LOCUS       NZ_POVS01000008        20525 bp    DNA     linear   CON 15-SEP-2024
DEFINITION  Paenibacillus sp. F4 F4_contig_7, whole genome shotgun sequence.
ACCESSION   NZ_POVS01000008
VERSION     NZ_POVS01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. F4
  ORGANISM  Paenibacillus sp. F4
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 215912)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Genome sequencing and comparative analysis of polymyxin-producing
            Paenibacillus strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 215912)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2018) Infectious Disease Research Center, Korea
            Research Institute of Bioscience and Biotechnology (KRIBB), 125
            Gwahak-ro, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-JAN-2018
            Assembly Method                   :: CLC Genomics Workbench v. 11.0
            Assembly Name                     :: F4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 524.4x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002894905.1-RS_2024_09_15
            Annotation Date                   :: 09/15/2024 04:37:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,419
            CDSs (total)                      :: 5,299
            Genes (coding)                    :: 5,203
            CDSs (with protein)               :: 5,203
            Genes (RNA)                       :: 120
            rRNAs                             :: 10, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 102
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 42 of 96
            Pseudo Genes (incomplete)         :: 67 of 96
            Pseudo Genes (internal stop)      :: 14 of 96
            Pseudo Genes (multiple problems)  :: 22 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:44:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 178279
            Orig. end                         :: 198804
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            POVS01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20525
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="2"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..20525
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20525
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10525](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10525
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     gene            109..477
                     /locus_tag="C1T21_RS06755"
                     /old_locus_tag="C1T21_06755"
     CDS             109..477
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686510.1"
                     /locus_tag="C1T21_RS06755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06755"
                     /product="DUF2634 domain-containing protein"
                     /protein_id="WP_103047704.1"
                     /transl_table=11
                     /translation="MQSFKLTADGDLEFDSRGELVLIEDDEELAQCCRVALGTNEGEWF
                     LNPEIGLAFRLFLGKLASEEEMRNELTRALLQEERIESVDDVTFSVDRAARLLTVTFKA
                     TGTNGEIIQQEGVSINAG"
     gene            467..1654
                     /locus_tag="C1T21_RS06760"
                     /old_locus_tag="C1T21_06760"
     CDS             467..1654
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686511.1"
                     /locus_tag="C1T21_RS06760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06760"
                     /product="baseplate J/gp47 family protein"
                     /protein_id="WP_103047705.1"
                     /transl_table=11
                     /translation="MLDEKGFKRKRFDDLIDEMEDKAKEVYGDKINTSALSPLGIILRI
                     FAWFLATVWGLAEKVYYSAYVNTAEGASLDRLGPHVGVSRILSQYATGSVTLTGTSGYT
                     VPSGFLVSTDSDIQFETTAESTFPASGSMTVPVEAMEAGLSGNVPEGTVTIIVNPVPEV
                     TAVNNPAAILGGRDKETDPEFRDKFSLSVAGGGSATGDAIRGAVLRVTGVRAAAVIINN
                     KIVPDAAGRPAKSYQVYALGGSDTDIANAILSVGAAGIESHGDISMQVKDLSGNLQPIK
                     FSRAEVVPVHIKIQVYKSTAYPADGDDQVKSKLVRFIGGADLDGTVYAGLSMGEDVVMM
                     RLAAAAYSIAGVEDVIIELSANGTSYGPHNLVVDVQQVAQTAAEWIEVTRHDFSG"
     gene            1638..2279
                     /locus_tag="C1T21_RS06765"
                     /old_locus_tag="C1T21_06765"
     CDS             1638..2279
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686512.1"
                     /locus_tag="C1T21_RS06765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06765"
                     /product="hypothetical protein"
                     /protein_id="WP_103047706.1"
                     /transl_table=11
                     /translation="MISAVDLIKKLTDVFAKNSNGNIGKLFSIVAGPINELETTFKTIE
                     EWRDISTAKGTTLDLIGGNVGQLRGVATDEIYRIMIKSKIARNLSKGDVNTIIRVIALA
                     VGADYSEIKIQQKFSDPLDPEPAALSLMRLPLEKLNESGIELSQFVQIIQKTVAAGVSV
                     QSIELAGTFEFGSLPEEYDTERGWGSTDDSVIGGRLGAVYEPGKNTDLPI"
     gene            2294..4873
                     /locus_tag="C1T21_RS06770"
                     /old_locus_tag="C1T21_06770"
     CDS             2294..4873
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS06770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C1T21_06770"
                     /product="hypothetical protein"
                     /protein_id="WP_103047707.1"
                     /transl_table=11
                     /translation="MPFNKKLPEWFAEGIEPTTTQKTTGYIPGLKPPAQWFNWHLNTAY
                     LAMQELQQNAVHKEIFESRFDTIDTKSITLNAGVQILNAVKAAPFSLSEITGRMLVNLL
                     GRMGNCESVGLWSSNTTIVTDTANKTSGTSSFKLTLGSVPATASASFLTTPGRKYIAVA
                     DVKNGNTSKIAISINGLAGAAGNEVTSASAFAPSVVRFAATDYFHIVTITGTGAAGNTF
                     NMDSVRVYEISEADYAAAASLTPAQAAAKYPYVDSVMPVRNPYVIRYGENLLPPVYTWV
                     NNNGLTDSNVKILDDYGFSMTTTTVQQWRAAASVKVLPNTTYTLSATHNGLLGVYGVDQ
                     KAVITGGVAGGNVTFNSGNNTALDISLSNKTDTAGTFTGTSFMLNIGSTAKPFKPREDS
                     MLALQTDLYADPVTGANADTVFERDGQYFKSKKWQGLTLDGNLAWIYFESGTGYKVVRI
