LOCUS       NZ_POVS01000009        27007 bp    DNA     linear   CON 15-SEP-2024
DEFINITION  Paenibacillus sp. F4 F4_contig_8, whole genome shotgun sequence.
ACCESSION   NZ_POVS01000009
VERSION     NZ_POVS01000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. F4
  ORGANISM  Paenibacillus sp. F4
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 823678)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Genome sequencing and comparative analysis of polymyxin-producing
            Paenibacillus strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 823678)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2018) Infectious Disease Research Center, Korea
            Research Institute of Bioscience and Biotechnology (KRIBB), 125
            Gwahak-ro, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-JAN-2018
            Assembly Method                   :: CLC Genomics Workbench v. 11.0
            Assembly Name                     :: F4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 524.4x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002894905.1-RS_2024_09_15
            Annotation Date                   :: 09/15/2024 04:37:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,419
            CDSs (total)                      :: 5,299
            Genes (coding)                    :: 5,203
            CDSs (with protein)               :: 5,203
            Genes (RNA)                       :: 120
            rRNAs                             :: 10, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 102
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 42 of 96
            Pseudo Genes (incomplete)         :: 67 of 96
            Pseudo Genes (internal stop)      :: 14 of 96
            Pseudo Genes (multiple problems)  :: 22 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:44:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 750301
            Orig. end                         :: 777308
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            POVS01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27007
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="3"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..27007
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27007
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:17007]"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17007
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(11..2791)
                     /locus_tag="C1T21_RS10580"
                     /old_locus_tag="C1T21_10580"
     CDS             complement(11..2791)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369098.1"
                     /locus_tag="C1T21_RS10580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10580"
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="WP_103048198.1"
                     /transl_table=11
                     /translation="MKRIDKILEYIAESTKKISKEALFAGEGITAAEIADDQKMLRNNV
                     SKELNNLLRDDLILKIKGRPVRFLHKQIIEDTFRVRLKEKQIEVKSIKEVLLPDEQVDP
                     FHALIGFRGSMRNQVEQGKAAILYPPRGLHTLIVGQTGVGKTMFARLMYHYGKYMKRFS
                     EHAPFIVFNCADYFNNPHLLLSHIFGHVKGAFTGADHEKAGLVEKADGGILFLDEIHRL
                     PPEGQEMIFYFMDTHTYNKLGETDRKRDASVLLIGATTEDPGSSMLKTFIRRIPITINI
                     PSLQERAIEEQMLILKHLFANEANRVNKPIRIESEVVRALIGSVTYGNIGQLKSNIQLV
                     CAKGFLNSIHENKEEIGLDFKNLPGNIRDGLFNIDKTQYKMKEIGCISSGLYITPEGRK
                     ALDEEVVSELPFNLYKLIEDKIGMLKEEGLDDAYIHRFIATDVNIHIKSFYNRFYNTKG
                     SRERILKIVDKDILEFSEQIKEMAKKELNRIYSERFVYAFSLHLSAFFKRTREKKYGDA
                     RIYEPMNDHNEEYRLAQTIKSLIESKFGVHVPEAEITYMAILLKSVEEERQGSVGIIVA
                     AHGTSTASSIVGVVDSLLGSSNLCAVDMPLDVSPREILELIIDKVKSIDRGRGVLLLVD
                     MGSLLNLEETIMERVGINVKTIDMVSTPLTLEAVRKASVFDMGIEEIYQSLKDFRGYNN
                     SSAAVKVVHKAIVTVCSSGKGAAVKLKEFVEKIVCDLTDEEILVVPANVRELDKVVQDM
                     RSKRTILAVIGVKRPSEPEIPFIPLEKLIEASGEQTLRELLLNNKQIPAVDQSVVVREL
                     CEESLKEFMTYLNPHKVLGMVMRFVQELELGLEVKFDYATKVQISTHTAYALERMVIRD
                     GLVYQGEVEKLDQRIFEVVNRSCSIFVSGMNLILSDDEKYYICEMLSEVYNFIPQ"
     gene            complement(2841..3662)
                     /locus_tag="C1T21_RS10585"
                     /old_locus_tag="C1T21_10585"
     CDS             complement(2841..3662)
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179: hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309474.1"
                     /locus_tag="C1T21_RS10585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10585"
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="WP_103048199.1"
                     /transl_table=11
                     /translation="METYKIVCIDIDGTLLNSAHQITEATKETILQVINDKQIPVVLVS
                     ARMPKAIIPLQKHLGISEPLICYSGALVIDKHGNKLNTRYIDKQMTQRLLDSLAAYDLH
                     VSLYKDDEWYIEQLDAWALQERDITNIEPRIYSFSKLTNGWREETDGTSKILCMGDPEE
                     IRRVLQVLRPVYGEEVNLYLSKPTYLEIMSKKASKTAAIQILLKEYQLKQSDCLAMGDN
                     YNDIDMLAFAGLGIAMENAPLEVKAAANTVTLSNDEDGVAHALKNHILFPK"
     misc_feature    complement(3701..3714)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.68"
                     /tool="antismash"
     gene            3937..5319
                     /gene="rpoN"
                     /locus_tag="C1T21_RS10590"
                     /old_locus_tag="C1T21_10590"
     CDS             3937..5319
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpoN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007428384.1"
                     /locus_tag="C1T21_RS10590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10590"
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="WP_103048200.1"
                     /transl_table=11
                     /translation="MIRYGLQQEQGFKLVMTPELRQAITILQYSSADLISFLHEQANDN
                     PVIDLPEFNMSIGSIKEEAERFSQKDQGDLLEHYRGGEKYPSVQRANPVTFLDFVPNPN
                     DTLFEHLNRQLGLVCGLTNSQRMVARYLIGNLNEMGYLELDVPTVASLLDVPIAEIEDM
                     LLVIQSFDPPGIASYSLEECLLLQLQLAGMDDECIVRMVSNHLADLANNRIQKIADALE
                     IGRQEVIQMADRIRKLNPCPGAAFAHKEQQYIIADITVEKANGEYLVLINDISAPRVEI
                     NPFYRQMMQDLPNSETKRFIHEKMNTAKWLINSLKQRRLTLLRVAKAIVEKQQDFFEHG
                     VYFLKPITQKEIADKTGLHESTVSRAVSNKFIQTPRGLFELKFFFTSSLTSADGDAASS
                     ESAKKRIKNLIDDEDKQKPLSDQALTTLLGKEGLHLSRRTVAKYREELRYLSSAKRKKF
                     EV"
     gene            complement(5540..6508)
                     /locus_tag="C1T21_RS10595"
                     /old_locus_tag="C1T21_10595"
     CDS             complement(5540..6508)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820912.1"
                     /locus_tag="C1T21_RS10595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10595"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_103048201.1"
                     /transl_table=11
                     /translation="MPSIKDVASLAGVAVGTVSRVINNSGSVKPDTRRKVEEAIQELNY
                     FPNEVARNFKMRKSKMVALLLPSIWHPFFSELAYYIEDELDREGFKLMLCNSGGKPEKE
                     LYYLDMLRQNKVAGIVGITYNDIENSVSNDIPIVSIDRHFNKKITCVTSDNYEGGRLAL
                     RELVKVGAQKPAFMGSVTSVFSETMNRRKGFIHEAQTLGVDYVIYEKPDPIVDDDAYFN
                     EFLNEHRDVDGIFAITDMLAANYIERARRQGIRVPEDVKVIGYDGIQDHPYFHPILSTI
                     RQPVEEMARMTIRLLYKKIEGETLDQQVYRLPIVFKQGETT"
     misc_feature    complement(6990..7003)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.91"
                     /tool="antismash"
     gene            7023..7748
                     /locus_tag="C1T21_RS10600"
                     /old_locus_tag="C1T21_10600"
