LOCUS       NZ_POVS01000021        15032 bp    DNA     linear   CON 15-SEP-2024
DEFINITION  Paenibacillus sp. F4 F4_contig_20, whole genome shotgun sequence.
ACCESSION   NZ_POVS01000021
VERSION     NZ_POVS01000021.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. F4
  ORGANISM  Paenibacillus sp. F4
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 15032)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Genome sequencing and comparative analysis of polymyxin-producing
            Paenibacillus strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 15032)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2018) Infectious Disease Research Center, Korea
            Research Institute of Bioscience and Biotechnology (KRIBB), 125
            Gwahak-ro, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-JAN-2018
            Assembly Method                   :: CLC Genomics Workbench v. 11.0
            Assembly Name                     :: F4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 524.4x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002894905.1-RS_2024_09_15
            Annotation Date                   :: 09/15/2024 04:37:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,419
            CDSs (total)                      :: 5,299
            Genes (coding)                    :: 5,203
            CDSs (with protein)               :: 5,203
            Genes (RNA)                       :: 120
            rRNAs                             :: 10, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 102
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 42 of 96
            Pseudo Genes (incomplete)         :: 67 of 96
            Pseudo Genes (internal stop)      :: 14 of 96
            Pseudo Genes (multiple problems)  :: 22 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:44:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 15032
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            POVS01000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     protocluster    1..15032
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:13391](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..13391)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(<1..4709)
                     /locus_tag="C1T21_RS25060"
                     /old_locus_tag="C1T21_25065"
     CDS             complement(<1..4709)
                     /NRPS_PKS="Domain: Condensation_LCL (48-332). E-value:
                     2.4e-110. Score: 360.2. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25060_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (501-900). E-value: 7e-125.
                     Score: 408.7. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25060_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1007-1076). E-value: 1.5e-24.
                     Score: 77.9. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25060_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1091-1375). E-value:
                     1.9e-102. Score: 334.2. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25060_Condensation_LCL.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="C1T21_RS25060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_25065"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_146032519.1"
                     /sec_met_domain="Condensation (E-value: 1.9e-94, bitscore:
                     303.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1e-130, bitscore:
                     423.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.4e-17, bitscore:
                     49.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNLMKRIESLSPEKRKLFETMLKEKGKDVSKYTPNAFSGIPSAR
                     EQEFYPMSSAQKRLYILNELEGAGTAYNMPGVVLLEGNIDAVRFEQAFKELVKRHEALR
                     TSFHMVEGEPVQKVHDYVDFSITYLELDEEKAAEIVKEFITPFDLSQVPLLRVGLVKTN
                     EDRRVMMFDMHHIVSDGISVNILMSEFLDLYQGKTLLPLRIQYKDFSVWQKEMFAGDSI
                     KKQEEYWLQTFKGDIPVLDMPTDYPRPAVQSFEGDAVSFEINPELSVKLNKLATDNGAT
                     LYMVLMAAYNVLLSRYTGQEDIIVGSPVAGRPHADLQGIIGMFINTLAIRNYPEGEKTF
                     VQFLQEVRENAFLAFENQNYQFEELVEKLNLMRDMSRNPLFDTMFALRTSNKTEFAASG
                     INFKQYNNWLEGRKAKFDLMLEVVEGQEGITFNLEYCTRLFKKETIKRFGTHYLTVLEE
                     ITACPEKRLWEIDVLLQEEKQQILYTFNATEAQYPKNKTIHQLFEEQAEKNPDHVAVVF
                     EGKKLTYSELNKKSNGLAHVLRAKGVKPDSIVGILAERSLEMIVAILGVLKAGGAYLPI
                     DPDYPEERISHMLEDSRAVILLTQSHFIDKYTSIGTVINLEDEQEYSDEQYNLSEVNKP
                     SDLAYLIYTSGSTGKPKGAMIEHRNIVRLLFNSKMQFDFNENDVWTMFHSMSFDFSVWE
                     MYGALLYGGRLVVVPKMTARSNVEYLRLLRNEKVTVLNQTPSAFYNIANEEVSYEEKEL
                     KIRYVIFGGEALKPALLKEWRKKYPQTRLINMYGITETTVHVTYKEIEEEEIRSNVSSI
                     GRPIPTLTTYVMDKNMKVVPIGVAGELCVGGDGVCRGYLGRPELTKEKFVQNPYKPEER
                     LYRSGDLVRLLSDGEMEYLGRIDHQVKIRGFRIELGEIEAQLLKHPSIEESLVIAKEDH
                     QGSKYLCAYIAGENELTISELREHLLKELPEYMVPSYFVQLEKMPLTANGKIDRKALPE
                     PEGNINTGIEYEAPIGEFEEKLALIWQDILGIKKIGRNDNFFMLGGHSLKATSLVARIH
                     KEFNIDMPLKEIFKAPIIAEIARYMKEAKESIYQSIQTAKEMEYYPMSSAQRRLYILNQ
                     FEGAGTAYNMPGSLLVEGSIDLELFQKTFQQLINRHETLRTSFHFIEGEPVQKINDPVG
                     FSVVYLESDEEKVGEIVKEFIKPFDLGIAPLLRVGLVKTGKDKHVMMFDMHHIISDGTS
                     MDILVHEFMDMYGGNNPSSLRIQYKDYSVWQKELFAGDKIKKQEEYWLQEFNGEIPVLN
                     MPVDYQRPAVQSFDGGFIRFEAGSELTGKLIKLARDNGATLYMTLLASYNILLSKYTGQ
                     EDIIVGSPIAGRPHTDLQDIIGMFVNTLAMRNYPQGEKTFAEFLKEVRENSIRAYENQD
                     YQFEELVEKLNVKRDMSRNPLFDTMFVLQNTGSSELKIDRLKFIPYTNEFRISKFDLTL
                     NARETQEGIAFDLEYATRLFKKETVERFAAHYLNVLEEITVYPGKRLSEIDMLSQEEKQ
                     KILYDFNDTKVRYPKDKTIHQLFEEQVEKTPNNIAVVFEDKQLTYKEVN"
     source          1..15032
                     /collected_by="Seung-Hwan Park (KRIBB)"
                     /db_xref="taxon:357385"
                     /mol_type="genomic DNA"
                     /organism="Paenibacillus sp. F4"
                     /strain="F4"
                     /submitter_seqid="F4_contig_20"
     region          1..15032
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..15032
                     /SMILES="C([*])C(-O)NC([*])C(=O)NC(C(O)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..15032
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[4751:13391](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(4752..13391)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     CDS_motif       complement(420..539)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0014"
                     /evalue="1.30E-18"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="1430"
                     /protein_start="1390"
                     /score="59.4"
                     /tool="antismash"
                     /translation="RENSIRAYENQDYQFEELVEKLNVKRDMSRNPLFDTMFVL"
     aSDomain        complement(585..1436)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25060_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.90E-102"
                     /label="C1T21_RS25060_Condensation_LCL.2"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="1375"
                     /protein_start="1091"
                     /score="334.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="YYPMSSAQRRLYILNQFEGAGTAYNMPGSLLVEGSIDLELFQKTF
                     QQLINRHETLRTSFHFIEGEPVQKINDPVGFSVVYLESDEEKVGEIVKEFIKPFDLGIA
                     PLLRVGLVKTGKDKHVMMFDMHHIISDGTSMDILVHEFMDMYGGNNPSSLRIQYKDYSV
                     WQKELFAGDKIKKQEEYWLQEFNGEIPVLNMPVDYQRPAVQSFDGGFIRFEAGSELTGK
                     LIKLARDNGATLYMTLLASYNILLSKYTGQEDIIVGSPIAGRPHTDLQDIIGMFVNTLA
                     MRN"
     CDS_motif       complement(588..677)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0013"
                     /evalue="7.40E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="1374"
                     /protein_start="1344"
                     /score="50.5"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHTDLQDIIGMFVNTLAMR"
