LOCUS       NZ_POVS01000014        20237 bp    DNA     linear   CON 15-SEP-2024
DEFINITION  Paenibacillus sp. F4 F4_contig_13, whole genome shotgun sequence.
ACCESSION   NZ_POVS01000014
VERSION     NZ_POVS01000014.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. F4
  ORGANISM  Paenibacillus sp. F4
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 347813)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Genome sequencing and comparative analysis of polymyxin-producing
            Paenibacillus strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 347813)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2018) Infectious Disease Research Center, Korea
            Research Institute of Bioscience and Biotechnology (KRIBB), 125
            Gwahak-ro, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-JAN-2018
            Assembly Method                   :: CLC Genomics Workbench v. 11.0
            Assembly Name                     :: F4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 524.4x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002894905.1-RS_2024_09_15
            Annotation Date                   :: 09/15/2024 04:37:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,419
            CDSs (total)                      :: 5,299
            Genes (coding)                    :: 5,203
            CDSs (with protein)               :: 5,203
            Genes (RNA)                       :: 120
            rRNAs                             :: 10, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 102
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 42 of 96
            Pseudo Genes (incomplete)         :: 67 of 96
            Pseudo Genes (internal stop)      :: 14 of 96
            Pseudo Genes (multiple problems)  :: 22 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:44:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 221846
            Orig. end                         :: 242083
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            POVS01000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20237
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="proteusin"
                     /region_number="3"
                     /rules="(PoyD or TIGR03793)"
                     /tool="antismash"
     cand_cluster    1..20237
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /kind="single"
                     /product="proteusin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20237
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10237](+)"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10237
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
     gene            692..1918
                     /locus_tag="C1T21_RS16245"
                     /old_locus_tag="C1T21_16245"
     CDS             692..1918
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309078.1"
                     /locus_tag="C1T21_RS16245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16245"
                     /product="acyltransferase"
                     /protein_id="WP_103048978.1"
                     /transl_table=11
                     /translation="MSKPRIAEWTELRGLAYLAVVLQHCIGEYIYRSDIQQPDSVMLAM
                     LYHLTRFGTPTFVFLSAALLFYNGNKPIGYPRYIGRRFRDIYVPFLCWTVIYWVCTQNW
                     STAQWGNIYFYKGMFEEMIIPVSGYHLWFVVMIFQFYILFPLFAKAAGQVQAFLRRYST
                     KRRKQLVLAIMLIAATAYALLLQWSYYDMSAWSTGLPSFWQTLLDYRTYNFVMYFFYFM
                     LGAVCAYMTNTWRGLAKQTLPWNVFVFIGLFMLMGHTMLIQSGDTINLNISTYLKPSTF
                     VLIVSQLLLLYGLLLHLQKDTRSEPFRRMLNWIGRYSFGGYLAHALVLSFISYYTRPLA
                     LGDHHFTATLITFVVVASVSLGISWLLAHLPGGNWIVGSKGRQRLNWHSFRFQFFSSKR
                     ASKSTQELG"
     gene            complement(2184..2369)
                     /locus_tag="C1T21_RS16250"
                     /old_locus_tag="C1T21_16250"
     CDS             complement(2184..2369)
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280170.1"
                     /locus_tag="C1T21_RS16250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16250"
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_103048979.1"
                     /transl_table=11
                     /translation="MNRYETVTLIQQVENARQQLHDLYEEYGFGHACVLEQSMLLDELI
                     NQYNRMFQTKKLPHYV"
     misc_feature    2386..2400
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.01"
                     /tool="antismash"
     gene            complement(2595..3992)
                     /locus_tag="C1T21_RS16255"
                     /old_locus_tag="C1T21_16255"
     CDS             complement(2595..3992)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821361.1"
                     /locus_tag="C1T21_RS16255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16255"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_103048980.1"
                     /transl_table=11
                     /translation="MEITPTIQAEIQTYLKRKGLTMTKFGHTIDLNVGTVSSIVTGNRS
                     ISVHQLDSITAGMNLPPDYFYERYIEECIEESPLNWKKISPFLYRCIELGRLDCLQRVV
                     ILLLDNPNYPPSLFEVAENVYKDGYNEAAAYLYKKVAESEKQQHSERLAICQYRLFQIN
                     IGQDRAINLQAAIEFAPFVDRLDEIEQLDALKDLANVYRSLSMWDKVYEFAHQMGQMGK
                     IQYNLVHNSKRKGTEPRKKLSRPLFVYIVYSELLCANACDAKGDHEQALEHIRGYADLS
                     WVKEKDPDSLYWKKQYQQWAKINTYVNRLMSGDISVLPDYVEHMAAENEIFAELLNVLE
                     VANRYNVDVDHILQRFESQIEAYQEPSSSDMYTQQVLPEEYVRFWYKMAKYSLNKGRYL
                     YGFKCLINAFEKAVTINHVLLIANCFGLFFHFKTHAAPETQTQFQSIYEEVWEKNDQKD
                     GFLLGGN"
     gene            4179..4646
                     /locus_tag="C1T21_RS16260"
                     /old_locus_tag="C1T21_16260"
     CDS             4179..4646
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369729.1"
                     /locus_tag="C1T21_RS16260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16260"
