LOCUS       NZ_POVS01000032        23222 bp    DNA     linear   CON 15-SEP-2024
DEFINITION  Paenibacillus sp. F4 F4_contig_31, whole genome shotgun sequence.
ACCESSION   NZ_POVS01000032
VERSION     NZ_POVS01000032.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. F4
  ORGANISM  Paenibacillus sp. F4
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 91065)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Genome sequencing and comparative analysis of polymyxin-producing
            Paenibacillus strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 91065)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2018) Infectious Disease Research Center, Korea
            Research Institute of Bioscience and Biotechnology (KRIBB), 125
            Gwahak-ro, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-JAN-2018
            Assembly Method                   :: CLC Genomics Workbench v. 11.0
            Assembly Name                     :: F4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 524.4x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002894905.1-RS_2024_09_15
            Annotation Date                   :: 09/15/2024 04:37:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,419
            CDSs (total)                      :: 5,299
            Genes (coding)                    :: 5,203
            CDSs (with protein)               :: 5,203
            Genes (RNA)                       :: 120
            rRNAs                             :: 10, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 102
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 42 of 96
            Pseudo Genes (incomplete)         :: 67 of 96
            Pseudo Genes (internal stop)      :: 14 of 96
            Pseudo Genes (multiple problems)  :: 22 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:44:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 63487
            Orig. end                         :: 86709
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            POVS01000032.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23222
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23222
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23222
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:13222](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13222
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(83..99)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.94"
                     /tool="antismash"
     misc_feature    963..974
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 20.11"
                     /tool="antismash"
     misc_feature    1006..1022
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.05"
                     /tool="antismash"
     gene            complement(1031..2158)
                     /locus_tag="C1T21_RS26365"
                     /old_locus_tag="C1T21_26370"
     CDS             complement(1031..2158)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010344663.1"
                     /locus_tag="C1T21_RS26365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26370"
                     /product="transglutaminase domain-containing protein"
                     /protein_id="WP_103050327.1"
                     /transl_table=11
                     /translation="MNRKIGVRLVKCLVAGAALAVLLPQAVEWGSNVYAASTKPAASVS
                     SQQLQNKLLQAMATRSETLTFTYQGRVNGLKQQLQTAIQQAMESDPYVNYTIKSYAFSY
                     TGTTTSAQVTIRLSYRETKEQTAYVDSTVKAVLGDIITKGMTDHEKVKAIHDWIVVRLK
                     YDETQQKYTAYDGLKTGSTVCQGYSLLAYKMLERAGITNRIVEGRAGGQLHAWNLVLLD
                     GRWYHMDTTWDDPTPDRANEVSTSYYLLTDTEMRRDHSWVKPYPQANTSYRETLSALVA
                     AGGSKAAVYQKLYDTLEYPLQDGKGLVKSSADIKEQVRKIVNKGGTTLTFAYQGTERSL
                     KEDLQSLYQLGLKSISYQITDLGSTGNLRVTLKWT"
     CDS             complement(2179..2352)
                     /gene="allorf_65666_65839"
                     /locus_tag="allorf_65666_65839"
                     /protein_id="allorf_65666_65839"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIKLSTNDKTARCPICYLAEYDVTTCLELRPYSSATDKTRAFGAT
                     VFMVRYSCLQLC"
     CDS_motif       complement(2224..2352)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MIKLSTNDKTARCPICYLAEYDVTTCLELRPYSSATDKTRAFG"
                     /locus_tag="allorf_65666_65839_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(2179..2223)
                     /prepeptide="core"
                     /locus_tag="allorf_65666_65839_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="1598.0"
                     /monoisotopic_mass="1596.8"
                     /core_sequence="ATVFMVRYSCLQLC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIKLSTNDKTARCPICYLAEYDVTTCLELRPYSSATDKTRA
                     FG"
                     /leader_location="[2223:2352](-)"
     misc_feature    2397..2412
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.16"
                     /tool="antismash"
     misc_feature    complement(2400..2415)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: strong, score: 26.82"
                     /tool="antismash"
     gene            2439..2684
                     /locus_tag="C1T21_RS26370"
                     /old_locus_tag="C1T21_26375"
     CDS             2439..2684
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007432154.1"
                     /locus_tag="C1T21_RS26370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26375"
                     /product="FeoA family protein"
                     /protein_id="WP_016820309.1"
                     /transl_table=11
                     /translation="MPECISLLRTPLGQTVRLQSLAPLHPSLRRRLTDMGINEGSIIRL
                     KKISLLGGPIVIECNGQLVGLRQNQVKQLEVVPTWT"
     gene            2675..4684
                     /gene="feoB"
                     /locus_tag="C1T21_RS26375"
                     /old_locus_tag="C1T21_26380"
     CDS             2675..4684
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="feoB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311964.1"
                     /locus_tag="C1T21_RS26375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26380"
                     /product="ferrous iron transport protein B"
                     /protein_id="WP_103050328.1"
                     /transl_table=11
                     /translation="MDMIALFGNPNTGKTSLFNKLTRTYAEVGNWSGVTVEKKTGILRD
                     KSAVLVDLPGAYSLLPLSLDEGVATRYLLEEPPTALINIVDASQLQRNLYLTVQLLEYG
                     RPLVLGLNMTDVADATGLRVNKELLADQLNVPIIPMVARTGSGSKQMLASLREVRRTSN
                     AFQLDYGPAVEAAITDICNLLPNASVPQLRWAALQCLEGNPVVMEWMTNEVQREQVTAR
                     IHRCEEELLAEGHAITPAQHIRSVRTAWIADLCTKALDTSKLRPHSLTDRLDALLTHRY
                     LGIPIFLLLMYATFKFTFDWAGTILSDMLDGFFSGTLSTWISELLVHLNASAFTQSLVV
                     DGIVAGVGGVLVFLPQIAILFLIISVIEDSGYMARVTILMDRLMQAVGLNGKSFIPFII
                     GFGCNVPAIMAARTIEQPRERLITTLLVPFMSCSARLPVYALFAGVFFPTHAASIIMLM
