LOCUS       NZ_POVS01000013        20924 bp    DNA     linear   CON 15-SEP-2024
DEFINITION  Paenibacillus sp. F4 F4_contig_12, whole genome shotgun sequence.
ACCESSION   NZ_POVS01000013
VERSION     NZ_POVS01000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. F4
  ORGANISM  Paenibacillus sp. F4
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 427291)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Genome sequencing and comparative analysis of polymyxin-producing
            Paenibacillus strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 427291)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2018) Infectious Disease Research Center, Korea
            Research Institute of Bioscience and Biotechnology (KRIBB), 125
            Gwahak-ro, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-JAN-2018
            Assembly Method                   :: CLC Genomics Workbench v. 11.0
            Assembly Name                     :: F4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 524.4x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002894905.1-RS_2024_09_15
            Annotation Date                   :: 09/15/2024 04:37:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,419
            CDSs (total)                      :: 5,299
            Genes (coding)                    :: 5,203
            CDSs (with protein)               :: 5,203
            Genes (RNA)                       :: 120
            rRNAs                             :: 10, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 102
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 42 of 96
            Pseudo Genes (incomplete)         :: 67 of 96
            Pseudo Genes (internal stop)      :: 14 of 96
            Pseudo Genes (multiple problems)  :: 22 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:44:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 161197
            Orig. end                         :: 182121
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            POVS01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20924
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20924
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20924
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10924](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10924
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            1171..1941
                     /gene="spoIIIAF"
                     /locus_tag="C1T21_RS13910"
                     /old_locus_tag="C1T21_13910"
     CDS             1171..1941
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822294.1"
                     /locus_tag="C1T21_RS13910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13910"
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_103048682.1"
                     /transl_table=11
                     /translation="MTWLGGWLKELVLIVLLASFVDMILPSRSMERYVKLVLSLLILLT
                     LLSPVVRLLSSSPSEVLGRALDLQRQAETGKREPTLEEILAKGSQLKQQQEQSSMQWAG
                     KEVAKEMKGQLEQYTGLAIQSVQVTLAKIQQKESGLEAGTGVQSVVVKLAEQQPEKEKK
                     NTDVSPGADAKPIMVEPVTEKTVNIRVEPTHTKTSELNEGTREDDRNPDKTAEDGKPTD
                     TKAFGLITGLLSEKWGIDSKNVQVVSSQDGTHEW"
     gene            1958..2599
                     /gene="spoIIIAG"
                     /locus_tag="C1T21_RS13915"
                     /old_locus_tag="C1T21_13915"
     CDS             1958..2599
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427500.1"
                     /locus_tag="C1T21_RS13915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13915"
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_029517255.1"
                     /transl_table=11
                     /translation="MSKWLKKLEQWLGGGADGAKRFNSFRWLLILGLIGVAIMLFNSFV
                     NVKKVDPENVGREPPGVMKNEPTLETTTGEESSFAGIEKVFEDNMKQMLEQIVGVGTVD
                     VMVTVDSTEEVIVQRNVKDMQEENNETDANGGQRHTTQYTRDGEIVTYESSGGQHTPIV
                     TKKVKPQVRGVLVVAMGAENPTVKQLIVDAVQKGLNVPSYKISVVPRKQG"
     gene            2662..3486
                     /locus_tag="C1T21_RS13920"
                     /old_locus_tag="C1T21_13920"
     CDS             2662..3486
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427501.1"
                     /locus_tag="C1T21_RS13920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13920"
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_103048683.1"
                     /transl_table=11
                     /translation="MNNKRQTVWLVSMLSLMVVLSAYYLFTEDSSPANPPVADSEQVSK
                     VKQDAAQEATTKAEEQLNELKVNEVVTNGEVTDGASATSTKSDTASTTDPATENSKGDK
                     DTAAIPTTEPATSDQNTTATKTDATAQSDDKAASTAKTDQQVLDQVATDQAAQPTAAAV
                     IDNYLLERDVENQKKNDELTTAMNDSTPKKAAEAQKELHVLEDKQAKITGIEEELQQQF
                     ANAVVREEDADKYKVVVLSEKLDAKQAVTIVDKVMKELNVTQDKISVQYVTQ"
     gene            3625..4116
                     /gene="accB"
                     /locus_tag="C1T21_RS13925"
                     /old_locus_tag="C1T21_13925"
     CDS             3625..4116
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310822.1"
                     /locus_tag="C1T21_RS13925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13925"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_029517257.1"
                     /transl_table=11
                     /translation="MFKLSEIKELIKLVDETSVHELEIENEGTRLLIRKPGKSEIVTVQ
                     APVATPAYAVAPQAVIPNPQVQSDVGSTTAGEPREYASNLHKIVSPMVGTFYSSSSPDT
                     APYVSIGSKVGEKTTVCIIEAMKLMNELEAEVKGEIVEILAENGQLVEYGQPLFLVKPE
                     "
     gene            4178..5521
                     /gene="accC"
                     /locus_tag="C1T21_RS13930"
                     /old_locus_tag="C1T21_13930"
     CDS             4178..5521
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371779.1"
                     /locus_tag="C1T21_RS13930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13930"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_103048684.1"
                     /sec_met_domain="ATP-grasp (E-value: 8.3e-08, bitscore:
                     26.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 3.5e-08, bitscore: 27.9,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.2e-10,
                     bitscore: 34.5, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFQKILIANRGEIAVRIIRACREMNISTVAVYSEADKDSLHVRL
                     ADEAYCIGPTLSKDSYLNFTNLMSVATLTECDAIHPGYGFLAENADFAEICESCNITFI
                     GPSPEAINKMGDKAVAKQTMKDAGVPVIPGSDGLVEDLQDAISIARDIGYPVIIKATAG
                     GGGKGIRIAEDEDNLIQQITTAQQEAQKAFGNAGVYLEKYLTGMKHVEIQIIADKHGNV
                     AHLGERDCSVQRRRQKLLEEAPCPVLSQDVREEMGQAAVRAALAVQYSGAGTLEFLLGP
                     DNNFYFMEMNTRIQVEHPVTEMITGVDLIKEMISVAEGHPLSFTQEEVTINGWAIECRI
                     NAEDPDRNFMPAPGKIGFYLPPGGPGVRVDSAAYPGYSIPPYYDSMIAKLIVWAPTRQD
                     AIAKMKRALSEFAIEGIPTTISFHQRLLEHPTFIKGDFDIKFLEENEV"
     misc_feature    complement(4186..4195)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            5647..6060
                     /locus_tag="C1T21_RS13935"
                     /old_locus_tag="C1T21_13935"
     CDS             5647..6060
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007430927.1"
                     /locus_tag="C1T21_RS13935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13935"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_013310820.1"
                     /transl_table=11
                     /translation="MSTVPTEFERTEIGEIQIAPEVIEVIAGLATVEVPGVAGMSGGFA
                     GGFAELLGRKNLSKGVKVEVGQREAAVDVSVIIEYGNRLPEVAAAIQHNVKRSIENMTG
                     LNVVEVNVQIHDVQFKNAEKVEEPEVLGAGRVK"
     gene            6134..6673
                     /gene="amaP"
                     /locus_tag="C1T21_RS13940"
                     /old_locus_tag="C1T21_13940"
     CDS             6134..6673
                     /codon_start=1
                     /gene="amaP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282227.1"
                     /locus_tag="C1T21_RS13940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13940"
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="WP_013310819.1"
                     /transl_table=11
                     /translation="MAKVMDRLLLFLYSLSIGIISILAILLLSGAIPYVLSIEDERVVW
                     FTSLIIAGVLLLLSLRFFYISIRRNQTVQHSIDQRTEYGDIQISVDTIENLCLKAASRF
                     RGMQDLKARVRVLESGLDITIRAVVDGESSIPVLTSEVQKGVHDHVEEITGIPVSNVSV
                     YIANVSQSPSFKSRVE"
     gene            6689..6922
                     /locus_tag="C1T21_RS13945"
                     /old_locus_tag="C1T21_13945"
     CDS             6689..6922
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282226.1"
                     /locus_tag="C1T21_RS13945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13945"
                     /product="DUF2273 domain-containing protein"
                     /protein_id="WP_023989248.1"
                     /transl_table=11
                     /translation="MPWKEIWGSYKGRIMGITAGIFFGFIYLWAGFWNMLFFALMVFIG
                     YTLGRRSDSALGSFLPWKEWGDWLSQRWRPFK"
     gene            7058..7507
                     /gene="nusB"
                     /locus_tag="C1T21_RS13950"
                     /old_locus_tag="C1T21_13950"
     CDS             7058..7507
                     /GO_process="GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310817.1"
                     /locus_tag="C1T21_RS13950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13950"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_013310817.1"
                     /transl_table=11
                     /translation="MKRRLARELAVQSMYHMEMNEVDAAAAVDMLLQEAAEENEAEVVV
                     KNAAVLRAYVLEHVRGTWEHKEAIDGLLVDYLKGWQISRLSRVDRQILRLAAYEMIFRE
                     DVPAKVAVNEAIELSKHFGTEESGKFVNGVLGRVIQELEQLKARF"
     gene            7545..8402
                     /gene="folD"
                     /locus_tag="C1T21_RS13955"
                     /old_locus_tag="C1T21_13955"
     CDS             7545..8402
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345647.1"
                     /locus_tag="C1T21_RS13955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13955"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_103048685.1"
                     /transl_table=11
                     /translation="MSAPIIDGKQISQDIRASIQQEVIRLKEHRFQPGLAVVLVGEDPA
                     SQVYVKNKEKACHDLGYYSEVHRLAADTSQEALLELVDKLNHQSTIHGILVQLPLPKHI
                     HEKAVIDAIAVEKDVDGFHPVNVGNLVIGDDSLLPCTPAGVIELIKRAGVEIAGKHAVV
                     IGRSNIVGKPVSLLLQRENATVTMCHSRTANIGDLSRQADILVVAIGKANFIDASFVKP
                     GAVVIDVGMNRLENGKLAGDVDFESVKQVSGPITPVPGGVGPMTITMLMQNTLVAAKRS
                     HGLA"
     gene            8415..9779
                     /gene="xseA"
                     /locus_tag="C1T21_RS13960"
                     /old_locus_tag="C1T21_13960"
     CDS             8415..9779
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345648.1"
                     /locus_tag="C1T21_RS13960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13960"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_103048686.1"
                     /transl_table=11
                     /translation="MAEQRIYSIKDLNRYIRMKLESDQVLSDVWIRGEISNFTHHSSGH
                     MYFTLKDEGSRIRSIMFATHNQRLPFVPKEGTRVIARGNVSVYERDGQYQFYATQMQPD
                     GIGSLYLAYEQLKQKLDAEGLFDTARKRNLPAHPATIGVITSPTGAAVRDIITTLQRRY
                     PQAGIVLYPVLVQGKGAAPSIVKAIEAMNRMQEVQVMIVGRGGGSLEELWAFNEEAVAR
                     AIYASVIPVISAVGHQTDFTIADFVADLRAATPTAAAELAVPNQAELRDQLLQREQRLR
                     NALRQRLETSRERLARLQRSPVLLHPRRYMLQHAERMDMLQQRLIRAAGNRSRLNAEKN
                     ARMRQVLERFNPREQIRSARKQTDMAQRQLESAMRAITKTGRQQLHTGIRQLDALSPLK
                     VMARGYSLVYDEQEKRLIKSLKDVQPGDSIKIKVSDGQLDCQVWGMKEDAKHGGE"
     gene            9769..10029
                     /gene="xseB"
                     /locus_tag="C1T21_RS13965"
                     /old_locus_tag="C1T21_13965"
     CDS             9769..10029
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371773.1"