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="WP_103048981.1"
                     /transl_table=11
                     /translation="MEGEDHLKNTGMTRPLDTLGRIVIPKELRTSMGIQAGESLEFYLD
                     VETGLLSMRKYIGVCCHLCYSIQDLSYFRDSFLCKKCINDLKGNIGVSPLPVPVVKKPA
                     YKEKSNHRSSSQHLVENLRKLMREHPTAKQGEYAEWLGVSQGRISQLKKLL"
     gene            4860..5318
                     /locus_tag="C1T21_RS16265"
                     /old_locus_tag="C1T21_16265"
     CDS             4860..5318
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010347576.1"
                     /locus_tag="C1T21_RS16265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16265"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_103048982.1"
                     /transl_table=11
                     /translation="MKTTGKNKKSSQERSASVCTCINLRRSSMAITGLYDRYLAPSGLN
                     ISQFSLLKHLTALGPASVSELALEMRLDRTTIVRNLKALEHSGYVEDTSAEGSRNRCLT
                     LTESGRTVYNDAAELWEEAQRFLQESLGNGNLQILTSLLSKIENLDGY"
     gene            5578..6453
                     /locus_tag="C1T21_RS16270"
                     /old_locus_tag="C1T21_16270"
     CDS             5578..6453
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369171.1"
                     /locus_tag="C1T21_RS16270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16270"
                     /product="(Fe-S)-binding protein"
                     /protein_id="WP_103048983.1"
                     /transl_table=11
                     /translation="MVESVPDMRENIAAEMKTYVSEDKGNVCEELQSPYYEEPIIQFAA
                     ANDPLFEEYKRVVGPDHATPQEAFERSFGTGSFDGGTVISVVLPISETIRKANRAQKER
                     ASREWALLRTFGDEYFVQSARRHLAGYLTGLGYRAFAPLDTDWYSIHGAEGGPISNWSE
                     RHIAYAAGLGTFSINDGFITEKGIAIRLLSVVTDLKVPPDARISATGHTGNCLLCSKGI
                     CGVCITRCPVQAISKDGGHDKIACMNFVYGQASRDFAVLNGGEAKSGAGCGLCQTKVPC
                     ESRNPMRTAR"
     gene            complement(6510..7022)
                     /locus_tag="C1T21_RS16275"
                     /old_locus_tag="C1T21_16275"
     CDS             complement(6510..7022)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429111.1"
                     /locus_tag="C1T21_RS16275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16275"
                     /product="hypothetical protein"
                     /protein_id="WP_103048984.1"
                     /transl_table=11
                     /translation="MKKQWKLTAAILYGGVMMYGTAGAAGASGTEPSNSLQTLTPNDFI
                     QGAARQWNAEPQDDHGHGHVHRHRHGKRPGGLNHHLNEKVAKLLGITPVQLEKELGQGK
                     SLAEVAKSKGIQEDQLIDKLKNEMTVDLKRLVNRKGPITFDRKSGASNEAQLKHEAGTP
                     STSANEN"
     misc_feature    complement(7217..7235)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.12"
                     /tool="antismash"
     misc_feature    complement(7288..7299)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.09"
                     /tool="antismash"
     gene            <7416..7613
                     /locus_tag="C1T21_RS28045"
                     /old_locus_tag="C1T21_16280"
                     /pseudo=""
     CDS             <7416..7613
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003238262.1"
                     /locus_tag="C1T21_RS28045"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="C1T21_16280"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="SKRTSKTISVSEHFKKWEDMDKMYEASLTV"
     gene            7739..8812
                     /locus_tag="C1T21_RS16285"
                     /old_locus_tag="C1T21_16285"
     CDS             7739..8812
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369725.1"
                     /locus_tag="C1T21_RS16285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16285"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_103048985.1"
                     /transl_table=11
                     /translation="MFIAKAGKWTAIMSITLSLFTGSLVISSNQALAADCSSGYVALTF
                     DDGPNPSNTKALLSALKQNGLRATLFNLGQNAQNNPSLVRDQQAAGMWIGNHSWSHPHM
                     TQLSTSQMSSEITRTQQTIQSITGTAPKLFRPPYGETNATLKSIETQNGLTEVLWNVDS
                     QDWNGASTAQIVAAAGKLKNGDVILMHDQYQTTLQAIPQIAQNLKNRNLCSGMISPSNG
                     RAVAPDGGNGETPPNKGTKVEAENMTKGGQYTSNISSPFNGVALYSNNDSVKFTQNFTS
                     GTHSFSLRGASNNSNMAKVDLKIGGQTKGTFYFGGSSPAVYTLNNVSHGTGNQEIELVV
                     TADDGTWDAYIDYLEII"
     misc_feature    complement(8816..8825)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    8881..8895
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.42"
                     /tool="antismash"
     misc_feature    complement(8906..8918)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.58"
                     /tool="antismash"
     gene            8990..9925
                     /locus_tag="C1T21_RS16290"
                     /old_locus_tag="C1T21_16290"
     CDS             8990..9925
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429108.1"
                     /locus_tag="C1T21_RS16290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16290"
                     /product="hypothetical protein"
                     /protein_id="WP_103049058.1"
                     /transl_table=11
                     /translation="MEWYFAYKDELEKVFRQAEERTSTFPAPFQQEGLDYLARFNPLRE
                     DSTRNYICYLLPFWLQELTGLPPKTCRKLSLGNVFVMAHYLIQDDVMDTAADNRKTQLA
                     LSQLFYTECLSVYRDLFPATSPFWSYARTYVDEWAVSVISEGTEDYFQGERNKVALKAS
                     PLKMAGTGALLLAGRADLIQTITNMTDLALLVLQMSDDWADWSEDLVEHSYNCLLSHIS
                     AEQKTAYCEGLGPQQIQEAIYVRGALASYVNIADQAVQQLETLEPSIHGLRSFAHSITA
                     ELGEVAAEIEGGRSHLRRGGLDYWLSKNMK"
     gene            10001..10237
                     /locus_tag="C1T21_RS16295"
                     /old_locus_tag="C1T21_16295"