     CDS_motif       complement(933..968)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0012"
                     /evalue="8.40E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="1259"
                     /protein_start="1247"
                     /score="15.2"
                     /tool="antismash"
                     /translation="QYKDYSVWQKEL"
     CDS_motif       complement(999..1064)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0011"
                     /evalue="4.60E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="1237"
                     /protein_start="1215"
                     /score="28.8"
                     /tool="antismash"
                     /translation="MHHIISDGTSMDILVHEFMDMY"
     CDS_motif       complement(1257..1373)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0010"
                     /evalue="1.40E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="1151"
                     /protein_start="1112"
                     /score="52.9"
                     /tool="antismash"
                     /translation="TAYNMPGSLLVEGSIDLELFQKTFQQLINRHETLRTSFH"
     aSDomain        complement(1482..1688)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25060_PCP.1"
                     /evalue="1.50E-24"
                     /label="C1T21_RS25060_PCP.1"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="1076"
                     /protein_start="1007"
                     /score="77.9"
                     /tool="antismash"
                     /translation="EEKLALIWQDILGIKKIGRNDNFFMLGGHSLKATSLVARIHKEFN
                     IDMPLKEIFKAPIIAEIARYMKEA"
     aSModule        complement(1482..4565)
                     /complete
                     /domains="nrpspksdomains_C1T21_RS25060_Condensation_LCL.1"
                     /domains="nrpspksdomains_C1T21_RS25060_AMP-binding.1"
                     /domains="nrpspksdomains_C1T21_RS25060_PCP.1"
                     /locus_tags="C1T21_RS25060"
                     /monomer_pairings="Thr -> Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1980..2045)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0009"
                     /evalue="8.80E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="910"
                     /protein_start="888"
                     /score="40.0"
                     /tool="antismash"
                     /translation="YLGRIDHQVKIRGFRIELGEIE"
     aSDomain        complement(2010..3206)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25060_AMP-binding.1"
                     /evalue="7.00E-125"
                     /label="C1T21_RS25060_AMP-binding.1"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="900"
                     /protein_start="501"
                     /score="408.7"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEEQAEKNPDHVAVVFEGKKLTYSELNKKSNGLAHVLRAKGVKPD
                     SIVGILAERSLEMIVAILGVLKAGGAYLPIDPDYPEERISHMLEDSRAVILLTQSHFID
                     KYTSIGTVINLEDEQEYSDEQYNLSEVNKPSDLAYLIYTSGSTGKPKGAMIEHRNIVRL
                     LFNSKMQFDFNENDVWTMFHSMSFDFSVWEMYGALLYGGRLVVVPKMTARSNVEYLRLL
                     RNEKVTVLNQTPSAFYNIANEEVSYEEKELKIRYVIFGGEALKPALLKEWRKKYPQTRL
                     INMYGITETTVHVTYKEIEEEEIRSNVSSIGRPIPTLTTYVMDKNMKVVPIGVAGELCV
                     GGDGVCRGYLGRPELTKEKFVQNPYKPEERLYRSGDLVRLLSDGEMEYLGRIDHQVKIR
                     "
     CDS_motif       complement(2127..2216)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0008"
                     /evalue="6.20E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="861"
                     /protein_start="831"
                     /score="53.7"
                     /tool="antismash"
                     /translation="PIGVAGELCVGGDGVCRGYLGRPELTKEKF"
     CDS_motif       complement(2736..2795)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0007"
                     /evalue="3.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="658"
                     /protein_start="638"
                     /score="31.9"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGKPKGAMIEH"
     CDS_motif       complement(2979..3020)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0006"
                     /evalue="2.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="577"
                     /protein_start="563"
                     /score="17.6"
                     /tool="antismash"
                     /translation="LGVLKAGGAYLPID"
     CDS_motif       complement(3549..3659)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0005"
                     /evalue="3.70E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="387"
                     /protein_start="350"
                     /score="48.2"
                     /tool="antismash"
                     /translation="AFLAFENQNYQFEELVEKLNLMRDMSRNPLFDTMFAL"
     aSDomain        complement(3714..4565)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25060_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.40E-110"
                     /label="C1T21_RS25060_Condensation_LCL.1"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="332"
                     /protein_start="48"
                     /score="360.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVSDG"
                     /tool="antismash"
                     /translation="FYPMSSAQKRLYILNELEGAGTAYNMPGVVLLEGNIDAVRFEQAF
                     KELVKRHEALRTSFHMVEGEPVQKVHDYVDFSITYLELDEEKAAEIVKEFITPFDLSQV
                     PLLRVGLVKTNEDRRVMMFDMHHIVSDGISVNILMSEFLDLYQGKTLLPLRIQYKDFSV
                     WQKEMFAGDSIKKQEEYWLQTFKGDIPVLDMPTDYPRPAVQSFEGDAVSFEINPELSVK
                     LNKLATDNGATLYMVLMAAYNVLLSRYTGQEDIIVGSPVAGRPHADLQGIIGMFINTLA
                     IRN"
     CDS_motif       complement(3717..3806)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0004"
                     /evalue="4.80E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="331"
                     /protein_start="301"
                     /score="51.1"
                     /tool="antismash"
                     /translation="DIIVGSPVAGRPHADLQGIIGMFINTLAIR"
     CDS_motif       complement(4062..4097)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0003"
                     /evalue="9.80E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="216"
                     /protein_start="204"
                     /score="15.0"
                     /tool="antismash"
                     /translation="QYKDFSVWQKEM"
     CDS_motif       complement(4128..4193)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0002"
                     /evalue="2.70E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="194"
                     /protein_start="172"
                     /score="29.5"
                     /tool="antismash"
                     /translation="MHHIVSDGISVNILMSEFLDLY"
     CDS_motif       complement(4386..4502)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25060_0001"
                     /evalue="3.20E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="C1T21_RS25060"
                     /protein_end="108"
                     /protein_start="69"
                     /score="58.1"
                     /tool="antismash"
                     /translation="TAYNMPGVVLLEGNIDAVRFEQAFKELVKRHEALRTSFH"
     gene            complement(4752..13391)
                     /locus_tag="C1T21_RS25065"
                     /old_locus_tag="C1T21_25070"
     CDS             complement(4752..13391)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (3-426). E-value:
                     4.2e-184. Score: 604.3. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25065_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (536-823). E-value: 1.4e-104.
                     Score: 341.6. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25065_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH2 (919-1136). E-value: 3.6e-33.
                     Score: 106.8. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25065_PKS_DH2.1"
                     /NRPS_PKS="Domain: PKS_KR (1427-1621). E-value: 1.5e-61.
