LOCUS       NZ_POVS01000017        22388 bp    DNA     linear   CON 15-SEP-2024
DEFINITION  Paenibacillus sp. F4 F4_contig_16, whole genome shotgun sequence.
ACCESSION   NZ_POVS01000017
VERSION     NZ_POVS01000017.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. F4
  ORGANISM  Paenibacillus sp. F4
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 640241)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Genome sequencing and comparative analysis of polymyxin-producing
            Paenibacillus strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 640241)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2018) Infectious Disease Research Center, Korea
            Research Institute of Bioscience and Biotechnology (KRIBB), 125
            Gwahak-ro, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-JAN-2018
            Assembly Method                   :: CLC Genomics Workbench v. 11.0
            Assembly Name                     :: F4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 524.4x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002894905.1-RS_2024_09_15
            Annotation Date                   :: 09/15/2024 04:37:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,419
            CDSs (total)                      :: 5,299
            Genes (coding)                    :: 5,203
            CDSs (with protein)               :: 5,203
            Genes (RNA)                       :: 120
            rRNAs                             :: 10, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 102
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 42 of 96
            Pseudo Genes (incomplete)         :: 67 of 96
            Pseudo Genes (internal stop)      :: 14 of 96
            Pseudo Genes (multiple problems)  :: 22 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:44:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 330454
            Orig. end                         :: 352842
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            POVS01000017.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22388
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..22388
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22388
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12388](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12388
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            111..1262
                     /locus_tag="C1T21_RS20165"
                     /old_locus_tag="C1T21_20170"
     CDS             111..1262
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821761.1"
                     /locus_tag="C1T21_RS20165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20170"
                     /product="immunity 26/phosphotriesterase HocA family
                     protein"
                     /protein_id="WP_103049498.1"
                     /transl_table=11
                     /translation="MNRWLTNALRPYFGLETLEEHWDVVEIKEGYFICMDGDVIRKRIS
                     STEDTYGETDVEILTRDRAFVLPKTARGKEKKLNYTSVSSIKAEGITFSTGIRRDRPLS
                     YVTAVNSKTGVKLPITGCEHLHSKEEIIDWLQQYPSLVPKDYDRRLHRLKLMKNQRYKT
                     VPGDIFRVEIDLFTDGYVLVIGDLRQMQKNQLFAEESIWNSVMTMPLFVRPYLFTSRDR
                     STALESITAAPLSETTWIVMDDSFMRGAYERVGHKLLVEEDIVFPIGYGCSTDSRKERT
                     YSLSWGTGTVSKPEGETVFKSSRKFLNNGVYSSVVADCFGSWEEREWYKMLDNPLYQDE
                     RRKALAEFGFLEDISYDEFNRQTGGLTRSEYLAYLIRIYGGKK"
     gene            1298..1513
                     /locus_tag="C1T21_RS28155"
     CDS             1298..1513
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS28155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_258012564.1"
                     /transl_table=11
                     /translation="MKYLKDCPEPGMGTWYFEIDSDGIAYRQIVIQDDGTYIASNRKHE
                     QYHFLLAEKAIDDTEPYYTQITKKRV"
     gene            1467..1817
                     /locus_tag="C1T21_RS20170"
                     /old_locus_tag="C1T21_20175"
     CDS             1467..1817
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS20170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C1T21_20175"
                     /product="hypothetical protein"
                     /protein_id="WP_258012565.1"
                     /transl_table=11
                     /translation="MIQSPIIRKLQKKEFEEIWSNYLHTFNKEWHQIKNALPVGTKVKG
                     YIEAFFPHGTLIHIFQHHAVGLSDTRTYEEKTPSEWMYPKHEVTAIVKGYDEVNQWVIL
                     DQTQVFKNQFAG"
     gene            1854..2513
                     /locus_tag="C1T21_RS20175"
                     /old_locus_tag="C1T21_20180"
     CDS             1854..2513
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688169.1"
                     /locus_tag="C1T21_RS20175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20180"
                     /product="DUF2625 domain-containing protein"
                     /protein_id="WP_103049499.1"
                     /transl_table=11
                     /translation="MHTLTVDELVDKDNHAWEEVRNILKEGRNSHHIVSAESESATGDT
                     LYRLQVSTKSYLGTVAYETGGIVFDYGWITLLGAGGSGIFGSLTSWNGLQEPESVPALE
                     GMLIVAYDAAGGFFGLDTGKFGRSGHIYYFAPDALEWESTELAYSGFLSWLAEGDLDLF
                     YQTFRWNGWQEDMEQLQHGEIFAYYPPLWTQEGGGETSSKSPIDITKAWQVVVDKE"
     gene            2570..3106
                     /locus_tag="C1T21_RS20180"
                     /old_locus_tag="C1T21_20185"
     CDS             2570..3106
                     /GO_process="GO:0042546 - cell wall biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311300.1"
                     /locus_tag="C1T21_RS20180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20185"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_103049500.1"
                     /transl_table=11
                     /translation="MWSIHFEQQFVKSLEATDEQIANFLKTWNIKLSEQEIHEIKQRQV
                     NPFPKSSPFYDQYKPLDPVSWHLPQGQFPDSYMDFLRYSNGGEFQNGERYFQFFNTKDL
                     REMNLAYELPEYMPGAVSFAMDGCGNHYMFDMREEKRNNEYPVLFAHSGSLGYDECEQV
                     AHSFIELCTEKWALY"
     gene            complement(3249..3833)
                     /locus_tag="C1T21_RS20185"
                     /old_locus_tag="C1T21_20190"