                     YVLGIVVSLILAKIFSKVSILSGEPSLFIVELPPYRVPQALTLFRSTWEKVKGFVRKAG
                     TIILAGSVGIWLLSNFGPQGFGAEMNDSLLATVGGWFAPLLAPLGFGTWQAGASLLTGF
                     MAKEVVVSTMNIIYHVPDMQGLELQVRQAFTPLASFSFMVFILLYVPCLATVAVIRKET
                     LSWRWTAFSVIYPLTVAYIIAVLIYQCGRLLGWG"
     gene            4721..4903
                     /locus_tag="C1T21_RS26380"
                     /old_locus_tag="C1T21_26385"
     CDS             4721..4903
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373081.1"
                     /locus_tag="C1T21_RS26380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26385"
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="WP_103050329.1"
                     /transl_table=11
                     /translation="MINIIILLAILGYSAWVLVRFLRKSRQGACAGCSSSKSCPGCAGS
                     SMNEDTRKTTAAHKG"
     CDS_motif       4721..4759
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MINIIILLAILGY"
                     /locus_tag="C1T21_RS26380_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4760..4903
                     /prepeptide="core"
                     /locus_tag="C1T21_RS26380_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.90"
                     /molecular_weight="4691.3"
                     /monoisotopic_mass="4688.3"
                     /core_sequence="SAWVLVRFLRKSRQGACAGCSSSKSCPGCAGSSMNEDTRKTTA
                     AHKG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MINIIILLAILGY"
                     /leader_location="[4720:4759](+)"
                     /alternative_weights="4709.3"
                     /alternative_weights="4727.3"
                     /alternative_weights="4745.4"
                     /alternative_weights="4763.4"
                     /alternative_weights="4781.4"
                     /alternative_weights="4799.4"
                     /alternative_weights="4817.4"
     gene            complement(5046..5762)
                     /locus_tag="C1T21_RS26385"
                     /old_locus_tag="C1T21_26390"
     CDS             complement(5046..5762)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373082.1"
                     /locus_tag="C1T21_RS26385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26390"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_103050330.1"
                     /transl_table=11
                     /translation="MTQENKSPFLQLDQVSFGYGSKEILHEINWNVSDHQITVLLGPNG
                     AGKSTLLSLIAGLHQVQKGTIQFNQTIIDFENQNYKSMVGYLQEFPFYYPALSVLEMMR
                     LIGGLRQVPKNQLEIRIAKWLERFKLEDYQNIKMEELSQGTKKRVALASTLLHEPTILI
                     LDEPTNGLDPDQVMIVRSTLQEYLTEGRVILLSTHIIGLAEKLADQVAILRNGRITYTG
                     RSTIDLETLYITHQHD"
     gene            complement(5776..7029)
                     /locus_tag="C1T21_RS26390"
                     /old_locus_tag="C1T21_26395"
     CDS             complement(5776..7029)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373083.1"
                     /locus_tag="C1T21_RS26390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26395"
                     /product="hypothetical protein"
                     /protein_id="WP_103050331.1"
                     /transl_table=11
                     /translation="MTSIKLCEILYLNQLRKLTKMDAALFILLLILIPNGLANVTLRLN
                     SLGFKAMMWAIIYGISGFLIHIGISISTSKIEEIRFLWSIGKGNLFLTQYTMIKKVPFL
                     ILLLWMVVGQILWGVHNNHIYNMVSGLIIGVLFAEIFGYIMLFRKFYGYAISFFFLSLN
                     VIYFILPMSLSVRILTWLLLCISMGYIALYFAQRSWSVFLQYHGPKKNLNRRGWLSQSP
                     LLKKELLFIIRRGNLFSFFILALGIEVLNYYIIRESPLILPISSAVLSWFAVDIWAVKS
                     LIIEEKGLLIYKATLFAWKKMLRTKWLILCVVTIGIISMHQWVWGIYLHISPMSLLIQI
                     IWNVFLSITLISFGMPLGYKFISIDYLGNYRIKFFGNWVIAMSMLLLLYLHQFHKVLFA
                     VISIMIYIRFIFFYRKVS"
     gene            complement(7046..9208)
                     /locus_tag="C1T21_RS26395"
                     /old_locus_tag="C1T21_26400"
     CDS             complement(7046..9208)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="C1T21_RS26395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26400"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_308411676.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3e-39, bitscore:
                     126.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLKFNKKVPFIEQMEHSECGLACLAMILGFFGHNISLTELRNQV
                     GAVRAGMSMQQLQEIGSTYHLTSRGYRAKASQLNELTAPLILLWDNQHFVVLEKIKKKK
                     AIILDPAFGRLILSLQEFTEKYSGFALSLIPVKDFRNKRKIPKWTFYIKLAFKSRKLLI
                     SVFLVSILLQGLGISIPKITQFTVDNLLESKNYSFLITLGGAIFTIFVFSQLFQFLRGY
                     LIAKLQSQMDTSMMTQFIDKLFKLPFDFFENRKGGELVFRANSNVTIRRVLSNRVITIF
                     IDGLLLITYAILMINQLWQIGLIVTIVGFLMLLIIVLSSFITHRLSRKEISSQAEMHGF
                     LSEHIHGITDVKVLGFENRVFNKWEELFKKQLATTEKRVIWNVSLDSMTVSIQFVFPLL
                     ILWIGFHYVFEGWITLGGLLGLQTLSTAFMVPIASLGSTLSELVTVGSYIQRIQDVIEN
                     VEEPSGTQKPNHTFRGYIKFKDVSFNYYRFGKYVLKDINLEILPGEKVAIVGASGSGKS
                     TLAKLILGLYKASLGEVSIDNIPLNQWHLSELRQKIGVILQETKLFNVSILDNIGMDNG
                     DCTIDMVVQAAKQADIHRFIMSLPLGYQTVVSENGLNFSGGQRQRILLARAFLAEPQIL
                     LLDEATSSLDSVSEQLITGFLQERHCTQIIIAHRLSTIQRADRIIVLDQGEIIEQGNHQ
                     ELIDLKGQYFNLYNSQKTDFQFESVL"
     gene            complement(9192..9434)
                     /locus_tag="C1T21_RS26400"
                     /old_locus_tag="C1T21_26405"
     CDS             complement(9192..9434)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373085.1"
                     /locus_tag="C1T21_RS26400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26405"
                     /product="response regulator transcription factor"
                     /protein_id="WP_103050333.1"
                     /transl_table=11
                     /translation="MRENQNLSPKEQKVAICIAQGYKDSEISQDLSISMRRTAEIVASI
                     KEKWNIKTRVEIGIFAYHYGLVFLTEGMEVHSSEV"
     misc_feature    9532..9545
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.08"
                     /tool="antismash"
     misc_feature    9546..9555
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            9670..9891
                     /locus_tag="C1T21_RS26405"
                     /old_locus_tag="C1T21_26410"
     CDS             9670..9891
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373086.1"
                     /locus_tag="C1T21_RS26405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26410"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_103050334.1"
                     /transl_table=11
                     /translation="MTKQEMIQAWKNPKLRVAGEGIDHPAGDALVELSADELARVHGGL
                     GVQPDSTPTITVTVIGVTVLVCFPGHAG"
     CDS_motif       9670..9801
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MTKQEMIQAWKNPKLRVAGEGIDHPAGDALVELSADELARVHGG"
                     /locus_tag="C1T21_RS26405_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9802..9891