                     PVTNGVVDSERITKFDGKLVQHVFPLSGPDQSHLSPESGIVGLSISVADSGWADSYTPT
                     LDDIKAYFYGYKAYDANTITPANAQSMTTATWTGTGTKYWVQRVGAANFTQSVPQTSYV
                     GYTPYQLVYRLAKPTVDPVISEGQLTFTEGDNQVEVGTGIVLRERSGINTMPGVYAYIN
                     AEFPLRYKPRNILCVYKNGKKDSRWEVIIRPGTDVFAPIGIAFARLVEGQYDPADIFST
                     TYLMTDTSPVVPFTGSYAANEKTLLADLVDDVQQVNARLSVVENKKADKDNPAWLTPTL
                     LNGWTNHDVTLSQISYLKDSAGYVHIKGVAKPGAMNTNVFQLPAGYRPSRTIVAGVAAN
                     TDSGHDVLGRINIGASGNVAILAVVGITITNTGWVSLDSLPPFLAEQ"
     gene            4887..5366
                     /locus_tag="C1T21_RS06775"
                     /old_locus_tag="C1T21_06775"
     CDS             4887..5366
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280227.1"
                     /locus_tag="C1T21_RS06775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06775"
                     /product="hypothetical protein"
                     /protein_id="WP_103047708.1"
                     /transl_table=11
                     /translation="MKVVPKVNTDGFYLEDEVVDDAFSGVVPFYAQPDNTDQNEDTEPT
                     TPELVGYTVGVPITTPGLFKPQFNLAAWRAYESAVYEAQEAYISAMGEWQAKGRVAEEQ
                     PVYVAPKQPEKLWIEGLTPEQIAELTKPATPSEGDKLRQRLKDLELVITELMLGE"
     gene            5383..5586
                     /locus_tag="C1T21_RS06780"
                     /old_locus_tag="C1T21_06780"
     CDS             5383..5586
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369787.1"
                     /locus_tag="C1T21_RS06780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06780"
                     /product="hypothetical protein"
                     /protein_id="WP_103047709.1"
                     /transl_table=11
                     /translation="MAMSMPRVRICANACITRLERGEPDVIVILDSYPLKEDDRNLVLA
                     EIYSKRPDLAADPVPEQPKEQV"
     gene            5666..5965
                     /locus_tag="C1T21_RS06785"
                     /old_locus_tag="C1T21_06785"
     CDS             5666..5965
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022236.5"
                     /locus_tag="C1T21_RS06785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06785"
                     /product="hemolysin XhlA family protein"
                     /protein_id="WP_258012384.1"
                     /transl_table=11
                     /translation="MEDNLSEVSAVVEETTKALMGIQIQLARMEKTLESVPAMAATLEA
                     TRDLAREAMQSSKSAHHRLDKIEDGQKWLWRTISGSAIAVVIGAIVTVLKMGGV"
     gene            5967..6233
                     /locus_tag="C1T21_RS06790"
                     /old_locus_tag="C1T21_06790"
     CDS             5967..6233
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006676592.1"
                     /locus_tag="C1T21_RS06790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06790"
                     /product="phage holin family protein"
                     /protein_id="WP_103047710.1"
                     /transl_table=11
                     /translation="MDWNTVWSLIDPKLLIVVAVCWVIGIGIKRTPKVPDWSIVYIVSG
                     VAVLLTVWMQGWGPQAVIQGVLAGAFAVYGNQLVKQTKKGADE"
     gene            6233..6850
                     /locus_tag="C1T21_RS06795"
                     /old_locus_tag="C1T21_06795"
     CDS             6233..6850
                     /GO_function="GO:0003796 - lysozyme activity [Evidence
                     IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0016998 - cell wall macromolecule catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013152.5"
                     /locus_tag="C1T21_RS06795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06795"
                     /product="glycoside hydrolase family protein"
                     /protein_id="WP_103047711.1"
                     /transl_table=11
                     /translation="MRKISKAGIGLIKSFEGCRLTAYKPVQTEKWWTIGWGHYGQDVKA
                     GMTITQAKADAMLVEDLAKYEAYVNNPSYVPVTDKLTQNQFDALTSFCYNCGAGSLKAL
                     CKGRTVTQIAANITKYNKSSGRVLAGLVRRREAELALYNKPDITKEKDEIMEKANVIVN
                     GKTIADVKMINGTTYVPLRAVGEAWGAQVDWNSKTNTATVNK"
     gene            complement(7028..7153)
                     /locus_tag="C1T21_RS27805"
     CDS             complement(7028..7153)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS27805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_258012385.1"
                     /transl_table=11
                     /translation="MNNEQFIIWLRAKFAERVKTGCTPMEKAVRCMKTAREFVGL"
     gene            complement(7262..7399)
                     /locus_tag="C1T21_RS27250"
     CDS             complement(7262..7399)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS27250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_180984562.1"
                     /transl_table=11
                     /translation="MRAIDWVLLSTALTNLITAIIGLVKVFKESKKNKKGTKRRVRRKR
                     "
     gene            7521..7682
                     /locus_tag="C1T21_RS27255"
     CDS             7521..7682
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS27255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_167438774.1"
                     /transl_table=11
                     /translation="MAGRPPKKDKKIREAIYFEPELLEWLQEKAEQEKCTVSVLVNRMT
                     AQAKEQEG"
     gene            complement(8140..8775)
                     /locus_tag="C1T21_RS06800"
                     /old_locus_tag="C1T21_06800"
     CDS             complement(8140..8775)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS06800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C1T21_06800"
                     /product="hypothetical protein"
                     /protein_id="WP_103047712.1"
                     /transl_table=11
                     /translation="MKRTLGITVAAIAAVVLLAGCGADKTTIKDETPTQAKVESQPAKD
                     TPKAEPAATKEGAAPAEAEKKADDIWTYYNDAKWTDTWNGVKSSIEKVVVTDRAPKKEN
                     PNDFTASAVGVKFKIENTTKNLYTTYPDQAEIVTSTGEQLKPEMVLSDHIGGEIEEGVI
                     KEGNVIWFLKRGHAADIKWVKIKWYVTEGDGLGMDQKRKEYSVKLELK"