     CDS             7023..7748
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:1902495 - transmembrane transporter
                     complex [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820470.1"
                     /locus_tag="C1T21_RS10600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10600"
                     /product="AzlC family ABC transporter permease"
                     /protein_id="WP_103048202.1"
                     /transl_table=11
                     /translation="MSIASELSGTKPDSLSFLHGVKDCIPTLLGYVCIGFAAGIVGASS
                     GVSTMEIAFMSALVYAGASQFIMCSMLAAASPPSVIILTTFIVNARHLLLSASLAPYFS
                     KYSLWKNIGIGALLTDESFGVASDKLAKGGQVSDRWMNGLNITAYLAWIVSCVAGGVLG
                     NWISQPEAFGLDFALPAMFLALLISQLQSVQTSKLKHRLLLVLCMAVLMYLLAWWVPSH
                     IAVIVATMITATIGVLTDK"
     gene            7745..8068
                     /locus_tag="C1T21_RS10605"
                     /old_locus_tag="C1T21_10605"
     CDS             7745..8068
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331885.1"
                     /locus_tag="C1T21_RS10605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10605"
                     /product="AzlD domain-containing protein"
                     /protein_id="WP_103048203.1"
                     /transl_table=11
                     /translation="MSINPNVLYIIIGAMFVTAIPRIIPFVVLQRLALPKPVLQWLSYI
                     PICIFTALVMENLLVRTESSVTLNGQVLMAVLPTLVTALWSKNLLATVVVGIVSMALVR
                     LLW"
     gene            complement(8113..9846)
                     /locus_tag="C1T21_RS10610"
                     /old_locus_tag="C1T21_10610"
     CDS             complement(8113..9846)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309469.1"
                     /locus_tag="C1T21_RS10610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10610"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_258012419.1"
                     /transl_table=11
                     /translation="MILLTTRELINSVVAGASGGSFQPVFIAFGVLIGVNLLYDLINIG
                     ESFFRKMFQSRLSNQVNIKIIEKAQKMSLQSFEDADVQNMLQRAQGEADFRPFEIFTQI
                     LAIISSVVTLFSTGAILIAWRWWAFLFIFLIPCLSFYSFLRIGQREFNVHFQRAGRQRE
                     SWYLSFLVTRDNSFKEVKIFQLGDYLRKRYKTILEGFYREDKVLAVRRSYTSLVFQIVN
                     QGACAFIIFMAIQATYVGQILVGNLVSLIQGITLTQSTSQSIVQGILSLCQNNLYIKQL
                     FDFLDMPEEAKIQKTVQQLPLSTIHSIEFRNVSFRYPNTEENAISNVSFKLHQGEKLAI
                     VGRNGSGKSTIVKLLTHLYSDFEGEILINGYSIHELDKDIFREKIGVVFQDFVHYEMAV
                     RDNIGFGNVASRENDEAIWTAIDKAGITDLIVGLPDKMNTLLGKWFEDGQQLSGGQWQR
                     IAIARAFMRNADIYVLDEPSSFLDPHAEKEVFQKFDQLIYEKIGVFISHRLSSARMADT
                     IILMEEGRIVEAGSHERLMDIDGVYAEMFRLQASSYLSQRECDFEEEDLSPSLVRTTGG
                     S"
     gene            complement(10001..13255)
                     /locus_tag="C1T21_RS10615"
                     /old_locus_tag="C1T21_10615"
     CDS             complement(10001..13255)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820473.1"
                     /locus_tag="C1T21_RS10615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10615"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_103048205.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.1e-191,
                     bitscore: 633.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 4.9e-15,
                     bitscore: 51.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.2e-53, bitscore:
                     178.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRQLHYTDAQKLHNEVRDRDERWFSACDFFLIRAPLLPLDRYFQ
                     VFSDQDVDSQLTLEEITRRLKLISQEAVVQEAISLASPSLMQFLHYLNDGHALDDKGEL
                     QKYEKTLNSFYRYFIRMTTRTTPFGLFSGVGQGICGKTTDLDIGSYPKHLKRARPDMEW
                     IYKLIQKIEADPAIFNQLKVFLNKTVMIKGNRAKLPFRPKHGAAEADDSAEIFNSIRFT
                     DVVRMTFEAAEHPIRVMELKEILLKAFPDATLEIISDYLQQLVEQEFILSELRPPLMDH
                     SPFHYIFEKIRKLDISDPWVHILHEIDALLLQYNQCTIGEGEKVYRKLCDKMLDIISVK
                     TPVQVDVKLDKDVTLPKHVLDEVSLGAEVMCKLYASPKTDELDEYLNRFLEKYGVYQEV
                     PIHELFDEDWGLGIPEMYRSNEKKSMGMEAFKRNAVLFQWVSNAISNHEIELALTDEQL
                     EQLMISDNYDTSPESMEIYYSIFADSPEKVDSGDYSLLLGASAGSNRAGKTFGRFLDML
                     SEEFVQKFSEIYDHHRCFHPDALLSEMVFMPEQGKISNISLSKNLMAYEIVSGTTSSKD
                     EDHTLCIDDLVVGATHDRFYVKSRRLGKEIIPLQTHMLNYKLSPHIFRFLTDITNKEIG
                     TWSYFDWGPLEQSPFLPRLVYKKIIISAAQWKLSKASLNISESCESKEGEALFHVWRQQ
                     WNVPRYVYLTMGDNRLLLDLCNLFHIKELLHEVSKTREGQELLLTECLGNPFHTPVQGT
                     AGRYMGEFVFPLKKKKIKVKPSIPSSQNHIVSQNFIAHTPSSIHRGIFPGGEWLYLKLY
                     GVKERETDLVGLSLGHLLKQPGFKDWSQKFYFLRYVDPEHHIRLRFQGEPDKLWTAGLA
                     QLNQWAAELREEGLITNMVIDTYHPELERYGGQTLMELAEQVFDVDSQWVIAYMKGIRS
                     NAFNLDIEIAAVMNIIHYLSGFGLTIQEQVKWLEERIDCKPHMKAFRDVKKTLITAVES
                     NYEWIGQTDTNTQVAFLALVEKRQAMIQQYAQAIILAKNNHELTNHPDDILGSIIHMHL
                     NRLLGVNREREIKCMALAKHTVANLLHRKGVSYVTV"
     aSDomain        complement(12425..12709)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C1T21_RS10615_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.70E-16"
                     /identifier="RREFam001.1"
                     /label="C1T21_RS10615"
                     /locus_tag="C1T21_RS10615"
                     /protein_end="277"
                     /protein_start="182"
                     /score="51.6"
                     /tool="antismash"
                     /translation="VFLNKTVMIKGNRAKLPFRPKHGAAEADDSAEIFNSIRFTDVVRM
                     TFEAAEHPIRVMELKEILLKAFPDATLEIISDYLQQLVEQEFILSELRPP"
     gene            complement(13230..13907)
                     /locus_tag="C1T21_RS10620"
                     /old_locus_tag="C1T21_10620"
     CDS             complement(13230..13907)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820474.1"
                     /locus_tag="C1T21_RS10620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10620"
                     /product="response regulator transcription factor"
                     /protein_id="WP_103048206.1"
                     /transl_table=11
                     /translation="MKQKFMVISSFRKIKHFFETLNTPENIRIMFYDSLYQAIPEIDEQ
                     CIGVALNQDHVTLEDLSYWHSIKEKFTVPFIFLSYHSDDQRQLDLLKQLFSMASPEYGM
                     EREQQAISLSPNVIFDPAGKVIWKQGHEHTLTMMEFRLLMYLLTAKECASTIDHIIDRV
                     WGVDAFTTSNTVYVHIRKLREKIEDDPSHPKILVTCHGIGYKLNIFPKNLEVVSCEETT
                     ALY"
     gene            complement(13957..15219)
                     /locus_tag="C1T21_RS10625"
                     /old_locus_tag="C1T21_10625"
     CDS             complement(13957..15219)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820475.1"
                     /locus_tag="C1T21_RS10625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10625"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_103048207.1"
                     /sec_met_domain="LANC_like (E-value: 7.1e-60, bitscore:
                     198.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEDLQGRSVEISKYIAQKLIDLSYTEKIVNHANNLSPSRGNSPW
                     NPSSLADGIPGVLVLLSEWGYLEPDQNWAEHVHSQLRYLDANSLLLLPRISLYYGTTGV
                     AYGILLASNNRANYNKLISQLNKYIEVKWGDLPVIGTTTEFSRQMDIINGLLGVGRYTL
                     EVAEDKAMCDLSRQLLDTITHFIPEYIHLSSREDSASIHLGLAHGITGILALLVTALQK
                     KIKVEGLHEAIKHIADFLLIQIQEDQYGWYWPVNSQAPSMNKREKKVGMREIEGWCHGT
                     FGIGWTLFRAGIECSNEEWKKIAEKAMQSIFCLDDELLNALSPTFCHGLAGLLHIAHRF
                     YNLTDNIAALHFADQIALKLVNLYDEELPFGYQDLEGTTHVHNVGILQGATGIALSLLD