                     /prepeptide="core"
                     /locus_tag="C1T21_RS26405_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.40"
                     /molecular_weight="2771.2"
                     /monoisotopic_mass="2769.5"
                     /core_sequence="LGVQPDSTPTITVTVIGVTVLVCFPGHAG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTKQEMIQAWKNPKLRVAGEGIDHPAGDALVELSADELARV
                     HGG"
                     /leader_location="[9669:9801](+)"
                     /alternative_weights="2789.2"
                     /alternative_weights="2807.2"
                     /alternative_weights="2825.3"
                     /alternative_weights="2843.3"
                     /alternative_weights="2861.3"
     misc_feature    9947..9960
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.67"
                     /tool="antismash"
     gene            10001..13222
                     /locus_tag="C1T21_RS26410"
                     /old_locus_tag="C1T21_26415"
     CDS             10001..13222
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373087.1"
                     /locus_tag="C1T21_RS26410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26415"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_103050335.1"
                     /sec_met_domain="DUF4135 (E-value: 5.8e-96, bitscore:
                     314.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.8e-64, bitscore:
                     208.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEQIMRALFLHERKNLVDQAFQGFNYKNWRQDKEKTIELIDEWF
                     KFALISTESKKEARFKASSMNEEIFGALIQSTENLKWDENYLAIIKEYQADWFRVLEEA
                     LKMNENHPVLQNESRTMNVLIRPFIIWARNQLKQHLSKIDNAQDFILHENTINSVLHTL
                     SFQLTQIAGRSFVLELNIAKTLEELEGQTPEERFISFIEKKFVGHKQLVSFFSEYAVIA
                     RTLAERTMLFVNVIKETLDRYLLNRSMIIDIFSLHSSELIRIDAGFGDSHQQGRTVMRL
                     YLANGQSFMYKPKPLDISLHFQALIQWFNDKGFSPFLQRNSVIALEGYGYEKFIEAKPC
                     KTEEEIQCFYTRLGALLAIIYLLDGTDFHYENLIAFGEHPMLIDLETLFHNQVYHNVPD
                     SADIEAQFRIRNSPLGTSLLPILFHQDDKGFGIELSGVNGEKQMTPYPVLSLVDVNTDN
                     MRYIRKSQATSTGNNRPSLEGELKNAGDYTTEIVNGFQLLCSMLLQYRMDLLAPTSPLF
                     TFKDAPVRIVLRSTQFYTNFLLESRHPDYGRDALNQENLLDRIWFSWLDDRIISSELQD
                     LRVGDIPYFTSKPSSLDLWDSYGKCIKDVFTRTSMSIVEDRLKSLTTDSISLYSDWISS
                     SIAGSSLGKHVHKVHDPSPNEKVMINGYSPKPLHSEKFLETARILGDELIKKSVFSPSK
                     KYVTWIGMNLNYRGQLYLSALSPGLYDGTAGIALFLAYLGKISEDEKYTSVALAALETA
                     LSKIPVHLKFPSAFYGQASLLYILSHFENLLGFNDAWSKRKSDIINNLDDSVEEDAFFD
                     LLGGSAGVIHVLLNEYNHTKSAKTLEVAIKYGEHLLKHGINNNGVISWISNVSPTPYVG
                     FGHGSIGIASALFRLAAVTKKDCYYATAEKALAHLTEAYSPDYFNWIDHGNKENHDLAN
                     WCHGASGIGIGLTLCIPYLKSSLVPGIVHNIERAVNTTLKYGFNKSHCICHGSLGNIEL
                     LILAGQALNRPEWVTEAKKQGNNALNYYFEHGKFKTGLPTALDSQGLWLGLSGIGYQLM
                     RLYSLNSLPSILSLQEPLQKESSCI"
     gene            complement(13340..14863)
                     /gene="xylB"
                     /locus_tag="C1T21_RS26415"
                     /old_locus_tag="C1T21_26420"
     CDS             complement(13340..14863)
                     /EC_number="2.7.1.17"
                     /GO_function="GO:0004856 - D-xylulokinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005997 - xylulose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="xylB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210: glycerol kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311965.1"
                     /locus_tag="C1T21_RS26415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26420"
                     /product="xylulokinase"
                     /protein_id="WP_103050336.1"
                     /transl_table=11
                     /translation="MQEKLNQEQERYVIGVDLGTSAVKTVLVNRKGQVAYETSQSYPLH
                     QPKAGYSEQHPEDWVSGTLASLKQLVEKAGIGGTDAVDGISFSGQMHGLVLTDKEGQVL
                     RPAILWNDTRTTAQCRCIEEKLGSKLLKIARNRALEGFTLPKLLWVQEHEPDVLARAAH
                     FMLPKDYVRYCLTGELATEYSDAAGTLLLDIANKQWSEEIAAAFDLPLSLFPPLVESFD
                     QTGTLLPEIAEQSGLSPETKVFAGGADNACGAIGAGILSEGRTLCSIGTSGVVLSYEER
                     KDIDVQGRAHFFNHSEQDAYYIMGVTLAAGYSLTWFKDTFAPEHSFDALLEGVDSVEPG
                     SRGLLFTPYIVGERTPHPDATIRGSFIGMDAGHKLAHFTRAVLEGITFSLKESIDILRG
                     TGKTVNEVISIGGGARNEAWLQMQADIFNADIIKLESEQGPALGAAMLAAYGSGWFESL
                     QACAEAFLREAARYSPNPERVAQYEGLYELYREVYLHTRELSEHLAVYR"
     gene            complement(14921..16237)
                     /gene="xylA"
                     /locus_tag="C1T21_RS26420"
                     /old_locus_tag="C1T21_26425"
     CDS             complement(14921..16237)
                     /EC_number="5.3.1.5"
                     /GO_function="GO:0009045 - xylose isomerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="xylA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007432158.1"
                     /locus_tag="C1T21_RS26420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26425"
                     /product="xylose isomerase"
                     /protein_id="WP_103050337.1"
                     /transl_table=11
                     /translation="MAYFEQVSKINFEGKQSTNPFAFKFYNPQEIVAGKTMEEHLRFSM
                     AYWHTLVAGGSDPFGVETAERPWSKFTGLDLAKARVEAAFELLDKLNLPYFAFHDVDIA
                     PEGASLKEFYSNLDTIVDLIEEHMKATGKKLLWNTANMFSHPRYLHGAASTCNADVYAH
                     AAAQIKKGLEVGKRLGADNYVFWGGREGYETLLNTDLKLEQDNLGRMFHMAVDYAREIG
                     FDAQFLIEPKPKEPTKHQYDFDAATTIAFLQKYDLDQHFKLNLEANHATLAGHTFDHEV
                     RVARINGMLGSLDANQGDLLLGWDTDEFPVDLYDATLTMYEVLQNEGLGRGGINFDAKV
                     RRASFEPEDLFLAHIAGMDTYAKGLKVAAKLIEDRVFEDFIEKRYSSFKEGIGADIVSG
                     KATLASLAEYALANETPRKNVSGRQEYLKAKLNQYILAD"
     misc_feature    16323..16339
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.88"
                     /tool="antismash"
     gene            16373..17545
                     /locus_tag="C1T21_RS26425"
                     /old_locus_tag="C1T21_26430"
     CDS             16373..17545
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017425974.1"
                     /locus_tag="C1T21_RS26425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26430"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_103050338.1"
                     /transl_table=11
                     /translation="MNVTGDQALVKKLNKSIVLERIRLHAPLSRAQLSSQTGLNKATVS
                     NLVAELITDGLVYETGLGESSGGRKPLMLLFNSRAGFVLGIEVSVQYIKGALTDLAGTI
                     ETELALSLTQHDPAFVMEQIRKLVQELMQATPPSPHGIVGIGLGVPGMVDETGTVLFAP
                     NLGWEEVPLRQQLEAELDLPVVVDNEANVGAQGELYYGMDGDHRQQVRDLVYISAGSGI
                     GAGIIIDGKPYQGAWGYAGETGHMTIDWNGRLCSCGSRGCWELYASEKAYVASTLKLPA
                     HNTAELLPFAQQGEASTLSVLDDIGRYLGVGITNIVNSLNPGMLIIGGPLAEARPWLEQ
                     SMRDVIDERALPYHRRQLQIRFSTLGSRSTMLGAAYAATAPFLGRVRVSL"