     misc_feature    complement(8882..8896)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.51"
                     /tool="antismash"
     misc_feature    8883..8896
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 22.07"
                     /tool="antismash"
     gene            8936..9271
                     /locus_tag="C1T21_RS06805"
                     /old_locus_tag="C1T21_06805"
     CDS             8936..9271
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818450.1"
                     /locus_tag="C1T21_RS06805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06805"
                     /product="YolD-like family protein"
                     /protein_id="WP_103047713.1"
                     /transl_table=11
                     /translation="MGKKLEGNGLWESSRIILPEHKEGYLRLMKDRQRRGKPELDDQEV
                     QLIEQALIDSYNSRQPVSVTVFSPFDDEVMTGVITVINTARREVKLSRGEDDFSWIKLE
                     DIVSTNF"
     gene            9337..10050
                     /locus_tag="C1T21_RS06810"
                     /old_locus_tag="C1T21_06810"
     CDS             9337..10050
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686530.1"
                     /locus_tag="C1T21_RS06810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06810"
                     /product="hypothetical protein"
                     /protein_id="WP_103047714.1"
                     /transl_table=11
                     /translation="MLSNLLYIIIGVFDALAILLLPLALYMLPIKDYKYKIILFAVAIS
                     LVSFLMRIVLNVPKLDLPLQYALFSMFFRLGLKIKLHWSAFILGVAISAYATMQMAIFY
                     VYKFFDMMQIGVLKENANLQVFLLQGTSILITYLIAALFKLYGTGFSFISAPPHDFIWR
                     EDYRTRENKMVLTSTLFSTVTISLGVILLYYLNPLAILLVSVFTFALSYIFSKRSDEED
                     ARKALEAHRNRNKKS"
     gene            10001..10525
                     /locus_tag="C1T21_RS28430"
                     /old_locus_tag="C1T21_06815"
     CDS             10001..10525
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016526.5"
                     /locus_tag="C1T21_RS28430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06815"
                     /product="accessory gene regulator B family protein"
                     /protein_id="WP_180984563.1"
                     /sec_met_domain="AgrB (E-value: 1.4e-21, bitscore: 70.5,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEKLSKRIATAIKKADPDGPGSVEVLTYSIGIKLNWYSGLILTI
                     LFGWIVGEVLNSLLAFFSFVVLRKFSGGLHFKSLTVCAIFSAALFAAIPLIHLGHDGTL
                     LLTAISAVIVLCIAPRKSEDLNPSGLDPYLKWISLVIVFSNFLIQSPVIALSFTAQTVL
                     LLPLWKGGEQR"
     gene            10522..10647
                     /locus_tag="C1T21_RS27810"
     CDS             10522..10647
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS27810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_258012387.1"
                     /transl_table=11
                     /translation="MKKGIARFVSKRLVQDAEKSSKCEKTLVGAMPVPQELKLKK"
     gene            10658..11380
                     /locus_tag="C1T21_RS06820"
                     /old_locus_tag="C1T21_06820"
     CDS             10658..11380
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS06820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C1T21_06820"
                     /product="hypothetical protein"
                     /protein_id="WP_103047716.1"
                     /transl_table=11
                     /translation="MDNDNREIFAPEVLPDGQYGERYSFFENDLVCVERWIPKSNYEIP
                     FFITMDGNFTAPTTHGEFADGFPNFLSLDTGNLVNLKNVSRAEIGDYGGKVFFGGTDMH
                     TSVNKLNSVILAKLLEAAKKRPDDQRFIVGTVNSRSGLFPAKDICYLDMWGPKKNYHVP
                     RFHHSNGFHVVALTIRNCQEAFPYLFPATPGHLINVSKVAGYDEHSFGAMVKFEGTDYT
                     CPISNPKLKALKKYLKNK"
     misc_feature    11557..11570
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.69"
                     /tool="antismash"
     gene            11646..11816
                     /locus_tag="C1T21_RS27260"
     CDS             11646..11816
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS27260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_180984564.1"
                     /transl_table=11
                     /translation="MQKHIIEVQKELRDDDIEKFVCAMLIIRSIKPPVSIELIMPTKKK
                     LLEVSSLFMGQ"
     misc_feature    complement(11845..11865)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 27.34"
                     /tool="antismash"
     gene            12294..13295
                     /locus_tag="C1T21_RS06825"
                     /old_locus_tag="C1T21_06825"
     CDS             12294..13295
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429533.1"
                     /locus_tag="C1T21_RS06825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06825"
                     /product="polysaccharide lyase family 1 protein"
                     /protein_id="WP_258012389.1"
                     /transl_table=11
                     /translation="MLFTFSASSTFAAADFPNTSTNGMTGFAGQAKSENGATKPATTGG
                     KGGQIIYINNLNDLKNQLGDSTPKILVIEKNISASSKTVVNIGSNKSLIGSYAQNKLVN
                     IHLKTTNNSGNVIFQNLTFEHSANINGNDDIQLYLTAGTNYWIDHVTFAGHNYNANGSD
                     LDKLLYIGQSADYVTISNSKFANHKYGLILGYPDDGNKNYDGMPHITIANNYFENLLVR
                     GPGLMRYGYFHVKNNYINNFQLAYTIATNARIYSEYNYFGKGSEKGGILDDKANGEFKD
                     VGSFPAINNQKSRVTSWNPSKNYSYQVQTPEYTKEFVTKYAGSSNTTLVFGK"
     gene            13661..15511
                     /gene="abc-f"
                     /locus_tag="C1T21_RS06830"
                     /old_locus_tag="C1T21_06830"
     CDS             13661..15511
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="abc-f"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370092.1"
                     /locus_tag="C1T21_RS06830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06830"
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="WP_103047734.1"
                     /transl_table=11
                     /translation="MRTILRIRNVVKDWSGTSLFENVSLDVMEGERLALFGRNGAGKTT
