LOCUS       NZ_POVS01000008        24339 bp    DNA     linear   CON 15-SEP-2024
DEFINITION  Paenibacillus sp. F4 F4_contig_7, whole genome shotgun sequence.
ACCESSION   NZ_POVS01000008
VERSION     NZ_POVS01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. F4
  ORGANISM  Paenibacillus sp. F4
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 215912)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Genome sequencing and comparative analysis of polymyxin-producing
            Paenibacillus strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 215912)
  AUTHORS   Jeong,H., Park,S.-Y., Choi,S.-K., Ryu,C.-M. and Park,S.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2018) Infectious Disease Research Center, Korea
            Research Institute of Bioscience and Biotechnology (KRIBB), 125
            Gwahak-ro, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-JAN-2018
            Assembly Method                   :: CLC Genomics Workbench v. 11.0
            Assembly Name                     :: F4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 524.4x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002894905.1-RS_2024_09_15
            Annotation Date                   :: 09/15/2024 04:37:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,419
            CDSs (total)                      :: 5,299
            Genes (coding)                    :: 5,203
            CDSs (with protein)               :: 5,203
            Genes (RNA)                       :: 120
            rRNAs                             :: 10, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 102
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 42 of 96
            Pseudo Genes (incomplete)         :: 67 of 96
            Pseudo Genes (internal stop)      :: 14 of 96
            Pseudo Genes (multiple problems)  :: 22 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:44:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 24339
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            POVS01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24339
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..24339
                     /SMILES="NC(CS)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24339
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<2:4339](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <3..4339
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            <1..4339
                     /locus_tag="C1T21_RS05815"
                     /old_locus_tag="C1T21_05815"
     CDS             <3..4339
                     /NRPS_PKS="Domain: PCP (80-148). E-value: 1.6e-24. Score:
                     77.8. Matches aSDomain: nrpspksdomains_C1T21_RS05815_PCP.1"
                     /NRPS_PKS="Domain: Heterocyclization (168-466). E-value:
                     3.3e-92. Score: 301.0. Matches aSDomain:
                     nrpspksdomains_C1T21_RS05815_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (629-1028). E-value:
                     2.7e-99. Score: 324.5. Matches aSDomain:
                     nrpspksdomains_C1T21_RS05815_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1137-1204). E-value: 2.1e-14.
                     Score: 45.5. Matches aSDomain:
                     nrpspksdomains_C1T21_RS05815_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (1225-1428). E-value:
                     1.6e-27. Score: 89.4. Matches aSDomain:
                     nrpspksdomains_C1T21_RS05815_Thioesterase.1"
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="C1T21_RS05815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05815"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_146032478.1"
                     /sec_met_domain="PP-binding (E-value: 1.8e-17, bitscore:
                     57.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.5e-50, bitscore:
                     164.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-105, bitscore:
                     347.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 6.8e-22, bitscore:
                     72.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="DHRNHVFLCAYYVPDEEEVTPEELRIYLQRELPNYMVPSHYMELE
                     KLPLSPNGKVNRRELPIPDVEQQMDSKYEEARNETEQKLTEIWKEVLGVERIGIHDHFF
                     ELGGNSILMVQIRTRISREMGIDLNLRDFLQHYTIAKLSERIKEGVDTQEAIVYPELIP
                     DPEHMYEPFPLTDVQMAYLMGREDHFEMGGVSTHVYIELETSLDMDRFNRALQKVIERH
                     AMLRTIILPSGQQQILDYVPEYHIEVIPIQDLSKEAQEKKILMERERMSHYIFKTDQWP
                     LFEYKAYQCSAERFYLFIGYDMLITDGASFQFIHQEIMKFYHDPDLDLEGVDITFRDYM
                     MAYTGFKSSEIYKRDRQYWTDKLECFPDPPALPYVSSPSLIVQPRFKRVTKHCNRELYE
                     KLKQVSQKNHVTPTAVLCTVFAKVLSYWSNQSQLALNCTIFNRYPFHKDVYKMIGDFTS
                     VMLLDITLEGGKSFWEQTESVQNVLMEALEHRHYDGIQFIREIIRQRGAETHKAAMPIV
                     FTSMLLDTGKGTDDSVYYMGDVKTAVSQTSQVFLDYQVLEVDGGLTITWDYVEQLFDSE
                     FIKTMFDQYFMLLEFSLSSDAGNRFPWGHENHLLISAFNHTCEEIPRTTLHSLFEQQVV
                     RWPEAIAVIYKNSHITYQELNERSNRVARYLQEYGVCRGDFISVLANRSIETIVNIIGI
                     LKAGAAYVPIDPDYPEERREYIRDHSGCKLMLEPDLYVKKELAVYSGEALQVEHDPDDV
                     AYVIYTSGSTGQPKGVIVTHGAVANTVQDINRKFNVNEQDRIIGLSSMCFDLSVYDLFG
                     ALAVGAALVLIDDQRNITEVAKTLEEHKITIWNSVPAIMDLMLNHVLGEEEESGYYWDG
                     KYRSSGARKKNTSLRLVILSGDWIPLSLPDKIRRQYFHANVVSMGGATEASIWSIYYPV
                     YEVHEDWASIPYGMPLANQTYYVLNYDQELCPVGVKGELFIGGVGLAKGYLHEEEKTAF
                     SFFNHPNFGRLYRTGDQGILNSKGYIEFLGRNDQQVKIRGYRVELGEIENQILQIIGVK
                     EAVVLYTPDSKGNKVLCAYIVAQPSLSIQDIKEGISRALPNYMVPTHFICLEQIPLTPN
                     GKLDRKALPEPSAKTIFQKKYEAPVTEMECLMVRIWEEILEYSSISVDDSLFELGVDST
                     SVIKFVARLATGNGIELPIRQIFVTPTIRELASLVSSSETQISDLSNERMLFNSQGERD
                     RNIFCFPPVVALGVVYQRLAEFLGSYRLYSFNFLEIEQDRLIAEYIRLIKEVQPEGPYV
                     FLGISAGGNLAFEITKALEKQGDKVGQLILLDSFYITEINSERLTTEESRKYAKETVDL
                     MLKKYPQLQSEGEFFHLHVGEKIQRYYAYLDNLMNSGQVAAHIHVIKSLQSQSKHIRGD
                     IRMWEHSTIGEYSICDGYGDHESMLDATFVEQNAELILSILEK"
     aSDomain        245..448
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS05815_PCP.1"
                     /evalue="1.60E-24"
                     /label="C1T21_RS05815_PCP.1"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="148"
                     /protein_start="80"
                     /score="77.8"
                     /tool="antismash"
                     /translation="EQKLTEIWKEVLGVERIGIHDHFFELGGNSILMVQIRTRISREMG
                     IDLNLRDFLQHYTIAKLSERIKE"
     aSDomain        509..1402
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS05815_Heterocyclization.
                     1"
                     /evalue="3.30E-92"
                     /label="C1T21_RS05815_Heterocyclization.1"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="466"
                     /protein_start="168"
                     /score="301.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DMLITDG"
                     /tool="antismash"
                     /translation="YEPFPLTDVQMAYLMGREDHFEMGGVSTHVYIELETSLDMDRFNR
                     ALQKVIERHAMLRTIILPSGQQQILDYVPEYHIEVIPIQDLSKEAQEKKILMERERMSH
                     YIFKTDQWPLFEYKAYQCSAERFYLFIGYDMLITDGASFQFIHQEIMKFYHDPDLDLEG
                     VDITFRDYMMAYTGFKSSEIYKRDRQYWTDKLECFPDPPALPYVSSPSLIVQPRFKRVT
                     KHCNRELYEKLKQVSQKNHVTPTAVLCTVFAKVLSYWSNQSQLALNCTIFNRYPFHKDV
                     YKMIGDFTSVMLLDITL"
     aSModule        509..4288
                     /complete
                     /domains="nrpspksdomains_C1T21_RS05815_Heterocyclization.1"
                     /domains="nrpspksdomains_C1T21_RS05815_AMP-binding.1"
                     /domains="nrpspksdomains_C1T21_RS05815_PCP.2"
                     /domains="nrpspksdomains_C1T21_RS05815_Thioesterase.1"
                     /final_module
                     /locus_tags="C1T21_RS05815"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       596..688