     gene            complement(17646..17876)
                     /locus_tag="C1T21_RS26430"
                     /old_locus_tag="C1T21_26435"
     CDS             complement(17646..17876)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010344656.1"
                     /locus_tag="C1T21_RS26430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26435"
                     /product="glutaredoxin family protein"
                     /protein_id="WP_007432162.1"
                     /transl_table=11
                     /translation="MEKAIVYTSTNCPHCRQVKSYLSEKGVEYEERNIETNEAFAQEVW
                     DMGIRAVPLTLIGEERISGMNKTKFEKVLNA"
     gene            complement(17935..18876)
                     /gene="trxB"
                     /locus_tag="C1T21_RS26435"
                     /old_locus_tag="C1T21_26440"
     CDS             complement(17935..18876)
                     /EC_number="1.8.1.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trxB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820315.1"
                     /locus_tag="C1T21_RS26435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26440"
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="WP_023990316.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.6e-52, bitscore:
                     168.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKSIIIGTGPAGLTAAIYLARANMSPLVIEGPQPGGQLTTTTEV
                     ENFPGFPEGIMGPDLMDNMRKQAERFGAEFRTGWVNKVDTTARPFTLDVEGLGELVTDT
                     LIISTGATAKYLGIPGEQDNIGRGVSTCATCDGFFFRGKEIVVIGGGDSALEEANFLTR
                     FASKVTLVHRREEMRASKIMQDRARANNKIEWALNRTPVEVIADENGVTGLKVLNNATG
                     EEEIITVSGVFVAIGHHPNTGFLEGQITTDANGYIVVNPGTSETNVPGVFACGDVQDTR
                     YRQAITAAGSGCMAAMDSEKYIESLEHSALAL"
     misc_feature    18978..18995
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.23"
                     /tool="antismash"
     gene            19158..19889
                     /locus_tag="C1T21_RS26440"
                     /old_locus_tag="C1T21_26445"
     CDS             19158..19889
                     /GO_function="GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311970.1"
                     /locus_tag="C1T21_RS26440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26445"
                     /product="ZIP family metal transporter"
                     /protein_id="WP_103050339.1"
                     /transl_table=11
                     /translation="MNDVFVGSFISALSTGLGAVPILFMRNITHRLRDVLLAYAAGIMT
                     SASVYNLIPEAIQHSNWFVLTAGILLGCLVLLVMEMYIPHADLEDPDSKTFQLESKSFL
                     IIAAITLHNLPEGLSVGVSYASETQNLGNLIAFSIGLQNAPEGFIVALFLVNQNIGRFK
                     ALGIATLTGAVEIITSLIGFYLSSWVNGLVPYGLAFAAGAMMFIVYKELIPESHGDGNQ
                     RIATFSFILGLITMIGLTEWL"
     gene            complement(19971..20432)
                     /locus_tag="C1T21_RS26445"
                     /old_locus_tag="C1T21_26450"
     CDS             complement(19971..20432)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820316.1"
                     /locus_tag="C1T21_RS26445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26450"
                     /product="hypothetical protein"
                     /protein_id="WP_103050340.1"
                     /transl_table=11
                     /translation="MTIAFIVVAAVAFIFLLVFNTKMTRKSSPKTRPTEEESRQRSKRP
                     YPVQVEPEARERIDPTREMPHKDIDVEEHHAEEQHKVPDIQTDKKVEKDRENIKDAYGD
                     QDYRAALRGFARKEEEKDGRSQLSNGKKETHKSEDEQYREALRSMNQKK"
     gene            complement(20443..20997)
                     /locus_tag="C1T21_RS26450"
                     /old_locus_tag="C1T21_26455"
     CDS             complement(20443..20997)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688620.1"
                     /locus_tag="C1T21_RS26450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26455"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_103050341.1"
                     /transl_table=11
                     /translation="MTTRIMIVYDSENGHTERLARSIAEGAHLEHTEVLLKHVNEADVN
                     ELVSVDAIIWGCPGHFGTISSALKSWIDKLGYLWAQGKLVDKIGAVFCTTATVHGGLES
                     TLLNLITPMLHQGMIIVGLPANITENALYGSYYGVGVTCPVETDPNGPPNLPTGDDLAL
                     GRSLGKRVAEIAGRYRSAERE"
     gene            21131..21766
                     /locus_tag="C1T21_RS26455"
                     /old_locus_tag="C1T21_26460"
     CDS             21131..21766
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820318.1"
                     /locus_tag="C1T21_RS26455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_26460"
                     /product="HlyD family secretion protein"
                     /protein_id="WP_103050342.1"
                     /transl_table=11
                     /translation="MNSRAILVNLLVIIIILAGGGAAAYYYNQSANYIKTDNAQVSGQA
                     VTVASPGAGKLTGWNAEVGKTYTAGSTLGSVEGGGSRISVTIPTDGTIVQQSAVNNSIV
                     GAGTPLAKAFDLNNLWITANIDETAVQDLQVGQTVDVYIDAYPDTSLSGKLEKIGLATA
                     STFSLLPTSNTTANYTKVTQVVPVNISIQGYKGLGIIPGMSATIRVHK"
     misc_feature    complement(21160..21175)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.77"
                     /tool="antismash"
     misc_feature    complement(21970..21984)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.48"
                     /tool="antismash"
     misc_feature    22754..22769
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.92"
                     /tool="antismash"
ORIGIN
        1 gcaaatgctt gacgcaggcg aggacaacga tgccaccgcc aatcgctcct gcaaaatacg
       61 ctgcattgat gtatccccac catgcctcgc tcttgtgcaa aacctgctga gcgaaagcaa
      121 gcgtgaacgc gcctacccaa accgaacccc ctagaagatc aatcatatcc ataaaaataa
      181 gagctttcag tctgcgactg gctccgatga ggctccagcc ttcacgcagt atctcctttt
      241 tacgtttggg aggtagtgcg gggctctctg attccgggcc atacagtgta tcttccaact
      301 gtgcgggagg caagtcatgg tgcccttgcc cgggctcagt accagtttcg gaaaccgaaa
      361 catctccacc tcgcaccctt gttccaggtt gcagcaaata atgggctttg ccctctagtg
      421 gatctcgaac caggctggtg aagatcattg ctaccatata cagcccgcca gccaccagca
      481 gtgttttttc cgagcctagc atggctacga gcacaccact aagcccccac cccgctaatt
      541 gcaccgtctg atcgctgacc gataccagac tgtttgcccg catgagtcct tccccggacg
      601 caaggcgggg aatcagcgca ttacgcgcag gcgtggtcca tccgtccaga aaggacatgg
      661 ctgccaccaa cgtaaacaca atcacccata tcggctccgt gcccgctgac cacaagtggc
      721 ccagcagaac agcgaagaaa gccagttgtc cgaactggga aacgaataaa ataaaaggaa
      781 gctggaatcg ggccaaaatg agcggtgcta aaaagccgct gatcatctgt gctcccattc
      841 gcagcaacgg aacgagcacc gaagagaaga tggagtccgt ttcatgaaaa accagagaca
      901 caagtgccat aatgtaaaga atgtcggccg cattagacat ggtctgcgtg ccaagcaaat
      961 aggtaaagga acgcttgtgc atataaataa aatactcctt tgttaatgta gcttttttac
     1021 agcaagatga ttaggtccat ttcagggtta cacgaagatt gccggtactt cctagatccg
     1081 taatctgata ggaaatggat ttcaaaccga gttgatataa ggattgtaaa tcctccttga
     1141 ggcttcgctc cgttccctga taggcaaagg taagtgtcgt ccctccctta tttacaatct