                     YGIGKEHPKYSGRWSELFLIS"
     gene            complement(15296..15448)
                     /locus_tag="C1T21_RS10630"
                     /old_locus_tag="C1T21_10630"
     CDS             complement(15296..15448)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820476.1"
                     /locus_tag="C1T21_RS10630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10630"
                     /product="FDLD family class I lanthipeptide"
                     /protein_id="WP_103048208.1"
                     /sec_met_domain="TIGR03731 (E-value: 1.3e-05, bitscore:
                     20.7, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNQFDLDLQVAKNEVAPKGVQPASGLICTPSCATGTLNCQVSLT
                     FCKTC"
     CDS_motif       complement(15377..15448)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKNQFDLDLQVAKNEVAPKGVQPA"
                     /locus_tag="C1T21_RS10630_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15296..15376)
                     /prepeptide="core"
                     /locus_tag="C1T21_RS10630_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="5.90"
                     /molecular_weight="2508.0"
                     /monoisotopic_mass="2506.2"
                     /core_sequence="SGLICTPSCATGTLNCQVSLTFCKTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNQFDLDLQVAKNEVAPKGVQPA"
                     /leader_location="[15376:15448](-)"
                     /alternative_weights="2526.0"
                     /alternative_weights="2544.0"
                     /alternative_weights="2562.0"
     gene            15646..17007
                     /locus_tag="C1T21_RS10635"
                     /old_locus_tag="C1T21_10635"
     CDS             15646..17007
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309464.1"
                     /locus_tag="C1T21_RS10635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10635"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_103048209.1"
                     /sec_met_domain="LANC_like (E-value: 9.9e-56, bitscore:
                     184.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDSFVIQQSDQVRARDISKKIALRLCEPESVYSAVHSEHNVSP
                     ETKYHPWGETSLSHGYPGNIHLLSQWRATDLSYDWNRAIHLNMAQIQSSLAINGLHDLS
                     LYSGWAGIAASVREASNYGEYYSNFSQQIHQWMMPLTEQWLQSNTEQLSLHEGMPMQSF
                     DTISGASGIGRYILINSTNPICTPLVEPILQFLTDLTHPIHIHNHYVPGWYSPQKFQFL
                     DRDKRNYPLGNFNCGMAHGIPGPLALLSVAYSSGIEVKGQYQAIETITEWLLKYKYEDE
                     YGSYWPHIVPFEAETGSLRFDLERAREAWCYGTPGITCSLFLAGKALHNVELQKSAVKA
                     CVGAISYEIAKREMDSSALCHGLAGLLTISWRMWRHSKEPAFLPLIQQLTNCLLDRFQM
                     DSPLGYLDPEPRSDGSLTWLTKAGMLEGVAGIAAALLSVSENKEIGWDYILMLS"
     gene            complement(17008..17742)
                     /locus_tag="C1T21_RS10640"
                     /old_locus_tag="C1T21_10640"
     CDS             complement(17008..17742)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370165.1"
                     /locus_tag="C1T21_RS10640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10640"
                     /product="ABC transporter permease"
                     /protein_id="WP_103048210.1"
                     /transl_table=11
                     /translation="MGSILRVETIKLQWIMLWILIILDAVINSLMGVLELNDLKQFFSP
                     SWLTLYTYSAQFHSMFFYPLYCGIIASLLCAYEHRDGGWKILLSSPYPRQQIYYAKYIL
                     LILILGLDQLIFIVGYFVSGNIAGAPGEIPWSVVLSTGLGGWLGIFPLAALQLMLSIKI
                     RNFGASLGMSICCVVPNIVITGFHSSIGAWFPFTIPYYIMMPQTATYAPRVEPYSLGLI
                     VIFTFLAYLYGGKKMFVNRDWL"
     gene            complement(17757..18464)
                     /locus_tag="C1T21_RS10645"
                     /old_locus_tag="C1T21_10645"
     CDS             complement(17757..18464)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370164.1"
                     /locus_tag="C1T21_RS10645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10645"
                     /product="ABC transporter permease"
                     /protein_id="WP_023987832.1"
                     /transl_table=11
                     /translation="MILRVIKAEGLKLKKICWWIPLIQGCVLTGMTAVEWYLYFRQGPG
                     GVYAGFAVMFMFLSFVMLLGGTLLASIMAGTEHDTQTWKQLMAMPVPRSYIYLSKIVWI
                     VILQLGTALITVAGMSLIWVLYTNEPIPWRIMLLQPINASLATLPVLAIQLWLSTLFTN
                     QAFPLAFGIFGSIASLFLARTSILWIKILPWSYPALSSPLMKEHMIWVIVALSAGVIFT
                     GLGTLQFTKHEFK"
     gene            complement(18461..19384)
                     /locus_tag="C1T21_RS10650"
                     /old_locus_tag="C1T21_10650"
     CDS             complement(18461..19384)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426675.1"
                     /locus_tag="C1T21_RS10650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10650"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_103048211.1"
                     /transl_table=11
                     /translation="MSEYVIHTQQLTRRFGKREFVKRINLQVPGQQIYGFLGPNGAGKT
                     TTIRMLLGLIKSTSGEIEIFGKKLKDQRMEILKDIGSLVESPAYYAHLSAYRNLEIVTT
                     MRGLPTRRIHEVLDLVRLSKDAYRPVKGYSLGMRQRLGIAMALIANPKLLILDEPTNGL
                     DPSGIQEIRELIMSLPGAYGMTVLVSSHLLSEIEQIATYVGIINQGEMIFQGTMKELTA
                     KSKPQLFIETPDPVLAAGALIQHGWTAGAESIEQNEVVTPIVDRQQSSEMIKVLVEHNH
                     PIYRVTEKKKTLEEIFLELTGKERSL"
     gene            complement(19529..20599)
                     /locus_tag="C1T21_RS10655"
                     /old_locus_tag="C1T21_10655"
     CDS             complement(19529..20599)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686784.1"
                     /locus_tag="C1T21_RS10655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10655"
                     /product="sensor histidine kinase KdpD"
                     /protein_id="WP_103048212.1"
                     /transl_table=11
                     /translation="MNSLVKMSFRFMKVTLCFVLAYVLCFVICTILYIFIKSIFGASQN
                     INIDLFWTGLGIVQSVVFIAAYGWYIGKPLVYVIKWIGNIATGEFQAPLSELELPEGKK
                     NQKNSYKPPYQLYKEVFEQMSILSAQLRSNEEERVEIEKRKQQWVAGVSHDLKTPLSYI
                     EGYAAMLTAQEYDWSDEERRSFSMSISEKVTEMKQLIQDLNASMQLKESPLPIQLEKED
                     IVEFLRSAVIDIANHPSAEQYEFSFTSMEAACIMSFDSKLLGRALQNFLINAIIHNPPG
                     THVSMEVNKANDKLLISIEDDGIGMNPNKFMQVSHSQGHGIPIAKSFIEAHNGTLHILP
                     GSKAGTRMEISLPLNI"
     gene            complement(20596..21318)
                     /locus_tag="C1T21_RS10660"
                     /old_locus_tag="C1T21_10660"
     CDS             complement(20596..21318)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686783.1"
                     /locus_tag="C1T21_RS10660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10660"
                     /product="response regulator transcription factor"
                     /protein_id="WP_103048213.1"
                     /transl_table=11
                     /translation="MEEIAVLIVDDEQGLRDMLTTVLKKEGFLQVKHAATGREALQVVM
                     ESHVDVIVLDVMLPDNDGFEVCRQMRLYTDAPILFLTARDTDLDKLMGFGIGGDDYITK
                     PFNPLEVVARMKARMKYRKVSTVAMKPTLRTLDFGYFRLELESGVLFVEDKQVECPARE
                     WLLLVFLCKHPNRIFSVRQLYEAIWSEAFLGDEKTVVIHISRLRKKIEPDPKHPQFLIN
                     VRGLGYKMMMSVKMEEQE"
     gene            21483..22649
                     /gene="yhbH"
                     /locus_tag="C1T21_RS10665"
                     /old_locus_tag="C1T21_10665"
     CDS             21483..22649
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yhbH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370159.1"