                     /locus_tag="C1T21_RS13965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13965"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_013310814.1"
                     /transl_table=11
                     /translation="MANETELNFEAAMAALEEIVGQLEHGDVPLEQAIDLFQRGMKLSQ
                     LCSQKLEQVERKIEMIVEEDGDLRKKPFGGGLDENGGEGLE"
     gene            10001..10924
                     /locus_tag="C1T21_RS13970"
                     /old_locus_tag="C1T21_13970"
     CDS             10001..10924
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007430919.1"
                     /locus_tag="C1T21_RS13970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13970"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_103048687.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.7e-58, bitscore:
                     192.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTAVKGLNRPSFKEYLTGTADAVSSALTEQFPADWNIPDVLRES
                     MNYSLTAGGKRLRPLLVIAAAEAFGGSREAALPVACAVEMVHTYSLIHDDLPAMDDDDY
                     RRGKLTNHKVYGEAVAVLAGDALLTHAFYSIVQAGRRHGVSSDSLLSIVEDLSEMSGAR
                     GMVGGQVADMSGEQGITGIEELEYIHLHKTADLIIFSLLAGGRIGGANKSQLEALRRFG
                     RDLGLAFQIQDDILDLIGDESKMGKKTQSDVEQEKVTYPYFIGMDASLRQVEELTASAK
                     KVITESGIPDSSRLLEIADYLMKRDH"
     gene            11032..12930
                     /gene="dxs"
                     /locus_tag="C1T21_RS13975"
                     /old_locus_tag="C1T21_13975"
     CDS             11032..12930
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345650.1"
                     /locus_tag="C1T21_RS13975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13975"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_039270954.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 8.1e-126,
                     bitscore: 413.4, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.8e-08, bitscore:
                     26.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLPHIKQPGDLKSLSVEELASLAEEIRSFLIEKLSVTGGHLASN
                     LGVVELTIALHYCYNSPKDKMIYDVGHQAYVHKILTGRMDRFDTLRQRDGLCGFVKRSE
                     SEHDVWEAGHSSTSLSAAMGMALARDLKGEDNKVIAMIGDGALTGGMAFEALNHIGHER
                     KNLMVILNDNEMSIAPNVGAMHNYLSKIRSDRHYLRAKDELEVLLKKIPAIGGKLAKSA
                     GRVKDSLKYMMVPGVLFEELGLTYLGPVDGHDLPKLIETFQQADNVTGPVLVHVVTTKG
                     KGYKPAEADSHKWHGISPYKIESGQVLKAVGNPMYTEIFGRTLIELAEQDERIVAVTPA
                     MPGGSGLVPFSKEFPSRMIDVGIAEQHAATMCAALAMEGMKPVFAVYSTFMQRAYDQIV
                     HDICRHNANVMFAIDRAGFVGADGETHHGVFDVAFLRHIPNLVLMMPKDENELRHMMKT
                     ALDYEDGPIAYRYPRVNVVGVPMDKELQAIPIGSWELLRKGEGFAVIASGPMLQVATEA
                     AEAMKREGLQVGVVNARFLKPLDEDMLRELARQHTKLIVLEEASEAGSLGSAVLEFYAK
                     AEIQEAQVRLMGIPDLFVEHGSIKEQRAEVGLTIEDVCLKLRKWAAEPAYGMGQSV"
     gene            13007..13858
                     /locus_tag="C1T21_RS13980"
                     /old_locus_tag="C1T21_13980"
     CDS             13007..13858
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310811.1"
                     /locus_tag="C1T21_RS13980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13980"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_023989243.1"
                     /transl_table=11
                     /translation="MSVPKERIDVLLVEQGFFESREKAKAAIMAGLVLADSERIEKAGM
                     KVPRASELKVKGSVHPYVSRGGLKLEKAIRQFELDMKGRTMLDIGSSTGGFTDCALQHG
                     AEYVYAIDVGYNQLDWSLRNDERVCVMEKTNFRYMTPADLNGSVPNFASIDVSFISLRI
                     ILPPLLALLHQPADIVALIKPQFEAGREKVGKSGVVRDPATHKEVLQTILMFAHELGLT
                     LQGLAYSPITGGEGNIEFLAHWRLDGLPAAESQLEKMDFRPLIERTVQEAGQTFNNGPS
                     RK"
     misc_feature    complement(13927..13940)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.89"
                     /tool="antismash"
     gene            14014..14490
                     /locus_tag="C1T21_RS13985"
                     /old_locus_tag="C1T21_13985"
     CDS             14014..14490
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282218.1"
                     /locus_tag="C1T21_RS13985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13985"
                     /product="hypothetical protein"
                     /protein_id="WP_103048688.1"
                     /transl_table=11
                     /translation="MDTRYDTVIIAVIGVILGIWALYSLRAWLKEPGPLVLKTIPINED
                     LDEGPATDLLEEAGYEVVGGKMKIPLAFKVNGHTVYSRLFIDYVAVRNGSTYMVKTSRR
                     KKPMEWSGPDLRDKLMPYLLLYPGCAGVLYVDTDERSIRLITLVEDLEEEEYEG"
     gene            14507..14956
                     /gene="ahrC"
                     /gene_synonym="argR"
                     /locus_tag="C1T21_RS13990"
                     /old_locus_tag="C1T21_13990"
     CDS             14507..14956
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0034618 - arginine binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="ahrC"
                     /gene_synonym="argR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282217.1"
                     /locus_tag="C1T21_RS13990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13990"
                     /product="transcriptional regulator AhrC/ArgR"
                     /protein_id="WP_013310809.1"
                     /transl_table=11
                     /translation="MKGQRHIKIREIISQHEIETQDDLVEALRKAGFQVTQATVSRDIK
                     ELLLIKVPMDDGRYKYSMPSDQRYNPAQKLKRTLVDNFLHIDYTTNLIVMKCLPGTANS
                     IAALLDNIEWSEIMGTISGDDTILIICRSEENSEAIVNRLMGYIS"
     gene            15015..16733
                     /gene="recN"
                     /locus_tag="C1T21_RS13995"
                     /old_locus_tag="C1T21_13995"
     CDS             15015..16733
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371767.1"
                     /locus_tag="C1T21_RS13995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_13995"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_103048689.1"
                     /transl_table=11
                     /translation="MLVTLSIRNLAVVEAVDVHFYKGFHVLSGETGAGKSIIIDALGLI
                     AGGRGSADLVRYGCDKAEMEALFELPVKHPVWNTLEEQGIKANAEEHLLIRRELTVQGK
