc gagggcccgg tcgacctcgc
    17581 cgcgctcgac cgggcggcgg cgcaccgctt ctccgacgcg tcgctgcgcg cggcgggcct
    17641 ggatccgctc ggcaccgacc gcgagttctc ggcgcgtctg cacgcggtgc tcggcatcgg
    17701 agcggcggga gccggatcga aggcgatgag cctgctcgcc cgcatccagg ccggtcagca
    17761 gatcacgacc gtcgacgacc tctacaagcg gctcgtgctc gaggagcccg agaccctggc
    17821 ctccgccgac gcggtcgtcg cccacttcga cgagctcgag agcacgcggc agcggatgct
    17881 caccgcgcgc cagcaggtcg cggcactcga gccgttgcgg ggtttgcgcc tgcgcatcgc
    17941 cgcgtccgcg gagcgcgtgc gcctcatcga cgcgctcggg gagttcgatg ccccggtgtc
    18001 gccggcggcc ctgtggcgcg ctgagcagcg cctcggcctg ctgcgcgacg tcgaggtcga
    18061 gctgcgcgag cgcacccgcg ccgtcgacgc cgtgctccgc gagaagcggg cgctcgccga
    18121 ggcggcggag tcggagcggg acgggctcgc tgaggtgctg cgggcctccg gtggcgaccg
    18181 cctcgagacg gcccagcgcg agctccgcga ggtggagcgg cggctgggag cggcgcgcga
    18241 gaaccgcgcc cggctcgagg aggacctgcg cgctctcggc gagccggaga ccacccgcga
    18301 gcggttcgag gcggtgctcg cccgggcggc gagcgcggcc gacgccaagc gcagcacccg
    18361 tgcggcctgg tcggacgcgg tcgccgagcg gaaggccgcg gcgcgcgatc tcgccgagct
    18421 cgaggcggag cagcgctcgg cctcggaccg tcgggacagc atcccccggc ctctgcacga
    18481 ggcgcgcgag cgggtcgcgg aggcagccag cctcaccgcc gacgacctgc ccttcgtcgg
    18541 cgagctggtc gaggtgcgtg ccgagttcga gccctggcgc gaggcgttca cgctcgccct
    18601 cggcggcttc gcgacgacgc tgatgatcga ctccgcccac ctcgaccgct tccgccgcgc
    18661 catcgactcc ctccggctcc cggtccggct ccgctacgag ggcgtggaga ccgggctcga
    18721 ggaggtgcgg ggcctcgacc cgcagacgct gcccgggcgc ctcgactacc gcgccaccgc
    18781 cttcaccggc tggctgcagg accggctcga ggaccgcttc ggctacgtgt gcgtcgacag
    18841 cgctgcggag ctcgggcgcc accggctcgc cctgaccctc accggtcagc tctcgcaggg
    18901 gcagcgcggt gcgcacggcg gccacggcgc cgcgaacgtc ctcggcttct ccaacaccgg
    18961 tcgtctccgc gagctgaacg ccctggtcga ggcggcccgg gcccgcagcg cggcggccgt
    19021 ctcggcggcg tcggcggcgg aggaggccct cgatgcgctc gacgaccgga tgacgcgcca
    19081 cgcccgcctc gcgctggtga gctgggagac ggtcgacgtc gagtcgctgc tcgccgagca
    19141 ggagcgctgg gaggcggtcg gcgccgaggc ggcggaggcg aaccccgagc tcgccgggct
    19201 gcaggagcag atcgacgggc tgcgcggccg cctcgagcgc ctccgccagg aaatcgcgcg
    19261 cgccggtgtg gagcgcgagc ggatcgaggc ggagtgggcc gtcgtggtcg acgacgtcga
    19321 cgcgagccag gcggttctcg atgcggcgga gcaggcagga cgcgagctcg acgacgacca
    19381 gcgcgccttc ctcgacgccc ggttcacgct gaccgaggcc gcggcgtccg gcagcgcctc
    19441 ggacgtcctg gtccgcttcg acgcagcgct cgccacggca gcgcagcgac tggcggagga
    19501 ccgccgctcc gcggccgagg cgcacgagca gcagcgcgag agcgccggcc ggatcatggc
    19561 cggcttcctc gaccgctggc cgaaccccaa cctgctcgcg gaccccgagg cgtccgcggg
    19621 cgacttcgag cggctgctcg acgccctcga gaccagcggc ctgcaccggc tcgagaccga
    19681 gtggcgcgac agcctgctca cgctctccgg caacgacctc acgagcttcg actccacgct
    19741 cggccgctcg ctgcgggaga tccgcgagcg gatcgagccg atcaacgtga tcatgcagga
    19801 tctgccgttc tacgacgacg gccaccgcct gcagatcacg acgcgcgaga accagtcgga
    19861 ggtgcgccgt cgcttccgcc gcgagctccg cgaggtgcgc gcgcagatcc aggccgtgtc
    19921 cgcggaggag gagcgcgagc aggtctaccg gcggatgtcc cggctcatcc agcggctgcg
    19981 gcgcaccgcg cccgacttcg gcgacctcgt cgacgtccgc aaccacgtcc gggtcagcgc