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0001"
                     /evalue="8.60E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="228"
                     /protein_start="197"
                     /score="31.0"
                     /tool="antismash"
                     /translation="VYIELETSLDMDRFNRALQKVIERHAMLRTI"
     CDS_motif       890..934
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0002"
                     /evalue="9.20E-04"
                     /label="Cy3"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="310"
                     /protein_start="295"
                     /score="12.6"
                     /tool="antismash"
                     /translation="YLFIGYDMLITDGAS"
     CDS_motif       1229..1288
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0003"
                     /evalue="5.10E-09"
                     /label="Cy4"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="428"
                     /protein_start="408"
                     /score="28.7"
                     /tool="antismash"
                     /translation="HVTPTAVLCTVFAKVLSYWS"
     CDS_motif       1340..1396
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0004"
                     /evalue="9.40E-07"
                     /label="Cy5"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="464"
                     /protein_start="445"
                     /score="21.1"
                     /tool="antismash"
                     /translation="HKDVYKMIGDFTSVMLLDI"
     CDS_motif       1460..1504
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0005"
                     /evalue="6.10E-04"
                     /label="afterCy5"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="500"
                     /protein_start="485"
                     /score="12.7"
                     /tool="antismash"
                     /translation="ALEHRHYDGIQFIRE"
     CDS_motif       1631..1675
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0006"
                     /evalue="8.00E-04"
                     /label="Cy7"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="557"
                     /protein_start="542"
                     /score="12.6"
                     /tool="antismash"
                     /translation="VSQTSQVFLDYQVLE"
     aSDomain        1892..3088
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS05815_AMP-binding.1"
                     /evalue="2.70E-99"
                     /label="C1T21_RS05815_AMP-binding.1"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="1028"
                     /protein_start="629"
                     /score="324.5"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FEQQVVRWPEAIAVIYKNSHITYQELNERSNRVARYLQEYGVCRG
                     DFISVLANRSIETIVNIIGILKAGAAYVPIDPDYPEERREYIRDHSGCKLMLEPDLYVK
                     KELAVYSGEALQVEHDPDDVAYVIYTSGSTGQPKGVIVTHGAVANTVQDINRKFNVNEQ
                     DRIIGLSSMCFDLSVYDLFGALAVGAALVLIDDQRNITEVAKTLEEHKITIWNSVPAIM
                     DLMLNHVLGEEEESGYYWDGKYRSSGARKKNTSLRLVILSGDWIPLSLPDKIRRQYFHA
                     NVVSMGGATEASIWSIYYPVYEVHEDWASIPYGMPLANQTYYVLNYDQELCPVGVKGEL
                     FIGGVGLAKGYLHEEEKTAFSFFNHPNFGRLYRTGDQGILNSKGYIEFLGRNDQQVKIR
                     "
     CDS_motif       2081..2119
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0007"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="705"
                     /protein_start="692"
                     /score="18.4"
                     /tool="antismash"
                     /translation="GILKAGAAYVPID"
     CDS_motif       2264..2323
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0008"
                     /evalue="1.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="773"
                     /protein_start="753"
                     /score="32.7"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVIVTH"
     CDS_motif       2438..2476
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0009"
                     /evalue="9.10E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="824"
                     /protein_start="811"
                     /score="0.8"
                     /tool="antismash"
                     /translation="GALAVGAALVLID"
     CDS_motif       2888..2977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0010"
                     /evalue="6.00E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="991"
                     /protein_start="961"
                     /score="37.8"
                     /tool="antismash"
                     /translation="PVGVKGELFIGGVGLAKGYLHEEEKTAFSF"
     CDS_motif       3053..3118
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0011"
                     /evalue="3.40E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="1038"
                     /protein_start="1016"
                     /score="38.2"
                     /tool="antismash"
                     /translation="FLGRNDQQVKIRGYRVELGEIE"
     CDS_motif       3152..3187
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0012"
                     /evalue="4.70E+00"
                     /label="NRPS-A_a3"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="1061"
                     /protein_start="1049"
                     /score="1.0"
                     /tool="antismash"
                     /translation="AVVLYTPDSKGN"
     aSDomain        3416..3616
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS05815_PCP.2"
                     /evalue="2.10E-14"
                     /label="C1T21_RS05815_PCP.2"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="1204"
                     /protein_start="1137"
                     /score="45.5"
                     /tool="antismash"
                     /translation="LMVRIWEEILEYSSISVDDSLFELGVDSTSVIKFVARLATGNGIE
                     LPIRQIFVTPTIRELASLVSSS"
     aSDomain        3680..4288
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1T21_RS05815_Thioesterase.1"
                     /evalue="1.60E-27"
                     /label="C1T21_RS05815_Thioesterase.1"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="1428"
                     /protein_start="1225"
                     /score="89.4"
                     /tool="antismash"
                     /translation="RNIFCFPPVVALGVVYQRLAEFLGSYRLYSFNFLEIEQDRLIAEY
                     IRLIKEVQPEGPYVFLGISAGGNLAFEITKALEKQGDKVGQLILLDSFYITEINSERLT
                     TEESRKYAKETVDLMLKKYPQLQSEGEFFHLHVGEKIQRYYAYLDNLMNSGQVAAHIHV
                     IKSLQSQSKHIRGDIRMWEHSTIGEYSICDGYGDHESMLD"
     CDS_motif       3836..3910
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1T21_RS05815_0013"
                     /evalue="7.90E-10"
                     /label="NRPS-te1"
                     /locus_tag="C1T21_RS05815"
                     /protein_end="1302"
                     /protein_start="1277"
                     /score="31.1"
                     /tool="antismash"
                     /translation="QPEGPYVFLGISAGGNLAFEITKAL"
     gene            complement(4419..5738)
                     /locus_tag="C1T21_RS05820"
                     /old_locus_tag="C1T21_05820"
     CDS             complement(4419..5738)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369945.1"
                     /locus_tag="C1T21_RS05820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05820"
                     /product="Nramp family divalent metal transporter"
                     /protein_id="WP_103047577.1"
                     /transl_table=11
                     /translation="MKNTKGNFAEIASLSEVNRSLIVPKDGTWFRKFLAFAGPGYMVAV
                     GYMDPGNWATDIAGGSKFGYTLLSVILISNLMAILLQALSGKLGIATGKDLAQMCRDAY
                     SRPVAIGLWLLCEIAIAAMDLAEVIGSAIALKLLFGLPLLYGVIITAFDVMLILLLQNK
                     GFRALETLVIVLMATIAGCFGINLILAQPEWGGVLGGFVPDSQILTNPSMLYIAIGIMG
                     ATVMPHNLYLHSSIVQTRKFEQTSAGKREAITFATWDSSIALMFALFINAAILIVAAAV