     CDS             complement(3249..3833)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821745.1"
                     /locus_tag="C1T21_RS20185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20190"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_061829653.1"
                     /transl_table=11
                     /translation="MTNIQNKKQVYIIHGYTASPADHWFPWLQDKLQEDGVSVGILEMP
                     NSQSPKLNEWIEHLLQNIKVLHKDTYFIGHSLGCVSILRYLQQVSIPEPLGGLVFVSGF
                     TDPVPSLPSLDEFTNGHLDYQQIMDSLKARSVIASKDDTIVPFALSKKLAEDIQADFHE
                     VDHGGHFLQSDGFTTLPMVHQVLIEMMNANK"
     gene            4185..5930
                     /locus_tag="C1T21_RS20190"
                     /old_locus_tag="C1T21_20195"
     CDS             4185..5930
                     /GO_component="GO:0098561 - methyl accepting chemotaxis
                     protein complex [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688156.1"
                     /locus_tag="C1T21_RS20190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20195"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_103049501.1"
                     /transl_table=11
                     /translation="MSNKQSDRTKKGKGFRDLKVTTTMISMIVISLVGLLIVSLVGVIG
                     MYQAKEGQGILYVDRFQHQTNILEVKSDFYNMRANYTKILDNKEYTDKQYKQVQKGKDS
                     VTTGLNEFSQRNLDAKEQKLYEELRGSIDTYYQDIEQIMAVKKNSGTYDTEERGRINKS
                     STAIVTMLTTISDYNNEQSANLYQNTQNEIKMRTIVLITVLALVLAILITISFAAIRNI
                     RFRMSTITKYCEEITQGNLTAALDPALLKGNNEIAVIARAIQQMTDSTSMVITGVINES
                     RQINQLSDQTNHNMTDLNERIRDVSATVEQLSAAMEETSAYTENMNHSAEEMQRAAEYI
                     SVKTQERAQSANDTSVKAETLKHAASESNKAAKEIYRKANEKMKEALERAKAVDQIRLL
                     SQSILEITAQTNLLALNASIEAARAGESGRGFAVVANEIRKLADGSKHAVDQIQSVTQE
                     VVQSVENLTTNAEELLHFLQAQVGKDYQLLEDTVGQYYMDAVEHTNTVNDLNATSKQVN
                     ATIQTMVRAIHEIATASEQSAISTQHIAENMVSSTEKSLEVAHQSDQVKESAARLNELV
                     EGFKI"
     gene            complement(6044..6613)
                     /locus_tag="C1T21_RS20195"
                     /old_locus_tag="C1T21_20200"
     CDS             complement(6044..6613)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428290.1"
                     /locus_tag="C1T21_RS20195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20200"
                     /product="DUF1697 domain-containing protein"
                     /protein_id="WP_103049502.1"
                     /transl_table=11
                     /translation="MIYIALLRGINVGGNNKIEMKKLKQTFENAGMGHVTTYINSGNII
                     FSSQTQSNQELSLILEQAILEDFSLPIRVIVRNMKEIQSIMEALPNEWSNDTQMKSDVL
                     FLWDEINDISVLDKLPLKPGIGHVIYTNGAVLFSVSKEQVTKSGLTKLVGSKLYQQMTV
                     RNVNTTRQIYKLMQMAEQEELRDTSS"
     gene            complement(6646..7296)
                     /locus_tag="C1T21_RS20200"
                     /old_locus_tag="C1T21_20205"
     CDS             complement(6646..7296)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428289.1"
                     /locus_tag="C1T21_RS20200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20205"
                     /product="hypothetical protein"
                     /protein_id="WP_103049503.1"
                     /transl_table=11
                     /translation="MKQLSEALACFVQQQNLYNDAYGLFQNHDIQPRTENLTDCWDRRI
                     PVSPELEYLYSHYEMIDAKAAGTHKLKNAAVEIGDAAVLFFAAPEHLYRQQLGYRWITS
                     GELVQESSSWPPHHVVIATFNDDPVIVDTSALGSPVYAAFEGGATQQVADSLANFFTAL
                     SILIEGACTFKGELKDEDTYETKAEYIEHVKPLLHPLLSENQTTYLMEYLSLC"
     misc_feature    7384..7397
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.61"
                     /tool="antismash"
     gene            7509..8501
                     /locus_tag="C1T21_RS20205"
                     /old_locus_tag="C1T21_20210"
     CDS             7509..8501
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311297.1"
                     /locus_tag="C1T21_RS20205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20210"
                     /product="hypothetical protein"
                     /protein_id="WP_103049504.1"
                     /transl_table=11
                     /translation="MSFSKIYDYKLRAYFNERISDLSHEYLFYSYPDQEQNLRILTLNI
                     NEQDYVSLVRWHDLFDRSLFTKMDHPILSVADAERLIRLLSLIFNVFDIHKDAAYSRKN
                     LCCVYYQYQVSHLAERGNEFTFAKDRLLFLHHLLFDLGLGDDIYDRLTIETNRIMYRME
                     DAQYYDLHILINILHEHINKSKMDMDTQAALEKIKFLQGQWVNFILGSHDVYDFPFDDF
                     NKPFVEATMFIQAYKSNKNRVLEVLIDCINEHQSPTEQFISHLILMNYSYFVLKSNPSE
                     ITYLKLFCKKKPGVFMKILTALLDIRFFVDKSSFTNAGINYYLSRIKGV"
     gene            8826..9779
                     /locus_tag="C1T21_RS20215"
                     /old_locus_tag="C1T21_20220"
     CDS             8826..9779
                     /EC_number="3.2.2.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372337.1"
                     /locus_tag="C1T21_RS20215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20220"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_103049691.1"
                     /transl_table=11
                     /translation="MALIKDRFLGCLVGLAVGDALGTTVEFSSPGTFEPVTDIVGGGVF
                     GLKPGQWTDDTSMALCLAESMVRKDGFDPADQMRRYTNWYHLGYMSSTGTCFDIGGATR
                     AALHRFEATGDPYSGSIDPMTAGNGSIMRLAPVAMAYANRPEEAVKYAEMSSRTTHGAA
                     ESVEACAVLASILVAGLRGADKESMLSAEVCYKWRQDEPAYSAAIEEIIRGSYRYKEPP
                     EIQGTGYVIRSLEAALWAFHHSTSFEEGALLAVNLGDDADTTGAVYGQIAGAYYGVSGI
                     PSRWREKLAMKEMIDELTEALWQKVEKDQTLQGEHL"
     misc_feature    complement(9977..9991)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.4"
                     /tool="antismash"
     gene            10001..12388
                     /locus_tag="C1T21_RS20220"
                     /old_locus_tag="C1T21_20225"
     CDS             10001..12388
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007431396.1"
                     /locus_tag="C1T21_RS20220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20225"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_103049506.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-43, bitscore:
                     144.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHHMNEKLQANTGYQLAERKAIQYFALLYDQVIDKSYVTTLTEDI
                     QKWKKNHIYHSSWLSFFSRRKRKPDTRDYNRYIQWLNYTGKLDDYLDRSVSYIYMRDLG
                     KALNSPDTHTRIQRVIADVKKHLIQSTSANGGDQPEFMNLAGVYRWAQREGIETAIIWV
                     INKLRSVSSHIPKEMDAEQAQRKLIKIIIGVILHVMEEMDDTVSPMERARRLDEAIRLG
                     YSYGLTYPFIDDLLDSQVLNVQEKEQYSRMIRAGLLSGSVPEMGDWTGNHMRLIQYIHS
                     ELSDAFEYIKEHQRPDTQQTFFEQAYVFFHSQDIDRVKDLTRATYTNEELYIPVILKSS
                     SSRLIVRSVISAPADEGFEQRTFFYGIYNQLADDFADMVDDMRDGAVTPYTYYLKYHHQ
                     RPDLINPFELYWAVISYLIHNVYDSDAMAREVILDRAMNGLKRYKERVGIEKYNETMEI
                     FASGNPEFNNLIQKMVQKADDVDFLDKLLRDQMITHLKNDAREKEDFFNTVKMVREQIN
                     NQLKITKPQGIPAMKEQLIEAANYSLEGDGKRIRPILTWVMGVNEYGLDASAIVPLLRS
                     LEYMHTASLIFDDLPSQDNASTRRGRQTLHQVHNSATAELTGLFLIQKAIGEQSSLDQF
                     NAETVLALIQYSAQKAEDMCMGQAMDLDSKGKALTLEQLNMVCFYKTGVAFEACLVMPA
                     MLAQVKEPEIAALKKFAYHMGIAFQIKDDLLDVEGDMLLLGKPVGQDSDNNNSNFVSIL
                     GLEGASKEMWEHYCLAMEALEEIPRNIAFLKHLIHYVVNRDR"
     gene            12616..13155
                     /locus_tag="C1T21_RS20225"
                     /old_locus_tag="C1T21_20230"
     CDS             12616..13155
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688148.1"
                     /locus_tag="C1T21_RS20225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20230"
                     /product="CueP family metal-binding protein"
                     /protein_id="WP_103049507.1"
                     /transl_table=11
                     /translation="MKKGILVASGLVVAALGTYLIAGNIQKEGAEKHETTDIKKLVHDI
                     SAGKATAQSASINSSQLIVTGDDTQTINYDLPDNEFFVSIAPYVEQTHPCATHSLTGCQ
                     GEIKNGAFNVTVHDSEGNVIMENAAMKSQSNGFIDLWLPRDKTYRISVNHEGKTAETEF
                     STYEKNDTCITTMQLS"
     gene            13440..15503
                     /locus_tag="C1T21_RS20230"
                     /old_locus_tag="C1T21_20235"
     CDS             13440..15503
                     /GO_process="GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372332.1"
                     /locus_tag="C1T21_RS20230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20235"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_103049508.1"
                     /transl_table=11
                     /translation="MSQNIKKSIFRSSSIANTLAMVLLVIIVVVFATLGTFMFASTQSI
                     LVKQQEAMLQTKTQAVVTQFDALFKEKGSLVKQMSTNNLFKQYLETTPSAEMVKTSPYA
                     AETVATLAAIVKAEPSFADAWIAGISGKGFFLQNDGVASKPDFDIHTRPYFKPAVEADG
                     LYYSEPYKDVNSGNVLMGIFYPIKDRSNQLIGFAAVDIAFKDIPAVMQSYSLGSTGYSI
                     LASKTGDILYHPDQNKVLKEKINESTGDLGEIGKKMIAGESGVQLINDNGERRYIGYAT
                     SKDTGWSVGLTISEEEVLTELKTFTWLTIGGFAAATILLVVICYITLRYLLRSIPKLLA
                     KIKLIENGDLTVQFDTQSNNEIGQISQGIYNMVQKIQGMLQMVGGSAQVLNQSSHDLQS
                     ISSRTAITMNDTATAINEIANATNYQSIETDNILQKTGALSGQIDEIANDAKAIETMVQ
                     ISAEQSGQGLAVVDQLSRWAEENHNSTQAMSSIIQEIDLSRHEISSIVDTVNQIATQTN
                     LLALNASIEAARAGEQGKGFAVVAGEVRKLAEQTALATQEIYKKVRVIEEKTSVSVEHT
                     VHGLKIAEENARSVEDTKQVFFSINKDLEDLKLRMIQISTNTSKVHKHKDEILQALEII
                     SSTTEENSASTEEVSASTQEQLESFEQVAELSKQLNQLSNKLQDELKQFKVE"
     misc_feature    15522..15540
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 23.92"
                     /tool="antismash"
     misc_feature    complement(15523..15541)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.69"
                     /tool="antismash"
     gene            15661..16041
                     /locus_tag="C1T21_RS20235"
                     /old_locus_tag="C1T21_20240"
     CDS             15661..16041
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821733.1"
                     /locus_tag="C1T21_RS20235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20240"
                     /product="immunity 22 family protein"
                     /protein_id="WP_103049509.1"
                     /transl_table=11
                     /translation="MNCFEKNMVSVWYGHFASEDELFEYVEIKYPEDENENIFSGFLND
                     HKIDDFDEDFAEGVFLVDGSDDGIKDVSYVDSFLSPLLHDLSKVDGKYNSLIFIYDCNT
                     SGLSEKNGEEPRFLAAYPYSKD"
     gene            16236..16382
                     /locus_tag="C1T21_RS28160"
     CDS             16236..16382
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS28160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_230585172.1"
                     /transl_table=11
                     /translation="MKITYFIGRSKKDRQALLSKAAFAVVEQYIGVESQKTGCFQGRGK
                     AAT"
     gene            16379..16633
                     /locus_tag="C1T21_RS27445"
                     /old_locus_tag="C1T21_20245"
     CDS             16379..16633
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012798.5"
                     /locus_tag="C1T21_RS27445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20245"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_103049510.1"
                     /transl_table=11
                     /translation="MTERSAQKVFDKTLAEAGIHKQVSIHSLRHSFATLLLENGIDLRY
                     IQELLGHQSVRTTERYTHVSRRDIGRIQSPLDRMSGQED"
     gene            16802..17482
                     /locus_tag="C1T21_RS20245"
                     /old_locus_tag="C1T21_20250"
     CDS             16802..17482
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS20245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C1T21_20250"
                     /product="hypothetical protein"
                     /protein_id="WP_025720963.1"
                     /transl_table=11
                     /translation="MNNKFVIALVCVITFLAIFPFFINVSFMGWRTSITFGSTESWIGF
                     FASYFGAIFGGVIGGLFTYLGVRQTINTQTKQKYIDEFPEKIKLLTDVLFKLKGQRDSF
                     NNNEYFIKGLAQYERPSEYFDLMSSTISSAAESGNKIDGALYEKMKEIRERKDNCILKS
                     ANHPLISLVIADDEFGTNARVSLESINFRRQVQAEITQIINDLISIFEDQLIKMEQKFK
                     QYIK"
     misc_feature    complement(17689..17704)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.54"
                     /tool="antismash"