                     Score: 199.5. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25065_PKS_KR.1"
                     /NRPS_PKS="Domain: PP-binding (1731-1794). E-value:
                     1.8e-12. Score: 39.4. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25065_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1828-2113). E-value:
                     9.8e-93. Score: 302.4. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25065_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2281-2686). E-value:
                     4.8e-100. Score: 327.0. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25065_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (2793-2861). E-value: 2e-24. Score:
                     77.6. Matches aSDomain: nrpspksdomains_C1T21_RS25065_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="C1T21_RS25065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_25070"
                     /product="hybrid non-ribosomal peptide synthetase/type I
                     polyketide synthase"
                     /protein_id="WP_103050187.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 7.5e-91, bitscore:
                     291.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 2.1e-185, bitscore:
                     604.3, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 7e-106, bitscore: 341.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 3.1e-53, bitscore:
                     168.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.5e-76, bitscore:
                     243.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8.8e-113, bitscore:
                     364.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.4e-16, bitscore:
                     47.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKIAIIGIGCRLPGGIRGPEEFWEALTAGKDMTSDLPEGRWDLE
                     KFYDPDKSKPGKHYTCHGGFLDKIDEFDPLFFGISPREAAFLDPQQRLMLETSWEAMED
                     GGLDPAKLAGTNTGVFVAGFTLDYQAIQFKNESVESLDTHSATGMMMTMLSNRISYIYD
                     FRGPSLSVDTACSGSLVATHLACGSLLNNECNLAIAGGVSVIATPEYTIAESKGGFLSP
                     DGRCKTFDSSANGYARGEGAGVVVLKRLSDAIEDGDRIYAVISGSGVNQDGHTDGITVP
                     NGQAQENLMKEVYKKAGISPSDITYIEAHGTGTPVGDPIEANAIARVVSTDRPKDKKCI
                     VGSVKTNIAHLEAAAGVAALIKASLIIKHKQIPPHLHFKNPNPKIPFDDLCIRIPQTLE
                     PLPQPALVGINSFGFGGTNAHILLEEATDLQKEGTPEVNVNTGWPYMIPISARSEKALK
                     NYAQKYVDFINGSGESISLYDIGSMMSKKRTHHDYRLAVSASSKEELAGNLEAYIKGQA
                     RQGMSAGNVEAGKYNKAVFVYTGMGPIWWAMGRQLLEKDPVFRNMIEKCDKLTRQYAGW
                     SLLEELLADEENSRLDQPQFAQPANFAVQVGLTEVWKSLGIIPHAVVGHSVGEVASTYV
                     AGIYSLEDAMLVSIHRSRAQQKAVNKGTMLAVGLPEKEVVALLDENIKGVSMAAINSPN
                     SVTLSGDPDALEQIQKQLQDKGVFARLLKVNVAYHSYQMEPYEQELLEALKGIKSQPAG
                     IPIYSTVTGKMLTGTECDGHYWYKNVREPVRFEAAMYEMISLNYNLFIEVGPHPVLAAS
                     ISDCLSAKNVEGKKLFSIKRNENEQVSILENLGNLYALGYPIDWNKIYRYQGEFVSLPL
                     YPWQWDKYWMETQESSEFRQGKNKHKFLGRRLKTSSPIWEIELNTTYMTYLSDHKIQGI
                     EVFPGAGYVELGMACARSYFGEGFYTVEDIKFENALFLNQGVSPVVQVVLDPKTAKFEI
                     SSRIPGQDKTWTCNASGTIRKRQNIKITAKDELIQILGNCTKEYGKEVCYKTFYQMGFH
                     YGPYFQGIDKIWKGDNEALGRIEIPKILEIDSSIYGLHPAVLDACFQVTIAAVAPLNED
                     ENNEGQSFLPVGIDRVQLYGRPEPVMLCHTQMVDRKDNNLNANIRLYSEDGNLIAEILG
                     IRTKELGNSGGSDAGRVKDYLYEINWELLKSEEVDTRTAAANSGAWLIFVDHKAAGKEL
                     ANLLEKRGEECFMVYPGENFGWQYEEREIYINPRSIEDLRALFDEFSKIKTKLTGIVYM
                     WSLNILEIQEVSNTAIEKACFENLFVLKHLVQATTNLGLNFKLWVITRGAQMINRATPN
                     SAFLQSLVWGLGTVIGYHELPSNWGGLVDLDIEANAGEMEMLLKEVLGNGENQIAFRNG
                     NRLAARIDKLRIDMQHQVPVHLRPDGSYVITGAFGGIGMITAQWMVAKGARHLVLLGRG
                     EFPKRSEWNNVEPGSSLAERIEFVRKLESQGATVYIGSVDVTDEEKLAGFFKDFDKEER
                     PPIRGVVHSAGITDDQFLEVSKDETFYRVLSPKVNGAWNLHRMTEGRPIDFFILFSSVA
                     SVFGSPGQGAYATGNAFLDSLAHYRLSRGLPALSINWGPWSEVGMAARFMERDPEYYIQ
                     KSIESVTVEKGIRAMEHLVGEAVAQSVVLPILSWQTFGEKWFSPMSSPHVLKTLLQDES
                     GQQENINKSKVDVDILEDIISSPIQSRQNIVEMHIKTIVAKVLRYNPEDLSTKQPLTVF
                     GMDSLMATEIKNRMEVAFKTPVSIVELLKGSSIYDLSEQMISKLYESGKISEQDSLNMG
                     KAELERIPKVSEKEYYETSSAQKMMYIINNLEGNNIGYNIPVGILFEGGIERVALGEAL
                     KTLIQRHEAFRTSFEMIDGELVQRIQDEVDFTIEYFESEEDGVEKIIDEFVRPFDLSKA
                     PLIRVGLIEIHASRQILLLDVHHIVSDGTSIIRTFDEIVSILSGESLPAMEVQYKDFAQ
                     WQNGLFSTEVYKKQEEYWLNRFKGEIPILDMPTDYPRPVLQSFEGNRLLFDLDSHLMDK
                     LNVLSSQTGATVYMILLAALNTLMYKYSGQEDIIIGTPIAARTHFDTERILGMFINTLA
                     LRNFPEGNKAFTEFLEEVKESSLEAYENQEYRFDQFVTKLNVKRDSSRNPLFTVMFNIV
                     PSDEHIMEHRGELKYSKYPVESKTSKFDLTFQLIPDGHNTILWMEYATRLFKKETVERL
                     VQHYFNILEEITSNPEKKLSEINMLSQEEKERIIYGFNDTKVEFEHHLTVHHLFEQQTK
                     VRPDNIAVAYEGRRFTYGQINQRANRIARYMLKAGTGREEAVVVMLERGPLFVESVLGI
                     WKAGGAYIPVNPKYPTQRVLDIFKESKAAYVLTLSDYVTQQLSENYKGRIIYLDQCEKE
                     IEAESGENLDLDIDINSLAYVIYTSGSTGVPKGAMIEHLGMINHIHAEIKELCITNNSI
                     ISQNSPQYFDVSVWQFFAALTIGAQIIIYPDEIVKDVARFTNRIIEDGITVLEVVPSYL
                     ALMLECVENTGNKPEKLHYLLITGETVKSGIVRKWFDLCPNTKVVNAYGPAEAADDITL
                     YTMEAAHEGENIPVGKPIQNMNLYITDKNMNLCPIGVKGEICVSGTGVGRGYLNDPEKT
                     AHVFLEDPFREEKGIRLYKTGDLGRWLPDGNIEFLGRIDHQVKIRGYRIELGEIEAQLL
                     KHSSIKEVVAATREDPQGNKYICAYIVGESELTIPELREYLSKDLPDYMIPSYFVQLEK
                     LPLSANGKVDRNALPAPDGNINTGVDYAAPFGEIEEKLVLIWSQILGVQKIGVNDNFFE
                     LGGDSLKATNLVSRVHKEFDIEFALKEVFMGPTISAIAKSIKNRLNDTVEIEEILSMIE
                     NL"
     aSDomain        complement(4809..5012)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25065_PCP.1"
                     /evalue="2.00E-24"
                     /label="C1T21_RS25065_PCP.1"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="2861"
                     /protein_start="2793"
                     /score="77.6"
                     /tool="antismash"
                     /translation="EEKLVLIWSQILGVQKIGVNDNFFELGGDSLKATNLVSRVHKEFD
                     IEFALKEVFMGPTISAIAKSIKN"
     aSModule        complement(4809..7907)
                     /complete
                     /domains="nrpspksdomains_C1T21_RS25065_Condensation_LCL.1"
                     /domains="nrpspksdomains_C1T21_RS25065_AMP-binding.1"
                     /domains="nrpspksdomains_C1T21_RS25065_PCP.1"
                     /locus_tags="C1T21_RS25065"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(5304..5369)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0021"
                     /evalue="2.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="2696"
                     /protein_start="2674"
                     /score="38.7"
                     /tool="antismash"
                     /translation="FLGRIDHQVKIRGYRIELGEIE"