                     LLRILLGDEAPTSGQVEHDLPLEERGWLKQQDTVAWSRTALEAAQQASPRHWRLKQALG
                     QLEADLADAGEDMEHHLERYGELMDEYERLQGFAWESEVEKALTRMGMPVQTWSIAYGD
                     LSGGQKTRVRLAGLMVRQPKLLVLDEPTNHLDAESLLWLEQWLSTYPGTLLFVSHDRAF
                     LDRVATSIVELTSTGIGRYKGGYKEYKAQKERELREQEASYRKQELAKQALEETIRNYR
                     EWFHQAHRGASKVEMAVTQSFYKAKAKKNISRYHAKEKELERLEANRVEQPREAASLHM
                     KLSDSGFQAKYLLRAEQVDFSYDDRIIVKNLNLIVARGDRLAVRGPNGIGKTTLLRLLT
                     GQLEPQTGKITANPQLNIGYFSQELEQLPEDQTLLDSLLALPTMTQTEARTVLGCFLFA
                     KEDVFKKIGTLSMGEKCRVAFLRLYFSGANLLVLDEPTNYFDIETREIVEDSLRNYDGA
                     LVLVSHDRELVRCTATRLLDMKPGGGYEIYEGTADEKQEDERSRQREPEDQERREERLR
                     LQLRLTELMGMTGTNDENEKLLSEIRRIRANLERLDDLDI"
     gene            15725..15850
                     /locus_tag="C1T21_RS27815"
     CDS             15725..15850
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1T21_RS27815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_258012388.1"
                     /transl_table=11
                     /translation="MANVQVGDTGSRPLQRAERDDDAQHEQSPVTSCRKAERRVS"
     gene            15962..16993
                     /gene="pheS"
                     /locus_tag="C1T21_RS06835"
                     /old_locus_tag="C1T21_06835"
     CDS             15962..16993
                     /EC_number="6.1.1.20"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pheS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370093.1"
                     /locus_tag="C1T21_RS06835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06835"
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="WP_269321413.1"
                     /transl_table=11
                     /translation="MSETIQMKEHLLALKEEALEVLEKVATPKELADLRVKYSGKKGAL
                     TEILRGMGKLSAEERPVVGQVANEVREAIEEVVNRKQDEFTKAETNERLQAEKIDVTLP
                     GRALPQGGLHPLNKVIEQIEDIFTGMGYRVAEGPQAETDYYNFEALNLPKNHPARDMQD
                     SFYLTEDLLMRTHTSPVQIRAMEAMKGETPIKVICPGTVFRRDDDDATHSFQFHQIEGL
                     VIGKDIRMSDLKGTLLQFAREMFGESTEIRLRPSFFPFTEPSAEVDVTFVKKNGERVWI
                     EILGCGMVHPKVLEMGGFDPEVYSGFAFGMGVERIAILKYGIDDIRHFYNSDLSFLKQF
                     ARQ"
     gene            17022..19469
                     /gene="pheT"
                     /locus_tag="C1T21_RS06840"
                     /old_locus_tag="C1T21_06840"
     CDS             17022..19469
                     /EC_number="6.1.1.20"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pheT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280577.1"
                     /locus_tag="C1T21_RS06840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_06840"
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="WP_103047718.1"
                     /transl_table=11
                     /translation="MKVSFEWLSDYVSLDQVSAEDLAEKITRSGIEIDEVEQRNQGITG
                     VVVGYVKSKEKHPDADKLNVCIVDAGQEEDLQIVCGAKNVDAGQKVPVAVVGAKLPGDF
                     HIKKAKLRGVVSMGMICSAKELGMNDKLLPKELQEGILVLPEDAEIGMPITKLLALDDQ
                     VLDFDLTPNRSDCLSMHGAAYEVSAILGRDISLADPAKDLVEISDAAADHLSVKVDTPE
                     LCTHYAARYITGVKVGASPLWIQNRLMAAGVRPINNIVDITNYVMLEYGQPLHAFDADK
                     LENGNIEVRLARAGETLITLDDQERKLEPHMLLITDGVKPIALAGVMGGANSEVTDATV
                     SIALESAKFDGGTVRKTSRQLGLRSEASLRFEKEIDPGAVVPAVNRAAALIQRYAGGTV
                     HQGIVESASAKAENRIIKLSLDKINRYLGTELSLLEVKTIFGRLHFGCGDAEQGVLEVQ
                     VPTRRGDITIDVDLIEEVARLYGYDNIPTTPIEGPTTPGALTASQSLRRSLRRLLAHGG
                     WQETISYSFVHPQSTGLFNALTEGSHPVRLAMPMSEDRSVLRTSIIPQMLDTAVYNMNR
                     KQDNLAIFEMGTVFYTEEQTLTRQPQEIQVLSLLLTGVRREKQWNIGAEKVDFFDIKGA
                     LETVFDYFGLSASIRYVADQPQSYHPGRSASVWLDVNGNSQRIGTIGQIHPELQQSYGL
                     NDTYVAEIALQQVVEHANSHIQFRELARFPSVERDIALVVNKDVEAGELLRVIHAAGGE
                     LLQDARVFDVFTGSKLGEDKKSVAISLTYRHWEHTLTDEEINAAHTPVVTSLEQTFGAE
                     LRK"
     misc_feature    17035..17050
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.69"
                     /tool="antismash"
ORIGIN
        1 gtctggccgg gaaggtagct acgccggaca cggcaagaca acatgatagc aatgacgcgg
       61 ttatagtcgg gatattcccg gcttctttta gttagggggt atgtaatctt gcaatcattc
      121 aaacttaccg ctgatggaga tttggagttc gatagccggg gggaactggt attgattgag
      181 gatgatgagg aattggcaca atgctgccgg gttgcccttg gtactaatga gggggaatgg
      241 tttcttaacc ctgaaattgg acttgctttc cgtttgttcc ttggaaagct cgccagcgag
      301 gaagaaatga gaaatgagct aacccgtgca ttgttgcagg aagaacgaat agagagcgtg
      361 gacgatgtta cattttccgt tgaccgcgcg gcccggctgc taacagttac gttcaaggca
      421 accgggacca atggcgagat aatccagcag gaaggggtga gcattaatgc tggatgaaaa
      481 gggctttaaa cgtaaacggt tcgatgacct gattgatgaa atggaagaca aggccaagga
      541 ggtatatggc gacaaaatta atacgtctgc cctctctccg ttgggtatta tcttgcggat
      601 attcgcatgg tttctcgcta ctgtttgggg gcttgcggaa aaagtatatt acagcgccta
      661 tgttaacacc gcagaggggg ccagcttaga ccgtcttggc ccacatgtcg gggtatcacg
      721 tatcctttcg caatatgcaa ctggcagcgt aacacttaca ggtacgtccg gctatacagt
      781 gccatcgggt tttttggtgt caaccgattc ggatattcag tttgaaacca cggctgaatc
      841 aactttccca gcttccggca gtatgacggt tcccgtggag gcgatggagg caggtttgtc
      901 cggtaatgtg ccagagggaa cagtaacaat catcgttaac ccggtaccgg aagtgacagc
      961 agtaaacaat cccgctgcta ttcttggcgg acgcgacaag gaaacagacc cggaatttag
     1021 ggataaattc agcttatccg tagctggtgg cggatcagcg acaggcgatg cgatacgggg
     1081 ggcggtgctt cgcgtaactg gagtacgtgc ggcagcggta attatcaaca ataaaatcgt
     1141 ccctgatgct gctggtcgtc cagcaaaatc atatcaggtt tacgctcttg gtggatcaga
     1201 cactgacata gccaacgcaa tcttatccgt tggagctgcg ggcattgaat ctcacggcga
     1261 tatctccatg caagttaagg accttagtgg gaacctacag ccgattaaat ttagtcgtgc
     1321 tgaggttgtg cctgttcaca taaaaattca ggtttataaa agcaccgcgt atcccgctga
     1381 cggagacgat caggttaagt cgaaattggt aaggtttatt ggtggtgctg accttgatgg
     1441 gacagtttac gcaggcttga gcatgggcga ggatgtggtc atgatgcgtc ttgctgccgc