                     SSSRINGQMVNLTMLREVGEQLVNIHGQHEHQSLLRADRHLALLDTFGDSVIGPVKTLY
                     RERYNAFVKAEKEVRELQSSSQKAYQLLDMYRFQLEEIAAAELKLGEDELLAEERVKLS
                     HSEKMMDGISGAYELLSGRGGLDTINNVLSRLNDVQSYDSKSLQPIAEQIQSAFYQLED
                     AAFQLRSYREDIEFNPGKLHEVEQRLNQITGLQRKYGDSIEQILEYYSRIEQETDLLEN
                     KDERLEQLIAKRDDLLSDLLEISEELTEAREICAEELAEQVEQELKDLQMERTSLKVRI
                     DPIEDPRGYEYKGLKVRPTKQGIDNAEFLISPNPGEPLRPLGKIASGGELSRIMLAMKS
                     IFARHDQIPVLIFDEVDTGVSGRAAQSIAEKLYRLSSVCQVFSITHLPQVACMADHQYL
                     IEKNVHDGRTMTQIEGLTEDGRVKELARMLGGVEITEKTLHHAQEMLNLAEGKKA"
     misc_feature    15062..15076
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     gene            16857..18017
                     /gene="spoIVB"
                     /locus_tag="C1T21_RS14000"
                     /old_locus_tag="C1T21_14000"
     CDS             16857..18017
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014599992.1"
                     /locus_tag="C1T21_RS14000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_14000"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_103048690.1"
                     /transl_table=11
                     /translation="MNFYSRIKLLGLLLVFLMCSLGNAQHVQAALPPQASLDLFGSKSM
                     RTTQESVVPDLKVYPGGQTIGVKVKSSGVLVVGHHIIQESNDRKVSPGETAGIRLGDRI
                     THMNGKPLNSLARVAEAVDEAGKNKKPLDITLCRGEQTISTKLTPAYDQDDKAWRLGLY
                     IRDSAAGVGTLTFYAPDQGVYGALGHVITDMNTQTPIVVGSGEIVQSNVTSIAKSQSGE
                     PGEKRAHFLKDHRVLGNIERNTNFGIFGKMSDEPQYGLYSTPIPVAFANEVKEGPAEIL
                     TVLEGQQIQRFQAEIVHISQQDKPATKGLVIRIVDPKLLDKTGGIVQGMSGSPIIQNGK
                     LIGAVTHVFVNDPKSGYGCFIEWMLRDAGIMQNNVSLKSSSNLKAS"
     misc_feature    18023..18038
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     misc_feature    18108..18123
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.78"
                     /tool="antismash"
     misc_feature    18175..18193
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.4"
                     /tool="antismash"
     misc_feature    complement(18179..18197)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.51"
                     /tool="antismash"
     gene            18234..19037
                     /gene="spo0A"
                     /locus_tag="C1T21_RS14005"
                     /old_locus_tag="C1T21_14005"
     CDS             18234..19037
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /GO_process="GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345656.1"
                     /locus_tag="C1T21_RS14005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_14005"
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_023989239.1"
                     /transl_table=11
                     /translation="MQKIEVLLADDNREFTNLLAEYISDQEDMEVTGIAYNGEEVLQRI
                     AESRNIPDVLILDIIMPHLDGLGVLERLREMNLTPQPKIIMLTAFGQENITQRAVQLGA
                     SYYILKPFDMEVLANRVRQLVGPQLVSSSPVTISSMRSNVVPMGKTKNLDASITAIIHE
                     IGVPAHIKGYQYLREAITMVYNNIEILGAITKTLYPAIAEKFKTTASRVERAIRHAIEV
                     AWTRGNIDSISHLFGYTINISKSKPTNSEFIAMVADKLRIENKVS"
     gene            19565..20314
                     /locus_tag="C1T21_RS14010"
                     /old_locus_tag="C1T21_14010"
     CDS             19565..20314
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371761.1"
                     /locus_tag="C1T21_RS14010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_14010"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_103048691.1"
                     /transl_table=11
                     /translation="MNSIEYKEFYDKVGKINGWDFSNVKCISKGVKWDFYNEVAKTCKK
                     SDILLDIGTGGGEAILSIAESALLLVGIDHSTGMIETATKNSAESDIANVRFLQMDADN
                     LNFPENFFNVISSRHSCFYAKEIAKVLAKGGIFLTQQVSENDKLNIKEAFGRGQAWGAK
                     KDSLKAKYITELSDAGFNDIQSFEFNANEYYQTPADLIFLLKHTPIIPNFGEKEIDFQI
                     LQQFIFANQTEIGIRTNSERFMVIARK"
ORIGIN
        1 tttggtgtgc ctcagctgcg gtcctctttg cagatacacc gacaaacgaa tggatcagac
       61 agcaggcgga gcaaatgccc aaagatgaag tagaacatta ttgggacggg ctcatgcagc
      121 aatacggcgg atttttcccg gatcagaaaa cgccttcctt catggacatg ctgcttccag
      181 gcggtgaagg gttcagcata aagggtgtat tgagcgctat agctgatttt ttcatccatg
      241 aaatccgagt aaatgccaag ttgctcgtca ccatcgtcat gctcagcatt atgagtatgg
      301 tgctggaaac gctgcaaagc gcttttgaaa gcaaacaggt cagcaaagtg gcctacgcta
      361 tcgtatacat ggtcattatc attctggcga ttaatagctt tagtgtagcg attggttatg
      421 ccaaagaagc gattgatagc atgattcact tcatgatggc aatgttgccc ctgttgttta
      481 ccatgttagc ctcgatgggt aacgtcgtaa cagtttcggt gacccacccg ctgattgtat
      541 ttatgatcaa cacggtcgga acagtcattc atacgctggt tttcccgctg cttttcttct
      601 cggctgtgct gtacttggtc aactcgttga cgggcaaata caaactgacc cagctagccg
      661 atctgttgcg gaacgctgga gtagcagtgc tgggagtgct gctgaccata tttctgggag
      721 tcatttcggt acaaggcttg acatcgtcgg ttactgacgg attaacgatc cgcacagcca
      781 aatatattac aggtagcttt gttccggtgg tcggcaaggc gttggcagat gcgacagata
      841 cagtcatttc ggcttcgctg ctcgttaaaa atgccattgg tctggtagga gtcattatta
      901 ttttgttcct gtgcgccttt cccgccctca agattctgac actggctctc atttataaag
      961 tgacagcagc gatcatgcag cctttgggtg atacgcctat cgtggaatgt ctggatgcaa
     1021 tcggcaagag catgatttat gttttcgcgg cgctggcggc agtgggatta atgtccttcc
     1081 ttgcgattac agtcatgctc gcagcaggca atatgacggt catgatgagg taaccaatgc
     1141 atgtaaacca acaaggggga ggggagtgac gtgacctggc tgggaggctg gcttaaggaa
     1201 ctggtgttaa tcgtgttgct ggcttctttt gtcgatatga tcttaccgag ccgatctatg
     1261 gaaaggtatg taaaactcgt tctcagcctg cttattctgc tgacgttgct gtctccggtc
     1321 gtgcgcttac tgagcagcag cccctccgag gttctagggc gagcattgga tcttcaacgt
     1381 caggctgaga caggcaagag ggaaccgaca ttggaggaga ttttagcaaa aggcagccag
     1441 ttgaagcaac agcaagaaca aagctccatg caatgggctg gcaaagaggt agctaaggaa
     1501 atgaaaggac agttggaaca gtatactggg ttagcaattc agtcggtcca ggttaccctt
     1561 gcaaagattc aacagaagga atcggggctg gaggcaggaa cgggtgtcca gtcggtagtg