     aSDomain        complement(5334..6548)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25065_AMP-binding.1"
                     /evalue="4.80E-100"
                     /label="C1T21_RS25065_AMP-binding.1"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="2686"
                     /protein_start="2281"
                     /score="327.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEQQTKVRPDNIAVAYEGRRFTYGQINQRANRIARYMLKAGTGRE
                     EAVVVMLERGPLFVESVLGIWKAGGAYIPVNPKYPTQRVLDIFKESKAAYVLTLSDYVT
                     QQLSENYKGRIIYLDQCEKEIEAESGENLDLDIDINSLAYVIYTSGSTGVPKGAMIEHL
                     GMINHIHAEIKELCITNNSIISQNSPQYFDVSVWQFFAALTIGAQIIIYPDEIVKDVAR
                     FTNRIIEDGITVLEVVPSYLALMLECVENTGNKPEKLHYLLITGETVKSGIVRKWFDLC
                     PNTKVVNAYGPAEAADDITLYTMEAAHEGENIPVGKPIQNMNLYITDKNMNLCPIGVKG
                     EICVSGTGVGRGYLNDPEKTAHVFLEDPFREEKGIRLYKTGDLGRWLPDGNIEFLGRID
                     HQVKIR"
     CDS_motif       complement(5457..5546)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0020"
                     /evalue="2.10E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="2645"
                     /protein_start="2615"
                     /score="45.6"
                     /tool="antismash"
                     /translation="PIGVKGEICVSGTGVGRGYLNDPEKTAHVF"
     CDS_motif       complement(5955..5981)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0019"
                     /evalue="9.90E+00"
                     /label="C4_LCL_164-176"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="2479"
                     /protein_start="2470"
                     /score="-0.4"
                     /tool="antismash"
                     /translation="QYFDVSVWQ"
     CDS_motif       complement(6063..6122)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0018"
                     /evalue="5.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="2443"
                     /protein_start="2423"
                     /score="31.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGVPKGAMIEH"
     CDS_motif       complement(6324..6362)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0017"
                     /evalue="6.30E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="2356"
                     /protein_start="2343"
                     /score="13.2"
                     /tool="antismash"
                     /translation="LGIWKAGGAYIPV"
     CDS_motif       complement(6891..7007)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0016"
                     /evalue="4.90E-14"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="2167"
                     /protein_start="2128"
                     /score="44.6"
                     /tool="antismash"
                     /translation="KESSLEAYENQEYRFDQFVTKLNVKRDSSRNPLFTVMFN"
     aSDomain        complement(7053..7907)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25065_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="9.80E-93"
                     /label="C1T21_RS25065_Condensation_LCL.1"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="2113"
                     /protein_start="1828"
                     /score="302.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVSDG"
                     /tool="antismash"
                     /translation="EYYETSSAQKMMYIINNLEGNNIGYNIPVGILFEGGIERVALGEA
                     LKTLIQRHEAFRTSFEMIDGELVQRIQDEVDFTIEYFESEEDGVEKIIDEFVRPFDLSK
                     APLIRVGLIEIHASRQILLLDVHHIVSDGTSIIRTFDEIVSILSGESLPAMEVQYKDFA
                     QWQNGLFSTEVYKKQEEYWLNRFKGEIPILDMPTDYPRPVLQSFEGNRLLFDLDSHLMD
                     KLNVLSSQTGATVYMILLAALNTLMYKYSGQEDIIIGTPIAARTHFDTERILGMFINTL
                     ALRN"
     CDS_motif       complement(7056..7145)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0015"
                     /evalue="1.40E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="2112"
                     /protein_start="2082"
                     /score="40.0"
                     /tool="antismash"
                     /translation="DIIIGTPIAARTHFDTERILGMFINTLALR"
     CDS_motif       complement(7404..7436)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0014"
                     /evalue="2.80E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="1996"
                     /protein_start="1985"
                     /score="13.6"
                     /tool="antismash"
                     /translation="QYKDFAQWQNG"
     CDS_motif       complement(7728..7835)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0013"
                     /evalue="3.40E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="1888"
                     /protein_start="1852"
                     /score="35.5"
                     /tool="antismash"
                     /translation="YNIPVGILFEGGIERVALGEALKTLIQRHEAFRTSF"
     aSDomain        complement(8010..8198)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25065_PP-binding.1"
                     /evalue="1.80E-12"
                     /label="C1T21_RS25065_PP-binding.1"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="1794"
                     /protein_start="1731"
                     /score="39.4"
                     /tool="antismash"
                     /translation="IKTIVAKVLRYNPEDLSTKQPLTVFGMDSLMATEIKNRMEVAFKT
                     PVSIVELLKGSSIYDLSE"
     aSModule        complement(8010..13382)
                     /complete
                     /domains="nrpspksdomains_C1T21_RS25065_PKS_KS.1"
                     /domains="nrpspksdomains_C1T21_RS25065_PKS_AT.1"
                     /domains="nrpspksdomains_C1T21_RS25065_PKS_DH2.1"
                     /domains="nrpspksdomains_C1T21_RS25065_PKS_KR.1"
                     /domains="nrpspksdomains_C1T21_RS25065_PP-binding.1"
                     /locus_tags="C1T21_RS25065"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(8529..9110)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25065_PKS_KR.1"
                     /evalue="1.50E-61"
                     /label="C1T21_RS25065_PKS_KR.1"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="1621"
                     /protein_start="1427"
                     /score="199.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GSYVITGAFGGIGMITAQWMVAKGARHLVLLGRGEFPKRSEWNNV
                     EPGSSLAERIEFVRKLESQGATVYIGSVDVTDEEKLAGFFKDFDKEERPPIRGVVHSAG
                     ITDDQFLEVSKDETFYRVLSPKVNGAWNLHRMTEGRPIDFFILFSSVASVFGSPGQGAY
                     ATGNAFLDSLAHYRLSRGLPALSINWGPWSE"
     CDS_motif       complement(8580..8684)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0012"
                     /evalue="2.00E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="1604"
                     /protein_start="1569"
                     /score="68.6"
                     /tool="antismash"
                     /translation="DFFILFSSVASVFGSPGQGAYATGNAFLDSLAHYR"
     CDS_motif       complement(8709..8738)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0011"