     CDS             10001..10237
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429107.1"
                     /locus_tag="C1T21_RS16295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16295"
                     /product="NHLP leader peptide family RiPP precursor"
                     /protein_id="WP_007429107.1"
                     /sec_met_domain="TIGR03793 (E-value: 5.3e-21, bitscore:
                     68.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATEVLQTQVIQKAWEDASFREKLMTDPKSAIRDVLGVVIPDHIQ
                     IKTLEETPDQFYLVIPPDPSGVLAASQKPRSMW"
     gene            complement(10337..12226)
                     /locus_tag="C1T21_RS16300"
                     /old_locus_tag="C1T21_16300"
     CDS             complement(10337..12226)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686330.1"
                     /locus_tag="C1T21_RS16300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16300"
                     /product="sensor histidine kinase"
                     /protein_id="WP_103048986.1"
                     /transl_table=11
                     /translation="MRHVPKAVAALLAVIVILLSLGHSTYAAKMTPERDYKIPSWDMRW
                     GAVNEDGSLDEVKDPSKVWMHIEDDTQLLRQPGNKGSAWIRMKLPSLNDETPAVLFENI
                     YGRHITLYKDGTNFYESYRGYNYENNRILIPLKPEDSGKTLYIWTESSKNRLGIIGNVM
                     TGDYRDLLGTLVRMDVLDIVLGSTFIFIALVLLICSFFLFRPSMAMWLSLSAIVLSIGL
                     MIVTYSPFLYTFYRGYGKLYLQLFDVALFILLPSLAYFFEQNINSIILIRKFRKLLTAY
                     SLFCFTMMIVNLGAQERLNDIYYFFSVVILGILLVALMILLVFASVRMALKGDHEAIIL
                     STGFAFFAVISIGELSWFFILDGHYNMFLWKWGVFGFVLALIAILGRRLAEKHKQVVRY
                     SRELEMFNNELQRSEKMEIISDLAASVAHEVRNPLQVTRGFLQLMSKQEDGKNKDYLHI
                     ALEELDRASAIITDFLTFAKPEFDQTKTLTILDEFKHIEGIISPMANLQGGKISLDIPQ
                     EIKVRGNSSKFKQAFINIIKNSIEALRDQGHIHIWAYVDNGEAVIHIRDNGEGMDAQTL
                     SRLGEPYFSNKTKGTGLGMMVTFRIIETMNGKITFTSAKGVGTEATIRFPVAG"
     gene            complement(12359..12646)
                     /locus_tag="C1T21_RS16305"
                     /old_locus_tag="C1T21_16305"
     CDS             complement(12359..12646)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369721.1"
                     /locus_tag="C1T21_RS16305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16305"
                     /product="hypothetical protein"
                     /protein_id="WP_103048987.1"
                     /transl_table=11
                     /translation="MEWYMFGPMISRIRVGQKASTPGFSRTLIRRPEGLYWTDGGQAGK
                     IVEIRDYLFSDIWTIYEDEDSEPWLGLREQKERREQEMIINQYEDFTKNE"
     gene            12830..13090
                     /locus_tag="C1T21_RS16310"
                     /old_locus_tag="C1T21_16310"
     CDS             12830..13090
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369720.1"
                     /locus_tag="C1T21_RS16310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16310"
                     /product="hypothetical protein"
                     /protein_id="WP_025723196.1"
                     /transl_table=11
                     /translation="MANRDDRTTELHDNDFEPSLQNAETNWENLTEGPDTPLEDVPDAD
                     ELTPNSPVDPSAPAEFLHGTDLLNGTDGDEEEQLDSDDMLD"
     misc_feature    complement(12865..12879)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.27"
                     /tool="antismash"
     gene            complement(13457..14128)
                     /locus_tag="C1T21_RS16320"
                     /old_locus_tag="C1T21_16320"
     CDS             complement(13457..14128)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009595536.1"
                     /locus_tag="C1T21_RS16320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16320"
                     /product="GNAT family acetyltransferase"
                     /protein_id="WP_103048988.1"
                     /transl_table=11
                     /translation="MEYHRITHIEDPLFASMHQLMQEVFPPEEVLEYSLWKEPLEDPGI
                     RVFVAVQDDKVVGATEYRYYEDFNVAMTDFTVIGQPGLGIGRFLWTRRQNDLHALAQAS
                     GQQLQGMFAEIYDPYRGNEHTFGGVKPMDPYVRREVLSHLGYKRLDLDYVHPSWNNDGV
                     AVEGLNLGFMPEDDSVEEVSAELVAAFLRRYYTVLPNKPAAWNEMVEGLEAKSTVVLLP
                     L"
     gene            complement(14148..14819)
                     /locus_tag="C1T21_RS16325"
                     /old_locus_tag="C1T21_16325"
     CDS             complement(14148..14819)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280151.1"
                     /locus_tag="C1T21_RS16325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16325"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_103048989.1"
                     /transl_table=11
                     /translation="MYRKEWFIFDGDRPLRAVIRNYSTADYEGLLRIQLESFPPPYPQE
                     LLWSREQIASQIEHFADGALCVEIEGELAGSVTSLLMHYNPEHPQHTWEEVADDGYIRT
                     HCEDAKALYVIDLAVRPAYRRLGLGKWLIFSLYHLVIERRLDRLLGAGRMPGYQHHADQ
                     LSAEAYVDAVVSGELKDPVLTFLLRCGRVPVCILPNYLDDEQSRNYAALMEWRNPFHTH
                     H"
     gene            complement(14836..15696)
                     /locus_tag="C1T21_RS16330"
                     /old_locus_tag="C1T21_16330"
     CDS             complement(14836..15696)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280150.1"
                     /locus_tag="C1T21_RS16330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16330"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_025723200.1"
                     /transl_table=11
                     /translation="MSKIRVSAVQYHLHTIDSFEQFALQSEHYIKTAEEFGAEFVLFPE
                     FFTTQLMSIGESKGKALTINDLPDFTDRYLELFTSFARRTGMHIIGGTHVIRRNERLYN
                     TAHLFYPDGRVATQDKIHITPTEVHEWNMAPGEGLNVFETSKGTIAMLTCYDIEFPEIV
                     RMAKAKGADIIFCPSCTDDRHGFYRVRYTSHARAVENQVYVVSTGTVGSLPTVDFMRAN