                     /locus_tag="C1T21_RS10665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10665"
                     /product="sporulation protein YhbH"
                     /protein_id="WP_023987828.1"
                     /transl_table=11
                     /translation="MPEPRQPYSFVVSREDWSLHRKGYQDQQRHQQKVKDVIKQNLPDL
                     ITEENIIMSDGQQIIKVPIRSLDEYRFIYNYQKQKHVGQGDGDSQVGDVIGRDPASQKP
                     GKGEKAGDQPGHDIMETEVSIEELEDMLFEEMELPNLQQKDKDQIEVESIVFNDIRKKG
                     MQANIDKKRTILENLRRNAREGKPGIHHISPDDLRYKTWEEKTIPQSNAVIIAMMDTSG
                     SMGSFEKYCARSFFFWMTRFLRRQYEKVEIVFLAHHTEAKEVTEEEFFTRGESGGTICS
                     SAYLKALEIIDKRYPPSSYNIYPFHFSDGDNLTSDNERCVKLIEELIKRSNMFGYGEVN
                     QYNRSSTLMSAYKNIKKDQFMYYVIKEKGEVYQALRTFFRKREGGSVG"
     gene            22646..24088
                     /locus_tag="C1T21_RS10670"
                     /old_locus_tag="C1T21_10670"
     CDS             22646..24088
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309457.1"
                     /locus_tag="C1T21_RS10670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10670"
                     /product="SpoVR family protein"
                     /protein_id="WP_103048214.1"
                     /transl_table=11
                     /translation="MSTDQKELEYAISEIMEIADGFGLDYYPMRYEICPADIVYTFGAY
                     GMPTRFSHWSFGKTFHKMKMQYDFGLSKIYELVINSNPCYAFLLEGNSLVQNKLIVAHV
                     LAHCDFFKHNARFSASNRNMVESMSATADRINSYEMEYGSKAVESFIDSVLAIQEHVDP
                     QIIKPRHLDKQRYMELKIREQKEPGKRQRPPGPYDDLWSLDTVKQHDPAETEGIKIRQF
                     PPEPEKDIVWFIQEFSEVLEDWQRDIMTMLRDEMLYFWPQMETKIMNEGWASYWHQRIV
                     RELDLTGEETVEFAMLNASVVQPSKQSLNPYYLGLKIFEDIEKRWDNPTREEQERQGRK
                     PGEGRAKMFEVREFDSDTSFIRNYMTKKLTEDLDLYVFEKRGPDWKITDKSWENIRDQL
                     VFSRVNGGSPYIVVEDGDYLHTGELKLKHQYEGIELDLKYMERTLPYVYQLWGRTVHLE
                     TLIEGKLALFSYDGKKHHRKFV"
     gene            24303..>24593
                     /locus_tag="C1T21_RS28315"
                     /pseudo=""
     CDS             24303..>24593
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012575.5"
                     /locus_tag="C1T21_RS28315"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNIHPSFREVRESDQQVFPIAWYAVGWSKELKNKPLKKRLLGKDI
                     VLYRDDHRQVHAIHAYCPH"
     gene            24945..25334
                     /locus_tag="C1T21_RS28320"
     CDS             24945..25334
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039236.4"
                     /locus_tag="C1T21_RS28320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_308411639.1"
                     /transl_table=11
                     /translation="MKNGNGLLQYTFPQQWILTPAKEGRSKFINFVTFTPIEQELTAIY
                     GLAGRNFAKFVPGMSHIFSRYSGKVLEEDRAVVESQHPRPIPEALRMEAHVPADGPQVR
                     FRNRWYDFLVNDEPRVRLNPETTSS"
     gene            complement(25321..26502)
                     /locus_tag="C1T21_RS10680"
                     /old_locus_tag="C1T21_10680"
     CDS             complement(25321..26502)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820485.1"
                     /locus_tag="C1T21_RS10680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_10680"
                     /product="PD40 domain-containing protein"
                     /protein_id="WP_103048215.1"
                     /transl_table=11
                     /translation="MIKKNIDSYGQKNGSSHREDSRTRVFRQKATGVLMIGLIAGGLLS
                     GCGMKSAGETNPAFGMKPGQQLTVIDTDAPQKQVTDELVVSSIDRLGDVYARSWLSDEE
                     LIVERKTQLWIHNVETDKERILTPGRKAPQLLAVVSPDQRHVFFTEGSISSKYDIQGYI
                     LELSSGKVTSIGKLDMTNEVSWSDENDLITGTPDGKIQLIGLDGKAEELSFQDPNRSEL
                     MSHVEKVGNAIFYTGSDKQGYPVLNRFTLNHPQAVTIAEGAMSFAVSPDGKSIAIEKRK
                     WNTSEPARMIILDEQGKEKGIVGQGTLMSRGSWSSDGSKLAFSIYDEDQQGMRGLYVFD
                     QSTGKTTPVTTDIQSYDSPTVWSPSARFLSMYQNISEGGKQLNQSYIVEFKRK"
ORIGIN
        1 tctttgacca ttactgtgga ataaagttat atacttcgct caacatttcg caaatataat
       61 atttttcgtc atcagaaagt ataagattca taccagaaac aaatatgctg catgaacggt
      121 ttaccacctc gaatatgcgc tggtcgagct tttccacttc cccctgataa acaagtccat
      181 cgcgaataac catgcgttcc agcgcataag ctgtgtgagt agaaatttgg acttttgttg
      241 cataatcaaa tttgacttcc aatccaagtt ccagctcttg cacaaatctc atcaccatgc
      301 ccagaacttt gtggggattc aaataagtca taaattcttt cagactttcc tcgcataact
      361 ccctgacgac tacactttga tccacagcag ggatctgttt gttattcagc agtagctctc
      421 tcaatgtctg ctcaccgctt gcttcaatca gcttttccaa gggaataaac gggatttccg
      481 gctcgcttgg ccgttttact ccaatcacgg caagaattgt tcgcttagac cgcatatcct
      541 ggaccacttt atccaactcc cttacgtttg ccgggacaac cagtatttcc tcatccgtca
      601 aatcgcagac aattttctcc acaaactctt tcaatttgac cgctgcacct ttgccggagg
      661 agcaaaccgt cacaattgcc ttatgaacta ctttcactgc ggcgctgcta ttgttatatc
      721 ccctgaaatc ctttagcgat tggtatatct cctctatccc catgtcaaaa acactggcct
      781 ttcggacagc ctccagcgtg agcggagttg aaaccatatc aatggtcttt acattgattc
      841 ccacacgttc cataatagtt tcttcaagat tgagcaaaga gcccatatca accagcagca
      901 acacgcctct accacggtca atgctcttta ctttatcgat aataagctcc aaaatttccc
      961 taggactgac atcgaggggc atatcaacag cgcaaagatt agaactgccc agcaagctgt
     1021 ctacgacgcc gacgatgctg ctcgctgtac tggtgccgtg tgctgccaca ataattccca
     1081 cactaccctg tcgttcctcc tcaacagatt tcagaagaat cgccatataa gttatttcgg
     1141 cctccggtac atgtacaccg aacttagatt cgatcaaact tttgatagtc tgggccagtc
     1201 tgtactcttc attatggtca ttcatcggtt catagattcg tgcatcaccg tattttttct
     1261 ctctggtgcg cttgaaaaag gcgcttaaat gaagactgaa agcatacacg aatctctcgc
     1321 tgtaaattcg gtttagttcc tttttggcca tttccttaat ctgctcggag aattcaagga
     1381 tgtctttgtc cacaattttc agaattcgtt ccctgctccc cttggtgtta taaaaacggt
     1441 tataaaagct tttaatatgg atattgacat ccgtagcaat aaatctgtgg atgtaggcgt
     1501 cgtctagccc ttcttccttc agcatgccaa tcttgtcttc aattaatttg taaaggttaa
     1561 acggcagctc ggaaacaacc tcttcatcca aagcttttct tccttctgga gtaatgtata
     1621 ggcccgagga aatacatccg atttccttca tcttatattg cgttttatca atattaaaca
     1681 aaccatctcg gatatttccc ggcaggtttt taaaatcaag tcctatttct tctttgtttt
     1741 catgtatgct gtttaaaaaa cctttcgcgc ataccagctg gatgttcgac tttaactggc
     1801 cgatattgcc gtaggtgacg ctgccgatca gtgctcttac tacctctgat tcaatcctaa
     1861 tcggcttgtt taccctattg gcctcgttag caaacaaatg cttcaaaatc agcatttgct
     1921 cctcaatagc acgttcctga agggaaggga tattgattgt gatgggtatg cgcctaatga
     1981 aggttttcag catggatgat ccgggatcct ccgtcgtagc tccaatcaat aatacactcg
     2041 catctctttt tcgatccgtt tcgcccaatt tgttataggt gtgagtatcc atgaaataga
     2101 aaatcatttc ctggccttcc gggggtaaac ggtgaatctc atccaaaaac aggatgcctc
     2161 cgtcagcttt ctccaccagc cctgcttttt catgatcagc gcctgtaaac gcccctttaa
     2221 cgtgaccaaa gatgtgggaa agtagcaagt gggggttatt gaaataatca gcgcagttaa
     2281 aaacgataaa tggcgcatgc tctgaaaacc gcttcatata cttgccataa tggtacatca
     2341 acctggcaaa catagttttt ccaacacccg tctgcccgac tatcagtgta tgcagacctc
     2401 taggaggata cagaatcgct gccttcccct gctcaacctg gttacgcatg ctgcccctga
     2461 aaccgatcaa ggcatggaat ggatcgacct gttcgtcagg cagcaatacc tctttgatgc
     2521 ttttgacctc aatttgtttc tctttcagcc gaacccgaaa ggtgtcctcg ataatctgct
     2581 tgtgcagaaa tctgaccggt cttcctttga ttttaaggat taaatcgtca cgcagcagat
     2641 tattcaactc tttgctcaca ttgtttctca gcatcttttg atcatcagca atttccgcag
     2701 ccgtaatccc ttcccccgca aataaagcct ctttggaaat tttcttggtg ctttcggcaa
     2761 tatactctaa aatcttatct attcttttca cctgtattcc tccagcctga atcagtcatt
     2821 ggaaattgat ttcaacctgc ttatttaggg aacagaatat ggtttttcag cgcatgagct