                     /evalue="1.80E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="1561"
                     /protein_start="1551"
                     /score="11.7"
                     /tool="antismash"
                     /translation="PKVNGAWNLH"
     CDS_motif       complement(9012..9107)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0010"
                     /evalue="2.40E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="1460"
                     /protein_start="1428"
                     /score="49.0"
                     /tool="antismash"
                     /translation="SYVITGAFGGIGMITAQWMVAKGARHLVLLGR"
     CDS_motif       complement(9645..9680)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0009"
                     /evalue="1.90E+01"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="1249"
                     /protein_start="1237"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="MVYPGENFGWQY"
     aSDomain        complement(9984..10634)
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25065_PKS_DH2.1"
                     /evalue="3.60E-33"
                     /label="C1T21_RS25065_PKS_DH2.1"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="1136"
                     /protein_start="919"
                     /score="106.8"
                     /tool="antismash"
                     /translation="TYLSDHKIQGIEVFPGAGYVELGMACARSYFGEGFYTVEDIKFEN
                     ALFLNQGVSPVVQVVLDPKTAKFEISSRIPGQDKTWTCNASGTIRKRQNIKITAKDELI
                     QILGNCTKEYGKEVCYKTFYQMGFHYGPYFQGIDKIWKGDNEALGRIEIPKILEIDSSI
                     YGLHPAVLDACFQVTIAAVAPLNEDENNEGQSFLPVGIDRVQLYGRPEPVMLCH"
     CDS_motif       complement(10569..10631)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0008"
                     /evalue="4.80E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="941"
                     /protein_start="920"
                     /score="28.7"
                     /tool="antismash"
                     /translation="YLSDHKIQGIEVFPGAGYVEL"
     aSDomain        complement(10923..11783)
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25065_PKS_AT.1"
                     /evalue="1.40E-104"
                     /label="C1T21_RS25065_PKS_AT.1"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="823"
                     /protein_start="536"
                     /score="341.6"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VYTGMGPIWWAMGRQLLEKDPVFRNMIEKCDKLTRQYAGWSLLEE
                     LLADEENSRLDQPQFAQPANFAVQVGLTEVWKSLGIIPHAVVGHSVGEVASTYVAGIYS
                     LEDAMLVSIHRSRAQQKAVNKGTMLAVGLPEKEVVALLDENIKGVSMAAINSPNSVTLS
                     GDPDALEQIQKQLQDKGVFARLLKVNVAYHSYQMEPYEQELLEALKGIKSQPAGIPIYS
                     TVTGKMLTGTECDGHYWYKNVREPVRFEAAMYEMISLNYNLFIEVGPHPVLAASISDCL
                     SAKNVE"
     CDS_motif       complement(11037..11081)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0007"
                     /evalue="4.60E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="785"
                     /protein_start="770"
                     /score="12.7"
                     /tool="antismash"
                     /translation="DGHYWYKNVREPVRF"
     CDS_motif       complement(11436..11546)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0006"
                     /evalue="4.50E-13"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="652"
                     /protein_start="615"
                     /score="41.4"
                     /tool="antismash"
                     /translation="GIIPHAVVGHSVGEVASTYVAGIYSLEDAMLVSIHRS"
     CDS_motif       complement(11550..11609)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0005"
                     /evalue="2.50E-03"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="614"
                     /protein_start="594"
                     /score="11.2"
                     /tool="antismash"
                     /translation="QFAQPANFAVQVGLTEVWKS"
     CDS_motif       complement(11733..11789)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0004"
                     /evalue="2.30E-02"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="553"
                     /protein_start="534"
                     /score="7.8"
                     /tool="antismash"
                     /translation="VFVYTGMGPIWWAMGRQLL"
     aSDomain        complement(12114..13382)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25065_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="4.20E-184"
                     /label="C1T21_RS25065_PKS_KS.1"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="426"
                     /protein_start="3"
                     /score="604.3"
                     /tool="antismash"
                     /translation="IAIIGIGCRLPGGIRGPEEFWEALTAGKDMTSDLPEGRWDLEKFY
                     DPDKSKPGKHYTCHGGFLDKIDEFDPLFFGISPREAAFLDPQQRLMLETSWEAMEDGGL
                     DPAKLAGTNTGVFVAGFTLDYQAIQFKNESVESLDTHSATGMMMTMLSNRISYIYDFRG
                     PSLSVDTACSGSLVATHLACGSLLNNECNLAIAGGVSVIATPEYTIAESKGGFLSPDGR
                     CKTFDSSANGYARGEGAGVVVLKRLSDAIEDGDRIYAVISGSGVNQDGHTDGITVPNGQ
                     AQENLMKEVYKKAGISPSDITYIEAHGTGTPVGDPIEANAIARVVSTDRPKDKKCIVGS
                     VKTNIAHLEAAAGVAALIKASLIIKHKQIPPHLHFKNPNPKIPFDDLCIRIPQTLEPLP
                     QPALVGINSFGFGGTNAHILLEEA"
     CDS_motif       complement(12429..12476)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0003"
                     /evalue="2.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="321"
                     /protein_start="305"
                     /score="13.2"
                     /tool="antismash"
                     /translation="YIEAHGTGTPVGDPIE"
     CDS_motif       complement(12669..12707)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0002"
                     /evalue="7.20E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="241"
                     /protein_start="228"
                     /score="12.7"
                     /tool="antismash"
                     /translation="FDSSANGYARGEG"
     CDS_motif       complement(12849..12896)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS25065_0001"
                     /evalue="8.30E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="C1T21_RS25065"
                     /protein_end="181"
                     /protein_start="165"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GPSLSVDTACSGSLVA"
     gene            complement(13384..14664)
                     /gene="ectB"
                     /locus_tag="C1T21_RS25070"
                     /old_locus_tag="C1T21_25075"
     CDS             complement(13384..14664)
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0047307 - diaminobutyrate-pyruvate
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (21-356). E-value: 9.4e-71.
                     Score: 230.5. Matches aSDomain:
                     nrpspksdomains_C1T21_RS25070_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013918807.1"