                     YGQAAVITPNDIPFPPRGIMVEGELNNDMIVTADLDLQLLYDVRERGSVTTWRDRRTDL
                     YTDWS"
     misc_binding    15858..16129
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     gene            16216..17298
                     /locus_tag="C1T21_RS16335"
                     /old_locus_tag="C1T21_16335"
     CDS             16216..17298
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0046417 - chorismate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369718.1"
                     /locus_tag="C1T21_RS16335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16335"
                     /product="bifunctional 3-deoxy-7-phosphoheptulonate
                     synthase/chorismate mutase"
                     /protein_id="WP_013309063.1"
                     /transl_table=11
                     /translation="MSTNENSLELLREQLDATNLQLLELLSQRAELAGQLGKLKEAQGV
                     PDFDPVREQQMLDKLIAANRGPFDDATIRQLFKNIFKASLNYQKEEHKKHLIVSRKNQP
                     DSTVIKVKDTLVGGKASIMVAGPCSVESYQQTREVGAALKEAGVPILRGGAFKPRTSPY
                     DFQGLGVEGLQILKRVGDEFGLATISEIVDPRHLEEAIQYIDIIQIGARNMHNFELLKA
                     AGETRTPVLLKRGLAATMEEFLHAAEYIVSRGNTQVMLIERGIRTYEKWTRNTLDISAV
                     PILKKESHLPVLVDVTHSTGRKDILAPCAKAALAAGADGIMVEVHPNPAVALSDAQQQL
                     NIPEFHNFLSEVKESGLFKA"
     misc_feature    complement(16218..16233)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.59"
                     /tool="antismash"
     gene            17533..19158
                     /locus_tag="C1T21_RS16340"
                     /old_locus_tag="C1T21_16340"
     CDS             17533..19158
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429103.1"
                     /locus_tag="C1T21_RS16340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16340"
                     /product="DUF1593 domain-containing protein"
                     /protein_id="WP_103048990.1"
                     /transl_table=11
                     /translation="MRERKGLSIFLLAMICILIISGCSGGKAPAVAKDESAAPAKEQVD
                     NKVETKATKARTVITTDGEVDDMNSVIRFLLYSNEMDLSGIVLTSSVYHYAGDEKAGIK
                     PFRWTGTQWVTDMIDAYGEIYPNLTKQAEGYPKPEYIKSVTKIGNISYKGEMDKETEGS
                     NFLKNLFLDDDKRDLYVQTWGGTNTTAKALKSIEDEYKNTAQWADIQKKVSDKLVLYII
                     LDQDDSYNKYIAKNWPDIRIINDQSNFWHFAYAWKMHTEEVNSKLHGEWNFKNIKDGHG
                     KLLNMYALMGDGNIIKGELDEEQRGSEAYLKKNPQYDKYDFISEGDSPSFFYLIDNGLR
                     SMENPSYGGWGGRFGVVNDKLFRNTVLDYDVHTKKFEAEYSLMRWFDDIQNDFAARADW
                     AIASDYKDANHNPTLTIKEGLDLTASPGEKITLHAEGSDPDGNQLTYKWWRYFEADTYE
                     DSKVKPAQVKPELLGEMQLGLHREVAKGEKVNTIDLQGSDTNAVSFTVPADAKSGNTLH
                     IIAEVQDNGKHPLKHYQRVIVTVK"
     gene            complement(19245..20105)
                     /locus_tag="C1T21_RS16345"
                     /old_locus_tag="C1T21_16345"
     CDS             complement(19245..20105)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369717.1"
                     /locus_tag="C1T21_RS16345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_16345"
                     /product="TrmB family transcriptional regulator"
                     /protein_id="WP_025723203.1"
                     /transl_table=11
                     /translation="MKPKPNILEILRDLNFSEYEAKAYVTLLESSPLSGYAVSLNSGVP
                     RSKIYEVLSGMVNRGDIMVSQENTPLYVPLPPHELIAQRKRKAEQIFNVAQESLEQYTA
                     SFQNRENIWNISGYEAIINRINEGVKGAKHRILLEIWKEDAEVFRDALEQVAQQGIEVI
                     IVAYGELNFDFANVYRHDMSEEITSEIGGRWIVLSVDDREVVAGILSLGDDSRAAWTLH
                     PGLVMPITEVIIHDIYIMEILYEFREQLEAKFGPNLIHLRNKFAMGPNGKGYYVPLTEK
                     SIKRV"
ORIGIN
        1 attttatccg cagcggtcac gcccgcctta taattatccg tgcccaaaaa ggaatacgcc
       61 cggctccccg gcgcttcggc atcaaacagc accacaggaa tgcccgcatc cagcgcctta
      121 ttaatcaccg gaatcaaaga gtgaggatca atcgcggaaa tcgcaatccc tgcgggttta
      181 cgagcaattg cttgctcaat aacagttgtc tgctcctgcg catcataacg ggtagctccc
      241 cgatactcca cagtcacccc caaagcatcc ccggcatcct cgaagccctt aagcccgctt
      301 ttccaatact ccaaaccaga ctggaaggta atcatcatat aagtttctcc gatgctgcct
      361 cgcagcccct tatcctccca agtgccattc aacgggcccg tttgttcata cctgaacaca
      421 tagagagcaa aggccgcaat caacagcata tataccagca gcgttttttt catcctccct
      481 ctcctcttcc tgtgtgtatc cttaagttat aaattcactt taatttattc tggttttact
      541 tagattgtaa acgcaatcat attaaattgg aactacttca ctcttcttac tttcaggtgg
      601 cgttaatcct gcactaatgt ttctacgtta caatacctac aattgtgcta ggaaaaacat
      661 gtgcgtatct tgcggaaaag gagtgatatg gatgagtaag ccgcgtatcg cggagtggac
      721 agaactacgg ggccttgcct acctcgctgt cgtgcttcag cattgcattg gcgaatatat
      781 ttatcgcagc gacatccaac agccagattc tgttatgctc gcgatgctgt atcatttgac
      841 acgttttggc acaccgacgt tcgttttcct gtctgcggcg ctgctttttt ataacggcaa
      901 caaaccgatt ggctatcctc gctatattgg caggcggttt cgagatattt atgttccttt
      961 cctttgctgg actgttattt attgggtatg tactcaaaac tggtcaacgg cgcagtgggg
     1021 aaatatttac ttttacaaag gtatgttcga ggaaatgatc atccccgtta gcggatatca
     1081 tctatggttt gtagtgatga tctttcagtt ttatattttg tttcctttat ttgcaaaagc
     1141 agccgggcag gttcaagcgt ttctacgtcg ttacagcacg aaaagacgca aacagcttgt
     1201 tttagctatt atgctgattg ccgctacggc ttatgctttg ctgttacaat ggtcctacta
     1261 tgacatgtct gcatggagca ctgggttgcc gtccttttgg cagactctgc tggattatcg
     1321 cacctataac tttgtcatgt actttttcta ttttatgctg ggcgcagtat gtgcttacat
     1381 gacaaacacg tggcgtggac tggccaaaca gacgttgccg tggaatgtat ttgtgtttat
     1441 tggtttgttc atgcttatgg gtcacacaat gctgatccag tcgggtgata cgatcaatct
     1501 caatatttct acttatctga aaccaagcac cttcgtgctg attgtctcgc agttgctttt
     1561 attgtacgga ctgctactcc atttgcaaaa agatacgcga tctgagccgt ttcgccgtat
     1621 gctgaactgg atcggacgtt attcttttgg aggatatctg gcccatgcgc tcgtgctgtc
     1681 cttcatatcc tactacaccc gcccacttgc actgggcgat catcatttta cagctacgct