                     FHTAGRTDVAEISDAYYLLSPLLGTTLASILFGVALLASGQNSTVTGTLAGQIVMEGFL
                     NLRLSPWLRRLVTRLIAIIPAVIVTAIAGEKGAEELLVLSQVILSIQLPFAIIPLLLFT
                     SDKKIMGEFANKMWQKVLTWIVTAIIIILNVVLIVQTISG"
     gene            complement(6046..6276)
                     /locus_tag="C1T21_RS27765"
     CDS             complement(6046..6276)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016925.5"
                     /locus_tag="C1T21_RS27765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="manganese catalase family protein"
                     /protein_id="WP_258012374.1"
                     /transl_table=11
                     /translation="MKAYSHHFIVSAQTSMTDNPVAREIVGYLLVRGEVHVMAYVKALE
                     KLTGIEMTKMLPIPNLENKAFSETRKFEEKD"
     gene            6491..6910
                     /locus_tag="C1T21_RS05830"
                     /old_locus_tag="C1T21_05830"
     CDS             6491..6910
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369947.1"
                     /locus_tag="C1T21_RS05830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05830"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_013309264.1"
                     /transl_table=11
                     /translation="MEALYTASATVHGGRDGSVASSDGVLKHKLSTPKELGGAGGEATN
                     PEQLFAAGYGACYESALANVARKAKVKVDNVEVTSHVSIGKDPSDGGFQLAVRLDVKIP
                     GIERAQAEDLARQAHDFCPYSKATRGNIDVELNVI"
     gene            7034..7360
                     /locus_tag="C1T21_RS05835"
                     /old_locus_tag="C1T21_05835"
     CDS             7034..7360
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820695.1"
                     /locus_tag="C1T21_RS05835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05835"
                     /product="hypothetical protein"
                     /protein_id="WP_025722703.1"
                     /transl_table=11
                     /translation="MILVIRYETNLKNTGDMMSYRPNIVNFTLAGSNEKEGLYEFKMSL
                     ADGTECRVFSQRNPEWTLTNISRLLTTPCPVCHKDFICKCMDKFHEEFLEQINTKQLFE
                     KALS"
     gene            7490..7915
                     /locus_tag="C1T21_RS05840"
                     /old_locus_tag="C1T21_05840"
     CDS             7490..7915
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014599553.1"
                     /locus_tag="C1T21_RS05840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05840"
                     /product="thiol-disulfide oxidoreductase DCC family
                     protein"
                     /protein_id="WP_103047578.1"
                     /transl_table=11
                     /translation="MNQSDHARSDHSIVLVDGVCHFCQGAVRFIIKRDPKGTFHFGSLQ
                     SEAGQELLRAGGLSTDQLDTFVLIEDGTYYTRSTAALRIVKRLRFPYPLAYVFILVPRF
                     VRNAVYNWVARNRYRWFGKDEEDQCQIPPPEIRQRFF"
     gene            complement(7924..8700)
                     /locus_tag="C1T21_RS05845"
                     /old_locus_tag="C1T21_05845"
     CDS             complement(7924..8700)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309267.1"
                     /locus_tag="C1T21_RS05845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05845"
                     /product="DUF3153 domain-containing protein"
                     /protein_id="WP_103047579.1"
                     /transl_table=11
                     /translation="MEPTGYSPYRNKCRQVRIRKILLIFMLVCCLLVLTSCARGDIHVD
                     VHLDQSVDMDATFSVNNQTLMMLDNPGLLDRLVKRIQSNNVDVQPLAEQGRKGYQIKGH
                     YQGDWSTNKKNPSQELNLPEGLEIKRAVSQHFFTTNIDLTMKLDLPRMLPEEAQGLSDK
                     FEQMNVFARKLLERQLDLNFSLSLPIQPATNNADRVSEDGKTLYWDIAPLESNELKLSV
                     NVPNVRHIVYVAVTSLILIVIAVILLIRRHRSKKET"
     gene            8936..9907
                     /locus_tag="C1T21_RS05850"
                     /old_locus_tag="C1T21_05850"
     CDS             8936..9907
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1252: cation ABC
                     transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820692.1"
                     /locus_tag="C1T21_RS05850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05850"
                     /product="metal ABC transporter solute-binding protein,
                     Zn/Mn family"
                     /protein_id="WP_103047580.1"
                     /transl_table=11
                     /translation="MNKQFKKALPRWVTTVGVLSLALVLATACTDAKKKEQGTAREAGQ
                     KIKATATIGMISDIVGKVGGNHVEVTGIMKSGVDPHLYKASQGDMRKLDQADVIFYNGL
                     HLEGKMQDILEKISKQKPVIPVSKNIAQDQLRAGSPEMGSEHDPHIWFNVQNWMSAVET
                     VRDELSALDAVHAEEYKANAEAYLTELRELDDYTREQIASIPEAQRVLVTAHDAFGYFG
                     DAYHIQVRGLQGMSTESEAGSQDVTKLRDYLVEHKIKAIFVESSVPRKAIDAVIQGAAQ
                     QGHTIRVGGELYSDAMGEEGTEDGTYIGMVKHNVNTIVKALK"
     gene            9922..10686
                     /locus_tag="C1T21_RS05855"
                     /old_locus_tag="C1T21_05855"
     CDS             9922..10686
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820691.1"
                     /locus_tag="C1T21_RS05855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05855"
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="WP_023987614.1"
                     /transl_table=11
                     /translation="MGHSPLVVRDLSVAYQKKPVLFDVSFEVPEGKLIGIIGPNGAGKS
                     TLIKAALGLIPKLRGEVLVYGKPYKQQLLKVGYVPQRESVDWDFPTNALDVVMMGRYGR
                     LGWFKRPGAADRQAAMESLDKVGMSKYADRQISQLSGGQQQRVFLARALAQDAQLYFMD
                     EPFVGVDAATEKAIISLLNDLKQQGKTVLVVHHDLSTVTDYFDQVMLLNGHLMAFGETT
                     DIFTEENLQRTYGGRLSILKTGPDSGTILGVR"
     gene            10692..11621
                     /locus_tag="C1T21_RS05860"
                     /old_locus_tag="C1T21_05860"
     CDS             10692..11621
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1245: ABC transporter
                     protein, integral membrane"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309270.1"
                     /locus_tag="C1T21_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05860"
                     /product="metal ABC transporter permease"
                     /protein_id="WP_069291389.1"
                     /transl_table=11
                     /translation="MTSLATLLTDPNMQWILLGCILLGLSSGVIGSFMYLRKQSLMGDA
                     LAHAALPGVCVAFMITGTKSVFGFMIGAAIAGIVATFAISALTRYSRIKSDSAIAAVLS
                     VFFGFGIMLLTEIQHSGAGNQSGLDKFLFGQAAAMVLSDVYTMAVISVVLIGICILFFK
                     EFKLLSFDPGFARGLGYPAGLLDKLLMLLIVIAVVAGIQAVGVIMMAALLITPAVSARY
                     WTEKLGVMVCLSGLFGAIAGLGGTLISSLGQNLPTGPLCVLCATVVFGMSLIFAPQRGM
                     ISKAIVRLNARKNLEQTVGTQPREERAL"
     gene            11618..12505
                     /locus_tag="C1T21_RS05865"
                     /old_locus_tag="C1T21_05865"
     CDS             11618..12505
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1245: ABC transporter
                     protein, integral membrane"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369955.1"
                     /locus_tag="C1T21_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05865"
                     /product="metal ABC transporter permease"
                     /protein_id="WP_103047581.1"
                     /transl_table=11
                     /translation="MSSFYVILTGMLVAGGCSIVGCFLVLRKMAMIGDAISHAVLPGIV
                     IAFLISGSRDSVWMMFGAAVLGLLTVYLIQLFQQSGLQSDAAIGVVFTTLFAIGVLLIS
                     VFASNAHLDMDHVLYGEIAYVPWNTFEIAGFDVGPRAVWITGAMFLINLLVIGGFFKQF
                     KITSFDPALAASLGIPVVFFHYLLMSLVSLTTVASFESVGAILVVGMLVVPPLTAYLLT
                     EKLSRMIVYSVGFGAISSVVGFYTASVLDASIAACMLCVSGVLLLLAFLFSPSHGVVWQ
                     KLFQQRGIVGEDSK"
     gene            12721..15048
                     /locus_tag="C1T21_RS05870"
                     /old_locus_tag="C1T21_05870"
     CDS             12721..15048
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820688.1"