     gene            18222..19364
                     /locus_tag="C1T21_RS20250"
                     /old_locus_tag="C1T21_20255"
     CDS             18222..19364
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001994974.1"
                     /locus_tag="C1T21_RS20250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20255"
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_103049511.1"
                     /transl_table=11
                     /translation="MGRKISDHVQRMLYAESMGRCMNPDCKVELFRDNGDIIEKAHLTP
                     FCDSEDNSFENLVVLCPNCHTDFDKNSAFTKVHVTMWKQNRKEEFDRFFGEKFSTFDEL
                     RSRVAPLLKENKVIFENYYIGDKKELWNVFEGKILANNNMLKKLLEQNRNLIQRHSDES
                     YSNLAIIDTFLVHISEFESTRPTVEKHRQVLFPEEINSLFGIEPVDQSLLPSVESLEIL
                     INKLQRQGEFVGIVLGTDNPYIELLEDGNVVKLYLNDTPRLRQFYFDYGCFRGAKVRLD
                     SLNFAYKFIKTRGVMFEFNDYTNLREVIVKGKKMIFIYNYCLSKVDLMKLTPSENSILV
                     NLHNWNGKGCISSEAYALADEMAVTLLTMDKFYVYVNRLK"
     misc_feature    19416..19431
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     misc_feature    complement(19886..19901)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.54"
                     /tool="antismash"
     gene            20319..20786
                     /locus_tag="C1T21_RS20260"
                     /old_locus_tag="C1T21_20265"
     CDS             20319..20786
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688144.1"
                     /locus_tag="C1T21_RS20260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20265"
                     /product="DUF2691 family protein"
                     /protein_id="WP_028542564.1"
                     /transl_table=11
                     /translation="MNRGISFEIPNSYGSHLGEILKPIDITTFSWFIGGEESYFIVDDT
                     LGGNLFPDMVTGMDGEDLKKIIDYNKYYLIFANLKAYPKGANIIDVMSYEEYIASECQI
                     ILLVIDSVYITVYCKDLEKLEDLYDHIKRKGYKSLEYITDENDTRTRLSVW"
     gene            21147..21893
                     /locus_tag="C1T21_RS20265"
                     /old_locus_tag="C1T21_20270"
     CDS             21147..21893
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006211639.1"
                     /locus_tag="C1T21_RS20265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_20270"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_025721319.1"
                     /transl_table=11
                     /translation="MNKHSVYETNSFYWDTKGNDFLGAIVLPFYGAFVSEEKCQLFGDV
                     SGKKMLEIGCGNGQSLQYQGDRKASELWGMDISEKQIEKAKQHLTACGLSAKLICSPME
                     EECDIPVDYFDFVYSIYTIGWTTDLEGTFCRIASYLKKDCVFIFSWSHPIHKCVVEENN
                     RFAFNKCYFDESWYSVSPDFCQGALTLSDRKLSTYINALAKAGFVIEQMIEETENEIIQ
                     LHDENNDFVKRAKMFPVTFVIKARKL"
ORIGIN
        1 ttcaagctgg aacagtgtat gaataaacga gctaaatgcc acgttatgtt atagtctctg
       61 gaaaaattga gcctgagtcc attgagatgt actctgaaca ggaggagcag atgaatcgtt
      121 ggctaacgaa cgcgttacga ccgtacttcg ggctggagac gctggaagag cattgggacg
      181 tggtagaaat taaagaagga tactttattt gtatggatgg ggatgtcatt cgcaagcgaa
      241 tttcttccac tgaggatact tatggagaaa ccgatgtaga gattcttacg cgtgaccggg
      301 catttgtttt gcctaaaacg gctcgtggca aagagaaaaa gctgaattac acaagtgttt
      361 cgagcatcaa ggcagaaggc ataacctttt caacaggcat tcgaagggat cgtcctctta
      421 gttatgttac tgctgtgaat agcaaaacgg gtgtgaaact ccctattacg ggatgtgagc
      481 atttacatag taaagaagag atcatcgatt ggcttcagca atatccgtca cttgtgccca
      541 aggattacga tcgcagattg caccgactga agcttatgaa aaaccagcgt tataaaacgg
      601 tcccgggaga catctttcgc gtggaaatag accttttcac agatggatat gtactggtca
      661 ttggagatct gcgccaaatg caaaagaatc agttgtttgc agaggagagc atttggaaca
      721 gtgtcatgac catgccttta ttcgtgcgtc cgtatttgtt tacgagtcgt gaccgttcaa
      781 cagctttgga atctatcaca gccgccccat tatccgaaac gacctggatt gttatggatg
      841 attcctttat gcggggtgcc tatgagcggg tagggcataa gctattagtg gaagaggata
      901 ttgtgttccc catcggctat ggctgtagta cggatagtag aaaagaaaga acatatagtc
      961 tgtcctgggg aacgggcacg gtttccaaac cggaagggga gacagtgttc aagtcttcac
     1021 gaaaattttt aaataacggt gtgtattcaa gtgtcgttgc cgactgtttt ggctcctggg
     1081 aagagcggga gtggtacaaa atgctggata atccgttata tcaggatgag cgtcgaaaag
     1141 cactggccga attcggattc ctggaagaca tttcgtatga tgagttcaac cgtcaaacgg
     1201 gaggactgac acgttcggaa tatctcgcat atttgataag aatctatggc gggaaaaaat
     1261 gatgaaaacg gatttgattt tttaatagga ggggccaatg aaatatctta aagattgtcc
     1321 ggaaccaggc atgggaacct ggtattttga aatagattcg gatggaatag cctatcgaca
     1381 aattgtcatc caggatgatg gcacgtatat cgcctctaat cgcaagcacg agcagtatca
     1441 tttcttatta gctgagaaag cgattgatga tacagagccc tattatacgc aaattacaaa
     1501 aaaaagagtt tgaagaaatc tggtccaatt atcttcacac cttcaacaag gaatggcatc
     1561 aaatcaaaaa tgcactgccc gttgggacta aggtaaaggg ttatattgaa gcatttttcc
     1621 cacacggtac gcttattcat attttccagc atcatgcggt cggattgtca gacactcgta
     1681 catatgagga aaagacacca tccgagtgga tgtatccgaa gcatgaggtc acggccattg
     1741 taaaaggata cgacgaagtg aaccagtggg tgattttaga tcaaacgcag gttttcaaaa
     1801 atcagttcgc aggttgaaag ggaattttag gatatgcggg aaggggaatg aacatgcata
     1861 ctttaacggt tgatgaactg gtggataagg ataaccatgc atgggaagag gtcagaaata
     1921 ttctgaaaga aggccggaat tcacatcaca ttgtatcggc cgaatcggaa tccgctacgg
     1981 gggacacgct gtaccgtttg caggtgagta cgaagtcgta tttgggaaca gttgcctatg
     2041 agacaggagg aattgtgttt gattacggtt ggatcacctt gctgggtgcg ggtggctctg
     2101 gaatttttgg tagcttgacc tcatggaacg ggcttcagga gccagaaagt gttcctgcac
     2161 ttgaggggat gctgattgtg gcttatgatg cagcaggtgg attttttgga ttggatacag
     2221 ggaaattcgg acgtagcggt catatctact attttgcacc agatgcattg gaatgggaat
     2281 ccacagagct ggcctattcc ggtttcttga gctggctggc tgagggagat ttggacttgt
     2341 tctaccagac attccgctgg aacggttggc aggaggatat ggagcaactt cagcacggag
     2401 agatatttgc ttattatccg ccgctatgga cccaggaagg tggaggggag accagcagca
     2461 agtcgcctat agatattaca aaagcatggc aggtggtagt ggataaggaa tagcttgctc
     2521 ggtagaaata acaactctta gaggcatcga ggtatggagg ttggccgata tgtggagtat
     2581 tcactttgaa cagcagtttg taaaaagtct ggaagcaacg gatgaacaaa tcgcaaattt
     2641 tttgaaaaca tggaacataa agctatcgga acaagagatt cacgaaatca agcaaagaca
     2701 agtgaaccct tttccaaagt cgtctccatt ctatgatcaa tataaacctt tagatcctgt