     2881 actccatcct cgtcattcga gagagtaacg gtgttggcag cagctttgac ctcaagggga
     2941 gcattttcca tggcaatgcc cagtcccgca aaggccagca tgtcgatatc attgtagttg
     3001 tcacccatag ccagacaatc gctttgtttc agttggtact cttttagcag aatttgaatg
     3061 gctgccgttt tggaagcctt ttttgacatg atttccagat aagtaggctt ggataagtag
     3121 agatttactt cttcgccgta tacgggtcgc aatacttgaa ggacgcgtct gatctcttcg
     3181 ggatcaccca tgcacaaaat tttactggtt ccatcagtct cttccctcca accattggta
     3241 agcttagaaa aactataaat gcgaggctcg atattggtga tgtcacgttc ttgaagcgcc
     3301 catgcatcca attgctcaat ataccactca tcatccttat acaggcttac gtgaagatca
     3361 taggcagcca ggctgtcaag caaacgctgt gtcatttgct tatctatata acgggtgttc
     3421 agcttgttcc cgtgtttatc tataacaagt gccccactgt agcatatgag aggctcagaa
     3481 ataccaagat gcttctgcaa tggaataatt gcttttggca ttcgcgcaga gacaagaacc
     3541 actggaatct gcttatcatt tataacctgg agaatggttt ctttggttgc ttccgtgatt
     3601 tgatgcgccg agttaagcag cgtcccgtca atgtcaatgc agacaatttt ataagtttcc
     3661 ataaatgatt cctccagctc cagtgtattt tgttattcaa tgaatgagta tacaagaaag
     3721 atagtgtata taaccaaaaa tacaacacac ataataactg ttacttatta cgacaagctt
     3781 tggcttgttt atgaatcgtt tctatcagat aaaattactc ggtaacgtta acatctaggc
     3841 aggagaattg cataggctta gagaagtaga tctttcataa atgactgact gtgaatttgt
     3901 actggaaatg cacggaaaag gagtttgaat aagtcaatga tacgatatgg attacaacag
     3961 gaacaaggat tcaagctggt tatgacgccc gaattgcgac aagcaatcac gatcttgcaa
     4021 tattcttcgg ctgatttaat atcctttctg catgaacagg cgaacgataa tccagtcatt
     4081 gatttgccgg agtttaatat gtccataggc agtatcaaag aagaagcaga gcggttttca
     4141 cagaaagatc aaggagatct gcttgaacat tatcgtggcg gagaaaaata tccatcggtc
     4201 caacgagcaa accccgttac atttctggat tttgtcccca atccgaatga taccctgttt
     4261 gaacatctga acaggcagct tggactggta tgtgggctta caaattcaca gcgcatggtg
     4321 gcacggtacc tcattggcaa tttgaacgaa atgggatatt tagaacttga tgttccaaca
     4381 gtcgcctcac tattggacgt tcccatagcc gaaattgagg atatgctctt ggtgatacag
     4441 agttttgatc caccggggat cgcctcttac agcttggaag aatgtcttct tctccagctc
     4501 cagcttgctg gcatggatga tgaatgcata gtcagaatgg taagcaacca tctggccgat
     4561 ctggcgaaca atcggataca aaaaattgcg gatgctcttg aaatcggtag gcaagaggtt
     4621 atacagatgg ccgatcgaat tcgcaagcta aatccatgcc cgggcgcagc atttgctcat
     4681 aaagagcagc aatacatcat agcagatata acggtcgaaa aagccaacgg ggaatatctt
     4741 gtcctgatta atgacattag tgcgccgcgg gttgagatca acccttttta ccggcaaatg
     4801 atgcaggatc taccgaatag tgaaaccaaa cgttttatcc atgagaagat gaatacggca
     4861 aaatggctga tcaatagcct gaagcaacgt cggctgaccc ttctacgggt tgccaaggcc
     4921 attgtggaaa agcagcagga tttttttgag catggcgtgt atttcctcaa accaatcacc
     4981 caaaaggaga ttgccgataa gacgggctta cacgaatcca cggtcagcag ggcggtcagt
     5041 aataaattta tacagacgcc tcgcggattg ttcgaactca aattcttctt tacttcctcc
     5101 ttgacgtcag ccgacggaga tgcggcttca tcggagagtg caaaaaagcg tatcaaaaat
     5161 ttgatagatg atgaggacaa gcaaaaacct ttatcggatc aggctcttac taccctgctg
     5221 ggaaaggaag gtttgcatct atcacgcaga accgtggcga aatatcggga agaactgaga
     5281 tatctttctt ctgccaaaag aaaaaagttt gaagtttgaa tgtttaagga atagtcgcgt
     5341 ttgatccggt tccatatttt tcgatttggc ttgatccaga atgatccgac tcgctagttc
     5401 ttgaattcac tattacaccc cctttcttga actaggatgt tttcactttt gaaacgtttc
     5461 caatttgctg taagaaaaac gtcagttagt agatccctac tatgaatcga ccgaatgagc
     5521 taatattttt acaataaaat tatgtagttt cgccttgctt gaagacaatg gggagacgat
     5581 acacttgctg atctaaagtt tcaccttcga ttttcttata aagcagtctg attgtcatac
     5641 gtgccatctc ctccactggc tgcctgattg tagacaatat cggatgaaaa taaggatgat
     5701 cctgaatccc gtcgtagccg ataaccttta catcctctgg aacgcgaatg ccctgcctgc
     5761 gtgctctttc tatatagttg gcggctaaca tatcggtaat agcgaaaatg ccgtccacat
     5821 cgcgatgctc atttaggaac tcgttaaaat aggcatcgtc atccactata gggtcgggct
     5881 tctcgtagat tacataatcg actcccaatg tttgcgcctc atgaatgaaa ccttttctcc
     5941 gattcatggt ttcactgaaa acggaagtga cgcttcccat aaaagccggt ttctgggctc
     6001 ccactttaac aagctccctc aaagccagac gccctccctc ataattatcg gaggtcacac
     6061 aggtaatttt tttgttgaag tgcctatcaa tacttacaat cggaatgtca ttgcttacgc
     6121 tattctctat atcattgtaa gtaatgccga caataccagc cactttgttt tgccgtagca
     6181 tatccagata atacagttcc ttttcgggct tgccgccgct attacataac atgagcttaa
     6241 agccttcccg atccaactca tcctcaatgt aataagccag ttcagaaaaa aaaggatgcc
     6301 aaatacttgg aagcagcaag gccaccatct tggatttcct catcttaaaa tttcgagcga
     6361 cttcattagg aaaataattc agttcttgta tagcttcctc cacttttctg cgtgtatctg
     6421 gttttacaga gcccgagttg ttaataactc gggatacagt tcctacagct acgccagcta
     6481 agctagctac atctttaata cttggcatct ccctccccct atctctcttt atgaaaatta
     6541 taataacact aagatggaag cgtttcaatt ttgttgatgc tcttttttcg ctgaagctct
     6601 ttatcttcct taccgggctg aagcaccagc gcggattcca ttaggtatac gtccttgtcc
     6661 tctacatctg ttcatattca tctctatcct tcttgtttta gtatggccac tttttgaagt
     6721 ccttctttta caatcacttc tgcgcgatcc ttgtactgaa atgtccttcc ataataacat
     6781 cggtagtttg aataattctt cataaatcag atcgtggatg cttgtagtgc ataatagact
     6841 gcaagtttct tttcactata gagatcatag ggtcaagttc taaaaagcaa taaaataaac
     6901 attctccctg tgtgttcgct atagaaatta ttcaacataa cgtacaaacg tataatatat
     6961 tgatacttta caacttacgt tatatactat tataaaattt atacactggg ggtaaggtta
     7021 aaatgtccat agcttcggag ttgagcggaa cgaagcctga ttcactcagc tttttacatg
     7081 gggttaaaga ttgtattcct acattgctcg gttatgtatg tattgggttc gcggcaggca
     7141 ttgtgggtgc ctcatcaggg gttagcacca tggaaattgc cttcatgtcg gcgcttgtat
     7201 acgccggagc ctctcagttt attatgtgct cgatgctggc tgcagccagt cctccatccg
     7261 tcattatttt aacgacattc attgtgaatg ctcgtcatct gctgttaagt gcgtcgctgg
     7321 ctccttactt ttctaaatat tcattgtgga aaaacatagg catcggcgct cttttgacgg
     7381 acgaatcctt tggagtagcg tcggataaat tggctaaagg cgggcaggtc agtgaccgct
     7441 ggatgaacgg acttaatatt acagcttatc tcgcctggat tgtatcctgt gtggcgggag
     7501 gggttctcgg gaactggatt tcccagccgg aggcttttgg tctggacttt gccttgcctg
     7561 cgatgttcct tgccctgctt atttcccagc tccaaagtgt ccagacctcc aaactcaagc
     7621 atcgtctgct gcttgtgcta tgtatggctg ttctgatgta ccttttggcc tggtgggtgc
     7681 catcacatat cgccgtcatt gtagcaacca tgatcaccgc aacgattgga gtgttaaccg
     7741 acaaatgagc attaatccca atgtcctgta tatcattatc ggtgccatgt ttgtcacagc
     7801 catcccaagg atcattccct ttgtcgtgct gcaaaggctg gcgcttccca aaccagtgct
     7861 acaatggctt tcctatattc ccatctgcat attcacggcc ctcgtgatgg agaatttgct
     7921 cgtccgaacc gaatcctccg tcactcttaa tgggcaagtg cttatggctg ttcttcctac
     7981 gctagtgacc gccttgtgga gcaaaaacct gctggctacc gtcgttgtcg gtattgtgag
     8041 tatggcttta gttcgactat tgtggtgaag ataaaaatta ccctcctaca ataggagggc
     8101 atctgccatt tcttatgatc cacctgtcgt ccttactaac gagggcgaca gatcttcttc
     8161 ctcaaagtca cattctcgtt gtgaaagata cgaggaggct tgaagcctga acatttctgc
     8221 atacactccg tctatatcca ttaagcgttc atggctacct gcttctacaa ttctgccttc
     8281 ctccattaaa ataatggtat ccgccatacg tgcggaggac aatctgtggg atataaacac
     8341 tccaattttc tcataaataa gctgatcaaa cttttgaaaa acctctttct ccgcatgtgg
     8401 atccaaaaaa gagctcggtt catccaagac atatatatcg gcatttctca taaaagccct
     8461 ggctattgca atacgctgcc actgtcctcc agatagctgc tgtccatctt caaaccattt
     8521 tccaagcaag gtattcattt tatcaggcag gccgactatc aaatctgtaa tccccgcctt
     8581 atctatagct gtccaaatag cctcatcatt ttctctggaa gccacattac caaagcctat
     8641 attatctcta acagccatct cataatgtac aaaatcctga aaaacaacgc ctatcttttc
     8701 tctaaaaatg tctttatcca attcatgtat agagtatcca ttaattaata tttctccttc
     8761 aaaatcggaa tacagatgag ttagtaactt cacgatcgtt gatttacccg atccatttct
     8821 ccctacaatg gccagcttct ctccttgatg aagcttgaag ctaacattag aaatggcatt
     8881 ctcctccgtg ttcgggtatc taaacgatac attccgaaat tcaatactat gaatagtgga