     1501 tgcctattcc attgcaggcg tggaagatgt gattatagaa ctttccgcga acggaacgag
     1561 ttacgggccg cataatttgg ttgtggacgt gcaacaagtg gctcaaactg ctgcggagtg
     1621 gatcgaggtg acacggcatg atttcagcgg ttgaccttat caagaaattg actgatgtgt
     1681 ttgccaaaaa ttcgaacggt aacataggta aactattttc aattgtagct ggcccgataa
     1741 atgaattaga aactacattc aaaacaattg aagaatggcg agatatctcc actgcaaagg
     1801 gaactacatt ggatcttatc ggtggaaatg tgggacaact tcgaggggtg gccactgatg
     1861 aaatttaccg gataatgata aaaagcaaga tagcccgtaa cctgtccaaa ggggacgtaa
     1921 atacgattat acgggttatt gcccttgcgg ttggcgcaga ttacagcgaa attaagattc
     1981 agcagaaatt tagtgatccg ctggacccgg aaccagcggc gttatctctc atgcgcctgc
     2041 cgctggaaaa gttgaacgaa tccggcatag agttgtctca attcgtgcag ataatccaaa
     2101 agacggttgc ggccggagta agcgttcagt caatcgaatt ggcgggaacg tttgaatttg
     2161 gcagcctgcc ggaagaatac gacaccgaac gtggatgggg cagtacggat gattcggtca
     2221 ttggcggcag gctgggcgca gtttatgaac cgggtaaaaa tacggatctg cctatttaga
     2281 aaggagtaat acaatgccat ttaataaaaa actgcctgag tggtttgccg aaggtattga
     2341 gccgaccaca acgcagaaaa ccaccgggta tataccgggg ctgaaacctc cagcacaatg
     2401 gttcaactgg catcttaata cggcttactt agcaatgcag gagttgcaac aaaatgcagt
     2461 tcacaaggag atttttgaat ctcgttttga caccatagac actaaatcta taacgctgaa
     2521 tgcaggtgta cagatactta acgctgtgaa ggcagctcca ttttctctgt ccgaaataac
     2581 cgggcgaatg ctggtgaatc tgctgggccg tatgggtaat tgcgaaagcg tgggcctgtg
     2641 gtcgtccaat accacaatcg taacggatac agctaacaaa accagcggga ccagctcatt
     2701 taagcttacg cttggttctg tgcctgctac agcttcagca agctttttga ccacgccggg
     2761 gagaaagtac attgctgttg cagatgtgaa aaacggcaac accagtaaga ttgccatatc
     2821 catcaacggc cttgctggag cggcaggaaa cgaagtaaca tcggcctctg cttttgctcc
     2881 gtccgttgtg cggtttgcgg ctacagatta tttccacatc gtcacgatca caggcacggg
     2941 tgcggctggt aatacgttta atatggatag tgtgcgcgtg tacgagatca gtgaggcaga
     3001 ctacgcagca gccgcaagcc ttacgccagc acaggccgca gctaagtatc cttatgttga
     3061 tagtgtaatg cctgtgcgaa atccgtatgt gatacggtac ggggaaaatt tactaccacc
     3121 cgtctataca tgggtgaata ataatggatt gacggattct aatgttaaaa ttttggacga
     3181 ttatgggttt agtatgacca ctacaacggt tcaacaatgg agggctgccg catctgtgaa
     3241 agtccttcct aatactacgt atactctatc tgctacgcac aatgggttgc taggagtata
     3301 cggtgtagac caaaaggcgg taatcacagg cggggttgca gggggtaacg tgactttcaa
     3361 ttctgggaac aataccgcct tggacatatc tctttccaac aaaacggaca ccgctggaac
     3421 gttcacagga acaagtttta tgctcaatat cggcagcaca gccaaaccat tcaaaccgcg
     3481 tgaagactca atgttagcgt tgcaaacaga cctgtacgcc gatccagtta cgggagccaa
     3541 tgcggataca gtttttgagc gtgacgggca atacttcaag tccaagaagt ggcaagggct
     3601 cacgcttgat ggtaatttag cgtggattta cttcgagtca ggaacgggct acaaagtcgt
     3661 gaggattcct gttactaatg gagtggttga tagtgagagg ataacaaagt ttgatggtaa
     3721 gttggttcag catgttttcc cgttaagcgg gccggatcaa tctcacctta gccctgaatc
     3781 cggcattgtg ggcttatcaa tctctgttgc agacagtgga tgggctgaca gctacacgcc
     3841 gacgttagac gacatcaaag cgtactttta cgggtacaaa gcctatgatg ctaataccat
     3901 cactcctgca aatgctcaat ccatgaccac ggcgacatgg acaggtacag gtactaagta
     3961 ttgggtacaa cgtgtcggtg cagctaattt cacacaatcc gttccgcaaa cgtcctacgt
     4021 ggggtatacg ccgtaccaac ttgtataccg actcgcaaaa cctacagttg atcctgtcat
     4081 ttcagaaggg cagctaacct ttaccgaggg cgataatcag gttgaagtgg gtacggggat
     4141 tgtgctgcgc gaaagatcgg gtatcaatac tatgcctggt gtttacgcct atataaatgc
     4201 cgagtttcct ttaaggtaca aaccgaggaa tatcctttgt gtgtacaaga atggcaaaaa
     4261 ggattcacga tgggaagtta ttattagacc gggtacagac gtattcgcac ccataggaat
     4321 agcatttgcg cggttagttg agggacaata cgaccccgcg gacatctttt cgacaaccta
     4381 ccttatgaca gacacatcgc cagtcgtacc gttcacaggc tcctatgcag ccaacgaaaa
     4441 aacgctttta gccgacttgg tggatgatgt acaacaagtc aatgcgcgtt tgtcggtagt
     4501 agagaacaag aaggctgaca aagataatcc tgcatggctt acgcctacgt tgcttaatgg
     4561 ttggactaat catgacgtaa cgttgagtca gatatcttac ttgaaagatt cggcagggta
     4621 tgtccacata aaaggtgtag ctaaaccagg agctatgaat acgaatgttt tccagttacc
     4681 tgcgggatat agaccatcgc gtacaatcgt ggcaggagtg gcggcgaata cagacagtgg
     4741 acacgatgtt ttagggcgaa taaatattgg agccagtggc aacgttgcga tacttgctgt
     4801 agttggcatc acgataacaa atactggttg ggttagtttg gacagtttgc cgccgtttct
     4861 ggctgaacaa taaggaggtc taacacatga aagtagtacc aaaagtaaat acagatggct
     4921 tctatttgga agatgaagta gtggacgatg ccttttccgg tgtcgtccct ttttatgccc
     4981 agccggataa caccgatcag aacgaggata ctgagccgac aacgccggaa cttgtaggat
     5041 atacggttgg cgtaccgatt acaacgccgg gtctgttcaa acctcaattt aaccttgccg
     5101 catggagggc ttatgagagt gccgtatacg aggcacagga ggcgtatatt tccgcaatgg
     5161 gcgaatggca ggctaagggc agggtagcgg aggaacagcc tgtgtatgtt gctcctaagc
     5221 agccagagaa gctatggatt gaagggctta cgccagaaca gattgcagag ctgaccaaac
     5281 cagctacgcc aagcgaggga gacaaactac gacagcggtt aaaggactta gaattggtta
     5341 ttaccgaact tatgttaggc gaatgagggg aggtgaactg acatggctat gtctatgccg
     5401 agagtccgta tctgtgccaa tgcctgcatt acccggctgg agcgcggaga accggacgtt
     5461 attgtgattt tggatagcta tcctcttaaa gaggacgacc gcaatttggt gcttgcagag
     5521 atttattcca agcgtccaga ccttgcagcc gatccagtac ctgagcaacc gaaagaacaa
     5581 gtgtaaccag cgcacccaaa gggatgcgct atttttatgc ccccggagtg gtcgggggct
     5641 tatttatgtg aaaggacggg gaccaatgga agacaattta agtgaggtga gcgcagttgt
     5701 ggaagagacg acgaaggccc taatgggcat acaaatacag cttgcccgga tggagaagac
     5761 tttggagagc gtaccagcta tggcggccac tttggaagct acgcgagatt tggcgcggga
     5821 agcaatgcaa tcttccaagt cggcgcacca taggctggac aagattgagg atggtcaaaa
     5881 gtggttatgg cgcacaatca gtgggtcagc tattgctgta gtgatcggcg caattgtcac
     5941 cgtacttaaa atgggaggcg tataaaatgg attggaatac tgtatggtcg ttaatcgacc
     6001 ctaaattgtt aatcgttgtg gctgtttgct gggttatcgg tatcggaatt aagcgaacac
     6061 ctaaagtgcc ggactggagc atcgtatata tcgtatctgg tgtcgctgtg ctgcttacgg
     6121 tatggatgca aggatggggg ccacaggcag ttatccaggg tgtgctggct ggtgcttttg
     6181 ctgtctacgg caaccaactg gtcaaacaga ccaaaaaggg ggctgacgaa taatgcgtaa