     2761 gagctggcat ctgccccaag ggcaatttcc tgacagctat atggattttt tgagatactc
     2821 taacggcggg gagtttcaaa atggagaacg ttattttcag tttttcaata ccaaagattt
     2881 gagagaaatg aaccttgcct acgagttacc ggaatatatg ccgggtgctg tgtcgtttgc
     2941 gatggatggg tgcggaaacc actatatgtt tgatatgaga gaggaaaaaa gaaacaatga
     3001 gtatcccgtt ctttttgctc attctggtag tttgggatat gacgaatgtg aacaggttgc
     3061 ccattcattt atagagctgt gtacggaaaa atgggcattg tattgatgta ttgactataa
     3121 gtacatctgt ggagcgactc cttgttaaga cgtacgtatt ccagaagtga ttacataacc
     3181 cgcaataatg aacccttcgc cggttccatt ttgcgggtta tgtaagtttt caaactaagc
     3241 ctgtcatgct acttatttgc attcatcatt tcaattaaca cttgatgtac catcggtaag
     3301 gtggtaaaac cgtcactttg taaaaagtgt cctccatggt ctacttcatg gaaatcggct
     3361 tggatgtctt cagctagttt cttactgagt gcaaagggca caattgtgtc atcctttgaa
     3421 gcgataactg aacgcgcttt tagcgaatcc atgatttgct gataatccaa atggccattg
     3481 gtaaattcat ctaatgacgg tagactcggc actggatcag taaaaccgga aacgaaaacg
     3541 agaccaccaa gtggttctgg gatacttact tgctgtaggt atcttaatat ggatacacat
     3601 cccaagctat gaccaataaa ataggtgtct ttatgtagaa ctttaatatt ttgtaataga
     3661 tgctcgatcc actcattaag tttgggggat tgcgagttgg gcatctccag tatacctacc
     3721 gatactccat cttcctgtaa tttgtcttgt aaccaaggga accaatgatc ggctggcgaa
     3781 gctgtgtatc cgtggattat atatacttgt tttttatttt gtatgtttgt cacaatactt
     3841 tctctcccat cattcagcgt ttgttgttta tatgtgcccc acttcgtgta aggactcctc
     3901 ttctagttta gcaaattctt taagcccatg aatatctaaa attttgagtt acatagcaag
     3961 tccaaatatg aagttgccta ctataatatt cttatttttg cagtaccgtt agtttactta
     4021 taaatttaag cgctttctac cgatatatag atatatatat catcacgttc tgtgatctgc
     4081 ttcattttgt tgtttggagg gcaatgtcaa ggagaccgac tggaaactcg tgaaagttga
     4141 gagcagcgtg aactattatc catagacgat ctggaggggt ttggatgagt aacaagcaat
     4201 cagacaggac taaaaaagga aaaggtttta gagatttaaa ggttacgaca acgatgatct
     4261 ccatgattgt aatcagctta gtaggtttac tcattgtatc gttggtaggg gttatcggta
     4321 tgtatcaagc taaagagggt caaggtattt tgtatgtgga tcgctttcaa caccaaacga
     4381 atattcttga agtcaaaagt gatttctata atatgcgggc taattataca aaaatactcg
     4441 acaataagga gtacacagat aaacagtata agcaggtgca gaaaggaaaa gatagcgtta
     4501 caaccggact aaatgaattc tcacaaagga atttggatgc taaggaacag aaattgtacg
     4561 aggaactacg ggggagtata gacacatatt atcaggatat tgagcaaatc atggcagtca
     4621 aaaaaaatag cggaacgtat gacacggaag agagaggccg gattaataaa tccagtacgg
     4681 caattgttac gatgctgact acgatttcag attataacaa tgagcaatcc gccaacttat
     4741 atcaaaatac gcaaaatgag attaaaatgc gtacaattgt tttgatcacg gttctggccc
     4801 ttgtgctggc tattcttatc accatctcct ttgcggccat tcgaaatatc cgtttccgga
     4861 tgagtacaat tacgaaatac tgtgaggaga ttacccaagg aaatttaacg gcagcacttg
     4921 atcctgcctt gctcaaagga aataatgaga tcgctgtcat tgctcgtgcc attcaacaaa
     4981 tgacagattc aacctcaatg gtcataacgg gggttatcaa tgagtcacgc caaattaacc
     5041 aactgagtga ccagacgaat cataatatga cagatctcaa tgagcggatt agagatgtat
     5101 ctgccacggt cgaacagctg tcagcagcta tggaagagac ttcggcatac accgaaaaca
     5161 tgaatcattc tgcggaagaa atgcagcggg cagcggagta catctcggtc aaaactcaag
     5221 aaagagctca gtctgccaat gatacaagtg taaaagccga aacattgaag catgcggcta
     5281 gtgaatccaa taaagcggcc aaggaaattt accggaaggc caatgaaaag atgaaggaag
     5341 cgctagaacg agccaaggcc gtagaccaaa ttcgtttact ttctcagtct atcttagaaa
     5401 ttacggcaca aaccaatttg ctggctctaa atgcatccat tgaagcggct cgtgcgggtg
     5461 agtcaggtcg agggtttgcg gttgtggcta acgagattcg caagttggca gacggctcca
     5521 aacacgcggt agaccaaatt cagagtgtta ctcaagaagt tgtgcaatct gtagagaatt
     5581 taactactaa tgccgaagaa ttactgcact tcctgcaagc acaggtaggc aaggattatc
     5641 agctgcttga ggatacagta ggacaatatt acatggatgc agttgaacac acaaacacgg
     5701 tcaatgattt gaacgccacc tctaagcagg tgaatgcaac catccaaacc atggtgagag
     5761 cgattcatga gattgcaaca gccagcgaac agtccgctat atccactcag cacattgcag
     5821 agaatatggt ttcatcgacg gagaaatctc ttgaagtggc acaccagtct gatcaggtga
     5881 aggaaagcgc ggcccgactg aatgaactgg tcgaaggctt taaaatttaa cgaggcccat
     5941 cgtaaagact agggaaaaca ttacatcaaa gaaaaacagt tggggagccg taaaaaggct
     6001 ccctttttga gtttaccctt ccaacgttgc ttttggacta ttgtcaggaa ctcgtatccc
     6061 gtagctcttc ctgttcagcc atttgcatga gcttatagat ctgtcgtgtt gtgttcacat
     6121 tccgcaccgt catttgctga tacagcttgg agccgactaa tttcgttaac ccgctttttg
     6181 tgacttgttc tttgctgaca gaaaacagaa cggccccgtt cgtatatatt acatgcccaa
     6241 ttcccggttt caaaggtagc ttgtccagaa cggaaatatc gttaatttca tcccacagga
     6301 acaatacatc acttttcatc tgtgtatcat tagaccattc attcggcagt gcctccataa
     6361 tgctctgaat ctctttcatg tttcggacga tgacgcggat gggtaagcta aaatcctcca
     6421 gaatcgcctg ttccaatatg agtgaaagct cctggttaga ctgggtctga ctagaaaaaa
     6481 taatgtttcc agaattaatg taagtcgtca catgccccat acctgcattt tcaaacgttt
     6541 gcttgagctt cttcatctcg atcttgttgt tgccgccaac gttgatgccc cgcagtaatg
     6601 cgatatagat catataagct ccacctctct tcaaaaaaag gatttctaac aaagggatag
     6661 gtattccatt aaatacgtgg tttgattttc gctcaacagc ggatgcagca atggttttac
     6721 gtgctcgata tattctgctt tggtttcgta tgtgtcctca tctttcaatt ctcccttaaa
     6781 ggtacaggca ccttcgatca ggatggaaag agccgtaaag aagttagcta aagagtcggc
     6841 aacctgctgc gttgccccac cttcaaaagc agcatataca ggggaaccga gtgcgctagt
     6901 atcgacaatg actggatcgt cattaaaagt ggcaattacg acatgatggg gcggccacga
     6961 agaagattct tggacaagct caccagatgt aatccagcga tagcccagct gttggcgata
     7021 cagatgttct ggtgcggcaa aaaagagaac cgcggcatcc ccgatttcaa ctgctgcatt
     7081 ttttaatttg tgtgttcccg ctgccttagc atcgatcatt tcataatggc tatacaggta
     7141 ctcaagctca ggggatacgg gaatccgtct gtcccagcaa tctgttaggt tttccgtccg
     7201 gggctggatg tcgtggtttt ggaacagccc gtaggcatca ttatataagt tttgttgttg
     7261 tacaaaacag gccagagctt cgcttaattg tttcataggt ttgcattcct ttctaatttt
     7321 aggctatgac cttcgacaat aacgtttcat ttctagccta aagatatcat aatatagata
     7381 tggagaacat atgtttctgt aattgtgccg ccttgccagt ctatccagat taattttaca
     7441 atataggagt tcgaacatgt tttgtactta gtttaatatg ctcaggctta cttgtaagga
     7501 ggataagcat gtcattttct aaaatatacg attacaaatt aagagcttat tttaatgagc
     7561 gtatttctga tttaagtcat gaatatctat tttattctta tcccgatcaa gagcaaaatt
     7621 taagaatatt aaccctgaat ataaacgagc aggattatgt ttctctagtg cgatggcatg