                     /locus_tag="C1T21_RS25070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_25075"
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_103050188.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.9e-78, bitscore:
                     250.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIFEQYESNVRAYCRNFYDVFDRAKGALIYSESGKKFVDFFAGA
                     GALNYGHNNEYIKQKILAYLESDSITHGLDMYTKAKREFIEKFSQIILEPRKLNYKIQF
                     CGPTGTNAVEASLKLARKITKRTGIFAFMGGFHGMSLGSLAVTSNIQKRSSSGIALSDV
                     TFFPYSESPIDSFDTIEYMEAVLNDGHSGIEKPAAIIFETIQAEGGVNIASPEWMLRLR
                     ELSDRHGILLICDDIQVGCGRTGPFFSFERAGMIPDIVLLSKSISGYGLPMSILLMKPE
                     LDVWKPGEHNGTFRGNQLAFIGATAALEYWEMNNLEQSVKYKEAFVREYLTKQILSLHK
                     GLTIRGAGLIWGIDFSNVEDERITQKVVEECYQNGLIIESAGRKDSVIKLMPPLTIELE
                     LLQQGCSIIRQTIQENINKVLEVESYG"
     aSDomain        complement(13597..14601)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS25070_Aminotran_3.1"
                     /evalue="9.40E-71"
                     /label="C1T21_RS25070_Aminotran_3.1"
                     /locus_tag="C1T21_RS25070"
                     /protein_end="356"
                     /protein_start="21"
                     /score="230.5"
                     /tool="antismash"
                     /translation="FDRAKGALIYSESGKKFVDFFAGAGALNYGHNNEYIKQKILAYLE
                     SDSITHGLDMYTKAKREFIEKFSQIILEPRKLNYKIQFCGPTGTNAVEASLKLARKITK
                     RTGIFAFMGGFHGMSLGSLAVTSNIQKRSSSGIALSDVTFFPYSESPIDSFDTIEYMEA
                     VLNDGHSGIEKPAAIIFETIQAEGGVNIASPEWMLRLRELSDRHGILLICDDIQVGCGR
                     TGPFFSFERAGMIPDIVLLSKSISGYGLPMSILLMKPELDVWKPGEHNGTFRGNQLAFI
                     GATAALEYWEMNNLEQSVKYKEAFVREYLTKQILSLHKGLTIRGAGLIWGIDFS"
     misc_feature    complement(14744..14759)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.32"
                     /tool="antismash"
ORIGIN
        1 tcgtttactt ccttataagt cagctgttta tcttcaaaca ctacagcaat attattgggt
       61 gtcttttcta cctgctcttc aaacagttga tgtatagtct tatccttagg ataccggacc
      121 tttgtatcgt taaagtcata tagtattttc tgcttttctt cctgtgaaag catatcaatt
      181 tctgacaacc tttttccagg ataaaccgtt atctcttcca gaacattaag gtaatgggct
      241 gcaaaccttt ctacagtctc tttcttgaac agccttgtgg catattccaa atcaaatgca
      301 ataccttcct gggtttcccg agcatttaat gtcaagtcaa atttggatat tctaaattca
      361 tttgtatagg gtataaactt aagcctatct atcttcaatt ctgatgagcc ggtattttgc
      421 aatacaaaca tagtatcaaa aagaggattc ctgctcatat ccctctttac attaagcttt
      481 tccaccagtt cttcaaactg gtagtcctga ttttcataag cccttataga gttttccctt
      541 acttccttta gaaactcagc aaaggtcttt tctccctggg gatagttcct catggctaaa
      601 gtatttacaa acatacctat tatgtcttgt aaatctgtat gaggtcttcc agctataggg
      661 cttcccacta taatatcttc ctgccccgta tacttagaca gcagtatgtt gtatgaagca
      721 agcaatgtca tgtaaagagt agccccatta tcccttgcaa gcttaataag ttttcccgta
      781 agctcactgc ctgcttcaaa acggataaaa cctccgtcaa agctttgaac cgcaggcctt
      841 tggtaatcta ctggcatatt cagcacagga atttctccat taaattcctg gagccagtat
      901 tcctcctgct tctttatttt gtccccagca aatagttcct tctgccaaac agaatagtcc
      961 ttgtactgta tacggaggga agaagggtta tttcctccat acatatccat gaactcatgt
     1021 accagtatat ccatggacgt accgtcagat atgatatggt gcatgtcaaa catcatgaca
     1081 tgcttgtctt ttcccgtttt cacaaggcct actcttagca gcggagcaat tccaagatca
     1141 aacggcttta taaattcttt tacgatttcc cccacttttt cttcgtcaga ttctagatac
     1201 actacactaa aacccacagg atcattgatc ttctggacgg gttcaccctc tatgaaatgg
     1261 aaagatgttc gaagggtctc atgcctattt ataagctgtt ggaaggtctt ctgaaaaagc
     1321 tccagatcaa tactgccttc aaccagcaag ctgcctggca tattgtatgc tgtccctgct
     1381 ccttcaaact gatttaatat atacagcctt ctttgggctg atgacatagg gtagtattcc
     1441 atctctttag cagtttggat ggattgatat atactctcct ttgcttcctt catatacctt
     1501 gctatttccg ctataattgg agccttaaat atttccttaa gaggcatgtc tatattgaac
     1561 tctttgtgaa ttctcgctac aaggcttgta gcctttaaag agtgtccacc taacataaag
     1621 aagttgtcat ttcttcctat cttcttaatt ccaaggatgt cttgccaaat cagtgcaagc
     1681 ttctcttcaa attcgcctat aggcgcttca tactctattc ccgtatttat attaccttcg
     1741 ggttcaggca atgccttcct gtctatcttg ccattagctg tcaatggcat tttttcaagc
     1801 tgcacaaagt atgatggtac catgtattcg ggcagttctt ttaagagatg ctcccttagt
     1861 tctgatattg tcagctcatt ttctcccgct atatatgcac acaggtattt actgccctga
     1921 tggtcttcct ttgcaatcac caaagattcc tcaattgaag gatgctttag cagttgtgct
     1981 tctatttcac caagctctat cctaaagcct cttatcttta cctggtggtc tattctaccc
     2041 aggtattcca tttctccatc agataataac cggaccaggt ctccagatct atataacctc
     2101 tcttccggct tgtacggatt ttgaacgaac ttttcctttg taagctccgg tcttccaaga
     2161 tatcctctgc aaactccgtc tcctcctaca caaagctctc cggctactcc aatgggaaca
     2221 actttcatgt tcttatccat tacatatgtt gtaagggttg gtataggcct tcctatgctg
     2281 ctcacattag atctaatttc ttcctcttct atctctttat atgtgacatg cactgttgtc
     2341 tcggttattc catacatatt gatgagtcta gtctgcgggt acttctttct ccattccttc
     2401 aacaatgcag gctttaatgc ttcccctccg aatatgacat atcttatctt aagttctttt
     2461 tcttcatatg atacttcttc attggctata ttatagaagg ctgaaggtgt ctgatttaat
     2521 acggtcacct tctcattcct tagaagtctc agatactcta cattgctgcg tgctgtcatt
     2581 ttaggaacta ccaccaatct gcccccatat aacaacgccc cgtacatctc ccatacggaa
     2641 aaatcgaaac tcatagaatg aaacatagtc catacatcat tttcgttaaa atcaaactgc
     2701 attttactgt taaataacag ccttactatg tttctatgct ctatcattgc ccctttgggt
     2761 ttacctgtag agcctgaggt atatattaag taagctagat cggaaggttt atttacctcc
     2821 gataagttat attgttcatc tgaatattcc tgctcatctt ctaaatttat tactgtacct
     2881 attgatgtat atttgtctat aaaatgtgat tgggtcaaca ggatcactgc ccggctgtct
     2941 tccagcatat gacttattct ttcctcagga taatctggat ctatgggaag atatgcccct
     3001 cctgctttta atacccctag gattgctact atcatctcaa gtgagcgttc tgccagaata
     3061 cctacgatac tgtccggttt gactccttta gcccttaata catgggccaa cccatttgat
     3121 tttttattga gttcactata tgtaagcttt ttaccctcaa ataccacagc tacatgatca
     3181 gggttcttct ctgcctgctc ttcaaaaagc tgatggatag tcttgttttt aggatactgt
     3241 gcctctgtag cgttaaaggt atataggatt tgctgttttt cttcctgtaa cagtacatca
     3301 atttcccaca accttttttc agggcatgcc gttatctctt caagaacggt taagtaatgg
     3361 gttccaaacc tttttattgt ctccttctta aacagcctgg tacaatattc aaggttaaat
     3421 gttatacctt cttgaccctc taccacttca agcataaggt caaattttgc ctttctgcct
     3481 tccagccagt tgttgtattg tttgaagttt atacccgatg ctgcaaattc tgtcttgttt
     3541 gaagtgcgca gtgcaaacat agtgtcaaaa agaggattcc tgctcatgtc cctcatgaga
     3601 ttaagttttt ctacaagttc ttcaaactgg tagttctgat tttcaaaagc caaaaacgca
     3661 ttttccctta cttcctgcaa gaattggacg aaggtctttt ctccctcagg atagttcctt
     3721 atggccaagg tatttataaa cataccaatg ataccctgca ggtcagcatg gggccttccg
     3781 gctacaggac ttccaactat gatgtcttcc tgtccagtgt atctggacag gagtacgtta
     3841 tatgcagcca tcagtaccat gtataaggta gctccattat ctgttgcaag cttatttagt
     3901 ttgactgaaa gttcagggtt tatttcaaag cttacagcat ctccttcaaa actttgtacc