     1201 tacgtacctg ttccttaatg tcggcggatg atttaaccag acccttgccg tcttgcagcg
     1261 gatattcgag ggtatcgtac agtttttgat acacagcagc ctttgatcct ccggcagcta
     1321 ctagtgctga taaggtttcc cgatacgatg tattcgcctg aggatacggc ttaacccatg
     1381 agtgatcccg ccgcatttcg gtatccgtta gcagataata tgaagtgctt acctcgttcg
     1441 cgcgatccgg ggttggatca tcccatgtcg tatccatgtg ataccatcga ccatctaata
     1501 aaaccagatt ccatgcatgc agctggcccc ctgctcttcc ttccacaatc cggttcgtaa
     1561 tgcctgcacg ttccagcatt ttataggcca gcagtgaata accctgacag accgtgcttc
     1621 ccgttttcag gccatcatag gctgtgtact tttgctgtgt ttcatcatac ttcaggcgaa
     1681 cgacgatcca atcatgaatg gcctttacct tctcatgatc cgtcattccc ttcgtaataa
     1741 tatcccccag caccgcttta actgtgctat ccacatatgc tgtctgttcc ttcgtctccc
     1801 ggtagcttaa acgaatcgta acctgagcgg aggtcgttgt gcctgtatag ctgaatgcat
     1861 agcttttgat cgtataattc acatacggat cgctctccat ggcctgttgg atggccgtct
     1921 gtaattgctg cttgagaccg ttcactcgcc cttgatatgt aaaggtcagc gtttcactcc
     1981 gcgtagccat tgcctgtaaa agcttgttct gaagctgctg cgatgatacg gatgcagccg
     2041 gcttggtcga cgccgcatac acattgctgc cccactctac agcctgcggc agcaacacag
     2101 ccagcgctgc acccgcaacc agacatttta caagcctaac cccgattttt ctgttcatac
     2161 agagcgttcc tgcccttctt aacatagttg taaacagcta tatcttacca taaaaacagt
     2221 tgctccaaac gctctagttt tgtcggttgc agacgagtaa gggcgcagtt caagacaggt
     2281 tgtgacatca tattcggcta gataacagat gggacaacga gcagttttgt cgttcgtaga
     2341 gagttttatc acagcaatct aggtttcctc atgatatggt actggcatcg gaagtaaatg
     2401 atattgattc tcattctaga tcagaaaggc tgagcaccat gccagaatgt atctcactcc
     2461 ttcgtacacc actgggtcag actgtgcgtt tgcaatctct cgcccctctt catccctcat
     2521 tgcgccgccg tttaacagac atgggcatta acgaaggttc catcatacgg ttaaaaaaaa
     2581 tcagtttatt gggcggtcct attgtcattg aatgcaacgg ccaactggtc ggccttcgcc
     2641 aaaatcaggt gaagcaactg gaggttgttc caacatggac atgatcgctc tattcggtaa
     2701 tcccaacaca ggaaaaacct cattattcaa caagctgact cgtacgtatg cagaagtagg
     2761 aaactggtcc ggcgtcacag tggaaaagaa aacaggaatc ctgcgtgaca agtctgccgt
     2821 attggtggat ttgccgggcg cctactcttt gctccctctt tcgctggatg aaggtgtcgc
     2881 aactcgatat ttgctggaag aacctcctac ggccctgatc aacattgtgg atgcctccca
     2941 gctccagcgt aatctctatc tgaccgtaca actactggag tatggccgtc cgcttgtact
     3001 aggcttaaac atgactgacg tagctgatgc cacgggtctt cgtgtaaaca aggaattgtt
     3061 agctgatcaa ttgaacgttc ccatcattcc tatggtggcg cgtacaggca gtggaagtaa
     3121 gcaaatgctc gcttctcttc gggaggtaag acgtacatcc aatgcttttc aactggacta
     3181 cggccctgcc gttgaagctg ctattaccga tatttgcaat ttgctgccga atgcatctgt
     3241 accgcaactg cggtgggccg cactgcaatg tctggaaggc aatcctgtcg tcatggaatg
     3301 gatgacgaat gaggtacagc gtgaacaagt aactgcacgc atccaccgtt gcgaggaaga
     3361 acttctcgct gaaggccatg ccatcacccc tgctcagcat attcgttctg tacgaacagc
     3421 atggattgct gatctgtgca ccaaggcact cgacacctcc aagctcagac cacacagcct
     3481 gacggatagg ctggatgcac tattaactca ccggtatctg gggattccga tctttttgct
     3541 gctgatgtac gctaccttca agttcacctt cgattgggcg ggtacgatcc tttcagatat
     3601 gctggatgga tttttttcag ggacactcag cacttggatt tctgagttac tcgttcactt
     3661 gaatgcgtcc gcttttacgc aaagtctagt cgtggatggc atcgtggctg gagtcggggg
     3721 tgtgcttgtt tttctgcctc aaattgctat tttatttctg ataatttcag tgatcgaaga
     3781 ctctggttat atggcacggg tcacgatact catggatcgc ctgatgcaag ccgtaggctt
     3841 gaacgggaaa agcttcattc ccttcatcat cggatttggc tgcaatgtcc ctgcgattat
     3901 ggcggcacgc accattgaac agcccagaga acgtctcatt acaacattgt tggtaccctt
     3961 tatgtcgtgt tctgcccgtt tgccggtata tgcgttgttt gcgggtgtgt ttttcccaac
     4021 acatgcggca agcatcatca tgctgatgta tgtgttagga atcgtcgttt cgcttatact
     4081 tgccaaaatt ttttccaaag tatccatttt gtcgggtgag ccctctctct tcattgtgga
     4141 acttcctccc tatcgagtgc cgcaggctct tactctattc cgcagcacat gggagaaggt
     4201 caaaggcttc gtccgtaaag ccggaaccat tattcttgca ggttccgttg gcatctggct
     4261 cttgtccaat ttcggtccgc agggcttcgg ggcagaaatg aatgacagcc tgcttgccac
     4321 cgttgggggt tggttcgctc cattactggc ccctctcggt tttggcacct ggcaagcagg
     4381 ggcttccctg ctcacaggct ttatggccaa ggaagttgtc gtatcaacga tgaatattat
     4441 ttaccacgtt cctgatatgc agggacttga actacaagtc agacaggcct ttacaccgct
     4501 tgcctctttt agctttatgg tgttcattct gttgtatgtt ccgtgtctgg ctacggtagc
     4561 ggtcattcgt aaagaaaccc tttcgtggcg ttggaccgca ttttctgtga tctatccttt
     4621 gaccgtcgca tatatcatcg ccgttttgat ctatcaatgt ggcagattat taggttgggg
     4681 ttaagtcagg ccctatagta aataaaagga agtgaattcc atgatcaata tcatcatttt
     4741 attggcgatc ctcggttata gtgcatgggt gctggtacga tttttgcgaa aaagccgtca
     4801 aggcgcctgt gcggggtgtt cgtcgagcaa gtcatgtcct ggctgtgccg ggagttctat
     4861 gaatgaagat accagaaaaa ctacagctgc tcacaaaggt taaccatagc atcccacaat
     4921 ggatgatgga tagtaagaaa aaaacttggt gactgctctc caaatacatt aaaggagaac
     4981 agtcaccaag ttttttatgt gtcactctat tccttgacaa ccttctaatc aggagcattt
     5041 ataagctaat catgttgatg tgttatatat agggtttcga ggtcaattgt agatcttcct
     5101 gtatatgtta tccgaccgtt tcgaagaatg gcaacctgat ctgctaattt ctcagccaac
     5161 ccaattatat gagtagataa caaaatgact ctgccttctg tgagatactc ctgtaatgta
     5221 cttctaacaa tcatcacttg atcagggtct aatccgttcg tcggttcatc taatataaga
     5281 attgtaggtt catgcaagag cgttgaggct aatgcaaccc tctttttagt tccttgagat
     5341 aactcttcca tttttatatt ttgataatct tctaatttga atctctccag ccatttagcg
     5401 atacgtattt cgagctggtt cttcggtacc tgtcgtaatc ccccaataag ccgcatcatt
     5461 tctaatacag aaagtgcggg ataataaaag gggaattctt gtagatagcc taccattgat
     5521 ttatagtttt gattttcaaa atcgataatg gtttgattga attgaattgt acctttttgt
     5581 acctgatgaa gaccagcaat taaacttaat aaggttgatt tccccgctcc attgggaccg
     5641 agtaacacag taatttggtg gtctgaaaca ttccaattta tttcatgtag aatttcttta
     5701 gagccataac cgaaagaaac ttgatccagt tgtaaaaatg gtgatttatt ttcttgggtc
     5761 atcgttgact cactcctaag atacttttct ataaaaaaag atgaatctta tatagatcat
     5821 aatagatata actgcgaata atactttatg aaattgatga agatacaata gtaatagcat
     5881 gctcattgca atgacccagt tcccgaaaaa cttgattcgg taatttccta aataatcaat
     5941 ggatataaat ttgtaaccca aaggcatacc aaaactaatt aaagtaattg aaaggaatac
     6001 attccatata atttggatta ataaactcat cggactaata tgtaaataaa ttccccaaac
     6061 ccactgatgc atagaaataa ttcctatggt tacaacacat aaaatcaacc atttggtgcg
     6121 cagcatcttc ttccaagcga ataacgttgc tttatatatt agcaatcctt tttcctctat
     6181 gataagactc ttgacagccc aaatatcaac agcaaaccat gataataccg cgctactgat
     6241 tggaagaata agcggacttt ctctaatgat ataatagttc aaaacttcaa ttcccaaagc
     6301 taaaataaaa aaagaaaaca ggttgcctcg tctaatgatg aataacaatt ctttttttag
     6361 gagtggactt tgagatagcc atccgcgtcg gttcaaattt ttttttggac catgatactg
     6421 taaaaaaaca gaccaagaac gttgtgcaaa atagagagct atatatccca tgcttatgca
     6481 taacaaaagc caagtcaaaa tacgtaccga aagagacatt ggcaatataa aatagattac
     6541 attcagtgat agaaaaaaaa agcttattgc atagccatag aattttctga ataacattat
     6601 atatccaaat atctcggcaa aaagtacacc tatgatcaat cctgaaacca tattataaat
     6661 atgattgtta tgaacacccc ataagatctg accaactacc atccataaaa gtaatattag