     1741 cattacgttt gtcgtcgtgg caagtgtttc tctgggcatc agctggctct tggcccatct
     1801 gcccggcggc aactggattg ttggctctaa aggcagacag cgattgaact ggcactcgtt
     1861 tcgtttccag ttcttttctt ccaaacgtgc ttccaaaagc acgcaggaac ttggctaatc
     1921 ttgtgtgtct gtgtttcagc atggggttat aattccaatg gactttggca gggctcactt
     1981 attgagctct gctttttttg ttgccttagt atgccgttcc ctcaaaaaag tgattaacat
     2041 tttatgacat gaatatgtat tttattttaa aataagtcat tatatagaat aataataaac
     2101 attacgcggg agaagtcata gttttgcata aaaagaaggg ggaatgaacc gaacataaca
     2161 tcgtcgttgt taatgatcta gctctaaaca tagtgaggca gcttcttggt ctgaaacata
     2221 cggttgtact gattaatcag ttcatccaaa agcatagact gctcaagtac acaagcatgt
     2281 ccgaaaccat actcttcgta aagatcatgc aattgttgtc tggcgttttc cacctgttga
     2341 attaacgtaa ctgtttcata cctgttcatc ctgcatacct cctaatgaat ctcattttaa
     2401 ggagggatgt acaaatacgt catatctttt ttgagccgaa aaattacaaa ataatacaaa
     2461 aaaagaccag caataagctg gtccatggta atgaattagt gtttggtcaa gatccaccaa
     2521 cgtgtccttg tgtttggatc gtgccatggc ttagatttcc agcttggact ggtactgtga
     2581 ataccagtaa aaagctagtt accgccaaga agaaagccat ccttttgatc atttttctcc
     2641 cacacctcct cataaataga ttggaactgt gtctgtgttt cgggagccgc atgtgttttg
     2701 aagtgaaaaa ataatccaaa acaattggca ataagtagta catgattaat tgtaacagct
     2761 ttttcaaacg cgtttattaa acatttgaaa ccatataggt atctgccttt atttaggctg
     2821 tacttagcca ttttgtacca gaagcgtacg tactcttccg gtaaaacctg ctgtgtatac
     2881 atgtctgaag atgacggttc ttgataagcc tcaatttggg attcaaaacg ctgaaggata
     2941 tggtctacat ctacattgta ccgattagca acttcaagaa cgtttagtag ctcggcaaaa
     3001 atctcatttt cggcagccat atgttctacg taatcgggga gaacactaat atccccggac
     3061 ataagcctat tgacgtaagt attaattttc gcccattgct gatattgttt cttccaataa
     3121 agtgaatcag ggtccttctc ctttacccaa cttagatcgg cataacctcg gatatgttct
     3181 aatgcctgtt catgatctcc ttttgcatcg caagcattag cacacagcaa ttcggagtaa
     3241 actatgtata caaacagtgg cctgcttagc ttttttcgtg gctctgttcc ttttcgctta
     3301 gagttatgaa ccaaattata ttggatcttt cccatttgac ccatttgatg tgcaaattca
     3361 tacaccttgt cccacatact taaggatctg tacacgttcg ccaaatcttt taatgcatct
     3421 aattgctcta tctcgtctaa acgatcaaca aaaggggcaa attcaatggc agcttgaaga
     3481 tttatagctc tatcttgtcc aatattgatt tggaacaaac gatactggca gatcgccaat
     3541 cgctctgaat gctgctgctt ctcactttca gccacctttt tgtaaaggta tgccgctgct
     3601 tcattgtaac cgtctttgta tacattttcg gcaacttcaa agagcgatgg cggataatta
     3661 gggttatcca atagcaaaat tacaactcgc tgcaagcagt ccagtcgtcc tagctcaata
     3721 catcggtata agaaagggct gatttttttc cagttgagcg gagattcttc aatgcattct
     3781 tcaatataac gttcgtaaaa ataatccggt ggtaaattca ttcccgcagt aatgctatcc
     3841 agttggtgaa cagaaataga tcggttacca gtcacaatgc tactaactgt acctacattc
     3901 aaatcaatcg tgtgaccaaa cttggtcatc gttaagcctt ttcgtttcaa ataggtttga
     3961 atttctgcct gtatcgtagg tgtgatttcc atggataaac caccctttca gcattttcat
     4021 agaatttcaa tttcaatttc aataaacaat atagtttgga aactaatagt ataattattg
     4081 attttccttc acgataatac catcttttgg aacaaacata aatgctttta ctttattgat
     4141 ttttatattt ttattaggag atcattggat gttggacaat ggaaggagaa gatcatttga
     4201 aaaatacagg catgacacgc cccttggata cgttaggccg gattgttatc cctaaggagt
     4261 tgcgaacctc tatgggtatt caagctggtg agtctttaga attttattta gatgttgaaa
     4321 caggattatt gagtatgcgg aagtatattg gagtctgctg tcacttatgc tattcgattc
     4381 aggacttaag ctatttcagg gattcatttt tatgtaaaaa atgcataaac gatctgaagg
     4441 gaaatatagg tgtgagtcca ttacctgttc ctgttgtaaa gaaacctgcg tacaaagaaa
     4501 aaagtaacca tcggtcgtct tcacaacatt tagttgaaaa tctaagaaaa ctcatgcgcg
     4561 agcatccaac agccaagcaa ggcgaatatg ctgaatggct cggcgtatcc caaggccgta
     4621 tttcccagct taaaaagctg ttataggtat cgctcaactc atattctagc catgctaaat
     4681 aaccagtcgc tggttgattt cgcgcgactg gttatttcaa cttttcatta gtaggaagga
     4741 ctacagggga taaatcatga tagaccgaca gaactgactg ctgtgacaaa tatcgcttac
     4801 aaaacctacc acttttgaga tggtgtagat acacgaaaca gtacacgaat ggagaactta
     4861 tgaaaacgac aggaaagaat aagaaatctt cgcaggagcg atcagcctca gtctgtacct
     4921 gcatcaatct gcgccgttcc tcgatggcta ttacaggact gtatgaccgg tatctggccc
     4981 cgagcggact caatattagc caattctcgc tgctcaaaca cttaactgcg ctgggaccgg
     5041 caagtgtaag cgaattggcg ctggagatgc ggctcgaccg gacaacgatt gtgcgcaatt
     5101 tgaaggcgct ggagcatagc ggatatgtgg aggatacatc tgctgagggc agtcgcaacc
     5161 gctgccttac tctgacggag agtggaagaa cggtatacaa cgacgcagca gagctttggg
     5221 aggaggcgca acgttttttg caggagtcat tgggaaacgg gaatctgcag atactgacct
     5281 cactcttatc caagattgaa aatttggatg gatattagac ggctcctcat ccaggtggag
     5341 ttgtgttcaa ttcgtgtata tacacgaaaa agatcgaaat gtttattgcg gtatcaaggc
     5401 tagagatgtc tttaaaatgc tattatagcg atcgcattgc atttgatcac cactgcgggt
     5461 catcggagaa gtacttccag ctgtagtaag aggtcagtga tatacattag cccgccacaa
     5521 gacttctgaa gggaagcttt actgtgaaca ataaccacgg agaggaatgt ggataggatg
     5581 gttgaatccg taccggatat gagagaaaac atcgcagccg agatgaaaac ctatgtgagc
     5641 gaagacaaag gcaatgtttg tgaagaactg cagagtcctt attacgagga gccgattatc
     5701 caatttgccg cggctaacga tcctttgttt gaggagtaca aaagagtagt ggggcccgat
     5761 cacgccacgc cgcaggaagc atttgaacgc tcctttggaa cggggagttt tgatggaggc
     5821 accgttatca gcgttgtgct gccgattagc gagacgatcc gtaaggctaa tcgtgcgcaa
     5881 aaagaaagag cctcaaggga atgggcgctg ctgcggacct ttggcgatga atattttgta
     5941 cagtctgcaa ggcggcattt ggcgggatac ttaacaggcc ttggttaccg tgcgtttgca
     6001 ccgctggata cggattggta cagcatccat ggcgccgagg gggggccgat ctccaactgg
     6061 tcggagcgcc acattgcata tgctgcgggt ctcggcacct tcagtatcaa tgacggcttc
     6121 atcaccgaaa aaggaattgc catccgcctg ctgtccgtgg tgaccgatct caaggtgccg
     6181 cctgatgcca gaatatcagc cacaggacat actggtaact gcctgctatg cagcaagggc
     6241 atctgcggtg tgtgcattac ccgctgccct gtgcaggcca tcagcaagga cggcggacat
     6301 gacaaaatcg cctgcatgaa ttttgtgtac ggacaggcat cacgggactt tgcggttcta