                     /locus_tag="C1T21_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05870"
                     /product="histidine kinase"
                     /protein_id="WP_103047582.1"
                     /transl_table=11
                     /translation="MESFKRKSPEEILDSINKLHRGRLKIYMGAVSGSGKTYHMLQEGQ
                     SLQHEGIDVVICAVSTMQRPVTVEQVGTLERVPSIHWIKDGEEQKDLNVEALVARNPEV
                     VLVDHLAHHNRKDAPFPTRLEDIRYLLEQGISVITTVNVYELEGITEWVYQLTGFEAEY
                     TVPVDTLELADEIRLIDATPEMILERLAKGYMHTSNPEMFHRGNLGKLRELALRLVAED
                     VNDSLERHREELGLHGASGAAERILVPVQYHWNGSIYVRRGEQVAKRLGGDMLVVSFVS
                     SKRKLSKESAAFKRSIEQLADKIGSTFEEIPLFSRRRLPRQLIHYAVTHNVTRIVMGHS
                     RQTPWQELMKGSLVNGILKRMKNMDLLLIADRAEQEGERILPTMRQEEGDNDPYHRLSV
                     EEAQAEAAKILRGKLKVYIGAAPGVGKTYTMLREGNDLLESGIDVVIGLLETHGRAETL
                     AQVGSLEMISRQSIERHGAHLEEMDTEAILRRNPEVVLIDELAHTNVPGSLRTKRYEDV
                     LTILEQGISVISTMNVQHLESLNDAVEQITGIRVRETVPDHMMRLADEVQLVDVAPKSL
                     QQRMREGKIYDHAKVEQALSHFFKLGNLIALRELALRELADDVDERLESWDRHESLRGP
                     WRREEVIFVGVTLSENAERLIRRGFRIAFRLKAVWIVTYAHVGERIPERLNPRLEQLKL
                     LTHRLGGTFEIRLVSSRREIADILIAPVEGYSGTQLIVGQSSRSSRWGKAAVVPRILRQ
                     ARHMDVLIVADYDPDIKLEVDH"
     misc_feature    15165..15179
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     gene            15577..16734
                     /locus_tag="C1T21_RS05880"
                     /old_locus_tag="C1T21_05880"
     CDS             15577..16734
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426544.1"
                     /locus_tag="C1T21_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05880"
                     /product="hypothetical protein"
                     /protein_id="WP_103047584.1"
                     /transl_table=11
                     /translation="MVPVKVVLAVEGRDYIEPLLNYVHGSEYARRLRITAFSQPEAFHQ
                     YMMETSGMKRPDVVVGEAAFLNLWTDREAADIPCLVLHEGEQVDEYGQLLLKYQPLSEL
                     VGFILETARQRSNGRKSVNSREGGMIIGMVAASGGLGKTTAALNMSKQLGNEGYSVFYL
                     NLETVDSSSLFTGSGSASGAEGEGLSRLLYDLKAGGSEDTPLSMASYCIRRPEIQADTF
                     QPVYNRKELTDMTCDEAKELIRTVAESGQYDVVIVDGDSEKGDRAQAVLEASHKLIWLL
                     ADDLMSMHKCGLWLDVLETTQPEGLEDMICKTSFVVNRYMGTMINSLPRDFMELNGALP
                     YIPSWKQMQHRELLLSSPIYQREIRHLCHELLNVDSVTHPPAVWS"
     gene            16750..17997
                     /locus_tag="C1T21_RS05885"
                     /old_locus_tag="C1T21_05885"
     CDS             16750..17997
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369960.1"
                     /locus_tag="C1T21_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05885"
                     /product="CpaF family protein"
                     /protein_id="WP_103047585.1"
                     /transl_table=11
                     /translation="MNEERFKALRADIRNGLDVTSSVKDADLVRHIENRILHDVELVGL
                     TSREKHALVRKIFNSFRGLDVLQPLIDDPTVTEIMINSHREIFVERAGEVMQVPDQFES
                     RERLEDLIQTIVAGVNRIVNEASPIVDARLKDGSRVNIVLPPVALKGPTMTIRKFPERP
                     MTMDDLIQMGALDAETAAMLKDLVRSKYNIFISGGTGSGKTTFLNALSQFIPSSERIIT
                     IEDSAELQIVTVPNLVSMETRNANTEGKGEITIRDLIRSSLRMRPNRIVVGEVRGSEAL
                     DMLQAMNTGHDGSLSTGHANNIRDMVSRLETMVLGGAELPLGVVRQQISSAIDIFVHLS
                     RMRDKSRRVLEISEVIGFENGEVTLNPLYRFQERGESKGRIVGGLERCGEGLQHTLKLQ
                     MAGINPENWHRGGVSA"
     gene            17994..18785
                     /locus_tag="C1T21_RS05890"
                     /old_locus_tag="C1T21_05890"
     CDS             17994..18785
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429364.1"
                     /locus_tag="C1T21_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05890"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_103047586.1"
                     /transl_table=11
                     /translation="MKPGKTTAKQVSREVPSLPDYTVYTLSTVQKSLCIFFSGVLFAMI
                     GYLFYHQWILSLLCAAGAGVTPRYFRQFLLHRRRSALSIQFKQALYSLSSSLSAGRSVE
                     NGFREAVEDLRLLSPDGDHDLIFEFNIITACLEIGQPVEAALQDLARRAQMEDITNFAD
                     VFAACKRTGGDLVEVVRRASSVIGEKLEIQQEIGVMIAQKRFESRVMFAAPFLFVLFMT
                     MTAGDYMMPLYSGTGMILSTFCLLVLGGCLVWINHIMKIEV"
     gene            18792..19676
                     /locus_tag="C1T21_RS05895"
                     /old_locus_tag="C1T21_05895"
     CDS             18792..19676
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426547.1"
                     /locus_tag="C1T21_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05895"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_103047587.1"
                     /transl_table=11
                     /translation="MGVVMLVCLVMLVLQVGGWVVLNQMHGAKYAHFRHMKLEGLRLQR
                     LSVPFVHMIHASRATHRLPLLMFKLQRSVQKLYGMRNSGEKTMLFLAEMLGYGYMMAAG
                     GAIISLMLGGDATGLVLGLGLGILVPIALIKDLHGKVQKRDQQILMELPELLSKMMLLV
                     GAGETVQRALLHCVERKGADTEHPLYRELRQTVGEWESGYSFQQAFEHLSKRCGIQEMT
                     VFTTTVLLNMRRGGSDFVMALRELSQTLWGKRTSISRTRGEQASSKLVFPMALILLTVI
                     VLVGAPALMMMNM"
     gene            19690..19881
                     /locus_tag="C1T21_RS05900"
                     /old_locus_tag="C1T21_05900"
     CDS             19690..19881
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429366.1"
                     /locus_tag="C1T21_RS05900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05900"
                     /product="Flp1 family type IVb pilin"
                     /protein_id="WP_103047588.1"
                     /transl_table=11
                     /translation="MMTLVTGSIRKLYKGEDGLGTLEMILIIAILIAVAIIFKDQIKKI
                     VEGLLKKADKKSNDFMDS"
     gene            19881..20548
                     /locus_tag="C1T21_RS05905"
                     /old_locus_tag="C1T21_05905"
                     /pseudo=""
     CDS             19881..20548
                     /GO_process="GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686580.1"
                     /locus_tag="C1T21_RS05905"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05905"
                     /product="TadE family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLRKLAQKEDGSFSLEASLVFPILLLVIFVMLFFCLYIYQKSILV
                     QVAATASERAAYSWDNSFKDPRTGAFMQGQRDSLYWRLKDDVMLGALFGWTGANNQESV
                     QVPGGNGGGSLPAQKLSNAENNMPAGMQGQMTYENSMIHRKVITKLNKIVKVPLLNQFL
                     DQTDLQGEMSSGVVEPVEWIRTVELVRYYGAKLWAEDQVKR"
     gene            20589..22805
                     /locus_tag="C1T21_RS05910"
                     /old_locus_tag="C1T21_05910"
     CDS             20589..22805
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349411.1"
                     /locus_tag="C1T21_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05910"
                     /product="DUF5702 domain-containing protein"
                     /protein_id="WP_103047589.1"
                     /transl_table=11
                     /translation="MFGKGHNTKDGESGAVTVFLILILAVMFGFIAVFIDYARIAALHV
                     QTERLTHAAVRSVMSAYDPTLQQEYGLFAYGEGGGEQIMVKVLNDSARRTARADTLPLM
                     NMKLDSSSLQMERELGKYAIFNEQIREEMKYKAPVDFTFEVLEKLKPLSQNMKEASHTV
                     DLLKRLQKLYDRREAKLDDMLEKQRKAGAYMEEVRKRIIKQRGTYMPNQYIWDPLEVVA
                     DIAAQYKHYVHVYEDNKKSVDDVKIMQMEKYARRARAALDRLRQIMVQAGEEHDKLLLE
                     AKEPLNEAQQINEEMRKVIAQYKQRAANAGYDEVSAAPTSSGAGSNADPSVGSARQKAE
                     DLLIPDKEFEQWEAEIEKQRTSINTANNIITSMMRTLSFYTDPFLNADMLKQEVASTLK
                     EIDKYLNAYAWAGPANVLDGEAKMMDTRRGPDKERKKMEKEAKNKLKQAYRIIEVLSKG
                     KQSAEQFQNLERYYNESISFNQSTSSPSVSADLPYDTYDAVGASMDSMDGLYGSASNLL
                     TQLGDEFYQNEYALSYFHHVDFSRFGSLAGSGGNVGNAAQILGDQLEVNNQEVEYILYG
                     FHNPTGNLASAYGEIFAMRLAIRTMEGLVKNSSKGNPLVVLAAALLYGVEKAIEDMIML
                     AQKGDVPLSDFLKFRMTYKDHLRLFLMLHSNNERKMSRMLALIRLNTDVNPAERQTYAT