     6721 aaaagggact ttttttatca tagtatattg ggttagaaac aaattcccct ttcctataga
     6781 ccacaaaaaa cgtatttcct ctatttttga agtggatata cttataccaa tatgaatcaa
     6841 aaaaccactg attccatata tgatagccca catcattgct ttaaaaccca agctgtttaa
     6901 tctcaaggta acattagcta atccattggg tattagaatt aataaaagaa tgaataaagc
     6961 ggcatccatt ttagttagtt tcctgagttg attcaaatac aatatttcac ataactttat
     7021 acttgtcatt ttcctcgtct ccaagtcaca aaactgattc aaactgaaaa tcagttttct
     7081 gagaattata taaattgaaa tattgacctt ttaaatcaat taattcctga tgattacctt
     7141 gttctattat ttccccttga tcaagcacaa ttattctatc agctcgttgg attgtactaa
     7201 gacgatgagc aataatgatt tgtgtacaat gtctttcttg taagaaacct gttatcaatt
     7261 gctctgaaac actatcaagt gaacttgttg cctcatctaa aagaagaatt tgaggttctg
     7321 ccaaaaaagc acgcgccaat aaaatacgtt gccgttgtcc ccctgaaaag tttaatccgt
     7381 tctcggaaac aacagtttga tagcctaaag ggagactcat aataaaacga tgaatatcgg
     7441 cttgctttgc tgcctgaact accatatcta tggtacaatc tccattatcc atgccgatgt
     7501 tatccaatat agaaacattg aataattttg tttcttgtaa aataacccct attttttgac
     7561 gaagctcgct caaatgccat tgattcagcg ggatattatc gatgctgact tctcccaatg
     7621 aagccttata gagtcctaat attaacttcg ccaaagtgct cttacctgaa cctgaagcac
     7681 caacaattgc aaccttttca cctggcagta tttcaagatt aatatctttt aaaacgtatt
     7741 ttccaaatcg ataataatta aaggaaacat ccttaaactt aatatatcct ctaaaagtat
     7801 ggttcggttt ttgggtacct gaaggctcct ctacattctc aataacatct tgaattcgtt
     7861 gaatatatga gcccacagtg acgagttcac taagagtcga tcctaaggaa gcaatcggta
     7921 ccataaaagc agttgacaac gtttgtaagc caaggagccc ccctaaagtt atccatcctt
     7981 caaacacata atgaaatcct atccatagaa tcaggagggg aaaaacaaac tggatgctaa
     8041 ctgtcataga atcaagtgat acattccaaa tgacacgttt ttccgtagtg gcaagttgtt
     8101 ttttaaaaag ttcctcccac ttattaaata ctctattctc gaaccctaaa acttttacat
     8161 ctgtaattcc atgtatatgt tctgataaaa aaccatgcat ctcagcctgg ctcgaaatct
     8221 cctttctaga taaacggtga gtaataaatg aacttaaaac tataataagt aacattagaa
     8281 agcctacaat tgtaactatt aatccaattt gccatagttg attaatcatt aagattgcat
     8341 aagttataag taaaagccca tcaataaaaa tagttataac tcgattagat aatacccttc
     8401 taattgttac attggagtta gctctaaata ccaattctcc tccttttcga ttttcaaaga
     8461 aatcaaaagg aagtttaaaa agcttgtcta tgaattgtgt catcatagat gtatccattt
     8521 gggattgcaa cttggcaatc aagtaacctc ttaaaaattg gaataactgt gagaacacaa
     8581 atatagtaaa aatcgctccc cccaacgtga tcaggaaaga ataattttta gattctaata
     8641 agttgtcaac agtaaattgg gtgattttag gtattgaaat acctaatcct tgaagaagta
     8701 ttgagaccaa aaatacagaa ataagaagtt ttctgctctt aaaagctaat ttgatataga
     8761 acgtccattt tggtatcttt cttttattac gaaaatcctt taccgggatt aatgaaagtg
     8821 caaaacccga atatttctct gtgaattctt gaagggaaag aattagtctt ccaaaagctg
     8881 gatcaaggat tattgctttt ttctttttta ttttctcaag aaccacaaaa tgctgattat
     8941 cccataacaa aattaaagga gcggttagct catttaattg agatgccttt gcccgatatc
     9001 ctcgtgatgt taaatgatat gtactcccta tttcttgaag ttgttgcata gacatacctg
     9061 cgcgcactgc accaacctga tttcttaatt ctgttaaaga aatattatgt ccaaaaaaac
     9121 ccaaaatcat agccaaacaa gctaatccac attcactatg ttccatctgt tcaataaaag
     9181 gtactttctt attaaacttc agaggaatgc acctccatac cttccgtcaa aaaaactaaa
     9241 ccataatgat aagcaaatat gccaatctca actcttgttt ttatattcca tttctcttta
     9301 attgaagcca caatttcggc agtacgtctc atactaatag ataaatcctg ggagatttcg
     9361 ctgtctttgt atccttgagc tatacaaatt gcaacttttt gttcttttgg agataaattt
     9421 tgattttctc tcaattttta ctccccctaa gtcttttgca aatatttttt cataattaag
     9481 gaaaaatttc aatacttact taataaatat atttgtaaaa cttgaaaaaa tatattaaaa
     9541 taaaatattt ttttaattct tttagatatt tacattaaaa tgcattttta tgaagtgcaa
     9601 attaaaaaaa aatatgttta tcattaagtt tgtcttatat cactacattc ctgagaggag
     9661 taaagaataa tgacaaaaca agaaatgatc caagcatgga aaaatccaaa gcttcgtgta
     9721 gctggagaag gtattgatca tcctgcaggt gacgctttgg tcgagttgag cgctgatgag
     9781 cttgctcgtg tacatggcgg tttaggagtg caaccagatt ctactccaac tattactgtt
     9841 actgttattg gtgtcacagt actagtttgc tttccagggc atgctggata aaataagtgg
     9901 atgccactta ggaatacgcc ttaattggcg tattcctaag tattttattt cttaaaaaaa
     9961 ttgagttttt taacttcaca taaacgagga cggggtattt atgaaagagc agatcatgcg
    10021 tgctctcttt ttacatgaac gtaagaacct tgttgatcaa gcctttcaag gttttaatta
    10081 taaaaattgg agacaagata aagaaaagac aatagaacta atagacgaat ggtttaagtt
    10141 tgctctaatt agtacagaat ccaaaaagga agctcggttt aaagcttcaa gtatgaatga
    10201 agagatattt ggagccttga ttcaatctac cgaaaatctt aaatgggatg agaactattt
    10261 agcgataatc aaagagtatc aagcagattg gtttcgagtt ttggaagaag ctctaaaaat
    10321 gaatgaaaat cacccagttt tacaaaatga gtctcgaacg atgaatgttc ttattcgtcc
    10381 atttataatt tgggcgagaa atcaattaaa acagcactta tcaaaaattg ataatgccca
    10441 ggattttatt ttacatgaga atacgataaa ttcggtcttg catacattgt cttttcaatt
    10501 aacccaaatc gcaggtcggt catttgtttt agagctaaat atagctaaaa ctttggaaga
    10561 gttagaaggg caaacaccgg aggaacgatt tatctccttc attgaaaaaa aatttgtagg
    10621 acataaacaa cttgtatcat ttttttctga gtatgcagtt attgcccgca ctttggctga
    10681 aagaactatg ctttttgtaa atgtaataaa agagacgtta gaccgttatc tcttaaacag
    10741 atctatgatt atcgatatat tttctttaca ttcatcagaa ctcatacgta tcgatgctgg
    10801 tttcggtgat tctcatcagc aaggtcgcac agtaatgcgg ttatatcttg caaacgggca
    10861 atcgtttatg tataaaccaa agccattaga tatctcactc cattttcaag cattaattca
    10921 atggtttaat gataaaggtt tttctccttt tctccaaaga aactctgtta tcgcactaga
    10981 aggttatggt tatgaaaaat ttatcgaagc aaagccttgc aaaactgaag aagaaatcca
    11041 atgtttttat acacgtttag gagcgctttt agccattata tatttactgg atgggaccga
    11101 ttttcattat gaaaatttaa ttgctttcgg ggagcatcca atgctgattg atttggaaac
    11161 cctctttcac aaccaggtat atcataatgt ccccgattcc gcagatatag aagctcagtt
    11221 taggattcgt aattctccat taggcacttc actccttcct atcttgtttc atcaagatga
    11281 taaaggattt ggaattgaat taagcggtgt aaatggagaa aagcaaatga caccttaccc
    11341 ggttttgagt ttagtagatg taaatactga taatatgaga tacattagga aatctcaggc
    11401 cacttcaacg ggtaacaatc gcccttcatt agagggagaa ttaaaaaatg caggtgacta
    11461 tactaccgaa attgtaaatg gtttccaatt attatgttcc atgcttctcc aatacagaat
    11521 ggatttgtta gccccaacaa gtcctctctt tacttttaag gatgcgccag tgcgtatcgt
    11581 attacgttca acacaatttt atacaaattt tcttctcgaa tctcgtcacc ctgattatgg
    11641 tcgcgatgct ctaaatcaag agaatttact tgatcggatt tggttttcat ggttggatga
    11701 tcgaattatt tcttcagaac tacaagattt acgagtagga gatattccgt attttaccag
    11761 taaacctagt tctcttgacc tttgggatag ctatggcaaa tgtataaaag atgtgtttac
    11821 ccgaacaagc atgtcaatag tagaagatcg actgaaatct ttaactactg acagtatttc
    11881 tttatatagc gattggattt cttcttccat agcaggttca tcattaggaa aacatgtaca
    11941 taaagtgcat gatccctctc caaatgaaaa agtaatgatt aacggttaca gtccaaaacc
    12001 attacactct gaaaaattcc ttgagacagc aagaatcctt ggcgatgagt taattaaaaa
    12061 atctgttttt agtccaagca aaaagtatgt aacttggatt ggaatgaact taaattatcg
    12121 tggacagctt tatttgtccg ccttaagccc tggattatat gatggtacag caggcattgc