     6361 aacggcggcg aggccaaatc gggtgctggc tgcggactgt gccaaaccaa ggtaccctgc
     6421 gagagcagga atccgatgcg tactgcccgg tgaatatgga aaccttgagg accgccattc
     6481 tcaaggtttt ttagtgcaaa aagatacatt tagttttcgt tagccgaggt tgagggcgtc
     6541 cctgcctcat gttttaattg agcttcattc gaagccccgg acttacgatc gaatgtaatc
     6601 gggcctttac ggttcacaag ccgtttcaga tccacggtca tttcattctt caatttatca
     6661 atgagctggt cttcttggat gcctttgctt ttagcaacct cggccaatga cttcccttgt
     6721 cccagttctt tctctaattg gacaggagtg atgcccagca gcttggctac tttctcgttg
     6781 agatggtgat tcaagccgcc aggccgtttg ccgtgtctat gtctgtgaac atgcccatgc
     6841 ccgtggtcgt cctgtggttc agcattccat tggcgggctg ccccttggat aaagtcgttg
     6901 ggagtgagag tttgcaacga attactcggt tccgtcccgg aagctccagc tgcacccgca
     6961 gtgccataca tcatcactcc tccatacaga atagcagcgg tcaatttcca ttgttttttc
     7021 atgttgcaga cccttctttc atccttttta aaataatatt ttcttttccc gctattttta
     7081 ttcatatttt cgcctgttaa gtaaccataa gacgggaaaa aagaaattat gaacattgct
     7141 atcacaatta cacccaacct tcgatctaca cgcgctcctt gggaacccta tcctgtagag
     7201 tgagcaagaa tgaataacta tactttctac aatataactt gaaatttttc aagttatata
     7261 ttaaggaaaa tatgataaaa tcaaattgta aacgtttaca atttgatttt tggaaagaca
     7321 tgttgcatca agctactaca gaatgcactg catcatagtg aggctacagg agaaaagtcc
     7381 aatgaaacaa aaaaataagg ttatttttat ggacatccaa acgcacgagc aaaaccatat
     7441 cggtcagcga gcacttcaaa aagtgggaag acatggacaa gatgtatgaa gcttcactta
     7501 ctgtataggg ataccaaagc agtcggagtg ccaatgtaac tagtaataca attacgattg
     7561 gcggcaataa tggcaccaga aaccaagaga tcgagctcgt tgtaacagta tgacgggaca
     7621 tgggatgctt atattgacta tttggagatc gactaaaatt tcaaatctag taaagagttg
     7681 aatcggttcg gagtatcgga acatccatac tatattaaaa tagctaggag gtagacccat
     7741 gtttatagct aaagcaggaa aatggacggc gattatgtca atcaccttgt ctttattcac
     7801 aggctcgctg gtgatctcga gcaaccaggc gcttgcggct gattgctcga gcggttatgt
     7861 agcgttaacc ttcgacgatg gtcccaatcc ctctaacacc aaagcgctgc ttagtgctct
     7921 gaagcaaaac ggtttacgcg cgacgctctt taatcttgga caaaacgcgc agaataatcc
     7981 ttcgcttgta cgtgaccagc aagcagcagg catgtggatc ggtaatcatt catggtcaca
     8041 tccgcatatg acacaactga gcacatcgca gatgtcatcg gaaattacac gcacgcagca
     8101 aacgatacag tccattactg gcacggcacc aaagttgttc cgtcctccgt atggcgagac
     8161 caacgcaacc ctcaaatcca ttgagaccca aaacggtctt accgaagtat tgtggaacgt
     8221 tgactcccaa gactggaacg gcgcctccac cgcacagatc gtagctgctg cgggcaaact
     8281 taaaaacggc gatgtgatcc tgatgcatga tcagtaccag actacactcc aagctattcc
     8341 acaaattgca cagaacctca aaaaccgtaa cctttgctct ggtatgatct caccaagcaa
     8401 tggccgggcg gtagcgcctg atggcggaaa cggcgaaacg ccgccaaaca aaggcacaaa
     8461 agtggaagca gagaatatga ccaaaggcgg tcagtatact tcaaatatca gctcgccgtt
     8521 caacggagtg gctttatact ccaacaatga ttcagtgaaa ttcacacaga attttaccag
     8581 cggcacccat agtttttcac tccgtggtgc ttcaaataat tccaacatgg ccaaagttga
     8641 cttgaaaatt ggtggacaaa cgaagggtac cttctacttc ggcgggagca gtcctgcggt
     8701 ctatacttta aacaatgtca gccatggaac cggaaatcaa gagattgagc ttgttgtaac
     8761 agccgatgat gggacatggg atgcttatat tgactattta gagatcatct aattttaaaa
     8821 aaacaaaatc ccggcgggat cttcccagcc gggatttttg tctatatcct ttttacaaca
     8881 ttctcaatgt aaaaataaca aaatcttgaa aattgcaatc tgttgtataa tggcgggtaa
     8941 caactagaag tcgctataaa aatattcata agagatgcag gtgatggcga tggaatggta
     9001 ttttgcatac aaagacgaat tggaaaaagt atttcgtcaa gcggaggaac ggacgtccac
     9061 gtttccagct ccctttcagc aagaggggtt ggactatctg gcgcgtttta atccgttgcg
     9121 ggaagacagc acgcgtaatt acatatgcta tttgcttcca ttttggctgc aagaactcac
     9181 cggactcccc cccaaaacat gccgcaagct gtcacttggc aacgtgttcg tcatggccca
     9241 ctatttaatt caagatgatg tgatggacac agcagcagac aaccgtaaaa cgcaacttgc
     9301 cttaagccag ctattctata ccgagtgtct aagcgtatat cgggaccttt ttccggcaac
     9361 ctctcctttt tggtcatatg ctcgaacgta tgttgatgaa tgggccgtta gtgtgatatc
     9421 cgaaggaaca gaggactatt ttcaaggaga aagaaataag gtcgcgctga aagcaagtcc
     9481 attaaaaatg gccggaacgg gtgctttact gctcgcaggc cgtgctgatc tgatccagac
     9541 tattacaaat atgacggact tggcgctact cgtgcttcaa atgtcggatg attgggcgga
     9601 ttggtcagaa gatttggtcg aacatagcta taactgtctt ttgtcccata tcagtgccga
     9661 gcagaagaca gcttactgtg aaggattggg acctcaacag attcaggaag cgatttatgt
     9721 acgcggtgcg ctcgccagct atgtgaacat tgccgatcaa gcagtccaac agttagagac
     9781 cctggagcct tctatccacg gcctacgtag ctttgcacat tctatcacag cagaactggg
     9841 cgaagtggcg gcggaaattg aaggcggacg ctcgcatttg agaagaggcg gacttgatta
     9901 ctggctctcc aaaaatatga aataatgcta gatttttctg agtctttcgt ggtatactga
     9961 ctaggtaaat ataaccaatt gaatgagagg gtgatttttg atggctactg aagttcttca
    10021 aacacaagtc attcaaaaag cttgggagga tgccagtttt agagaaaagc tgatgacaga
    10081 tcccaaatct gcaattcgtg atgtgttagg agtcgtgatc cccgatcata tccaaatcaa
    10141 aacgttagag gaaacacctg atcagtttta tctggtaatc cccccagacc cctccggcgt
    10201 gctcgctgca tcccagaaac ctcgctcgat gtggtaaatt agttgttaat gcttatttaa
    10261 tctatattcc ttaatctcat gtgggtgggc tcagcaagct tccctccgtt ttctccgaat
    10321 gcaaaaaagc cggatattat ccggctacgg ggaagcggat ggtcgcttct gttcccaccc
    10381 cttttgcact tgtaaaagtt attttgccat tcatcgtttc aataatccga aaagtcacca
    10441 tcatccccaa acccgtgccc tttgtcttat tcgagaaata aggctcacct agtctggata
    10501 aagtctgagc atccatccct tcaccattat cccgaatatg aatgaccgct tctccgttat
    10561 ccacataagc ccatatatga atatgaccct ggtctcgcag cgcttcaata ctgtttttga
    10621 tgatattgat gaacgcctgc ttgaacttgg aggaattccc acgtactttg atttcctggg
    10681 gaatatccag cgaaattttt ccaccttgca aattagccat tggactgatg attccctcaa
    10741 tatgtttgaa ttcgtccaat atggtcaacg ttttggtttg gtcaaactct ggcttggcaa
    10801 aagtcagaaa atctgtaata atcgcggaag ctcgatccag ctcctccaga gcgatatgta
    10861 gatagtcttt atttttacca tcctcctgct tgctcatcaa ctgaagaaat ccacgtgtaa
    10921 cctgaagggg attacgtacc tcatgagcta cagatgcagc caaatcgcta ataatctcca