    20041 cgagcgcgtg gacgccgtca cccgagcgca cgtggcgctg tacgaccaca tcggtgagaa
    20101 gtccggcggg gagtcgcagg agctgatcgc cttcatcgtc ggggcagcgc tgcgctacca
    20161 gctcggcgac gcgggagccg accgcccccg gtacgccccg gtcttcatgg acgaggcgct
    20221 gatcaaggcc gacgcccact tcaccaagcg ggcgatcggt gcgtggcgcg gtctcggctt
    20281 ccagctcgtg atcggcgccc cgaacgacaa gtacagcgcg atcgagccgc acgtcgaggt
    20341 ggagtacgac atcctcaagg acacgcgcgg acgctcctgg gccaggccga aggtgggcct
    20401 ggccccctag ggctgcgtgc cgatcttcgc gtggctgcgc gagtaggcga agtagatcgc
    20461 gaagcccacg gccagccaga tcaggaagcg cagccaggtc tcgatcgaga ggttgagcat
    20521 caggtaggtg cagatcaggg ccgagagcag tgggagccac gggttcagcg ggacccggaa
    20581 accgcgcttc aggtcgggcc gcttgcggcg cagcaccacg acgccgaccg agaccagcac
    20641 gaacgccgag agcgtgccga tgttgaccat ctcctcgagc acgccgatcg gagtgagccc
    20701 ggcgagcagc gcgacgacga tggtcacgac cacggaggtg aaccacggcg tgcgcaggcg
    20761 cgggtggacg gtggccaggc gccgggggag gagtccgtcg cgcgccatcg cgaagatgat
    20821 gcgtgtcgct ccgatcagca gcgtcagcac gacggtggtc agaccggcga cggcgccggc
    20881 cgagatgacc gtcgccatcc aggtctgccc gtggtaggcg aacgcgttgg cgagcgcggc
    20941 cgacgggtcg agctcgcggt aggggaccat gccggtcacg acgagggcga cggcgcagta
    21001 caggaccgtg cagatgatca gcgaggcgat gatgccgatg ggcaggtcgc gctgggggcg
    21061 gcgggtctcc tccgcggtcg tcgcgacgac gtcgaacccg atgtaggcga agaacaccag
    21121 ggaggcgccg gcgatgatgc cgccgacccc gaacgtggcc ggctcgatgc ccgagaggaa
    21181 ctggagcagc ggctgggtca gaccggacgc ggactgcgag ggctcggcgg cggggacgaa
    21241 cggcgtgtaa ttggcggtgt tgacgaactg caggcccgcg atgatgacga acaggacgat
    21301 gaacagcttg atcgcgacga gcaccaggtt gacgcgcagc gattccttga tcccgaaggt
    21361 catcagcgcg ccgagcacga ggacgagcag gatcgccggc acgtcgacca cgccgccgta
    21421 ggtgagcgcc ggcgggaggg tcactcccag ctgctgcagc agcgacccga ggtacgcgct
    21481 ccacccctgc gcgaccacgc tcgctccgag gaacagctcg aggatcaggt cccagccgat
    21541 gatccaggcg aagagctctc cgagggaggc gtaggagaag gtgtaggcgg agcccgacac
    21601 cgggaccgtg gaggcgaact cggcgtagca catggccgcg agggcgcagg cgaaggcggc
    21661 gacgacgaag ctcaggacga tcgccggtcc ggcgatgtca tgggcggcgc ggccggtgag
    21721 ggtgaagatg ccggcgccga tgacgactcc gacgccgaag accgtgagat cgagcgcggt
    21781 cagcgacttc ttgagcttgt actcgggctc atcggtgtcg gcgatcgact gctcgacgga
    21841 cttggtgcgg aggaggctca cggtggttct ctctgtgggc tgcggggtgg aggcgcgagg
    21901 gccactgggg aggatagcgg ggcgggcgcc tctgccgcgc cgggcgtcgc gcgagtacgc
    21961 ttcccggcca tgagcaggat cttctccgtg gcgttcgccg acgtgcaccc cctctacgtg
    22021 gcgaaggcgg agcgcaaggg ccggacgagg gaggaggtcg acgaggcggt ccgctggctc
    22081 accggcttct cggacgagga gctggcccgg cacctcgaga gcaggacgac cttcgaggag
    22141 ttcttcgcgg cggcgcgcct gcctccggag gcctcggcga tcacgggggt gatctgcggc
    22201 gtgcgggtcg agacgatcga ggatccgctg atgcagcgca tccggtacct cgacaagctg
    22261 atcgacgaga tcgcgaaggg acggccgatg gcgaaggtgc tgcgggctcc cgcggccggc
    22321 tgagccgccg gacccgggcg ctcctccaca ggcgccgatc cgctccggtt ctccccggtc
    22381 cgggccggcg ggatcctgcg ccgccggcga cgcgagcagg gtgtcgggca tgacatccac
    22441 acagcgaacc cctgctcctc cgtcccgccg ccgcgatccc gaagtcctgc gggcgagcgc
    22501 ga
//