     8941 caaaggcaat tgctgaaccg ttttttgtat ttttgcctct tccggcatat ccaaaaagtc
     9001 aaatagctgc ttgatataca aattattttg acacaagctt aaaatccctt gtacaatgct
     9061 ctgcgatgtt gactgggtta acgtgatacc ctgaattaag ctcaccaagt tccccactaa
     9121 aatttgacca acataagtgg cttgtatggc catgaaaata ataaatgcac acgcaccctg
     9181 atttacaatc tgaaatacaa gagaagtata ggatctacga accgctagca ctttatcctc
     9241 gcgataaaac ccttcgagta tcgttttata tctttttcgc agatagtctc ccaattgaaa
     9301 tattttcact tctttaaaac tattatctct tgtcactaaa aacgacaaat accaagattc
     9361 acgttgtctt cctgctcttt gaaagtgaac attaaattct ctttgcccga tacgtaaaaa
     9421 agaataaaat gataagcatg gaatgagaaa aatgaataag aatgcccacc atctccatgc
     9481 gatgagaatc gcacccgtcg aaaataaggt tacaacactg ctaataatgg caaggatttg
     9541 agtaaatatt tcaaacggcc tgaaatctgc ctctccctga gcacgttgaa gcatattttg
     9601 cacatctgca tcctcaaacg actgcaaaga catcttttgt gctttttcaa taattttgat
     9661 atttacctgg ttcgatagcc ggctttgaaa cattttacga aaaaagcttt cgccaatatt
     9721 gatcagatcg tacagcaaat tgacaccgat caagacgcca aaagctataa aaacaggttg
     9781 aaagcttccc cctgacgctc cggccacgac actgttgatt aattctctcg tagttaaaag
     9841 gatcacagca ggaattgcac ccttcaataa attcgtaatg agtatagcaa tcaaaaagga
     9901 aggatgtgtg tcccaaagca gcctgaatat acgaggccaa aataaaaagg tacgaaatat
     9961 atttttatag gacaaagaga tcaggtcatt ggtttgtcca tcagactgtg acatagctta
    10021 cccctttccg atgcaaaagg ttagctactg tgtgcttagc taaagccata cattttattt
    10081 ctcgctccct atttacacca agcagacgat tcaaatgcat atgaatgata ctgcccaaaa
    10141 tatcatcagg atgattggta agctcgtgat tatttttagc caggataatc gcttgagcat
    10201 actgctgaat catagcctgt cttttttcta caagcgctaa gaaagcaacc tgtgtgttcg
    10261 tatctgtttg tccaatccat tcataattcg attctacagc ggtaatcaat gtttttttga
    10321 catccctgaa tgccttcata tgaggcttgc aatcaattct ctcttctagc catttcactt
    10381 gctcctgaat cgttaaacca aaaccactca gataatgaat aatgttcatc acagccgcaa
    10441 tctctatgtc cagattgaaa gcattagagc gaattccctt catataggcg atgacccatt
    10501 gactatccac gtcaaaaacc tgttctgcca gctccataag tgtctgtcct ccatacctct
    10561 ccaattcagg atggtatgta tctatgacca tattcgttat tagcccctct tcacgtaact
    10621 cggctgccca ctgatttaac tgcgccaaac cagctgtcca tagcttatcg ggctctccct
    10681 gaaaccgtag gcggatatga tgttcaggat caacgtatcg caaaaagtaa aatttttgac
    10741 tccaatcctt aaaccccggc tgttttaaga gatgccctag gcttaagcct accaggtcag
    10801 tctctctttc cttgactccg tacaatttaa ggtatagcca ctcccctcct ggaaatatgc
    10861 ctctatgaat gctggaagga gtatgagcaa tgaagttttg agaaacaata tggttttgtg
    10921 aactagggat actcggtttc acctttattt ttttcttctt tagtggaaac acaaattctc
    10981 ccatatatct tcctgccgtc ccctgtactg gggtatggaa gggattaccc aaacactcgg
    11041 taagaagaag ttcctgtcct tcacgtgtct tgctcacctc atgtagcaat tctttgatat
    11101 ggaaaaggtt gcataggtct aataaaaggc gattatcccc catcgttagg taaacataac
    11161 gcggtacatt ccattgttgt ctccacacat ggaaaagtgc ttctccttct ttggactcgc
    11221 atgattctga aatattcaat gaagctttgc tcagtttcca ctgcgcagca ctaataatga
    11281 tctttttata tactagtctt ggcaaaaaag gggattgctc taatggcccc cagtcaaaat
    11341 aagaccacgt accaatctct ttattggtaa tatccgttag aaatctgaat atatgtggtg
    11401 aaagcttgta attcagcatg tgtgtttgca aggggattat ttccttaccc aaacgtctag
    11461 acttgacata aaaacgatca tgagtagcac ccaccactaa atcatcaata cagagcgtat
    11521 ggtcctcatc tttagaagag gtggttcccg acacaatctc atatgccatt aaatttttgc
    11581 ttaatgagat attagatatt ttcccctgtt ccggcataaa aaccatctct gacaataacg
    11641 catcgggatg aaagcatcgg tgatgatcat atatttcaga gaatttttgt acaaactcct
    11701 cactcaacat atccagaaaa cgtccaaagg ttttacccgc tctattcgag ccagcactgg
    11761 ctccaagtaa aagcgaatag tctccagaat caactttttc aggagaatca gcaaatatac
    11821 tataatagat ctccattgat tctggggaag tgtcgtagtt atcagaaatc atcagttgct
    11881 ctaactgttc atctgtaagg gcgagttcta tttcatgatt agaaatggca ttcgaaaccc
    11941 attgaaagag aacagcgttg cgtttaaatg cctccatgcc cattgatttt ttttcatttg
    12001 aacgatacat ttccggtata cccagacccc aatcctcatc aaacagttca tgaataggaa
    12061 cctcctgata cacaccgtac ttttccaaga aacgattcaa atattcatcc aattcgtccg
    12121 ttttggggga tgcatataat ttgcacatga cttcagcccc taatgaaacc tcatcaagta
    12181 catgtttcgg cagagttaca tctttatcca atttaacatc aacttgtaca ggtgttttaa
    12241 cagaaatgat atccagcatt ttgtcacata atttccggta gaccttctct ccttctccaa
    12301 ttgtacattg attatattga agtaataagg catcaatttc gtgtaaaatg tgaacccaag
    12361 gatcggaaat gtccagtttt ctaatttttt cgaatatgta atggaagggt gaatgatcca
    12421 ttaacggagg tctaagctcg ctcaagataa actcttgctc tactagttgc tgcaaataat
    12481 cagatatgat ttccaaagta gcgtcaggga atgcctttaa tagtatttct ttgagttcca
    12541 tcacccgaat tggatgttca gcagcttcaa acgtcattcg aacaacgtca gtaaaccgaa
    12601 tggaattaaa aatttctgcc gaatcatcag cttctgctgc tccatgctta ggtcggaatg
    12661 gtaatttggc tcgatttcct ttgatcataa ccgttttgtt taggaagacc tttagttgat
    12721 taaatatggc cggatcagct tctatttttt gaatcagttt atatatccat tccatgtcgg
    12781 gtctggctct cttcagatgc ttaggatagc taccaatatc cagatcggta gtctttccgc
    12841 aaatcccctg ccccactcct gaaaacaacc caaatggagt cgttcgggta gtcatccgaa
    12901 taaaataccg ataaaagctg ttcagcgtct tctcatactt ttgtagctct cctttatcat
    12961 ccaaagcatg gccatcattc aagtaatgta aaaactgcat tagggacgga gaggctaatg
    13021 atatggcttc ttgaacaaca gcttcttggg atatcaactt taatcgacga gttatttcct
    13081 ccaaagtaag ctggctgtcc acatcttgat ccgaaaacac ctgaaaatat cggtctagcg
    13141 gtagtaatgg agctctgatt agaaagaaat cacatgcact aaaccatctt tcatcccgat
    13201 ctctcacttc attatgtagt ttttgcgcat cagtataatg cagttgtctc ttcacaactg
    13261 accacctcca agtttttagg aaatatattc aacttgtaac cgattccatg acatgttacc
    13321 aaaatttttg gatgacttgg atcatcttct attttctctc tcaattttcg gatgtgcaca
    13381 tacaccgtat tagacgtagt aaaagcatcc actccccaga ctctgtctat aatgtgatca
    13441 atcgtagaag cacactcttt tgcagtaaga agatacatta ataatcggaa ttccatcata
    13501 gtcagcgtat gctcatgccc ttgcttccaa ataacctttc cagcaggatc aaaaatgaca
    13561 ttgggtgata aactaatagc ctgctgttct ctttccattc catattcagg tgaagccatt
    13621 gaaaacaatt gtttgaggag atccaattgc cgttggtcat cactatgata ggaaagaaag
    13681 ataaatggaa ccgtaaattt ttctttaatg ctgtgccagt aagacaagtc ctctagcgtt
    13741 acatgatcct gattcaaagc tacaccgata cactgctcat caatctccgg tatagcctgg
    13801 taaagcgaat cataaaacat gattcgaatg ttttctggag tgtttaaagt ctcaaaaaaa
    13861 tgcttaatct tcctaaaaga tgatataacc ataaattttt gtttcatcta atccccccaa
    13921 aaccaatgct tcagataaag caataaggta gcacccttaa gaaattagaa acaattcact
    13981 ccatctccct gaatatttag gatgttcttt cccaattcca tagtccagta aacttaacgc
    14041 aatccctgtt gccccttgca gtattcctac attatgaaca tgagttgtcc cctccaaatc
    14101 ctgatatcca aatgggagct cttcatcgta taaatttact aactttaaag ctatctgatc
    14161 ggcaaaatgt aacgctgcta tattgtcggt taagttatag aatctatgag ctatatgaag
    14221 caaaccagcc aacccgtgac agaaagtagg ggatagcgcg tttagtagct catcatctaa
    14281 gcaaaatatg gattgcatag ctttttccgc tatctttttc cattcttcat tactgcactc
    14341 aattcctgct ctgaataatg tccaacctat tccaaaggtt ccatgacacc agccttcaat
    14401 ttctctcatc cctacttttt tctctctctt gttcattgaa ggcgcttgag agtttacagg
    14461 ccaataccag ccatattgat cctcctgaat ttgaataagc aaaaaatcgg ctatatgttt
    14521 tatagcctca tgtagtcctt caactttgat ctttttttgt agggcagtga caagcagtgc
    14581 aagtattccg gtgataccat gcgccaaacc tagatggatt gaagccgaat cttcccttga
    14641 cgacaaatgt atatattcag gtataaagtg cgtaatggta tctaataatt gacgagacag
    14701 atcacacatc gccttgtctt cagcaacctc cagagtgtat ctgcccactc caagcagtcc
    14761 attgataata tccatttgcc tactgaactc cgtagttgtg ccaattacag gtaaatcccc
    14821 ccactttact tcaatatact tattaagctg agagattagt ttgttataat tagctctgtt
    14881 attggaagct aacaatatgc cataagctac tcctgttgtt ccataataaa gagaaatacg