                     GEVRNGMRLWFLPGVMKMLGTASKEGESIKGSVYYVTKTAHFSY"
     gene            22774..23769
                     /locus_tag="C1T21_RS05915"
                     /old_locus_tag="C1T21_05915"
     CDS             22774..23769
                     /GO_process="GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686582.1"
                     /locus_tag="C1T21_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1T21_05915"
                     /product="TadE/TadG family type IV pilus assembly protein"
                     /protein_id="WP_103047590.1"
                     /transl_table=11
                     /translation="MSRKQRIFPINRCLRKVCGQKQCEQGSIVLEASLVLPMFLFFIIF
                     LIYMVQMTLVSTALQNTASEAVKQVSTKIYPVSLAVEAASAKIDTVREPMDELPRLSVS
                     EYASQFAAQLPPPIGDWVESAVQGGQKPMEELRGRFTEAALDPVLKPMLKPFMEESILE
                     YDRIHVTSIHVPALTGTKDPYFRVELSYELPMKVPFLYRSIVLQAAAEERLWIGDTGEG
                     TGTEEATADKDAQHSIQLLVKPEPAVKGVYNLIKAKVEPGKTANLSVLYKSGESTAQHL
                     GWTSANVDGIIEWNWFVGTNTTPGQWSFVIETEDGQRIEVPFTVEKPADG"
ORIGIN
        1 ggatcatcgc aatcacgtat ttctatgtgc gtactatgtt ccagatgagg aggaagtgac
       61 cccagaggag ctacgaatat atttacaacg ggaactgcca aattatatgg tgccgtcgca
      121 ttatatggaa cttgagaaac taccgttgtc tcctaatggc aaggtgaatc gaagagagct
      181 gccgatcccg gatgtggagc agcaaatgga ttcgaaatac gaagaagcac gtaatgaaac
      241 agagcagaaa ctgacggaaa tatggaaaga ggtattgggc gtcgaacgaa taggaatcca
      301 tgatcatttc tttgaactag gtggaaattc gattctgatg gtgcaaatcc gaaccagaat
      361 aagcagggaa atgggaatcg atttgaatct acgagacttc ctgcagcatt atactatagc
      421 gaagctgtcg gaacggatca aggaaggtgt agatacacaa gaggccatcg tgtatccgga
      481 gttaatacct gatccggaac atatgtatga accgtttccg ttaacggatg tgcagatggc
      541 ttatctgatg ggacgcgagg accattttga aatgggcgga gtgtcgacac atgtatatat
      601 tgagttggaa acttcattgg atatggatcg gtttaatcga gcactgcaaa aagttattga
      661 acgtcatgct atgttgcgaa cgattatcct gccgagcgga cagcaacaaa tattagatta
      721 tgttccggaa tatcatattg aggttatccc gatacaggat ctctccaagg aagcccagga
      781 aaagaaaata ctgatggaaa gagagcgcat gtctcactac attttcaaga ccgatcagtg
      841 gcctctattt gagtataagg cttatcaatg ttctgcggaa aggttttacc tttttatcgg
      901 ttatgacatg ttaataacgg atggggcaag ctttcaattc attcatcagg aaattatgaa
      961 attttatcat gatccagatt tagatttgga aggtgtggac attactttca gagactacat
     1021 gatggcttat acgggtttca aatcctcgga aatatataaa agggatcggc aatattggac
     1081 ggataaactg gaatgttttc ctgatcctcc tgctttaccg tatgtttcct caccgagcct
     1141 gattgtacaa ccgcgattca aaagggtaac caaacattgc aatagggagc tttacgaaaa
     1201 gctaaagcaa gtttcacaaa aaaatcacgt gacaccaact gcagtgctgt gtactgtatt
     1261 tgccaaagtg ttgtcatact ggagtaatca atcccaattg gcgctcaatt gtactatttt
     1321 taatcgttat ccatttcata aagatgtata taagatgata ggggacttta catccgttat
     1381 gttacttgac atcacgcttg aaggagggaa atctttctgg gaacagactg aatccgtgca
     1441 aaacgtgttg atggaggcgc tcgaacatag gcactacgac ggaattcaat tcatcaggga
     1501 aataatacgt caacgtggtg ctgaaactca taaggcagcg atgcccattg tattcacaag
     1561 catgttactg gatacaggga aaggtactga tgattctgtt tattatatgg gtgatgtaaa
     1621 aacagcggtt tctcaaacct ctcaagtttt tttagattat caggtcctgg aagtagatgg
     1681 tggactcacg atcacatggg attatgttga acaactgttt gattcagaat tcattaaaac
     1741 gatgtttgac cagtacttta tgctgctgga attttcctta agctcagatg ccggaaatcg
     1801 ttttccttgg ggacatgaaa atcatcttct gatctcagcc tttaatcata cttgtgaaga
     1861 aattccaagg actacactcc attccttgtt tgaacagcag gtcgttcgct ggccagaggc
     1921 aattgcagtg atttataaaa atagccatat cacttatcag gaattaaatg aacgctcgaa
     1981 tagggtggct cgctatttac aggaatatgg cgtatgccgt ggtgatttta ttagtgtatt
     2041 agccaatcgg agtattgaaa ccattgtgaa tattataggt atattgaagg ccggagcggc
     2101 ttatgtaccg attgatcctg attatccgga ggaacgtcgt gaatatatta gggatcacag
     2161 tggttgtaaa ttaatgttgg aaccggatct atacgttaag aaagaattag ccgtttattc
     2221 tggtgaagct cttcaggtcg aacatgatcc tgatgatgta gcctatgtga tttatacttc
     2281 aggcagtaca ggccagccta aaggagtcat tgttacacat ggggcggtag cgaacacggt
     2341 gcaggatata aatcgtaaat tcaatgtgaa tgagcaggac cgtattattg gattatcatc
     2401 catgtgtttc gatttatcgg tttatgatct atttggagcg ttagcggttg gagcggcttt
     2461 agtgcttatt gatgatcaac gtaatattac agaagtcgcc aagacactgg aggaacataa
     2521 aattacaatt tggaactccg tgccagctat aatggacttg atgttgaatc atgtgctggg
     2581 agaagaagag gaaagcggct attactggga tggtaagtat cgctcgtctg gagcacgtaa
     2641 gaaaaacact tctttgcgtt tggtcattct tagtggagat tggatacctc tcagtctacc
     2701 ggataaaatt cgcagacaat attttcacgc gaatgtagta agtatgggtg gggcaacaga
     2761 ggcttctatt tggtccattt attatcctgt atatgaagtc catgaagatt gggcctccat
     2821 accttacgga atgccactag ccaaccaaac ttattatgta ttgaattatg atcaggaact
     2881 ttgtccagta ggtgtaaaag gtgagctatt cattggaggt gttggcctag cgaaaggtta
     2941 tctgcatgaa gaagaaaaaa cggcattttc attctttaat catccgaatt ttggcagatt
     3001 gtatcgcact ggagaccagg gaatcctgaa ttcaaaagga tatattgaat ttttgggacg
     3061 taacgatcag caagtaaaaa tccgtggtta tcgtgtagag cttggcgaaa ttgaaaatca
     3121 aattcttcaa attattggag taaaagaagc agtggtcttg tatactcctg attcaaaagg
     3181 aaataaagta ctgtgtgcgt atattgtggc ccaaccaagt ttgagcattc aggatattaa
     3241 agaaggtatt agtcgtgcat tgccaaatta catggtgccc acccatttta tttgtcttga
     3301 acaaattcct ttaacaccta atggaaaatt agaccgaaaa gcactgccag agccatcagc
     3361 taaaaccata tttcaaaaga aatatgaagc tccagtgacg gagatggagt gccttatggt
     3421 acgaatctgg gaagagattt tggagtatag ttccattagc gtggacgatt ctttatttga
     3481 attaggggtg gattcgacaa gtgtaattaa atttgtggcg agactagcta cagggaacgg
     3541 aatagaactt ccaattcgac aaatttttgt gacaccgact attcgagaat tggcatccct
     3601 agtttcttca tctgagacac agattagtga cctttctaac gaaagaatgt tgtttaattc
     3661 acagggagaa agagaccgaa acatattttg cttccctcct gtagttgcat taggggttgt
     3721 atatcaaagg cttgcggaat tccttggttc ctatcgattg tatagtttta attttcttga
     3781 gattgaacag gaccgtctca tagcagaata tatccgcctt ataaaagaag ttcagcctga
     3841 ggggccttac gtatttctgg ggatttcagc aggaggaaat ttggcttttg agattacaaa
     3901 ggcccttgaa aaacagggag ataaggtcgg ccagctcatt ttattggact cattttacat
     3961 tacagaaata aattcagagc ggcttacaac ggaagagagt cgtaaatatg cgaaagaaac
     4021 agtagacctt atgttgaaaa aatacccaca attacaaagt gaaggagaat tttttcatct
     4081 ccatgttgga gagaagatac agagatacta tgcttatctg gataatttaa tgaattccgg
     4141 acaagttgcg gcccatattc atgttattaa atctcttcag agtcaaagta aacatatccg
     4201 tggagatatc cgaatgtggg agcattctac aattggggag tattccattt gtgatgggta
     4261 tggggatcat gaaagcatgc ttgatgctac atttgttgaa cagaatgcag agttgattct
     4321 aagcatattg gagaaataaa taataataaa aagaggtatt ccatggctat ttcggcctgt
     4381 ggaatacctc tttttaatgg ttgtatccaa acggtctgtc aacctgatat cgtttgtaca
     4441 atgagcacta cattcaagat aatgatgata gcggtcacga tccaggttag tactttttgc
     4501 cacattttat tcgcaaattc acccataatc tttttgtcgc tggtaaaaag cagtaatgga
     4561 atgatggcaa agggaagctg gatggacagg atgacctggc tcagcacaag tagttcctcc
     4621 gcaccttttt cacctgcgat ggcagtgacg atgaccgctg gaataatcgc gatgaggcgg
     4681 gtcactagac gacgcaacca aggtgaaaga cgaagattca aaaagccctc catcacgatt
     4741 tgtccagcta aagtgcctgt aacggttgaa ttttgacctg aggcgagtaa cgccacccca
     4801 aatagtatgc tcgccagtgt ggttcccagt agtggcgaaa gcagataata ggcatcacta
     4861 atttcggcta catctgttct tcctgccgta tggaatacag cagctgccac gatcaagatg
     4921 gcggcattaa taaataatgc gaacatcagc gctatactgg aatcccaagt tgcaaatgta
     4981 atagcttccc gtttacctgc tgaagtctgc tcaaatttgc gagtttgtac aatagaagaa
     5041 tgcagataca ggttatgcgg cattacagta gcgcccataa taccgatggc aatatacagc
     5101 atgcttggat tcgtcaaaat ttgcgagtct ggtacaaagc cgcccaatac gccgccccat
     5161 tccggttgtg ccaaaatgag attaatccca aaacagccgg caatcgtcgc cattagcaca
     5221 atgacgagtg tttccaatgc ccgaaaacct ttgttttgca gcagtaaaat aagcatgacg
     5281 tcaaatgcgg taatgatgac tccgtatagt aacggtagac caaacagcaa cttcagcgca
     5341 atggctgaac cgatgacctc ggccaaatcc atggctgcaa tggcaatttc gcacaagagc