     1621 gtcaaattgg cagagcagca gccagaaaaa gaaaagaaaa acacagacgt ctcgcctggt
     1681 gcagatgcca agccgataat ggtggagcct gtaaccgaaa agacagtgaa tattcgtgtg
     1741 gaaccgacac atacaaaaac ttcagaactt aatgaaggaa cacgagaaga tgatcgtaat
     1801 cctgataaaa ctgctgagga cggaaagcca acggatacga aagcttttgg cttaattaca
     1861 ggacttctaa gtgaaaaatg ggggatagac agcaaaaatg ttcaggtggt ttcttcgcag
     1921 gatggaacac atgaatggta acaggaggtg agtagaaatg agcaaatggc tgaaaaagct
     1981 ggagcaatgg ctgggtggag gggcggatgg ggcgaaaaga ttcaactcat ttcgttggct
     2041 gcttatactt ggccttatcg gtgtagcgat catgcttttt aattcattcg ttaatgtgaa
     2101 aaaggttgat ccagaaaacg taggccgtga gccgcctggc gtgatgaaaa atgagcctac
     2161 gttagagaca acaacaggtg aagaaagttc ctttgccggg atcgagaagg tttttgagga
     2221 caatatgaaa cagatgctgg agcagattgt tggcgtagga accgtcgatg tcatggttac
     2281 ggtagattcc accgaagaag ttatcgttca acgcaatgta aaggacatgc aggaagagaa
     2341 caacgagacg gacgctaatg gcggacaacg acacactact caatatacac gtgatggcga
     2401 gattgtcacc tatgagtcat caggtggcca gcacaccccg attgtgacaa aaaaagtaaa
     2461 accgcaggtg aggggagtgc ttgttgtggc tatgggggca gaaaacccta cagtgaagca
     2521 gctaattgtc gatgctgtac agaagggact aaatgtacct tcctacaaaa tttcagtcgt
     2581 accgcgcaag cagggataat ttggaattta ggaacaaata agtttatatt ttaaaccatt
     2641 tatgaatatg gaggacggaa catgaataat aaaagacaaa ccgtttggct ggtgtccatg
     2701 ctgagtttaa tggtcgtgct gtctgcgtat tatttgttta cagaggactc aagccctgca
     2761 aatccaccag tagccgatag tgagcaagtg agcaaggtta agcaggatgc cgcacaggaa
     2821 gcaacgacga aggcagagga acaattgaac gaactgaagg taaatgaagt agtgacgaat
     2881 ggagaagtaa ctgatggagc atcagcaact tccacaaagt cggatacggc ttctacaact
     2941 gacccagcaa cagaaaactc aaaaggcgat aaagatacgg cagctatccc tactactgaa
     3001 ccagcgacat ccgatcaaaa cacaactgcg actaagacgg acgcgacagc acaaagtgac
     3061 gacaaagcag cctctacagc caaaaccgac cagcaggtac tggatcaagt ggcaaccgat
     3121 caagctgctc aacctacagc agcagctgtg attgacaact atttgctgga acgggacgtg
     3181 gaaaatcaga agaaaaatga tgaattgact accgcaatga acgacagcac accaaagaaa
     3241 gctgcggagg ctcaaaagga attacatgta cttgaagata agcaggctaa aattactgga
     3301 attgaagaag agcttcagca gcagttcgcc aatgcggtcg tccgtgagga agatgctgat
     3361 aaatacaaag tagtggttct gagtgaaaaa ttggatgcta agcaagcggt aacaattgtc
     3421 gataaagtca tgaaggagct gaacgtaacg caggataaga tcagtgtcca gtatgttaca
     3481 caataagaca aaaaacgcga aaaagcccgg atttctgcat tattccgggc tctttctatt
     3541 tttaatgatt gtgatataat acataaagct gtttcaacaa tgttatcagc aaccggcaaa
     3601 atgctgaagg agtgattaat agagatgttt aaattaagcg agattaagga attgatcaag
     3661 ctggtggatg aaacgtctgt gcatgagctt gaaattgaaa atgaaggaac tcgcctgttg
     3721 atccggaaac cgggcaaaag cgagatcgtt acggtacagg ctcctgtggc aacacctgct
     3781 tatgcagtgg caccacaagc tgttattcca aatccacaag tacagtccga tgttggatct
     3841 acaactgctg gggaaccgag ggaatatgca agcaatctac ataagatcgt atctccgatg
     3901 gtaggcactt tctatagttc ttcatccccg gatacggctc cgtatgtgag tattggcagc
     3961 aaagtgggcg aaaaaacaac ggtatgtatc attgaagcga tgaagctgat gaatgagctg
     4021 gaagctgaag tgaagggcga aattgtggaa attttggccg aaaacggaca gttggtcgag
     4081 tatggccagc cattgttcct tgtgaaaccg gagtaaaaag cttgtttgaa ccctcttttg
     4141 agggttcggc aagactgctc ccagggagga taaagtcatg acatttcaaa aaatattgat
     4201 tgcgaatcgt ggagaaattg cggttcgtat cattcgcgct tgccgcgaaa tgaatatttc
     4261 gacagttgct gtatattcgg aagctgataa ggattcgtta catgtgcgtc tcgcagatga
     4321 ggcttactgt atcggaccga cgctatctaa ggacagctac cttaatttta cgaatctgat
     4381 gagcgttgct acattgactg aatgtgacgc cattcatcca gggtacggat ttttggcgga
     4441 aaacgcagac ttcgctgaaa tttgcgaatc gtgtaatatt acgtttattg gtccttctcc
     4501 tgaagccatt aacaaaatgg gagataaggc cgtagccaag cagaccatga aggatgccgg
     4561 agttccggtt attccgggtt cagacgggct ggttgaggat ttgcaggatg caatcagcat
     4621 cgcacgtgat atcggatatc cggtaattat caaggccaca gcaggtggcg gaggtaaagg
     4681 tattcgtatc gctgaggatg aggataacct tattcagcaa atcactaccg ctcagcagga
     4741 ggcgcaaaaa gcatttggca acgcgggtgt gtacctagaa aaatatttga ccggtatgaa
     4801 acatgtggaa atacagatca tagcggacaa gcatggtaat gttgcccatt tgggcgaacg
     4861 ggactgctct gtgcagcgtc gtcgtcagaa gttgttggag gaagcaccat gtcctgtact
     4921 ttcgcaggat gtccgtgaag aaatgggtca ggcagctgtt cgtgcagctt tggccgttca
     4981 atactctggt gcaggtactc tcgaattttt gctcggcccg gacaataatt tctatttcat
     5041 ggaaatgaat acacgtattc aggtagaaca tcccgtaaca gaaatgatta ctggtgtaga
     5101 cctgattaag gaaatgattt ctgtcgctga aggacatccg ctttccttta cgcaggaaga
     5161 agtcaccatc aatggttggg cgatagagtg ccgtattaac gctgaggatc cggatcgtaa
     5221 ttttatgcct gcaccgggta aaatcggatt ttatctgcct ccaggcggtc ctggagtacg
     5281 ggtagacagc gcagcatatc caggttatag cattcctcct tattatgact ctatgatcgc
     5341 caagctgatt gtgtgggcac ctacacggca agatgcaatt gccaaaatga agcgggcttt
     5401 gtctgagttt gctattgagg gcatacccac aacgatttct tttcatcagc gcttgctaga
     5461 gcatccgacc tttattaaag gcgattttga tattaaattt ttggaggaaa acgaagttta
     5521 atcggtatat ttcctcagtt tgtcataatg aacgccaaat gatatagtat ggataataag
     5581 tgagcatgtc tgctttgaaa tccaaagctg gaatgaaact tattttgacc gaaaggtgtt
     5641 gaaggtatga gcacagtgcc aaccgaattc gaacgtacag aaattgggga gattcaaatt
     5701 gccccagaag ttattgaagt cattgccgga ctggctaccg ttgaggtacc aggcgtagcg
     5761 ggaatgagtg gcggatttgc tggtgggttt gccgaactgc taggccgcaa aaatttatct
     5821 aaaggtgtaa aagtggaagt cggacagcgt gaagctgctg tagacgtctc cgtcattatt
     5881 gagtacggta accgtctgcc tgaggtggct gctgctattc agcataatgt taagcgttcg
     5941 attgagaaca tgacaggtct taacgttgtt gaagtgaacg tgcaaattca tgatgttcaa
     6001 ttcaaaaatg ccgaaaaagt agaagagccg gaagtgctgg gcgccggacg ggttaaatag
     6061 agcgatactt tgtacaaacc cccgaccctt atgggtcgag ggtttactct aatttaagga
     6121 ggctgtgcgt ttcgtggcta aagttatgga cagacttctg ctgttcttgt acagcttaag
     6181 tatcggaatt atttccattc tcgccatcct cctcctgagc ggggccattc cgtatgtttt
     6241 aagtattgag gatgagcgag tggtgtggtt taccagcctg attattgcag gggttctgtt
     6301 gttattgagt cttcgttttt tttatatctc tattcgacgg aaccaaaccg tacagcattc
     6361 tattgatcaa cgaacggaat atggtgacat tcagatttca gtggacacca ttgaaaatct
     6421 gtgcctcaaa gcagcctccc gatttcgcgg gatgcaggat ttgaaagcac gcgttcgcgt