     6241 aatatcgaaa gctggcatag gcctgattaa atcatttgag ggatgccgct taacagccta
     6301 caagccagtg caaacggaaa agtggtggac cataggttgg ggccattatg gacaggacgt
     6361 taaagcaggc atgaccataa cacaagctaa ggccgatgct atgttggtgg aggatttagc
     6421 caaatacgag gcgtatgtaa acaacccgtc gtatgtcccg gtaacggaca aactcacaca
     6481 aaaccagttc gacgcactca caagcttctg ctacaactgc ggcgcgggta gtctaaaggc
     6541 actctgtaaa ggtcgcacag tgacgcagat tgccgccaac atcacaaagt acaataagtc
     6601 cagtggcagg gtactggctg ggctggtgcg acgcagagag gcagagctag ccttgtataa
     6661 caagccagat attacaaagg agaaggatga aattatggaa aaagcaaatg taatcgtaaa
     6721 tggtaagact atcgctgacg ttaagatgat taacggtacg acgtatgttc cgctacgggc
     6781 tgtgggtgag gcgtggggcg ctcaagtaga ctggaacagt aagaccaata cagcaacagt
     6841 taataagtag aacaaaatgt cccagctaac cttaattggt cggctgggac atttttttat
     6901 tcaaagtaat tgcggatact taacaacagc gaaacaatac ttattgccca gccagataag
     6961 gatatggtcc ataagattgc atcatacata gagttacctc ctatagaggg gcatatagcc
     7021 ccgcatttta cagacccaca aactcacgag ccgtcttcat gcatctaaca gccttctcca
     7081 ttggtgtaca tccggttttt actctttccg caaatttagc acgaagccaa atgataaatt
     7141 gttcgttatt catgccttcc tacctcccac gtaaggccgc cgccagattg tttatataag
     7201 tccgttatgt tatgattggg tatagaaggc gctatgtaag ccgccctcta ccaaggaatc
     7261 cttaacgttt gcgccgcacg cgtcgtttgg ttcctttttt gtttttcttg ctctctttaa
     7321 acactttgac caaaccgata attgcagtta tcaggtttgt gagtgctgtg gagagcaaga
     7381 cccaatctat tgctctcaat ttatatcacc tccttacata ttctatttta cagcatttaa
     7441 aatgctttgt aaatagtttt attgagtgtt gcaaaaatat tttaaatgct gtaaaattcg
     7501 cataacagga gtgtgatttt atggctggaa gaccaccgaa aaaagataag aagattagag
     7561 aggctatcta ttttgagccg gaattgttgg aatggctcca agagaaggca gagcaagaga
     7621 aatgtacagt aagtgtgttg gtaaatagga tgactgcaca agcaaaagag caggagggat
     7681 aaggcctcac tgctctttta aataaaaaaa agccctcgac atgaggactt gtggtataat
     7741 ctggattgga caacgggtgg gggtcacggc gcagccttct gtaaaggagg tgattgccgc
     7801 catgactgca cttggtacgc tttatctgct cttgaaagta actgcaacgg tactaagcct
     7861 ttggtttagt tctcgcaagt ttttccgatg gatcagacgt agacgtaaca agcgcaaaac
     7921 ccaccgctaa aggttggtcg cctacggtgg gttttgctgt aatcacagta atatatgcgc
     7981 gccgcgaagg cacacttcgt tgttctaggg gagagttgcg tctcccttat ttctattctt
     8041 atgttatcat atctattcta tacaggcaat gtaattgcct ttgttgccta tagtcaaata
     8101 ttaaaacccc ggattgctcc ggggcttttt tatttgagtt tatttaagct caagtttaac
     8161 tgagtattct tttctctttt gatccatacc cagtccatca ccttcagtta cataccattt
     8221 gattttaacc catttaatat ctgcggcatg gccgcgtttc aggaaccaaa ttacatttcc
     8281 ttcttttata acgccttctt caatttcccc gcctatgtgg tcggacaata ccatttcggg
     8341 ttttaattgc tcaccagttg aagtaacaat ttcggcttgg tctgggtaag tggtgtatag
     8401 gtttttggtg gtattttcaa ttttaaattt aaccccaaca gcagatgcag tgaaatcgtt
     8461 tgggttctct tttttagggg cgcgatccgt tactactact ttttcaatac tagatttaac
     8521 accattccac gtgtctgtcc attttgcatc gttgtaatat gtccaaatgt cgtcggcctt
     8581 tttctctgct tcagcaggcg cagcaccttc tttagtagcc gctggttcag cctttggagt
     8641 gtccttagct ggctggcttt ctactttggc ctgtgtagga gtttcatcct taattgtagt
     8701 cttatcagct ccacatcctg caagcaagac cactgccgcg atagctgcaa ctgtgatacc
     8761 taatgtcctt ttcaactttc ttccccctat ttaaccaaaa attttataga attagtatat
     8821 atgacctagg aatatttttc tagtgcgaaa gttttagatg tggcatataa agactcttgt
     8881 gcggaacaaa tgttcgctat ataatttgtg cataacaata caggaggcgg attcaatggg
     8941 aaagaaactt gagggtaatg gattatggga gagttcacgg attatcctgc cggaacataa
     9001 agagggatac ttacgtttaa tgaaagaccg tcagcggcgc ggtaaaccgg agctggatga
     9061 ccaagaggtg caattgattg aacaggcgct aatagactct tacaactcac gccagcctgt
     9121 cagcgtgact gtatttagcc cgtttgacga tgaggtcatg actggtgtga taacagtaat
     9181 caacacggct agacgcgaag taaagctatc tcgtggggaa gatgatttta gttggattaa
     9241 gctagaggat attgtttcga caaattttta aaatctcttg cttacgtcat gcgccactat
     9301 ataattaagg tagattaatt agataggcgg tgtgaggtgt taagtaattt gctttatata
     9361 attattgggg tgtttgatgc actagctatt cttttgctgc ctttggcatt gtatatgctc
     9421 cccataaagg actataagta taagattatc ctttttgctg ttgctatatc tcttgtatcc
     9481 tttttgatgc ggattgtact aaacgtacct aagttggact tacctttgca gtatgcacta
     9541 ttttcaatgt tttttcgttt aggattaaaa ataaaattgc actggtctgc ttttatattg
     9601 ggagttgcca taagtgccta tgccactatg caaatggcta ttttttatgt atataagttt
     9661 tttgacatga tgcagattgg cgtattaaag gaaaacgcca atctgcaagt gtttttgttg
     9721 caaggtacat ctatacttat cacttatctt atagccgcac tttttaagtt atatggaact
     9781 gggttttcct ttatatcggc gcctccccat gattttatct ggagagaaga ctatagaacg
     9841 agagaaaaca aaatggtctt aacaagcact ctgttttcga cagtaacgat aagtttggga
     9901 gtaatactgt tatactattt aaatccactt gcaatactgc tggtgtctgt attcactttt
     9961 gccctttctt atatcttctc caaaaggagt gatgaggaag atgctagaaa agctctcgaa
    10021 gcgcatcgca accgcaataa aaaaagctga tccagacgga cccggaagtg tggaggtatt
    10081 aacttactcc ataggtataa aacttaattg gtactcgggt ctaatactaa cgatcctatt
    10141 tggttggata gtgggtgaag tattaaattc cctattagca ttcttctcat ttgtagttct
    10201 gcggaaattt tcgggagggc tgcatttcaa atctctaaca gtctgtgcca ttttttcggc
    10261 tgcacttttc gcagcaattc ctttgataca tttgggacat gatggcacgt tacttcttac
    10321 ggccatatcg gcagtaattg tcctttgtat agcccctcgc aaatcggagg accttaaccc
    10381 ttcggggttg gatccgtatt taaaatggat ttcgttagtt attgtattta gtaatttttt
    10441 aatccaatcc cccgtaattg ctttatcttt cacggcacag accgttctct tattaccctt
    10501 gtggaaggga ggtgagcaac gatgaaaaag ggaatcgcac gttttgtatc aaaaagattg
    10561 gtacaagatg cagaaaaatc ctctaaatgt gaaaaaacgc ttgtaggcgc aatgccagta
    10621 ccgcaagaac taaaactaaa gaaatgattt aaacccaatg gacaacgaca acagagagat
    10681 ttttgcaccg gaagttttgc cagatgggca atacggagaa cggtattcgt tttttgaaaa
    10741 tgatttagtg tgtgtagaac gatggatacc gaagtcaaat tatgaaatac ccttttttat
    10801 tacaatggat ggaaacttca ctgctccaac aacacacggg gaattcgccg atggattccc
    10861 caatttcctt agtctggata ctggtaattt agtgaattta aaaaatgtct ccagagcgga
    10921 aataggcgac tatggaggta aggttttttt cggtggaaca gacatgcata ccagtgttaa
    10981 caaacttaat tcagttatat tggctaaact attagaagcc gcaaaaaaac gtccggatga