     5401 cataagccga tggcgacagg acgactgtag gcatcacggc acatttgagc caaatcttta
     5461 cctgtggcaa tgccaagctt gccggataag gcttgcagca ggatggccat caggttggag
     5521 attagaatga cactaagcag cgtgtagccg aattttgatc cgccagcgat gtctgtggcc
     5581 cagttgccgg ggtccatata gccgactgcg accatatagc cgggtccagc aaaggcaaga
     5641 aacttccgaa accaggtccc gtctttcggg acgatcaagg aacgattcac ttccgacagt
     5701 gaagcgattt ccgcgaagtt accctttgta tttttcatac gcttcacctt ctttattgtt
     5761 gttgaaatat attattagtg acataacgat tgtgttatct ctattgtaca ctcacaatag
     5821 tttttgtcta gtgcaacttt tgtgtggtca agcaatttaa tcgtattttt gaagcaatat
     5881 ggccataaag ctgaacaata gaaaaaacca agctatatcg ctctgagggg agcggcttgg
     5941 tcgttttgga tttttttaaa ttgttgtcca tcttccaggt gaacgccgct ccatatttta
     6001 tcaatttcat tgtagttatt tggactgaaa cgataaatag cctggtcaat ctttttcttc
     6061 gaatttacgc gtttcagaaa aggccttatt ctccaagttc ggaatcggaa gcattttagt
     6121 catttctatg cctgtaagct tttccaacgc tttgacatag gccatcacat ggacttcacc
     6181 ccgcaccagc aagtaaccta cgatctcgcg tgcgacaggg ttgtcagtca tggaagtctg
     6241 agcagataca ataaaatgat gcgagtaagc cttcaagaca catgttgacg gcccatcaag
     6301 taggggctta taacatatag tgtaaacaag gtgaggtgga attaaacggt gatgtactgg
     6361 ttaacaaccc tatttcaaat gattcatttt gtgtagttcg tttaaagtac atacgagaag
     6421 gaaatcatgt attaacatga cgatagattc ctgcggaaaa catatgatat agagaaggag
     6481 agatgaaatc atggaagcat tatacacagc atcagcaacg gtacatggtg gaagagacgg
     6541 ttcagtcgct tcatccgatg gagttttgaa gcataagctc agcacgccga aggaactggg
     6601 tggcgcaggt ggagaagcta cgaatccgga gcaattgttt gcggcaggct atggtgcctg
     6661 ctatgagagc gcattggcta atgtggcccg gaaggctaag gtgaaggtag acaatgttga
     6721 ggtcaccagc cacgtatcta tcggcaagga cccaagcgat ggcggcttcc agctggcggt
     6781 acgtctggac gtgaaaatac ccggtattga acgcgcccag gccgaagatc tggcacgcca
     6841 agcgcatgat ttttgtccgt attccaaagc aacacgcggt aacattgatg tcgagcttaa
     6901 tgtcatttaa ctgcatttct ataactttta cactctggcc gccgatttat cggtggcttt
     6961 tgcacataga tcttgattcg ctgagatttg cgaccatttg acatcatcgc caaaattcat
     7021 taagatggct taggtgattc tggtcatcag gtacgaaaca aatttgaaaa atacgggtga
     7081 tatgatgtct tacagaccga atattgttaa tttcacgctg gctggcagca acgaaaaaga
     7141 agggctttat gagtttaaaa tgagtttggc cgatggaacg gagtgccgcg ttttttctca
     7201 acgtaatccg gagtggacct tgacgaatat tagtcgactg ctaacgacgc cttgcccggt
     7261 atgccataag gattttatct gcaagtgtat ggataagttt catgaggagt ttttagagca
     7321 aattaatacg aaacagctgt ttgaaaaagc attgagctag ttttcgaaca ggtaaagact
     7381 atacatttct aaacaagcgt cggatacttt cggcgttttt ttgtttatat tcatatggtt
     7441 gcgttgctgg tattcatgcc gttgatttct ctggaggtga aatgcattta tgaaccagtc
     7501 tgatcatgct cgttcagatc attccattgt gttggtggat ggggtatgcc acttttgtca
     7561 gggagcggtc cgctttatta tcaagcgtga ccctaaggga acatttcatt ttggttccct
     7621 gcaatccgag gcaggacaag aactattacg tgcaggagga ctatctacag atcagctgga
     7681 tacgttcgtg ctgattgaag acggtacgta ttatacaagg tccaccgcgg ctttgcgaat
     7741 tgtcaaacgt cttcgttttc catacccgct ggcctatgtg ttcatcctgg ttccccgctt
     7801 tgtgcgcaac gctgtctata actgggtggc gcgtaaccga tatcgttggt ttggcaagga
     7861 tgaagaggat caatgtcaga tccccccacc agaaatcaga caacgatttt tttagttgct
     7921 tttttaagtc tcttttttgg agcgatgtct acgaattagt aagatcacag cgatcacgat
     7981 tagtatcagg ctcgtaacag ctacatacac gatatgtcgt acattgggta cgttaacaga
     8041 caattttagc tcgttagatt ccaaaggagc aatgtcccaa tacagtgttt ttccgtcttc
     8101 cgacacacgg tctgcattat tggtagcagg ttggatgggt aaggataggc tgaagttaag
     8161 atccagctgc cgctccagta atttgcgcgc aaacacattc atttgctcaa atttgtcact
     8221 cagtccttga gcttcttcag gaagcatccg tggtagatcg agcttcatgg taagatcaat
     8281 attcgttgtg aaaaaatgtt gactcacagc gcgctttatt tctaatccct caggtagatt
     8341 taattcctga ctgggatttt ttttgtttgt gctccaatct ccttgataat gtcccttgat
     8401 ttgatatccc tttcttccct gttcagctag cggctgtaca tctacattgt tgctttgaat
     8461 acgcttgact aatcgatcta gcagcccggg attgtccaac atcatcagtg tctggttgtt
     8521 tacactgaac gttgcatcca tatctacact ttgatcgaga tgaacatcta catggatgtc
     8581 acctcgagca caggaagtta ggacaagcag acagcacacc agcatgaaaa tgagcagtat
     8641 ttttcgtatc cgaacttgcc gacatttgtt ccgataaggg ctgtatcctg ttggctccat
     8701 gacctgcacc tctttatatg tattctttgg tttaacgact ggatatcttc tatatattac
     8761 acattgggag aacgaaaatc gaacggtata acgaaataca taagaattat attttataaa
     8821 atgtttccct aggtaaaaac tttagtgtat actctaaaat atagtgttga taaaaaataa
     8881 ttgaatcaag gaaatagttt gtcccaaaac gaaattcaaa ggaggatttt aaaacatgaa
     8941 caagcagttt aagaaggctt tgccgcgatg ggtaacgacg gttggagtgt tgtctctggc
     9001 tctggttcta gcgactgcat gtaccgatgc taagaagaag gagcagggaa ctgcgagaga
     9061 ggcgggacaa aaaataaagg ctacggctac catcggtatg atctctgaca ttgtcggcaa
     9121 ggtcggcggt aatcatgtgg aggtcacagg aattatgaag tcaggcgttg acccgcattt
     9181 gtacaaggct tctcagggag atatgcgcaa gctggatcag gccgacgtta ttttttataa
     9241 cgggttgcat ctggaaggta aaatgcagga cattctggag aaaatcagca agcaaaaacc
     9301 cgtcataccc gtgtccaaaa acatcgcaca ggatcagttg cgtgcaggta gcccggaaat
     9361 gggatctgag catgatccac atatctggtt taacgtacag aattggatgt ctgcggtaga
     9421 aaccgtcaga gatgaattat cggcgctaga cgctgttcat gcggaggaat ataaggccaa
     9481 cgcagaagcc tatcttactg agctgcgaga gctggatgat tacacgagag agcagattgc
     9541 cagtataccg gaagcccagc gcgtgcttgt cacagcacat gatgctttcg gctatttcgg
     9601 agatgcctac cacattcaag tgagaggact tcaaggtatg agcacagagt cagaagcggg
     9661 ttctcaagat gtgaccaagc tgcgagatta tttggtggag cataaaatca aggctatatt
     9721 cgtagaatct agtgttccga gaaaggccat agatgcggtt attcaggggg ccgctcagca
     9781 aggccataca attagggttg gtggcgagct gtattcggat gccatgggtg aagagggcac
     9841 agaagatgga acatatattg ggatggtcaa gcataacgtc aatacgattg ttaaagctct
     9901 taaataagga ggcaaagata catggggcat tcaccacttg tcgttcgtga tttatcggta
     9961 gcttatcaaa aaaagcccgt tttgttcgat gtttcctttg aggtgccgga aggcaagctg
    10021 attggtatta tcggcccgaa tggggctggg aaatctacgt tgatcaaggc agcgcttgga
    10081 ctgattccaa agcttagggg cgaggtgctg gtctacggca agccctataa gcaacagctg
    10141 ctcaaggttg gctatgtacc gcagcgggag tcggtggatt gggattttcc gacgaatgcg
    10201 ctggatgtgg ttatgatggg acggtatggc agattgggct ggtttaagcg tccaggtgca
    10261 gcagatcgtc aggctgcgat ggagagtttg gacaaggttg gaatgagcaa atatgcagac
    10321 aggcagatta gtcaattgtc tggcggtcag caacaacgtg tttttttagc cagagcactg
    10381 gcgcaagacg ctcagcttta ttttatggat gaaccgtttg tcggtgtgga cgctgcaaca
    10441 gaaaaagcca ttatttcatt gctcaatgat ctgaaacagc agggtaaaac cgtgcttgtc
    10501 gttcatcatg atttatctac agtcacggat tattttgatc aggttatgct gttgaacggg
    10561 catcttatgg cgtttggaga gacgacagat atttttaccg aggaaaatct gcagcgtacg
    10621 tatggcgggc gtctgagtat actcaaaaca ggcccggatt ccggcacgat actcggagtg
    10681 aggtgagcag tatgacaagc ttggcaacgc ttttgaccga cccaaacatg cagtggattt
    10741 tgctgggctg cattttgctc ggtttaagca gcggggtaat tggcagtttt atgtatttgc
    10801 gcaagcagtc gctcatggga gatgctttgg cacatgcggc tttgccgggg gtatgtgtgg
    10861 cttttatgat cacaggtaca aaatccgtgt ttggatttat gattggggcc gccattgcag
    10921 ggattgttgc gacctttgct atcagtgcgt taacccggta ttcgcgaatt aaaagcgatt
    10981 cggcgattgc agcggtgctg tcggtatttt ttggcttcgg cattatgttg ttgaccgaaa
    11041 ttcagcatag tggcgcagga aaccaaagcg ggttggataa atttctattt ggtcaagctg
    11101 cggcaatggt attgtctgat gtctacacga tggcggtaat ttcggtggta ctcatcggaa
    11161 tatgtatatt atttttcaag gaatttaagt tgctcagctt tgatcccggc tttgcccgcg
    11221 gacttggtta tccggcaggg ttgctggata agttgttgat gcttttgatt gtcattgcgg
    11281 tggttgctgg cattcaggcc gtgggagtca ttatgatggc tgccctgctg attaccccgg
    11341 ccgtgtcggc aagatactgg acagagaagc tgggtgtcat ggtatgccta tcaggcttgt
    11401 ttggtgctat agcaggcctt ggtgggacgc tcattagctc tctggggcaa aatctgccta
    11461 caggaccgtt atgtgtgttg tgtgcgactg tggtgtttgg aatgagcttg atttttgcgc
    11521 cgcagcgcgg gatgatctcc aaggctatcg ttcggttgaa cgccagaaaa aatctggagc
    11581 agacagtcgg aacacagcca agggaggagc gtgccctatg agttcatttt atgtaatttt
    11641 gacgggaatg ttagtggcag ggggatgtag tatcgttggg tgctttctcg tgcttcgaaa