     6481 gttggaatcg ggacttgata ttacgattcg ggcggttgta gacggggaaa gctccattcc
     6541 ggtgttaacc tccgaggtac aaaagggggt acacgatcat gtggaagaaa ttacaggaat
     6601 tcctgtgtcc aatgtgtcgg tgtacatcgc taatgtttct cagtcaccca gctttaagag
     6661 tcgtgtggaa tagaggtgat tttccctgat gccctggaaa gaaatatggg gaagttacaa
     6721 gggccggatc atggggatca cggctggtat ttttttcggt tttatttatt tgtgggcagg
     6781 cttttggaat atgttgttct ttgcattgat ggtgttcatc ggatatacgc taggaagacg
     6841 tagcgattca gcgcttggtt catttctccc ttggaaggaa tggggcgatt ggttgtcgca
     6901 gcgttggcgt ccttttaaat gaaccctgtg atacgtgttc tccaaaatag agctgtagct
     6961 tctttgcgcc caacgttttg gaggatgcgt tcacaggttt ttttgtggaa attggttaga
     7021 atgaaaaata gatataggca agcgtaggag gcagggcatg aaaagacgtc tggcgaggga
     7081 attagcggta cagagtatgt accatatgga aatgaatgaa gtggatgcgg cagcagccgt
     7141 ggacatgttg cttcaggaag ccgctgagga aaacgaagcg gaagttgtcg ttaaaaacgc
     7201 ggcagtatta agagcgtatg ttttagagca tgtgcggggt acgtgggagc acaaggaagc
     7261 cattgatggg ctgttggtgg attatcttaa aggctggcag atcagcagac tttcacgtgt
     7321 agatcgtcaa attttgagac ttgcggcata tgagatgatt ttccgtgaag atgttccagc
     7381 caaggtagct gttaatgaag cgattgagtt gtcgaagcac tttggtaccg aggaatccgg
     7441 taaatttgtt aatggtgtac tgggacgagt gattcaagaa ctggagcaat tgaaagcacg
     7501 tttttaagta gagactactg aatcaggttg gagagtggtt aaacatgtca gcaccgatca
     7561 ttgatggtaa acaaatctct caggatattc gcgcaagtat tcagcaagag gtcattcgtc
     7621 tgaaagagca ccgctttcaa ccgggactgg ctgttgtatt ggtaggcgaa gatcccgctt
     7681 cgcaggtgta tgttaaaaac aaggaaaagg cgtgccatga tctcggctat tactcagagg
     7741 ttcaccggtt ggcagcagat acttcgcagg aagcattact ggaactagtg gacaagctga
     7801 accatcaaag tactatccat gggattttgg ttcaactgcc gttgccaaag catattcatg
     7861 aaaaagctgt cattgacgcg attgcagtgg agaaggatgt ggatggattc catccggtga
     7921 acgtagggaa tttggtcatc ggtgacgata gtctattgcc ttgtactcct gctggagtca
     7981 ttgagttaat caagcgtgct ggagtggaga ttgctggtaa acatgcggta gttataggtc
     8041 gcagtaatat cgtaggcaag ccagtgtctt tattgttgca acgtgaaaat gctacggtta
     8101 cgatgtgcca ctcccgtaca gcgaatatcg gggatctaag tcgacaagcg gatatcttag
     8161 tcgttgcgat cggcaaagcc aactttattg atgcatcgtt cgtgaagccc ggagcggttg
     8221 tgatagatgt ggggatgaac cgtctggaga acggaaagct ggcgggggac gttgattttg
     8281 agagcgtgaa gcaagtgtct ggtccgatta cgcctgttcc cggcggagta ggcccgatga
     8341 cgattacgat gctgatgcaa aatacgcttg tagcggccaa gcggtcgcac ggtttggcat
     8401 aagggcagct gcctatggct gaacaacgta tttactctat aaaggacctg aatcgttata
     8461 tccggatgaa actggaatcg gatcaggtgc tgtctgatgt atggatacgc ggggaaattt
     8521 ctaattttac gcatcattcg agtggtcaca tgtactttac gctcaaggat gaggggagcc
     8581 gcatacgttc gattatgttt gcaacccata atcagcggct tcccttcgta ccgaaagaag
     8641 gtacgcgtgt tattgcccgg ggaaacgtat ccgtgtacga acgagatgga caatatcagt
     8701 tttatgcgac tcaaatgcag cctgatggta taggaagcct ttatttggct tacgaacagc
     8761 tcaagcaaaa gctggatgca gagggattgt ttgatactgc tcgtaagcgt aatctccctg
     8821 cccatccggc aaccattggc gtgattacgt caccgaccgg agcggctgtg cgtgatatta
     8881 ttacgacact tcaacggcga tacccgcagg ctggaattgt gttgtatcct gtgcttgtac
     8941 aaggaaaagg tgccgcaccc tcgattgtca aggcaattga agctatgaat cgtatgcaag
     9001 aggttcaggt gatgatcgtc ggacggggag gtggctcgtt ggaagaactg tgggcgttta
     9061 atgaggaagc ggttgcgcgc gccatttacg catcggtcat tccggttatt tcggcagttg
     9121 gacaccaaac ggattttacc attgccgatt ttgtggctga cttgcgtgca gcaacgccaa
     9181 ccgcagcagc tgagttggct gtgcctaatc aggcagagct acgggatcag ctgctccagc
     9241 gtgagcaacg cctgcgtaac gccctccggc agcggctgga aaccagccgc gaacgcttgg
     9301 cgaggcttca gcgttcacca gtcttgctgc acccacgccg ctatatgcta cagcatgcag
     9361 agcgaatgga catgctgcag cagcggctaa tccgcgcagc gggtaaccgt tcgcgcttaa
     9421 acgcagaaaa gaacgcacgt atgcgtcagg tactagagcg gtttaatccg cgtgaacaaa
     9481 ttcgttcggc acgtaagcag acggatatgg cgcaacgtca gctggagtct gcgatgcgtg
     9541 ctattacgaa aacgggacgg cagcagttgc acacgggaat tcgtcagctg gatgcgctga
     9601 gcccactcaa agtcatggcc cgaggctata gcttggtata cgatgagcag gagaaacggc
     9661 tgattaagtc gctcaaagac gtacagccgg gagattccat caagattaaa gtaagtgatg
     9721 ggcagttgga ctgccaagta tggggaatga aggaggacgc gaagcacggt ggcgaatgaa
     9781 acggaattga attttgaagc ggctatggcc gctcttgaag aaattgtcgg acaactggag
     9841 catggagacg ttcctctgga gcaagccatt gatttgttcc agcgggggat gaagctgtct
     9901 cagctttgca gtcaaaagct ggagcaggtc gaacgtaaaa ttgaaatgat cgtggaagag
     9961 gatggagatt tgcgcaagaa gccttttggc ggcggattag atgaaaacgg cggtgaaggg
    10021 cttgaataga ccgtcgttca aggaatattt aaccgggacg gcggatgcgg tttcgtctgc
    10081 gctgaccgag cagttcccgg ccgattggaa cattcccgat gttcttcgag aatctatgaa
    10141 ttattcactc accgcaggcg gaaaacggct gcggcctctg cttgtgatcg ctgctgctga
    10201 agcattcggt ggaagcaggg aagctgcgtt gccagtggca tgtgcggtag aaatggtaca
    10261 tacgtactct ctcattcatg acgacttgcc agccatggat gatgacgatt atcggcgagg
    10321 taagctgacg aatcataagg tatacggtga ggcggttgcc gtccttgcgg gtgatgctct
    10381 gttgacccat gccttttaca gcattgtgca agcaggacgg cgtcacggtg tttcatccga
    10441 ttcgctattg tccattgttg aggatttgtc cgaaatgagt ggcgcgcggg gcatggtagg
    10501 tggacaggtc gccgatatgt caggcgagca aggaataacg gggatcgagg aactggaata
    10561 tatccatctt cataaaactg ctgatttgat tattttctcg ctcttggcag gtggacggat
    10621 tggtggggcg aacaagagtc aattagaggc gcttcgccgc tttggacgag acttggggct
    10681 ggcttttcag atccaggacg atatactgga cctcataggc gatgagagca aaatgggtaa
    10741 gaaaacgcaa agtgatgttg aacaggagaa ggttacctat ccgtatttca ttggtatgga
    10801 cgcatctttg cggcaggtgg aggaactcac cgcatctgct aaaaaagtga taacagagag
    10861 cggtattccc gattcttctc gtttgctgga gatagccgat tacctgatga agcgtgatca
    10921 ttagttgcgt tagagctgtt ttgacttgtc tgcgtttaag cacagtcaaa aagtgtgata
    10981 taatacttgt taactttaca cacaaacttg aaggaaagcg gggagatatg cgtgctgctt
    11041 ccacacataa agcaaccagg cgatctgaaa tcactgtcgg ttgaggagtt ggcttctcta
    11101 gccgaggaaa tcaggagctt tttgattgag aagctgtccg tgactggggg gcatctggca
    11161 tcgaatctgg gagtggttga gctcacgatc gccctgcatt attgctataa cagtccgaag
    11221 gacaagatga tttatgacgt tgggcaccaa gcctacgtac acaaaatatt gacagggcga