    11041 tcagcgtttt attgtgggca cagttaattc taggtcaggt ctttttcctg ctaaagatat
    11101 ttgttatctg gatatgtggg gccctaaaaa gaattatcat gtgccgcgtt tccaccactc
    11161 aaacggcttc catgtagtcg ctctaaccat ccgcaactgc caggaggctt ttccttattt
    11221 atttcccgcc actccgggcc acctgataaa tgtatccaag gtagccggat atgacgaaca
    11281 tagttttggc gcaatggtaa aatttgaagg gacggattat acttgcccta tctccaatcc
    11341 aaaacttaag gctctaaaaa aatatctcaa aaacaaataa acccggccta tggtcgggtt
    11401 tatttaacat attttatttt tggtgtcaag atcaatctac cctaggatag cgcaaatcga
    11461 ttcgacatta gacgacattg tttgcatata tgtcatgtta cgatgctgat ataaaaggtt
    11521 aagacgttgt aaaaaatggc atttgtattt ataatgagaa catgcgtttg ccttttaggg
    11581 ataaaggagg tacttaagaa tcattattat gcaggtaaat aaataaaaag cggagtgtgg
    11641 gacatatgca aaaacatatt attgaggtgc agaaagaatt gagagacgat gatattgaaa
    11701 agttcgtttg tgctatgcta attattaggt ctattaaacc tccagtaagt attgaactga
    11761 taatgccgac gaaaaaaaag ctgcttgaag taagcagctt attcatgggg caataatggg
    11821 gcagatattt agagtctgtt tgataatata gactaagata tacatagata gaaaaagcaa
    11881 ttttgcttaa tcgcagccat ttgagtaatc aagaagccat atgaatatgt cgcaaatcag
    11941 ccttccaagc tgatagcgtg ggttcgattc ccatcacccg cttactgttt taagaagttc
    12001 ggaacccttg tgacacaagg ttttttgttt tgtttggagc tagataaata cattatagct
    12061 ggggtgccga cgggggtatc gcggcttttt gcgttcttac gaactatttt tacattgctg
    12121 cacaaaaata aaatataaaa tatttagctt aaatgctata aataaacaga taaaaagaac
    12181 tatttaccaa ttactaaaaa ataagtatag tcgcattgtc gggatttaac ttaaaaaggg
    12241 atggtgtagc tgcaatgagg aaaatttctt ttctgttttt agcattaact ttgatgctgt
    12301 ttactttttc agcaagttct acgttcgccg ctgctgattt tccaaatacg tcgacgaatg
    12361 gaatgactgg ttttgccgga caagctaaaa gtgaaaatgg agctactaag cctgccacaa
    12421 cggggggaaa aggcggtcag atcatctata tcaataatct aaacgatttg aaaaaccagt
    12481 taggggattc aactcctaaa attctggtaa tcgaaaaaaa tatttctgcc tcctctaaaa
    12541 ccgtggtcaa cattggttcc aacaaatcac tcattggttc ttatgctcaa aacaagctgg
    12601 ttaacattca tttgaaaaca acgaataatt caggaaatgt gatctttcaa aatttaactt
    12661 ttgagcacag tgccaacatt aatggtaacg atgacatcca actttatctc actgcaggta
    12721 caaattattg gattgatcat gttacatttg caggtcacaa ttataatgcg aatggctcgg
    12781 atctggacaa acttttgtac ataggtcaat cggctgatta tgtaaccatt agtaactcca
    12841 aatttgctaa tcataaatat ggtctcattt tgggataccc tgatgatggt aataaaaatt
    12901 atgatggcat gccccatatc acgatcgcca ataattactt tgaaaactta cttgtacgtg
    12961 gcccaggact tatgagatat ggatatttcc atgttaaaaa taattatatt aataatttcc
    13021 agcttgctta caccattgct acgaatgcaa gaatctattc tgagtacaac tactttggaa
    13081 aaggtagtga aaagggcggt attcttgatg ataaagccaa tggcgagttt aaagatgtgg
    13141 ggagttttcc cgccatcaac aaccaaaaat cgcgtgtaac cagctggaat ccaagcaaaa
    13201 actatagcta tcaggttcag actcctgaat atactaaaga gtttgtaacg aaatatgcag
    13261 gttcgtccaa tacaactttg gtatttggaa aataacgcgg gttatttgca aatgtgttgt
    13321 gatctgctat actgactgca agtaagtatc ccatgaaaag gaaggtaacc atacgtccga
    13381 tgaagtaagc acactgattt tcccacttaa ctgcacagtt actggcaggc ggctgtaagc
    13441 tgcaacggga gaagtgtgtc tgaaaatgaa tgtagggatg tatgcgttta ttccgaaacg
    13501 ggatttggct tattcgttta cggtgttatt tttcataagc gtatgttctg aaacgattca
    13561 taacagtcat tctatattcc ttgtatgcaa gccgcagcct tctgcggctt tttttattgc
    13621 ttccgggatc aaaaaaccgg actgggaaag gatgatcggt atgagaacga ttttgcgtat
    13681 tcgcaatgta gtcaaggatt ggagcgggac atctttattt gagaatgtgt cgttggatgt
    13741 gatggaagga gaacggctcg cactgtttgg aagaaatgga gcaggtaaaa cgacactatt
    13801 gcgaatattg ctgggggatg aagcgccaac ctctggtcaa gtagagcatg atttgccact
    13861 ggaagagcgg ggctggctga agcagcagga tacggtggct tggtctcgaa ccgcactgga
    13921 ggccgcacag caggccagcc ctcgtcattg gcgtctcaag caagcgttgg gacagctgga
    13981 agctgaccta gccgatgctg gggaggatat ggagcatcat ctggagcgtt acggcgaact
    14041 gatggatgaa tacgaacgcc tgcaaggctt tgcctgggag tctgaggtgg aaaaggcgct
    14101 cactcgaatg ggaatgcctg ttcagacgtg gtccattgct tatggtgacc ttagtggcgg
    14161 acagaagacg agagtgcgat tagccggact catggtcagg cagccgaagc tgctggtgct
    14221 ggatgagccg accaatcatt tggatgccga aagcttgctt tggctggagc agtggctgtc
    14281 cacgtatccg ggaacactgc tgtttgtatc gcatgacaga gcctttttgg atcgggtggc
    14341 tacgagtata gttgagctca cttcgacagg tattgggcgc tataaaggcg gctataagga
    14401 atataaagcg caaaaggagc gagaactgcg agagcaggaa gccagctatc ggaagcagga
    14461 gctcgcgaaa caggcgctgg aggaaacgat tcgaaattac agggaatggt ttcatcaggc
    14521 acatcgtggc gcatccaagg ttgagatggc cgtcacgcag agcttttata aggccaaagc
    14581 taaaaaaaat atttcccgtt atcatgcgaa ggagaaggaa ctggagcgac tggaggccaa
    14641 tagagtagag caaccgcgtg aggctgcgtc tttgcacatg aaattaagtg acagcgggtt
    14701 tcaggcaaaa tatttgctgc gtgctgagca ggttgacttt agctacgacg accgtatcat
    14761 tgtgaaaaat ctaaatctga tcgttgcacg tggagaccgt ctggctgttc ggggacccaa
    14821 tggaattggt aaaaccacgc tgcttcggtt attaacaggt caactggagc cgcagacagg
    14881 aaaaatcaca gccaacccac agttgaacat cggatatttt tcacaggagc tggagcagct
    14941 cccagaggat caaacgttgc tagacagtct gcttgcgctc ccgacgatga cgcaaacaga
    15001 agcgagaacg gtgttgggct gctttctttt tgcgaaagag gacgtgttta aaaagatcgg
    15061 gacactcagt atgggagaaa aatgcagggt agcttttctg cgtctgtact ttagtggagc
    15121 caatctgctg gtgctggatg aaccgacgaa ttattttgac attgaaaccc gtgaaattgt
    15181 agaggattct ttgcgtaact atgatggagc cctggtgctc gtctcacatg atcgggagct
    15241 ggtgaggtgc acggcaactc ggttacttga tatgaagccg gggggcggat atgaaatcta
    15301 tgagggaaca gccgacgaaa agcaagaaga tgagcggagc cgtcaacggg agccagaaga
    15361 ccaggagcgg cgtgaggaac ggcttcgatt acaattgcgt cttacagagt tgatgggaat
    15421 gacgggcacg aatgacgaaa atgagaagtt gttgagcgaa attaggcgca ttcgtgcaaa
    15481 tctggagcgg ttggatgatc tcgatatcta aaggaatgaa acgtatgccc tgcttgccaa
    15541 agcgcggtag tttgcatata ataatgaaca atagttcgaa tttttgaaaa tgtcttgatg
    15601 gagaagagta gacagtgtcc gattgaacag ggaggaagcg ccgtaggatt gagagcgttt
    15661 ctgcaaatac tgggctgttg aagttcgctc cggagcagtt ccttgaacct caggcgccat
    15721 gtaaatggcg aatgtgcaag taggggatac cggttcacga ccgttacaac gtgcagagcg