    10981 ttttctccga acgttgaagc tcattattga acatctccag ttctctggaa taccgaacca
    11041 cctgcttgtg cttttctgcc agccttctgc ccaaaatcgc gatcaacgcc agtacaaaac
    11101 cgaacacgcc ccatttccac aaaaacatat tgtagtgtcc gtccagaata aagaaccagc
    11161 tcagttcgcc gatagagatg actgcaaaaa atgcaaagcc tgtcgataaa atgatcgctt
    11221 cgtgatcacc cttaagtgcc atgcggaccg aagcaaatac cagcagtatc attaaggcga
    11281 cgagtaatat acccaggatc actacactaa aaaaataata tatatcgttc aaccgctcct
    11341 gtgctcctaa attcacaatc atcatggtaa agcagaacaa agagtaggcg gttaacaact
    11401 ttctgaattt gcgaatcagt ataatcgaat tgatattttg ctcaaaaaag taggctaatg
    11461 aaggtagcag aataaatagt gccacatcaa aaagttgtaa gtacagcttt ccatagccgc
    11521 gatagaatgt atacaagaat ggtgaatacg ttacgatcat cagaccaata gacaatacaa
    11581 tcgcacttag ggacagccac atggccatac tcggacggaa caggaaaaat gagcagatca
    11641 gtagtaccag ggcgataaag ataaacgtac tgcccagtac aatatctaaa acatccattc
    11701 tgaccaaggt ccccaacaaa tcacgataat caccggtcat cacattgccg ataatgccca
    11761 gtctattctt actgctttcc gtccatatgt ataatgtttt accgctgtct tccggcttca
    11821 gcggaatcag aatacgatta ttctcataat tgtacccacg gtaggattcg taaaaattgg
    11881 tcccatcttt atacagcgta atatgcctgc cataaatatt ttcaaaaagt accgctggcg
    11941 tttcatcatt tagcgaaggt aacttcatac gaatccaagc agatccttta ttaccgggct
    12001 gcctaagcag ttgtgtatca tcttcaatat gcatccagac cttgctggga tcctttacct
    12061 catctaaaga gccatcctcg tttaccgctc cccatctcat atcccaggag ggtattttat
    12121 aatccctttc cggggtcatt ttggccgcat aggtggagtg gcccagcgac aacagtatca
    12181 caatgaccgc tagcagggcg gcgacagctt tgggcacatg cctcatatta agcacctcaa
    12241 agttacatag taggatttac aagtttgtat acgttttaac attttttacg tcttgaaatt
    12301 atattattct atacgatgat gtgcatacct tcttcataag aagggtatca tgttcttttt
    12361 actcattttt tgtaaaatct tcatattgat taatgatcat ttcctgttcg cgccgctcct
    12421 tctgctctct aagccccaac catggttcag aatcttcatc ttcatagatc gtccaaatat
    12481 cggaaaataa gtaatcgcgt atttctacta tttttccagc ctgtccgcca tctgtccagt
    12541 ataagccttc cgggcgccga atgagggtgc gggaaaatcc cggggtagat gccttttgac
    12601 ctactcggat acgactaatc atcggaccaa acatgtacca ttccaattca tatccctccc
    12661 tatcttcttt atcatatcac agcagttacc aaaaaaacgc taattgagaa tgggcatatc
    12721 cctattcgca tgattttaac ttcctacaga cacactaact caaggtttag ccgttcttct
    12781 gtttgggtaa ggtcggaata agcaacaaaa agtaaaggag ctgagtaaca tggccaatcg
    12841 tgatgatcga actactgagc tacatgacaa tgattttgag ccttctctgc aaaatgcaga
    12901 aaccaactgg gagaatctga cggaagggcc agatactcct ctggaggacg tcccagatgc
    12961 cgatgaactg acaccgaaca gtcctgttga tccttctgct cctgccgaat tcctgcatgg
    13021 taccgatttg ttgaatggta ccgatgggga tgaagaagag caactggaca gcgacgatat
    13081 gctggattaa cattaaccac ttcattttat caggtgaaag aaaacggtta ccaattctgg
    13141 tatgcgggta atgaagtgta taacagaaag gagttgactg atctcctatg tataaagatc
    13201 cgatgtctca ggccgatatg gagtataagc gctacaaaac cttgaatcct gtggaagcag
    13261 acgaacgtag gaccgcggac aagacaatta cggacgatat ttcggccgaa gataacccac
    13321 gaggagtcgc atctgcgaag cccgaaccca gggatcaagg aaaatgaaag gaccgatagg
    13381 gaaatgcaaa aaaggtgcaa cctaagccac gcagatgata cgtggcttga gtgcaccctt
    13441 tttgtacttc atatgtttac aatggcagca atactactgt cgatttggct tccaatccct
    13501 ctaccatttc gttccaggca gcaggcttgt tcggcaatac tgtatagtaa cgacgcagga
    13561 aagctgccac caattcggcg ctcacttctt ccacgctatc atcctcaggc ataaagccta
    13621 aattcagccc ttctactgct actccatcgt tattccagga cggatgtaca tagtccaggt
    13681 ccaatcgctt atagcccaga tgagatagca cctcacgtcg cacgtacggg tccattggct
    13741 tgacaccacc aaaggtatgc tcgttgccac ggtaagggtc atagatttca gcaaacatcc
    13801 cctgcaactg ctgtccactg gcctgagcaa gcgcgtgcaa gtcattctga cgtcgtgtcc
    13861 aaagaaaacg gccaatgccc agtcccggtt gtccgatgac cgtaaaatct gtcatagcta
    13921 cattaaagtc ctcataataa cgatactctg ttgcaccgac taccttatcg tcctgtaccg
    13981 caacaaagac acgaataccc gggtcttcca gtggttcctt ccacaggctg tactccagca
    14041 cttcctctgg tggaaatact tcctgcatta gctgatgcat gctcgcaaac aaggggtctt
    14101 caatatgagt aatgcgatga tattccatag gacacactcc tcttcaatta gtgatgggta
    14161 tgaaacggat ttcgccattc catgagggca gcataattac gcgattgttc atcatccaaa
    14221 taattcggca ggatgcagac aggcacccgt ccgcaacgaa gtagaaaagt taataccggg
    14281 tccttcagtt caccagacac tacggcatcc acatacgctt ctgcgctcaa ttggtcggca
    14341 tgatgctgat aaccaggcat acggcccgcg cccagcaaac gatccagtct ccgttcaatc
    14401 acaagatgat ataaggaaaa aatcagccat ttacccagac ccaatctgcg gtaagcagga
    14461 cgtaccgcta agtcaatcac atacagcgcc ttagcgtcct cacagtgtgt acgaatataa
    14521 ccgtcgtccg caacttcctc ccatgtatgc tgaggatgtt cggggttata atgcatcagc
    14581 aggctggtta ccgaacccgc cagttccccc tcaatttcca cacacagcgc tccatctgca
    14641 aaatgctcta tctggctggc aatctgctcc cggctccata acagctcctg cggataaggt
    14701 ggcgggaagc tctccagctg aatacgcagc aatccctcat aatcggctgt agaataatta
    14761 cgaatcaccg cccgaagcgg tcgatcgccg tcaaagatga accattcttt gcgatacatg
    14821 gcttatttcc tttcattagc tccagtctgt gtacaaatct gttctacgat cacgccaggt
    14881 tgtcaccgag ccacgctcgc gtacatcgta caacagctgc aaatcgagat ctgctgtcac
    14941 aatcatatcg ttgttcagtt caccctccac cataatgccg cgtggcggaa aaggaatgtc
    15001 attgggtgta atgactgcgg cttgcccata attggcacgc ataaaatcaa ccgtaggcaa
    15061 agagccgaca gtccccgtcg aaacgacata cacctgattt tcaaccgctc tggcgtggct
    15121 tgtataccgt acccggtaaa atccgtgacg atcgtccgta caggaagggc agaaaataat
    15181 atctgctccc ttcgccttcg ccatgcgaac gatttcggga aactcaatat catagcaggt
    15241 cagcatcgct atggtgccct tggacgtctc aaacacattt agtccctcac cgggagccat
    15301 attccattca tgcacctcag tcggtgtaat gtgaattttg tcctgggtgg ccacgcgtcc
    15361 gtccgggtaa aacaaatgtg ccgtattata taaacgttcg tttcgcctaa ttacatgagt
    15421 gccgccaata atatgcatcc cggttcgacg ggcgaacgaa gtgaataatt caaggtaccg
    15481 gtcggtaaaa tccggcaggt cgttgatcgt caaagctttg cctttactct caccgatcga
    15541 cataagctgg gtcgtaaaaa actcgggaaa caggacaaat tccgcgccaa attcctcggc