    12181 attatttctg gcttatctcg gaaaaatctc agaagatgaa aaatatacta gtgtagctct
    12241 cgctgcatta gaaacagcac taagtaaaat acctgtacac ttaaagttcc catctgcctt
    12301 ctatggtcaa gcttctctct tatatattct gtctcatttt gagaacctat taggttttaa
    12361 cgatgcttgg agcaagcgaa aatcggacat tataaataat ttggatgata gcgtagaaga
    12421 ggatgctttc tttgatctct taggaggatc ggcaggtgtt attcacgttc ttttaaatga
    12481 atataaccat acaaaatcgg caaagactct agaagtagca attaaatacg gagagcattt
    12541 gttaaaacac ggaataaata ataacggagt gatttcatgg atatctaatg tatctccaac
    12601 cccctatgta ggctttggcc acggtagcat tggtattgct tcagccttgt ttcgtcttgc
    12661 agcagttact aaaaaagatt gctactatgc tactgccgag aaagcattgg ctcacttaac
    12721 agaagcctat tctccagact attttaactg gattgatcat ggtaataagg agaatcatga
    12781 tcttgctaat tggtgtcatg gggccagtgg aattggcata ggactaacct tatgtatacc
    12841 ttatttaaag tccagtctag tacctggtat cgttcataat atcgaaagag cagttaatac
    12901 aactttaaaa tatggattca ataagagcca ttgtatttgt catggaagcc tcggaaatat
    12961 tgaattatta attttagccg gacaagctct taaccgtccg gagtgggtta cggaagcaaa
    13021 gaaacagggt aacaatgcgt taaattatta tttcgagcat ggtaaattta agaccggtct
    13081 gcccactgcg ttagattccc aagggctgtg gctaggtttg tctggaatag ggtatcaact
    13141 catgcgtctt tactccttaa attccctacc aagtatcctc tcactacaag agccacttca
    13201 aaaggagtcc tcttgcattt agcatcctta gaatccaaaa gccacaataa aggttatccc
    13261 taatgaggac accttaattg tggcttttga taacgtaaaa agtgaatttg atttattcct
    13321 gccccaagca gtaccctact cagcgatata ccgccaaatg ctcacttagc tctcgcgtgt
    13381 gcaagtaaac ttcacggtac agctcgtata ggccttcata ctgtgccaca cgttccgggt
    13441 tcggggaata tctcgctgct tcgcgcagaa aagcttcagc gcacgcttgc agagattcaa
    13501 accagccgct accataagca gccagcatgg ccgcccccag ggcaggtccc tgctcactct
    13561 ccagcttgat gatatccgcg ttaaaaatat ctgcctgcat ttgcagccat gcctcattac
    13621 gcgcaccgcc gccgatggaa atcacttcat tcaccgtttt gcccgttcct ctgagaatat
    13681 caatggattc cttgagcgag aacgtaattc cctccagcac cgcccgtgta aaatgcgcca
    13741 gcttatgccc cgcatccatc ccgataaagc tgcctcgaat ggtggcatcc ggatgagggg
    13801 tacgttcgcc gacaatataa ggcgtaaaca gcagcccgcg gctacccggt tcaaccgagt
    13861 ctacaccttc caacagcgca tcaaaggaat gctccggtgc aaaggtatcc ttaaaccagg
    13921 tcaagctgta tccggccgcg agcgtaaccc ccataatata atatgcatcc tgctcactat
    13981 gattaaaaaa atgcgcccgc ccttgcacat caatatcctt gcgttcctca taggaaagta
    14041 caacccctga ggtgccgatg ctgcacaggg tgcggccttc gctcaaaatg ccagcgccaa
    14101 tcgcgccaca tgcgttgtcc gcaccacctg caaagacctt cgtttcaggc gaaagcccgc
    14161 tctgctccgc aatctccggc agtagcgtac ccgtctgatc aaaggattcc accagcggcg
    14221 ggaacagcga taacggtaga tcaaacgcgg cagcgatctc ttcgctccac tgcttgttcg
    14281 caatatccag cagcagcgtg cccgccgcat ccgaatactc cgtcgccagc tctcctgtca
    14341 gacagtagcg cacataatcc ttgggcagca taaaatgtgc cgcacgggcc agcacgtctg
    14401 gctcatgctc ctgcacccac agcagcttgg gcagcgtgaa gccttccagc gcgcgattac
    14461 gtgcgatttt cagcagcttc gatccgagct tttcttcaat acaacggcat tgtgctgttg
    14521 tacgcgtgtc attccacaga atagccggac gaagcacttg gccttccttg tcagtcagca
    14581 caagcccgtg catctgtccc gaaaagctaa taccgtctac ggcatctgtg ccgccgattc
    14641 cagccttctc cacaagctgt ttcagtgatg ctaacgtgcc actgacccag tcctcaggat
    14701 gctgctcgct atagcctgcc tttggctgat gaagcggata agactgagag gtttcataag
    14761 ccacctgtcc cttgcggtta accaataccg ttttgaccgc gctggtaccc agatctacgc
    14821 cgatgacata gcgctcctgc tcctgattta gcttctcctg cattggagtt cctccttccc
    14881 tcttatcgtg cagcccttat ttcatatata agttctgaca ttagtcagcc aaaatgtatt
    14941 gatttaattt tgctttcaga tattcttggc gaccggatac gtttttacgt ggtgtttcgt
    15001 tcgccagagc atattcagcc agagaagcaa gcgttgcttt tccggatacg atgtctgctc
    15061 caataccttc tttaaagctg ctgtagcgct tctcaataaa gtcttcaaac acacgatcct
    15121 cgatcagttt agcggctacc ttcagtcctt tcgcatacgt atccatacct gcgatgtgcg
    15181 caaggaacaa gtcttccggc tcaaatgatg ctctgcgcac cttggcatca aagttgatac
    15241 cgccacggcc caagccttca ttttgtagca cttcatacat ggttagtgtg gcatcataca
    15301 gatcaaccgg gaattcgtcc gtatcccagc ccagcagcaa atctccctga tttgcatcca
    15361 gtgatcccag catgccgtta atccgtgcta cacgtacttc atgatcaaaa gtatgacccg
    15421 ccaaagttgc atgattagct tccagattaa gcttgaaatg ctgatccagg tcatattttt
    15481 gcaggaaggc aatcgtcgtc gccgcatcaa aatcatactg atgcttcgtt ggctccttcg
    15541 gttttggctc aatcaggaac tgagcgtcaa agccaatttc acgcgcatag tctacggcca
    15601 tatggaacat acgtcccaaa ttgtcctgct ccagcttcaa atccgtgttc agcagtgttt
    15661 catagccttc acggcctccc cagaaaacat agttatctgc gcccagacgt ttgccaactt
    15721 ccaatccttt tttaatctga gcagctgcgt gggcgtatac atctgcattg caagtcgagg
    15781 cagctccatg caaataccgt ggatggctaa acatgttcgc cgtgttccac agcagttttt
    15841 tccccgtagc tttcatatgt tcctcaatca ggtccacgat ggtatccaga ttgctgtaaa
    15901 attccttcaa tgacgcacct tctggtgcaa tatccacatc gtggaaagca aaataaggta
    15961 aattcagctt atccagtagc tcaaaggcag cctccacacg ggccttcgcc aaatccagcc
    16021 cggtaaactt ggaccatgga cgttccgctg tttctacacc aaaaggatcg gagccgcctg
    16081 caaccagtgt atgccaatag gccatgctaa aacgcaaatg ctcttccatc gtttttcccg
    16141 ctacaatttc ctgtggatta taaaatttga acgcaaaagg attagtggat tgcttgccct
    16201 caaagttaat tttagatact tgttcgaaat aagccattat aagttcctcc tttatagtaa
    16261 ccgtttacaa aaaagattct agcacagcta aaagactttg tctattgctt aaactaagtt
    16321 agtttttatg atataatatc gggaattaca tcaacaggaa gtgaaataaa ccatgaatgt
    16381 cactggcgat caggcgcttg tcaaaaagct gaataaatcc attgtgctgg agcgtattcg
    16441 ccttcatgct ccgctatccc gggcacaatt atccagtcaa actggattaa acaaggccac
    16501 cgtttccaat ctggtagcag agctcatcac cgatggactt gtgtatgaga cgggattagg
    16561 ggaatccagc ggcgggcgta agcctttaat gctgctgttt aacagccgtg caggctttgt
    16621 actcggtatc gaggtcagcg tacagtacat caagggtgct ctgactgatc tggcaggtac
    16681 cattgaaact gagcttgccc tttccctaac tcagcatgat cccgcctttg ttatggaaca
    16741 gattcgaaag ctcgttcagg agctcatgca ggccactcct ccctcccctc acggtattgt
    16801 cggcattggg ctgggggtgc cgggtatggt ggatgaaacc ggaaccgttt tgttcgcacc
    16861 caatctgggc tgggaagagg ttccgctgcg gcagcagctt gaggccgagc tagatctgcc
    16921 cgtcgtagtg gataatgagg ccaacgtcgg cgcgcagggc gagctgtact atggtatgga
    16981 cggcgatcac cgacagcagg tgcgggatct ggtctacatc agtgcagggt ccgggatcgg
    17041 ggccgggatt atcattgacg gcaaaccgta tcaaggagct tgggggtacg ccggagagac
    17101 gggtcatatg accattgatt ggaacggacg gctctgctcc tgcggtagtc gcggctgctg
    17161 ggagctctat gcttcagaga aggcgtatgt agcatccaca ttgaaactac ctgcacataa
    17221 tacagcggaa ttactgccgt ttgctcagca aggtgaagca agtacattaa gcgtccttga
    17281 tgatattggg cgatatttgg gtgtgggtat taccaacatt gtgaacagcc tcaaccccgg
    17341 aatgcttatc atcggcggtc cactggcgga agccagacct tggttggagc aaagtatgcg
    17401 tgatgtgatt gacgaacgtg ccctgcccta tcaccgtcgg caactacaga ttcgtttctc
    17461 cacgcttggc agtcgttcga cgatgctagg tgccgcctat gcggcaaccg ctccttttct
    17521 cgggcgagta cgcgtgtctt tataaaaggc aaaaaaataa gaccctcacc acagtcgtaa
    17581 ctgcagtagg ggtcttattt aaaccatatg acgatcatag gaccgtcata tgctgttagg
    17641 ttggattaag cgttcaacac tttttcaaac ttggttttgt tcataccgga aatacgttct