    11281 atggaccgtt ttgatacact tcgtcagcgt gatggacttt gtggttttgt aaaaagaagt
    11341 gagagcgagc atgatgtttg ggaagccggt catagcagca cttctctgtc ggcggcaatg
    11401 ggaatggcct tggctcgaga tttgaagggc gaggacaata aagtcattgc aatgatcgga
    11461 gacggagcgt tgactggggg gatggccttc gaagcgttga atcatatcgg tcatgagcgc
    11521 aaaaatttaa tggtcattct gaatgacaac gaaatgtcca tagcacctaa tgtaggagcc
    11581 atgcataatt atttgagtaa aatccgctcg gaccgtcatt atttgcgagc aaaagatgag
    11641 ctggaagttt tgctgaaaaa aatacccgcg atcggcggta aacttgccaa atcggctggc
    11701 cgtgtcaagg acagtcttaa atatatgatg gtgcctggtg tactgtttga ggaactggga
    11761 cttacgtatc tcggtccagt ggacggacat gatttgccga agctaatcga aaccttccag
    11821 caggctgata atgtcactgg ccctgtattg gtgcatgtcg taaccaccaa gggcaagggc
    11881 tataaacctg cggaagcaga ttcacacaaa tggcatggaa tcagtcccta caaaattgaa
    11941 tcgggtcagg tactcaaagc tgtaggtaat ccgatgtata cggaaatttt cggtcgaacg
    12001 ttgattgagc tggctgagca ggatgagcgc atcgttgcgg tcacgcctgc tatgcctggt
    12061 ggatcaggac tggtaccgtt tagtaaagag tttcctagcc gtatgattga cgtcggcatt
    12121 gctgaacagc atgcagctac catgtgtgct gcgttggcaa tggaagggat gaagccggtg
    12181 tttgcggtgt attccacttt tatgcagcgt gcttatgacc agattgtaca tgatatctgt
    12241 cgtcataatg cgaacgtaat gttcgcgatt gaccgtgcag gttttgttgg ggctgacggg
    12301 gaaactcatc atggcgtgtt tgatgtggca ttcttgcgtc atatccccaa tcttgtgctt
    12361 atgatgccaa aggatgagaa cgagctacgt catatgatga aaacagcgct cgactatgaa
    12421 gatggtccaa ttgcttatcg ttacccgcgt gttaatgtgg ttggcgtgcc gatggataaa
    12481 gaattacagg ctattcccat cggcagttgg gagctcctgc gtaaaggcga gggatttgct
    12541 gtaatcgcat caggaccgat gctccaggtg gcgacagagg ctgcggaggc gatgaaacgg
    12601 gaaggtttgc aagtgggcgt cgtgaatgcc cgtttcctga agcctttgga cgaggatatg
    12661 ttgcgtgagc tggctcgtca gcatacgaag ctgatcgtat tggaagaagc ttctgaagca
    12721 ggaagcttgg gtagcgctgt actggaattt tacgctaaag ccgaaataca agaggcacag
    12781 gtgcgcctaa tggggattcc cgatctgttc gtggagcatg gctccatcaa agagcagcgt
    12841 gctgaagtag gtcttaccat tgaagatgta tgcttaaagc tgcgtaaatg ggctgctgag
    12901 ccggcatatg gcatgggaca atccgtatag ggtaacttga agtgaagacc atgacgttta
    12961 taaaaagtat gacaagagca gcctggctgc ctaaagggag attaacatgt ctgttccgaa
    13021 ggaacgcatt gatgtattac ttgtagaaca aggctttttt gaaagccgtg aaaaagctaa
    13081 agctgcgatt atggctggtc tagtgctggc ggacagcgaa cggattgaga aggcggggat
    13141 gaaggtacca cgtgccagtg agcttaaagt taagggttcg gtgcatccgt atgtaagccg
    13201 tggaggattg aagctggaga aggccatccg tcaatttgag ctggatatga agggcaggac
    13261 aatgctggat attggctcgt ccactggagg ttttacggat tgtgcgcttc agcatggagc
    13321 tgaatacgta tacgccattg atgtgggtta taatcagctc gattggtccc ttcgtaatga
    13381 tgaacgagta tgcgtaatgg agaaaacgaa tttcagatat atgacacccg cggatttgaa
    13441 tggttcagtg ccgaatttcg caagtattga cgtttcgttt atttcattac gaattatttt
    13501 gcccccgttg cttgccttgt tgcatcaacc tgctgatatt gtagctctca tcaagccgca
    13561 atttgaagct ggacgcgaaa aggtcggaaa atccggtgtg gtccgtgatc ctgctacgca
    13621 taaagaagta ctgcagacca ttctgatgtt tgcgcatgag cttggactta cgctgcaagg
    13681 tttggcttat tcgcctatta caggtggaga aggcaatatt gaatttttag cgcattggcg
    13741 tttggatggg ctgccagccg cagaatcgca gctggagaag atggatttca gaccactgat
    13801 tgaacgtacc gttcaggaag caggtcagac ttttaataat ggtccatcgc gtaagtaaca
    13861 ttcaggggtt ctccatgagt tctgtgaact caagggaacc tctttttggt gtgagggatt
    13921 gattatagaa ctcacgttcg cctataatga gatgtacaaa ggaaaaggga ttttacttct
    13981 tgtcctagaa tatgtccatg aggtgatcgg tccatggaca caagatatga tacggttatc
    14041 atcgctgtga tcggggtgat attagggata tgggctttat atagcctacg tgcctggttg
    14101 aaggagccag ggccgcttgt gctaaagacg ataccgatta acgaggactt ggacgaaggg
    14161 cctgccacag acctactcga agaagcagga tatgaagtag tgggcgggaa gatgaaaata
    14221 ccgcttgctt ttaaagtgaa tggacatacc gtgtatagcc gtttgtttat agactacgtg
    14281 gctgtacgaa acggttcgac atatatggtc aaaacgtcac gccgcaagaa accaatggag
    14341 tggagtggtc ctgatttaag ggacaagctc atgccgtatt tattgctcta tccgggttgc
    14401 gcgggtgtat tgtacgttga tacggacgag cgaagtattc gccttattac attagtggaa
    14461 gacctcgaag aagaggaata tgaaggttaa tccataggag gattatatga agggtcaacg
    14521 acatattaaa attagggaaa ttatttcaca acatgagatt gagacgcagg atgatctggt
    14581 tgaagcattg cgtaaggctg gttttcaggt cacgcaggcg accgtatcgc gtgatatcaa
    14641 ggagttgctg ctcatcaagg ttccaatgga cgatggcaga tataaatact cgatgccttc
    14701 agatcagcgt tacaatccgg cccagaaact gaaacgtacg ttggttgata actttttgca
    14761 tattgactac acaaccaatc tgattgtgat gaaatgcctg ccgggaacag ccaactcgat
    14821 tgctgcttta ttggacaata ttgaatggtc cgagattatg gggacgatta gcggggatga
    14881 taccattttg attatttgcc gatcggagga aaacagcgaa gctatcgtga atcgtcttat
    14941 gggctacatt tcctaattat aatggctacg catattaggc gttttaattt gtacatcata
    15001 gaggtgaaag aacgatgctg gtcactttgt ctatacggaa tttggcggtt gtagaggccg
    15061 ttgatgttca tttttataaa gggtttcatg tgttgagcgg ggaaacaggt gctggtaaat
    15121 ccattattat cgatgcgctt gggctgattg caggcggtag gggctctgct gatttagtgc
    15181 gttacggttg tgataaagca gagatggaag ccttatttga actgccggta aaacatccag
    15241 tttggaatac acttgaggaa caagggatta aggctaatgc ggaggagcat ttgctgattc
    15301 gtcgcgaact tacggttcag gggaaaagct cttcgcgaat taacggccag atggttaatt
    15361 taacgatgct gcgtgaggta ggtgagcaac tcgttaatat ccacgggcaa catgagcatc
    15421 aaagcctact acgtgcagat cgccatctgg cgctgctgga tacgttcggt gactcggtca
    15481 tcggtccggt caaaacgctt tatcgggagc gttacaatgc ttttgtcaaa gcggaaaaag
    15541 aagtaagaga actgcaaagc tcaagtcaaa aggcttatca gcttttggat atgtaccgat
    15601 ttcaattaga agagatcgct gcggcggagt tgaaattggg agaagatgaa ttattggcag
    15661 aggaacgggt caagctatcc catagtgaga aaatgatgga tgggatatca ggagcatacg
    15721 aactgctaag cggcagaggt ggtctggata cgatcaataa cgtgttgtcc agattaaacg
    15781 atgtccaaag ctatgacagc aaaagccttc agcccattgc ggagcagatt cagtctgctt
    15841 tttaccagtt ggaggacgca gcattccagt tacgttctta tcgtgaggat attgaattta
    15901 atccaggcaa gctgcatgaa gtggagcaac gtttgaatca aattaccgga ttacagcgaa
    15961 aatatggtga tagtatagag cagattttgg aatactatag ccgtattgag caggaaaccg
    16021 atctgctgga aaataaagat gagcggctgg agcagctcat tgcaaaacgg gatgatttgc