     7681 atctgtttga caggtcgctg tttacaaaaa tggatcatcc cattctaagc gtagcggatg
     7741 ctgaacgcct gattcgattg ctttcgctca tttttaatgt ttttgatata cacaaagatg
     7801 ctgcttatag cagaaaaaac ttatgttgtg tttattatca atatcaggtt tcacatctag
     7861 cagagagagg gaatgaattc acgtttgcta aggacagact acttttcctt caccatctct
     7921 tatttgatct gggtttaggt gacgacattt atgatcgcct gacgattgaa actaatagga
     7981 ttatgtacag aatggaagac gcacaatatt atgatctgca cattcttatt aacattttgc
     8041 atgagcatat taacaaaagt aagatggata tggatacaca agcagcgctg gaaaaaataa
     8101 aatttttaca aggccaatgg gttaacttca ttctgggtag tcatgatgta tatgattttc
     8161 cattcgatga tttcaacaag ccgtttgtag aagcaacgat gtttatacaa gcctacaaat
     8221 ctaataaaaa tagggtgtta gaggtgctga tagactgtat caatgagcat caatctccaa
     8281 cagagcagtt catctcccat ttgatcttga tgaactattc ctattttgtt ctcaaaagta
     8341 atcctagcga aattacatat cttaaattat tttgcaagaa aaaaccggga gtttttatga
     8401 aaatattaac tgcattgctt gatatcagat tttttgttga taaatccagc ttcacaaatg
     8461 cgggtataaa ttattattta tccagaataa aaggggttta atgatgccat tccatcacgt
     8521 ttctttacct gatttaccac cgtctatcgg acgccttgca gccattcatt cactacaggg
     8581 cgactctcag gaaagcataa ccctgctggc actaaacata caagcagaac tgtggagact
     8641 agaacttcgc tctggcagca ctcgtttacc atcacgaggc ggggattttc attgaattaa
     8701 aaccgaatag ccgttgtaca gccttgatct acgaataaaa ggcgttaccg catttttgct
     8761 tccttcctgg cgagatggga aaatatgcgt tagttattac atttgaaaag gggcgtaaaa
     8821 ccaaaatggc acttatcaag gatcgttttt tgggatgcct ggttgggctg gccgtgggcg
     8881 atgctttggg aaccactgtg gaattcagca gtccaggtac atttgaacct gtaacggata
     8941 tcgtgggcgg cggtgtcttt gggttaaagc cgggccagtg gacagacgat acgtcgatgg
     9001 cgctctgctt ggccgagagt atggtacgta aagatggctt tgatccggca gatcaaatgc
     9061 gccgatacac caattggtac cacttgggat atatgagtag tacgggaacg tgctttgata
     9121 tcggtggtgc aacgagagca gcactgcatc gcttcgaagc taccggagat ccgtacagtg
     9181 ggtccattga ccccatgact gccggcaatg gctctattat gaggcttgca cctgtggcta
     9241 tggcctatgc gaaccgtccg gaagaggcgg tgaagtacgc tgagatgagc tcgcgaacca
     9301 cccatggagc agccgaaagt gtggaggcct gtgctgtgct tgcttcaatc cttgtggcag
     9361 gtctgcgagg agcggacaaa gaatccatgt tatcggcgga ggtctgttat aagtggcggc
     9421 aggacgagcc tgcttattcg gcagccattg aagaaataat tcggggatct taccggtata
     9481 aagagccgcc cgaaatacaa ggaaccgggt atgtcattcg ttcccttgag gctgcgttgt
     9541 gggcatttca ccattcgact tcatttgaag agggggcact gctggcagtg aatctgggtg
     9601 atgatgccga tacgaccgga gcggtatatg ggcaaattgc aggagcttat tacggagtaa
     9661 gcggtatccc aagtcgttgg cgcgagaagc tggcgatgaa ggagatgata gatgaactga
     9721 ctgaggcttt atggcagaag gtcgagaagg accaaacgct ccaaggggaa catctataaa
     9781 gatcaagctg ggctgctttt cttatggagc agagcccagc tttttttgtt cactatattt
     9841 catgacgatt cacctcttgg gattacttct tatatcgcct cgaccccatt aaatttcgta
     9901 accttacaga tttttttccg tataaagata aaaacatgat ccgaattcgt accctcaggg
     9961 agaaatgcaa ccatgtttaa caaaatgaga agttgaggta atgcatcata tgaatgaaaa
    10021 attacaagcc aatacaggat atcagctggc tgagcggaag gcgattcagt attttgcatt
    10081 actgtatgat caggtcatag acaaatctta tgtgactacc ctgacagaag acattcaaaa
    10141 gtggaaaaaa aatcatattt atcattcctc atggttatcc tttttttcac ggagaaagag
    10201 aaaacctgat actcgggact ataatagata cattcaatgg ctgaattata caggcaaatt
    10261 ggatgattat ctggaccgaa gtgtctccta tatttatatg agggacctag gcaaagctct
    10321 gaattctcct gacacacata cccggattca gcgtgtcatt gcagacgtaa aaaaacactt
    10381 gatccaatcc accagtgcaa acgggggaga ccaaccggaa tttatgaatt tggccggggt
    10441 gtatcggtgg gcccagaggg aaggtataga aaccgcgata atttgggtga tcaacaaact
    10501 taggtccgta tcctcccata ttcccaaaga gatggatgcc gagcaagccc agcgcaaact
    10561 gattaagatc attatcgggg ttattttgca tgtgatggaa gaaatggacg atacagtgtc
    10621 acctatggaa cgtgctcgca gacttgatga agccatcagg cttgggtact cctatggtct
    10681 aacctatcct ttcattgatg atcttctcga ctcccaggtt ctgaacgttc aagagaaaga
    10741 acaatattcc cgtatgatac gtgccgggct tctcagtgga tctgtgcctg agatgggcga
    10801 ttggactgga aatcatatga ggttgattca atacatacat tcggagctct cggatgcatt
    10861 tgagtatatt aaggaacatc agcggccaga cacacagcaa acatttttcg agcaggctta
    10921 tgtctttttt cattctcaag atattgaccg tgttaaggat ctgacgcgag ctacttatac
    10981 taatgaagag ctttatatac ccgttatttt gaagtcttct tcgtcccgat tgattgtccg
    11041 ttctgtgatt agtgctcctg cggatgaggg gtttgagcaa cgaacattct tttatggcat
    11101 ctataaccag cttgctgatg attttgcgga tatggttgac gatatgagag acggtgcggt
    11161 aacaccctat acctactatt taaaatatca tcatcagaga ccggatttga tcaatccctt
    11221 tgaattatac tgggcggtta tttcctattt gatccataac gtatatgact ccgatgccat
    11281 ggctcgtgag gtgatactgg atcgtgcaat gaatggactc aaacgttata aagaacgtgt
    11341 aggtattgaa aagtataatg aaacgatgga gatctttgca tccggaaatc cggaatttaa
    11401 taatctcatt cagaagatgg tacaaaaagc ggatgatgta gatttcttag ataagctgct
    11461 tcgggaccag atgattaccc atctgaaaaa cgatgcgagg gaaaaagaag actttttcaa
    11521 tacggtcaaa atggtccgtg agcagattaa caaccaattg aaaattacca agcctcaagg
    11581 gattccggcc atgaaagaac agcttattga ggctgcaaat tatagtcttg aaggggacgg
    11641 gaagcggata cggcctatat tgacttgggt catgggcgtg aacgaatatg gattagatgc
    11701 atcggcaatt gtgcctcttc tgagatcatt ggaatatatg catacagcct ccctgatttt
    11761 tgatgatctt ccttcccagg ataatgcgtc tacccgtaga gggcgtcaga ccttgcatca
    11821 ggtgcacaat agcgctaccg cagaattaac cggtctgttc ctgatccaga aggcgattgg
    11881 ggaacaatcg tcacttgacc agttcaatgc tgaaacggtg cttgctttga tacaatactc
    11941 ggcccagaaa gcagaagata tgtgtatggg gcaggcgatg gatctggatt ccaaaggaaa
    12001 ggcactgacc ttggagcagc tgaatatggt gtgcttttac aaaaccggag tggcgtttga
    12061 ggcttgtctg gttatgccag ccatgcttgc acaggtcaag gaaccggaaa ttgctgcttt
    12121 gaagaaattc gcctatcata tggggattgc ttttcagatt aaagatgatt tgcttgatgt
    12181 ggaaggagat atgctcttac tcggaaaacc tgttggccaa gattctgata acaacaattc
    12241 gaatttcgtg tccatccttg gtctagaagg tgccagtaaa gagatgtggg aacactattg
    12301 tctcgctatg gaagcattag aagagatccc acgtaatatt gcttttctga agcacttaat
    12361 acattatgtc gtgaaccggg accgttaaaa aacgagtgtg ccccattgct ccacaagagt
    12421 aatgggtgtt tttacgttga gaccgaagag ctgctcatgt tccttcgttc atcggtaatc
    12481 ctctaatgtg atataaatat gtctgagcac gcaacacaga tatgtgaata tctagtgact