     3961 gccggtcttg gatagtcagt aggcatatcc agtaccggta tatcaccctt aaatgtctgg
     4021 agccagtatt cttcctgctt ctttattgag tctccggcaa acatctcctt ctgccataca
     4081 gaaaaatcct tgtactgtat ccgtagtggc aaaagggtct tcccttggta caaatccaaa
     4141 aactcactca taagtatatt gactgatata ccatctgata ctatgtggtg catgtcaaac
     4201 atcataacac gcctgtcttc gttcgttttt acaagtccta ctctcagtaa tggaacttgg
     4261 ctaagatcaa agggcgttat gaattctttg actatttctg ctgctttttc ttcatccagt
     4321 tccaggtacg taatactgaa atccacgtaa tcatgaacct tttgtactgg ttcaccctca
     4381 accatatgaa atgatgtgcg cagagcctca tgtcttttta ctagctcctt gaatgcctgt
     4441 tcgaagcgta ctgcatcaat gtttccttcc agcagtacga cgcctggcat gttatatgca
     4501 gtacctgctc cttcaagctc gtttagtata tacagccttt tctgggcaga tgacataggg
     4561 taaaattcct gctctctggc agaaggtatt ccagaaaagg catttggcgt atattttgaa
     4621 acatcttttc ctttttcttt tagcatcgtc tcaaatagct ttcttttttc tggagaaaga
     4681 gattctattc ttttcatcaa attatccata acttcgtccc tcttctctat ttcatctctt
     4741 ttaattccta tttatagatt ttcaatcatg cttaaaattt cttcgatttc cactgtatcg
     4801 ttaagtctat ttttaatact ttttgctatt gccgaaattg taggacccat aaacacttct
     4861 tttaatgcaa attctatgtc aaattcttta tgaacccttg atacaagatt ggttgccttt
     4921 aatgagtctc ctcctaattc aaagaagtta tcatttactc caatcttctg gactccaagg
     4981 atttggctcc atatcagtac aagcttctcc tcaatttcac cgaatggtgc agcatagtct
     5041 acccctgtat taatatttcc atcaggggca ggcagggcat ttctatctac cttgccattc
     5101 gctgataaag gcagtttttc caactgtaca aaatatgaag ggatcatgta gtctggcaga
     5161 tctttggaga gatactccct taattccggt attgtcaatt cactttctcc aactatatat
     5221 gcacagatgt acttgttccc ttgggggtct tcccttgttg ctgccacaac ttcttttatt
     5281 gaagaatgtt ttagaagctg agcttctatt tctccaagct ctattcggta tccgcggatc
     5341 ttaacctgat ggtctattct gcccaggaat tcgatattcc cgtcaggcag ccatcttccc
     5401 aggtctcctg ttttgtacag ccttatcccc ttttcttctc tgaaaggatc ttcaaggaat
     5461 acatgggctg ttttttcagg gtcatttaaa taaccccttc ctacacctgt tccagagacg
     5521 cagatctctc cttttactcc gatagggcac aggttcatgt ttttatctgt tatatataga
     5581 ttcatatttt gtataggctt gcctacagga atgttctctc cttcatgagc agcttccata
     5641 gtatatagag taatatcgtc cgctgcctct gcaggtccgt aggcattaac tactttagta
     5701 tttggacata ggtcaaacca tttccttact atgccggatt ttacggtttc tcccgttatc
     5761 agcaagtaat gaagtttttc cggtttattc cctgtatttt ccacacactc aagcattaaa
     5821 gcaaggtatg aaggtaccac ctcaaggacc gttatgccat cttctatgat ccgattcgta
     5881 aaccttgcaa catcctttac tatttcatct ggatagatga taatttgagc tcctatggtt
     5941 agggctgcaa agaactgcca tacagataca tcaaagtatt gaggcgagtt ctgggatatt
     6001 atgctgttgt tagttataca aagttccttt atttccgcat ggatgtggtt tatcatgcca
     6061 agatgctcta tcatagctcc ctttggtaca ccagttgaac cagatgtata tataacatag
     6121 gccaaactat ttatgtctat atctagatct aggttttcgc cactttcagc ctcaatctct
     6181 ttttcacact ggtcaaggta tataattcgg cctttatagt tctcactaag ctgctgggtc
     6241 acataatctg ataaggtcaa cacataggca gctttagatt ccttaaatat atcaagcacc
     6301 ctttgtgtag ggtattttgg atttacaggt atgtaagccc cccctgcttt ccatatacca
     6361 agtaccgatt ctacaaataa gggtcccctc tccagcatga caactacggc ttcttctcta
     6421 ccagtgccag cctttagcat gtaccttgct atcctgtttg ccctttggtt gatctggcca
     6481 tatgtaaatc tacggccttc atacgctact gctatattgt ctggacgtac tttcgtctgc
     6541 tgctcaaaca ggtggtgtac cgtcaggtga tgttcaaatt caaccttcgt atcgttaaag
     6601 ccgtatatta ttcgctcctt ttcttcttgg gataacatat tgatttctga tagttttttt
     6661 tcagggtttg aggttatctc ttcaaggata ttaaagtaat gctgaacaag cctttctacc
     6721 gtctccttct taaacagacg tgtagcatat tccatccata atattgtatt atgaccatct
     6781 ggtatcaact ggaatgttag gtcaaatttt gatgttttac tttcaaccgg atatttggaa
     6841 tactttaatt caccacgatg ttccataata tgctcatcag aaggaacaat attaaacata
     6901 acagtaaata aaggatttct gcttgaatct ctctttacgt taagttttgt cacaaactga
     6961 tcaaacctgt attcctgatt ttcatatgct tctaaggagc tttcttttac ttcttccaag
     7021 aactcagtaa aggccttatt tccctctggg aaattcctta atgccagggt atttataaac
     7081 atccccagta ttctttcagt atcaaaatga gttcttgccg ctataggagt accaataatt
     7141 atgtcttcct gtcctgagta tttatacatt agtgtattta atgccgcaag aagtatcata
     7201 tacacggtgg ctcctgtttg ggaggaaagt acatttaatt tatccatcaa atgactgtct
     7261 aaatcaaata gcaacctatt tccttcaaag ctttgaagga caggcctagg ataatctgta
     7321 ggcatatcaa ggataggaat ttcacccttg aacctattaa gccagtattc ttcctgcttt
     7381 ttgtaaacct cagtgctaaa caagccattc tgccactggg caaaatcctt atattgcacc
     7441 tccattgccg gaaggctttc accacttaat atagaaacta tttcatcaaa agtcctgatt
     7501 attgaagttc catccgagac tatatgatgt acatcaagca aaagtatttg cctgctagca
     7561 tggatttcta taagacctac tcttattaag ggtgctttgc ttaaatcgaa cggtcttaca
     7621 aattcatcga ttattttctc tactccgtct tcctcagact caaaatattc tatagtaaaa
     7681 tcaacttcat cttgtatcct ttgcacaagc tccccatcaa tcatctcaaa ggatgtccta
     7741 aatgcttcat gcctttgtat caatgttttt aatgcttccc caagggcaac cctttcaatc
     7801 ccaccttcaa ataaaattcc cacaggtatg ttatacccaa tgttgttacc ctcaagatta
     7861 ttaatgatat acatcatctt ttgtgcagat gaggtttcat agtactcttt ttcagaaact
     7921 ttaggtattc tttcaagctc agccttaccc atatttaggg aatcctgttc tgaaatcttt
     7981 cccgattcgt atagctttga tatcatttgc tcggaaagat cgtatatgct ggaaccctta
     8041 agaagttcta ctatggaaac aggtgtttta aaggcaacct ccatcctgtt ttttatttcg
     8101 gtggccatta atgaatccat cccaaaaaca gttagtggtt gtttggtact tagatcctca
     8161 ggattataac gcaaaacctt cgctactatt gttttaatat gcatttcaac gatattctgc
     8221 ctgctctgta ttggagatga aataatatcc tccaggatat caacatccac ctttgattta
     8281 tttatattct cttgttgtcc tgactcatct tgcaaaagag ttttaagcac atgtggagaa
     8341 ctcatgggtg agaaccattt ttccccaaac gtttgccacg agagtatagg tagaaccaca
     8401 gactgtgcaa cagcttctcc aacaaggtgc tccatagccc taattccctt ttctaccgtt
     8461 acagattcta tggatttttg tatataatac tccggatcac gttccataaa ccttgcagcc
     8521 attccaacct ctgaccatgg tccccaattg atactcagtg caggaagtcc tctcgataaa
     8581 cggtaatgtg caagtgagtc caaaaaggca ttcccagttg catatgctcc ctggcctggt
     8641 gaaccaaata cagaagcaac tgaagaaaat aaaataaaga agtcaatagg ccgtccctct
     8701 gtcatacggt gaaggttcca tgcaccattt accttaggcg aaaggaccct ataaaaagtc
     8761 tcatctttac taacctcaag aaattgatca tccgtaatac cagcagaatg tacaacacct
     8821 cgaataggag gcctttcttc cttatcaaaa tctttaaaaa atccagcaag cttttcctca
     8881 tcagttacat ccactgatcc aatatatact gttgccccct gggactccag cttacgaaca
     8941 aactcaatcc tctctgcaag gctgctgcct ggctctacat tgttccattc agaacgtttt
     9001 ggaaattctc cgcgtccaag cagtaccaga tgtcttgctc ccttggcaac catccactgg
     9061 gctgtaatca tacctatgcc accaaaagca cctgtaataa cataacttcc atcggggcga
     9121 agatgtacgg gtacttgatg ctgcatatca atccgcagtt tatcgattct tgctgcaagt
     9181 ctattcccat tacggaaagc aatttggttc tctccattac ctaagacttc ttttaacagc
     9241 atttccattt cacccgcatt ggcctctatg tcaaggtcta caaggcctcc ccaatttgaa
     9301 ggcaactcat ggtaacctat gacggtgcca aggccccata ccaacgactg taagaatgca
     9361 gaatttggag tagccctgtt gatcatttgg gctcctcttg taataaccca cagcttaaaa
     9421 tttaatccca gatttgtggt tgcttgtacc aggtgtttta atacaaacag gttttcaaaa