    11701 aatggctatg atcggtgatg caatcagtca tgcggtattg ccggggattg tcattgcctt
    11761 tctcatcagc ggatcgaggg attcggtgtg gatgatgttt ggtgcggctg tgctgggtct
    11821 tctaacggtg tacctaattc agctattcca acaaagcggt ctgcaaagtg atgctgccat
    11881 tggcgtggtg tttacgacat tgtttgctat cggtgttttg ctgatcagtg tgtttgcttc
    11941 caatgcccat ctggacatgg atcacgtttt gtatggggaa attgcttatg tgccatggaa
    12001 tacgttcgag attgccggct tcgatgtcgg tccgagggct gtgtggatta cgggcgcgat
    12061 gtttttgatc aatttgctcg tgataggggg ctttttcaag caatttaaaa tcacttcctt
    12121 cgaccccgcc ctggcagctt cattaggcat tccagttgtt ttttttcatt atctgctgat
    12181 gagtctcgtc tcgttaacga cggtggcgtc atttgagagc gtgggtgcaa ttctggtggt
    12241 tggcatgctc gttgtaccgc ctcttaccgc ttatttgctg acggagaagt tgtcccgtat
    12301 gattgtatac agcgtcggat ttggagccat cagttcggtc gtaggctttt acacagcaag
    12361 tgtattggat gcttctattg cggcatgtat gctatgtgta tcgggtgtgt tgctgctttt
    12421 ggcttttctc ttttccccgt ctcacggtgt ggtatggcaa aagttatttc aacaacgggg
    12481 gatcgttggc gaagatagca agtgattgta ggaagtgatc ccatatgagt tacccaaaat
    12541 agcgtgcatt caggcataag agacctgaat gcacgttttt tgcgcttata ctgccctgtg
    12601 cggctttttt tggggcaagc ttgattgatc atcttgaatt gattgggaca cgggagtaca
    12661 ttcattacaa ctatataaga atggacggaa caaacaagca cgctgtgggg aggaacgaaa
    12721 gtggagagct tcaaacgtaa atcaccagag gaaatactgg attcgattaa caaactgcat
    12781 cgaggcagac tcaaaatata catgggtgcg gtcagtggct cgggcaagac gtatcatatg
    12841 ctgcaggagg gacaatcgct gcagcatgaa ggtattgatg ttgtgatttg tgcggtctca
    12901 accatgcagc ggcctgtgac cgtggaacag gtcggcacgc tggagcgagt gcctagtatt
    12961 cattggataa aagatggtga ggagcagaag gatctgaatg tggaagcttt ggtggcgcga
    13021 aatcccgagg tggtactggt ggatcatttg gcacatcata accggaaaga cgctccattc
    13081 ccaacacggc tggaggatat tcggtatttg ctggagcagg gaattagcgt cattacgacg
    13141 gtcaatgttt atgaactcga aggaattacg gagtgggtat atcagctgac aggctttgaa
    13201 gcggaatata cggttccggt tgatacgctg gagctggcgg atgaaattcg tctgattgat
    13261 gccaccccgg agatgatttt ggaacggctg gcgaaaggct acatgcatac gtccaatcct
    13321 gagatgtttc atcggggaaa tctgggtaaa ttgcgtgagc tagccctgcg attggtagca
    13381 gaggatgtga atgattcgct ggaacggcac cgggaggagt taggcttgca cggggcctca
    13441 ggagcagcag agcgtatttt ggtacctgtc caatatcatt ggaacgggtc catttatgta
    13501 cgcagggggg aacaggtcgc caagcggttg ggtggagata tgcttgtagt ctcctttgtt
    13561 agctcgaagc gaaagctgtc caaggaatca gcagccttca agcgttcgat tgagcagttg
    13621 gctgacaaga taggatcgac atttgaagaa attccgcttt tttctcgcag aaggttgcct
    13681 cgtcaactga ttcattatgc ggtgacgcac aatgttaccc gaattgttat ggggcattct
    13741 cggcagactc cgtggcagga gctgatgaaa ggatcgctgg tgaacgggat tttaaaacga
    13801 atgaaaaata tggatctgct gctgattgcg gaccgggccg agcaggaggg tgagcggatt
    13861 ttgccaacga tgagacagga ggaaggagat aatgatccgt atcatcgttt gagcgttgaa
    13921 gaagcacagg ctgaggcagc caaaatcctg cggggcaagc tcaaggtata tattggcgct
    13981 gctccgggag tcggcaaaac atacacgatg ctgagagagg ggaatgatct gctggagagc
    14041 gggatcgatg tagttattgg actgctggaa acgcatggaa gagcagaaac actggcacaa
    14101 gtaggctctc tggagatgat ttcccgtcag tccattgagc gtcatggcgc acacttggaa
    14161 gaaatggaca ccgaagccat tctcaggcgt aatcctgagg tagtgcttat tgatgagcta
    14221 gcacatacca atgttcccgg aagtctgaga actaaacgtt atgaggatgt actgaccatt
    14281 ttggaacaag gtatttctgt gatatccaca atgaatgtac agcatctaga gagcttgaat
    14341 gatgcggtgg aacagattac tggtatacga gtgagggaga ctgttcccga ccatatgatg
    14401 cgtctggccg atgaggtaca gcttgttgat gtggctccta aatcgttgca gcagcgtatg
    14461 cgtgaaggca aaatatacga tcatgcgaag gtggaacagg cacttagcca cttttttaaa
    14521 ctgggcaatc tgattgcgtt acgtgaactt gctttgcggg aattggcaga tgacgtagat
    14581 gagcggctgg aatcctggga tcgacatgaa tcacttcggg gaccgtggcg cagggaggaa
    14641 gtaatcttcg taggcgtgac gctaagtgaa aatgctgaaa ggttgattcg ccgtggtttt
    14701 cgtatcgcct ttcgtctgaa ggctgtgtgg attgtgactt atgctcatgt cggtgagcgt
    14761 atacctgaga gactgaaccc tcgtctggaa caactaaagt tgctgaccca ccgactgggg
    14821 gggacctttg agatacggct tgtttccagc cgacgcgaga ttgccgacat tttgattgct
    14881 ccagtggaag gatattcagg tacgcagctc atcgtggggc agtcttcccg aagtagccgt
    14941 tgggggaagg ctgcggttgt gccgaggatt ctccgtcaag cacgtcatat ggatgttcta
    15001 attgtggcgg attatgatcc ggatattaag cttgaggtag atcattaatt cgcccagtaa
    15061 attcataaat agtcatatgc tggttaccga tggttcgctg cttccatagt atattctatc
    15121 tcaaagaaat ggaggcgaat ttgaatgtat aaacatcgta agcatgattg tcattttcca
    15181 aagccaaaaa aacgtgtctt taagaagatc attaaggtga ctgtcattaa gtttaaacct
    15241 aaatttaaac gtgatcactg gaaacatgaa gattttgata agaaatgtca ttgcaagaaa
    15301 cgtcgccatc atcgccatca tgactgtcat cgtcgtcacc acaaattcta ctaagatgaa
    15361 gatagtagga ggcggggcta gactgcccgc cttctcctag tacgaggatt ttggaagata
    15421 cttgcacaaa aaatacttgc tctaatataa gcgctatgct attctaccag taaatagatt
    15481 gcacgtgacg gaagcaccgt tcaccaaccg tatgtattta cggatggatg aacggtgctt
    15541 ttttgcgttg ttgtgttagg gaaagggatg agcgttatgg ttccagtgaa agtggtattg
    15601 gccgtagaag gccgggatta tattgagccg ctgctgaatt atgttcacgg aagcgagtac
    15661 gccagaaggc tgagaataac ggctttttcg caaccggagg catttcatca atacatgatg
    15721 gaaaccagcg gaatgaaaag accggatgtg gtggtgggtg aagcggcttt tttgaatcta
    15781 tggacagaca gggaagctgc tgatattcct tgtttggtat tgcatgaggg agaacaagtg
    15841 gacgaatatg gacagctttt attaaaatat cagcctttat ctgagctggt cggttttatt
    15901 ttggaaacgg ctagacagag gtcgaacggt cggaaaagtg taaacagtcg ggaaggtgga
    15961 atgattatcg gcatggtagc agcttccggt ggactaggta agacaacggc cgcactcaat
    16021 atgtccaaac agctggggaa tgagggatat tcggtattct atctgaatct ggagacggtg
    16081 gattcaagct cgttgttcac tggttcaggc agtgctagcg gagcagaagg agaagggctg
    16141 tccaggctgc tctatgatct caaggcgggg gggagtgagg acactccatt atccatggct
    16201 tcctattgta ttcgtcgccc tgaaattcag gcggatactt ttcagcctgt ctataatcgc
    16261 aaggagctga cggacatgac ttgtgatgaa gcgaaagagc tgattcgaac ggttgccgaa
    16321 agtgggcagt atgatgtagt gatcgtagat ggcgattctg aaaaaggtga tcgggctcaa
    16381 gccgtgcttg aagctagtca taagctgatt tggctgctgg cagacgattt aatgagcatg
    16441 cacaagtgcg gattatggct ggatgtttta gaaaccacgc agcctgaagg gcttgaagac
    16501 atgatatgca aaaccagctt tgtggtgaac cgctatatgg gaactatgat caactcatta
    16561 cctcgtgact tcatggagct aaacggagcg ttaccctata taccttcatg gaagcagatg
    16621 caacaccgtg agctactgct tagttcaccg atttatcagc gggaaattcg tcatctgtgc
    16681 cacgagctgc tgaatgtgga cagtgtaaca catccgcccg ccgtttggtc ttaaaagggg
    16741 ctgatgaaca tgaatgagga acggtttaag gcattgcgag cagatatccg aaacgggctg
    16801 gacgtaacgt cttcggtaaa ggatgcagat ctggtacggc atattgaaaa tcgaatttta
    16861 cacgatgtag agctggtggg cttaacttcc cgagagaagc acgcacttgt gcgcaagatt
    16921 tttaactctt tccgtgggct ggatgtactc cagccattga ttgacgatcc gaccgttacg
    16981 gaaattatga ttaacagtca ccgggaaatt tttgtggagc gggctggtga agtgatgcag
    17041 gtacctgatc aatttgagtc ccgcgagcgg ctggaggatt taatccagac gattgtagcc
    17101 ggggtgaacc gaattgtgaa tgaggcttct cccattgtgg atgcccggtt aaaggatggg
    17161 tcacgcgtaa atattgtgct gcctccagtt gctctcaagg gtccgacgat gacaatacgg
    17221 aagtttcccg agcgtcctat gacgatggat gacttgatac aaatgggtgc gcttgatgca
    17281 gaaaccgctg ctatgctcaa ggacttggta cgtagcaagt acaacatttt tataagcgga
    17341 ggaacgggtt ctggtaaaac aacttttctg aatgcattat cccagtttat cccgtcgtct
    17401 gaacggatta ttaccattga agactcagca gagctgcaaa ttgtgacggt ccctaatcta
    17461 gtttccatgg aaacacggaa tgcgaacacc gaggggaagg gagaaatcac aattcgtgat
    17521 ctgattcgtt cctccctgcg tatgcggccc aaccgcattg tggtgggtga ggtccgggga
    17581 agtgaggcat tggatatgct gcaagcgatg aatacaggac acgatggatc gttgtcaact
    17641 gggcatgcga ataatatccg cgatatggtc agccggctgg aaacgatggt gctcggagga
    17701 gcagagcttc cgcttggagt agtacggcag cagatcagct cagctattga tatattcgtt
    17761 catctgtcac ggatgcgcga caaatctaga cgagtgctgg aaattagcga agtgattggc
    17821 tttgaaaatg gtgaggtgac gcttaaccct ctttatcgtt ttcaggaacg aggagaaagt
    17881 aaggggcgaa tcgtaggagg tctggaacgt tgtggcgagg gtctgcaaca tactttgaag
    17941 ctgcaaatgg ccgggatcaa tccggaaaac tggcacaggg gaggagtatc agcgtgaagc
    18001 caggaaaaac gactgccaag caagtatcac gtgaggtccc ttctctgcca gattatacgg