    14941 aggtaataat aatagagagt tagcatctaa gtaccgtaac tgactatgca catgctctgc
    15001 ccaattttga tcaggctcca ggtatcccca ttcggacaac agcactaaca cacccggaat
    15061 tccatcggca agcgagctag gattccaagg ggaatttcca cgtgaaggtg aaaggttgtt
    15121 tgcatgatta actatctttt ctgtatatga taggtctatt agcttttgtg ctatatactt
    15181 actgatttca actgatctcc cctgcaaatc ttcagccata aatccttccc tcattttcat
    15241 aactggaaaa gacacggtta tagaaaccgt gccttttttc catgtatttt cgttattaac
    15301 acgttttgca gaaggtaaga ctaacttgac aattcaaagt acctgttgca catgaaggag
    15361 tacagataag accactggct ggttgaaccc cttttggagc aacctcattt ttggctactt
    15421 gcaagtccag atcaaattga tttttcatct tgttacctcc ttttattttt tacaatttta
    15481 ttataagtta tataatctta actagacttt atatatttct tacatttgtc ttaatttcaa
    15541 cgaatacatt taagataaac ctttattact ttttagtatt tttaaggaca gcacactaga
    15601 ttttagtgac aatataatga gggaaaatat aatggaggct ttcatatgaa aattgatagt
    15661 tttgttatac aacaatccga ccaagttcgt gcaagagata ttagtaaaaa aattgcttta
    15721 cgtctgtgcg agcccgaatc cgtctattca gcagtccatt cggaacacaa tgtttcgcca
    15781 gaaacaaagt accacccatg gggagaaacc tcactttcgc atggttatcc tggtaacatt
    15841 catttactat cgcaatggcg tgctacagac ctttcgtatg attggaatag agccatacat
    15901 ttaaatatgg ctcagatcca atcctcactt gctataaatg gtcttcacga cctctctctt
    15961 tacagtggct gggcaggcat tgctgcgtcc gtaagagagg cttctaatta tggagaatac
    16021 tacagcaatt tttcacagca aatacatcaa tggatgatgc ctctaacaga gcaatggctt
    16081 cagtcgaaca cagaacaatt aagtcttcac gaaggtatgc ccatgcaatc ctttgacacc
    16141 atttcgggag cttccgggat tggaagatat attttgataa actcaaccaa tcctatttgt
    16201 actcctcttg ttgagccaat tcttcaattt cttaccgatc ttacacatcc catacatatt
    16261 cacaatcatt atgtcccagg gtggtactcc ccacaaaagt ttcaattttt agaccgggat
    16321 aaacgtaact atcctctggg caatttcaat tgtggaatgg cacatggcat tcctggaccg
    16381 ttggctttat tatctgtagc ttatagttct ggaattgaag taaaaggcca atatcaagcg
    16441 attgaaacca ttacggaatg gttgcttaag tataaatatg aggatgaata tggtagctac
    16501 tggcctcata ttgttccatt tgaagctgaa acaggctctc tgcggtttga tttggaacga
    16561 gcaagagaag catggtgcta cggtacaccc ggcatcacct gttccctatt tcttgccgga
    16621 aaggctctcc ataatgtgga actgcaaaaa tcagctgtga aagcttgtgt cggtgcaatc
    16681 tcctatgaga tagctaagcg ggaaatggac tcttctgcac tctgtcacgg tcttgccgga
    16741 ttacttacca tctcttggcg aatgtggcgt cacagtaaag agcctgcatt tctcccgctt
    16801 attcaacagt taacgaattg tctgcttgat cgctttcaaa tggatagccc acttggatat
    16861 ctggaccccg agccaaggtc agatggctct ttgacttggc tgacaaaagc gggcatgctt
    16921 gaaggcgttg ctgggattgc agctgcttta ttaagtgttt ctgagaacaa agagatcggt
    16981 tgggattaca tcctcatgct atcctaacta caaccagtcc ctattcacaa acatcttttt
    17041 cccaccatac agataggcta aaaacgtaaa aatgacaatc aagccgaggc tgtaaggctc
    17101 aactctgggt gcataagtcg ctgtttgcgg catcataata taataaggaa tcgtaaaagg
    17161 aaaccacgca cctatggaag agtgaaagcc tgttatgaca atattaggaa ccacacaaca
    17221 aatagacatt cccagagaag ctccaaaatt ccgaattttt atcgagagca taagctgtag
    17281 tgctgccagg ggaaaaatcc cgagccaccc ccccaaaccg gtagaaagaa cgacagacca
    17341 agggatttct cctggagcac ctgctatatt tccacttaca aaatagccta ctataaatat
    17401 aagctgatca agacccagta tgagaatgag caatatatat tttgcataat aaatttgctg
    17461 acgaggatac gggctgctta ataaaatctt ccatccccca tcccgatgct catacgcaca
    17521 caaaagagaa gcgataattc cacaatagag cggataaaaa aacatagagt gaaattgcgc
    17581 tgaataagta tataaagtta accagctggg cgaaaaaaac tgcttcaaat cgttcagttc
    17641 caggactccc attaaagaat ttatgaccgc atctaatata atgagaatcc ataacatgat
    17701 ccattgaagc tttatcgtct ctacgcgtaa aatagagccc atgtatcttc tcctctctat
    17761 ttgaattcat gcttggtaaa ctgtaatgta ccaagtcccg taaagatgac tcccgcactt
    17821 aaagcaacga tcacccaaat catgtgttcc ttcatcagag gacttgatag tgcagggtac
    17881 gaccaaggca atattttaat ccacagaata cttgtgcgtg ccaaaaacaa gcttgcaata
    17941 gaaccgaata taccaaacgc taatgggaat gcctgattag tgaaaagcgt agacagccaa
    18001 agttgaattg caagtactgg tagggtagcc aagcttgcat taatcggctg taacagcatg
    18061 atccgccaag gaatgggttc gtttgtatat aacacccaga tgaggctcat acctgctaca
    18121 gtgatcaagg cagtacccaa ctgcagaatc acgatccata cgattttgga taaatagata
    18181 tagcttctgg gaacaggcat ggccataagc tgcttccatg tttgagtatc atgctctgta
    18241 ccggccataa tgctcgccaa aagtgtaccg ccaagcagca tcacaaacga aaggaacata
    18301 aacataacgg caaaaccagc atagacacct cctggtcctt gccgaaagta aagataccat
    18361 tccacggcag tcatgcctgt aagtacacac ccctgtataa gaggaatcca ccagcatatt
    18421 ttcttcagct taagcccctc tgcctttata acccggagta tcataagctt cgctccttac
    18481 ctgtcaattc caggaatatc tcctccaatg tttttttctt ctctgtgacc cgataaatgg
    18541 gatgattgtg ttccacaagc accttgatca tctccgaaga ttgttgccga tctacaatag
    18601 gagtcacgac ctcattttgt tcaattgatt cagctccggc cgtccatcca tgctgaatca
    18661 gtgcaccggc agccagaaca ggatctgggg tttcaatgaa taattgaggc ttgcttttgg
    18721 cggtgagttc cttcattgtt ccctggaaaa tcatttcacc ctgattaata attcctacat
    18781 aggttgcaat ctgctcaatt tcgcttaata aatggctcga aaccagtacc gtcattccgt
    18841 aagcgccagg aaggctcata attaactccc gaatttcctg aataccagac gggtccaaac
    18901 cattcgtcgg ttcatcaagt atcaataatt tggggttcgc aataagcgcc atagcaatcc
    18961 ccagtctttg tcgcatcccc aaggaatatc cctttaccgg acgatacgca tccttgctta
    19021 atctcactaa atccagcact tcatgaatcc ttcgggtcgg cagtccacgc atggttgtaa
    19081 cgatttccaa atttcgatat gcagataaat gggcataata ggcaggtgat tcaaccaagg
    19141 agccaatatc cttcaatatt tccatacgct gatcctttag ctttttcccg aaaatctcaa
    19201 tttctccgga tgtggattta atcagcccaa gcagcatacg aatcgtggtt gttttacccg
    19261 ccccattagg tcctaaaaat ccataaatct gctgtccggg tacctggaga tttattcgtt
    19321 ttacaaattc ccgttttcca aaacgcctag ttagctgctg tgtatgtatt acatattcag
    19381 acatttcctg atctcctctc gacttctaat gctgaagctt aagttacata cagtttactg
    19441 aagtaaagta aacatcaggt aaacagtccc taaacaacag gcaaaaaaat cgagcgaact
    19501 ccaaaatgtg aggttagatg ttaaaaagtt agatgtttag cggcagtgaa atctccatcc
    19561 ttgtacccgc tttactgcct ggaaggatat gaagtgttcc gttatgcgct tcaataaagc
    19621 ttttggcaat aggtattcca tgcccttggg agtgagatac ctgcatgaac ttattgggat
    19681 tcattcctat tccgtcatct tcgatagaaa taagaagctt atcgttcgct ttgtttactt
    19741 ccatggaaac gtgtgtacct ggaggattat gaatgattgc gttaatcaaa aaattctgca
    19801 gcgctctgcc taataacttg ctatcgaagg acataataca agccgcctcc atggacgtaa
    19861 aagaaaattc gtattgctcg gccgaaggat ggttagcaat atctatgacc gcactacgga
    19921 gaaactccac aatgtcctcc ttctccaatt ggattggcaa tggactttcc ttaagctgca
    19981 tagaagcatt caaatcctga atcaactgct tcatttcagt cactttctca ctgatactca
    20041 tactaaagct tcttctttct tcatcagacc agtcatactc ttgagcagtc agcatggccg
    20101 catatccctc aatataagat aatggtgttt tgagatcatg gcttacacct gctacccact
    20161 gctgttttcg tttctctatt tccactctct cttcctcatt gctgcgcaat tgtgccgata
    20221 agatgctcat ttgttcaaaa acttctttat acaattgata cggaggttta taactatttt
    20281 tctgattctt tttgccctcc ggcagttcca gttcacttag cggtgcttgg aattcccccg
    20341 tcgcaatatt tccaatccat ttaattacat acaccaaagg tttgcctata taccatccgt
    20401 aggcagctat gaacacaaca ctctgcacga taccaagtcc tgtccagaat agatcaatat
    20461 ttatattttg agatgctcca aatatacttt ttataaaaat atataagatc gtgcaaataa
    20521 caaaacatag gacataggcc agtacaaagc ataacgttac tttcataaaa cgaaaggaca
    20581 tcttaaccag agagttcatt cttgctcctc catcttgact gacatcatca ttttataacc
    20641 aagtcctctt acattgatta aaaattgggg gtgcttggga tcaggttcaa tttttttccg
    20701 caaacgggag atatgaatca ctacagtctt ctcatcaccc aagaaggcct cgctccatat
    20761 cgcctcgtaa agctgccgga cactgaaaat acgattagga tgcttgcaca aaaataccag
    20821 cagtagccat tcacgtgccg gacactcgac ctgcttgtcc tccacaaaca acacaccgga
    20881 ttccagttcc agtcggaaat atccaaaatc taaagttcgt aaggtcggtt tcatggccac
    20941 tgtcgaaact ttccgatatt tcattcgagc cttcatacgg gcaacgactt ccagtgggtt