     9481 caagcttttt ctatagctgt attgctaact tcctggatct caaggatatt gaggctccac
     9541 atatatacaa tacctgttag cttcgtttta atttttgaga attcatcaaa caacgctcta
     9601 agatcctcaa tgcttcgagg gtttatatat atctcacgct cttcatactg ccaaccaaaa
     9661 ttctcaccag gatataccat aaagcattct tctccccttt tttcaaggag atttgccagt
     9721 tcttttcctg ctgctttatg atccacaaaa ataagccatg ctccagagtt agcagcagct
     9781 gtgcgggtat caacttcttc actttttaga agctcccagt ttatctcata aagataatcc
     9841 ttaactcttc cagcatcaga ccctccacta tttccaagtt ccttagttct tatgcccagt
     9901 atttcggcga ttagatttcc gtcctcacta tatagacgga tgttggcgtt caaattatta
     9961 tctttcctat ctaccatctg cgtatgacaa agcatgacag gctccggcct tccataaagc
    10021 tgcaccctgt ctattcctac aggtaggaat gattggcctt cgttattttc atcttcatta
    10081 agtggtgcaa ctgccgcaat ggtaacctgg aaacaggcgt ccaataccgc cgggtgaaga
    10141 ccgtagatag agctatcaat ctccagtatt ttagggatct cgatcctgcc aagagcttcg
    10201 ttatcacctt tccatatctt gtctatacct tggaaataag gaccataatg gaaacccatt
    10261 tgatagaagg ttttataaca tacttctttt ccgtattctt tggtacaatt gccaagtatt
    10321 tgaatcaact catctttagc agtgatcttt atgttttgcc gttttcttat tgtgccggat
    10381 gcattgcatg tccaagtctt atcttgtccc ggtatcctgc ttgaaatctc gaattttgcg
    10441 gtttttggat ccaaaaccac ctgcaccaca ggtgatactc cttgatttaa aaataaagca
    10501 ttttcaaact ttatatcttc aactgtataa aaaccctctc caaaatagct tctggcacaa
    10561 gccattccca gctctacata ccctgctccg gggaaaactt ctataccttg tattttatga
    10621 tcagaaagat acgtcatata ggtagtatta agttcaatct cccatatagg gctggaagtt
    10681 ttcaaacggc gtcctaaaaa cttgtgctta ttttttccct gcctaaattc acttgattcc
    10741 tgcgtttcca tccagtattt atcccattgc catggataaa gagggagact tacaaactca
    10801 ccttggtacc ggtaaatctt gttccaatct atagggtatc ccagtgcata tagattccct
    10861 aagttctcca gtattgaaac ctgttcgttt tcatttcttt ttatagagaa caacttctta
    10921 ccttcaacgt ttttagctga cagacaatca gaaatagaag ctgctaaaac agggtgaggg
    10981 cccacctcaa taaataagtt ataattcaac gaaatcattt catacattgc tgcttcaaaa
    11041 cgtaccggct ctcttacatt tttataccag taatgtccat cacactctgt acccgtcagc
    11101 attttccctg taaccgtgga atatatcggt atcccggcag gctgggactt tattcctttt
    11161 aatgcctcca atagctcctg ctcatatggt tccatttggt aactgtgata cgctacattg
    11221 acctttaaaa gccgcgcaaa aaccccctta tcctgcaact gtttttggat ctgctcaagg
    11281 gcatcaggat cacctgacaa agttaccgaa tttgggctat tgattgctgc cattgaaaca
    11341 ccttttatgt tctcatccag cagggccaca acttcttttt ctggtaaacc taccgccagc
    11401 attgtgccct tgtttactgc tttttgctgt gcacggcttc tgtgaatact taccaacatg
    11461 gcatcttcaa ggctgtaaat tcctgcaaca tatgtagaag ccacttctcc aacactgtgt
    11521 cctaccaccg catggggtat aatacccaag gatttccata cttcagtcaa acccacctga
    11581 acagcaaaat tggcaggttg agcaaactgg ggctggtcca gacgtgaatt ctcctcatcg
    11641 gcgagaagtt cctccagtag agaccatcca gcatactgac gtgtaagttt atcacatttt
    11701 tctatcatat ttctaaacac agggtctttt tcaaggagct gtctgcccat agcccaccat
    11761 atgggcccca tacctgtata tacaaaaaca gctttattgt actttcctgc ctcaacattt
    11821 cccgcagaca tcccctggcg tgcttgtcct ttaatatacg cttccaggtt tcctgcaagt
    11881 tcttcctttg aagatgccga aaccgctagt ctatagtcat gatgggtgcg ctttttgctc
    11941 atcatgcttc caatatcata taaagaaata ctttctccac ttccattaat aaaatcaaca
    12001 tacttttgcg catagttttt tagcgccttt tctgagcgcg cagatatggg aatcatatat
    12061 ggccatccgg tatttacatt aacttcagga gtaccctctt tttggagatc tgtagcttcc
    12121 tccaagagga tatgggcatt tgttcctcca aaaccgaatg aatttatgcc aaccaatgcg
    12181 ggttgcggca aaggctccag ggtctgagga attcgtatac ataaatcgtc aaagggaatt
    12241 ttagggtttg gattcttaaa gtgcagatgt ggaggtattt gcttatgctt tatgattagt
    12301 gaagctttta tcagtgcggc aactcctgca gcggcctcaa ggtgggcaat gtttgtctta
    12361 acagatccga caatacactt tttatctttt ggcctgtctg ttgaaaccac tcgtgctatt
    12421 gcattagcct caatagggtc tccaaccgga gtgccggtgc cgtgagcttc aatatatgtt
    12481 atatctgaag gtgatattcc tgcctttttg tatacctcct tcattaagtt ttcctgagcc
    12541 tgcccgtttg gaacagtaat cccgtctgtg tggccgtcct ggtttacacc cgatccactt
    12601 attacggcat aaatcctatc tccgtcttcg atagcatctg acaggcgttt taaaaccaca
    12661 acgccggctc cttctcctct tgcataaccg tttgcactgg aatcgaaagt tttgcaccgt
    12721 ccatcgggag ataaaaaacc acccttactt tccgctatgg tatactcagg tgtagctata
    12781 acacttactc cgcctgctat tgcgagatta cattcattat tcaataaact cccgcatgca
    12841 aggtgtgttg caaccaaaga gcccgaacac gctgtatcta cagacaaact tggacctctg
    12901 aaatcatata tatatgaaat cctgttggac aacattgtca tcatcatacc cgttgccgaa
    12961 tgtgtatcta aactttcaac cgattcgttt ttaaattgta ttgcttgata gtcaagggtg
    13021 aagcccgcta caaagacacc ggtattggtt cctgctagct tggccggatc caagcctcca
    13081 tcttccattg cttcccatga tgtctccagc atcagtcttt gctgtggatc aagaaaggcc
    13141 gcttcccttg gagaaatacc aaaaaacaaa gggtcaaact catctatttt atctaaaaat
    13201 ccaccatgac aggtgtaatg cttgcctggc tttgatttgt caggatcata aaacttttct
    13261 aaatcccagc ggccttcggg taaatcggaa gtcatatctt ttcccgcagt caatgcttcc
    13321 cagaactcct caggccccct tattcctcct ggcaaacggc atcctattcc tataatggcg
    13381 attttatcca taactttcga cctccaatac tttatttata ttctcttgaa tagtttgtct
    13441 gataattgaa caaccctgct gcaaaagttc aagctcgatg gttaacggag gcataagttt
    13501 tataacactg tcttttcttc ctgcgctttc gatgattaaa ccgttttggt aacattcctc
    13561 tactactttt tgcgtgattc gctcatcctc cacattggaa aaatcaatac cccaaatcaa
    13621 acctgcaccc cgaatggtca ggcccttatg taatgacaaa atctgcttgg ttaaatattc
    13681 tcttacaaat gcttccttat atttcacaga ctgttccaaa ttattcattt cccaatattc
    13741 caacgcagct gtagctccaa tgaaagcaag ctggtttccc cggaacgtac cgttatgctc
    13801 accaggcttc cagacatcaa gttccggttt catcagcaga atagacatgg gaaggccata
    13861 cccgctgatt gacttggaaa gcagtacaat atcagggatc atcccggcac gttcaaatga
    13921 aaagaacggt ccggtgcgtc cgcagccaac ctgaatgtca tcgcaaatca gtagaatacc
    13981 gtgtctgtcg ctaagttccc tcagcctgag catccattcg ggtgaagcta tatttacgcc
    14041 gccttccgcc tgaatggttt caaatataat agccgccggt ttttcgattc ccgagtgacc
    14101 gtcgtttaga acggcttcca tgtattcaat agtatcgaat gagtcaattg gactctcgga
    14161 gtatgggaaa aaggtaacat cggataatgc tatgccggag gaagatcttt tctgaatgtt
    14221 gctggtaaca gccagactcc ccagcgacat tccgtgaaat cctcccataa acgcaaatat
    14281 accagtccgt ttagtgatct ttcgggcaag cttcagcgat gcttctacag cgtttgtacc
    14341 tgtaggcccg caaaattgaa ttttatagtt taactttcgg ggttccaata tgatctgcga
    14401 gaatttttcg ataaattcac gtttcgcttt tgtgtacata tcaagcccat gagtaatact
    14461 gtccgattca agataagcga gtatcttttg tttgatgtat tcgttgttat gtccataatt
    14521 taaagctcct gctcctgcaa aaaaatcaac aaatttcttt ccggattctg aataaatcag
    14581 tgcaccttta gcccggtcaa acacatcgta gaagtttcta caatatgctc ttacgttgga
    14641 ttcatactgc tcaaaaattt ccatactcat aattcctccc ttaaactgaa gttagtgttt
    14701 aaacactaac ttcagtttat ttttccggcc caatccacat ccatgttctc tcccggcttg
    14761 tggtggatgt gcatcgttgc ctttgtcctc ccccgcccac tcccggtatt acttacaaaa
    14821 ctgggtgtac atgtacggta ggattgtaaa acctgcaagg gtggaaaata aataacatct
    14881 tagttcttac cgccatagcc cttataagta gcgtaaactg catctgcata ttgattggcc
    14941 agaataggac ggccataaga gtctgtagct cccggatacc agttatctcc tccgttatag
    15001 tgtaataagc cattatatat gttgccgaat ct
//