    12541 tcagcacccc attttgccca ttatggtgca ttctccctta taataataca aaacagatga
    12601 ggagatgaac tccagatgaa aaaaggaatc ttagtcgctt cagggttggt tgttgccgca
    12661 ttggggacgt acctaattgc aggaaatatt cagaaagaag gggcggaaaa acatgagacg
    12721 acagatatca agaaattggt gcatgatatc agtgcaggca aggcaacagc ccagtctgct
    12781 tccattaatt ccagtcagtt gattgtgaca ggggacgata ctcagaccat taattatgat
    12841 ttgcctgaca acgagttttt tgtttcgatt gcaccatatg tggaacagac ccacccatgt
    12901 gcaactcata gtctaacggg ctgccaaggc gaaataaaaa acggtgcgtt caatgtgacc
    12961 gttcacgact ccgaagggaa tgtcatcatg gagaatgccg ccatgaaatc acaatccaat
    13021 ggttttattg atctatggct accgagggat aaaacatacc gcattagcgt gaatcatgaa
    13081 ggtaaaacgg ctgaaactga attctctaca tatgagaaaa acgatacgtg tatcacaacg
    13141 atgcagttga gttaacgacg gaggatgagg gttgagctta cggatcgctg aaatgctcta
    13201 aatccgcaaa accctgcgtt ctcatatata gcttttagta aagagcctac gtctgacgga
    13261 ggctctttgt gctgccctaa tcttttgctg gagttacgga acaggtcggg agggaatcta
    13321 tgaggaatca gatagcaaaa ctttaaattg tatatactaa aaacctatta aaacagctgc
    13381 aaacttccga catattatct aagagctttt cgctcaatat tcctcgggga gatggcagca
    13441 tgtcacaaaa tattaagaag agcatattca gatcatccag catcgccaac acattggcca
    13501 tggtcttgtt agtcattatc gttgtcgtct ttgcaacctt ggggacgttc atgtttgcaa
    13561 gcacgcaaag catacttgtc aagcagcaag aggccatgct ccagaccaag acgcaggccg
    13621 ttgtcactca attcgatgcg ttgtttaaag aaaagggatc acttgtcaaa caaatgtcaa
    13681 cgaataatct ttttaagcaa tatttagaaa ccaccccatc ggcagaaatg gtgaaaactt
    13741 ctccttatgc tgcggaaaca gtagcgactc tggcagccat tgtaaaggca gagccatctt
    13801 ttgccgacgc ctggattgca ggaatatctg gtaaaggctt ctttcttcag aatgatggtg
    13861 ttgcttctaa accggatttc gatatccata cacgcccata cttcaagcca gccgttgaag
    13921 cagacggttt atactactca gaaccctata aggacgtcaa ttcgggtaat gtgctgatgg
    13981 gcattttcta tccgattaaa gatagaagta atcaattaat cggatttgct gctgtcgata
    14041 ttgctttcaa agacatccct gccgttatgc aaagctattc gcttggaagc acaggttatt
    14101 cgattcttgc gtccaaaaca ggagatattt tgtatcaccc cgatcaaaat aaagtgctga
    14161 aagaaaagat taacgaaagc acaggtgatc ttggggagat tggaaagaaa atgattgctg
    14221 gtgagtccgg agtacagcta attaatgata atggggaacg tcgttatatt gggtatgcaa
    14281 ccagtaaaga tacggggtgg tctgtaggct taactatttc tgaagaagag gtgctcacag
    14341 aattaaaaac ctttacctgg cttaccattg gcggttttgc ggcagccacc atcctgctcg
    14401 ttgtgatttg ttatataacg ctccgttatc tgttgagatc aatcccgaaa ttgcttgcaa
    14461 aaatcaagct gattgaaaat ggagatttga ccgttcagtt tgatacgcaa tccaacaacg
    14521 aaatcgggca aatttctcaa ggaatttaca atatggttca aaaaattcaa ggcatgctcc
    14581 aaatggtggg tggctcagct caagtcttga atcagtcttc tcatgatttg caatccattt
    14641 cttccagaac cgcgattacg atgaacgata cggcgacagc aattaatgaa attgccaatg
    14701 caacgaacta ccaatccatc gaaacggata acattttaca aaaaactggt gcattatccg
    14761 gccaaattga cgaaattgcc aatgatgcca aagccatcga aacgatggta caaatctctg
    14821 ctgaacaaag cggacagggg cttgctgtag tagatcagtt atccagatgg gcggaagaaa
    14881 atcacaattc cacacaagcg atgtcgtcta ttattcagga gattgatctg agccgtcatg
    14941 agatttccag catcgtcgat acggtcaacc aaattgcaac gcagaccaac ctgctggcgc
    15001 tcaatgcttc tattgaagct gcacgtgcag gagaacaggg taaagggttt gctgttgttg
    15061 ccggggaggt tcgcaagctg gctgagcaga ctgcactggc gacacaggaa atctacaaga
    15121 aggtacgtgt gattgaagaa aaaaccagcg tatcagttga gcatacggtt cacggtctga
    15181 aaattgcgga agaaaatgcg agatcggtgg aggacacgaa gcaagtattt tttagcatta
    15241 acaaggattt ggaagatttg aaattgcgaa tgatccagat cagcaccaac acctccaaag
    15301 tccacaagca caaagatgag attttgcagg cactggagat catctcttcc accaccgagg
    15361 aaaattcagc ttcaaccgaa gaggttagcg ccagcacgca ggaacaattg gagagctttg
    15421 aacaggttgc tgaactatcc aaacaattaa accaattgtc caataagctt caagacgaat
    15481 taaaacagtt caaggttgag taacaagtct actaggcatg atattggcta aatatacagc
    15541 aaagcccgcg ttcagcgggc tttttagctt caacagctgt tgtggggtag agggcatggt
    15601 agctggtgcg ggatacagat agaccatacg tataaactga aatattagcg gggtgaagat
    15661 atgaattgct ttgaaaaaaa tatggtgtcc gtctggtacg gtcactttgc ctctgaagat
    15721 gagttgtttg aatatgttga gatcaaatac ccggaagatg agaatgagaa tatttttagc
    15781 ggttttttaa atgatcataa aatagatgat tttgacgaag attttgctga aggagtcttt
    15841 ctggttgatg ggtcagatga tggtataaaa gatgtttcct atgttgattc ttttttatct
    15901 ccactattac atgatttgag taaagtagat ggtaaatata attcgttgat ctttatatat
    15961 gattgtaata caagcggttt atctgaaaaa aatggcgagg aaccacgctt tttagccgca
    16021 tatccttatt caaaagatta acggttacac tattcttttg tcttcggagt ctcattccaa
    16081 gtaattatga taatgaaaat tgaacttaaa ggatcaataa tttgatccga aagaatcagg
    16141 gccttaaggt gaatttacat cttaagtccc tttttttgtg tgaaaataga tttccaattt
    16201 tttgaacggc tgatatacta aggagacaag cgagcatgaa gattacctac tttatcggaa
    16261 gaagcaagaa ggatcgtcaa gcgttgctct caaaagcggc ttttgcggtg gtcgagcagt
    16321 acataggggt ggagagccag aagactggct gtttccaggg cagagggaag gccgccactt
    16381 gacggaacgt tcagcgcaga aagtatttga taagacactg gctgaagcgg gcattcacaa
    16441 acaggtaagt attcattcgc taaggcattc ttttgcgacc cttttgctgg agaatgggat
    16501 tgatcttcgc tatattcagg aactgctagg gcatcagagc gtgcgaacga cggagcggta
    16561 tacacatgtg agcaggcggg acattgggcg gattcaaagt ccgttggatc ggatgagcgg
    16621 gcaggaggat tgaaccgcag aaagtgcggg aatagggaga aaagtgcagg attcacgaag
    16681 ttcgtgaata tgacgaagag agcattcttt cggaagttcg taaataagac gttataggaa
    16741 atcagcgcta aaaactaaaa aattaaaata cagaaaatat tatttaggag acaacaaaaa
    16801 tatgaacaat aagtttgtta ttgctctagt ctgtgtcatt acttttttag caatatttcc
    16861 attcttcatt aatgtatcat ttatgggatg gaggacatca attacatttg gaagtactga
    16921 atcttggata ggattttttg caagttattt tggagcgatt ttcggtggag taatcggcgg
    16981 gttatttaca tatcttggtg taagacaaac aattaacaca caaacgaagc aaaaatatat
    17041 tgatgagttc cctgagaaga ttaaacttct gacggatgtt ctttttaaac ttaaaggtca
    17101 gcgtgattct tttaataata acgaatactt tattaaaggt ttagcacagt atgaacgccc
    17161 gtcagagtat tttgatttaa tgtcaagtac aatcagttcg gctgcagaat caggaaataa
    17221 aattgacggc gctctttatg aaaaaatgaa agaaatcaga gaacgaaaag acaactgtat
    17281 tcttaaatca gctaaccatc cattaatttc actcgtaatt gctgatgatg agtttggaac
    17341 aaacgccaga gtatctttag aatcaattaa ttttagacga caagtgcagg ctgaaataac
    17401 tcaaataatt aatgatctta tatcaatttt tgaagatcaa ctgattaaaa tggaacagaa