    15601 tgttttaata taatgctccg attgcagggc aaattgctcg aatgagtcaa tcgtatgcag
    15661 atgatattga accgccgata ctctgatttt gctcataatt cctcctcgga catcacgtct
    15721 tttagattgc aagggggtcc cgttgctgtt cacattataa ccgattcaaa acggtgcgaa
    15781 aactgaacct gataatcagg gcttgccttc tgcacctact ttgtttaaaa taaggtcaaa
    15841 tcttttgaat accatgaaca aagacagcga cggagacaag taaacgtcta acggattccc
    15901 acagaaaggt acgaattgct gagagcgtac cgcaatcccg cgttgaaatt cactcccgag
    15961 tcgagccttg aaccgacaga aggattcatt cctttgtccg cagtagaggt ttccggaagc
    16021 ccccgttacg ggcatcaagc tcagaagtta ctgccgtcga ctgaacgacg ttgacgattc
    16081 gtatgtatac ttctgtaatt agggtggtac cacggcattc gtcccttgcg acgagtgcct
    16141 ttttgtgtta ttttctgcaa aaaagtctat gggctgacag aaaaaacaaa tttaaattcg
    16201 ggaagggtgt actgtatgtc tacaaatgaa aattctttgg agctgctgcg tgaacagctc
    16261 gatgctacaa atttgcaatt gctggagctg ctgtcccaac gcgctgaact ggcgggacaa
    16321 cttggaaaat tgaaggaagc tcaaggggta cctgactttg atccggtacg tgagcaacaa
    16381 atgctggaca agctgatcgc ggctaaccgt gggccttttg acgatgctac gattcgccag
    16441 ctgttcaaaa atattttcaa ggcttctttg aactatcaaa aagaagaaca caaaaaacat
    16501 ctgatcgtca gccgcaaaaa tcaaccggat agcactgtta ttaaggttaa agatacgctg
    16561 gtgggcggca aagcctccat catggtcgca ggtccctgct cggtagaaag ctaccagcaa
    16621 actcgtgaag taggtgcggc tctcaaggaa gccggtgtgc cgattcttcg tggtggcgcg
    16681 ttcaaaccac gtacgtctcc gtacgatttc caaggactgg gcgtggaagg actgcaaatt
    16741 ctcaaacgtg taggcgacga gttcgggctg gctacaatca gtgaaatcgt cgatccaaga
    16801 catttggagg aagcgatcca atacatcgac attattcaaa ttggtgcgcg caacatgcac
    16861 aactttgagt tgctcaaagc tgcgggtgaa accagaactc cggttctgct caaacgcgga
    16921 ctggctgcca ctatggaaga gttccttcat gctgctgaat acatcgtttc ccgtggtaac
    16981 acgcaagtca tgctgattga acgcggtatc cgtacgtacg aaaaatggac gcgtaacacg
    17041 ctggatattt ctgctgttcc gattttgaaa aaggaaagcc atctgcctgt attggtggac
    17101 gtgactcact ccacaggacg taaggacatc ctggcccctt gcgccaaagc tgccttggct
    17161 gctggagccg acggtatcat ggtggaagtc catccgaacc cagcagtcgc tttgtccgat
    17221 gctcagcaac agctgaacat tcctgagttc cacaacttcc tgtctgaagt caaagaatcc
    17281 ggtttattca aagcgtaaaa ctaattttat gccgggattc ataaaccgct ttcattttct
    17341 cggattatgt tgtagaatct aaacaggatt gtgactgatc atgcaggcaa aacctagata
    17401 tatgtatgcg ccatttctat ggatgcatat atgtatttag gtttttttta tatcttgaat
    17461 catgaataaa aaggatgctc gcatggttat aatcctaaaa catcctggaa acgttcagag
    17521 aggggaacag aaatgagaga aagaaaaggg ttaagcattt ttttattagc catgatatgt
    17581 attttgatca tcagtggttg cagcggcgga aaagctcctg ctgttgcaaa ggatgaaagc
    17641 gctgctccag caaaagaaca agtggacaat aaagtagaaa ctaaagcgac gaaggccaga
    17701 acggttatta caaccgatgg agaagtcgat gatatgaatt cggttattcg cttcctcctc
    17761 tattctaatg aaatggactt gtctggtatc gtattgacca gttccgtgta tcattatgca
    17821 ggtgatgaaa aggccggcat caagccattt agatggactg gaactcaatg ggtaacggat
    17881 atgatcgatg cttatggaga aatttaccct aatctaacta aacaagccga aggatatcca
    17941 aagcctgaat atattaaaag cgttaccaag ataggcaata tttcatacaa aggtgagatg
    18001 gacaaagaaa cagaaggatc taatttcctt aaaaatctct tcctagatga tgacaaaaga
    18061 gatttatatg tacaaacctg gggtggcaca aatactacag ccaaagcttt aaaatctatt
    18121 gaggacgaat acaaaaatac agctcaatgg gctgatatcc aaaaaaaggt gagcgataag
    18181 ctcgttctat atatcatttt ggatcaggat gacagctaca ataagtacat cgcaaagaat
    18241 tggccagaca tcagaattat taatgatcaa tctaacttct ggcatttcgc ttatgcttgg
    18301 aaaatgcata cagaagaagt aaacagcaag ttgcacgggg aatggaactt caaaaatatt
    18361 aaagatggtc atgggaagtt gctcaatatg tatgccttga tgggcgatgg caatatcatc
    18421 aaaggcgagt tggatgaaga acaaagaggc agtgaagcct acttaaagaa aaatccacaa
    18481 tacgacaagt atgactttat ttctgaaggt gattctccat ccttcttcta tttaattgat
    18541 aacggattgc ggagtatgga aaacccatcc tatggtggct ggggaggtcg tttcggtgtc
    18601 gttaacgata aattatttag aaataccgtg ttagattatg atgtgcatac gaaaaaattc
    18661 gaagcagaat attctctgat gcgttggttt gatgatattc aaaatgactt tgctgctcgt
    18721 gcagattggg ctattgcatc cgactacaaa gatgccaacc ataatccaac gttgaccatt
    18781 aaagaaggat tagacctaac cgctagtcca ggggagaaaa taaccctgca tgcagaaggt
    18841 tcagatcccg acggtaatca attgacctat aaatggtgga gatattttga agcagacacg
    18901 tatgaggatt ctaaagtaaa accagcacaa gttaaacctg aattgctggg ggaaatgcag
    18961 cttgggcttc atcgagaagt agctaaaggc gagaaagtaa acacgattga cttgcaaggt
    19021 agtgatacga atgcagttag tttcacagtt cctgcagatg ctaagtcagg gaatacgctt
    19081 catatcattg cagaagtaca ggacaatgga aaacatcctt taaagcatta tcaacgtgtg
    19141 attgtaaccg taaaataatt gaacacaaca tccaataaaa ttaggcccat ggaataacac
    19201 tccatgggcc tgtttatttt tgcacatcgg acctcagaca atctctatac acgtttaatg
    19261 cttttttcag tcaaaggaac ataatatcct ttgccattcg gacccatagc aaatttattg
    19321 cgaagatgga ttagattagg gccgaatttc gcctctaatt gttcacggaa ctcatatagg
    19381 atttccatga tataaatatc atgaataatc acttctgtaa tcggcatcac cagacccgga
    19441 tgtaacgtcc atgcagcgcg gctgtcatca ccaagtgaaa gtatgccagc tacgacctcc
    19501 cggtcgtcta cgctaagtac aatccaccga ccaccaattt cagacgtaat ctcctcactc
    19561 atatcatggc ggtaaacatt agcgaaatca aaattaagct ccccatacgc tacaatgatc
    19621 acttcaattc cttgttgagc gacttgctct aaggcatctc ggaacacctc ggcatcctct
    19681 ttccaaattt ccaataaaat tcggtgtttt gctcccttta ccccttcatt tatgcgattg
    19741 ataatggctt cataccccga aatattccat atattctctc tattttgaaa tgatgctgtg
    19801 tactgctcca aactctcttg cgccacattg aaaatctgct ctgctttgcg ttttctctgg
    19861 gcaatcaatt catgtggcgg gagcggcaca tacagaggcg tattttcttg actgaccatg
    19921 atatccccac ggttgaccat tccagacaaa acctcgtaaa ttttggatct cggtaccccg
    19981 gaattcaatg aaacggcgta tcccgaaagt ggagagcttt ccaataaggt cacataagcc
    20041 ttggcttcat attcactaaa attcaaatcc cgtagaattt ctaatatatt tggttttggt
    20101 ttcatgacgt cttctcctca attcgtgttc atccttacta tatcacttcc ccttgacaaa
    20161 aactgatata cacactatct ttttagtaac gtttttatag tagtcacttt agtagctact
    20221 atcatcattt cacaggg
//