    16081 tttccgattt gcttgagatt tcggaagagc ttacagaagc acgtgaaatt tgtgctgaag
    16141 agcttgcaga gcaagtggag caggagttaa aagatctgca gatggaaaga acgtcactca
    16201 aggtgcgcat tgatccaatt gaagatccac gcggatatga gtataaaggt ctgaaggtaa
    16261 gacctaccaa gcagggcatt gataatgctg aatttcttat ttcccccaat ccaggtgagc
    16321 cattacgtcc acttggtaag atcgcttcag gcggtgagct atcacgtatc atgttggcga
    16381 tgaaaagtat ttttgcgcgt catgatcaaa ttccagtact catttttgac gaggtggata
    16441 ccggggtgag tggtcgtgca gctcaatcca ttgccgagaa gctatatcga ttatcttccg
    16501 tttgtcaggt cttttccatt actcatttgc cacaggtggc atgtatggca gatcatcagt
    16561 accttattga gaaaaatgtt catgatggac ggaccatgac tcaaattgag ggacttacgg
    16621 aggacgggcg tgtcaaggaa ttggcacgga tgctgggtgg cgtggaaatt accgaaaaaa
    16681 cattgcatca cgcacaggaa atgctgaatt tggcggaagg aaagaaagcc tgaaaagagc
    16741 ggctggcgta atgtttaaca gttataaaag cctgggggca aggttacctt ataggtacgc
    16801 aattggcgac cacctttact cgtcaagcga aagaagcaaa gggagcgtga cagccattga
    16861 atttttactc caggatcaaa ttgctcggtc ttttgcttgt ttttcttatg tgttctctcg
    16921 gtaacgctca gcatgtgcaa gctgcgctgc ctccacaagc ttctttggat ttgttcggct
    16981 ctaaaagcat gaggacaacc caagaaagtg tagttcccga tttaaaagta tacccgggag
    17041 ggcagacaat tggggtcaaa gtaaaatctt caggagtgct tgtcgttggt caccatatta
    17101 ttcaggaaag taatgatcgt aaggtgtcac ctggtgaaac agcggggatt cgcctagggg
    17161 atcggattac acacatgaac ggcaaaccac tcaatagcct ggcaagggtt gctgaggcag
    17221 tagacgaagc aggtaagaac aaaaaaccgc tcgacatcac gctttgtcga ggggagcaga
    17281 ccatttccac caagttaaca ccagcatatg atcaagatga taaagcgtgg cggcttgggt
    17341 tgtatattag ggactcggct gcaggtgtag gtacattaac gttttacgca cccgaccagg
    17401 gtgtatacgg ggccttgggc cacgtaatta ccgatatgaa tacccaaacc cccattgtcg
    17461 tggggagcgg agagattgtg cagtccaatg tgacgtcaat tgcgaaaagc caaagtgggg
    17521 aaccgggaga aaaacgcgct cattttctca aagatcatcg ggtattagga aatattgaac
    17581 gaaatacgaa tttcggaatt ttcgggaaaa tgtcagatga gcctcaatat ggattgtatt
    17641 cgactcctat tccagtggct tttgcgaatg aagtaaagga aggaccagca gaaattttga
    17701 ctgtactgga aggtcaacaa attcagcggt ttcaggcgga aattgtacac atttctcagc
    17761 aggacaaacc agcaaccaaa ggacttgtga ttcgcattgt agatccaaag ctgctggata
    17821 agaccggcgg aatcgtgcaa ggaatgagcg gtagtccgat catccaaaat ggtaagctta
    17881 tcggggctgt gacacatgta tttgtgaatg atcctaaatc aggttacggt tgttttattg
    17941 aatggatgct gcgtgatgca ggaatcatgc agaataacgt aagcttgaaa tcatcttcta
    18001 atcttaaggc gagctagtgg ccttaagatt tttttgtcga aaagcagggg aataactcat
    18061 aaatgcaaga taaagaatca attataatag aaactataaa aaaaataaat aaaaataatt
    18121 ttcgacagaa ggaattcata attcgatgtc gaaatcatat actccgacaa gaaatattta
    18181 tatactgtaa acagatatca caatggaata tcactcaatg aggaggaagt acattgcaaa
    18241 aaattgaggt attgttggct gatgacaacc gggaatttac gaatttgctt gctgaatata
    18301 tttccgatca ggaggatatg gaagttacag gaatcgccta taacggcgaa gaagtgctcc
    18361 aacgcatcgc agaatcccgc aacatacctg atgtacttat tttagatatt attatgcctc
    18421 atctggatgg tctcggtgta ttggagcgtt taagagaaat gaacctgact ccacagccga
    18481 aaatcattat gctgactgca ttcggtcaag aaaatattac acagagggcc gtacagctcg
    18541 gggcatctta ttatattttg aagccgtttg acatggaagt gctggcgaac cgtgttcgcc
    18601 aattagtggg gccgcagtta gttagcagca gtccggtgac catttcatcc atgcggtcca
    18661 acgttgtacc tatgggtaag acgaaaaacc tggatgccag tatcacggcc atcatacatg
    18721 aaattggtgt accagctcac atcaagggct atcaatattt acgcgaagcc attacgatgg
    18781 tgtacaataa tatcgaaatt ttgggagcca tcactaaaac attatatccg gcaatcgccg
    18841 aaaagttcaa aacgacggca tctcgcgtag aacgcgccat tcgtcatgct atcgaggtag
    18901 catggacccg tggaaatatc gacagcatct cacacctgtt cggttacacc attaatatca
    18961 gtaagtccaa accaaccaat tcagagttca tagcgatggt ggcagataag ctgagaattg
    19021 agaacaaggt gtcctgaaag ggtcagaatg attgacggag caacggattt ttgtgttttg
    19081 gcgtttgtca atgataattg cagggatggc tactaatctc caaaacagcc gcccagatta
    19141 ccgataaact tctgaatagt agacaactaa taccgccttt ttattgattc ttccaagaac
    19201 caataagggg cggtattttt tatgaacgat tttcaatttc aactggacaa tttaaagttt
    19261 tcttcaatta tcgtcatttc attgctatca gtcgtcgttc taccaaggga gagagttgga
    19321 attattattg aactattgct tgatcgacaa gctctataag aaatataatt aaaacaatct
    19381 ttcaaatgag gtgaatcgga tgtcattccg tattgttcga agtatttagt ttacgggctg
    19441 gaaaaaacgc gtaccagccg tcaagggggg gaggtctatc cttttgacta caaaaactaa
    19501 aattctgaat gatatcggtc tgctaacccg tagtttttat ccttaattgg aaggtggaag
    19561 aaaaatgaat tcaatagagt ataaagagtt ttatgataag gttggaaaaa tcaacgggtg
    19621 ggatttcagc aatgtgaaat gtatctccaa aggagtaaaa tgggacttct acaatgaagt
    19681 agcgaagaca tgcaagaagt cggacatatt gcttgacatc ggtactggcg gcggggaagc
    19741 aattttatca atagcagaat ctgcattact tctagttggg attgaccatt ctaccggaat
    19801 gattgaaaca gcaaccaaga attctgctga atcagacata gcaaatgttc gctttctcca
    19861 gatggatgct gataatctaa attttcctga gaacttcttt aatgtaatct cttctcgaca
    19921 ttcatgtttt tatgcaaaag aaatagcaaa ggtgttagca aagggtggaa tattcctgac
    19981 acagcaagta agcgaaaacg acaaattaaa tattaaagaa gcgtttggaa gaggacaggc
    20041 atggggtgct aagaaagact cgttaaaagc taaatatatt accgaattaa gtgatgccgg
    20101 ctttaacgat atacagtcat ttgaattcaa tgcaaatgaa tattatcaga ctcctgcaga
    20161 cttaatattt ctcttgaaac acacaccaat tattcctaac ttcggagaaa aagaaattga
    20221 ttttcaaata ctccaacaat tcatttttgc taatcaaacc gaaataggaa taaggacaaa
    20281 ttcagaacga tttatggtga ttgctaggaa gtaaaacata aaaggatacc cgtttttggg
    20341 tatccttttt ttaaaagttt gatggaatga gtgaataaag attttcagca tctccctcgc
    20401 taaatggcag aaccaatggg aattatgagt cataataccc ttcacactgt ttataaaata
    20461 aaactgaatc agttgcacta accatcacaa ggaaaaattt cccttttgta aacagttctg
    20521 aaattctctt tatatttgat ataaacaatg tgtcgtttct tgtcgatata gtatctaata
    20581 taaagagaac tgaggagcga atatatgaaa tttaacatcc gaacaaaatt gatattgggt
    20641 tttcttgcgg taataatcct gctgatcgtg attagtacaa catctatctc aaaaatgaaa
    20701 aatttaggtg gcacttcgat ggcaattgat agccattgga tgccaagtgt gaccatcctg
    20761 ggaacgctaa atggtgatat atctgatgta gagcggattt cattaaacat tattgtagaa
    20821 cgtgacccag aggaaatgga gaaggttcag gccgaatatg ataaggtttt aaaaaaggtt
    20881 gaggacggcc gaaaaacata cgaaaaatta attgctaccc ctaa
//