    17461 attcaagcaa tatataaagt aattagtttg aagctgttcg aagaaggcgc tgacatccta
    17521 taacataata ttcacgcatc gtgctacgcc ctcggtccca gaagttgatt caaggaagct
    17581 gttgctgtgg acacactcga cttcgtcgag cgtcgtgaat acaggaacgt tatatgcaac
    17641 ctgaaagact gggaaatcat aggtgaagaa taagataacg aagcgccgag ttccctatcg
    17701 gcgtttttgg tttagggtaa aagtatttga aaaatcaaag gaatttacag atctaagaac
    17761 gattaaagca cggggccaag agttgaaata ggaagcacgg tgtcgcttcc gatcagacga
    17821 atgaagaaag ggaatttgga aagcatttca aaccgaaggg gatttgaaaa agatggagga
    17881 agagctaaaa aatcattggt gaaagacaga aagaaagcat agaattgaag aaggggaaga
    17941 tcgaataaga ttaagaggat ttggaaggac ataggcatta tctaacataa tattcacgct
    18001 gcgggcataa gcccttagtc tagcattcgc tagacactcg acatgtatct acgcctttgg
    18061 tccgacagac gccggacact cagcatgcga taagttgtga atacaggaat gttataggat
    18121 attattttct catctgaagg ttttgtttaa ctttatgaaa acaattaaat gttgatattc
    18181 aaaataaatg agtaataaac tagctggagg cgaagtagat tatgggcaga aaaattagtg
    18241 atcacgttca aagaatgttg tatgccgaat caatggggcg gtgtatgaac cctgattgta
    18301 aggttgagtt gtttagagat aatggagaca taattgagaa agcgcattta acgcccttct
    18361 gcgattcaga agataactca ttcgaaaatt tagtagtcct gtgtccaaat tgtcatactg
    18421 attttgacaa gaattctgca ttcacgaaag ttcacgtgac aatgtggaaa cagaatagaa
    18481 aagaagaatt tgatagattt tttggtgaaa aatttagtac atttgatgaa ctcagaagta
    18541 gagtggctcc attactgaaa gaaaataaag taatttttga aaactactat attggtgata
    18601 aaaaagaact ttggaacgtg tttgaaggta agattttagc aaataataat atgttaaaga
    18661 agttgcttga gcaaaatcga aatttaattc aaaggcatag cgatgaaagt tactcaaatt
    18721 tagcgataat tgacacattt cttgttcata tatccgaatt tgaatcaact agacctactg
    18781 ttgaaaaaca tagacaggtt ctgttcccag aagagataaa ctctttgttt ggaatagaac
    18841 ccgtcgatca gtcactatta ccctcagttg agtcgttaga aatattgata aataagctac
    18901 aaaggcaagg tgaattcgta gggatagttt taggtactga taatccatac atagagcttc
    18961 tcgaagatgg taatgtggtt aaattgtatt taaatgatac acctagacta agacaattct
    19021 attttgacta tggttgtttt cggggagcga aagttcgatt ggacagttta aactttgctt
    19081 ataaatttat aaaaactaga ggtgttatgt ttgagtttaa tgattacact aatttgagag
    19141 aggttatagt gaaagggaaa aaaatgatct tcatttataa ttactgtctc agtaaagtag
    19201 acctaatgaa actaactcca tctgaaaata gcattctagt aaatctacac aattggaatg
    19261 gtaagggatg tatatcgagt gaagcttatg ctttggctga cgaaatggct gtcacattat
    19321 taacaatgga taaattttat gtatacgtta atagacttaa ataagattta taaaatttac
    19381 tatagttttg ttcaacatca gtccttgttt gattcatttt caaatgtata cttatttggc
    19441 tcgatattat ctttgaataa gattctaaac gatgttgata ttttattagt atacgatgaa
    19501 ttaacaaata aggttttata tgattctgag gaaataagtt ctattatgta tgaatatagt
    19561 ggaattcaga ttgatatgac tatattgagc caaaatgaat tcgaagaaac ggattttttg
    19621 tgtaagctaa gaggtaaata tttgaaaatt aaataaagtg aaatatgtct tcgattgtat
    19681 gcatttgtat attaaacgaa acaaacatcc tataacacga caatttacta cattccttcc
    19741 gattcacagc tgttacgaag caagtactgc gccacttttt ttgctgtggc ataaaaagga
    19801 aggaacgtcg ggaactgcgg aaacgttcta tgtaacctga aaaactggga acccatgagg
    19861 gaaagaataa gattgcaaag cgccgagttc cctatcggcg ttttttgttt aagattaaaa
    19921 acatttaaaa aatcagaacg atttacagag ataagaacga ttaaggcatg aagtccagat
    19981 ttgaaatagg aagcacggag tcgtttccga tcagacgaat gaagaaaggg agtttggaaa
    20041 gcattttaaa ccaaaggaaa tttgaaaaag attgaggaag agctaaacaa tcgaggaaga
    20101 actaaaaaat cattggagaa agacagaaag aaagcataga attaaagaag gaaaagatca
    20161 aataagatta agagaaattg gaagagcaca ggcagcatat aacataatat tcacgctgtg
    20221 agcattcgct tttggtccga catgcgtcgg acactcagca tacgctgagt cgtgaatacg
    20281 ggaacgttat cagaaatcag cgtgaagtgg gtgaataaat gaatagaggc ataagttttg
    20341 aaattccaaa ttcttatgga agccatcttg gagagatttt aaagccaata gatataacta
    20401 ctttcagttg gtttattggt ggagaagagt catattttat tgttgatgat actttagggg
    20461 gtaatctctt tccagacatg gttactggaa tggatggaga agatcttaaa aagattattg
    20521 attacaacaa gtactactta atatttgcga atttaaaggc gtatccaaaa ggagcaaata
    20581 taatagatgt aatgtcatat gaagaatata ttgcgagtga gtgtcagatt attcttcttg
    20641 tgattgatag tgtgtacata acagtttact gcaaagacct tgaaaaactt gaggacttat
    20701 atgatcacat aaagagaaag ggatataaat ctctggaata tataactgat gaaaatgata
    20761 caaggacaag actatcagtt tggtgattaa aaacaaaaaa tgattgttgt aagtaattca
    20821 aggaagacgc tgaaatatga taacataata ttcaagctgc ggctctaatg gagccttggt
    20881 ctgcggtgaa tttcggagag gcatttcagc agacaacccc gttggggttc atgaatatag
    20941 aaacgttatc tgaaatcagc taaatcatag acacttaagt aatgaggtga acacctttgg
    21001 atggacacca gataatgtta caactaattt tattctttca tttattgctg cttactttat
    21061 ttcagataaa ttaactaaac ctaataaatg actaataggt aaacacctga gcagcgaaca
    21121 aaatttatat tagaggaggt cacaggatga acaagcatag tgtttatgaa acaaacagct
    21181 tctattggga tacaaaagga aatgactttt taggagcaat cgtacttcct ttttatggag
    21241 catttgtctc agaagaaaaa tgccaacttt ttggcgatgt ctcaggaaaa aagatgttag
    21301 agataggctg tggaaatggt caatccttgc aatatcaggg ggatcgcaaa gcatctgaac
    21361 tatgggggat ggatatatca gaaaaacaaa ttgagaaggc aaaacaacat ttgacggcgt
    21421 gtggtctttc ggcaaaattg atctgttctc ccatggaaga agaatgtgac atacctgtag
    21481 attattttga ctttgtttat tcgatttaca ccataggctg gacaaccgac ctagaaggca
    21541 ctttttgtcg aattgcttct tatttaaaaa aagactgcgt ttttattttc agttggtctc
    21601 atcctataca caaatgtgtt gttgaagaaa ataatagatt tgcttttaac aagtgttatt
    21661 tcgatgaatc ttggtattcg gtatctcctg atttttgtca aggcgcgcta accttatctg
    21721 accgtaaact atcaacctat ataaatgcgt tggcgaaagc agggtttgtt attgaacaaa
    21781 tgattgaaga aaccgagaat gaaatcatac aattgcacga tgaaaataat gatttcgtaa
    21841 aaagagcgaa gatgtttcct gtaaccttcg ttatcaaagc aagaaaactt taaaattact
    21901 gaagaagctc aaaataagtg agttagtggc tctaaggagg gctgacatca gataacatta
    21961 tattcacgca tcgggcatac gccctcggtc cggcaggagg atttcgggga agcgggggca
    22021 gccggacaca cccagcattc gctgggcgtc gtgaatacgg gaacgttata cgaaatcatc
    22081 ttacataaga ggagaccaaa tatgaattct aatgattttt catggaaaga agtctattca
    22141 tactggaagc actttattga agagtatagc tatagatcta ttgacgaaca aagttttaaa
    22201 aaaatttaaa taaaaccaca gttaaatcct aatcttaata ttggaactga aataatagat
    22261 tggtggccaa ccaatgaagt tgaatataga acaaagaaac taaatgatcg aggcatttta
    22321 ggtgctgatt gggatacagt agtcggtttt aatcgaacag ctgaaatgtt atggaacaac
    22381 aaagaaag
//