    15781 agacgatgat gcacagcatg aacaatcacc tgtaactagt tgccgtaagg cagaacgccg
    15841 ggtgagctga gcttattgtc taacgagggt ggtaccacgg tcttttcgtc ccttaccggg
    15901 agaaaagacc tttttttgtt gtctgaaaag ctggatatga agaaagggga ctgaacaggc
    15961 gatgagcgaa accatccaaa tgaaggaaca tttgctggcc ttgaaggaag aagcactgga
    16021 agtattggag aaggtggcaa cacccaagga gctggctgat ttacgggtca aatattcggg
    16081 gaaaaagggc gcattgactg aaatcttgcg cggtatgggc aagctgagcg cggaagagcg
    16141 tccggttgtt ggacaggtag ccaatgaggt gcgcgaggcg attgaagaag tcgttaaccg
    16201 taagcaggac gagttcacga aagcagaaac gaatgagcgt ttgcaagcgg aaaagatcga
    16261 cgttacgctg cctggacgcg cgttgccgca aggtggactg cacccgctca acaaagtgat
    16321 tgagcaaatc gaggatattt ttacaggtat gggctatcga gtggctgaag gtccacaggc
    16381 agagacggat tattataact tcgaagcatt gaacctgcct aaaaatcacc cagcacggga
    16441 tatgcaggat tcattttacc tgaccgagga tctgttgatg cgtacccata cgtcaccggt
    16501 tcagattcgt gcaatggaag cgatgaaggg cgaaacgcct attaaggtta tctgtccggg
    16561 tacggtattc cgacgtgatg atgacgatgc aacgcattct tttcaattcc accaaattga
    16621 agggcttgtc attggaaaag acattcgtat gagtgatttg aaaggaacct tacttcaatt
    16681 tgcacgcgaa atgttcggag aatcgaccga aatccgttta cgtccaagct tctttccgtt
    16741 cacagagccg agcgctgaag tagacgtgac ttttgtgaag aaaaatggcg agcgtgtatg
    16801 gattgaaatt ttaggctgtg gtatggtcca tccgaaagtg ctggagatgg gcggttttga
    16861 tcccgaggtg tacagcggct ttgcattcgg tatgggtgta gagcggattg ctatattgaa
    16921 atacggtatc gacgatattc gccattttta taacagtgac ctgtcgttcc tgaaacagtt
    16981 tgcgcgtcaa taaacaacta tatcaaggga agtgaaccca tatgaaagta tcattcgagt
    17041 ggctgtccga ttatgtatcg ctggatcagg taagcgcgga ggatctagca gagaaaatca
    17101 cccgttcggg catagaaatt gatgaggtcg agcagcgcaa tcaaggaatt actggtgtcg
    17161 ttgtcggcta tgttaaaagc aaggaaaagc atccagatgc tgataagctg aatgtatgta
    17221 ttgtcgatgc aggtcaagag gaagatctgc aaatcgtgtg tggtgctaaa aacgtggatg
    17281 caggtcaaaa ggttcctgtt gcagttgtag gtgcaaagtt gccgggagat ttccacatta
    17341 aaaaggccaa gctacgtggt gttgtatcca tgggcatgat ctgctcggcc aaagaactag
    17401 gcatgaatga caagctgctt ccaaaggaat tgcaagaagg tattttggtg ctgcctgagg
    17461 atgctgaaat tggtatgcca attacgaagc tgttggcgct ggatgatcag gtgctggatt
    17521 ttgatctgac acccaaccgt tcggattgcc tgagcatgca cggagcagca tatgaagtga
    17581 gtgcgattct gggacgtgac atttcgctgg ctgacccggc taaggatctg gtggaaatta
    17641 gcgatgcagc ggcagatcat ctgtctgtga aggtagatac tcctgaactg tgtacgcact
    17701 acgcggcccg ttatatcaca ggtgtaaaag taggggcttc cccgttatgg attcaaaacc
    17761 gtctgatggc ggcaggtgtt cgtccgatca acaacatcgt agatattacg aactacgtca
    17821 tgctggaata cggtcagcca ttgcatgctt ttgatgcgga taagctggaa aatggaaata
    17881 ttgaagttcg actcgctcgt gcaggcgaaa cattgattac acttgacgat caggagcgta
    17941 agctggagcc gcatatgctg ctgattacag acggtgtgaa acccattgca ttggcaggcg
    18001 tgatgggtgg agccaactcc gaggttacgg atgcgacggt cagcattgcg ctggaatctg
    18061 cgaagtttga cggcggtaca gttcgcaaaa cgtctcgtca acttggactg cgttcagaag
    18121 caagtctgcg ttttgaaaaa gagattgatc caggagctgt tgtgcctgct gtgaatcgtg
    18181 cagctgcgct gattcagcgt tatgcgggag gcactgtaca ccagggcatc gtagaatcag
    18241 cgtctgcaaa agctgaaaat cgcattatca agctgtcgct agataaaata aaccgatatt
    18301 tgggaaccga actgtcgctg cttgaggtga aaacgatttt cggtagactt catttcggat
    18361 gtggcgacgc agagcaaggg gtactggaag ttcaagttcc tacacgccgt ggagatatta
    18421 ctattgacgt ggacttaatc gaagaggtag ctcgtctgta tggttacgac aatatcccga
    18481 ccacgccgat tgaaggtcct acaactccgg gagctttgac agcatcgcaa tcattgcgcc
    18541 gctccctgcg cagattgctg gctcatggtg gttggcagga gacgatcagt tactcttttg
    18601 tacatccgca aagtacgggg ttatttaatg ccctgacaga aggtagccat ccggtacgtt
    18661 tggctatgcc tatgagcgaa gatcgtagtg ttttgcgtac gagtatcatt ccacagatgc
    18721 tggatacagc ggtgtacaac atgaatcgca agcaagacaa tctggcgatt tttgagatgg
    18781 gaacggtatt ttatacagag gaacaaacat taacccgtca gccgcaggaa attcaagtgc
    18841 ttagtctact gctgactggg gtacgccgtg aaaaacaatg gaatattggt gctgaaaagg
    18901 ttgatttctt tgatattaaa ggcgcgcttg aaacggtgtt tgactatttc ggattgagtg
    18961 ccagcattcg ttatgtggct gaccaaccac aaagctacca tccgggccgt tccgcttcgg
    19021 tatggctgga tgtgaatgga aactctcaac ggatcggtac cattgggcag attcatccgg
    19081 agcttcaaca atcttatggg ctgaacgata cgtatgtagc agaaatcgcg ttgcaacagg
    19141 tcgttgaaca cgccaactct catattcagt tcagagagct ggctcgcttc ccatccgtgg
    19201 aacgtgacat tgccctcgtg gtaaataaag acgttgaggc aggtgaactg cttcgtgtta
    19261 ttcacgctgc aggcggagag ctgttgcagg atgcccgagt atttgatgta tttacaggca
    19321 gtaagcttgg tgaagataag aagagcgtag ctatctctct gacctatcgt cattgggaac
    19381 atacgttgac ggatgaagag atcaatgcgg cccatactcc tgtcgttacg tctctggaac
    19441 aaacttttgg agcggaattg agaaagtagc aggaaatgcg ggaagccgta tcgaatctta
    19501 gtgacagagg ttcgatacgg ctttttggcc tatcatcata gaagctctct tactctgata
    19561 tttacccgct gcggggaagc cggactaata aggttgaacg cttcacggaa ggcgggttac
    19621 catagtaccg gacacacctt agaatcaaca tacagtagta ttgaaggagg gcataattgt
    19681 gactacacca gatcgtactc gcgtcactgt agagatctac ggtacttctt ataaactcgt
    19741 cggcagcaat accgattata tgaagcaggt tgccaattac gtggatgagc gcatgcacag
    19801 catttctcaa gctcattcgc gtctggatat gccccgaatt gccgtgctgg ctgcggttca
    19861 tatggcagaa gaagctgtac aaatccagga aattcagagt catatgaacc gcttagcagc
    19921 ggaacgagca gagctccgag gagatctggc gcaactccag acggctctag gggaacagca
    19981 gcaaaaaaat acagatcttc atcaatctct tgttcaacta aaggaagaaa aggaagcaac
    20041 gcagaagaag ctgatggaaa ccgaatctgt atcagccaaa gagattgccc aattgaagac
    20101 aaagctggaa cagcaggaga aaaaagcggc tgaacttgaa aatggacaaa aacaagctaa
    20161 acgtgaattg gaggagtctc gtcaagaagc ttctcgcaag ctgaaagagc agcaggaggc
    20221 ggctaatgcc cgtatccggc aaatagaaga gcagatgaag aaggaagtag ctgaagcggc
    20281 taaacaggct gaaaccaagc tgtcagctgc agagaagact catcaggagc aaaagcgtac
    20341 agaactggac aagctgcgat ctgctttgca gcaagagcat agtaagaaag taagcgaatg
    20401 gcagaccaag tgctccgggc tgaatgagca gctggagcag gaacgtaaac aggctgaatt
    20461 ggcgttgaat gaagaaaagc tccagcatca ggaagcgcag aaacgagctg atgaagctgc
    20521 actgg
//