    17701 tccccgatca aagtcaatgg aacggcacga atgcccatat cccaaacctc ttgtgcaaaa
    17761 gcttcattgg tttcaatgtt gcgttcttcg tactctacgc ctttttcact caaatagctt
    17821 tttacttgac ggcaatgcgg gcagtttgta gatgtgtata ctattgcttt ttccatgaat
    17881 atcacctcat catttatttt gttacaacat atttattcat atttccaagg atcattacag
    17941 ggccagtgcg ctgtgctcca ggctttcgat gtacttctcg ctgtccatag cagccatgca
    18001 gccactacct gctgcggtaa tcgcttgtct gtagcgagta tcctgtacgt caccacaagc
    18061 gaatacgcca ggcacgtttg tttcggaagt acccggattt acgacgatat aaccgttcgc
    18121 atccgttgta atttgcccct cgaggaagcc tgtattcgga tgatgaccaa tcgccacgaa
    18181 tacgccgcta actgtaatga tctcctcttc gcctgttgca ttattcagta ctttcaagcc
    18241 agtgactccg ttctcgtcag cgatcacttc tacaggagta cgattaagtg cccattcaat
    18301 tttgttgttc gcacgagcac gatcctgcat aattttggag gcgcgcattt cttcacgacg
    18361 atgcaccaac gttactttag aggcaaaacg agtcaggaaa ttggcttctt ccaatgcaga
    18421 gtctccgccg ccgataacaa caatttcttt gccacggaaa aagaagccgt cgcatgttgc
    18481 gcaagtgctt acgccacgtc cgatattatc ctgttccccg ggaataccca ggtacttggc
    18541 agtcgctcct gtggaaataa tcagcgtatc ggtaaccagt tcacccaaac cctctacatc
    18601 caaagtaaat ggacgagccg ttgtgtctac tttgtttacc cagcctgtgc ggaattcagc
    18661 gccaaaacgc tccgcttgct tacgcatatt atccatcaaa tcgggtccca tgattccttc
    18721 aggaaagcct gggaaatttt cgacttccgt agtcgtagtt aattgtccgc ctggctgtgg
    18781 tccttcgatc accagtgggc tcatgttagc gcgtgccaga taaattgcag cggtcaaacc
    18841 ggcagggccg gtacctataa taatggactt gtacatatct tggttcctcc taaaatatca
    18901 taagtattat ataacgagtt ttcggcaccg ggcgctgggc tactgcatat actctaaaag
    18961 taattccacc agaagcttat cccaaaatgt ggacacccgg atattgcaaa aacgaatcac
    19021 ttgttttgta gcttcttatg acttagactg attctaaatc ctaatttcat tatgcggaaa
    19081 tagctgtaaa cagtcaaatg aagttttcat gaagcgaagc ttaaagataa atcaggtatg
    19141 gagggattat cccgattatg aatgacgttt ttgtaggtag ctttatttct gccctgtcca
    19201 ctggactcgg cgctgtgccc atactgttta tgcgcaatat cacgcatcgg cttcgcgatg
    19261 ttctgttggc ttatgccgca ggaattatga cctctgcatc cgtgtataac ctcattcccg
    19321 aagcaatcca gcattccaat tggttcgtgc tgactgcggg aatcctgctc ggctgcctcg
    19381 tattactggt gatggaaatg tacattcccc atgcggattt ggaggaccca gactccaaga
    19441 cctttcaact ggagtccaaa tcttttctca ttatcgcagc tattacattg cacaatttgc
    19501 cagaaggact ctctgttggg gtcagctatg caagtgaaac tcaaaatctc ggcaatctca
    19561 tcgccttctc tatcggcctg caaaatgccc cggaaggctt tatcgtagcg ttgttccttg
    19621 tgaatcaaaa tatcggccgt ttcaaggcct tgggcattgc taccctcacc ggagccgtgg
    19681 aaatcataac gagtctgatc ggcttttatt tgagcagctg ggtgaacgga ctggtacctt
    19741 acggccttgc ttttgccgcc ggagctatga tgtttatcgt ctacaaggaa ctgattcccg
    19801 agagtcacgg ggatggcaac cagcggatcg ccacattctc ttttattctc ggcttaatta
    19861 cgatgattgg gctaaccgaa tggctatagc cgagaaacac aaaaaggctg ccttctgcct
    19921 gtaatccaga cagataagca gcctttttag catgttcaca tggagatacc tcattttttt
    19981 tggttcatgg agcgcagtgc ttcacggtac tgctcgtcct cacttttgtg agtctccttc
    20041 tttccattgg ataattggga acgtccatcc ttttcttctt ccttcctggc aaaaccacgt
    20101 aaagccgcac gataatcctg atctccgtaa gcatctttga tgttctcgcg atccttttcc
    20161 accttcttat ccgtctggat atcaggcacc ttgtgttgtt cctccgcatg atgttcttcg
    20221 acgtcgatat ccttatgcgg catctctcgc gtaggatcta tcctttcacg cgcctcgggt
    20281 tccacctgta caggataagg acgtttgctt ctttgccgtg actcctcttc cgtggggcga
    20341 gttttgggag aggatttgcg cgtcatcttc gtattaaata ccagcaaaaa aataaaggca
    20401 accgcagcta ctacgataaa agcaatggtc atcggcggcc tcctattctc tttcagcgct
    20461 acggtaccgt cccgctatct cagcgacccg tttgcccaaa gaacgaccta gtgcaagatc
    20521 atcacccgtt ggaagattag gcggaccatt ggggtctgtc tccactggac atgttacgcc
    20581 tacgccgtaa taggagccgt ataatgcatt ttccgtaata ttagcgggca gtcctacaat
    20641 aatcatgcct tgatgaagca tcggagtaat caaattcaga agtgtggatt ccaatccacc
    20701 atgaacggta gcggttgtgc aaaacacagc gccgatttta tccactagct tgccctgcgc
    20761 ccacagatac cccagcttat caatccagct tttcagagcg ctgctgatgg taccaaaatg
    20821 gcccgggcaa ccccatataa ttgcatccac actcactagc tcattcacat cggcctcatt
    20881 cacatgcttt aacaacactt ccgtatgctc aaggtgtgct ccttctgcga tcgagcgagc
    20941 gagacgttcg gtatgcccat tttcactatc atatacaatc ataatcctgg tcgtcattat
    21001 gcgcatcatc ctttgtcagc aaaatcatcc ttttcgcatg cgctcttaac cttgcccaaa
    21061 atccatctga atattatgaa tcgtttgacg catactttga aaatctaaga actagggagg
    21121 catgttatac atgaattcac gcgccatatt agttaacctg ctagttatta tcattattct
    21181 ggcaggaggt ggagccgccg cctattacta caatcaatcc gccaactaca taaaaaccga
    21241 taatgcccaa gtgagcggac aagcagttac cgttgcctct ccaggcgcgg gcaagctcac
    21301 aggctggaat gccgaggttg gcaaaaccta caccgctgga agcacgcttg gtagtgttga
    21361 ggggggcgga agccgaatta gcgttacgat tccaaccgat ggtaccatcg tgcagcaatc
    21421 tgcagtcaac aactcgattg ttggggcagg tacaccctta gcgaaggctt ttgatctaaa
    21481 caatttatgg attaccgcca atatagacga aacagcagta caggatctac aagtaggaca
    21541 gacggtagat gtatatattg atgcttaccc ggatacgtcc ctgagcggta aactcgaaaa
    21601 gatcggcctg gcgaccgcat cgactttttc actactgccc acttccaata ccactgccaa
    21661 ctataccaag gtgacgcagg tcgtgcctgt caatatttcc attcaaggtt acaaggggtt
    21721 gggtattatc ccgggaatga gtgcgaccat cagagttcac aagtaggagg ctgtcatgga
    21781 tcaaaaaatg tccgtcggac gtattctgtc cgtgctgctg ctaggcgcct tcatttcgat
    21841 tttgaatcaa acgctgctta acgtggccat tccacaccta atgaatgatt tcaatgtatc
    21901 tgcaacaacc gttcaatggc tatccaccgg atatatgcta accaacggga ttctgattcc
    21961 tatcactgct tttctaattg agtcattcgg aacacgtgcg ctgttcatct ccgcgatggg
    22021 gttatttact gccgggtctg tcgtctgcgc tgccagtacc ggctttgccc ctatgttggt
    22081 tggacgcgtt attcaggcca gcggagcagg cattatcatg cctgtagtca tgaacgtgtt
    22141 cctgactgtg tttcctccgg aaaaacgggg cgccgccatg ggtaccatgg ggatcgccat
    22201 gatgtttgcc ccggcgattg gaccgacttt atccggctgg attgtggagc attacagctg
    22261 gcgactgcta tttttactcg ttattccgct ggcaatcatt gatattctgt ttgccatacg
    22321 ctggctcaaa aatgtatcca agctaacaaa accgaacttt gacctgttgg gaaccatctt
    22381 ttccacactg ggctttggct tcctgctgta tggctttagt tcagctggag acaagggctg
    22441 ggatagcaat acggtaatac ttacactcgc tgccggggtt gtgtttattg tattgtttat
    22501 cgtgcgcgag ctgaatatgg tacagccgat gctggagttc cgtgtgttta aatatgatat
    22561 ttttaccgta tcgaccttag tcggggctac cgtcaacatg acgatgtttg gcgggatgct
    22621 gctgctaccg atctatttgc aaaatatacg tggctttaca ccgctgcaat ccggtctgct
    22681 gctgttgccg ggtgcactgc tgatgggtgt gatgtcaccg atatcagggg cagtatttga
    22741 ccgtataggc gccaggccgt tggcgatcat tggactgatt attacggcag tcacgacatg
    22801 ggaattcagt ctgctgaccg atgccaccac ctacggacat attatgatca tctatacgat
    22861 tcgcagcttc ggaatgtcat tgctgatgat gtccgtccag acggaagggc taaaccagct
    22921 acctgcccat ctcggtagcc acggtacagc catgtccaac acagtacggc aaatcgctgg
    22981 gtctatcggt accgcttggc tcattactgt aatgagcagc cggaccacga ttcatgtagc
    23041 ggattatgcg aatgtcgcta ccaccgccaa tgttacttta accgaagggg tagcacagtt
    23101 gggacaaacc ctcgcgcaaa cggcgggcat ttcaacagaa agtggttcag cgttggcgct
    23161 acaacaggtg taccgaagtg ccgttacaga atcgacgatc catggcatta atgatgcctt
    23221 ta
//