    21001 aaacggtttg gtaatatagt catcccctcc gataccaaac cccattaatt tgtctaggtc
    21061 tgtatccctt gccgtcaaaa aaagaatagg ggcatccgta tatagacgca tttggcgaca
    21121 tacctcaaac ccatcgttat caggcagcat aacatcaagt acaatcacat ccacatgcga
    21181 ttccatcacg acttgcagcg cttcccgacc tgttgcagca tgcttgactt gaaggaaccc
    21241 ttcttttttt aacaccgttg tcagcatatc ccgcagtccc tgctcatcgt ctactataag
    21301 tactgcaatt tcttccataa cccaaggttc tccattcttt ttttacattt tttactttca
    21361 ttataaaagc aaacgggcag aattaaaatc gagttccatc acatatcgtt catccccgtg
    21421 aatatactta ataaccaaca aggccaaact gtgccgtgta tccacttggg gggtgcctaa
    21481 taatgccgga accacgccag ccatattcat tcgtcgtatc ccgcgaagat tggtcgctgc
    21541 atcgcaaagg gtaccaggac cagcaacgtc atcagcagaa ggtcaaagat gtcattaagc
    21601 aaaatctacc cgatctgata acggaagaaa atattattat gtcggacggt caacagatta
    21661 ttaaagtgcc gattcgcagt ctggatgaat atcgcttcat ttataactat caaaagcaaa
    21721 agcatgtagg ccaaggggat ggagatagtc aggtggggga tgtcatcgga cgtgatcctg
    21781 cctcccagaa gcctggtaaa ggtgagaaag ccggcgacca gccgggacac gatattatgg
    21841 aaacggaagt cagcatagaa gaactggaag atatgctgtt cgaggaaatg gaattaccga
    21901 atttacagca aaaagataag gatcaaattg aggttgaatc tatcgtgttc aatgatatac
    21961 gcaaaaaagg catgcaagcg aacattgaca agaaacgaac cattctcgaa aatctgcgcc
    22021 gcaacgcccg tgaagggaaa ccgggcattc atcatattag tccggacgat cttcgctaca
    22081 aaacatggga agagaagact attcctcaat ccaacgcggt gattatagcc atgatggaca
    22141 catcaggctc gatgggctct tttgaaaaat attgcgctcg cagcttcttt ttctggatga
    22201 cccgcttttt gcgccgtcag tatgaaaagg tggaaattgt ctttctcgcg catcataccg
    22261 aggctaaaga ggttacggag gaagaatttt ttacccgcgg agaaagtggc ggcacgatct
    22321 gctcttccgc ttatttgaaa gcactggaga ttatcgacaa acgatatcct ccttccagct
    22381 acaatattta tcccttccat ttctcggatg gtgataatct gacctcggac aatgagcggt
    22441 gtgtgaagct aatcgaggaa cttataaagc ggagcaatat gttcggctat ggggaagtga
    22501 atcaatataa tcgcagcagc acgctgatgt cagcctacaa gaatattaaa aaggatcagt
    22561 ttatgtacta tgtcatcaag gaaaaaggtg aggtatacca agccttacgt accttttttc
    22621 gcaaacggga agggggatcg gtgggatgag taccgaccag aaggagctag aatatgcgat
    22681 atcagaaatt atggagattg ccgatggatt cgggctcgac tactacccga tgcggtatga
    22741 gatttgtccg gcggatattg tatacacgtt cggagcctat ggtatgccca cgcgcttcag
    22801 ccactggagt ttcggaaaaa cgtttcacaa gatgaaaatg cagtacgatt ttggattgag
    22861 taaaatctat gagctggtca ttaactccaa tccctgctac gccttcctgc tggaaggaaa
    22921 ttctttggtg caaaataaac taattgtcgc tcatgtactg gcacactgtg attttttcaa
    22981 acacaacgcc cgcttctcag cttctaatcg caatatggta gagagtatgt cggccacagc
    23041 agatcgaatc aacagctatg aaatggaata cggttcaaag gctgtggaat ccttcattga
    23101 ctcagtactg gcgatacaag agcatgtgga tccacagatt atcaaaccaa ggcatctgga
    23161 taaacagcgc tacatggagc tcaaaattcg ggagcagaaa gaacctggca aacgccagcg
    23221 cccccctggg ccttacgatg atctgtggtc actggacaca gtgaagcagc atgatccggc
    23281 cgaaaccgag ggcatcaaga tacgccagtt cccgccggaa cctgaaaaag atatcgtctg
    23341 gtttattcag gaattctcgg aggtgctgga ggactggcag cgggatatta tgacgatgct
    23401 gcgggacgaa atgctgtatt tctggcccca aatggagacc aaaatcatga atgaaggctg
    23461 ggcctcctat tggcaccagc ggattgtaag ggaactggat ttgaccgggg aggaaaccgt
    23521 tgaatttgca atgctgaacg cttctgtcgt acagccttcc aagcaaagct tgaacccgta
    23581 ctatttgggg ctgaaaatat ttgaggatat tgaaaaacga tgggataacc caacccgtga
    23641 ggagcaagag cgacaaggac gcaaaccggg cgagggtcga gctaaaatgt tcgaggtacg
    23701 agagttcgac tcagacacct cttttatacg caattacatg accaagaaac tgacagagga
    23761 tttggatctg tacgtgtttg agaaacgggg acccgattgg aaaattaccg ataaatcttg
    23821 ggaaaacata cgggatcagc tcgtgttttc acgtgtgaat ggaggctccc cttatatcgt
    23881 cgtcgaggat ggagattacc tgcatacggg cgagttgaag ctcaagcacc agtacgaagg
    23941 cattgagctg gatttaaaat atatggagcg cacacttccg tatgtatatc agctgtgggg
    24001 gcgcaccgtt catttggaaa cattgattga gggtaagctc gccttattct catatgacgg
    24061 taagaaacat catcgtaagt ttgtatagtc atacaaaatc aaatagccag cctaattaaa
    24121 aaaaggtgca ttcctaaaaa ggatatgcgc ctttttttac tatttcatac aaccttaagc
    24181 gaccttcatt tcttgccaat ttcaggacgc ctgtttcgtt ttggatcagg ggtgtattat
    24241 actaatatga taaatgaccc acgggtcata gttgagaagc agaacgagga gcgttgatat
    24301 agatgaacat ccatcccagc tttcgtgaag ttcgtgaaag tgatcagcag gtattcccga
    24361 tcgcctggta cgccgttggc tggtccaagg aactaaaaaa taaaccgctt aaaaagcgac
    24421 tgcttggcaa agatattgtc ctgtaccgtg atgatcatcg tcaggtacat gccatccatg
    24481 cttattgccc gcactgagga gctgatttgt cgctcggcta ttgtcaaaac gggcacatca
    24541 catgcccata tcatgcatgg tctttcgatg agagtggaca gtgtgtggat attccggcac
    24601 atccgggacg ggctattcct gagtttgctc atacctatgc ctgtcccgcg attgaaaaag
    24661 ccggcctgct gtgggtatat cctcaggccg ttggctcaaa gtatgagata aactcagggt
    24721 tgggaacatc cacatcccca cctcctctgg agattttccc cgagctggag gacccctctc
    24781 tcattttgtc tccctacgat tcagtgtgga aggcacatct gacgagagtt gtggagagcg
    24841 tgctggatgt cgctcatttg ccaattgtcc ataacaaaac gatcggtaaa aaatcctcca
    24901 ccgacattca tatcgagttt gaagcggatg ataatcatat tcgggtgaaa aacgggaatg
    24961 gactattaca atataccttt ccacagcaat ggattttgac tcccgccaag gaaggacgca
    25021 gcaagtttat taatttcgtc actttcactc cgattgagca agagttaacg gccatctacg
    25081 gactggctgg acgtaatttt gccaaatttg taccgggcat gagccatatt ttctccagat
    25141 acagtggcaa ggtgctggaa gaggatcggg ccgtggtgga aagtcagcat ccgcgtccaa
    25201 tcccagaagc tctgcgaatg gaggcacacg tccccgctga tggacctcag gttcggtttc
    25261 gcaaccgctg gtacgatttc cttgtcaacg atgagcctcg tgtacgactg aatccagaaa
    25321 ctacttcctc ttaaattcga cgatgtagct ttgattgagc tgttttccac cttccgaaat
    25381 gttctggtac atggataaaa accgggcgga tgggctccat accgttgggc tgtcatagga
    25441 ttggatatcg gtcgtaaccg gagtggtttt acccgtggac tggtcaaaca catacagccc
    25501 tctcatgcct tgctgatcct catcataaat ggaaaaagca agctttgacc cgtcgctgga
    25561 ccagcttcca cggctcatta aagtaccttg accgacgatt cccttctctt tgccctgttc
    25621 atccaaaatg atcatacggg ctggttcgga tgtattccat ttccgctttt caatggcaat
    25681 agacttaccg tcaggcgaca cggcaaagga catggcaccc tctgcaatgg tcacagcctg
    25741 aggatgattg agggtgaacc gattcagcac cggataccct tgtttatcac tgcctgtata
    25801 aaatatggcg ttacccactt tttcgacatg agacatcaat tcagagcgat tcggatcttg
    25861 aaaactcaat tcttcagctt tgccgtccag accaatcagc tggattttac catccggtgt
    25921 gcctgtaatg agatcattct catcgctcca gctcacttcg ttagtcatat ccagcttgcc
    25981 aatcgatgta accttaccac tgcttagttc caaaatgtag ccctgaatat catatttgct
    26041 gctgatgcta ccttcagtaa aaaagacatg gcgctgatcc ggtgatacca cagcaagtaa
    26101 ctgtggagcc ttacgacctg gtgttaaaat ccgctccttg tctgtctcta cattatgaat
    26161 ccacagctgg gttttacgct ccacaatcag ctcttcgtcg ctcagccaag acctcgcgta
    26221 gacatccccc agcctgtcga tagacgatac caccagttcg tccgttactt gcttctgggg
    26281 tgcatccgtg tcaatcacag taagctgttg gcccggtttc ataccgaatg ctggatttgt
    26341 ctctcctgcg ctcttcatgc cgcaaccact gagcaatccc ccggcgatta agccgatcat
    26401 gagcaccccc gtggctttct gtctgaaaac tcttgtacgg gaatcttcgc gatgagagga
    26461 gccgttcttt tgcccatagc tgtctatgtt tttctttatc atgtacaacg gcctccttgt
    26521 taacgatacc cccagtttaa tgcccgaaca tctcatgaat acatcgaatt gtttccaagt
    26581 tgtaaacaag acaccattct agcccagtgc taacaatcgg ccgtttacag ggagctatcg
    26641 tgaaccaaga ggggaagtct aagcgaaaat tcattaccac ttacattcgt atggccgttg
    26701 ccattttcca acccaccatg atctgaagct gtaagctgca actctccccc catgcgctcc
    26761 gccagtctgc gcgccagagg aagaccgagt cccgtaccgc tgtcctgacg agatcgatca
    26821 cgacttaagg tagcgaacgg ctcaaaaatc atgtcccatt tcttcctagg aatccatgga
    26881 ccggaattac gtacatacac catcacagtg tcctgttcta cccgattcga taacgtaatc
    26941 catccaccgt cccgattgta cttcactgca ttatccagca aattcagtac aatatgcatc
    27001 agatgct
//