    18061 tatatacatt atcgacagta caaaaaagtc tgtgcatatt ctttagtggc gtgctgttcg
    18121 caatgatcgg ttatctattt tatcaccaat ggatattatc gttgctgtgc gctgccgggg
    18181 ctggggtgac gcctcgttat tttaggcaat ttttgctgca tcgacgcagg tctgctctaa
    18241 gcatccaatt caagcaggct ttatattcgc tctcgtcttc tctttcagcg gggaggtcgg
    18301 tggagaatgg ttttcgtgag gctgtagagg atttaagatt gcttagtcca gatggagatc
    18361 acgacctgat ttttgaattt aacatcatta ccgcctgtct cgaaatcgga cagcctgtag
    18421 aggctgcttt gcaggatttg gcccgtcggg cgcagatgga ggatattacg aattttgcgg
    18481 acgtatttgc ggcttgcaaa cgaaccggag gtgatctggt ggaagtcgta cgacgagctt
    18541 caagtgtcat tggtgagaag ctggaaattc agcaggagat tggtgtaatg attgcgcaga
    18601 aacgttttga atcaagggtt atgtttgcgg cgcctttttt gtttgtatta tttatgacaa
    18661 tgacagcggg tgattacatg atgcccttat acagcggtac aggtatgatt ttatcaacct
    18721 tttgtttatt ggtgcttggt gggtgtcttg tgtggatcaa ccacattatg aagattgaag
    18781 tgtaaggaga gatgggtgtg gtgatgttgg tttgtctggt catgctggtt ctgcaagtgg
    18841 gaggctgggt ggtgctgaac cagatgcatg gtgctaagta tgcgcatttt cgccatatga
    18901 agctggaggg actgcggctg caaagacttt cagtcccatt tgtacacatg attcatgctt
    18961 cacgtgctac tcacaggctg cctttgctga tgttcaagct ccagcgttcg gtgcagaagc
    19021 tgtatggtat gcgcaacagc ggagaaaaaa cgatgctttt tctggcagaa atgttgggtt
    19081 acggatatat gatggctgct ggtggagcta taatatcgct tatgctgggc ggggatgcga
    19141 ccgggctggt gctcggattg ggacttggta ttctggtacc catcgcgctg atcaaggatt
    19201 tgcatgggaa agtacagaag cgggatcagc aaattttaat ggaactgcct gaactgttga
    19261 gtaaaatgat gcttttagta ggtgcaggtg agacggtaca acgggcattg ctacattgcg
    19321 tggaacgtaa aggggcggat acggaacatc cgttgtatcg agaactgagg cagacggtgg
    19381 gggaatggga aagcggctat tcctttcaac aggcatttga gcacctgagc aaacgttgtg
    19441 gcattcagga aatgacagta tttacgacga cagttttgtt gaatatgagg cgcggcggga
    19501 gcgatttcgt gatggcttta cgtgagttat cccagacgtt atggggcaag cggacttcaa
    19561 ttagccgcac aaggggggag caggcttcat ctaagctagt attcccgatg gcgctgattt
    19621 tgctaacggt aattgtgctg gtgggcgctc cggctttaat gatgatgaat atgtaggagg
    19681 aataaaacga tgatgacatt agtaacaggc agtattcgta aattgtacaa gggtgaggat
    19741 ggtctgggta cgttagaaat gatcctgatc attgccattc tgattgcggt ggcaattatt
    19801 ttcaaggatc agatcaagaa aattgtagaa gggcttttga aaaaggcgga taaaaaaagt
    19861 aacgatttta tggattcata atgctacgca aattggcaca aaaagaggac gggagcttct
    19921 ccttggaagc ttccctcgtc tttcccattc tactgctggt catttttgtg atgttatttt
    19981 tttgcctgta catatatcaa aaatctatat tggtgcaggt cgctgctact gcttcggaaa
    20041 gggctgctta cagttgggat aacagcttca aggacccgcg tacgggagca tttatgcaag
    20101 ggcaacggga ttctctctat tggcgcttga aggatgatgt tatgctggga gccctgtttg
    20161 gctggaccgg agccaacaat caggaaagtg tacaggtgcc gggcggcaat gggggaggct
    20221 cgttacctgc tcaaaagctg tccaatgcag aaaataatat gcctgcgggc atgcaggggc
    20281 agatgacata tgagaacagt atgattcacc gtaaggtgat cacaaagtta aataagatag
    20341 tgaaggtacc tttgttgaat cagtttttag atcagacaga tttgcaaggg gaaatgagtt
    20401 ctggcgtggt cgaacctgta gaatggattc gtacggtgga gttggtccgt tattatggtg
    20461 cgaagttatg ggcagaggat caggtgaaaa ggtagattcg gcagttgtag ggaaagtatt
    20521 gatgcaatat ggtcaaaatg gtcagtgaga agtaagtaac gggaatgtaa ctggaaagga
    20581 ggaagcgggt gtttggtaag ggacacaata caaaggacgg ggaatcaggt gctgtcacgg
    20641 tctttttaat tctgattttg gcggtcatgt tcggttttat tgctgtattt attgattacg
    20701 cgagaattgc tgcactgcat gtgcagaccg aacggctgac ccatgcggcg gttcgttcag
    20761 tgatgtctgc ttatgatccg acattacaac aggagtacgg tttgtttgct tatggcgaag
    20821 gcggcggaga acaaattatg gtcaaagtgc tcaatgacag cgcgcggcgt acggcacgtg
    20881 cagatacgct accgcttatg aatatgaagc tggattctag ttccctgcaa atggaaaggg
    20941 agcttggtaa atatgccata tttaacgagc agatccgtga agagatgaag tataaagcac
    21001 ctgtagattt tacatttgaa gtgctcgaaa agctaaagcc gctctctcaa aatatgaaag
    21061 aggcttctca tacggtagat ttgctgaaaa ggctgcaaaa gctgtacgac agacgagagg
    21121 ccaaactgga tgacatgctg gagaagcagc gtaaggcagg agcttatatg gaagaggttc
    21181 gcaagcggat tattaaacag aggggcactt atatgcccaa tcagtatata tgggacccgc
    21241 ttgaggttgt agccgatatt gccgctcaat ataagcatta cgtacatgta tatgaagata
    21301 acaagaagag tgtggacgac gttaaaatca tgcagatgga aaaatatgca cgtagagcga
    21361 gggcagcgct tgatcgcctg cgtcagatca tggttcaggc tggagaagaa catgataagc
    21421 tgcttctgga agccaaggaa ccgttaaatg aggcccaaca gattaatgaa gagatgcgca
    21481 aagtcattgc ccaatataag cagagggcgg ccaatgcagg ctacgatgag gtttcagcag
    21541 cccctacttc aagcggagca ggctccaacg cagatccgtc ggtaggaagc gcacggcaaa
    21601 aagcagagga tttgttgatt ccagacaagg aatttgagca atgggaagca gaaatcgaaa
    21661 agcaacggac ttctataaat actgctaaca atataataac gagcatgatg cgtaccttat
    21721 ctttttatac agatccattt ttgaatgcag atatgctcaa gcaagaagtc gcatcaacgc
    21781 tcaaagagat agataaatac ttgaatgcgt atgcttgggc gggacctgcc aatgtactcg
    21841 atggtgaagc caaaatgatg gatacgcgac gtggaccgga caaagaacgc aagaaaatgg
    21901 aaaaagaggc gaaaaacaag ctcaaacaag cctatcggat cattgaggtt ctttccaaag
    21961 gtaaacaaag tgcagaacaa ttccaaaatc tggagcggta ttacaatgaa agtatttcgt
    22021 ttaaccagtc tacatccagt ccatctgtat ccgctgattt gccctatgac acctatgatg
    22081 cagtgggagc ttccatggat agtatggatg gtctatacgg gtcggcatcc aatttactga
    22141 ctcaactggg agacgagttt taccagaatg aatatgcgct ttcttacttc catcatgtgg
    22201 attttagccg ttttggcagt ttggccggat cgggtggaaa tgtgggaaat gctgcacaga
    22261 ttttgggaga tcagctggag gtgaataatc aggaagttga gtacatcctg tatgggttcc
    22321 ataatccgac aggcaatctg gcatccgcct atggagaaat tttcgctatg agacttgcca
    22381 ttcgaacaat ggagggattg gttaaaaaca gctcaaaagg taatccgctg gtcgttttgg
    22441 cggcagcttt gttatatgga gtagaaaaag cgatagaaga tatgattatg ctggcacaaa
    22501 agggggacgt gccattgtct gattttctga aatttcgaat gacatacaag gatcatttgc
    22561 gattgttcct gatgctccat agcaataatg aacgaaaaat gtcccgtatg cttgctctga
    22621 tccgcctgaa tacagatgtc aatcctgctg agcggcaaac gtatgcaacg ggtgaagtca
    22681 ggaatgggat gaggctgtgg tttctacctg gggtaatgaa aatgctcggg accgcctcaa
    22741 aagaaggcga gagtattaag ggaagtgtgt actatgtcac gaaaacagcg catttttcct
    22801 attaatcggt gtttacggaa agtttgtggg cagaagcaat gtgaacaagg aagtattgtt
    22861 ttagaagcgt cactggtgtt gccaatgttt ctgtttttta ttatttttct catttatatg
    22921 gttcagatga cgctggtatc cacagccttg cagaacaccg cttcagaagc ggttaagcag
    22981 gtttcgacta aaatctaccc agtttctcta gccgtggagg cggcgtccgc gaaaatagat
    23041 acagtccgtg aaccgatgga tgaattgcct aggttatctg tgagtgaata tgcaagccaa
    23101 ttcgctgccc agttgccacc tccaattggt gattgggtag aaagcgctgt tcagggcggt
    23161 caaaagccga tggaggagct gcgggggcga tttacggaag ctgcacttga ccctgttctg
    23221 aagccgatgc taaagccttt tatggaggaa agcattctgg agtatgaccg tattcatgta
    23281 acgagcatac atgtacctgc tcttacagga actaaggacc cttattttag agtagagctg
    23341 tcgtatgaac tgccgatgaa ggtccccttt ctgtatcgca gcattgtgct tcaggcggcg
    23401 gcagaggaac gtctttggat tggcgacaca ggggagggga caggtacaga agaggcaaca
    23461 gcggataagg atgcgcagca ttccatacag ttgctcgtca agcctgaacc tgctgtgaag
    23521 ggtgtgtaca atttgatcaa ggccaaggtt gagcctggga agactgctaa cctttctgta
    23581 ctttacaagt cgggtgagag cacagctcag cacttgggct ggacctctgc caatgtggac
    23641 ggaattattg aatggaactg gtttgtggga acgaacacaa cacccggtca atggagcttt
    23701 gtgattgaaa cggaggacgg tcaacgtata gaagttccgt ttaccgtgga aaagccagct
    23761 gatggataga taggatcgac tcgacataga cggacaggaa taactacgat ggaaaatgat
    23821 ttggcagtct gctagttcta ttttataaag ggggatgacg tggatgtata ttgtatgcgg
    23881 agttctgctc gcgattgcgt tagttacgga tttacgtagc atgaaaatcc ctaataagct
    23941 tacattgccc ggcatagtgg taggcttggt gttcaatact ctgcttggag ggtggcacgg
    24001 ttttttattt gcagttgctg gactgggtac cggatttggt ttcatgctga ttttgtactg
    24061 gatgggagct gttggtgcag gagatgtaaa gctattcggc ttgattggag catggactgg
    24121 tgccgctttt gcatggcagt cagctttata ttcgattttt tttgcaggta ttattggcat
    24181 aggaattttg ctgtggaaga gggaaaccat catgagactg cggcgcgtgg cttttaattt
    24241 aggaggattt tttctatttc gcagcggcaa agcgctgacc agtggaaatg aagcgcacct
    24301 caggtttcct tttatgacgg cagtcattcc gggagcgat
//
